PHARMACEUTICAL JOURNAL.
• . I
ESTABLISHED 1841.
A Weekly Record of Pharmacy and Allied Sciences.
FOURTH SERIES-VOLUME IV.
COMPLETE SERIES - VOLUME LVIII.
JANUARY TO JUNE, 1897.
LONDON :
PHARMACEUTICAL SOCIETY OF GREAT BRITAIN,
17, BLOOMSBURY SQUARE, W.C,
Z{
W. I. RICHARDSON, PRINTER,
4 AND 5, GREAT QUEEN STREET, LINCOLN’S INN FIELDS,
LONDON, W.O.
July 3, 1897.]
INDEX.
[Supplement to
Pharmaceutical Journal.
INDEX TO VOLUME
A
Aberdeen and North of Scotland Society of
Chemists and Druggists, 157, 362, 504a.
_ Junior Chemists’ Association, 219, 262,
283, 302.
Acaroid Resins (Tschirch and Hildebrand),
370.
Accuracy (Sutherland), 218.
A. C. E., The Keeping Properties of, 484.
Acetic Acid as a Menstruum (Remington),
288.
Acetone, Assay of (Kebler), 161.
— Collodium and Oil of Cade (Gaucher),
314.
Acetylene, A Bunsen Burner for (Munby),
423, 469.
— Explosions, Products of (Bone and Cain),
287.
Acid Fixing Bath, 244.
Acidity of Moorland Water, 200.
Acid- loving Fungi (Wehmer), 289.
Acne, Formula for Ointment for (Boeck),
158.
Aconiti Folia, The Histology of, 170.
— Radix, The Histology of, 170, 230.
Advertising and the Press, Editorial Remarks
on, 51.
Agar Agar Gelatin, Formula for, 396.
Age of the Earth, The, as an Abode Fitted
for Life (Kelvin), 517.
Air-bubbles in Slides, To Avoid, 140.
Air, Liquefacii n of (Hampson), 287.
Airol in Leprosy (Fornara), 363.
Alchemy, Modern (Gardner), 191,
Alcock, F. H. — The Studies of a Fha ma-
cist, 380.
Alcohol-produciog Ferment in Yeast (Buch¬
ner), 288.
Alcohol and Non-Exciseable Drinks, Mr.
Lough on, 473.
— in Chloroform, The presence of Water
and of (Behai and Francois), 465.
Alcohols, The Colour of, Compared with
Water (Spring), 417.
Algae, Evolution of Green (Chodat), 468.
— Food Materials of (Molisch), 289.
• — Preservirg the Colour of (Sturch), 385.
Alkali Works, The Annual Report on, 497.
Alkaline Iodides and Bromides (Knoblocb),
460.
Alkaloids (Hoseason), 96.
— and their Salts, Note on the Drying of
(Dott), 21.
— of Calisaya Bark, 504.
— The Determination of (Farr and Wriuht),
202.
Allen, William, and the Duke of Kent, 476.
(FOURTH SERIES.)
Alloys Containing Zinc, On the Freezing-
point Curves of (Heycock and Neville),
238.
— Formulae for Fusible, 464.
— Recent Work on, 151.
— X-Ray Photos of the Solid (Heycock),
423.
Aloin, Determination of (Schafer). 287.
Alpers, W. C. — Gelatin Capsules, 25, 66.
Aluminum Condensers (Norton), 290.
— Goods, The ILe of, in the United States
of America, 568a.
Amateur Prescriber, The, at it Again (Locul),
200.
American “Pharmacy,” Remarks on a
Picture of, 184.
Ammonium Sulphocyanide not Poisonous
(Htffter), 184.
Amygda1®, The Histology of, 170.
Amylum, The Histology of, 170.
Anaesthetics and Narcotics, Notes on the
Uses of, 88.
Analysis of Fatty Oils, The (Cowley), 329.
— of Trade Gin, An, 426.
Analyst’s Omission, A Public, 496.
Analysts, the Danger of Public, Editorial
Remarks on, 535.
— The Society of Public (Annual Dinner), 53
Analytical Differences, Remarks on, 53, 298,
378, 421.
— Work, Apparatus for, 504.
Anethi Fructus, The Histology of, 230.
Aniseed, A Dangerous Adulteration of, 399.
Anisi Fructus, The Histology of, 231.
— Stel ati Fructus, The Histology of, 231.
Anniversary, Editorial Remarks on the
Society’s, 447.
Anozol or Deodorous Iodoform (Diaz), 422.
Answers to Queries, 20, 40, 60, 80, 100, 1 .0,
140, 160, 200, 224, 244, 266, 286, 306,
326, 346, 366, 386, 408, 463, 483, 503,
524, 544. 568.
Antbemidis Flores, The Histology of, 269.
Anti-Cutting Movement in the Photographic
Trade, 472.
Antiquity and History of the Mortar, The
(Thompson), 267.
Antiseptic Pellets, Soluble, 8.
Antitoxic Serum (Behiing’s) in Diphtheria,
On the Effects of. 43.
Antitoxin, Electrolytic Diphtheria ( Smirnow ),
368.
— The Use of Diphtheria, 476.
Antitoxins (Gamble), 340.
Anti-Vivisection Society and the Prince of
Wales, 536.
Ants, Solutions to Drive away, 335.
Apatite, Canadian, 5U2.
Aperient Syrup, Formula for, 326
Apothecaries Act, Proceedings under the, at
Sheffield, 405, 414.
— Society, Course of Botanical Lectures by
Prof. F. W. Oliver, 453, 522.
Appliances, Novel Pharmaceutical, 406.
Application for Sycosis, Formula for an, 425.
Apprentices in Drug Stores and Self-Medica¬
tion, 558
April, The Flowers of, 296, 336.
Aquarium and Microscope, Curiosities of
the, 335.
Argentol, Composition of (Fritzsche), 369.
Argon in the Blood (Regnard and Schloesing),
161.
Armoracise Radix, The Histology of, 269.
Army Compounders as Public Dispensers,
Editorial Remarks on, 131, 237.
Arnica Rhizoma, The Histology of, 269.
Arrow Poison from Larvae (Boehm), 468.
Arsenic Flue, Death Caused by Falling into
an, 80a.
Arsenical Soap Case, Houghton v. Taplin,
77, 415.
— Soap, Claim against Manufacturers of,
415.
— Soap Crusade, The, 13; (Barnes), 19; 53, 72,
77, 120a, 415, 420 ; (Harvey), 462.
— Water, Export of, from Guber, 38 4;
Artificial Wine, 602.
Asbestic (Jones), 468.
Ashton, C. S. — Ancient Pharmacy, 138.
— C. S. — An “ Enquirer’s ” Question An¬
swered, 462.
— C. S. — Chouan Seed and Autour Bark, 408.
— C. S. — The Latin of Pharmacy, 305.
Aspidin (Boehm), 288.
Assimilation of Nitrogen (Laurent, Marchal
and Carpiaux), 289.
Assistants I have Met, Some (Morgan), 321.
Assistants’ Qualification Wanted, An (McMil¬
lan), 345 ; (Bessant), 364 ; (Longstaff),
(Saltpetre), 365 ; (One who Respects
the Major Qual.), 385 ; (Glass), (A Young
Major), 407; (Currie), (Nil-Desperandum',
427.
Atkinson, Leo. — The Council Election and
the P.A.T.A., 483, 523, 568.
Atomic Theory, John Dalton and the (Cock-
shot), 61.
— Weight of Carbon, On the (Scott), 280.
Atropine in Diphtheria (Elsaesser), 58.
Attfield Testimonial, The Proposed, 113 ;
(Moss), 305 ; 497.
Austin, Josiah — The Proposed New Bye¬
laws of the Pharmaceutical Society, 264.
Autosprays and Autoclaves (Medico- Hygienic
Inventions Co., Ltd.), 197.
Autour Bark, Chouan Seed and (Pharmacist ),
384 ; (Ashton), 408,
Supplement to
Pharmaceutical Journal.
B
Bacteria and Chemical Reagents (Paul and
Kronig), 162.
— and Disease (Thompson), 85.
— Fossil (Renault), 162.
Bacterial Diseases of Plants (Peglion), 162
Bacteriology (Richardson), 96.
— Book on, 568.
— in 1896, 17.
Bailey, H. H. — The Benevolent Fund, 198.
Balance, Novel Dispensing, 8.
Balls for Dysentery, etc., in Lambs, 504.
Balsam of Tolu, A Snurious (Braithwaite),
307.
Balsamorrhiza Terebintbacea (Sayre), 289.
Bankrupticies, 428 a, 484a, 504a, 524a.
Barclay, John — The Coca Wine of Com¬
merce, 341.
Birks, Compaiison of Rhamnus (Sayre), 288,
Bailey, Germination of (Gribs) 163 ; (Dav),
290.
Barnes, J. B.— Arsenical Soap, 19.
Barrass, T. E. — Oa Counter Prescribing, 244.
Barrett, J. T. — The Protection of Prices, 8.
Barrett, W. L. — The Students’ Page, 79.
Bartleet, J. — On Check Tills, 224.
Basilicum Oil (Dupont and Guerlain), 467.
Battery, Hot Fluid Primary, Description of
a, 371.
Bear’s Grease, Formula for, 60.
Beauty Merchant, A, 100a.
Beecham’s Pills, A Coroner on, 386a.
Bee’s Poison, Method of Extracting, 20a.
Bees Intoxicated by Honey (Williams), 163.
Beeswax, Adulterated, Prosecution at Bir¬
mingham, 484a.
— The Iodine Value of (Gayer), 308.
Begbie’s, Dr., Mixture, Composition of, 60.
— Dr., Pills, Formula for, 80.
Behring’s Antitoxic Serum in Diphtheria,
On the Effects of, 43.
Belgique, The Association G^rerale Phar-
maceutique de, 112.
Bell, R. H. — The Approaching Council Elec¬
tion, 427.
Belladonna and Zinc Oxide in Whooping
Cough, Formula for, 58.
— Dispensing Extract of, 504.
— Plasters (Hill), 75.
Bending Brass or Steel Tubes, 484, 504.
Benevolence, Remarks on Corporate, 137.
Benevolent Fund, An appeal for the (Mum-
bray), 78; (Kemp) 98; (Currie), (Smith),
(Moderate Man), 119; (Brown), (Roper),
137 ; (Rawling), 159 ; (Currie), (Smith),
(Kemp), (Bailey), (Thompson), 198;
(Editorial), 213 ; 256 ; (Riding), 263.
— Fund, Editorial Remarks on the, 181.
— Fund Festival Dinner, The, 108, 398, 429.
— Fund, Letter from the President on the,
180.
— Fund, List of Donations and Subscrip¬
tions in Aid of the, 451, 476, 491, 496.
— Fund, Manchester and District Assis¬
tants’ and Apprentices’ Special Appeal
in aid of the, 263, 286a, 386a, 504a.
— Fund, Manchester and District ; List of
Donations to the, 180, 244a, 286a, 326a,
366a, 428a.
• — Fund, Result of the Christmas Appeal
on behalf of the, 13, 20.
— Fund, The Nature and Work of the, 448.
Bent, Mr. Theodore, Death of, 422.
Benzacetin as an Anti Neuralgic ani Ano¬
dyne, 221.
Benzine, Sale of, 464.
Benzol and Benzine, to Distinguish (Lainer),
368.
INDEX.
Benzoline Explosion at Leeds', A, 286a.
Benzo-Naphthol and Bismuth Salicylate in
Infantile Diarrhoea, 405.
Berlin Medical Law and Chemists, 120a.
Best ant, F. R.— An Assistants’ Qualification
Wanted, 364.
Bevan, Edward. — The Brentford Glycerin
and Lime Juice Case, 463.
Biarritz, English Chemists in, at Christmas,
40a
Bicyclists and French Pharmacists, 205.
Bills, Parliamentary, still Waiting, 556.
— Position of Private Members’, 295.
— Progress of Parliamentary, 407.
Biologic rl Work, A Simple Microtome for
(Flatters), 485.
Birds, Gallinaceous, and Tuberculosis
(Lannelongue and Achard), 468.
Birkbeck Institution, Students’ Conversa¬
zione at the, 157.
Bismuth Benzoate (Rebhire), 82.
— Industry of Bolivia, 461.
— Iodogallate, Formula for the Preparation
of, 167.
— Tribromophenol as an Antiseptic (Cum-
ston), 196.
Bitters, Orange, Formula for, 9.
Blaud PilJ, The Composition of (Thompson),
83.
Bleaching Dyed Hair, 504.
Blue, The Difference Between Methyl Blue
and Methylene, 386.
Boa, Peter — Chloroform Water, 75.
B.ard of Trade, Sir Stafford Northcote and
the President’s Position, 494.
Boedecker’s Test for Albumin, 544.
Boilers, To Prevent Scale in, 472.
Bois- Raymond, Professor Emil du, Death
cf, 13.
Bolton’s Collodion Emulsion, Formula for,
484.
Bonuses, Distribution of, by Messrs. E. Cook
aEd Co., 504a.
Book on Bacteriology, 568.
— on Botanical Microscopy, 568.
Books of Reference, 524.
— on Brewing Beer and Stout, 346.
— on Domestic Medicine, 544.
Bcr jglyceride, Preparation of, 60 ; (Martin-
dale), 80 ; (Hick), 100 ; (Coull), (Borax),
(Free-Thinker), 119.
Bose, Prof. J. C. — The Physical Properties
of Electric Waves, 102.
Botanic Gardens of the World, 270, 507, 526.
Botanical Institute and Garden at Marburg,
The (Martindale), 174.
— Lectures before the Apothecaries’ Society,
by Prof. F. W. Oliver, 453, 522.
— Microscopy, Book on, 568.
— Society of Edinburgh, 281.
— Specimens for Students (Roberts), 59.
— Work in Jamaica and Aburi on the Gold
Coast, 384.
— Works, 80, 160.
Botany, Economic, in 1896, 17.
— H;nts on Field, 30.
— in 1896, 15.
• — Morphological, The Present Position of
(Scott), 34, 360, 478.
— of the Months, Notes on the, 10, 30, 50,
70, 90, 110, 179, 254, 276, 296, 336, 418,
534.
— On the Desirability of E Jablishing an
Institute for the Teaching of, in the
Royal Botanic Gardens (Maitindale),
183, 203; (Editorial Remarks), 214, 217.
— The Professorship of, in the University of
Eiinburgh, 295.
— The Teaching of Elementary, 409.
[July 3, 1897.
Bovril Stamnoids, 544a.
Boys, Professor C. V.— Capillary Ripples,
115.
Bradford and District Chemists’ Association,
96, 140a, 191, 219, 363.
Braithwaite, J. O. — A Sourious Balsam of
Tolu, 307.
— J. O. — Commercial Civet, 101.
Brandy Substitute, Formula for, 524.
Brewing Beer and Stout, Books on, 346.
Brighton Chemists and the P.A.T.A., 218,
454.
— Junior Association of Pharmacy,
56, 100a, 117, 136, 156, 193, 218, 240,
284, 302, 454.
Bristol Pharmaceutical Association, 97, 260,
401.
British Association for the Advancement of
Science, Botanical Section, 34, 360,
478.
— Association Meeting at Toronto, Arrange¬
ments for the, 133.
- — Institute of Public Health, 518.
— Manufactured Drugs, An Opening for, in
China, 426.
— Pharmaceutical Conference, Origin of
the, 140.
— Pharmacopoeia Preparations, The Specific
Gravities of the (Lunan), 219,
— Pharmacopoeia, The Ointments of the
(Lucas), 121.
— Pharmacopoeia, Explanatory Notes on
the, 10, 50, 70, 90, 110, 130, 150, 179,
254, 276, 296, 336, 356, 418, 474, 514,
534.
— Trade in Bulgaria, 58.
— Trade in Drugs and Chemicals during
1896, 568a.
— Trade, Obstacles to, 461.
— Trade with Maranham (Brazil), 461.
Bromide, Ethyl, and Suggestion in Hysterical
Aphonia (Arsslan), 426.
Bromides, Alkaline Iodides and (Knobloch),
460.
Bronzing Gun Barrels, Mixture for, 408.
Brown, A. J. — The Benevolent Fund, 137.
— J. F. — Liquor Bismuthi, 39.
Brown Varnish, Formula for, 80.
Buckley, J. A. — Help for Major Students,
139.
— J. A. — The Proposed New Bye-laws of
the Pharmaceutical Society, 264.
Bunsen Burner for Acetylene (Munby), 423,
469.
Barrage, J. H. — The Adhesive Discs of
Ercilla Spicata, 216.
Burroughs, Wellcome and Co.’s New Year’s
Dinner, 40a.
Bush (W. J.) and Co. — Elder Flower Oint¬
ment, 19.
Business Ways that are Dark ( Anti-Soft-
Sawder), 140 ; (A. J. P. S.), (Jones),
159; (Ellinor), 286.
Butt, Edward N. — On Chicle Gum, 328.
Buttercups, Poisoning by (Lancaster), 517.
Butyric Fermentation, 100.
Bye-Laws, Editorial Remarks on the Pro¬
posed New, 255, 277, 297.
— -Laws, the Proposed New, Comments on,
236, 256, (Austin), (Buckley), (Henry),
(Spero), 264 ; 278 ; (Henry), (K. K.), 285 ;
(Editorial), 297 ; (A Student of the
Pharmaceutical Society), 304 ; 318 ;
(Turnbull), (A Member of the Pharma¬
ceutical Society), (T. T.), 325 ; (Russell),
343; 358, 362; (Associate), 364; 380, 382,
383; (Rawling), 384; 401, 403, 404,
424 ; (Vizer), 428 ; 437, 454 ; (St. Cyr) .
483.
July 3, 1897.]
c
Cabot Tower at Bristol, The Proposed, 379.
Cacodyl Compounds for Therapeutic Use,
221.
Cade, Oil of, Acetone Collodium and
(Gaucher), 314,
Caffeine, Homologues of, 21.
— load, 158.
Calamines, Improved Formula for Lini-
mentum (Skinner), 513.
Calcium Carbide, Reduction by (Warren),
81.
— Carbide, The Danger of, 154.
— Carbide, The Storage and Conveyance of,
186, 206 ; (Order), 212 ; (Memo), 234 ;
318.
— Oleate, The Dispensing of, 326.
— Oxalate, Function of (Kraus), 370.
Calendar of the Pharmaceutical Society of
Ireland, Notes on the, 132.
Cali=aya Bark, Alkaloids of, 504.
Cambridge Pharmaceutical Association,
220, 281, 346a.
Camphor, Cultivation of Chinese, 426.
— Exports of from Tamsui during 1895, 426.
— Powder, Note on Permanent, 355.
— The Production of in China (Henry), 201.
Camphoronic Acid, The Synthesis of (Per¬
kin), 280.
Campkin, A S., and the Manchester Unity
at Douglas, Isle of Man, 544a.
Canadian Apatite, 502.
Canary Islands, English Trade in Drugs with
the, 38.
Capillary Ripples (Boys), 115,
Capping Material, New, 74.
Capsicum Fruits, How to Cut Sections of
(Flatters), 507.
Capsule, The History of the (Alpers), 25, 66.
Capsules, Membranous, 544a.
Caramel in Fluid Extracts, 167.
Carbide, Iron (Moissan), 367.
Carbolic Acid Pastilles, Formula for (3alz-
mann), 314.
— Acid Scheduled as a Prison in Ireland,
558.
— Acid, The Use of, for Tempering Steel
Tools, 183.
Caibon and Hydrogen, Union of (Bone and
Jerdan), 287.
— Dioxide in Clothes (Wolpert), 368.
— On the Atomic Weight of (Scott), 280.
Carbonate, Oxidation of Ferrous, 464.
Cardell, R T. — The Preliminary Exanr'na-
tion, 140.
Carpaine (Van Rijn), 466.
Casella, Louis Pascal, Death of, 379.
Cash Book, A Useful, 503.
Cassias, Parple of (Antony and Lucchesi),
368.
Casson, Frank— Old Pharmacy, 87.
Castoreum da Gardon (Gal), 161.
Catgut, Sterilisation of (Larrabee), 162.
Cement to Fasten Metal to Glass, Formula
for, 246.
Cereal Crops, The Diseases of (Oliver), 522.
Cerium Salts as Antiseptics, 363.
Certificates, The Victoria Pharmacy Board
and the Qaestion of Reciprocity in, 449.
Charity, Art, and Humour, 263.
Chattaway, F. D., and Stephens, H. P. — The
Hydrolysis of Perthioc.) anic Acid, 320.
Cheavin’s Microbe-Proof Filters, 196.
Check Tills — A Want (Inquirer), 138 ;
(Cook), (Francis and Co.), 160 ; (Hollo¬
way), 199 ; (Hogg), (Bartleet), 224.
Chelidonine Salts as Anodynes, 196.
INDEX.
Chelidonium Majus, Extract of, in Cancerous
Tumours (Denisenko), 86.
Chemical and Bacteriological Examination
of Milk (Davies), 302.
— Arts, Sixty Years’ Progress in Chemistry
and the (Thorpe), 511.
— Changes in Crude Drugs (Dieterich), 529.
— Equations, On, 90.
— Industry, The Society of, Invitation to
visit Nottingham, 538.
— Laboratory in Pharmacy, The (Mayer), 27.
— Reagents, Living Tissues as (Wild), 125.
— Society, 94, 134, 187, 238, 280; (Annual
Dinner), 299, 300; 320, 400, 423, 480,
521.
Chemist, Death of a, from Exposure, 20a.
— “ Poor,” Editorial Remarks on Considera¬
tion for the, 277.
— Prosecution of a, under the Medicine
Stamp Act at Lambeth, 136.
— The Affairs of a North Devon, 60a.
— The True Pharmaceutical, 450.
Chemistry, Ancient and Modern (Kelly), 311,
423.
— and the Chemical Arts, Sixty Years’
Progress in (Thorpe), 511.
— Higher Research in, 113.
— in 1896, 14.
— of Douradinha (Peckholt), 369.
— of Woolfat (Darmstaedter and Lifschlitz),
369.
Chemists and Company Legislation (Why-
sal)), 38.
— and Druggists’ Society of Ireland (North
Branch), 404.
Chemists’ and “ Wea'her,” 100a.
— Assistants’ Association, 77, 95, 117, 137,
155, 188, 218, 239, 258 (Removal to New
Premises), 279, 283, 303, 322, 340, 408a,
423
Chemists’ Assistants’ Association, Some
Suggested Improvements in the Rules of
the (Tasker), 155.
— Ball, The, 80a.
— Club (London), 100a, 120a, 286a, 422.
— Exhibition for 1897, The, 450.
— Federation (Foulston), 39 ; (Cooper), 59,
(Plymouthian), 79; (Park), 99.
— Holidays (A.P.S.), 385.
— Protective Association, The Need of a
(Higgs), 462.
Chemists’ Qualification, The Court
Journal and, 73.
— Wine Licences, 464d!.
— Remuneration, Editoral Remarks od, 297.
Chemists who are Sub-Postmasters,
Combination of, 497.
Chicle Gathering in Mexico, 568a.
— Gam, On (Butt), 328.
China, Diet and Medicine in, 113.
Chinese Camphor, Cultivation of, 426.
— Ideas of Chemistry, Anatomy, and
Physiology, 113.
— Opium, The Returns of Duty and Likin
on, 384.
— Soap Industry, The, 568a.
Chinosol Preparations, 524a.
Chloride, Mercuric, as a Remedy for
Potato Disease, 417.
Chlorine, The Behaviour of Under the
Influence of Electricity and in Sunlight
(Shenstone), 94.
— Water, Extemporaneous Preparation of
(Griggl), 513.
Chloroform for the Greeks from Forshaw
and Snow, 428a.
— Presence of Water and of Alcohol in
(Behai and Frat^is) 465.
— Water (Boa), 75.
Supplement to
Pharmaceutical Journal.
Chlcros Disinfectant, 524a.
Chlor-Zinc-Iodine Solution, Schulze’s, 366.
Chouan Seed, and Autour Bark (Pharmacist),
384 ; (Ashton), 408.
Chrysoidin and Cholera (Blachstein), 508.
Cinchona Bark, The Manufacture of Quinine
from, 568a.
Cinchonine into Cinchonidine, The Alleged
Conversion of (Paul and Cownley), 141 ;
(Shaw), 199, 286.
Cinematographs and the Fire in Paris, 473.
Cineraria, Origin of the Garden, 340.
Citrates of Phenetidine (Heyden), 24.
Citric Acid, Synthesis of (Laurence), 466.
City and Guilds of London Institute, 92.
Civet, Commercial (Braithwaite), 101.
Clague, T. M. — A Correction, 100.
— T. M.— Proposed Association at New-
castle-on-Tyne, 80.
— T. M — The Part of Combination in
Modern Pharmaceutical Life, 381.
Clove Pink Perfume, Formula for, 460.
Clower, John — The Proprietary Articles
Trade Association, 344.
Club, A London Residential, 486.
Coal Box, A Novel, 74.
Coal-Tar Dyes and Digestion (Weber), 82.
Cobalt, Cobaltites, etc., The Oxides of
(McConnell and Hanes), 238.
Cobwebs and Wine, 371.
Cocaine, Difficulty in Dispensing (Jenkins),
385.
— Sale of, 120.
Coca-Kola Wine (Potter and Clarke), 197.
Coca, Miscible Fluid Extract of, To Prepare,
604.
— Wine and its Dangers, Remarks on, 133.
— Wine of Commerce, The (Barclay), 341.
Coccospheres and Rhabdospheres, The Form¬
ation of (Murray), 340.
Coccus Rusci.the Parasite of the Fig, 502.
Cockshott, W. A. — John Dalton and the
Atomic Theory, 61.
Cod- Liver Oil, Formula for Emulsion of, 484.
— -Liver Oil with Hypophosphites, 197.
Coffee, Dr. Dabb’s P.B. Essence of, 464a.
Coils for Evaporation, On the Use of S;eam
(Warden), 307.
Colchici, Vinum, Note on (CowLy), 173.
College of Pharmacy, A Royal (Gieenisb),
408 ; (Forshaw), (Jesper), (Rogerson
and Son), 427 ; (Fyton), 462 ; (A Young
Chemist), 483; (Fyton), 542.
Collie, Dr. — The Production of Pyridine
Derivatives from EthylicqS-Amido Cro*
tonate, 187.
Collodion Emulsion, Bolton’s, Formula for,
484.
— Preparation for Photography, 60.
Colour and Perfume Ointment, To, 366.
— of Alcohols Compared with Water
(Spring), 417.
— Photography, The Process of, 111, 132,
172; (Wood), 187, 473.
Colours for Show Bottles, Formula for, 306.
Combination in Modern Pharmaceutical
Life, The Part of (Clague), 381.
Commemoration Bouquet, 504 b.
— Festivities, Arrangements for the, 537.
Commercial Civet (Brathwaite), 101.
— Gingers and Essence of Ginger (Glass),
245.
— Interests, Professional and, Editorial Re¬
marks on, 495 ; (Glyn-Jones), 503.
— Varieties of Fennel and Their Essential
Oils, The (Umney), 225, 232.
Companies Bill, The, 109, 154, 212, 242, 275,
518.
C ompany Pharmacy, 20a
Supplement to
Pharmaceutical Journal.
Compliant, A Personal (Onion), 189;
(Thompson), 160.
Composition, The Art of Literary (Ince),
292.
Compounders of Spirits, Special Licence
Required for, 421.
Compressed Drugs, 74.
Condensers, Aluminium (Norton), 290.
— and X Ray Tubes, (Norton and Lawrence),
290.
Conference Blue List, The, 487, 496.
— British Pharmaceutical, Arrangements for
the 1897 Meeting, 13, 239, 487, 519, 566.
— British Pharmaceutical, Subjects for
Papers, 487.
— British Pharmaceutical, The Oiigin of the,
140.
Conroy, Michael — Balsam of Copaiba, 219,
Consideration for the “ Poor” Chemist,
Editorial Remarks on, 277.
Consular and Diplomatic Reports, Distribu¬
tion of, 8.
— Reports, Extracts from, 38, 58, 158, 384,
406, 426, 461, 502, 568a.
Cook, W. R.— Check Tills, 160.
Cooper, G-. T. — Chemists’ Federation, 59.
Copaiba Balsam, Maturin (Dietze), 369.
-- Balsam of (Conroy), 219.
— Poisoning (Thompson), 369.
Copper in Oysters (Lowe and Haedman), 162;
(Lowe), 493.
Copyright (Amendment) Bill, The, 461, 518.
Corals and Coral Islands (Swainson), 95.
Corks, Disposal of Old Clean, 200.
Corrections, 50, 60, 80, 100, 200, 386, 428,
484.
Corydaline (Dobbie and Marsden), 465.
Cotton, Manufacture and Examination of
Iodised (Soulard), 417.
Coull, George — A Disclaimer, 79.
— George — A Panegyric — The Other Side,
119.
— George — Ferrous Phosphate, 199.
— George — Nitrous Acid in AquaDestillata,
199.
— George — The Latin of Phrmacy, 272
291.
Council Election, The Forthcoming (Gost-
ling), 304 ; (Keen), 325 ; (Storrar), 345 ;
(Maben), 364; (Norfolkensis), 385;
(Editorial Remarks), 397 ; (Bell),
(Johnson), (Musca), 427.
— Election, The Result of the (Editorial
Remarks), 447, 475 ; (Atkinson), (Hy-
slop), 483; (Sharman), 502; (Glyn-
Jones), (Hinde), 503; (Hyslop), (Atkin¬
son), 523; (Glyn-Jones),(An Old Pharma¬
cist), (Young), 542 ; (Atkinson), 568.
— Meetings, Editorial Remarks on the, 51,
111, 213, 317, 397, 432, 495.
— The Work of the, in 1896, 1.
Counter Prescribing, On (Barrass), 243.
Couple, Improved Zinc-Copper (Stock), 290.
Cowley, R. C. — Analysis of Fatty Oils, 239,
329.
— R. C. — Note on Vinum Colchici, 173.
— *R. C.— Peach Kernel Oil in Olive Oil, 305.
Cowoley, A. J., and Paul, Dr. B. H. — The
Alleged Conversion of Cinchonine into
Cinchonidine, 141.
Crabs. Idiosyncrasy Against (Ki'rschberg),
472.
Crayons, Mentholated, Formula for, 167.
Cream or Cod-Liver Oil, 544a.
Creosote in the Treatment of Pleuro-Peri-
toneal Tuberculosis in Children (Thoma),
221.
— The Dose of (Harvey), 325.
Crepe Bandages, 5045,
INDEX.
Cricket Club for Ladies, A Pharmaceutical
(Emery), 427.
— - Pharmaceutical, 544 d.
Crookes’ Tubes, The, 122.
Crookes, William — Diamonds, 538.
Cross, W. Gowen — The Journal and its
Students’ Page, 99.
Cryptogams, Some Notes on 276, 296, 356,
418.
Crystallisation of Stannous Iodide, The
Apparent Action of Light in Inducing
(Warden), 61.
— of Super-Saturated Solutions (Ostwald),
465.
Crystallography (Morgan), 146.
Cultural Evolution of Cyclamen Latifolium
Sibtb, 340.
Cumarin, Purification of (Claassen), 161.
Currie, Archibald- — Wanted, An Assistants’
Qualification, 427.
— W. L. — The Benevolent Fund, 119, 198.
Cyclists, The Dietary of, 517.
Cymralis Water, 197.
Cytisine in Medicine, Value of (Plugge), 472.
D
Dalton, John, and the Atomic Theory
(Cockshott), 61.
Darwin andWeismann, Editorial Remarks on
an Anticipation of, 357.
Davies, Herbert E. — Chemical and B rcterio-
logical Examination of Milk, 302.
Davy, Humphry : Poet and Philosopher
(Thorpe), 41.
Death Certificate Signed by a Chemist, A,
524a.
— Roll of the Year 1896, 7.
Deaths Caused by Poisons and Poisonous
Vapours during 1895, 477.
— from Misadventure, 92.
Deer Suet, Formula for, 60.
Dendrobium Brymerianum, A CaS3 of
Synanthy in (Reynolds), 319.
Dentists Act, Proceedings under the (Edin¬
burgh), 541.
— Act, The Interpretation of the, 538.
Developer, A Novel Pyro, 4645.
— Formula for Tondeur, 544.
— Hydrokinone and Pyrogallol, Formula for,
408.
— Single Solution, Formula for, 408.
Development of Fungi, Influence of External
Conditions on the (Lendner), 468.
Devonshire Cream and Malt Extract, 263.
— Medical Officer’s Salary, A, 366a.
Dewar, Prof. — L’quid Air as an Agent of
Research, 400, 423, 456.
— Prof. — The Properties of L’quid Oxygen,
94.
Diamonds (Crookes), 538.
Diastase, The Action of Light on, and its
B'ological Significance (Green), 528.
— in Fungi, Formation of (Pfeifer), 290.
— The Action of, on Starch (Ling and
Baker), 94.
Diatoms, Mountants for, 80.
— Reproduction of Marine (Murray), 163.
Di8t and Medicine in China, 113.
Dietary of Cyclists, The, 517.
Dietericb, Karl — Chemical Changes in
Crude Drugs, 529.
Digestion (Larkin), 96.
Digitalis, Collection of, 80.
Diphosphide, Silver (Granger), 467.
Diphtheria Antitoxin, Electrolytic (Smir-
now), 368.
— Antitoxin, The Use of, 476.
Diseases of Cereal Crops, The (Oliver), 522.
July 3, 1897.
Disinfection with Formic Aldehyde (Blyth),
469.
Dispensary, Visit to a Parish, 175.
Dispenser, Degrading the (Ad Uirumque
Paratus), 344.
— Sweating the (Anti-Sweater), 138 ; (Dis¬
penser), 224 ; (Blad R. O’Lard), (Anti-
Sweater), 263, 264 ; (A.P.S.), 285 ;
(Dispenser), 305 ; (Anti-Sweater), 384 ;
(Dispenser), 428.
Dispensers, Army Compounders as Public,
Editorial Remarks on, 131.
— Public Service (A Fifteen Years’ Dis¬
penser), 325.
— Remarks on the Capacity of, 93.
Disp-nsersbips in the Naval Medical Service,
215 ; (Videre est Credere), 365.
Dispensing Balance, Novel, 8.
— Cocaine, Difficulty in (Jenkins), 385.
— Difficulty (Welsh), 300.
— Emulsions, On, 130, 150, 178.
• — Notes, More (Wyatt), 464c.
— Queries, 286, 326, 346, 366.
— Sixty Years Ago, Notes on (Proctor), 553.
Doctor and Dentist in the Welsh Chubut
Settlement, 568a.
Doctors and Medicine-men (Wilson), 135.
“ Dodges in the Drug Trade,” Cassell’s Satur¬
day Journal and, 237.
Dctt, D. B. — Note on the Drying of
Alkaloids and their Salts, 21.
Douglas Mixture for Fowls, Formula for,
408.
Douradinha, Chemistry of (Peckholt), 369.
Drapers’ Company and the Radcliffe Library
at Oxford, 537.
Dressing for Skin Diseases, Gelante A New
(Unna), 417.
Drosera Growing, and Is Drosera an
Annual? 275.
Druce, Mr. G. C., and the Oxford City
Council, 450.
Drug and Chemical Trade of Japan, Re¬
marks on the, 153.
“Druggists’ Misfortune, A,” at Bourne¬
mouth, 183.
Drags, A Grocer and the Sale of, 366a.
— Chemical Changes in Crude (Dietericb),
5*9.
— Chemicals and Colours (Servia), 461.
— Euglish Trade in, with the Canary
Islands, 38.
— in China, An Opening for British Manu¬
factured, 426.
— Notes on the Use3 of, 88.
— Therapeutic Activity of (La Wall), 288.
— The Samples o% Examined during 1895,
257.
Drying-Box for Pills, etc., A (Warden), 245.
— of Alkaloids and their Salts, Nate on the
(Dott), 21,
Dual Function of the Pharmaceutical Society,
Editorial Remarks on the, 419.
Dubosiue Sulphate iu Paralysis Agitans
(Mendell and Francotte), 118.
Duelling in German Universities, Remarks
on, 133.
Dumfries Chemists and the P.A.T.A., 60a;
(Sutherland), 80.
Dunlop, T. — Guaiacum Resin, 139.
Durrant, George R.— Insect Powders of
Commerce, 505.
Dyer, E. H. — The Journal and its Students’
Paze, 99.
Dyes, German Profits in the Manufactu-e
of, 449.
Dymond, T. S., and Hughes, F. — The Oxida¬
tion of Sulphurous Acid by Potassium
Permanganate, 187.
July 3, 1897.
Dysentery, etc., in Lambs, Balls for, 504.
E
E ‘,rly Closing Bills, The, 98, 109, 212, 275,
'376.
Earth as an Abode Fitted for Life, The Age
of the (Kelvin), 517.
Earwigs, Compound to Catch, 275, 335, 366.
E zjma Caused by Hyacinths, 115.
Edinburgh Chemists’ Assistants’ and Appren¬
tices’ Association, 75, 117, 156, 2i8, 210,
284, 300, 380, 520, 544a.
— District Chemists’ Golf Club, 240, 262,
366a, 408&, 484a, 504a.
— District Chemists’ Trade Association, 97,
135, 302, 497, 520, 539.
— Pharmacy Athletic Club, 20a, 464a!, 484a,
504a.
— Pharmacy Students’ Supper, 221.
— The Professorship of Botany in the Uni¬
versity of, 295.
Education, Editorial Remarks on Technical,
337.
— of Pharmacists, Remarks on the Earlier,
278.
— The Parliamentary Committee of Council
on, 262, 494.
Egg Shampoo, Formula for, 544.
Elder Flower Ointment (Bush and Co ), 19.
Electric Telegraph “ Jubilee,” Ad, 559.
— Wave Apparatus (Bose), 81.
— Waves, The Physical Properties of (Bose),
102.
Electrical Currents in the Human Body,
Prof. Horsley’s Lecture on, 184.
Electricity, Remarks on “Penny in the
Slot,” 152.
— The Source of, in Radiography, 22.
— The Use of the Nile as a Source of, 339.
Electrification of Air by Rontgen Rays (Kel¬
vin), 32.
Elementary Botany, Some General Im¬
pressions on the Teaching of, 409.
Elephant-*, The Poisoning of, 421.
Eilinor, G. — Business Ways that are Dark,
286.
Embrocation, Formula for White, 346.
— for Whooping Cough, Formula for, 9.
Emery, Eva — A Pharmaceutical Cricket
Club for Ladies, 427.
Emulsifying Agents, Various, On Dispensing
Emulsions, 130, 150, 178.
Emulsion, Bolton’s Collodion, Formula for,
484.
— of Cod- liver Oil, Formula for, 484.
— Petroleum, 484.
Emulsions, On Dispensing, 130, 150, 178.
Enamel Varnishes, Formulas for, 464.
Era Course in Pharmacy, The 568d.
Ercilla Spicata, The Adhesive Discs of
(Burrage), 216.
Ergotinol, The Method of Obtaining, 287.
Esbach’s Reagent, 326.
Essence of Lemon, The Keeping Qualities of
(Typke and King), 120; (Kobins), 159.
Essences of Soap, Formulae for, 460.
Ether Drinking in Derry, 80a.
Ethics, A School of, for London, 517.
Ethyl Alcohol, Acetaldehyde, and Acetic
Acid (Tayler), 300.
— Bromide and Suggestion in Hysterical
Aphonia (Arsslan), 426.
E hylene, Action of Nickel upon (3abatier
and Senderens), 319.
Eucaine as an Anaesthetic (Horne and Years-
ley ), 82.
— Ointment Formula, 417,
INDEX.
Evans, E. J.— Ferrous Phosphate, 141.
— J. J. O. — “Potato Drops and Green Mal¬
let,” 385.
Evaporation, On the Use of Steam Coils for
(Warden), 307.
Evolution of Green Algae (Chodat), 468.
Examination Syllabus, The Minor (Audi
Alteram Partem), 100.
Examinations in 1896, 3.
Examiners in the Education Department,
Captains Norton, M.P., and, 461.
— Remarks on Complaints against, 92.
Exchange, A Scheme of (Macpherson), 135.
Excise Lic.nces Bill, The, 518.
Exeter Association of Chemists and Drug¬
gists, 55, 116,
— Dispensary (Annual Meeting), 190.
— Technical College Prizes for Pharmacists,
299.
Explosion in a Chemist’s Shop at Hull,464i.
Explosions, Products of Acetylene (Bone and
Cain), 287.
Extract of Vegetables, An, 57.
F
Face Lotion, Startin’s Formula for, 326.
Farr, E. H. — The Proposed New Bye-laws
of the Pharmaceutical Society, 264.
— E. H., and Wright, R. — The Determina¬
tion of Alkaloids, Notes on Some of the
Pharmacopoeial Processes, 202.
Fatty Oils, The Analysis of (Cowley), 239,
329.
Features of Progress, Editorial Remarks on
Some, 557.
February, The Flowers of, 110, 179.
Federation, Chemists’ (Foulston), 39 ;
(Cooper), 59 ; (Plymouthian), 79.
Fennel and Their Essential Oils, The Com¬
mercial Varieties of (Umney), 225, 232.
Ferment from Yeast (Buchner), 288.
Ferns, etc., Books on, 40.
— (Wood), 135.
Ferri et Quininm Citras and Potassii Citras,
Dispensing Experience with (Wokes),
321 ; (Stratton), 344.
Ferric Salicylate, The Colour of, 200.
Ferridcyanide Reducer, The Action of, 244.
Ferrous Carbonate, Oxidation of, 464.
— Phosphate (Evans), 141; (Coull), 199.
Fertilisation and Germination of Loran-
thacere (Keeble), 83.
— in the Gymnosperms (Ikeno and Hirase),
162.
Fibre, The Cultivation of Rhea (Playfair),
376.
Field, Admiral, and “ Nelson’s Enchantress,”
186.
— Botany, Hints on, 30.
F re at a London Drug Mill, 60a,
— at the Schering Chemical Works, 524a,
544a.
Fire-Resisting Decorations, 518.
Fires at Chemists’ Shops, 100a, 326a, 386a,
428a.
Fireproof Paint, Formula for, 266.
Fireproofing Timber, Method of, 266.
Fish, The Composition of Cooked (Williams),
320.
Fishes, Remarks on the Existence of Memory
in, 93.
Fixing Bath, Acid, 244,
— Solution, New, for Vegetable Tissues, 374.
Flask, A New Weighing (Heath), 290.
Flatters, Abraham — A Simple Microtome for
Biological Work, 485.
— Abraham — How to Cut Sections of
Capsicum Fruits, 507.
[Supplement to
Phabmaceutical Journal.
Floral Pomade, Formula for, 306.
Florida Water, Formula for, 530.
Flower Cement, Preparation of, 464.
Flowers Attract Insects, How (Plateau), 163.
— Extracting the Perfume of (Pussy), 369.
— of (Enothera, Opening of the (Planchon),
468.
— of the Months, The, 10, 30; (Holmes),
(Pollard), 39; 50, 70, 90,110, 179,254,276,
296, 336, 418, 534.
Fluorine, Liquefied (Dewar), 496.
— The Isolation of (Moissan), 499.
Fly-Papers, “ Flyodoomo,” in Court, 20a.
Food and Drugs Act, A Bill to Amend the
S de of, 97, 98 ; (Editorial Remarks),
235 ; 275, 324, 461, 473, 494, 556.
— and Drugs Act at Nottingham, Magis¬
trates and Doctors and the Sale of, 536.
— and Drags Act in Yorkshire, The 346a.
— and Drugs Act, Proceedings Under the
(Nitrous Echer), 56 ; (Rhubarb), 57 ;
(Sugar), 80a ; (Arsenical Soap), 77,
120a; (Nitrous Ether), (Salicylic Acid),
120a ; (Milk of Sulphur), 118 ; (Gly¬
cerin), 194 ; (Glycerin and Lime Juice),
253, 274, 298, 303, 363; (Rhubarb), 366a;
(Arsenical Soap), 415 ; (Glycerin and
Lime Juice), 416; (Beeswax), 484a;
(Laudanum), 504a; (Olive Oil), 524a;
(Nitrous Ether), 540.
— and Drugs Act, The Sale of (Warreil),
264.
— and Drugs Millennium, A, 257.
— and Drugs, the Purity of, Editorial
Remarks on, 91, 182.
— Materials of Algse (Moliscb), 289.
— Products Adulteration, 98.
— Products (Liverseege), 55.
— Taken ? When is (Inquirer), 263.
Foreign and Colonial Trade of the United
Kingdom, Remarks on the, 153.
Forfarshire District Chemists’ Association,
382, 403.
Formalin, The Use of, in Photography, 473. '
Formic Aldehyde, Disinfection with (Blyth),
469.
Formulae, Selected Practical, 9.
Forshaw, T. Garratt — A Royal College of
Pharmacy, 427.
Fossil Antlers (Lowe), 115.
— Bacteria (Renault), 162.
— Plants (Seward), 127.
Foster, Sir Walter, M.P., Award of the Geld
Medal of the British Medical Associa¬
tion to, 378.
Foulston, G. R. — Chemists’ Federation, 39.
Francis and Co. — Check Tills, 160.
Freezing Mixture, Preparation of a, 396.
Freezing-Point Curves of Alloys Containing
Zinc, On the (Heycock and Neville),
238.
French Academy of Sciences, Gift by Mr.
H. Wilde to the, 319.
— Oils, The Origin of so-called, 406.
— Pharmacists and Bicyclists, 20c.
— Polish, Formula for, 80.
Fresenius, Professor Karl Remigius, Death
of, 538.
Fruit and Seed of Viscum (Gjokie), 289.
— Preservation, The Kent County Council
and, 358.
Fruits, Rotting of (Wehmer), 163.
Fumitory in Skin Diseases, 196.
Fungi, Acid-loving (Wehmer), 289.
— Formation of Diastase in (Pfeffer), 290.
— Influence of External Conditions on the
Development of (Lendner), 468.
— Parasymbiosis of (Zopf), 468.
Furniture Cream, Red, Formula for, 20.
Supplement to
Pharmaceutical Journal.
Fusible Alloys, Formu’® for, 464.
G
Galiicaceous Birds and Tuberculosis (Lanne-
longue and Achard), 468.
Gamble, F. W. — Antitoxins, 340.
Gamboge, Composition of (Sassarini), 288.
Gardner, W. — Modern Alchemy, 191.
Gartb, Sir Samuel, M.D., The Career of, 348.
Gas Companies of the United Kingdom,
The, 113.
— for Domestic Lighting, The Use of
(Lewes), 65.
— for Lethal Chambers, 386.
Gases as Heat Conductors (Villari), 469.
Gelante, A New Dressing for Skin Diseases
(Unna), 417.
Gelatin Capsules (Alpers), 25, 66.
■ — Formula for Agar-Agar, 396.
— To Coat Horse-balls with, 464.
Gelatin isation of Tincture of Kino, 464.
Gelsemic Acid (Coblentz), 467.
Gelsemium, Active Piinciples in (Sayre), 467.
- — Composition of (Sayre), 83.
Geologists’ Association of London, Thp, 279.
German Competition with British Goods in
the U.S.A., 568®.
— Ph. D. Degree, 464.
— Thermometers, Remarks on, 279.
Germination of Barley (Gifiss), 163 ; (Day),
290.
Gibson, M. — Solubility cf Iodine in Cod-
Liver Oil, 199, 265.
Giles, R. W. — Reminiscences of the School
of Pharmacy (The Session of 1847 8),
506.
Gin, An Analysis of Trade, 426.
Ginger Beer, Formula for, 266.
— Spent, Mr. T. P. Blunt on, 20 o.
— Wine, Formula for Essence for, 483.
Gingers and Essence of Ginger, Commercial
(Glass), 245.
Ginkgo Tree, The (Smith), 137.
Glasgow and West cf Scotland Pharma¬
ceutical Association, 55, 96, 284, 301,
323.
— Apothecaries’ Company, Presentation to
Mr. A. M. McAdam, 408 b.
— Chemists and the P.A.T.A., 60a.
— Conference, Arrangements for the, 374,
378.
— Chair of Materia Medica in the University
of, Editorial Remarks on the 558.
Glass, Formula for Solution to Silver, 544.
Glass, W. S. — Commercial Gingers and
Essence of Ginger, 245.
— W. S. — The Social Status of the Pharma¬
cist, 543.
— W. S.— Wanted, An Assistant’s Qualifica¬
tion, 407.
Glaze for Cookery, 408.
Glycerin and Cucumber, Formula for, 464.
— and Lime Juice, The Sale of, 253, 274,
278; (Hyslop), 286 ; 298, 303, 363,416,
421; (Bevan), 463; (Webter), 483;
(Strickland), 502.
— Cream for Chapped Hands, Formula for,
244.
-T- Formula for Rial Lime Juice and, 386.
— Jelly, Formula for, 40.
— The Sale of Adulterated, at Birmingham,
194,
Glycerinum Amyli, Note on (Pearson), 201.
Glycerophosphates, A Simple Method of Pre¬
paring (Delage), 413.
Glycin, The Formation of, 244.
Glyn- Jones, W. S. — The Council Election
and the P.A.T.A., 503, 542.
INDEX-
Glyn- Jones, W. S.— The Proprietary Articles
Trade Association, 23.
— W. S. — The Proprietary Articles Trade
Association, and Local Pharmaceutical
Associations, 350.
Gold from Silver (Emmens), 100a.
Goldby, F. — The Sale cf Morphine, 462.
Goods Act, Proceedings under the Sale of
(Kingston), 415, 420.
Gostling, T. P. — The Forthcoming Council
Election, 304.
Gout, The Treatment of (Ewart), 28.
Government Stamp on Jugs, Marking the,
366.
Graft, Influence of the Stock on the
(Riviere and Bailbache), 290.
Graph, Formula for Composition for, 346.
Gravimetric Determination of Invert Sugar,
484.
Greece, Pharmaceutical and Medical Assist¬
ance for the War in, 398.
Green, Prof. J. Reynolds — On the Action of
Light on Diastase and its Biological
Significance, 528.
Greenish, Thomas — A Royal College of
Pharmacy, 408.
Grocers and the P.A.T.A., 516, 558.
Group Reagent, Sodium Peroxide as a
(Parr), 367.
Groves, T. B.— Reminiscences of the School
of Pharmacy (The Session of 1850-51),
563.
— T. B. — Solubility of Iodine in Cod-liver
OJ, 223.
Guaiacol Phosphite, Preparation of (Bal¬
lard), 368.
— Valerianate (Vogt), 425.
Guaiacum Resin (Doebner and Lfijker),
369.
— Resin, Note on (Smith), 101 ; (Dunlop),
139.
Gun Barrels, Mixture for Bronzing, 408.
Guyer, R. G. — Solubility of Iodine in Cod-
Liver Oil, 223.
— R. G. — The Iodine Value of Beeswax,
308.
Gymnosperms, Fertilisation in the (Ikeno
and Kirace), 162.
H
Hsematogen (Hertel), 167.
Haemorrhoids, Formula for Remedies for, 326.
Hager, Dr. Hans Hermann Julius, Death of,
112.
Hair Curling Fluid, Formula for, 266.
— Dark, to tu^n Yellow, 100.
— To Bleach Dyed, 504.
— Wash, Formula for Cheap, 464.
— Wash, Mercury in, 366.
— Wa -h with Bay Rum and Yolk of Egg,
Formula for, 266.
Hairs which are not Trichomes (Tieghem),
371.
Half-Holiday Bill, 407.
Halifax and District Chemists’ Association,
160a, 424.
Hampstead’s Mineral Springs, 20a, 73.
Hanbury, Mr. Thomas, Presentation of a
Drinking Fountain to the Town of Men¬
tone by, 339,
Hanes, E. S., and McConnell, A. H.— The
Oxides of Cobalt, etc., 238.
Harvey, S. — Arsenical Soaps, 462.
— Dr. William, The Life and Work of
(Summers), 155.
— W. — The Dose of Creosote, 325.
Healy, Mr. Timothy, and Carbide o' Cal¬
cium, 295.
[July 3, 1897.
Heat Conductors, Gases as (Villari), 469.
Helianthus Annus, Extract of, in Malaria
(Moncorvo), 58.
Heliotrope Perfume, Formula for, 460.
— White, Formula for, 306.
He’iotropinefrom Saffrol, 544.
Heliotropism, Positive and Negative (Olt-
manns), 467.
Henry, Augustine — The Production of
Camphor in China, 201.
— Claude F. — The Proposed New Bye-laws
of the Pharmaceutical Society, 264, 285.
Herbarium Prize, Competition for, 496.
— Specimens, Formula for the Preservation
of, 160.
Hewlett and Son’s Staff Outine, 544a.
Heycock, C. T., and Neville, F. H. — On the
Freezing-point Curves of Alloys Con¬
taining Zinc, 238.
— C. T.— X Ray Photos of the Solid
Alloys, 423.
Hick, John — A Panegyric, 100.
Hick man, F. S. — The Journal and its Students
Page, 120.
Higgs, Alfred — The Need of a Chemists’
Protective Association, 462.
Highly- purified Substances, Studies of the
Properties of (Shenstone), 94.
Hill, J. R.— Belladonna Plasters, 75.
Hills, Mr. Walter, at Oxford, 402.
— W. — The Pharmaceutical Society’s
Benevolent Fund, 180.
Hinde, A; H. — The Council Election, 503.
Histology of the Vegetable Tissue Systems
(Morison), 470.
Hogg, Samuel — On Check Tills, 224.
Holiday Science (Scotch Chemist), 224.
Holloway, E. A. — On Check Tills, 199.
Holmes, E.M. — The Cultivation of Sumbul
in England, 347.
— W. M. — The Flowers of January, 39.
Hdccaine, The Composition of, 368.
Holyrood Table Water, 13.
HolzinoJ, Composition of, 363.
Homing Instinct in Animals, The (Weii),
335.
Homologues of Caffeine, 21.
Homology of the Pollen and Ovule (Molliard),
83.
Honey, Bees Intoxicated by (Williams), 163.
— Poisonous (Gerpen), 289.
Honeycomb, A Vegetable, 20c.
Honours, The Jubilee List of, 559.
Hooper, Mr. David, Appointment of, as
Curator to the Indian Museum, Calcutta,
386a.
Hop Ale Syrup for Ae:ati:n, Formula for,
200.
— Bitters, Formula for, 160.
Horse-balls, To Coat, with Gelatin, 464.
Hoseason, J. H. — Alkaloids, 96.
Hot Fluid Primary Battery, Description of
a, 371.
Hovenden, S. C. — Artificial Light, 155.
Howard, Mr. David, on the Merchandise
M-.rks Act, 1887, 343.
Hughes, F., and Dymond, T. S.— The Oxida¬
tion of Sulphurous Acid by Potassium
Permanganate, 187.
Hull Chemists and the P.A.T.A., 192.
Hunyadi Jfinos and Uj Hunyadi Waters
(Saxlehner v. Apollinaris Co), 157, 195,
224a.
Huxley Memorial Fund, Remarks on the, 54.
Hyacinth Perfume, Formula for, 460.
Hydrargjri Nitratis, Ungueutum (Lucas),
121 ; (Squire), 172 ; (Maben), 223 ;
(Squire), 244.
July 3, 1897.)
Hydrocarbons from American Petroleum,
Some (Yeung and Thomas), 238.
Hydrogen, Peroxide of, in Oto-rhinology
(Gelle), 158.
— Union of Carbon and (Bone and Jerdan),
287.
Hydrokinone and Pyrogallcl Developer,
Formula for, 408.
Hydrolysis of Perthiocyanic Acid (Chatta-
way and Stephens), 320.
Hydroxylamine Sulphate (Divers and Haga),
367.
Hypophosphites, Formula for Extract of
Malt and Oil with, 484.
Hyposulphite, Sodium, for Parasites in
Cattle, 417.
Hyslop, J. C. — Lime Juice and Glycerin,
286.
— J. C. — Popular Pharmacy, 103, 117, 124.
— J. C. — Some Short Notes on Storage and
Pharmacy Arrangement, 481.
— J. C. — The Council Election, 483, 523.
I
Ice Cream, Formula for, 326,
Ichthyol as a Laxative (Gunsburg), 425.
— in Conjunctival Eczema, 363.
— in Erysipelas (Nabugnow), 425.
Idiosyncrasy Against Crabs (Kirschberg),
472.
Illustrated Journal, The Birth of an (Richard¬
son), 95.
Impersonation, A Case of (Rees), 199.
Incandescent Gas Mantles, Remarks on, 73.
Ince, Joseph — The Art of Literary Com¬
position, 292, 351.
— Joseph — The Latin of Pharmacy, 327.
— Joseph — The Prosody of Latin Phar¬
macy, 525.
Income Tax, Matrimony and the, 517.
— Tax, Overpaid (Income Tax Adjustment
Agency), 20.
— Tax Returns, Mr. Kearley on, 266a.
Indian Hemp, Remarks on the Active
Principle of, 93.
Individualism and Socialism in Pharmacy,
Editorial Remarks on, 181.
Ingham, John — The Case against the
P. A. T. A., 169.
— J. — The Regulation of Prices, 139.
Ink, Formula for Marking, to Use without
Heat, 524.
Ink for Rubber Stamps, Formula fur, 244.
— Powders, The Composition of, 568.
Inkstains from Paper, Removing, 200.
Inoculation of Nodule-Bacteria in Different
Host Species (Nobbe and Hiltner), 468.
Insect Powder, Poisoning with (Bosredon),
379.
— Powders of Commerce (Durrant), 505.
Insecticide for Plant Lice, Formula for, 314.
Insects, How Flowers attract (Plateau), 163.
Instruments, To Prevent Rusting of (Levai),
374.
Intensifier, Formula for Uranium, 408.
— One Solution Formula for an, 266.
International Exhibition and Market for
Paper-makers’ and Photographers’ Goods,
538.
— Pharmaceutical Congrers, Arrangements
for The Eighth (Brussels), 112, 147, 152.
Inverness Chemists’ A=soc’’ation, The, 408a.
Invisible Light, Remarks on, 52.
Iodide, Formula for Omtment of Starch
(Oefele). 513.
Iodides and Bromides, Alkaline (Knobloch),
460.
INDEX.
Iodine, Decoloration of Tincture of (Hager
and Remington), 266.
— in Cod- Liver Oil, Solubility of (Gibson),
199; (Guyer), (Groves), 223 ; (Gibson),
265.
— Value of Beeswax, The (Guyer), 308,
— Valsol, 484a.
— Vasol “ Hell,” 205.
Iodised Cotton, Manufacture and Examina¬
tion of (Soulard), 417.
Icdoform, Anczol or Deodorous (Diaz), 422.
— Substitute for, 274.
Iodogallate, Bismuth, Formula for the
Preparation of, 167.
Iodol, Pharmacy of, 167.
Iodothyroidin (Catillon), 287.
Ipecacuanha, The Anatomy of (Schneider),
112.
Ireland’s Advantages in Respect to Poison
Law, 558.
Irish Grievances, Som°, 342.
— Licence Examination, The (Vim et
Verve), 19.
Iron Carbide (Moissan), 367.
Irving, Sir Henry, Reading of Tennyson’s
“ Becket ” by (Farrar), 428.
Italy, Imports of Chemicals into, during
1896, 384.
Italy’s Chemical Trade and Productions,
406.
J
Jack, Mr. James, Presentation to, 40a.
Jackson, T. — Peach Kernel Oil and Oil of
Almonds, 285.
Japanese Opium Trade, 406.
Japan Wax, Adulterated (La Wall), 83.
Jenkins, H. C., and Smith, E. A. — On the
Reactions between Lead and the Oxides
of Sulphur, 423.
— T. — Difficulty in Dispensing Cocaine, 385.
Jesper, C. F. — A Royal College of Pharmacy,
427.
Johnson and Sons, Ltd. — A Correction re
Transfer of Business, 19.
— C. T. — The Approaching Council Elec¬
tion, 427.
Johnston, William — The Case for the
P.A.T.A., 168, 265, 344.
Jones, Dr. H. Macnaughton — The Therapeu¬
tics of Emergencies, 188.
— G. W.— “ Business Ways that are Dark,”
159.
— J. — The Students’ Page, 60.
Journal, The, and its Students’ Page (Kemp),
(J. P. K.), (Barrett), (H. D. K.), 79 ;
(Hickman), (Smith), 120; (Buckley),
(W. W.), 139; 182.
— The Society’s, Editorial Remarks on, 255.
J une, The Flowers of, 534.
Junior Pharmacy Ball, 140a, 160a.
Juroi’s Expenses, The Payment of, 541, 556.
K
Kathode and X-Rays (Swinton), 371.
Keen, B. — The Forthcoming Council Elec¬
tion, 325.
Kelly, P. — Chemistry, Ancient and Modern,
341.
Kemp, Harry — An appeal for the Benevo¬
lent Fund, 98, 198.
— II .rr/ — The Journal and the Students’
Page, 79.
Kew Gardens, John Burns on an Earlier
Opening Hour for, 342.
— The Botanic Gardens at, 270, 507, 526.
[Supplement to
Pharmaceutical Journal.
Kiliani, Dr., Appointment of, as Professor at
the Munich Polytechnic, 40a.
King, Typke and— The Keeping Qualities
of Essence of Lemon, 120.
Kinkelibah, 121.
Kinninmont Prize, The, 236.
Kino, Gelatinisation of Tincture of, 464.
Kites for Meteorology (Rotch), 379.
Kneipp, Father, Death of, 559.
Knott, Percy — Practical Photography,
266a.
Kobert, Dr. R„ Resignation of, 112.
Koch’s, Professor, New Compounds of
Tuberculin, 299.
Koh-i-Noor Soap, 484a.
Kritikstrahlen (Freidricb), 80a.
L
Label Paste for Gold Paper Labels, Formula
for, 266.
Labels, To Prevent Tins from Rusting
Through, 346.
Laboratory, The Chemical, in Pharmacy
(Mayer), 27.
Lactomaltine, 196.
Lady Dispensers as Candidates for Work¬
house Dispenserships, 538,
Lanolin Cold Cream, Formula for, 355.
Lantern Slides, Photo-Micro- (Phillips), 293.
Larkin, Charles — Digestion, 96.
Larvae, Arrow Poison from (Boehm), 468.
Latent Life of Seeds (Candolle), 468.
Lathrea Squamaria, To Prevent the Black¬
ing of, 335.
Lathyrus Sativus, Poisonous Properlies of
(McDougall), 290.
Latin of Pharmacy, The (Coull), 272 ; 291 ;
(Pollard), (Ashton), 305 ; (Ince), 327 ;
(Pollard), 364.
— Pharmacy, The Prosody of (Ince), 525.
Laudanum, Coroner Wightman on the Sale
of, in Sheffield, 338.
— for Black Draught, 60a, 73.
Lavender Industry, The, 52, 59, 92.
Law Society, The Incorporated, and its
Statutory Duties, 376, 413.
Lead and the Oxide3 of Sulphur, Oa the
Reactions between (Jenkins and Smith),
423.
Leather Polish, Composition of, 544.
Legal Hints for Pharmacists, 176, 268, 353,
458.
— Intelligence, 56, 77, 118, 136, 157, 194,
221, 224a, 241, 252, 273, 303, 363, 366a,
405, 414, 457, 500, 510.
Leicester Chemists and the P.A.T.A., 156.
— Chemists’ Association, 408a.
Lemon, Essence of, The Keeping Qualities
of (Typke and King), 120; (Robins),
159.
— Juice in Ophthalmia Neonatorum (Sza-
welski), 134.
— Oil, Haensel’sTerpeneless, and the French
Customs, 386a.
Lemonade Powder, Formula for, 306.
Lethal Chambers, Gas for, 386.
Lewes, Prof. Vivian — The Use of Gas fir
Domestic Lighting, 65.
Lewin, Prof. — Suppositories and their Manu¬
facture, 411.
Library, A Technical, 464.
— The Society’s, in 1896, 7.
L-'cence, Difficulties about a Chemist’s, 120a.
Licensing (Scotland), Acts Amendment Bill,
518, 556.
Liebig’s Extract of Meat Company, Financial
Condition of, 464 d, 504a.
Supplement to
Pharmaceutical Journal.
Liebig’s Extract of Meat Company, Ltd., v.
Bovril (British, Foreign and Colonial),
Limited, 399.
Liebreich, Dr. Oscar, Twenty-tifth Anniver¬
sary of, as Director of the Pharmaco¬
logical Institute, Berlin University, 33.
Light, Artificial (Hovenden), 155.
— Influence of, on the Growth of Plants
(Stameroff), 467.
— The Action of, on Diastase and Its Bio¬
logical Significance (Green), 528.
— The Nature and Polarisation of, 32 ;
(Thompson), 52.
Lilac Perfume, Formula for, 460.
Lime Cream and Glycerin, The Sale of,
253, 274, 278 ; (Hyslop), 286 ; 298, 303,
363,416, 421; (Beven), 463; (Webber),
483 ; (Strickland), 502.
— Juice and Glycerin, Formula for Real,
386.
Limes, Manufacture of, 40.
Ling, A. R., and Baker, J. L. — The Action of
Diastase on Starch, 94.
— A. R. and Baker, J. L. — The Solution,
Density, and Cupric Reducing Power of
Dextrose, Levulose, and Invert-Sugar,
94.
Linimentum Belladonna, Remarks on a Case
of Poisoning by, 450.
— Calaminre, Improved Formula for (Skin¬
ner), 513.
Lin. Potass. Iodidi c. Sapone, Reaction in
Making, 464.
— Terebinthinre B.P., The Proportions of,
346.
Linnean Society of London, 115, 216, 280,
300, 340, 400, 456, 544a, 567.
Lip Salve, Formula for, 9.
Liquefaction of Air (Hampson), 287.
Liquid Air as an Agent of Research (Dewar),
400, 423, 456.
— Oxygen, The Properties of (Dewar), 94.
Liquor Bismuthi (Brown), 39.
— Licensing Laws Commission, Remarks cn
the, 278.
Liquorice Root Trade of B itcum during
1896, 568a.
Liq. Strontii Bromid., Formula for, 140.
List of Honours, The Jubilee, 559.
Literary Composition, The Art of (Ince),
292, 351.
— Notes, 49, 114, 216, 359, 376, 396, 477.
Liverpool Chemists and the P.A.T.A., 54,
455.
— Chemists’ Association, 54, 116, 219, 284,
302, 38.3.
— Pharmaceutical Students’ Society, 55, 77,
96, 135, 191, 239, 300, 321, 363.
Liverseege, J. F. — Food Products, 55.
Living Tissues as Chemical Reagents (Wild),
125.
L'cal Associations, The Increase in (Editorial
Remarks on), 71, 237.
— Government Board, The, and Over¬
pressure of Work, 324.
— Pharmaceutical Associations and the
P. A.T.A., 182 ; (Glyn- Jones), 350.
Locke, W. Makepeace — The Profession of
Pharmacy from an Assistant’s Point of
View, 143.
London Institution, 115.
— Residential Club, A, 486.
— Teaching University, The Prospect tf a,
461.
— v. Country Members of Council (Norfoik-
ensis), 385.
— Water Supply, The Effects of Continued
Rain on the, 358.
INDEX.
Lo ogata ff, W. Luther — An Assistant’s Quali¬
fication Wanted, 365.
Loofahs and other Foreign Goods, 464&.
Lorantbacem, Fertiiisation and Germination
of (Keeble), 83.
Lowe’s, Dr., Pure Water Test, 60.
Lucas, E. W. — The Ointments of the B.P.,
121.
Lunan, George — The Specific Gravities of
the B.P. Preparations, 219.
Lure for Earwigs, 275, 335, 366.
Lycetol in Gout and Rheumatism ( De
Tollenaere), 521.
Ly sidine and Piperazine as Uric Acid Solvents
(Goodbody), 89.
M
Maben, Thomas — The Forthcoming Council
Election, 364.
— Thomas — Unguentu m Hydrargyri N i t ratis,
223, 265.
McConnell, A. H. and Hanes, E. S. — The
Oxides of Cobalt, etc., 238.
Mace, Histology of (Schneider), 288.
MacEwan, Peter — Science and the Imagina¬
tion, 258.
Mackay (John) and Co.’s Dinner and
“ Smoker,” 100a.
McMillan, John — An Assistants’ Qualifica¬
tion Wanted, 345.
MacNaught, A. — The Dose of Tincture of
Strophanthus, 325.
Macpherson, C. A. — A Scheme of Exchange,
135.
— C. A. — An Adulteration of Pimento, 75.
Maggots in Canary Seed, 100.
Magistrates and Doctors, and the Sale of
Food and Drugs Act at Nottingham,
536.
Mugnesite Quarries in Greece, 461.
Magnetic Rocks (Folgheraiter), 371.
Mahogany Varnish, Formula for, 20.
Mair, Sheriff, as a Pupil, 496.
Major Examination Results, Remarks on the,
33.
— Students’, Help for (Buckley), (W. W.),
139.
Malarine, Formula of, 405.
Malic Acid in Cider, 524.
Malt, Extract of, and Oil with Hypophos-
phites, Formula for, 484.
— Extract, An Active, 464a.
Manchester Chemical Club Library, Addi¬
tions to the, 20a.
— Pharmaceutical Association, 60a, 140a,
125, 244a, 266a.
— Pharmaceutical Association, The Forma¬
tion of the (Wilkinson), 19.
Manna of the Israelites, Remarks on the,
152.
Manure, New versus Old, 472.
Marburg, The Botanical Institute and Garden
at (Martindale), 174.
March, The Flowers of, 254, 276.
Marine Diatoms, Reproduction of (Murray),
163.
Marking Ink to Use without Heat, Formula
for, 524.
Martindale, W. — On the Desirability of Estab¬
lishing an Institute for the Teaching of
Botany in the Royal Botanic Gardens,
203.
— W. — On the Preservatives of Pharma-
copoeial Preparations, 227.
— W. — The Preparation of Boroglyceride,
80.
— W. Harrison — The Botanical Institute
and Garden at Marburg, 174.
[July 3, 1897.
Martin, N. H.— Pharmacy, Some of its
Dangers and Duties, 283.
Materia Mqdica in the University of Glas¬
gow, Editorial Remaiks on the Chair
of, 558.
Matrimony and the Income-Tax, 517.
Matter, Editorial Remarks on the Inner
Structure of, 151.
Matthews, F. E. — An Improved Apparatus
for Steam Distillation, 134.
May, The Flowers of, 418.
Maturin Copaiba Balsam (Dietze), 369.
Maybells Perfume, Formula for, 460.
Mayer, J. L. — The Chemical Laboratory in
Pharmacy, 27.
Measures used in Prescriptions, 70.
Meat, Examination of Potted (Remmlingei ),
472.
— Malt and Qainine Wine, Formula for, 524.
Mechanism of Sensitiveness (Borzi), 370.
Medical and Phaimacy Act Amendment
Bill for the Cape, 496.
— Boycott at Plymouth, The Proposed, 378,
399, 559.
— Council, The General, 476.
— Environment, Remarks on the, by Dr.
Campbell Black, 33.
— Quacks and the Credulity of the Public,
299.
Medicated Pencils, 153.
— Wines, Remarks on the Sale of, by
Chemists, 338.
Medicinal Herbs and Plants, Cultivation of,
in Russia, 58.
Medicine Cases, New, 464a.
— Editorial Remarks on Methylene Blue in,
420.
— Stamp Act, Proceedings under the, 132 ;
(Lambeth), 136.
— Stamp Acts, Legal Hints on the, 353, 458.
— Stamps, A Suggestion (Smith), 462.
Medico-Hygienic Inventions’ Company,
Limited, 160a, 197.
Memory in Fishes, Remarks on the Existence
of, 93.
Menthol in Peppermint Oil, Determination
of (Kebler), 367.
Mentholated Crayons, Formula for, 167.
Merchandise Marks Act, 1887, Select
Committee on the, 262, 295, 343, 494.
Merck Pharmacy, Editorial Remarks on the,
377.
Mercuric Chloride as a Remedy for Potato
Diseaae, 417.
Mercary Benzoate (Rebiere), 82.
— Determination of, in-Ammonio Mercuric
Chloride (Thompson), 117.
— in Hair Wash, 366.
— Pyroborate (Tokayer and Dupuoy), 82.
— The Behaviour of Chlorine, Bromine and
Iodine with (Shenstone), 94.
Metcethyl as a Local Anaesthetic, 368.
Metallic Solutions, 151; (Heycock and
Neville), 319.
Meteorology, Kites for (Rotch), 379.
Methyl Blue and Methylene Blue, The Differ¬
ence Between, 386.
— Violet for Boils, Carbuncles, and Anthrax
(Trenite), 126.
Methylated Spirit, Legal Hints for Pharma¬
cists Concerning, 176.
— Spirit, The Sale of, 306.
Methylene Blue in Medicine, Editorial
Remarks on, 420.
— Blue Internally in Gonorrhoea (Moore),
405.
— Blue in Rheumatoid Arthritis (Philpots),
426.
Metol, Formula for, 224.
July 3, 1897.]
Metric Measures and Our Old System (Toms),
68, 147.
• — Weights and Measures Bill, 109, 324, 473,
494, 556.
Mexican Imports and Exports, 58.
Microbes and the Australian Babbit Pest,
469.
— New Testament, 279.
Micro-Objects, Staining and Mounting of,
140.
— -Organisms in Milk (Hesse, Caro, and
Schotte), 162.
— -Photographs, 120.
Microscope, The, What it Do s, 30.
Microtome for Biological Work, A Simple
(Flatters-), 485.
Midland Chemists’ Assistants’ Association,
80 a, 303, 341, 380, 453.
— Pharmaceutical Association, 55, 97, 135,
266a, 519, 544 d.
— - Pharmaceutical Trade Committee, 219,
453.
Midwives Begistration Bill, The, 154, 413,
556.
Milk, Chemical and Bacteriological Examin¬
ation of (Davies), 302.
— Factory, A Sterilised and Humanised, 516.
— Preservative, 224.
— Variation in Richness of, 472.
Mineral Waters, Teneriffe, 38.
Minor, Books for the, 266, 504.
— Examira'ion Standard (Index), 463.
— Examination Syllabus, Bemarks on the,
72 ; (Audi Alteram Partem), 100.
— Man’s Grievance, A (An A. Ph. S.), 199.
Minute Organisms, as Causes of Disease
(Thompson), 85.
Mist. Arsenicalis, B.S H., 346.
— Ferri Perchloridi, B.S.H., 316.
Moissan, Henri — The Isolation of Fluorine,
499.
Molasses Mull, a New Cattle Food, 159.
Monol as a Synonym for Calcium Perman¬
ganate (Bordas), 196.
Monsonia Ovata (Maberly), 162; (Wood),
450.
Montreal College of Pharmacy Sessional and
Pharmaceutical Examinations, 368a.
Montserrat, The Flocds in, 20c.
Moon, The Influence of the, on Climatic Con¬
ditions (Whitmore), 469.
Morgan, H B. — Some Assistants I have Met
321.
— H. Marston — Crystallography, 146.
Morison, Dr. J. Louis D. — Histology of the
Vegetable Tissue Systems, 470.
Morphine, Alleged Purchase of Four Ounces,
in One Week, 422; (Goldby) 462.
— Hydrochloride as an Antidote to Potas¬
sium Cyanide (Heim), 158.
Morphological Botany, The Present Position
of (Scott), 34 ; 360, 478.
Mortar, The Antiquity and History of the
(Thompson), 267.
Moss, John — The Attfield Testimonial, 305.
Mosses and Ferns, Delation between
(Scott), 360.
Moths, Experiments cn '* Sugaring” for, 275.
Mould-Fangi, Mycele of (Marschall), 370.
Mountants for Diatoms, 80.
Moustache Fixing Fluid, Formula for, 390.
Mouth-wash Tablets, Formula for (Berne-
gan), 374.
Mumbray, B. G. — The Benevolent Fund, 78.
Mun’oy, A E. — A Bansen Burner for Acety¬
lene, 423.
Museum, The Society’s, in 1896, 7.
Museums Association Meeting at Oxford,
299, 518.
INDEX.
Mycele of Mould Fungi (Marschall), 370.
N
Names, The Lancet on Popular and Scientific,
379.
Nansen-Sverdrup Expedition, Bemarks on
the, 153.
Naphtha Wells of Baku, 568a.
/8-Naphthol and Bismuth Salicylate in
Infantile Diarrhoea (Solislchen), 405.
— in a Prescription (Morgan), 135.
Naphthosalicine as . an Antiseptic in Laun¬
dries, 314.
Naples Zoological Station, Twenty-Fifth
Anniversary of the, 358.
National Physical Laboratory, A, 133, 154,
183.
Natural History Notes, 177, 275, 335.
Naval Dispenserships, 215; (Videre est
Credere), 365.
— Storekeeper, The Position of, 517.
Nectaries, Septal (Schniewind-Thies), 467.
Nervosin for Neurasthenia and Hysteria
(Aufrecht), 553.
Nests of the Chimney Swallow, 300.
Neville, F. H., and Hey cock, C. T. — On the
Freezing-Point Curves of Alloys Contain¬
ing Zinc, 23 8.
Newball and Mason’s Annual Dinner, 40a.
Newcastle Chemists and the P.A.T.A., 75.
— on-Tyne Chemists’ Association, 118, 224a,
381, 386a.
— on-Tyne, The Proposed Association at
(Clague), 80.
New Ideas and Trade Notes, 8, 57, 74, 196,
263, 293, 326a, 346a, 366c, 336a, 464a,
484a, 504J, 524a, 544a.
— Mown Hay Perfume, Formula for, 355.
— Bemedies, 58, 158, 196, 221, 363, 405,
425.
— X Bays (Friedrich), S0a.
— Year Honours, The List of, 32.
Newspapers, Post Office Test Case on Be turn
Postage of, 257.
Nickel, Action of, upon Ethylene (Sabatier
and Senderens), 319.
— in Telephones (Garrett and Lucas), 371.
Night Lights, Fowler’s, 544a.
Nile, The Use of the, as a Source of Elec¬
tricity, 339.
Nitrate of Copper, The Separation of, from
Nitrate of Silver in the Manufacture of
Caustic (Warder), 61.
Nitrites in Water, Test for (Barbet and
Jandrier), 456.
— Method of Determining Minute Quanti¬
ties of (Zambelli), 169.
Nitrogen, Assimilation of (Laurent, Marchal,
and Carpiaux), 289.
— The Oxidavion of (Rayleigh), 134.
Nitrous Acid in Aqua Destillata (CouT),
199.
— Ether, The Sale of Spirit of, at North-
fleet, 540.
— Oxide and Destructiveness, 422.
Nodule-Bacteria in Different Host- Species,
Inoculation of (Nobbe and Hiltner), 468.
North of England School of Chemistry and
Pharmacy (Annual Dance), 140a.
— Staffordshire and District Chemists’ As¬
sociation, 258, 261, 404.
Notes and Formulae, 167, 355, 374, 3S6, 417,
460, 472, 493, 513, 530.
Nottingham and Notts Chemists’ Associa¬
tion, 100a, 193, 306a, 321 ; (Annual
Meeting), 482.
Nursery and Toilet Powder, Formula for, 9.
Nux Vomica, Assay of Extract of, 20. |
Supplement to
Pharmaceutical Journal.
Nymphseacere, Morphology and Anatomy of
Some of the (Vaughan), 216.
O
Oak Varnish, Formula for, 20.
Oaths, Sir Walter Foster and the Mode cf
Administering, 473.
Obituary : (Boberts), (Davies), (Eaker),
(Schacht), 20 ; (Bennett), (Roger), 40 ;
(Skirrow), (Howson), (Venman), (Blan-
shard), 78 ; (Williams) (Riley), (Mather),
(Crarer), (George), 100 ; (Nind), (Burn),
(Hunt), 120; (Dadley), (Miller), (Steven¬
son), (Lewis), 140 ; (Nurthen), (Brown),
(Huggins), (Kay), (Southwell), (Downie),
(Johnston), 160; (Bradley), (Howe),
(Taylor), 198 ; (Howard), (Sanson), 222;
(Laws), (Cupit), 244 ; (Stocker), (Pratt),
(Taylor), (Payne), (Byder), 266; (Coleby),
(Hall), (Alford), (Dyer), (Bae), 286 ;
(Herbert), (Boper), (Marshall), 303;
(Thomas), (Bagley), (Chessall), (Allis),
(Blatchley), 326; (Staffing), (Bulcock),
(Jeffery), (Watts), (Backhouse), 343 ;
(Earee), (Sarsfield), (Cawdell), (Armi-
tage), 366 ; (Solomon), (Barber), (Press-
lie), (Thornton), 386 ; (Nants), (Smith),
(Trollope), 408 ; (Lumley), (Hopkinson),
(Moore), (Merson), 428 ; (Hemingway),
(Barber), (Sturges), (Ford), (Walters),
(Willson), (Hodder), (Stearn), 459 ; (Hol¬
land), (Blackshaw), (Morris), (Byder),
(Raynor),(Savage), (Cardwell), (Nicholls),
(Maitland), 484; (Keyworth), (Starie),
(Lambert), 504 ; (C ater), (Sutherland),
(Wood ), (Griffith ) (Kdsington), (Farrage),
524 ; (Harrison), (Parker), (Bowe) (Burn¬
ham), 544; (Westrup), (B'mmingtor),
(Squire), (Scanlan), 568.
Odd-, A Knowledge of the, 279.
CEnothera, Opening of the Flowers of (Plan-
chon), 468.
Oil of Spike, 200.
Ointment for Pustular Acne, 425.
— for Ulcerated Leg, Composition of, 386.
— of Starch Iodide, Formula for (Oefele),
513.
— To Colour and Perfume, 366.
Ointments of the B.P., The (Lucas), 121.
Old Price List, An, 556.
Olive Oil, Extraction of, in Persia, 38.
— Oil, The Italian Government and the
Adulteration of, 461.
Oliver, Prof. F. W— Botanical Lectures
before the Apothecaries’ Society, 453,
522.
Olives, Cultivation cf, in Cadiz, 58.
Onion, John — A Personal Complaint, 139.
Opium, East Indian, Beport on, 237.
— The Ceylon Government and, 137.
— The Beturns of Duty and Likin on Chi¬
nese, 384.
— Trade, Japanese, 406.
Optical Classes, The Importance of Attend¬
ing, 379.
Orange Bitters, Formula for, 9.
Organic Liquids and Oxidation (Bourquelot),
466.
— Nourishment of Green Plants (Bokcrny),
370.
— Substances, Drying Sensitive (Parsons),
465.
Otto of Boses, Eastern Roumelia, 58.
Ovaline Preparations, 464 a.
Ovules without a Nucellus (Tieghem), 370.
Oxalic Acid, To Obtain Pure (Riechelmann),
460.
INDEX.
[July 3, 1897.
Supplement to
Pharmaceutical Journal.
Oxford and District Chemists’ Association,
286a, 401.
Oxidation of Ferrous Carbonate, 464.
— of Nitrogen, The (Rayleigh), 134.
— of Silver (Wait), 81.
Oxide, New Phosphorus (Besson), 368.
Oxides of Cobalt, The, Cobaltites, etc.
(McConnell and Hanes), 238.
Oxygen Gas, The Treatment of Wounds by,
477.
— in Ascites (Teissier), 425,
Oyster Beds, The Local Government Board
and, 343.
Oysters, Copper in (Lowe and Herdman),
162 ; (Lowe), 493.
Ozone, The Inflaence of Moisture on the
Production of, from Oxygen (Shenstone),
94.
— The Stability of (Shenstone), 94.
P
Panegyric, A (Hick), 100; (Coull),
(Borax), (Freethinker), 119.
Paraffin -Naphthalin Emulsion as a Plant
Insecticide, 460.
— Oil, Purification of, 346.
Paraf. Javal Solution (Pharmacist), 20 ;
(Robertson), 39.
Paraffinum Molle, Preparation of, 544.
Parasymbiosis of Fungi (Zopf), 468.
Parish Dispensary, Visit to a, 175.
Park, C. J. — Chemists’ Federation, 99.
— C. J. — The Proprietary Articles Trade
Association, 285.
Parker, R. H. — The Benevolent Fund, 20.
— R. H. — Will Legislation help Pharmacy ?
156.
Parliamentary Bills, First Readings of
Private Members’, 97.
— and Legal Business in 1896, 3.
— Notes and News, 8, 69. 97, 109, 137, 154,
186, 212, 242, 262, 275, 295, 324, 342,
376, 407, 413, 461, 473, 494, 518, 541,
556.
Parthenium Hysterophorus, Examination of
(Arny), 370.
Partnerships Dissolved, 428*, 484a, 504a,
524a.
Paste for Gold Paper Labels, Foimulafor,
266.
— for Labels on Tins, Formula for, 200.
Past=ur Institute, Paris (Donation to the),
32; (Patients Treated), 73.
Pastilles, Formula for Carbolic Acid (Salz-
mann), 314.
Pa'ent Act;on (Wood v. Raphael) ; Appeal
Case, 464 d.
— Laws, Remarks on the Amendment of
the, 338.
— Office and the Trade in Aniline Dyes, 186.
— Office Protection, 494,
Patents, The Number of Applications for,
during 1896, 358.
Paul, D.\ B. H., and Cownley, A. J. — The
Alleged Conversion of Cinchonine into
Circhonidine, 141.
Peach Kernel Oil and Oil of Almonds (Jack-
son), 285; (Cowley). 305.
Pearson, John Henry — Note on Glycerinum
Amyli, 201.
Pellets, Soluble Antiseptic, 8.
Pencils, Medicated, 153.
Pender Memorial, The, 120a.
Penny-in-the Slot Electricity, Remarks on,
152.
Peppermint Oil, Determination of Menthol
in (Kebler), 367.
Perfume, “ 1897,” Formula for, 460.
— of Flowers, Extracting the (Pass}), 369.
Perfumes and Toilet Articles, 196, 524a.
— Some Formulae for Synthetic, 460.
Perfuming Programmes, Formulae for, 306.
Perkin, Dr. W. H. — The Synthesis of Cam-
phoronic Acid, 280.
Peronine, A New Morphine Derivative
(Merck), 217.
Peroxide of Hydrogen in Oto Rhinology
(Gelffi), 158.
Perthiocyanic Acid, The Hydrolysis of
(Chattaway and Stephens), 320.
Petroleum and its Products ; Their Pharma¬
ceutical Uses, 410.
— Benzene for Removing Grease Spots,
408.
— Emulsion, Formulae for, 200, 484.
— Licence Prosecution, 428a.
— Some Hydrocarbons from American
(Young and Thomas), 238.
— The Committee of Inquirv on, 97, 186,
242, 262, 324.
Pharaoh’s Serpents, The “Eggs” Pro¬
ducing, 298.
Pharmaceutical and Medical Assistance for
the War in Greece, 398.
— Appliances, Novel, 406.
— Chemist, The True, 450.
— Chemists’ and Apothecaries’ Assistants’
Association of Ireland, 54, 96, 140a, 258,
284, 341, 454.
— Congress, The Eighth International
(Brussels), 112, 147, 152, 191.
— Development During Sixty Years, 1837 to
1897, 545.
— Football Club, 60a, 80a, 140a, 160a, 244a,
266d ; (Past v. Present), 286a.
— Journal, The, and Changed Ideals (Edi¬
torial Remarks on), 12.
— Life, The Part of Combination in Modern
(Clague), 381.
— Progress in 1896, 1.
— Scholarships, Three, 476.
— Secrets, A Physician on, 450.
— Society and the Daily Press, Remarks on
the, 214.
— Society as Representative of the Whole
“Trade,” Remarks on the, 318.
— Society, Editorial Remarks on the Dual
Function of the, 419.
— Society of Ireland(CouncilMeetiDgs), 40a,
136, 341.
— Society of Ireland (Preliminary Exam¬
inations Results), 55 ; 73, 258; (April Ex¬
aminations), 266a ; 341; (Licence Exam¬
inations), 366a ; 425, 520 ; (July Exam¬
inations), 539.
Pharmaceutical Society, Transactions
OF THE I —
Address to the Queen’s Most Excellent
Majesty, 489, 531.
Adjourned General Meeting, 445.
Annual General Meeting, Amendments
to be Moved to the Proposed New
Bye-Laws, 398.
— Meeting, Date of Fifty-Sixth, 206, 214,
(Meeting), 432.
— Report of the Council, 387.
Associates, Election of, 45, 105, 205, 309,
391, 489.
Auditors, Nomination and Appointment
of, 310, 437.
— Report, 389.
Benevolent Fund Committee, Reports of
' the, 46, 105, 206, 312, 393, 490.
— Fund Festival Dinner, 108, 398, 429.
— Fund, List of Donations and Subscrip¬
tions in Aid of the, 451, 491.
Pharmaceutical Society— continued.
Brussels, The International Congress at,
207, 309, 391.
Bye-Laws, Proposed New, 207, 210, 236,
310, 315, 393.
Calcium Carbide, The Sale of, 206, 212,
234, 309, 318.
Committees, Appointment of, 489.
Correspondence, 310, 313, 394, 491.
Council Election, Result of the, 445.
— Meetings, 44, 105, 205, 309, 372, 391,
432, 488.
— Nominations for the, 309.
Diplomas, Granting of, 45, 391.
Diplomas of Deceased Members, 46.
Donations to the Library and Museum,
74, 127, 238, 252, 372, 413, 531
Earee, Mr. Thomas, Death of, 391.
Evening Meeting in Edinburgh, 251.
— Meetings in London, 127, 232.
Examination First, Certificates Accepted
and Results, 47, 108, 334, 394, 412.
— Papers, Major, 9, 324.
— Questions, First, 48, 334.
Examinations, Analysis of, for the Year
1896, 107.
— in Edinburgh, Major Results, 48, 355.
— in Edinburgh, Minor Results, 48, 355.
— in London, Major Results, 34, 334.
— in London, Minor Results, 47, 334.
— in London, Report of the Government
Visitor on the, 310.
— Reports of the, 47, 105, 394.
Examiners for the Council Prizes and
Scholarships, Appointment of, 489.
Finance Committee, Reports of the, 46,
105, 206, 312, 393, 489.
Financial Statement for 1896, 388.
General Purposes Committee, Reports of
the, 47, 108, 207, 313, 394, 491.
Glasgow Conference, Arrangements for
the, 37 4
Government Visitor, Report of the, on the
Examinations in London, 310.
International Congress at Brussels, The,
207, 309, 391.
Letter and Resolutions re The Proposed
New Bye Laws, 310.
Library and Museum, Donations to tie,
74, 127, 238, 252, 372, 413, 531.
Library, Museum, School and House
Committee, Reports of the, 47, 108,
206, 312, 393, 490.
Members, Election of, 45, 105, 205, 309,
391, 489.
Nind, Mr. Geo., The Late, 105.
North British Branch, 372; (Annual
Report), 392; (Annual Meeting), 565.
Officers, Re-appointment of, 489.
President, Election of, 488.
Piize Examination Papers, School of Phar-
macy Sessional, 295.
Quebec, Pharmacy in, 47.
Registrar’s Report, The, 106.
Restorations to the Register, 45, 105, 206,
309, 392, 489.
Royal Botanic Society, Appointment of
the President as an Hon. Member of
the, 313.
Russow, Prof. Edmund, Death of, 391.
Sachs, Dr. Julius von, Death of, 489, 496.
Schacht, G. F., The Late, 44, 205.
School of Pharmacy Sessional Prize
Examination Papers, 295.
Scrutineers’ Report on the Election of
Council, 445.
Secretaries, Local and Divisional, Appoint¬
ment of, 47, 313.
July 3, 1897,1
r
Pharmac utical Society— continued.
Special General Meeting, 437 ; (Taplin),
464d.
Students, Election of, 45, 105, 206, 309,
391, 489.
Treasurer, Election of, 489.
Vice-President, Election of, 488.
Vote of Thanks to Mr. Gostling on his
Retirement, 490.
Vote of Thanks to the Retiring Vice-
President, 490.
Pharmaceutical Uses of Petroleum Products,
410.
Pharmacist, The, as a Photographic Dealer,
458.
— The Social Status of the (Glass), 543.
Pharmacists, The Position of, in the Social
Scale, Editorial Remarks on, 515.
Pharmacograpby in 1896, 18.
— The Study of Practical, 30, 170 ; (Editorial
Remarks), 215 ; 230, 269.
Pharmacopoeia, British, Explanatory Notes
on the, 10, 50, 70, 90, 110, 130, 150,
179, 254, 276, 296, 336, 356, 418, 474,
514, 534.
— Committee, The Report of the, 496.
Pharmacopoeial Preparations, On the Pre¬
servatives of (Martindale), 227, 234.
Pharmacy Act, The Difficulty of Administer¬
ing the, 398.
— Act, Cases under the, in 1896, 4.
— Act, Police Prosecution under Section 17
of the, 222.
— Act, Proceedings under the (Airdrie),
194, 221 ; (London), 222 ; (Glasgow),
241; (Hamilton), 242; (Airdrie), 252;
(Bow), 273 ; (Hamilton), (Edinburgh),
(Glasgow), 294 ; (Glasgow), 313 ; (Hey-
wood),326a; (Nottingham), 342; (Hamil¬
ton), 394; (Glasgow), 395; (Airdrie),
414 ; (Glasgow), 457 ; (Airdrie), 500 ;
(Preston), 540.
— Act (Ireland), Proceedings under the : —
(Moneymore), 80a.
— Act, Remarks on the Administration of
the (Scotland), 256 ; (London), 278 ;
(Scotland), 298,318; (Nottingham), 338.
— Arrangement, Some Short Notes on
Storage and, 476 ; (Hyslop), 481.
— Board of Victoria, The, 449.
— Individualism and Socialism in, Editorial
Remarks on, 181.
— in the East of Scotland, The Progress of
(Scottish Chemist and Druggist), 555.
— Old (Casson), 87 ; (Ashton), 138.
— Popular (Hyslop), 103, 117, 124.
— Practical, in 1896, 6.
— Progress in (Sinclair), 331.
— Some of its Dangers and Duties (Martin),
283.
— The Chemical Laboratory in (Mayer), 27.
— The Latin of (Ooull), 272, 291 ; (Pollard),
(Ashton), 305.
— Tne Profession of, from an Assistant’s
Point of View (Locke), 143.
— The Plough Court, 164.
— The Prosody of Latin (Ince) 525.
— The World of, 54, 75, 116, 135, 155, 188,
218, 239, 258, 281, 301, 320, 340, 362,
380, 401, 423, 453. 481, 519, 539.
Ph rmacy ? Will Legislation H dp (Parker),
156.
Phenacetin Tabloids, Compound, 8.
— in Typhoid (Bigaami), 29.
Phenamine and Triohenamine (Limlhorst
and Langkopf), 530,
Phenetidine, Citrates of (Heyden), 24.
Phonograph Wax, Composition of, 408.
INDEX.
Phosphate, Ferrous (Evans), 141.
— Quarries of Orville, 568a.
Phosphides of Platinum (Clarke and Joslin),
82. '
Phosphorus Oxide, New (Besson), 368.
Photographic Convention, The, 473.
— Dealer, The Pharmacist as a, 458.
— Methods, The Production of Colour by
(Wood), 187.
— Notes, 473.
— Record, Proposal for a National, 358.
Photography and Physics in 1896, 14.
— in Natural Colours, 111, 132, 172, 187,
473.
— Practical (Knott), 266a.
— Some Applications of (Wall), 516.
Photo-Micro. Lantern Slides (Phillips), 293.
Physical Laboratory, A National, 133, 154,
183.
— Laboratory for India, A, 339.
Physics and Photography in 1896, 14.
Physiological Experiments, The House of
Commons and, 407.
Pig Bile Tabloids, 524a.
Pigments of Plants (Newbigin), 289.
Pil. Rhei Co., Pulv. pro., 464.
Pilocarpic and Pilocarpidic Acids (Petit and
Polonovski), 466.
Pilocarpidine in Pilocarpine Salts (Petit and
Polonovski), 466,
— Origin of (Petit and Polonovski), 466.
Pilocarpine and Pilocarpidine (Petit and
Polonovski), 466.
— The Constitutioa of (Knudsen), 161.
Pill, Excipient for, 464.
Pimento, An Adulteration of (Macpherson),
75.
Piperazine and Lysidine as Uric Acid
Solvents (Goodbody), 89.
Piperidine Guaiacolate (Schidrowitz), 81.
Plant Insecticide, Paraffin-Naphthalin Emul¬
sion as a, 460.
— Lice, Formula for Insecticide for, 314,
Plants, Absent, 275.
— Bacterial Diseases of (Peglion), 162.
— Formation of Secretions in (Tschirch),
289
— Fossil (Seward), 127.
— Influence of Light on the Growth of
(Stameroff), 467.
— Organic Nourishment of Green (Bokorny ),
370.
— Pigments of (Newbigin), 289.
— Protecting Rare Species of, 275.
— Registration of, 339.
— Spread of Immigrant, 275.
— Winter green (Lidforss), 83.
Plaster Press, A New, 406.
Plasters, Manufacture of Rubber, 396.
Plate Powder, Formula for, 326.
Platinum Chloride, Recovery of Waste
(McElroy), 287.
— Pnosphides of (Clarke and Joslin), 82.
Playfair, Lord, on Sanitary Law, 559.
Plough Court Pharmacy, The, 164, 247.
Plymouth, Devonport, Stonehouse and Dis¬
trict Chemists’ Association, 56, 116, 136,
191, 218, 284, 303, 362, 425, 454, 484a,
504a, 521.
— Medical Men and Friendly Societies, 378,
399, 559.
Poet of the North, The Pharmaceutical, 279.
Poetry and Business, 464A
Poison Book, The Police and the, 504.
— Law, Ireland’s Advantages ia Respect
t", 558.
Poisoned Grain, Sale of, 461c7.
Poisoning by Ammonia (Oldbury), 286a.
— by Buttercups (Lancaster), 517.
Supplement to
Pharmaceutical Journal.
Poisoning by Carbolic Acid (Torpoint), lOOrf ;
(Leytonstone), (Burton-on- Trent), 386a,
(Bulwell), 537.
— by Chloral (Handsworth), 386a.
— by Chlorodyne (Folkestone), (Newport),
57 ; (Southport), 100<7.
— by Chloronette (Dunmow), 298.
— by Copaiba (Thompson), 369.
— by Hydrocyanic Acid (Lyndhurst), 524a.
— by Insect Powder (Bosredon), 379.
— by Laudanum (Newport), 20 cL ; (Liver¬
pool), 60a, 73; (Llandysilis), 100 cl\
(Carrington), (Clifton), 160a ; (Cother-
stone), (Dublin), 504a.
— by Liniment (New Wortley), (High
Buckholmside), 20 d ; (Norwich) (Brad¬
ford), 57.
— by Linimentum Belladonnas, Remarks on
a Case of, 450.
— by Prussic Acid (Dublin), 20d.
— by Sulphate of Ammonia (Warwick),
20 d.
— by Sulphuric Acid (Sparkhill), 57,
— of Elephants, The, 421.
Poisonous Honey (Gerpen), 289.
— Properties of Lathyrus Sativus (Mc-
Dougall), 290.
Poisons and Poisonous Vapours, Deaths
Caused by, 477.
Polarisation of the Electric Ray, The (Bose),
116.
Pollard, H. H. — The Flowers of January, 39.
— H. H. — The Latin of Pharmacy, 305,
364.
Pollen and Ovule, Homology of the (Mol-
liard), 83.
— Protection of, from Rain (Hansgirg), 163.
— Grain, Spermatozoids from the, 92.
Pollens, Study of (Pfister), 467.
Pomade, Formula for Floral, 306.
Position of Pharmacists in the Social Scale,
Editorial Remarks on the, 515.
Postage Rates on Foreign Letters, 556.
Postal and Telegraph Reforms, 407, 408a,
450, 556.
— and Telegraphic Service, Cycles and the,
262.
Post-Office Anomalies, English, 319.
Potassium Bichromate as an Expectorant
(Weaver), 323.
— Compounds, The Detection of, 339.
— Permanganate in Lupus (Butte), 426.
Potato Disease, Mercuric Chloride as a
Remedy for, 417.
“Potato Drops and Green Mallet” (Evans),
385.
Potted Meat Examination of (Remmlicg-r),
472.
Potter, Mr. A. H., Presentation to, 326a.
Poultry Powder, Ingredients of a, 140.
— Spice to Make Fowls Lay, Forum’ a for,
60.
Preece, W. H. — Signalling Through Space
Without Wires, 521,
Preferential Payments in Bankruptcy Act
(1889) Amendment Bill, The, 324.
Prehistoric Human Relics (Piette), 84.
Preliminary, Books for the, 504.
— Examination, The (Cardell), 140.
— Examination uf the Pharmaceutical So¬
ciety (Ireland), Is the, a Sufficient Test
of Preliminary Education ? (Harris), 54.
Prescribing, On Counter (Barrass), 244.
Preservatives of Pharmacopoeial Prepara¬
tions, On the (Martindale), 227, 234.
Preserving Tomatoes, Method of, 513.
Price List. An Old, 556.
Proctor, B. S. — Notes on Dispensing Sixty
Years Ago, 553.
• Supplement to
XVI Pharmaceutical Journal.
Professional and Commercial Interests,
Editorial Remarks on, 495, (Glyn-Jones),
503.
Programmes, Formulae for Perfaming, 306.
Progress, Editorial Remarks on Some Fea¬
tures of, 557.
_ of Pharmacy in the East of Scotland, The
(Scottish Chemist and Druggist), 555.
Proprietary Articles, The Trade in, Editorial
Remarks on, 71.
— - Articles Trade Association (Glyn-Jones),
23.
— Articles Trade Association and Dealers in
Photographic Materials, 215.
_ Articles Trade Association and Local
Pharmaceutical Associations, 182 ; (Glyn-
Jones), 350.
_ Articles Trade Association and Pharma¬
cists, 13, 54, 60a, 75, 77, 93, 156, 192;
(Election of Council), 192 ; 218, 224a;
(Election of Representatives), 259;
285, 298, 320 ; (First Annual Meeting),
321 ; 454, 455.
— Articles Trade Association, Grocers and
the, 516, 558.
_ Articles Trade Association, Remarks
on the Rapid Progress of the, 318.
P.A.T.A. Methods, The Legality of the, 378.
P.A.T.A., The Case For and Against the
(Johnston), (Ingham), 168; (Midlothian),
223 ; (Johnston) (Catalysis), 265 ;
(Park), 285; (Midlothian), 304 ; (Clower),
(Johnston), (A.J.R.), 344.
P.A.T.A., The Society and the (Atkinson),
( Hy slop), 483 ; (Sharman), 502; (Glyn-
Jones), (Hinde), 503; (Hyslop), (At¬
kinson), 523; (Glyn-Jones), (An Old
Pharmacist), (Young), 542 ; (Atkinson),
568.
Prosody of Latin Pharmacy, The (Ince),
525.
Protection of Prices, The (Barrett), 38 ;
(Junior Senex), (Thompson), 59; (Snook),
(A Pharmaceutical Chemist), 78, 79 ;
(Honest Trader), (Scupham), 99 ; (Ray),
(Ingham), 138, 139; (Johnston), (Ing¬
ham), 168; (Midlothian), 223; (John¬
ston), (Catalysis), 265; (Park), 285;
(Midlothian), 304; (Clower), (Johnston),
(A.J.R.), 344.
— of Trade Interests, Editorial Remarks
on the, 31.
Proteids, Formation of (Kosutany), 370.
Psychological Laboratory at University
College, London, The Proposed, 477.
Pablie Analysts and Somerset House
Disagree, 298, 378, 421.
— Analysts, Editorial Remarks on the
Danger cf, 535.
— Analyst’s Omission, A, 496.
— Health Act Amendment Bill, The, 413.
— Health Congress, A, 559.
— Health, Ministry of, 98.
Pnlv. Pro Pil. Rhei Co., 464.
Purified Substances, The Properties of
(Shenstone), 465.
Purple of Cassius (Antony and Lucchesi),
368.
Pustular Acne, Ointment for, 425.
Pyrene Oil, The Manufacture of, 568a.
Pyridine Derivatives from Ethylic-/3Amido
Crotonate, The Production of (Collie),
187.
Pyro. Developer, A Novel, 464&.
Q
Quacks, Medical, and the Credulity of the
Public. 299.
INDEX.
Qualifying Examination, Remarks on the
Results of the, 53.
Quassia, Characteristics of (Hills), 467.
Qaebec Pharmaceutical Association, 568c.
Question, A (Enquirer), 428 ; (Ashton), 462.
Quicksilver Mines at Almuden, The, 384.
Quininse Citras, Ferri et, and Potass* Citrus,
Dispensing Experience with (Wokes),
321 ; (Stratton), 344.
Quinine, A Record in, 113.
— Enema of, in Whooping Cough (Schulze),
58.
— Powders, The Sale of, in Madras, 80a.
R
Rabbits and Microbes, 469.
Rabies, Dr. Farquharson and Reported
C&S6S of 27 5
Radiography, Practical 22, 63, 122, 246.
Rae, Mr. Alexander, Death of, 286a.
— VV. J. — The Benevolent Fund, 159.
Railway Return Tickets, The Question of,
154.
Rawling, W. J.— The Proposed New Bye-
Laws, 384.
Ray, G. W. — The Regulation of Prices, 138.
Rayleigh, Lord— The Oxidation of Nitrogen,
134.
Reaction in Making Lin. Potass. Iodidi c.
Sapone, 464.
Reactions Between Lead and the Oxides of
Sulphur, On the (Jenkins and Smith),
423.
Reagents, Reactions, Methods and Formulae
Known by the Names of Their Authors,
491, 509, 531.
Red Furniture Cream, Formula for, 20.
Reduction by Calcium Carbide (Warren), 81.
Rees, Chas. J.— A Case of Impe’sonation,
199.
Registration as a Panacea for All Wees,
343.
— of Firms, The Qaestion of, 154.
Reminiscences of the School of Pharmacy
(Giles), 560 ; (Reynold-), 562 ; (Groves),
(A Student), 563.
Remuneration, Editorial Remarks on Che¬
mists’, 297.
Rennet, Essence of, To Prepare, 504.
Research, Higher, in Chemistry, 113.
Residential Club, a London, 486.
Resin, Guaiacum (Doebner and Lticker), 369.
Resinous Tinctures, Dispensing, 346.
Resins, Acaroid (Tschirch and Hildebrand),
370.
Resorcin in Seborrhma Capitis, 363.
Reviews and Notices of Books: —
American Pharmaceutical Association,
Proceedings cf the, 186.
“ Analyst,” A General Index to the, 493. .
Anatomischer Atlas der Pharmacognosie
und Nahrungsmittelkunde (Tschirch
and Oesterle), 375.
Australasian Medical Directory and Hand¬
book (Bruck), 49.
Bacteriological Diagnosis (Reid), 29.
Bacteriology, Aids to (Pearmain and
Moor), 186.
Bandaging and Surgical Dressing, Ele¬
mentary (Pye and Smith), 186.
Bazaar Medicines of India (Waring), 498.
Botanists’ Pocket Book, The (Hayward),
114.
Botany, Manual of (Green), 498.
Bournemouth, The Climate of (IOnsey-
Morgan), 49.
British Mosses, A Catalogue of (Dixon),
378.
[July 3, 1897.
Reviews and Notices of Books— contd.
Calenlar of the Pharmaceutical Society,
The, 49.
Chemical Dynamics, Studies in (van ’t
Hoff), 33.
Chemistry, First Stage Inorganic (Bailey),
359.
— Theore' ical and Practical, A Manual
of (Tilden), 333.
— Tutorial (Bailey), 185.
Chemists’ Assistants’ Association, Pro¬
ceedings of the, 216.
Chronicles of Christopher Bates, The
(Rees), 376, 396.
Dental Surgery for Medical Practitioners
and Students of Medicine (Barrett),
396.
Dentists’ Register for 1897, The, 257.
“ Die Umschau,” A New ScientificJ ournal,
49.
Economic Plants (Greshoff), 186.
Feeding of Infants, The (Cantley), 114.
Formulaire des Medicaments Nouveaux
for 1897, 359.
Gout and Goutiness and their Treatment
(Ewart), 28.
Guy’s Hospital Reports for 1896, 359.
Ham’s Inland Revenue Year - Book
(Hooper), 29.
Heavy Trial Balances Made Easy (Ciagg--),
49.
Herbal Simples Approved for Modern Uses
of Cure (Fernie), 185.
Kelly’s London Medical Directory for 1897,
114.
Knowledge, 216, 359.
Kodak News, 376.
Lean’s Royal Navy List, 114, 376.
Manuale der Neuen Arzneimittel (Mindes),
477.
Medical Annual and Practitioner’s Index,
The, 185.
— Chemistry, The Progress of (Thudi-
chum), 185.
— Register for 1897, The, 257.
Memoranda (Hearon, Squire and Francis),
185.
Merck’s Annual Report for 1896, 359.
Microscope, The Wonders of the (Poulson),
186.
Microscopy and Natural Science, The In¬
ternational Journal cf, 359.
Moring’s Quarterly, 376.
Natural Science. 216.
Photography, Imperial Text-Bock cf,
(Wall), 477.
— The Year-Book of, 396.
Physical Science, Chapters in (Cornish),
143.
Plant Description Schedules for (With-
art), 498.
Quackery, Exposures of, 114.
Quarantine in England (Collingridge),
477.
Reagents and Reactions known by the
Names of their Authors, 498.
Respiration of Man, A Contribution to the
History of the (Marcet), 375.
St. Thomas’s Hospital Reports, 1897,
333.
Schimmel’s Semi-Annual Reports, 376.
Science Goss;p, 216.
Science Progress, 49, 359.
Skin Pharmacopoeia (Startin), 359.
Squibb’s Ephemeris, 216.
Successful Advertising (Smith and Os¬
borne), 49.
Sudthausen’s, von, Guide for the Use of
Doctors and Apothecaries, 216.
July 3, 1897.]
Reviews and Notices of Books— contd.
Summer Tours in Scotland, 498.
Technical Education at the City and
Guilds of London Institute, Report on,
477.
Teeth, Extraction of the (Colyer), 396.
Therapeutic Value of the Hydrocarbons,
On the (Bayer), 477.
Useful Notes for Everyday Practice (Allen
and Hanbury), 185.
Water Analysis, A Simple Method of
(Thresh), 142.
Weights and Measures, Our (Chaney), 49.
Reversion, Editorial Remarks on a Case of,
377.
Reymond, Prof. Emil Du Bois, Death of 13.
Reynolds, Richard — A Case of Synanthy in
Dendrobium Brymerianum, 319.
— Richard — Reminiscences of the School
of Pharmacy (The Session of 1850-1),
562.
Rhamnus Barks, Comparison of (Sayre) 288.
Rhea Fibre, The Cultivation of (Playfair),
376.
Rhei Co., Pulv. Pro Pil., 464.
Richardson, E. W. — The Birth of an Illus¬
trated Journal, 95.
— F. W. — Bacteriology, 96.
— Sir Benjamin, The Late, 237.
Riding, J. — The Benevolent Fund Special
Appeal, 263.
Eimmington, Felix Marsh, Death of, 558,
568.
Ringworm Fungus, Formula for Staining,
167.
Roberts, L. A. — Botanical Specimens for
Students, 59.
Robertson, Alex. — Sol. Strontii Iodid. Paraf.
Javal, 39.
Robins, H. H. — The Keeping Qualities of
Essence of Lemon, 159.
Rogerson, M. and Son — A Royal College of
Pharmacy, 427.
Rontgen Light, Remarks on, 52.
— Rays, Chemical Inactivity of the, 133.
— Rays (Wilson), 218.
— X Rays, Power of Penetration of, Remarks
on the, 184.
Roper, R. F. — The Benevolent Fund, 137.
Rotting of Fruits (Wehmer), 163.
Royal Botanic Society, 217, 339.
— Commission on the Water Supply of
London, 407.
— College of Pharmacy, A (Greeoish),
408 ; (Forshaw), (Jesper), (Rogerson and
Son), 427; (Fyton), 462; (A Young
Chemist), 483 ; (Fyton), 542.
— Commissions and their Cost, 69.
— Institution, 94, 102, 116, 217, 400, 423,
428a, 456, 499, 521, 538.
— Photograph-' c Society, 266a.
— Photographic Society and the Photo¬
graphic Trade Exhibition, 379.
— Society Conversazione, 456, 499, 566.
— Society Fellows, The New, 559.
— Society of Edinburgh, 404.
Rubber Piasters, Manufacture of, 396.
Rubidamide, The Behaviour of, Towards
Ammonia (Titherley), 465.
Russell, J. Anderson- The Proposed New
Bye-Laws, 343.
Russow, Dr. Edmund, Death of, 399.
Rusting of Instruments, To Prevent the
(Levai), 374.
— through Labels, To Prevent Tins from,
346.
INDEX.
S
Saccharin, Discomfort from the Continual
Use of (Hogarth), 426.
Sachs, Dr. Julius von, Death of, 489, 496.
Saffron, Adulterated (Verb Sap), 223, 257,
— from Eastern Countries, 112.
Sale of Food and Drugs Act. (See under
Food and Drugs Act.)
Sale of Goods Act. (See under Goods Act.)
Saline, Formula for a Cheap, 266.
Salipyrine in Peliosis Rheumatica (Muhl-
bauer), 411.
— the Cause of Grave Exanthem (Schmey),
555.
Salophen in Pruritus (Wannemarker), 426.
Salve, Formula for Lip, 9.
Sandell Exhibition, The, 346a.
Sander, G. — Contribution to the Knowledge
of Strychnine Drugs, 245.
Sandys v. Simpson — Proceedings in the
Court of Appeal, 118.
Sanitary Towels, Cheaper, 263.
Sanitas Company, Limped, The Dairy Show
Exhibit, 20a.
— Disinfectant Soap, 484a.
Satchets, Advertising, 484a.
— Formulae for Perfumed, 493.
Saxin as a Sweetening Agent, 464.
Saxlehner v. the Apollinaris Company,
(Hunyadi Janos and Uj Hunyadi
Waters), 157, 195, 224a.
Scale in Boilers, To Prevent, 472.
Scammony, Note on a Sample of (Thomson),
245.
Scents and Cosmetics in China, The Trade
in, 426.
Schacht, George, Frederick, Editorial
Remarks on the Death of, 11.
— G. F., Memorial, The, 224a, 446.
— G. F. — Reminiscences of the School of
Pharmacy, 546.
Schering Chemical Works, Fire at the, 524a,
544a.
Scholarships, Three Pharmaceutical, 476.
School of Ethics for London, A, 517.
— of Pharmacy, Reminiscences of the
(Giles), 560 ; (Reynolds), 562 ; (Groves),
(A Student), 563.
— of Pharmacy, Class of 1896-97 (A Student),
563.
— of Pharmacy Students’ Annual Dinner,
215, 219.
— of Pharmacy Students’ Association, 118,
155, 258, 454.
Schulze’s Chlor-Zinc Iodine Solution, 366.
Schweppe’s Soda-Water and the Customs,
568a.
Science and Art Department, The, 242.
— and the Imagination (MacEwan), 258.
— Progress in, in 1896, 14.
— The Endowment of, 32.
Scopolamine as a Cerebral Sedative, 405.
Scotland, The Progress of Pharmacy in the
East of (Scottish Chemist and Drug-
gist), 555.
Scott, D. H. — The Present Position of Mor¬
phological Botany, 34, 360, 478.
— Dr. Alex. — On a New Series of Mixed
Sulphates of the Vitriol Group, 280.
— Dr. Alex. — On the Atomic Weight of
Carbon, 280.
Scupham, F. H.— The Regulation of Prices,
99.
Secretions in Plants, Formation of (Tschirch),
289.
Sections of Capsicum Fruits, How to Cut
(Flatters), 607.
Seeds, Latent Life' of (Candolle), 468.
[Supplement to
Pharmaceutical Journal.
Self-medication in Drug Stores, 558.
Sensitiveness, Mechanism of (Borzi), 370.
Seward, A. C. — Fossil Plants, 127.
Septal Nectaries (Schniewind-Thies), 167.
Shampoo, Egg, Formula for, 544.
Sharman, H. B. — The Council Election, 502.
Shaw, G. E. — The Alleged Conversion of
Cinchonine into Cinchonidine, 199, 286.
Sheffield College of Pharmacy, 224a.
— Pharmaceutical and Chemical Society,
95.
Shells, Peculiar Markings on (Monckton),
115.
Shenstone, W. A. — Studies of the Properties
of Highly-Purified Substances, 94.
Shoreditch Combined Electricity and Dust
Destruction Undertaking, 559.
Show Bottles, Formulae for Colours for, 306.
Sight, Book on Testing the, 464.
Signalling Through Space Without Wires
(Preece), 521.
Silver Changed to Gold (Emmens), 100a.
— Diphosphide (Granger), 467.
— Glass, Formula for Solution to, 544.
— Oxidation of (Wait), 81.
Silvering Tinware, Stockmeyer’s Process of,
493.
Sinclair, George — Progress in Pharmacy,
331.
Single Solution Developer, Formula for, 408.
Sixty Years Ago, Notes on Dispensing (Proc¬
tor), 553.
— Years of Progress, Editorial Remarks on,
536, 557.
— Years’ Progress in Chemistry and the
Chemical Arts (Thorpe), 511.
— Years, Pharmaceutical Development dur¬
ing, 545.
Smith, A. — The Dose of Tincture of Stroph-
anthus, 345.
— E. A,, and Jenkins, H. C. — On tho Reac¬
tions between Lead and the Oxides of
Sulphur, 423.
— F. L. — Note on Guaiacum, 101.
— John H. — Medicine Stamps, A Sugges¬
tion, 462.
— John — The Benevolent Fund, 119, 198.
— John — The Journal and its Students’
Page, 120.
— J. B.— The Ginkgo Tree, 137.
— (T. H.) and Co.’s Employes’ Outing, 524a.
— W. U. — Sulphuric Acid and its Manufac¬
ture, 96.
Snake-Bite Treated with Antivenomous
Serum, 33.
Snook, J. J. — The Regulation of Prices, 78.
Soap, Formulae for Essences of, 460.
— Making in Persia, 38.
— Manufactories in Greece, 461.
Soaps, (Vegetable (Davy), 371.
Social Scale, Editorial Remarks on the
Position of Pharmacists in the, 515 ;
(Glass), 543.
Society of Arts, 187.
Society’s Anniversary, Editorial Remarks on
the, 447.
Sulphate of Ammonia as a Fertilising Agent
in Java, 568a.
Soda Deposits of Wyoming, U.S.A., The
Natural, 568a.
Sodamide and some of its Substitution
Derivatives (Titherley), 187.
Sodium Bicarbonate as a Dressing
(Georgevsky), 457.
— Bicarbonate for Common Colds (Bulkley),
158.
— Chlorate in Uterine Cancer (Duvrac), 158.
— Chlorate, The Manufacture of, 366c.
••• Supplement to
XV 111 Pharmaceutical Journal.
Sodium Chlorate to Counteract Iodism (Calo-
meuopoulo), 58.
— Fluoride, 60.
— Hyposulphite for Parasites in Cattle, 417.
— Peroxide as a Group Reagent (Parr), 367.
— Telturate as an Anti-Sudorific in Phthisis
(Jo^uet and Neisser), 122.
_ Tetraborate iu Otorrhoea (Kafemann),
426.
Sol. Strontii Iodid. Paraf. Javal (Pharma¬
cist), 20; (Robertson), 39.
Soups, Solidified, 263.
South Kensington Chemists and the P. A T. A.,
224 a.
_ Kensington Museums, The Unprotected
State of, from Fire, 473.
— London School of Pharmacy, Smoking
Concert, 244®.
Spain, Imports of Drugs and Chemicals into,
during, 1896, 384.
Special General Meeting of the Pharmaceuti¬
cal Society, The, 437 ; (Taplin), 464^, 476.
Species-making, Philosophy of (Bailey), 84.
Specimen Bottles, Domed, 484®.
Spectral Analysis and Wave-Lengths
(Kayser), 81.
Spermatozoids from the Pollen Grain, 92.
Spirit Gum for Theatricals, Formula for, 346.
Spirits, Special Licence Required for Com¬
pounders of, 421.
Spurious Balsam of Tolu, A (Braithwaite),
307.
Squire, P. W.— Unguentnm Hydrargyri
Nitratis, 172, 244.
Standardisation, The Limitations of, 351.
Stannous Iodide, The Apparent Action of
Light in Inducing Crystallisation of
(Warden), 61.
Starch Gloss, Formula for, 100.
— Iodide, Formula for Ointment of (Oefele),
513.
Startin’s Face Lotion, Formula for, 326.
St. Cyr, E. L. N.— The Proposed New Bye-
Laws, 483.
Steam Bath, a Small, 74.
— Coils for Evaporation, On the Ute of
(Warden), 307.
— Distillation, An Improved Apparatus for
(Matthews), 134.
Steel or Brass Tubes, To Bend, 484, 504.
Stephens, H. P.,and Chattaway, F. D. — The
Hydrolysis of Perthiocyanic Acid, 320.
Steresol as an Application to Sore Nipples,
242.
Sterilisation of Catgut (Larrabee), 162.
Sterilised and Humanised Milk Factory
at Dunfermline, 516.
Steriliser, A Simple (Forret), 293.
Stevenson’s, Dr., Report on the Examina¬
tions, Remarks on, 318.
8* ill, Excise Duty for the Use of a, 160.
Stills, Excise Regulations respecting, 268.
Stipules, The Forms and Functions of, 300.
Stock on the Graft, Influence of the
(Rivihre and Bailbache), 299.
Storage and Pharmacy Arrangement, Some
Short Notes on, 476 ; (Hyslop), 481.
S'orrar, David — The Approaching Council
Election, 345.
Stratton, W. G.— Ferri et Quinines Citras and
Potassii Citras, 344.
Streatham, Balham, aDd Tooting Distiict
Chemists’ Association, 449.
Street Noises, Politicians and, 541, 556.
Strickland, E. J — The Brentford Lime Cream
and Glycerin Case, 503.
Strophanthus, The Dose of Tincture of
(MacNaught), 325; (Wilkinson), (Smith),
345.
INDEX.
Structure of Matter, Editorial Remarks on
the Inner, 151.
Strychnine Drugs, Contribution to the Know¬
ledge of (Sander), 245.
Students’ Page, The, 10, 30; (British Student),
40 ; 50, 54 ; (Ulster Student), (Jones),
(Ware), 60; 70; (Kemp), (J. P. K.),
(Barrett), (H. D. K.), 79; 90; (Quali¬
fied), (Cross), (Dyer), 99; 110; (Hick¬
man), (Smith), 120; 130, 150, 178, 182;
(Remarks on the S.P.), 215; 254,276, 296,
336, 356, 418, 474, 514.
Studies of a Pharmacist, The (Alcock),
380.
Sturch, Harry H. — Preserving the Colour of
Algre, 385.
Sub-Postmasters, Combination of Chemists
who are, 497.
Substances, Drying Sensitive Organic ( Par¬
sons), 465.
— Properties of Purified (Shenstone), 465.
Substitution, A Case of, in India, 236.
Subterfuge, UnearthiDg a, 120®.
Sugar for Chemists, 464®.
— Gravimetric, Determination of Invert,
484.
— Growing in the British West Indies,
Special Commission on, 8.
— Made in Germany, Prosecution for
Selling, 80®.
Sulphate, Hydroxylamine (Divers andHaga),
367.
Sulphates of the Vitriol Group, On a New
Series of Mixed (Scott), 280.
Sulphur Soap, Manufacture of, 493.
Sulphuric Acid and its Manufactura (Smith),
96.
Sulphurous Acid by Potassium Perman¬
ganate, The Oxidation of (Dymond and
Hughes), 187.
Sumbul, The Cultivation of, in England
(Holmes), 347.
Summers, S.— The Life and Work of Dr.
William Harvey, 155.
Sunderland Chemists and the P.A.T.A , 77.
Sundries, Novelties in, 464®,
Super saturated Solutions, Crystallisation
of (Ostwald), 465.
Suppositories and Their Manufacture
(Lewin), 411.
Suppository Mould, New, 406.
Surfeit Water for Horses, Formula for,
316.
S utherland, Alexander— Accuracy, 218.
— A’exander, Death of, 516.
— j. W. — The P.A.T.A. Meeting at Damfries,
80.
Swainson, G.— Corals and Coral Islands,
95.
Swansea Chemist’s Affairs, A, 92, 112.
Sweating the Dispenser (Ami-Sweater),
138 ; (Dispenser), 224 ; (Blad R. O’Lard),
(Anti-Sweater), 263, 264 ; (A.P.S.), 285 ;
(Dispenser), 305 ; (Anti-Sweater), 384 ;
(Dispenser), 428.
“Sweetbread,” The Different Organs Known
as, 379. '
“Sweet Lavender,” 52; (Perks andLlewellen),
59 ; 92.
Sycosis, Formula for an Application for,
425.
Synanthy in Dendrobium Brymerianum, A
Case of (Reynolds), 319.
Synthesis of Citric Acid (Laurence), 466.
Synthetic Perfumes, Some Formulfe for,
460.
Syphons, A Chemist Charged with Receiving
Stolen, 160®, 28 Gel.
Syrup Making without Heat (Wood), 79.
[July 3, 1897.
T
Tabloids, Compound Phenacetin, 8.
— Formula for Mouth-wash (Bernegan), 374.
— More New, 57.
— Pig Bile, 524®.
— Red Gum, 366u.
Tannigen in Diarrhoea (Hirschberg), 58.
Taplin, Wm. G.— The Special General Meet¬
ing, 464 d.
Tasker, W. A.— Some Suggested Improve¬
ments in the Rules of the C.A.A., 155.
Tayler, C. Ludlow — Ethyl Alcohol, Acetalde¬
hyde, and Acetic Acid, 300.
Teaching University, The Prospect of a Lon¬
don, 461.
Technical Education, Editorial Remarks on,
337.
— Education in Germany, Remarks on the
Progress of, 72.
Teeth, Use of Iron for Filling, 568.
Teetoral Drinks at Sheffield, Prosecution for
Selling, 56.
Telegraphy without Wires, Editorial Re¬
marks on, 515; (Preece), 521.
Telephones, Nickel in (Garrett and Lucas),
371.
Temperature, Measurement of High, 266.
Teneriffe Mineral Waters, 38,
Teratology, Remarks on the Study of Ex¬
perimental, 132.
Terpenes from Essential Oils, Removal of,
346.
Terrestial Globe, A Great, 93.
Tesla Coil, The (Practical Radiography), 63.
Test for Nitrites in Water (Barbet and Jan-
drier), 456.
Testing the Sight, Bx>k on, 464.
Tetraborate, Sodium, in Otorrhoea (Ka'e-
mann), 426.
T’nalleoquia Test, Modified (Hyde), 371.
Theft from a Chemist at Weston-super-
Mare, 56.
Therapeutic Activity of Drugs (La Wall),
288.
Therapeutics of Emergencies, The (Mac-
naughton-Jones), 188 ; (Barrass), 243.
Thermometers, Remarks on German, 279.
Thiselton-Dyer, W. T. — Cultural Evolution
of Cyclamen Latifolium Sibth, 340.
Thomas, G. L., and Young, Sydney— Some
Hydrocarbons from American Petro¬
leum, 238.
Thompson, Charles — “ A Personal Com¬
plaint,” Reply to, 160.
— C. — The Benevolent Fand, 198.
— C. — The Regulation of Prices, 59.
— C. J. S. — The Antiquity and History of
the Mortar, 267.
— I. W. — Note on a Sample of Scammony,
245.
. — J. R. — Determination of Mercury in
Ammonio-Mercuric Chloride, 117.
— Professor E. Symes — Bacteria and Disease,
85.
Thorpe, Professor — Sixty Years’ Progress in
Chemistry and the Chemical Arts, 511.
Threats to Commit Suicide, 537.
Thymol in Pertussis (Josias), 361.
Thyroid, Dangers of (Hessler), 426.
Tincture of Kino, Gelatinisation of, 464.
Tinware, Stockmeyer’s Process of Silvering,
493.
Titherley, A. W. — Sodamide and Some of Its
Substitution Derivatives, 187.
Titroles, German, 530.
Tobacco, A Book on, 503.
Toilet and Nursery Powder, Formula for 9
July 3, 1897.]
INDEX.
Supplement to
Pharmaceutical Journal.
XIX
Toilet Soaps and Perfumery (Bergmann and
Co.). 197.
Tolu, A Spurious Balsam of (Braithwaite),
307.
Tomatoes, Method of Preserving, 513.
Toms, Frederick — Metric Measures and Our
Old System, 68, 147.
Tondeur Developer, Formula for, 544.
Tonic Syrup, Formula for, 200.
Tooth Paste, Composition of a Non-gritty
Soluble (Frohmann), 417.
— Powder, Formula for Violet, 9.
Toothache, The Postal Administration of
Geneva and, 299.
Trade, British and German with the Niger
Coast Protectorate, 159.
Trade Interests, The Protection of, Editorial
Remarks on, 31.
Transfusion Tissue, The Origin of, 300.
Trichomes, Hairs which are not (Tieghem),
371.
Triphenamine and Prenamine (Limlhorst
and Langkopf), 530.
Tubercule Bacilli in Batter, Note on, 355.
Tuberculin (Koch), 367.
Tuberculosis, Gallinaceous Birds and (Lan-
nelorgue and Achard), 468.
— The Royal Commission on, 97, 137.
Turnbull, W. S. — The Proposed New Bye¬
laws, 325.
Turpentine for Burns (Maclnnes), 56.
— How to Treat Discoloured, 40.
— The Effect of, on the Ui inary Secretion,
386.
Typke and King — The Keeping Qualities of
Essence of Lemon, 120.
Tyrer, Mr. A., Death of, 215.
U
Ulster Pharmaceutical Association, 191.
Umney, John C. — The Commercial Varieties
of Fennel and their Essential Oils, 225.
Unguentum Hydrargyri Nitratis (Lucas),
121 ; (Squire), 172 ; (Maben), 223 ;
(Squire), 244 ; (Maben), 265.
United States Pharmacopoeia, Remarks
on the, 339.
Universal Trade Association (Detroit),
Remarks on the, 184.
Uranium Intensifier, Formula for, 408.
Urtica Urens as a Haemostatic (Solovieff),
43.
Y
Vaccination Question before Parliament,
97. 154, 376, 494, 556.
— to Counteract the Poisonous Effect of
Ricin (Cornevin), 445.
Vanillin, Note on (Gussmann), 82.
— Test for, 167.
Varnish, Brown, Formula for, 80.
— Mahogany, Formula for, 20.
— Oak, Formula for, 20.
— White Hard, Formula for, 80.
Varnishes, Formulae for Enamel, 464.
Vaughan, D. T. Gwynne — Morphology and
Anatomy of some Nymphaeacae, 216.
Vegetable Antitoxins, A Theory of, 152.
— Honeycomb, A, 20c.
— Ointment Case, The, 56.
— Soaps (Davy), 371.
— Tissue Systems, Histology of the
(Morison), 470.
Viburnum Prunifolium (Franqois), 290.
Victoria, The Pharmacy Board of, 449.
— Violets Perfume, 366c.
Vinum Colebici, Note on (Cowley), 173.
Violet Perfume, Formula for, 460.
— Too h Powder, Formula for, 9.
Viscum, Fruit and Seed of (Gjokie), 289.
Vitellin Creme (Bernegan), 530.
Vitriol Group, On a New Series of Mixed
Sulphat s of the (Scott), 280.
Vivisec ionists and Mr. Swift McNeill, 262.
Vizer, Edwin B. — The Proposed New
Bye-laws, 428.
W
Warden, C. J. H. — A Drying-box for Pills,
etc., 245.
— C. J. H. — On the Apparent Action of
Light in Inducing Crystallisation of
Stannous Iodide, 61.
— C. J. H. — On the Separation of Nitrate of
Copper from Nitrate of Silver in the
Manufacture of Caustic, 61.
— C J. H. — On the Use of Steam Coils for
Evaporation, 307.
Ware, Alan H. — The Students’ Page, 60.
Warrell, E. — The Sale of Food and Drugs
Act, 264.
Water Divining, Costly Faith io, 497.
— Gas, Preparation of, 120.
— The Presence of, and of Alcohol in
Chloroform (Behai and Frarxjois) 465.
Wave-Lengths, New Law of (Runge and
Paschen), 81.
— -Lengths, Spectral Analysis and (Kayser),
81.
— -Motor, A, 54.
Waves, The Physical Properties of Electric
(Bose), 102.
Weather Signs and Fallacies (Whitmore),
469.
Webber, J, W.— The Brentford Lime Cream
and Glycerin Case, 483.
Weighing Flask, A New (Heath), 290.
Weights and Measures, British, 10, 242.
— and Measures, Our (Chaney), 84.
Wells, Sir Spencer, Death of, 112.
Welsh, John — Dispensing Difficulty, 300.
Western Chemists’ Association (London),
100a. 156, 259, 386a, 481, 537.
Whale Oil in Acne (Boeck), 158.
White Embrocation, Formula for, 346.
— Hard Varnish, Formula for, 80.
— Heliotrope, Formula for, 306.
Whooping Cough, Formula for Em¬
brocation for, 9.
Whysall, W. — Chemists and Company,
Legislation, 38.
Wild, Dr. Robert B. — Living Tissues as
Chemical Reagents, 125.
Wilkinson, W. — The Dose of Tincture of
Strophanthus, 345.
— - W. — The Formation of the Manchester
Pharmaceutical Association, 19.
Williams, Miss K. J. — The Composition of
Cooked Fish, 320.
Wilson, Dr. T. — Doctors and Medicine Mer
135.
— Dr. W. Cheyne — Rontgen Rays, 218.
Wine, Artificial, 502.
— Formula for Meat, Malt, and Quinine,
524.
— Growing in Eagland, Experiments by
Lord Bute, 421. g ,AAnaj>j]
— Licences, Chemists’, 464(7. *
Win er-green Plants (Lidforss), 83.
Wokes, T. S. — Dispensing Experience|with
Feiri et Quininse Citras and Potass as
Citras, 321.
Woman Chemist, Remarks on a, 73.
Wood, E. M. — Ferns, 135.
— Sir Henry Trueman — The Production
of Colour by Photographic Methods,
187.
Wood That will not Burn, 46 id.
Woolfat, Chemistry of (Darmstaedter and
Lifschiitz), 369.
Worms in Poultry, Powder for, 346.
Wounds, The Treatment of, by Oxygen Gas,
477.
Wren’s Nest in a Rook’s Body (Harting), 216.
Wright, R., and Farr, E. H. — The De¬
termination of Alkaloids, Notes on Some
of the Pharmacopceial Processes, 202.
Wyatt, Harold, jun. — More Dispensing
Notes, 464c.
X
X-Crystals, 4646.
Xeroform as a Dressing (Beyer), 522.
X Ray Photographs of the Solid Alloys
(Hevcock), 423.
— Ray-Tubes, Condensers and (Norton and
Lawrence), 290.
— Ray -Tubes, the Efficiency of, 422.
— Rays, Action of (Sabrazes and Riviere),
469.
— Rays, Kathode and (Swinton), 371.
Y
Yeast, Ferment from (Buchner), 288.
— Manufacture of, 83.
Yellow Fever, The Bacillus of, 80a.
Young, E. F. — The Society and the P.A.T.A.,
543.
— Sydney and Thomas, G. L. — Some
Hydrocarbons ft om American Petroleum,
238.
Z
Zinc-Copper Couple, Improved (Stock), 290.
— Oxide and Belladonna in Whooping
Cough, Formula for, 58.
W. I. Richaedson, Peinteb, 4 and 5, Geeat Queen Steeet, Lincoln’s Inn Fields, London, W.C,
XX
Supplement to
Pharmaceutical Journal
.]
INDEX.
[July 3, 1S97.
CONTRACTIONS OF TITLES.
The following is a list of the contractions and the corresponding full titles of Journals most frequently used in “ The Month"
and elsewhere in the “ Pharmaceutical Journal." The titles prefixed by an asterisk (*) are those of official Journals.
Amer. Journ. Pharm. = American Journal of Pharmacy. Phila¬
delphia. Monthly.
Annalen — Justus Liebig’s Annalen der Chemie. Liepzig. Monthly.
* Apot.-Zeit. = Apotheker-Zeitung. Organ of the Deutsche Apothe-
ker-Verein. Berlin. Twice a week.
* Apot. Zeit. Rep. =Repertorium der Pharmacie. Supplement to the
Apotheker-Zeitung.
* Archiv—Axchxw der Pharmacie. Berlin: J. Greiss. Monthly.
* Berichte = Berichte der deutschen chemischen Ges611schafr.
Berlin. Once or twice a month.
* Brit. Med. Journ. = British Medical Journal, London. Weekly.
Bull. corn. = Bulletin commercial. Supplement to L’union pharma-
ceutique. Paris : Pharmacie centrale de France. Monthly.
* Can. Pharm. Journ. = Canadian Pharmaceutical Journal. Toronto.
Monthly.
Chem. News = Chemical News. London. Weekly.
Chem. Zeit. = Chemiker Zeitung. Cothen. Twice a week.
Chem. Zeit., Rep. = Chemisches Eepertorium. Supplement to the
Chemiker Zeitung.
* Comp. rend. — Comptes rendus des seances de l’Acadjjmie
des Sciences. Paris : Gauthier-Villars. Weekly.
* Journ. Chem. Ind.— Journal of the Society of Chemical Industry.
Monthly.
* Journ. de pharm. — Journal de pharmacie et de chimie.
Paris : G. Masson. Twice a month.
Med. Press = Medical Press and Circular. London: A. A. Tindall,
Weekly.
Mon. sclent. = Moniteur scientifique. Paris. Monthly.
Munch, med. Woch. — Miinchener medicinische Wochenschrift.
Munich. Weekly.
Nouv. rem. = Les nouveaux remedes. Paris. Twice a month.
Pharm. Centralli. = Pharmaceutishe Centralhalle Dresden. Weekly.
Pharm. Post = Pharmaceutische Post. Vienna. Weekly.
Pharm. Zeit. = Pharmaceutische Zeitung. Berlin : J. Springer.
Twice a week.
* Proa, Chem. Soc. = Proceedings of the Chemical Society. London.
About twice a month.
Repertoire — Repertoire de pharmacie, archives de pharmacie
et journal de chimie medicale reunis. Paris. Monthly.
Sclent. A m er. — Scientific American. New York. Weekly.
Union pharm. = L’union pharmaceutique. Paris : Pharmacie
centrale de France. Monthly.
THE
ARMAGEUTI
VOLUME LVIII. (Fourth Series, Volume IV.)
LONDON : SATURDAY, JANUARY 2, 180
Pharmaceutical Progress in 1896.
' HE events of the past year bearing upon the business
of the chemist and druggist have been even less
important than those of immediately preceding years.
The administration of the Pharmacy Act has been con-
tinued with some advantage, though the prosecution
of offenders is attended with considerable expense and risk of failure,
besides having, in some instances, other obstacles to contend with.
The breach in the Pharmacy Act by which an association of unquali¬
fied individuals is enabled to carry on the business of a chemist
and druggist has now been considerably widened, and practi¬
cally the application of the principle of limited liability
has been so far extended beyond the mere monetary affairs of
trade, that a person without pharmaceutical qualification can secure
immunity from the operation of the law relating to the practice of
pharmacy by a formal compliance with the technical conditions
requisite for constituting a company. The hope that amendment
of the Companies Acts might furnish a remedy for this anomalous
state of affairs has not yet been realised, and while the magnitude of
the interests involved in company trading appears to be an obstacle
to reform, it has also had the effect of completely overshadowing
the evils inflicted upon chemists and druggists by misapplication of
the Companies Acts.
At the meeting in January the President
The Work drew attention to the fact that chemists’ branch
of the shops are not always carried on under the con-
Couneil. ditions which the law requires, and he suggested
that local secretaries should take cognisance of
such cases in order to obviate the difficulty in which the Council
might be placed when information came to it — as the administrator
of the Pharmacy Act — that registered chemists were not conducting
their business in strict conformity with the law. He held that it
was the duty of every person on the Register to comply with the
law, and that the endeavour to put those right who, perhaps inad.
vertently, failed to do so, would be a greater kindness than to come
forward and ask for clemency when such instances were made known,
sometimes from public sources. By that means the Council would be
assisted in the performance of its duty of enforcing the law and also
saved from appearing to do so harshly. These remarks were, in the
main, endorsed by Mr. Bottle and Mr. Hills.
In connection with the presentation of the Registrar’s report at
the February meeting (see p. 106), Mr. Bottle expressed regret that
chemists did not rally round the Society as he thought they
should do in their own interest. He hoped before long that the
Council would be enabled to elect as members many of the younger
element who joined the Society as Associates. Mr. Allen pointed
out that the larger proportion of those passing the Major examina¬
tion joined the Society or were attached to it before passing, and
Mr. Hills mentioned that according to the report then
Vol. LVIII. (Fourth Series, Vol. IV.). No. 1384
presented, fifty-seven out of sixty-eight Major men had
joined the Society. Before passing a resolution to make a grant
to the Liverpool Pharmaceutical Students’ Association, a long
discussion took place on the subject of assisting the education
of students in provincial centres, in the course of which the
want of a definite curriculum was referred to as a great obstacle to
educational improvement, since apprentices were not made aware of
what they would have to learn in order to become qualified. General
approval was expressed of the facilities for study now afforded at
Liverpool, Bristol, Newcastle, and other centres, and the desirability
of aiding schools of that kind was recognised. At this meeting of
the Council a communication was read from the Glasgow and West
of Scotland Pharmaceutical Association, expressing approval of the
remarks made by the President at the January meeting on the
subject of unqualified managers of branch shops.
At the meeting in March a sub-committee was appointed to watch
the progress of business in Parliament, and take such steps as might
be necessary in regard to any measure affecting the trade. A long
discussion took place on the subjects of the Companies Bill and the
Early Closing Bill, in which opposite views were expressed in
reference to the latter measure, the President pointing out the
advantage of having the ear of the Government when legislation
affecting chemists and druggists is in progress, and the desirability
of encouraging every effort tending in that direction.
On the presentation of the Government visitor’s report on ex¬
aminations at the April meeting, the President drew attention to
the remarks made upon the Preliminary examination as indicating
that the standard of that examination should be raised and
made more applicable to the purpose it is intended to serve.
The desirability of taking steps to that end was fully
recognised.
A communication from the Inverness Chemists’ Association was
read, informing the Council of the action taken by that body in
reference to the Companies Bill, and the President reported the
general result of the interview between the “ Watch ” Commit¬
tee and the President of the Board of Trade on that subject.
A resolution, passed by the Western Chemists’ Association of
London, deprecating the prescribing of proprietary medicines, was
referred to the General Purposes Committee for consideration, as well
as another communication from the Glasgow and West of Scotland
Pharmaceutical Association, relating to some decisions in Scottish
law courts in prosecutions under the Pharmacy Act.
A letter from the Local Secretary of a large city was also
read, pointing out the desirability of removing the inequalities in
the position of Members and Associates of the Society, and urging
that qualification under the Pharmacy Act should constitute
eligibility for membership of the Society. Mr. Warren took the
opportunity on this occasion of stating that since the time when
he had expressed doubt on this point further consideration had
convinced him that he had been mistaken, and he now thought
that every inducement should be offered for bringing all registered
chemists into the Society.
2
PHARMACEUTICAL JOURNAL. *
[Jan. 2, 1897
At the meeting in May the report of the Executive of the North
British Branch of the Society was presented, showing that the
extension of the Society’s premises in Edinburgh bad facilitated
the conduct of the examinations and given general satisfaction.
At the opening of the June meeting the chair was taken by Mr.
Carteighe, who offered a welcome to the new members, Messrs.
Bateson, Park, and Symes. On the ballot being taken for the
election of President all the votes were in favour of Mr. Walter
Hills, who in taking the chair expressed his sense of the onerous
nature of the duties appertaining to the position, and of the
additional difficulty that arose in following a president who had
for many years occupied that position with unparalleled
ability. Relying upon the assistance of his colleagues, he trusted
they would he able to accomplish something useful for the
common good. In the ballot for Vice-President Mr. Harrison was
re-elected, and in thanking the Council for the renewed proof of
confidence, he took the opportunity to assure the President, on
behalf of his colleagues, that the support he looked for would be
fully and freely accorded. Mr. Hampson was re-elected Treasurer,
and Mr. Richard Bremridge was re-appointed Secretary
and Registrar.
The President then moved a resolution of thanks to Mr. Carteighe
for the invaluable services he has rendered to the Pharmaceutical
Society as President during fourteen years, in order to place on
record the Council’s appreciation of his self-sacrificing devotion and
loyalty to the interests of the Society. This was seconded by the
Vice-President and carried with acclamation.
At this meeting a resolution was passed that the seal of the
Society should be affixed to the document authorising the Bank of
England to pay the dividends on the stock purchased for the
Burroughs Scholarship. Mr. Carteighe reported that the
Sab-Committee charged to consider the relations of the
Society to the School of Pharmacy and its general scheme
of education recommended that in future the teaching of
chemistry should be entrusted to one person, who should also
be the Director of the Research Laboratory. That recom¬
mendation was adopted by the Council, and the Committee
was authorised to communicate with Professor Attfield on the sub¬
ject, the result being that he placed his resignation in the hands of
the Council, and the Committee recommended that it should be
accepted. A further recommendation was that the Council should
again take control of the Laboratory, as in former years, and that
the Professor appointed should devote his whole time to the duties
of his office. The adoption of these recommendations of the General
Purposes Committee was moved by Mr. Carteighe, seconded by Mr.
Martindale, and carried unanimously. Mr. Carteighe then moved that
the cordial thanks of the Council be given to Professor Attfield for
the services he had rendered to the Society during the thirty-four
years he had held the distinguished position of Professor of
Practical Chemistry in the Society’s School, supplementing the
motion with an account of the Professor’s past connection with
the Society’s School, and with wishes for his future welfare and
happiness. The motion was seconded by Mr. Hampson and carried
unanimously.
At subsequent meetings of the Council the arrangements relating
to the conduct of the School of Pharmacy were finally confirmed.
At the meetings in November and December the subject of the
appointment and duties of local secretaries gave rise to a long dis¬
cussion, and eventually it was referred to the General Purposes
Committee for consideration. The opinions expressed in the
discussion were generally in accord with the remarks made by Mr.
Barnitt, of Leamington, at the annual meeting, as to the desirability
of placing local secretaries more closely in touch with the Council,
and the same view has since been put forward in a letter from Mr,
Bostock, of Ashton-under-Lyne.
The report presented by the Council at the
The Annual anniversary meeting in May showed a con-
Meeting1. siderable increase of expenditure, partly on
. account of the new premises in London and
Edinburgh, partly also on account of law charges and of the
Society’s Journal, while the income from fees was less than in the
previous year. The details given of the work done by the
Society, in its private capacity, in maintaining museums and
libraries, the School of Pharmacy, and the Research Laboratory,
showed that progress had been made in each department.
The subscriptions to the Benevolent Fund had been a few
pounds less than in previous years, but the substantial sum
of £2693 had been expended in grants and annuities. In the
Society’s public capacity, as the examining body authorised to
test the “competent practical knowledge” of persons intending to
carry on business as chemists and druggists, the attainment of that
object was shown to have been promoted by the recently extended
scope of the qualifying examination, but the Preliminary examina¬
tion was referred to as being in great need of amendment. The
expenditure on prosecutions for infringement of the Pharmacy Act
was, as usual, far in excess of the costs allowed, leaving a consider¬
able adverse balance. In most of the cases tried judgment was
given for the Society, either in the first instance or on appeal, but
some difficulty was experienced in Scotland, either in consequence
of the views held by the Sheriffs and Procurator Fiscal, or apparent
sympathy with the defendants. As a result of the action taken by
the Society in regard to the patenting of medicines containing
scheduled poisons there had been need to take legal proceedings
only in three instances, and in those there was no serious defence.
In addressing the meeting, Mr. Carteighe expressed the opinion
that, large as the capital expenditure had been, there was no neces¬
sity for its continuance, nor any reason to anticipate danger of the
Society’s work being restricted in future on that account. That-
view of the matter was very generally adopted by the meeting,
which might have been more than usually uneventful had not Mr-
Whitfield directed attention to the state of the Society’s School as
compared with that existing when he was a student. His speech
on that subject produced considerable effect and though it was not
commented on by anyone present, it may be assumed to have exer¬
cised considerable influence upon the Committee which had under
consideration the relations of the Society to its educational work
and to the School. The recommendations subsequently made to the
Council and the further consequences of their adoption, may
perhaps be regarded as directly due to the action of Mr. Whitfield,
at the annual meeting.
The periodical reports of the Committee con-
Benevolent ducting the business of administering the Fund.
Fund. for the relief of distressed members of the
trade, and of their widows and orphans, have
continued to give frequent evidence of the interest taken in this,
branch of the Society’s work, by recording the receipt of donations
and legacies. The subscription to the Fund has not been so welL
maintained, and it is still far from being so general as might be
expected, or sufficient in amount to enable the Committee to meet
all the applications which bear investigation. Considerable assist¬
ance has been given in the form of occasional grants in many
instances during the year, and at the January meeting of CounciL
the President expressed his satisfaction at finding the Committee
recommending the grant of respectable sums that were likely to be
serviceable. But such a generous policy requires corresponding
support from subscribers.
Jan. 2, 1897.]
PHARMACEUTICAL JOURNAL.
3
The statistics for 1896 lead to the convic-
Examinations. tion that pharmacy has not yet reached such a
stage of decadence as to be numbered with
unattractive callings. The fact that the number of entries in 1896
for the First examination shows an increase of 103, and the number
for the qualifying examination a rise of 145, may be taken
as a proof that the pessimism which contends with lugubrious
persistency that pharmacy is “ going to the dogs ” is not taken very
seriously by the rising generation. In the following table the
entries and rejections in the Minor examination during the past
three years are compared, and the comparison is instructive: —
Minor Examination.
Year.
Entries.
Rejections.
Percentages of
Rejections.
London.
Edin.
London.
Edin.
London.
Edin.
1S94 .
970
440
626
260
64-53
59-09
1895 .
819
485
574
2S3
70-OS
58-35
1896 .
793
656
533
413
67-21
62-95
Perhaps the most noteworthy circumstance disclosed in this
table is the growing popularity of Edinburgh as a centre for
examination. It would seem, therefore, that the additional
examination accommodation provided by the Council at York Place
has been promptly taken advantage of by English candidates
residing in the counties near the border. How far the largely
enhanced attractiveness of the northern capital to Minor candidates
in 1896 was related to the low percentage of rejections recorded
for that centre in 1895 there is happily no need to discuss ;
but if any “unprepared” man went across the Tweed
in the hope of finding the statutory test of pharmaceutical
competency less stringent there than in London, he must
have been badly disillusioned, and sent to join the ranks
of those who have raised the percentage of rejections in
Edinburgh from 58-35 to 62'95. Taking the candidates for the
Minor as a whole, the rejections gave a similar percentage to that
experienced in 1895, that is to say a little over 65 per cent.
For the Major examination there have been fewer entries than in
1895, the actual numbers being 130 as against 146. A continuous
diminution has thus been shown in the returns for the past four
years, and this appears significant of modern conditions
operating against academic tests which confer no immediate
tangible reward upon those successfully submitting to them.
The following comparison of entries and rejections for
the last three years reveals no very satisfactory decrease in the
proportion of failures, though there is a slight move in the right
direction. 53-07 per cent, is, however, a higher rate of rejection
than might be reasonably looked for among persons who have been
through the severe ordeal of the Minor examination.
Major Examination.
Year.
Entries.
Rejections.
Percentages.
1894 .
147
73
49-66
1895 .
146
78 ■
5342
1S96 .
130
69
53-07
TheFirst examination in 1896 proved too difficult for 829 candidates
out of 1533, a percentage which is not encouraging to those who
believe that a sound elementary training in arts is a sine qud non to
pharmaceutical success.
First Examination.
Year.
Entries.
Rejections.
Percentage.
1894 . .
1541
788
51-13
1895 .
1430
753
52-65
1896 . .
1533
829
54-07
As the First examination is now on its trial before a Committee
of the Council of the Society, there is ground for hope that before
long some radical change may be brought about in the method of
ascertaining the mental calibre of youths contemplating entering
upon a pharmaceutical career.
From a pharmaceutical point of view the
Parliamentary, pastyearhas been singularly barren inparlia-
and mentary' results, yet it may be said with
Legal. truth that few sessions since the passing
of the last Pharmacy Act have seen
the Society so politically active as that which closed in
August last. It may be remembered that early in the year
a Sub-Committee of the Law and Parliamentary Committee
was appointed to watch the course of public business, and
there was certainly sufficient on the Journal of the House
of Commons to justify the appointment. Legislation was
expected in the direction of amending the law relating
to food and drugs, weights and measures, the sale and storage of
petroleum, and the formation and registration of limited liability
companies, in each of which Acts, it was contended, grave defects
existed. With questions of this nature coming within the range of
practical politics and affecting, either directly or indirectly, the
interests of chemists and druggists, it behoved the Council to ensure
by some means or other the recognition and, if possible, the accept¬
ance of pharmaceutical views. Though the Society’s efforts in this
direction may not have secured any very brilliant triumph, there is
no real cause for discouragement.
Perhaps the measure of most vital importance was the Bill to
amend the Companies Acts, introduced by Earl Dudley into the
House of Lords on March 19. By the efforts of the Society, acting
in conjunction with representatives of the Medical, Dental, and
Veterinary professions, a clause protecting personal professional
titles from abuse by impersonal corporations of unregistered
individuals was sought to be added to the Bill. The amendment
had the high sponsorship of Lord Herschell, and would no doubt
have been embodied in the measure, if fate had not ordained
that the Session of 1896 should be a unique period of legis¬
lative congestion. The Bill was read a second time, and referred
to a Select Committee, from which it never emerged. The Committee is
to be re-appointed early next session, when it is possible that the
significant decisions recently delivered in the House of Lords in
re Salamon and in the Queen’s Bench Division in re Wragg, may
stimulate in the individuals comprising the Committee a desire to
remove at the earliest possible moment the legal shelter for so
much commercial unscrupulousness. According to the Lord Chan¬
cellor, the present law as to incorporation cannot take into account
motives : — “The motives of those who take part in the promotion
of the company are absolutely irrelevant in discussing what its
rights and liabilities are.” “Register! Register! Register!” thus
seems to be the most profitable motto for adoption, if it is desired to
escape the personal obligations and responsibilities which weigh
upon individuals.
As regards the Sale of Food and Drugs Act, although no amending
Act has been placed upon the Statute Book, the report of the Select
Committee of inquiry into the subject has made certain recom¬
mendations calculated to remove much of the ground for complaint
4
PHARMACEUTICAL JOURNAL.
[Jan. 2, 1897
existing under the present Act. The establishment of a Board of
Reference, to which all matters relating to standards should be
relegated, and on which a representative of the Pharmaceutical
Society should have a place, is among the satisfactory
recommendations contained in the Report. Whether those
recommendations will pass into an enactment during the
coming session depends upon fate and the Opposition. The
attempts of the Board of Trade to legalise the metric system
of weights and measures in Great Britain culminated in the intro¬
duction of a permissive Bill in July. It never reached its second
stage, and, indeed, was only brought in tentatively as a kind of
“feeler” to ascertain the general views of the commercial com¬
munity as to the system. The support of assistants in shops has
been very largely sought after by members of Parliament, and no
less than three measures for the limitation of the hours of em¬
ployment have been introduced. Sir J. Lubbock, Mr. Duncomb,
and Mr. J. Burns have each different views as to the ideal way of
dealing with the question, and each ideal has been embodied in
ideal Bills. All shared a common fate last session. Our readers
have been kept fully conversant of parliamentary matters affecting
chemists by the publication of weekly notes under the heading of
“ Parliamentary Notes and News.”
Under the Food and Drugs Act several important questions have
been raised. That relating to the use of preservative substances
still remains undecided, opposite decisions having been given in
reference to the use of salicylic acid for preserving orange wine and
ipecacuanha wine. The use of copper salts for preserving the green
colour of peas has been held to constitute an offence. The sale of
seidlitz powders differing in weight from that specified in the
British Pharmacopoeia has also been held to be a breach of the law. On
the other hand, in a prosecution for the sale of beeswax alleged to
contain paraffin it was held that when sold for other than medicinal
purposes beeswax is not to be regarded as a drug or as coming
within the scope of the Act. Quite recently prosecutions have been
instituted for the sale of “ arsenical soap ” alleged not to contain
arsenic, and in two very similar cases opposite decisions have been
given. Other cases are still pending.
During the year nearly 400- cases of alleged
Pharmacy infringement were reported and investigated.
Act. The necessary legal evidence having been ob¬
tained many of these cases were placed in the
hands of the Society’s solicitors for the institution of proceedings,
and as a result the majority of the offenders deemed discretion the
better part of valour, and paid the penalties claimed without the
cases going into court.
Littler ( Ph . J., January 11). — The first case heard in open
court was that at Rhyl, where a grocer, who had sold two bottles
of Mrs. Winslow’s soothing syrup, was sued for two penalties in
respect of keeping open shop for the retailing of poisons.
Defendant admitted being unqualified, but stated that as he had
a licence to sell patent medicines, he thought he was within his
rights in selling the article. In giving judgment, Sir Horatio
Lloyd expressed the opinion that the quantity of poison in the
bottle did not enter into the question. The moment it was proved
to him that an unqualified person sold any of the poisons mentioned
in the Schedule of the Act or any preparation of them, he is
proved to have committed an offence against the law, and renders
himself liable to penalties which there was absolutely no power to
reduce. Judgment must therefore be entered for the penalties
and costs.
Peacock (Ph. J., January 18). — The next case was that of an
unregistered person who kept a drug store at Hull and had sold a
preparation which he described as “ Mother’s True Friend,” and
which upon analysis was found to contain morphine to the extent
of l/3rd of a grain per ounce of the mixture. The defendant
admitted that he had paid penalties for the sale of the same article,
but stated that since the last payment he had reduced the quan¬
tity of the morphine. The case having been clearly proved, His
Honour Judge Bedwell gave judgment for the penalty claimed and
costs.
Walton, Hassell, and Port ( Ph. J., January 25). — An
important case was that heard at the Bloomsbury County Court on
January 21, in which a firm of oilmen were sued for a penalty
in respect of a sale of Mather’s chemical fly-papers, containing
arsenic. An eminent counsel was engaged for the defence, and
the case was keenly contested. A join analysis had been made and
it was proved that some of the fly-papers contained as much as
1 1 grains of arsenic. Expert evidence was given to prove that
there was sufficient arsenic in one paper to kill at least six people,
and that it was a simple matter to extract the poison from the fly¬
papers. For the defence an endeavour was made to prove that
there was arsenic in wall papers and other commercial articles in
use in this country. Objection was taken to this line of argument
and the Judge refused to allow it to be put in evidence, and in
giving judgment for the penalty and costs held that it had been
abundantly proved to him that the pores of these fly-papers were
filled with arsenic, or a preparation of arsenic. It being a test
case leave was given to appeal to the higher courts, but the appeal
was not proceeded with.
Ager (Ph. J., January 25). — In the same court and on the same
day an unregistered person was proceeded against for selling pare¬
goric. Defendant’s solicitor said he could not contend after the
decision just given that paregoric was not a preparation of opium,
but his client was an old man who had been a dispenser at two
hospitals. The judge held that this was no defence, and gave
judgment for the amount claimed with costs.
Symington and Thwaites (Ph. J., February 22). — At Market
Harborough Count}' Court a penalty was recovered from a firm of
grocers, who had sold a bottle of Fellows’ syrup of hypophosphites,
which was proved to contain strychnine.
Bainbridge (Ph. J., February 29). — In a case heard at the
Liverpool County Court, an unqualified assistant in a pharmacy
admitted selling a preparation containing opium, and an order
was made for payment of the penalty imposed by the Statute with
costs.
Savage (Ph. J. , May 2). — At the Bradford County Court an
unqualified assistant was sued for selling Powell’s balsam of aniseed
containing morphine. For the defence an attempt was made to
prove that a qualified man was in the shop at the time of the sale,
but the evidence in support of this statement broke down in cross-
examination, and the J udge held there was no doubt the defendant
sold the poison, and gave judgment accordingly.
Thorne (Ph. J., May 9). — At the Clerkenwell County Court a
medical student was sued for keeping open shop for the sale of poisons,
and evidence of the purchase of laudanum on two occasions was
given. For the defence it was admitted that the defendant was not
qualified, and that he kept a surgery, but it was denied that the
surgery was an open shop, or that any poison was sold. In
reviewing the evidence his Honour said that nothing could be
clearer than that this was a shop where anything was sold to
persons who chose to buy. The case had been clearly proved, and
he gave judgment for the penalties claimed with costs. Leave to
appeal was refused on the ground that it was quite a matter of
fact.
Fox (Ph. J., May 16 and June 20). — The most important case
during the year was that heard at the Westminister County Court,
Jan. 2, 1S97J
PHARMACEUTICAL JOURNAL*
5
in which a grocer was proceeded against for selling a bottle of
Kay’s compound essence of linseed, which admittedly contained
morphine. The point of the case turned upon the construction to
be placed on the exemption created in Section 17 of the Pharmacy
Act, 1868, in favour of patent medicines. The compound in question
was patented in 1873, but owing to non-payment of fees the patent
expired in 1876. For the defence in was argued that if an article
is once a patent it is always a patent within the meaning of the
section. Mr. Lumley Smith decided that at the time the compound
was sold there was no patent for it in existence, and therefore it
had ceased to be a patent medicine, and did not come within the
exemption created by the Statute. Having regard to the importance
of the case he allowed leave to appeal. This appeal was heard
before Mr. Justice Cave and Mr. Justice Wills in the Divisional
Court, and without calling on the Society’s counsel they dismissed
the appeal with costs.
Sinclair ( Ph . J. , June 20). — At the Greenwich County Court an
unqualified manager of a branch shop, who was proved to have sold
laudanum, pleaded that he had not sold the poison apart from the
jurisdiction of his master, but the Judge informed him that the
point had already been decided by the High Court, and he had
therefore no alternative but to give judgment for the penalty, with
costs.
Brade ( Ph . J., June 20). — An unqualified assistant in the em¬
ploy of a limited company was sued for two penalties at the
Blackpool County Court for selling Winslow’s Soothing Syrup.
Defendant did not appear, but the case was fully proved, and
judgment was given for the penalties and costs.
Blakeley (Ph. J., July 18). — At the King’s Lynn County Court
an unregistered person was sued for keeping open shop for retail¬
ing poison. Evidence of the sale by him of laudanum having
been given, his Honour gave judgment for the penalty imposed
by the Statute with costs.
Dickinson (Ph. J., July 25 and August 22). — At the Durham
County Court an unqualified assistant was proved to have sold a
bottle of Powell’s balsam of aniseed containing morphine, and
the usual penalty was imposed with costs.
Ryott (Ph. J., July 25). — At the same court another unquali¬
fied assistant, who had paid into the court the penalty claimed on
the day previous to that fixed for the hearing of the case, was
ordered to pay costs.
Douthwaite ( Pit. J., August 1). — At the Sheffield County
Court, the unqualified keeper of an open shop who had previously
paid penalties, was charged with three offences — two in respect of
the sale of poisons, and one for using the title “ Chemist.” For
the defence it was suggested that the defendant was not the
keeper of the open shop. His Honour held that the offences had
been fully proved, and gave judgment accordingly.
Burgon (Ph. J., August 29). — A few weeks later at the same
court and the same Judge a firm of grocers were sued for selling
Teasdale’s chlorodyne on two occasions. Several technical objec¬
tions were raised in the defence, which were, however, over-ruled
by the Judge, who, in giving judgment for the penalties claimed,
said he did so with infinite regret, as he did not believe there was
any intention on the part of the defendants to lead persons to
believe that they were chemists. A long argument ensued on the
question of costs, and the matter was adjourned for consideration.
At a subsequent court his Honour stated that he found there was
no power for him to refuse costs to the plaintiffs.
Meek (Ph. J., August 8).— The sale by a naturalist of an insect
killing bottle containing cyanide of potassium was the subject of
an action at the Brompton County Court. The Judge held that it
was a sale of cyanide of potassium, and gave judgment accordingly.
Mendel (Ph. J., October 24). — At the Lambert County Court
an unqualified person was sued for keeping open shop for retailing
poisons, andfor using the title ‘ ‘ consulting chemist.” Two purchases
had been made, one of oxalic acid, the other paregoric, but on the
latter being analysed it was found to be destitute of opium. His
Honour in giving judgment said the case was of serious importance.
Not only had the defendant sold poison, but he had called himself
a consulting chemist, which meant that he was a competent
chemist. In addition to these offences, he had sold what was
supposed to be paregoric, but which it appeared did not contain
the most essential ingredient of the medicine, which if bought for
the purpose of administering to a person in a case of illness
might by reason of its not containing what it ought to contain
result in very serious consequences. The Statute was a very
important one indeed for the protection of the public, and he
ordered the penalties to be paid with costs on the higher scale.
Potton (Ph. J., October 31). — An illustration of the difficulty
experienced in satisfactorily carrying out the provisions of the
Statute may be cited in the case heard at the Bow County Court,
where an unregistered person was sued for selling rat cake. The
sale was admitted, and it was proved that there was sufficient
arsenic in the cake purchased to poison 500 people. His Honour
Judge French, whilst characterising the offence as a most serious
one, ordered the penalty and costs to be paid at the rate of Is. per
month.
Marston (Ph. J., December 26).— At the Bournemouth County
Court an unqualified managing director of a limited liabilty
company was sued for a penalty in respect of selling chlorodyne
containing morphine. The sale having been admitted, his Honour
Judge Philbrick, in giving judgment for the penalty and costs,
said it was most important that traders and the public should
understand that poisons could only be sold by duly qualified
persons.
Sleight Pratt (Ph. J., May 2 and December 5). — A case was
heard at Leeds and another at Barrow-in-Furness where, owing
to mistaken identity, the Society failed to obtain convictions.
These were the only two cases in which there was failure to secure
convictions.
Dicksons, Ltd. (Ph. J., March 14). — Proceedings have in two
instances been taken under Section 17 of the Pharmacy Act, 1868.
A limited company trading as seedmen were summoned at the
Chester Police Court for selling arsenical weed killer without com¬
plying with the regulations required to be observed in the sale of
articles in Part I. of the Schedule to the Act. For the defence it
was urged that the defendants only acted as agents for a firm of
chemists, but the magistrates, after due consideration, felt bound
to convict.
Battle, Son, and Maltby (Ph. /., December 19). — At the Lin¬
coln Police Court a firm of chemists were charged with selling
vermin killer containing strychnine through the post and over the
counter to persons who were unknown to them. They were
further charged with not labelling the article with the word
strychnine and with their names and address. The magistrates
convicted on the summonses for selling to unknown persons, but
in the cases of alleged improper labelling the summonses were
dismissed. Leave was given to appeal on the latter point.
Boots, Limited (Ph. J., May 2). — In one instance proceedings
were instituted under the Companies Acts. A limited company,
trading as chemists, was summoned at the Bristol Police Court
for not affixing the word “Limited” after their name, and a
penalty was imposed.
Ingram (Ph. J., April 4). — The fiat of the Attorney-General
having been obtained, a petition for the revocation of a patent for
6
PHARMACEUTICAL JOURNAL.
[Jan. 2, 18W
liver pills came on for hearing in the Court of Chancery. The
particulars of objection to the patent pointed out that all the
individual drugs in the patent were well known, and that they
were continually compounded in different proportions by chemists
and druggists and prescribed by medical men. Formal evidence
in support of this statement having been given, Mr. Justice Romer
revoked the patent and gave the petitioners the cost of the
proceedings.
The fact that the revision of the British Phar-
Praetieal macopceia was known to be definitely in band,
Pharmacy, and the doubt whether any further suggestions
in regard to matters to be included in that work
would receive attention, probably accounted for the comparative
scarcity of communications during the year such as had occupied
practical pharmacists for some time previously. But whilst the
flood of criticism has abated considerably, suggestions for the
modification and possible improvement of galenical preparations
have been as plentiful as ever. That old bone of contention —
Blaud’s Pill — has been found by R. C. Cowley to vary greatly as
regards the amount of ferrous carbonate present in commercial
specimens, and curiously enough many proved to be
stronger than pil. ferri, B.P. A modification of the official
formula devised by W. Lyon was found to yield a pro¬
duct equal to that of the original, whilst the bulk of the mass
wa3 diminished by one-fifth. Further, H. Wyatt showed that by
the use of sodium bicarbonate, as recommended by Dr. Ravil, an
excellent mass can be produced, which contains the maximum
amount of ferrous carbonate, the carbon dioxide evolved during
the reaction apparently protecting that salt. Vinegar has also
received an inordinate share of attention ; Cowley was unable to
purchase from retailers specimens according with the B.P. standard,
but Pearmain and Moor urged that vinegar of B.P. strength is obtain¬
able, and that the pharmacists’ standard should not be lowered
whilst B. S. Proctor objected to the limitation of the term “ vinegar”
to preparations prepared from malt. Some slight skirmishing on
the application of the term “ white wine vinegar ” also served to
lend variety to the fare provided in the Journal pages.
Cachets and Cachet Machines received the attention they
deserve in a special illustrated article devoted to those encroach,
ing novelties in British pharmacy. Solutions official in the
Pharmacopoeia have been commented upon, as well as the Wines
and Syrups, modifications of existing formulae being recommended
wherever found desirable in practice. Cod-liver Oil Emulsions,
in all their varieties, received attention in a comprehensive
summary by Professor Gay, of Montpellier, and P. C. Arblaster also
devoted attention to this topic ; the suitability of spirit, ammon.
aromat., as a massing agent for Pil. Coloc. Co., previously pointed
out by T. Dunlop, was confirmed by W. Lyon ; Mansier referred to
the advantages accompanying the administration of medicaments,
in the form of Medicated Granules ; and J. Cocks, of Plymouth,
published some useful notes on Pill coating, besides devising a
simple form of coating apparatus. British and Foreign
Syrups were treated of in a most exhaustive fashion by
J. Ince ; a good word was put in for Ext. Ipecac. Acet.
and wine made therefrom, by A. Laing ; the use of methylated spirit
to exhaust the root, in preparing Ext. Pareir^e Liq , was recom¬
mended by J. Barclay, who also found that Ext. Coloc. Co. is a
product that varies in more ways than one. Spiritus 2Etheris
Compositus was the subject of a paper by W. I. Clark and D. B.
Dott ; the solution of the sugar in Mist. Ferri Co. with the iron
sulphate, instead of mixing with the myrrh and potassium car¬
bonate, was recommended by W. Johnston, who also pointed out
the possible decomposition of Cocaine in Ointments ; the phar¬
macy of Phosphorus was very completely dealt with by W. Martin -
dale ; and some experience gained in an attempt to prepare a small
quantity of Castor Oii, Soap was communicated by J. F. Brown,
of Dover, who also suggested a modified formula for Miscible
Ext. Cocas Liq.
A formula for Eucalyptus Ointment was sent by J. Bosisto,
of Victoria ; Granular Effervescents were practically
treated in useful papers by W. T. C. Clarke and G. Lunan ; the
Preservation of Chloroform was the subject of a short note
by D. B. Dott; and the preparation of Nutrient Beef Foods was
described in an excellent paper by A. W. Gerrard. Another some¬
what extra-pharmaceutical subject — the Sterilisation of Milk —
was profitably treated by J. A. Forret. Malt Extract and Cream
of Tartar were the subjects of notes by M. Conroy, the latter
being a reply to one by C. A. Hill ; and A. H. Allen also wrote
on the composition and analysis of the same compound. An
article on the making of Compressed Tablets by F. Edel
embodied much useful information, whilst the fillicg of Capsules
was briefly described by E. P. Ferte, and a new and convenient form
of Extraction Apparatus for the extraction of drugs by hot or
cold solvents has been devised by J. H. Hoseason. The comparative
insolubility of Cocaine in vaseline or lard was referred to by C. E
Sage, who showed that neither is a suitable solvent for the base.
The Conference at Liverpool brought forth both good and in¬
different papers as usual, but on the whole a fair average quality
was maintained this year. E. H. Farr and R. Wright recommende
that the green fruit of Conium Maculatum should alone be
retained for official preparations, and that Ext. Conii Liq. should
be official in the next B.P. They have also found that the official
Succi are extremely variable in degree of potency, whilst Wright
pointed out that existing formulas for Liquor Auri et Arsenii
Bromatus yield products differing materially both in strength and
composition. Japanes Fennel and its oil were dealt with by
J. C. Umney, who showed that the latter differs but little from
normal oils distilled from other varieties; he also dealt with
the effects of climate and soil on Peppermint Oils. The separated
siftings of Belladonna Root powder were compared by R. H.
Parker, whose results indicate that the finer powder gives a darker
coloured alcoholic tincture but contains less alkaloid, and that the
removal of this powder to the extent of forty per cent, increases the
alkaloidal potency of the remainder by about thirty per cent.
S. Hardwick spoke on the making of Compressed Tablets at the
dispensing counter, showing that it is quite a simple matter to
prepare and dispense small quantities of tablets; F. C. J. Bird
explained how Formaldehyde may be advantageously employed
in pharmacy as an antiseptic, particularly in the case of infusions ;
C. T. Tyrer communicated a note on Pyroxylin, B.P. ; A. C. Abra¬
ham discussed Indian Bael and its preparations; J. A. Forret
gave a formula for Essence of Rennet, and J. F. Liverseege
described the effects of solvents on the analytical characters of
Ginger. The remaining papers came more within the scope of
chemistry and physics than pharmacy.
More recent communications include a paper on the standardisa¬
tion of Solid Extracts, by C. H. La Wall ; another, in which the
miscibility of different Ointment Bases has been very fully dealt
with by A. St. Onge ; a summary of the requirements in Denti¬
frices of various kinds, by Miss 0. M. Conklin ; P. H. Marsden has
published some useful results bearing on the solubility of the
Double Cyanide of Zinc and Mercury; a note on Sherry
Wine, by E. W. Lucas, some of whose data were called in question
subsequently ; and a useful paper on Uniformity in Pharmacy,
by C. F. Henry. On the whole, then, it will be seen that the past
year has been productive of a fair amount of useful matter bearing
Jan. 2, 1897.]
PHARMACEUTICAL JOURNAL.
7
directly on pharmacy, especially when we consider the numerous
brief and practical notes read before the more active local associa¬
tions, which lack of space will not permit to be even enumerated
here, whilst comments are scarcely called for in those cases.
During the past year valuable additions have
The been made, both to the Museums of the Society
Society’s and to the Herbarium. The following are some
Museum. of the principal donations. More than a hun¬
dred specimens of the medicinal plants of the
Stra'.ts Settlements have been presented by Mr. H. N. Ridley, M.A.,
from the Botanic Gardens at Singapore, in illustration of a work on the
native medicines on which the donor is engaged. The prize herbarium
of British plants for the year 1896 has been presented by Mr. F.
Giles, and has proved a source of considerable interest to visitors
and students. Professor Dr. Schweinfurth has contributed a
valuable set of specimens of the trees yielding myrrh and allied
gum resins and gum Arabic, as well as specimens of
drugs from Egypt and Arabia. Nineteen West African
native medicines have been received from Dr. E. B. Ormerod,
and a valuable series of essential oils from Messrs. Horner
and Sons, together with specimens of the products from which
they were distilled, thus adding considerably to their authenticity.
The Museum of the North British Branch has received during the
year more specimens than it is at present able to display satisfac¬
torily, consisting of the materia medica collection of the Royal
College of Physicians of Edinburgh, including a valuable series of
rare drugs, known as the Martius collection, which originally
belonged to Dr. Th. Martius, of Erlangen. It will also probaby
acquire the collection of the late Dr. Scoresby Jackson. The work
done in connection with the Museum includes a description of a
false jaborandi, consisting of a new species of Swartzia ( S.decipiens ),
the chemical examination by Paul and Cownley of the leaves of
Aracati jaborandi and of P. microphyllus, which seem to indicate that
at least two alkaloids are present in each variety of jaborandi. The
difference between the two commercial varieties of patchouli ( P .
patchouli, Pell. ; P. comosus, Miq., Pli. J. [4], ii., pp. 221-1) has been
pointed out by Messrs. Sawer and Holmes ; the adulteration of
bloodroot with the rhizome of Chamcelirium carolinianum has
been indicated ; the identification of myrrh as the product of
Commiphora abyssinica and C. schimperi has been shown to rest on
inadequate evidence, B. myrrha, Nees, being the only plant to
which the drug can be attributed with, any degree of
certainty ; the source of proteacin has been ascertained to be
Leucadendron decurrens, R. Br. ; the root of Tephrosia macropoda has
been examined by Professor Plugge and found to contain a heart
poison net identical with cytisin, and which is not an alkaloid. A
specimen of papaine forwarded by the Indian Government to the
Museum for examination has been reported on by Mr. J. C. Umney
as of good quality. Series of duplicate specimens of materia medica
have been distributed to the Local Associations at Aberdeen and
Exeter, to the University Colleges at Liverpool and St. Andrews, to
the Royal College of Science at Dublin, and smaller donations to the
New York College of Pharmacy, and to Dr.G. Planchon, of Paris, and
Dr. Tschirch, of Berne ; and some living roots received from abroad
to the Botanic Gardens, at Kew, Edinburgh, Cambridge, and Dublin.
Continued attention has been paid during the
The year to the maintenance of the efficiency of the
Society’s Library in London, both by providing the more
Library. important new books, and in securing the regular
receipt and binding of scientific, as well as
pharmaceut’cal periodicals. The principal new books added are : —
‘The Chemistry of Urine’ and vol. iii., part 3, of ‘Commercial
Organio Ar a’ysi®,’ by A. H. Allen ; new editions of Thorpe’s
‘ Inorganic Chemistry ’ and Bloxam’s * Chemistry, Inorganic and
Organic’; ‘Analysis of Food and Drugs ’and ‘Applied Bacterio¬
logy ’ by Pearmain and Moor ; ‘ Chemical Recipes,’ by the Atlas
Chemical Company; Clowes and Coleman’s ‘ Quantitative Analysis’;
Ramsay’s ‘ Gases of the Atmosphere’; Gattermann’s ‘Practical Methods
of Organic Chemistry ’ ; ‘ Agricultural Analysis,’ by Addyman ;
‘ Elements of Agriculture,’ by Fream ; Van Heurck’s ‘ Treatise on the
Diatomacc re,’ translated by Dr. Wynne E. Baxter, a worthy companion
to the work on ‘ The Microscope ’ ; ‘ Text- Book of Bacteriology,’ by
Crookshank; Van ’t Hoff’s ‘Studies in Chemical Dynamics’;
‘ Chemistry in Daily Life,’ by Lassar-Cohn ; ‘ Dictionary of Chemi¬
cal Solubilities,’ by Comey ; new editions of ‘ Poisons,’ and of
‘Foods ’by Wynter Blyth ; Yeo’s ‘ Food in Health and Disease’;
Caspari’s ‘ Treatise on Pharmacy ’ ; ‘ The Art of Compounding,’ by
Scoville ; Southall’s ‘ Organic Materia Medica,’ 5th ed., by Barclay;
‘ Lectures on Pharmacology,’ vol. i., by Binz ; vol. ii. of Green’s
‘ Manual of Botany ’ ; ‘ Index to Watt’s Dictionary of the Economic
Products of India’; Fiiigel-Schmidt-Tanger’s ‘German and
English Dictionary’; anew edition of Lee’s ‘Microtomist’s Vade-
Mecum’; Cole’s ‘Methods of Microscopical Research’; PriDgle’s
‘ Photo-micrography ’; Cross and Cole’s ‘Modern Microscopy’;
Sutton’s ‘Volumetric Analysis’; ‘ Nueva farmacopea mexicana ’ ;
part 3 of Dammer’s ‘ Chemische Technologie’; ‘ National Formulary,’
revised edition ; Bretschneider’s ‘ Botanicon Sinicum,’ vol. iii. ;
‘Memorials of the Faculty of Physicians and Surgeons of
Glasgow,’ and the first volume of the second series of the great
‘ Index-Catalogue of the Library of the Surgeon-General, U.S.A.’
The three rooms which comprise the London Library have been
rendered brighter by a much-needed repainting and whitewashing.
According to the Librarian’s record, only two small books were
missing from the shelves between the annual stocktakings of 1895
and 1896, while two other volumes, previously reported missing,
were found to have been returned to the shelves. The number of
volumes lent out during the year is about 2000, nearly half having
gone to the provinces. The utility of the Library, cannot, how¬
ever, be fully gauged by the numbers of books lent out, or by
signatures in the attendance book, as the Librarian has frequently
to answer written and veibal applications for information of which
no record is kept. The Librarian has reported that a very successful
meeting of the Library Association was held at Buxton in the first
week of September.
From the Library in Edinburgh about 1400 volumes have been
lent out during the year, of which 164 were to provincial readers.
The Library continues to be made use of largely for purposes of
reference. About 60 volumes have been added during the year,
mostly by purchase, and a few as donations. These include
periodicals, received as published, and standard books, among which
maybe mentioned Allen’s ‘ Chemistry of Urine,’ Cole’s ‘Studies in
Microscopical Science,’ Everett’s ‘Physics,’ Fresenius’ ‘Qualitative
Chemical Analysis,’ Gattermann’s ‘ Practical Organic Chemistry,’
Green’s ‘ Manual of Botany,’ Lassar-Cohn’s ‘ Chemistry in Daily
Life,’ and his ‘ Manual of Organic Chemistry,’ Pearmain and Moor’s
‘ Analysis of Food and Drugs,’ Sutton’s ‘ Volumetric Analysis,’
Tilden’s ‘Chemical Philosophy,’ and Wanklyn’s ‘Water Analysis.’
No annual summary is, unfortunately, com-
Death Eoll plete without the mournful epilogue in which
of the we honour the names of those who, after good
Y ear. and faithful service in pharmacy or in science,
have passed hence. Prominent among thos$
who contr ibuted to the sum of human knowledge in their respective
spheres of activity are Dr. J. Langdon Down and Sir B. W. Richard¬
son, the former a distinguished student of the Society’s School in its
ear ly days, and a valued honorary member of the Society for many
8
rHARMACEUTICAL JOURNAL.
[Jan. 2, 1897
years. Among corresponding members the Society has to deplore
the loss of Dr. Trimen — the co-worker with the late Professor
Bentley in the production of the now classical work * Medicinal
Plants ’ — and Baron Ferdinand yon Mueller, Government Botanist
at Melbourne and an eminent authority on the Australasian Flora.
The list of deaths during the year also includes the names of
T. C. Betty, Marshall Leigh, and G. F. Schacht, the latter of
whom had filled the office of Vice-President of the Society, and all
■ of whom had served the Society as members of the Council. The
• death of the following local and divisional secretaries has likewise
to be recorded : — H. Saxby (Lewes) ; R. H. Swingburn (South
Molton) ; J. W. Littlefield (Ventnor) ; J. B. Parkin (Ripon) ;
F. Codd (Devonport) ; W. B. Stonham (Maidstone) ; F. Baker
(Sandwich) ; T. Howard Hall (East Islington) ; H. A. Thomas
• .(City) ; and W. Gulliver (St. George’s).
PARLIAMENTARY NOTES AND NEWS-
Diplomatic and Consular Reports and communications from
British representatives on matters of commercial or general
interest are now published in a manner which will render them of
some value. The good old bureaucratic idea of pigeon-holing
every report received has given way at last to the more rational
consideration that as these reports were meant to be of value to
the commercial and general community they should be freely
obtained through the ordinary channels. Thus is to be explained
the somewhat startling line “to be purchased either directly or
through any bookseller,” which now appears on official publica¬
tions of this kind. “ The Report on the Petroleum Industry in
Roumania,” which may be purchased for twopence with one’s
morning paper, is a good instance of what the Foreign Office can
do in the way of producing cheap, and possibly beneficial, litera¬
ture.
A Special Commission has been appointed to inquire into the
condition and prospects of the cane sugar-growing islands of the
British West Indies. The Commissioners are three in number,
viz., General Sir H. W. Norman, C.I.E. (Chairman) ; Sir Edward
Grey, Bt., M.P. ; and Sir David Barbour, K.C.S. I. Mr. S. Olivier,
B.A., will accompany the Commissioners in the capacity of Secre¬
tary, and Dr. D. Morris, Assistant-Director of the Royal Gardens,
Kew, is to be the expert of the party to advise on botanical
matters. Sugar-growing was the staple industry of the West
India Islands, and anything affecting the growth of the cane or
interfering with the disposal of the refined product induces some¬
thing approaching a crisis. It should go a long way to remove
anxiety in the minds of colonial planters to know that the Home
Government has promptly recognised the seriousness of existing
conditions, and has promptly taken steps to see what can be done
towards remedying such conditions.
The British West Indies, however, are not the only sufferers.
A consular report on the trade of Martinique and Guadeloupe, just
issued by our Foreign Office, shows that the French Colonial
Department is sorrowing over very deplorable accounts from these
islands. A series of visitations, in the shape of fires, cyclones, pro¬
longed droughts, and disease have ruined the crops and exhausted
local resources. The exports have fallen enormously, and the im¬
ports have also diminished, owing to the difficulty of remitting for
the goods. Measures of relief for the planter are in prospect, and
even now he is encouraged by the remission of the duty on artificial
manures to pay some attention to enriching the soil : 5000 tons of
chemical manure reached the island in 1895 from England. There
is evidence that in default of sugar raising, the planters in both
British and French West Indies will turn their attention to second¬
ary cultures. Coffee, cocoa, cassia, and logwood are already
figuring in the exports. Most of the produce at present goes to
France.
NEW IDEAS.
SOLUBLE ANTISEPTIC PELLETS.
For some time past the Sanitas Company, Limited, has manu¬
factured L.G.B. corrosive sublimate pellets, but they have only
been put up for sale in bottles. The firm has now placed on the
market the same article in small tubes, retailing at 4 d. each, and
containing eight pellets, each of which when dissolved in half-a-
pint of water yields a solution of 1 in 1000. The same firm has
added to its manufactures pellets of potassium permanganate and
carbolic acid pellets, both of which should prove very useful in
numerous instances, on account of their extreme portability.
COMPOUND PHENACETIN TABLOIDS.
The constantly increasing use of phenacetin as an analgesic and
antipyretic has suggested to Messrs. Burroughs, Wellcome and
Co. the preparation of tabloids of the following formula
R. Caffeine, gr. 1 ; phenacetin, gr. 4. It is anticipated that the
combination of phenacetin with so useful a cardiac stimulant as
caffeine Mill prove therapeutically useful in many ways, and already
a number of reports have been received of its excellent effect in
relieving the sick headache of migraine. The tabloids are supplied
in bottles containing twenty-five and one hundred.
NOVEL DISPENSING BALANCE.
An ingenious balance for weighing a number of powders of the
same weight has been devised by Nithack, and is manufactured
and sold by F. Russ, of Vienna. A circular rotating plate with ten
apertures supports as many horn capsules. Below the plate is a
fixed balance, into the pan B of which the weights are placed. The
arm opposite to this pan supports the capsule C, which has been
previously counterbalanced. The powder having been weighed
into the capsule C, the lever A, working backwards and forwards,
lifts the plate and with it the capsule, rotates .t, and brings the
next capsule over and deposits it on the arm of the balance ; the
weighing can thus be repeated with great ease'and rapidity. The
pointer of the balance projects above the plate and, moving over a
graduated scale, allows of an accurate weighing being made.
Jan. 2, 18t7J
PHARMACEUTICAL JOURNAL.
9
PHARMACEUTICAL SOCIETY.
MAJOR EXAMINATION PAPERS.
DECEMBER 29 and 30, 1896.
[Time Allowed for each Paper— Three Hours ]
CHEMISTRY.
[Six questions on7]/ are to be attempted ]
1. One and the same electric current is simultaneously parsed through so’u-
tions of the following substances in successi >n Hydroch'oric acid, sulphuric
acid, sodium sulphate, potassium chloride, ferrous sulphate, ferric sulphate.
What would separate at the cathode and anode respectively in each case ?
Calculate also the weights of the several substances which wou d separate
whilst 5 grms. of hjdrogen were being evolved from the hydrochloric acid
solution.
2. What are the several ways in which argon has been isolated, what are its
distinctive properties, and on what grounds is its molecule believed to consist of
a single atom?
3. Describe the method of obtaining glycerine on an industrial scile. Explain
by means of equations any reactions with which you are acquainted into which
this substance enters, and indicate what light they throw on its constitu' ion.
4. How could the following substances be obtained from benzene : — Toluene,
benzoic acid, salicylic acid, phenol, benzaldehyde, phenylhydrazine, benzyl
chloride ? Indicate also how benzene could be ob tamed from each of these
.5. State what you know about the thermal phenomena attending the neutralisa¬
tion of strong acids by strong bases in dilute solution, and point out what
inferences have been made from the facts.
6. What process or series of processes would you adopt in order to obtain : — -
(a) Sulphur from potassium sulphate,
(b) Phosphorus from potassium phosphate,
(c) Carbon from potassium carbonate,
(d) Nitrogen from ammonium nitrate ?
7. Give an account of the action of atmospheric air on an aqueous solution
containing, originally, ammonium sulphide.
8 What is the composition and constitution of phenylhydrazine What is its
action on : —
(a) Aldehyde, (6) acetone, (c) fructose, (d) glucose?
9. Plow is ammonium sulphocyanide prepared ? Describe the action of heat
upon it.
A Paper.*
PRACTICAL BOTANY AND MATERIA MEDICA.
1. Describe in technical language the flower A. Refer it to its Natural Order,
and give reasons for your determination.
2. Cut sections of specimen B. Mount not more than two in dilute glycerine,
and leave them with explanatory sketches for inspection by the examiners.
Briefly describe the structures shown in your prepaiations, and identify the
specimen as far as you are able.
3. Examine the bark provided, and make a microscopical preparation to dis¬
play any peculiarity of structure which it presents. Leave with your prepara¬
tion a short desc>iption calling attention to such peculiarity.
4. Ascertain the constituents of the powder C.
B Paper. *
BOTANY AND MATERIA MEDICA.
1. Give some account of the mode of formation of the grains of sttrch present
in the cells of the tuber of a potato. What is the ultimate fate of these starch-
grains ?
2 Give an account of the external features of any British Fern. Compare and
contrast the methods of reproduction in a Moss and a Fern.
3 Give an account of the different forms of fruit found among plants
belonging to the natural order Rosacese. In each case you mention say from
what part of the flower the succulent portion of the fruit is derived.
4. Describe the histological features of Cinchona succirubra bark. How is this
bark distinguished from that of other cinchonas? How may the presence of
cinchona alkaloids be readily demonstrated?
5. By what reactions would you recognise the presence of Quinine, Morphine,
and Strychnine ?
SELECTED PRACTICAL FORMULA
The following specially selected formulae are published in the
hope that they may convey some seasonable hints to readers of
the Journal (see also last volume, p. 468) : —
Embrocation for Whooping Cough.
Rectified Oil of Amber .. .. .. 1 ounce.
Oil of Cloves . 1 ounce.
Olive Oil , . . . . . . . . . 3 ounces.
Mix.
PHYSICS.
[Six Questions only are to be attempted.]
1. Describe in detail the way in which the metric measures and weights have
been obtained, at d give approximately their equivalents in the English system.
2. How do the spectra obtained by means of prisms of different kinds of glass
differ from each other and from those produced by gratings ?
3. What do you understand by the interference of 1 ght ?
4. Describe the construction and action of some form of electrometer.
r 5. How is the relative electric conductivity of a solution of a salt affected by
dilution ?
6. How is the pressure of vapour of a liquid determined ? What happens if
the volume of a saturated vapour is diminished ?
7. State the law of Dulong and Petit. What elements are notably exceptional
in regard to this law ?
8. How may an electric current be produced by means of a magnet? Describe
a machine by which a direct continuous current of electricity may be obtained
through the intervention of a magnet.
9. What is the action of heat on iodine, elementary arsenic, arseniaus an¬
hydride, ice, and sulphur? Would any of the phenomena be changed by the
increase or diminution of pressure during the heating ?
A Paper.*
BOTANY AND MATERIA MEDICA.
1 . Give an account of the changes which take place in the contents of the
cells of the endosperm of the barley grain as germination proceeds. Explain
these chemical changes as far as you can.
2. What are the most important characteristics of mosses ? Give an account
of the st mature and life history of any British moss.
3. Compare the Natural Orders Ranunculacese and Rosacese, with regard to
their vegetative and floral organs.
4. De-cribe the histological features of Ipecacuanha. What are its active
principles ? In what proportions are they present ? Mention the source of the
official drug, and give the chaiacters which distinguish it from other varieties.
5. How is Cod-Liver Oil prepared ? Give an account of its chemical com¬
position. How would you distingui h it from other fish oils ?
B Paper.*
PRACTICAL BOTANY AND MATERIA MEDICA.
1. Describe in technical language the flower D. Refer it to its Natural Order,
and give reasons for your determination.
2. Cut sections of specimen E. Mount not more than two in dilute gly erine,
and leave them with explanatory sketches for inspection by the examiners.
Briefly describe the structures shown in your preparations, a . d identify the
specimen as far as you are able.
3. Examine the bark provided, and make a microscopical preparation to display
any peculiarity of structure which it presents. Leave with your preparation a
thort description calling attention to such peculiarity.
4. Ascertain the constituents of the powder F.
* Part of the candidates received the papers A, A, and the remainder had the
papers B, B.
T iolet Tooth Ponder.
PrecipRited Chalk
. . 8 ounces.
Cuttlefish Powder . .
.. 2 „
Powdered Castile Soap . .
.. 2
Powdered Orris Root
.. 4
Ionone .
Anethol
Carmine
Tincture of Orris ...
. .
.. \ ounce.
Rub down the carmine thoroughly with a little of the chalk ; add the rest of
the powders. Dissolve the perfumes in the tincture, and add this to the mixed
powder s. Rub till dry.
Orange Bitters.
Soluble Essence of Orange
Soluble Essence of Lemon
Concentrated Infusion of Cusparia . .
orange Wine . to
2 fluid ounces.
1 fluid ounce.
4 fluid drachms,
10 fluid ounces.
Mix, stir in 3 drachms of finely-powdered pumice stone, and filter bright.
Lip Salve.
Benzoated Lard .. .. .. .. 8 ounces.
Spermaceti .. .. .. .. .. 4 „
White Wax . 2 ,,
Oil of Sweet Almonds . 1 ounce.
Balsam of Peru . . . . . . 1 drachm.
Alkanet Root . . . . . . . . 2 ounces.
* Digest the alkanet root, coarsely powdered, in the benzoated lard and the oil
on a water bath, until a spot of mixture when cold shows a deep rose tint, then
add the Peruvian balsam, strain through flannel, and melt the spermaceti
and wax in the bright liquor, finally perfume with —
Otto . 10 minims.
Oil of Ylang Ylang . 5 ,,
Terpineol . 20 ,,
Toilet and Nursery Ponder.
Boric Acid in Finest Powder . . . . 8 ounces.
Oil of Petitgrain . .. 2 m nims.
Oil of Neroli . ..2 ,,
Od of Bergamot . 2 ,,
Otto . 5 ,,
If desired this may be coloured pink by the addition of 10 grains of carmine.
* Part of the candidates received the papers A, A, and the remainder had the
papers B, B.
t Records of experience with any of rinse formulae, if sent by readers, will be
gladly received.
10
PHARMACEUTICAL JOURNAL.
[Jan 2, 1897.
THE STUDENTS’ PAGE.
INTRODUCTORY.
Under this heading it is proposed to publish from time to time
short articles or notes specially designed to assist in removing from
the path of students working at home such stumbling-blocks as all
must of necessity encounter in their studies. These notes will
deal generally with the subjects included in the pharmaceutical
curriculum, difficult points in chemistry and physics, botany,
materia medica and histology, practical pharmacy and dispensing,
being treated as occasion may arise. Amongst other matters
lists will be published regularly of such plants as may
be found in blossom, with explanatory notes of their
structure when any peculiarity renders this desirable.
It is, of course, difficult to arrange such lists for all parts of the
country, since seasons and districts vary. Thus, the West of
Scotland, in some sheltered parts, is as mild as Devonshire, and
plants may be in flower from Ayrshire to Orkney that will hardly
be seen in blossom anywhere in England at the same date north
of Kent on the eastern coast. An endeavour will be made to meet
this difficulty by describing any wild specimens which may be
sent for the purpose by those who do not find them mentioned in
the lists published. It should be understood that the lists given
will usually be of plants found in the neighbourhood of London,
and it will serve the purpose of those in colder districts if they will
consult the list of the previous month, since the flowers may be two
or three weeks later in the north than in the south of Britain.
Special attention will also be given to points requiring explanation
in the British Pharmacopoeia, whilst communications are invited
from students who experience any difficulties in their work, as similar
difficulties may occur to others and explanations published in
this page will prove useful to numerous readers.
BRITISH WEIGHTS AND MEASURES.
About the middle of the eighteenth century (1758-1760), Mr. Bird
made a standard troy pound and a standard yard for a Weights and
Measures Committee of the House of Commons. In 1824 these
standards were legalised in order that a uniform system might be
made compulsory for the whole realm. The troy pound was
retained as the standard, because, amongst other reasons,
all coinage was regulated by it and all medical prescriptions were
compounded by it under a peculiar sub-division which the College
of Physicians was most anxious to retain. But though the
avoirdupois pound was, in the opinion of the Commissioners, not
fit to be made a standard, it was in such general use that they
considered its weight should be definitely fixed. Accordingly they
divided the troy pound into 5760 grains, and fixed the weight of
the avoirdupois pound at 7000 such grains. Thus the use of two sys¬
tems of weights was permitted, the troy for particular (jewellers’
and apothecaries’) use, the avoirdupois for general use. The former
was sub-divided in two ways, one for jewellers (ounces, penny¬
weights, and grains), the other for apothecaries (ounces, drachms,
scruples, and grains).
Not long after the legalisation of the standards they were lost
(in 1834) in the fire by which the House of Commons was destroyed.
The Committee which was appointed (1838) to restore the standards
did so between 1843 and 1854, but they replaced the troy pound
by the avoirdupois pound. These standards were legalised ; they
are the imperial standards, and are now deposited in the Standards
Department. The standard yard is the distance between the
centres of two gold plugs sunk in a bronze bar, and the standard
pound is a mass of platinum.
Eour “parliamentary” copies of each of these imperial standards
have been made so as to provide against injury or loss. Two of
them are deposited at the Mint, two at the Royal Observatory
(Greenwich), two with the Royal Society/whilst two are immured
in the parliamentary buildings at Westminster. Other copies
have been supplied to numerous towns. Both systems of weights
previously in use were thus retained, but the avoirdupois was made
the standard, whilst the value of the troy ounce was regulated by
that standard.
By the Act of 1878 it is determined that the sixteenth part of
the imperial standard pound shall be an ounce, the, sixteenth part
of such ounce a drachm, and the seven-thousandth part a grain.
Further 480 such grains shall be an ounce troy.
All articles sold by weight must be sold by avoirdupois weight,
with the exception of— (1) Gold, silver, platinum, etc., which may
be sold by the ounce troy or decimal parts thereof.* (2) Drugs,
which when sold by retail may be sold by apothecaries weight.
The latter (apothecaries weight) consists of the ounce (identical
with the troy ounce), the drachm, the scruple and the grain
(identical with both avoirdupois and troy grain).
In this way it has come about that the following are now legal
weights (amongst others) : — •
Pound (avoirdupois) .
equals
7000
grains
Ounce ( ,, ) .
5 5
437-5
5 5
Drachm ( ,, ) . , .
27-3
Ounce (apothecaries) .
5 5
480
5 >
Drachm ( ,, ) .
5 5
60
Scruple ( ,, ) .
5 5
20
5 5
Ounce (troy, identical with apoth. )
55
480
55
Pennyweight (troy) .
5 5
24
55
There is but one legal pound, the avoirdupois pound, containing
7000 grains, but there are two legal ounces and two legal drachms,
viz., the avoirdupois ounce, weighing 437 '5 grains, and the troy
(or apothecaries) ounce, weighing 480 grains ; the avoirdupois
drachm, weighing 27 '3 grains, and the apothecaries drachm,
weighing 60 grains. The avoirdupois drachm is, however, practi¬
cally obsolete.
THE STUDY OF THE B.P.
The study of the British Pharmacopoeia for examination purposes
is usually regarded by students as a stupendous and unnecessary
labour imposed upon them by an exacting Board of Examiners. A
careful inspection of the Minor syllabus shows, however, that the
memory work insisted upon is limited to a knowledge of the pro¬
portion of active constituent in the preparations of a small number
of potent, and in most cases poisonous, drugs. Yet it is no
uncommon thing to find the pharmaceutical student plodding
through the Pharmacopoeia from A to Z, endeavouring to commit
to memory the proportional composition of every preparation con¬
tained in it — a herculean task which no one, and least of all the Board
of Examiners, expects or desires him to attempt. It cannot be too
strongly insisted upon that this committing to memory of the
proportion of such things as cardamoms, coriander, and saffron in
the various preparations into which they enter is both unnecessary
and injurious. It is unnecessary because the Pharmacopoeia is
essentially a standard book of reference, and as such is always at
hand in any actual manufacturing operation ; injurious because
it is burdening the mind with trivial and useless details.
The object, therefore, which each student should clearly set
before himself in ‘ ‘ grinding up ” the Pharmacopoeia is the
acquisition of such knowledge as will make him a skilful
and safe dispenser, and not a parrot-like acquaintance
with various formulae, to acquire which they — like Silas Wegg
— sometimes “drop into poetry.” The student should endeavour
to make as many as possible of the preparations in the Pharma¬
copoeia, and pay particular attention to their general composition
and physical properties, as well as to their solubility and behaviour
towards substances with which they are commonly prescribed.
But no student should neglect to become perfectly familiar with
the proportions of active constituents in the preparations of those
potent drugs mentioned in the Minor syllabus in pharmacy, in the
first place because no one can be a safe dispenser without that
knowledge, and also because he cannot expect to pass the
examination without it.
THE FLOWERS OF JANUARY.
The wild flowers most likely to be found in blossom early in
January are Capsetta bursa-pastoris, Ulex europceus, and Senecio
vulgaris. A naturalised plant, Petasites fragrans, may also be
found in flower in the south of England. In gardens the Helle-
borus niger ( Ranuncidacece ) and Jasminum nudiflorum ( Oleacece, ) are
just coming into blossom, and the greenhouse plants, ' Schizostylis
caccinea ( Iridacmi ), the Roman hyacinth, tulips, and lilies of the
valley ( Liliacece, ), narcissus of various species ( Amaryllidacece. ), and
Acacia of various species ( Leguminosce ), Poinsettia and Euphorbia
jacquinceflora ( Euphorbiacece ), Dendrobium nobile ( Orchidacece ) are
available for examination, being easily obtainable from florists.
In botanical gardens Hamamelis virginica may still be found in
blossom. Explanations of difficult points in connection with
several of these plants will be given next week.
* This is the reason why in sets of troy weights the sub-divisions of the
ounce are decimal parts of an ounce. The pound troy is not a legal
weight.
JAN. 2, 18t7j
k HARM ACE UTICAL JOURNAL.
11
PWABIUCEUTIBAL JOUBHAL.
A Weekly Record of Pharmacy and Allied Sciences
ESTABLISHED 1841.
Circulating in the United Kingdom, France, Germany,
Austria, Italy, Russia, Switzerland, Canada, the
United States, South America, India,
Australasia, South Africa, etc.
Editorial Office: 17, BLOOMSBURY SQUARE, W.C.
Publishing a^d Advertising Office : 5, SEfyLE STREET, W.C.
LONDON: SATURDAY, JANUARY 2, 1897.
GEORGE FREDERICK SCHACHT.
Full of years and honourable distinction in his own
vocation, as well as in other relations, a most distinguished
member of the Pharmaceutical Society has gone to his rest.
The record of George Frederick Schacht covers
the entire history of the Society, and in every phase
of his career he gained affectionate regard from
all with whom he was personally associated, as well as
universal respect from those who knew him less intimately.
That such should have been the case was a natural conse¬
quence of his amiable and chivalrous character, his perfect
honesty of purpose and the strict regard for high principle
which marked every action of our departed friend.
George Frederick Schacht’s early pharmaceutical train¬
ing began some years before the foundation of the Society,
in the Pond Street establishment of Messrs. Savory and
Moore, where he was a pupil of John Savory, one of
the members of the first Council. In 1842 young Schacht
became an Associate of the newly-formed Society, and
when a laboratory for practical instruction in
pharmaceutical chemistry was opened in 1844, George
Frederick Schacht was one of the small group
of students who entered for that course, as well as
the lectures by Pereira, Thomson, Fownes, and Red¬
wood. In taking that step Schacht was, no doubt,
influenced by John Savory, who was President of the
Society when the Council in its annual report drew
especial attention to the “obvious necessity of pupils, at the
expiration of their apprenticeship, devoting some months
to lectures and practical manipulations.” By this means it
was urged that “ the active business operations of their future
lives would be rendered more useful to themselves and
others, by giving to the pharmaceutical chemist such a
professional education and knowledge as would justly entitle
him to the confidence of the public.” Schacht’s subsequent
career as a pharmacist afforded ample proof of the sound¬
ness of the views expressed above. As a student he was
very popular with his comrades, and active in carrying
out the arrangements for meetings where, in turn, they read
papers on some subject of interest. One outcome of the work
done in the laboratory was apaper on “unguentum hydrargyri
nitratis,” which was read at an evening meeting of the Society
in March, 1845. He took prizes in both branches of
chemistry and in practical pharmacy, and before the end of
the session passed the Major examination. His removal to
Clifton took place shortly afterwards, and towards the end of
the year a letter from him appeared in the Journal dated
from 3, Regent Place, Clifton.
For some years afterwards he was a frequent contributor of
papers and notes on pharmaceutical subjects to the Journal
and at the meetings of the Bristol Pharmaceutical Associa¬
tion, in which he always took especial interest, and
perhaps the last letter he wrote was to Mr B. Keen,
relating to the business of that Association. As a
pioneer of pharmaceutical advancement Schacht will long
be remembered as having originated the idea which led to
the foundation of the British Pharmaceutical Conference, for
his advocacy of provision being made for provincial education
and of a compulsory curriculum. On a recent occasion
when a very complimentary address was presented to
him by his colleagues in Bristol, he referred to these efforts
with a feeling of regret that he had not met with more
support, but it may safely be predicted that these projects
will yet bear good fruit in the future and long preserve
the memory of their proposer as a man who strove to
fulfil the duty of repaying to his calling the repute which he
derived from it.
One wdio was one of his most intimate friends says of
him : “ I knew Schacht first in 1864 at the Bath meeting of
the Conference, our acquaintance quickly ripening into friend¬
ship, and we have been intimate friends ever since. He
with Giles and Stoddart formed a trio of which we West
of England pharmacists were justly proud. Schacht was
always particularly happy in bringing members of the craft
together and furthering in every way he could the interests
of our body, especially in the direction of advanced educa¬
tion, and his local influence was considerable.
“ I have vivid recollections of his ever hearty cry of
welcome and the genial and kindly hospitality of himself
and of the lady, his wife, who always so warmly seconded
him. In the early days we had many a long tramp together
in the lovely scenery round our respective cities of Bristol
and Bath. I first taught him to throw a fly, and he became
an enthusiastic fisherman. For many years we never missed
the spring fishing either on Exmoor or Dartmoor, but
latterly the ‘ Wylye,’ near Salisbury, made a more conve¬
nient meeting ground, and only this year he was as keen as
ever, though perceptibly not able to stand so well the fatigue
of a long day.
“ What always impressed me in his character was his
undoubted high principle, which he pushed sometimes
almost to the verge of Quixotism, and his rare magnanimity.
Although a keen and intelligent critic of men and things,
and quick to resent injustice ; sometimes a little too im¬
patient of mere opposition, I never knew him harbour an
unkind thought of anyone, and his loyalty towards those
who were doing good work was conspicuous. A brighter
and more delightful companion it would be hard to find, and
his spirits and pluck to the last were those of a bright
schoolboy.”
Mr. Schacht’s official connection with the Society was of
long duration. From 1863 to 1869 he was a member of the
Board of Examiners. At the opening of the School of
Pharmacy in 1870 he delivered the inaugural address. From
1872 to 1896 he was a member of the Council. From 1879
to 1882 he filled the office of Vice-President. He was
12
PHARMACEUTICAL journal.
[Jan. 2, 18t?T
President of the British Pharmaceutical Conference in 1878
and 1879, having also been Treasurer from 1870 to 1877,
and at the time of his death was Treasurer of the
University College, Bristol, an institution in connection
with which he had been long actively engaged, and had
gained the high esteem of his fellow-townsmen.
The funeral was held on Wednesday afternoon, when the
interment took place in the churchyard at Portbury, a village
six miles from Clifton. In addition to members of the
bereaved family, the ceremony was attended by Mr. Walter
Hilis, President of the Pharmaceutical Society, Mr. Michael
Carteighe, Mr. Charles Ekin, Mr. R. W. Giles, and Mr.
A. L. Savory, who came to pay the last token of respect to
their old comrade and friend. Professor Lloyd M organ, Prin¬
cipal, and Mr. Jas. Rafter, Secretary, of University College,
Bristol, attended on behalf of the institution in whose success
the deceased pharmacist had been so deeply interested, whilst
the Bristol Pharmaceutical Association was represented by
its President, Mr. B. Allen ; the Treasurer, Mr. J. Stroud ;
and the Honorary Secretary, Mr. B. Keen. The mourners
also included Messrs. C. Townsend, J.P., J. W. White, W.
Pitman, G. W. Isaac, T. Burton, and J. T. Long. Thus
was laid to rest a leader in pharmacy, an enthusiast in
matters educational and one who, as a man, gained during a
long and honourable career the friendship and esteem of all
with whom he came in personal contact.
THE ‘ PHARMACEUTICAL JOURNAL ’ AND
CHANGED IDEALS.
The position which pharmacists in all civilised countries
have been accustomed to regard as an ideal one is that of an
individual in whom is vested the sole right to dispense
prescriptions and vend- medicaments, who at the same
time experiences no need to go outside those limits to secure
a sufficient income to exist comfortably and maintain his
professional status with proper dignity. Regarded in the
abstract, such a position appears at first glance extremely
attractive to the dealer in miscellaneous oddments, who
rarely sees a prescription from one year’s end to another.
At the same time, could it be realised, it would
more probably than not prove appalling in its monotony.
But it is never likely to be realised in the future, any more
than it has been realised in the past, for even the recognised
leaders of the craft — both in and out of London — have always
in great measure depended, and will continue to depend, upon
the manufacture and sale of proprietary preparations, the
supply of medicines to medical practitioners who do their
own dispensing, the sale of lozenges, perfumes, sponges, and
the thousand and one articles usually associated in the public
mind with the “ chemist’s shop.” If anyone can point to a
single instance, past or present, of a British pharmacist who has
practised or now practises “ pharmacy pure and simple,” the
case will be both interesting and worthy of special record for
the benefit of future historians.
As was shown in these columns last week, however,
indications are not lacking of the manner in which the
extremely multifarious nature of the modern pharmacist’s
acquirements — which he finds necessary in his constant inter¬
course with a public of an enquiring disposition — is likely to re¬
sult in his ultimate benefit. For the opportunity is offered him
of acting as general scientific adviser to the large number of
persons who resort to him for information, and in the prac¬
tical applications of all the natural sciences a sufficiently
wide field is opened for unlimited enterprise and accompany¬
ing profit. The new ideal too — which impels the
pharmacbt to fit himself to impart information, based on,
practical knowledge, concerning all matters connected with
the varied applications of chemistry, electricity, optics, etc. —
is if anything loftier than the old one, and is certainly far
in advance of the conditions that have actually prevailed.
Moreover the manner in which his ordinary business is
perforce conducted gives him an advantage over others who-
act as scientific experts, as he is daily brought in contact
with his clients in an informal sort of way, and will
frequently be consulted off-hand when a formal meeting
by appointment would be carefully avoide'd. Most phar¬
macists have had personal experience of this fact in a more or
less limited degree, and the object, at present in view is to
induce them to cultivate this branch of their business with
assiduity, continually maintaining their stock of information
on scientific matters at the highest pitch, so that they may
at any moment be able to prove their ability to cope with
technical difficulties of the most varied nature.
The position of the Journal in this matter is to serve as
a ready means of diffusing the latest information on all
matters of interest, and also as a medium of inter¬
communication between those of its readers who
require or wish to impart information. In years
past both these objects have been served in accordance with
the demands of its readers and proprietors, as expressed through
theirelected representatives for the time being. To-day the same
is the case, and in the future this condition of affairs must
of necessity continue. But the changed aspect of pharma¬
ceutical affairs during recent years, or perhaps wre ought to
say the gradual realisation by pharmacists of what the
changing conditions of business necessitate, has resulted in a
very radical alteration in the manner in which the Journal is
conducted. Desires for modifications and additions had
long been freely expressed by individuals from time to
time, at annual meetings of the Pharmaceutical Society
and on other occasions, as well as privately, but no
definite change was possible or indeed desirable until those
to whom had been entrusted the direct care of the Society’s
interests had become impressed with the universality of the
wish lor alterations in the Journal.
The decision now being acted upon has been arrived at
after careful deliberation, and it has met with general
approval. There is no doubt whatever that, at present, the
vast majority of our readers are anxious that “their” Journal
should develop in a certain definite direction, and at the
close of the first complete year during which the new lines
have been followed, it is gratifying in the extreme to find
with what unanimity the progressive tendency of the respon¬
sible authorities, as interpreted by the Journal, has been
approved. Much more yet remains to be done no doubt,
but if those who ar-e of this opinion will but take the trouble
to inform and educate their elected representatives accord¬
ingly, there can be but one result. Meanwhile, at the
beginning of a new year, a fairer prospect than ever discloses
itself of ways in which the craft may be assisted through the
medium of the Journal, and if the efforts made be but sup¬
ported by those on whose behalf they are made, there is
every indication that both the Journal and its readers will
have gone far towards realising their present and newer
ideals before the close of another twelve months.
Jan. 2, 1897J
PHARMACEUTICAL JOURNAL.
13
ANNOTATIONS.
The British Pharmaceutical Conference is to be held at Glas¬
gow on August 9 next and following days, and already the local
committee appointed to make the necessary arrangements is busil y
engaged in its self-appointed task. The honorary secretary, Mr.
■J. Anderson Russell, has forwarded an advance copy of a circular
which is about to be issued. In this those connected with pharmacy
in the district are asked for contributions to a fund that is beino-
o
raised, to meet the expenses expected to be incurred in carrying out
the arrangements. Apparently it is intended to entertain the
visitors right royally, for it is estimated that a sum approaching
two hundred and fifty pounds will be required for the purpose.
A Spirit of Emulation, coupled with a desire to maintain the
reputation for hospitality gained by Glasgow twenty-one years
Ago, is doubtless influencing our friends in the other “ second city
•of the Empire ” in this matter, and so long as it is clearly under¬
stood that such an expenditure is exceptional and not expected to
be repeated by less wealthy centres, no one need object to the
lavish scale on which the entertainments are proposed to be
planned. But the good of the Conference is the main object to be
aimed at, and it would be a pity to risk a paucity of invitations in
the future by allowing it to be thought that to tender such may
prove a too expensive luxury. It was agreed at the Edinburgh
meeting that such an idea should be rigidly discountenanced, and
whilst thanking Glasgow for its generous sentiments and heartily
thanking its citizens for their gracious hospitality, it will be
necessary to avoid prejudice to other places that may be glad to
•entertain the Conference on a humbler scale.
The Chairman of the Local Committee is Mr. Robert
M'Adam ; the Vice-Chairman, Mr. William L. Currie ; and the
Treasurer, Mr. John Walker, whilst the General Committee, as
apart from the Executive, is a highly representative one, including
residents in some twenty different towns. As might be expected
the list of names differs greatly from that of the 1876 Committee,
though some few of the old names appear again. Change is mani¬
fested in other directions also, for it will be remembered that the
President of the last Glasgow Conference was the late Professor
Redwood, whilst G. F. Schacht, who has so recently passed away,
was Treasurer on that occasion. As mentioned elsewhere in this
issue, Mr. Schacht was the originator of the idea which led to the
first Conference being held.
The Proprietary Articles Trade Association has the sym¬
pathy of Oxford pharmacists, thirteen new members having been
enrolled at a meeting held in the University city on Wednesday,
December 19, whilst several others were previously connected with
the movement to restrain the insane competition in prices. Mr.
Sheriff Claridge Druce, M.A., acted as Chairman at this meeting,
and, on the motion of Mr. Henry Matthews, it was resolved ‘ 1 That
the chemists of Oxford desire to express approval of the objects of
the Proprietary Articles Trade Association, and pledge themselves to
support it in every way ; they also strongly urge upon all proprietors
the advisability of adding their preparations to the protected list.”
The Disapproval of the Glasgow Association (see last
volume, p. 518) has not dismayed Mr. Glyn-Jones, who refuses
to accept the recent vote as the decision of the Glasgow chemists,
and confesses to having been disrespectful enough, on first
noticing the hour at which the vote of the Glasgow and W est of
Scotland Pharmaceutical Association was taken, to attribute the
result to the fact that local supporters of the P.A.T.A. — “who
everywhere are eminently respectable citizens, and dutiful hus
bands and sons ” — were at that hour well on their way to bed.
Becoming serious again, he expresses the opinion that a sur¬
prising amount of misconception apparently existed in the
minds of some of the prominent speakers, and suggests that it
would have been well had the P.A.T.A. been offered
the opportunity of being officially represented. This suggestion
seems only fair and reasonable, whilst the reference to possible
misconception existing in certain minds fully accords with an
opinion we have long held in this matter. Mr. Glyn-Jones has
therefore been asked to write for the Journal a concise account of
the aims and objects of the Proprietary Articles Trade Association,
making the most of its claims to the support of chemists and drug¬
gists, and showing both what has been accomplished and what yet
remains to be done. This article he has promised for an early
date, and if the matter is then properly put before our readers no
further cause of misconception on their part should be possible.
Professor Emil Du Bois-Reymond died on Saturday morning
last, and the University of Berlin is thus deprived of one who was
foremost in the sphere of organic chemistry and physiology. He
was of French-Swiss extraction, and studied in the first place at a
French gymnasium. Proceeding later to Berlin, however, he
became connected with many important investigations, and,
amongst other matters, did much to prove that biological phe¬
nomena are governed by physical and chemical laws. He was
seventy-eight years old at the time of his death, having been
Professor at Berlin University for more than forty years.
The Arsenical Soar Crusade still proceeds apace, Mr. Alfred
Higgs, J.P. , of Kingston-on-Thames, having been fined ten
shillings and costs on December 23, for selling an article — Dr.
King’s Arsenical Soap — found by Dr. Stevenson to contain no
arsenic. The magistrates decided that arsenical soap is a drug
within the meaning of the Sale of Food and Drugs Act, and also
held that the use of the term “arsenical” in an invoice and on a
label does not constitute a warranty on the part of the manufac¬
turers. The Richmond case was again adjourned on Thursday.
Holyrood Table Water. — Water as a beverage owes its agree¬
able taste to the presence of certain saline constituents, among
which alkaline and earthy sulphates, carbonates, and chlorides are
the most important. With a pure water and a judicious selection
of these salts the possibility of supplying table water of excellent
quality need not involve the cost of transport of several hundred
miles from a Continental source. Acting- upon this principle,
Messrs. Macfarlan, of Edinburgh, are introducing an economical
table water, which in all essential characters bears comparison
with any of those imported from abroad. Holyrood water is quite
free from organic impurity, is well aerated, very agreeable to the
palate, and free from the objection often made to mineral water,
that when mixed with wine or spirits it spoils their flavour.
The Benevolent Fund has benefited as a result of the special
appeal to the extent of £44 15s. 6 d., received in subscriptions up
to the end of December, that is to say, nearly forty pounds has
been received during the last week of the year. This is in addi¬
tion to the donation of twenty pounds mentioned last week, which
must be invested, and is therefore not available for pressing
necessities. The letter of Mr. R. H. Parker shows how the Fund
may be readily increased, without disturbing the flow of ordinary
subscriptions, and to all divisional and local secretaries — indeed,
to all members and . associates of the Society— we commend the
practical study of the precept, “ Go thou and do likewise.”
14
PHARMACEUTICAL JOURNAL.
[Jan. 2, 18b7
Progress in Science in 1896.
Nothing of primary importance in chemistry
Chemistry. has been discovered during the pa^t year but, as
usual, the number of minor problems that have
been solved is beyond calculation. Amongst other matters of
interest to pharmacists, the constituents of Aristolochia Aegen-
tina were investigated by Dr. 0. Hesse, who also showed that the
so called Scopolamine Hydkochloeide consists in reality of
salts of hyoscine and atroscine ; Professor Schmidt, however, failed
to find the last two bases in Scopola Root. Professor Fischer
explained the failures experienced in attempts made to convert
Uetc Acid into Xanthine, and Fischer and Ach succeeded in ob¬
taining 7-dimethyl uric acid from which Caffeine can be prepared*
The detection and determination of Aconitine engaged the atten¬
tion of Dunstan, Carr, and Tickle ; J. 0. Umney has carried out a
considerable amount of work on the chemistry of Essential Oils,
and A. H. Allen concluded his summary of the properties of the
Alkaloids of the Veeateums.
The constituents of Rose Oil have continued to interest several
workers, and Erdmann and Huth suggested the retention of the
term Rhodinol for the alcohol from that and other sources. D.
Rainy Brown recommended the adoption of an official method for
the preparation of pure Azolitmin ; George Coull usefully
explained tbe importance and value of Flame Tests ; Professor
Dewar has continued his work on the Liquefaction of Gases ;
T, W. Schaefer has prepared numerous compounds by the union of
Camphob with different Phenols; and Paul and Cownley
have published further results of investigations of Beaziltan and
Columbian Ipecacuanha. R. C. Cowley has found barium
present in a sampleof Hydeobkomic Acid ; H. Kiliihi has advanced
our knowledge of the Digitalis Glucosides and their products
another step. Peoteacin has been further investigated by Merck
and Hesse, who prefer for it the name Leucodein, 'and E. M.
Holmes has advanced the opinion that the botanical source of
the substance is Leucadendron decurrens,'R. Br., and not L. concinnum.
The detection of C'oppee in Vegetable Substance was
the subject of a note by Paul and Cownley, to some extent
confirming the view of Vediodi, that there is sometimes more
copper naturally present in vegetable substances than is found
in those to which it has been added to preserve their
natural colour. The same workers have instituted an examination
of the alkaloids of Jaboeandi ; Dr. Hesse described Rumicin,
Nepalin, and Nepodin, extracted by him from Hum ex nepalensis,
Wall. ; A. Petit and P. Terrat confirmed the opinion that Tea
should be moistened with water prior to extraction with chloroform,
and that dilute alcohol acts better as a solvent of the caffeine in
tea than nearly anhydrous alcohol ; C. T. Tyrer published notes on
Concenteated Hydeobeomic Acid, Hypophosphoeus Acid and
Pyeoxylin. Naylor and Littlefield have examined Cascaeillin
and compared the work of Duval and Alesrandri on substances
known under that name. Cellulose and its derivatives served
Cross, Bevan, and Beadle as the subject cf an excellent paper, in
which their properties were described ; M. Kubli, and, later,
D. Howard have dealt with the testing of Quinine and its salts
Alex. Gunn has written on the determination of total alkaloids in
Coca Leaves; Dr. Wyrouboff throws doubt upcn the universality
of the Pekiodic Law ; and G. Meiling explains the synthetic pro¬
duction of Eucaine. Schimmel and Co. have published additional
useful notes on the testing of Essential Oils ; the present position
of Beeswax Analysis has been summarised by R. G. Guyer ; a
simple methcd for obtaining a Low Tempekatuee is described by
0. E. Sage ; and Professor J. N. Collie has ably described how
Aegon and Helium were discovered.
The explosive properties of Acetylene have been studied during
the year, and two accidents have been caused in connection with that
gas; Calcium Carbide has naturally assumed a position of consider¬
able importance as a commercial product; Compressed Gases gener¬
ally have been referred to in detail by T. Maben ; and multitudinous
other items of more or less indirect pharmaceutical interest have
been published in these columns during the twelve months that
have just elapsed, and the closing days of which have been so
notably marked by the opening of the Davy Faraday Research
Laboratory, the magnificent gift of Dr. Ludwig Mond to his
adopted country.
The most striking advance in the domain of
Physics physics and photography during the past twelve
and months has been the discovery of the “ X ” rays.
Photography, by Professor Rontgen. That this discovery lies
rather in tbe domain of physics than photography
cannot be denied, the latter being, as it were, dragged into it by
the use of the sensitive dry plate. Notwithstanding the very large
number of experiments which have been conducted by various
workers since Rontgen’s first announcement, it may be said
that we know but little more of these rays than he told us.
Of their application to surgery it is hardly necessary to speak
except to point out their ever increasing use in this raspect. As
to the nature of the “X” rays practically nothing is known.
The assumption that they are light waves of extremely short wave
length hardly seems tenable, for shadows produced by wave trans¬
missions are never absoluiely sharp, the wave movement being
propagated within the geometrical shadow in increasingly less
quantity as the wave lengths become shorter. This, of course, is
well known, for in the case of sound waves — their lengths being-
of feet and inches — the shadow penetration is excessive, and with
light — where the wave lengths are measured in microns or
thousandths of an inch— this shadow penetration can only he de¬
tected readily by special instruments. Then agaiD, the phenomena
of interference and refraction are characteristic of wave motion, and
yet the “ X ” rays cannot be either refracted or give rise to inter¬
ference. If the vibration of the waves are transverse they may be
polarised, and as at present we know of no light which cannot be
polarised, and the “X” rays cannot be polarised, it seems but
reasonable to conclude that the “ X ” rays are not transverse but longi¬
tudinal vibrations, and not light rays. On the other hand, it should
be pointed out that the “X” rays produce the effects of ultra-violet
light in producing dermatitis, in discharging electrically charged
conductors, and in increasing the conducting power of selenium.
Whilst considering the “X” rays and their connection with wave
motion, one cannot help being irresistibly reminded of two
striking facts which have keen brought prominently forward
recently — the one the possibility of telegraphing without
wires, as suggested by Preece ; and the other, what has
been termed the electric eye brought forward by Professor
Bose, of Calcutta. Consideration of these two subjects shows
that, after all, what is being done here is the utilisation of the Hert¬
zian electric waves. Preece was led to his subject by hearing the
conversation going on between two users of the telephone, though
his wire was not connected with theirs. It seems probable that
here he had actually been listening to the effect of a current in¬
duced in his wire from the neighbouring wires, a well-known phe¬
nomenon, which, of course, is taken advantage of in electro¬
magnets and coils of all kinds, whether medical or the more
powerful Ruhmkorff. In the ’ater experiments, in which Preece has
JAX. 2, 1897]
PHARMACEUTICAL JOURNAL.
15
attempted to telegraph, unsuccessfully at present, from the shore
to a lightship, it is probably not rash to hazard the suggestion that
he has been using Hertzian waves. To some extent the lay, in contra
distinction to the technical, pressis at a disadvantage when, in search
of the wonderful and thrilling, statements are made which are little
short of the absurd, and it is therefore as well to look back to Hertz’s
work to see what he did. It would be out of place here to enter
at any length into Hertz’s work, but by producing an extremely
rapid oscillation by means of an electric current, such oscillation
being probably smaller than the thousandth-millionth of a second,
Hertz proved that it was possible to provoke electro -dy manic waves
in air, to reflect, refract, and condense them, and that they would
also give rise to interference. This being the case, it is but
following the matter to a logical conclusion to test whether they
could not, like the ether vibrations of light, be condensed and
sent to a distance, which is practically what Professor Bose has
-done.
Turning now to matters photographic, we find but little startling
-to record. Thanks to the Jena glass and to the valuable mathe¬
matical calculations of Dr. Rudolph, a new form of convertible
anastigmat lens has been produced, each combination of which
as in itself astigmatically and chromatically corrected, both for
•oblique and central pencils. In England only two lenses which are
novel have appeared, and one of these must, from an optical point
•of view, be considered as a retrograde step, as it is not achromatic
nor corrected for astigmatism and spherical aberration, but as it
.gives that peculiar soft diffusion of focus which is so much
.admired by some schools in photography, it may be also con¬
sidered an advance. The other lens, which is called the stigmatic,
calculated by Mr. Hugh Aldis, of Cambridge, may be said to be
a portrait lens working at F/4, following somewhat on the lines
•of the older Petzval form, since it has a cemented convex front com¬
bination and a back combination composed of two lenses separated
The essentially novel point is in the use of flint glasses of lower indices
of refraction than the crown, which, by the bye, it may be stated
•would, prior to the introduction of the Jena glass, have been an
impossibility. Acetylene has not only claimed a very large amount of
attention from photographers but also a victim or two. Various
dorms of generators have been placed on the market, all, so far as a
comparatively short acquaintance with them will warrant one in say-
og, safe in use. The great value of the light is undoubtedly in its
actinic properties, for if the ordinary three-wick lamp be regarded
as unity and the limelight as 7, acetylene may be placed as 5. This
is somewhat curious, for so far as has been tested at present acety¬
lene seems extremely poor in ultra-violet rays. Ranking next in public
estimation to the “ X ” rays are, undoubtedly, “ animated ” photo¬
graphs. In this case, again, is seen the evolution of an idea which
s by no means new, and it is evident that we have not yet reached
.finality by any means, as improvements are continually being
made.
Photography in natural colours remains practically where it was,
-though increased attention has been paid to it both in its
application to the printing press and to the optical lantern for projec¬
tion. What few novelties there are to record in this direction may
certainly be said to be but slight, and in some cases doubtful
improvements on older and well-known methods of work.
Possibly one of the mo3t striking applications of photography,
about which a great deal more will be heard in the near
-future, is the production of a magazine entirely by photography,
.without the intervention of type or the printing press. Mr. Friese
Greene, the inventor of this process, uses a band or continuous roll
•of paper,, coated on both sides with a gelatino-bromide emulsion,
•and this is exposed to the light of electric incandescent lamps which
are placed inside a glass cylinder, on the circumference of which
are placed the negatives on flexible or celluloid films. If type
matter is to surround the illustrations, the type takes the form oE
stencils cut in opaque or non-actinic paper. After passing over one
cylinder, by which one side is exposed, it passes under another, by
which the other side is printed, and thence into the necessary
developing, fixing, and washing troughs. The action is perfectly
continuous, and an edition of several thousands can thus be printed
off, and it is stated, at considerably less cost than by the
ordinary type and printing processes. The beauty of this
method will be revealed of course in the exquisite reproduction of
negatives.
The one branch of photography which has not only been ex¬
tremely active, but in which it may safely be said there has been
a distinct advance, is in the making of half-tone or process
blocks. Great as have been the strides during the last ten years in
this department, it is only within the past twelve or eighteen
months that investigations have been made into the action and
theory of the cross-lined screen through which such pictures are
taken, and the result is that, whereas but two years ago the
practical process worker knew little or nothing of the why and
wherefore, and obtained his results by rule of thumb and trial and
error, he now has clearly defined mathematical rules and equations,
which enable him to tell, before he begins, what with careful
manipulation he may obtain.
Beginning with the text-books issued during
Botany. the current year, in our own tongue have been
published Bergen’s ‘ Elements,’ the second
volume of Dr. Reynolds Green’s ‘ Manual,’ Macbride’s ‘ Lessons in
Elementary Botany,’ and Dr. Vines’ ‘ Student’s Text-book.’ In
German, Prantl’s ‘ Lehrbuch ’ has attained its 10th edition, under
Dr. Ferdinand Pax’s care, Max. Rees has his ‘ Lehrbuch ’
published at Stuttgart, Landsberg’s ‘ Botanik,’ Baenitz’s ‘ Grund-
ziige,’ the 5th issue of Hansen’s ‘ Repetitorium,’ the third edition
of Willkomm’s ‘ Bilderatlas des Pflanzenreiches ’ is brought to a
conclusion, and lastly Loew’s ‘ Pflanzenkunde.’ A large book in
two substantial volumes is Constantin’s ‘ Le Monde des Plantes,’
and Kerner von Marilaun’s popular ‘ Pflanzenleben ’ has reached
its second edition. Of a somewhat different type are Frank’s
‘Lehrbuch der Pflanzenphysiologie,’ ed. II., and Schindler’s ‘Die
Lehre vom Pflanzenbau auf physiologischen Grundlage,’ so far as
the introductory and general part (Allgemeine Theil).
In the life-history of plants the striking observations of Prof.
J. B. Farmer and Mr. J. LI. Williams on the fertilisation of Fucus,
of which the abstract as yet only has appeared in the Proceedings
of the Royal Society , cannot be passed over in silence. These
authors have succeeded in tracing the actual fertilisation of the
archegonia by the antherozoid, and the subsequent segmentation
process. Thuret and others had recorded the earlier and later
stages, but the actual contact had not been previously observed ;
it is rapidly effected, about ten minutes sufficing from the time
when the antherozoids were placed in the water containing the
female plants. The third volume of the collected papers of Prings-
heim has appeared, under the pious care of his children, and Prof.
F. O. Bower has within the last few days produced the second
portion of his ‘Studies in the Morphology of Spore-Producing
Members,’ it being devoted to the Ophioglossacece, with nine quarto
plates. This is published independently by the author ; the
former parb came out in the Philosophical Transactions.
The important ‘ Naturliche Pflanzenfamilien,’ which is known as
Engler and Prantl’s, continues to progress, several “ Lieferungen”
having made their appearance. Dr. Mez, who had previously mor o-
graphed the Brazilian species of Bromeliacese, has prepared a com-
16
PHARMACEUTICAL JOURNAL.
[J AN
plete account of the order in De Candolle’s ‘ Monographic,’ forming
a thick volume in that series. Professor Radlkofer, of Munich, is
still energetically working at the Sapindace®, and his monograph
of the genus Paullinia, in 316 folio pages, attests his undiminished
appetite for work. A monograph on a different plane is Dr.
Wettstein’s elaborate account of the genus Euphrasia.
On the very day these lines are written has been delivered what
purports to be part of the final volume of Saccardo’s * Sylloge Fun-
gorum,’ it being a general index to the whole of the preceding
eleven volumes, compiled by P. Sydow. A popular issue of Sir John
Lubbock’s book on seedlings has appeared, with a selection from
the figures which adorn the original form.
The consideration of local floras may be fitly preceded by the
mention of two important books, the first, Engler and Drude’s ‘ Die
Vegetation der Erde,’ and the second Warming’s ‘Lehrbuch der
Okologischen Pflanzengeographie,’ in which the plants are treated
according to their environment ; it marks a new stage in the treat¬
ment of this question.
Tourist’s floras for Switzerland are well supplied this year. We
have Mr. Alfred Bennett’s volumes, * The Flora of the Alps,’ with
coloured illustrations, which are, however, out of date, and have
served for another work previously. The popular Gremli’s
* Excursionsflora ’ has reached its eighth edition, and Schroter’s
* Taschenflora des Alpenwanderers ’ its fifth. A work on the trees
of Switzerland has been begun as * Baum- Album der Schweiz.’
Turning to our own country, we find new editions of Mrs.
Lancaster’s * British Ferns ’ and ‘ Wild Flowers Worth Notice,’ Mr.
Step’s ‘Wayside and Woodland Blossoms ’ in a second issue, and a
small volume by the Rev. George Henslow, ‘ How to Study Wild
Flowers.’ The excellent ‘ Students’ Handbook of British Mosses,’ by
Messrs. Dixon and Jameson, will be welcomed by working crypto-
gamists. Of new county floras there are two, of Ayrshire and of
Dumfriesshire, the latter by Mr. G. F. S. Elliot, and noteworthy by
its recording the names of the insect visitors to the various species.
Again crossing the Channel, we find a ‘ Flore des Algues de
Belgique,’ by E. de Wildman, and for France two series of ‘ Nouvel
Atlas de Poche des Plantes,’ with coloured figures, by W. Sielain,
the third volume of Rouy and Foucaud’s ‘ Flore de France,’ and the
second of Burnat’s ‘ Flore des Alpes Maritimes,’ which runs from
Tilia to Fragaria but has not yet embraced Rosa. There is also
a flora for the mosses and hepatics of France by M. Douin.
Germany, as might he expected, furnishes many books to the
list, including the continuation of Reichenbach’s ‘ leones Florae
Germanic®, ’ by F. G. Kohl ; Schmidt’s * Pflanzen der Heimath ’ ;
W unisch’s * Die Verbreitesten Pflanzen Nord-Deutschlands,’ and
a companion volume on the fungi. Kohl’s ‘Excursionsflora
Mitteldeutschlands,’ the cryptogams and phanerogams separate,
the 10th edition of Lackowitz’s Brandenburg Flora, including
Berlin ; Kraepelin’s North and Central Germany Excursion
Flora, and last bub nob least, the first parb of Dr. Ascherson’s
‘ Mitteleuropaische Flora,’ which, as might be guessed, is most
carefully done, but by some regarded as almost needlessly
complex. Dr. Drude has brought out the first volume of his
‘ Deutschland’s Pflanzengeographie.’ As regards Austrian local
works, there are Kerner von Marilaun’s ‘Sched®,’ the seventh part,
and a flora of Stiermark, by Krasan, a small pocket volume.
Dr. Engler has brought his ‘ Pflanzen der Osb- Africa ’ to a close,
and Mr. H. Bolus has issued his ‘ leones Orchidearum,’ with fifty
plates, partly coloured. The most important venture in African
botany is the resumption of the ‘ Cape Flora,’ which was begun
more than thirty years ago by Harvey and Sonder, who issued
three volumes. Recently two parts of the sixth volume have been
iesued under the care of the Director of the Royal Gardens, Kew,
comprising ‘Iridace®,’ * Amarylliuace®,’ and ‘Liliace®, ’ the work
of Mr. J. G. Baker.
Messrs. N. L. Britton and A. Brown have brought out the first
volume of an ‘ Illustrated Flora of N. America, Canada, and the
British Possessions,’ with cuts bearing a close resemblance to those
prepared by W. H. Fitch for Mr. Bentham’s ‘ British Flora ’ ; two
more volumes are to complete the work. Another of Professor
Sargent’s splendid volumes on the North American * Silva ’ has
made its appearance, being the ninth, and containing the Cupuli-
fer® and Salicace®. Mr. Trealease has published on ‘ The
Juglande® of the United States,’ with twenty-five plates ; Mr.
Mudford on ‘ The Agaves,’ with thirty-eight plates ; and Dr. Allen
has issued another parb of his ‘Charace®.’
Brazilian plants have received attention from Mr. S. L. Moore,
whose working up of his collections from the botanically little-
known ‘ Matto Grosso ’ came out as a thick quarto in the Linnean
Society’s Transactions, published late in December, 1895, and hence
boo late to mention in our last year’s summary. The magnificent
folio flora begun by Martins has received accessions, in |a part
devoted to the Bignoriiace® by Bureau and K. Schumann, and two
parts of the orchids by Cogniaux.
Reverting to the old world, it is extremely satisfactory to be
able to allude to the two parts of the Indian Grasses of the
‘ Flora of British India ’ which have been published lately.
After long and tedious labour the flora of British India is
approaching completion, and we may confidently expect the
last part and the general index to appear during 1897. At the
end of more than forty years’ labour Sir Joseph Hooker has the satis¬
faction of bringing his monumental labours on this subject to a
successful close. Also East Indian is Mr. Gamble’s illustrated
monograph of the bamboos, which forms part of the quartos issued
as ‘ Annals of the Calcutta Botanic Garden.’ Professor Post, of the
American Mission at Beirut has printed his ‘ Flora of Syria,
Palestine, and Sinai ’ in a handy octavo, with cuts of many of the
plants.
In Australia Professor Tate has issued a report on the Horn
Expedition to Central Australia, but we have no important work to
record from the dozen of Australian phytographers. Sir Ferdinand
von Mueller, whose recent death has left a void which we cannot,
expect to see filled again.
Signor Paolucci has produced a work on the tertiary fossils of
Ancona, and Dr. D. H. Scott is continuing his researches on the Coal-
Measures fossils in the Philosophical Transactions ; Mr. A. S. Seward
has compiled a catalogue of mezozoic plants in the British Museum*
Of works connected with gardening may be recorded Dr. Schumann’s
‘ List of Cacti in Cultivation,’ Mr. E. J. Lowe on ‘ Fern Growing,’
Professor L. Bailey on ‘ Plant Breeding,’ and Messrs. Autran and
Durand’s ‘ Hortus Boissierianus,’ a handsome octavo.
The Royal Gardens at Kew have issued three lists, the second
part of the ‘ Trees and Shrubs,’ and ‘ Conifers ’ and * Orchids.’ The
Missouri garden has printed its seventh annual report, and a thin
folio by H. Ross, gives figures and description of new plants in the
Palermo garden. Heer Paque has printed the Flemish popular
names of plants, as used in what used to be termed the Low
Countries. W e have also the ‘ Reminiscences of a Yorkshire
Naturalist,’ by Professor Williamson, completed by his widow.
Finally reference mustbemadetoDorfler’s ‘Botanists’ Address-Bc ok’
which is a great advance on anything attempted as a botanical
directory. The publication at last of the diary of Sir Joseph Banks,
edited by Sir Joseph Hooker, deserves record, while the issue of the
new edition of the Catalogue of the Linnean Society should be
mentioned, as being that of the best biological library of modem
times which exists complete in printed form.
Jan. 2, 1897] \
PHARMACEUTICAL JOURNAL
17
In reviewing this division, it cannot be said
Economic that the year has been noteworthy for bringing
Botany. to light anything remarkable either amongst
food products or articles of manufacture. From
time to time, and in various publications, a good deal of fresh
light has been thrown either upon the botanical identification of
useful plants, or upon their development and extension, or upon
their characters and properties. Early in the year the Rem
Bulletin drew attention to two African species of Holarrhena.
namely, 3. africana and H. febrifuga. It was pointed out that
the chief economic interest attached to the former was on account
of its medicinal properties, being known on the Gold Coast as a
native cure for dysentery under the name of “ Gbomi ” or “ Kpomi.”
The bark is also referred to as yielding an alkaloid similar to
conessine from the Indian species 3. antidysenterica. The plant
is confined to West Africa, ranging from Sierra Leone to the Lower
Niger. The other species, 3. febrifuga, is common in East Africa,
especially in the Zambesi region, and is known as “ Quina” by the
Portuguese. Livingstone himself used it in cases of fever,
and he says that while the native used the thick soft bark
of the root, the Portuguese used the trunk bark. A de¬
coction of it is given after the first paroxysm is over.
The continually increasing demands for Caoutchouc, or
indiarubber, has aroused a considerable amount of interest in the
new source of this article from Lagos, which came to light in 1895
as the produce of Kickxia africana, an apocynaceous plant, and so
rapid has been its development that it is estimated that the quan¬
tity now produced from this plant amounts to an average annual
value of £30,000 to £40,000. In the matter of New fruits, about
which there is a frequent complaint that India and our tropical
possessions generally do not supply our markets with any of their
produce, it may be worth recording that the attention of Kew has
-been drawn to the fruit of Rhodomyrtus tomentosa, which is known
at Ootacamund as the Hill gooseberry. The fruit is about the size of
a cherry, of a dark purple colour, and with a sweet aromatic pulp. In
India it is eaten both raw and made into jam and jelly, the latter
of which is excellent. It is suggested that in sub-tropical countries
the plant might be usefully introduced both as an ornament and
for the fruit supply. The latter could no doubt be greatly
improved by cultivation, and would be more desirable
than the Guava.
Another interesting plant brought before the notice of the Kew
authoritie s, namely, 3yoscyamus muticus, was sent by a corre¬
spondent residing at Alexandria, who said that during the summer
of 1895 he observed a native gathering seeds from a large plant near
some houses at Mex, five miles west of Alexandria. The plant, which
was three or four yards in circumference, and was in full flower, with
its handsome purple blossoms, as well as in fruit, was found to be
3. muticui. It had never been seen in this neighbourhood
before, and it is remarkable that four cases of family poisoning by
the same seeds had only just before been established. The plant
is called by the natives “ sakran,” meaning drunken, with reference
to its properties. It seems that the same name is given at Mex to
the Hyoscyamus albus, which is common there, and is used medi¬
cinally by the natives. The introduction to India and our colonies
through the instrumentality of Kew of a new species of Coffee,
known as the Highland coffee of Sierra Leone ( Coffea stenophylld),
promises to be a matter of some importance. It was fully treated
of in the Rem Bulletin for November last. Mr. Scott-Elliott, whose
travels in Tropical Africa will be fresh in the minds of our readers,
says of this coffee that it is found wild in the hills, and is more
often cultivated than the Liberian. It grows freely, and yields
quite as much as the Liberian, but is somewhat longer
in coming into bearing. Both the natives and the French traders
at Freetown say that it has a superior flavour aud prefer it to the
Liberian. He further states that some of the coffee sent to a French
dealer was sold at 4 frs. 50 cents, per lb. as “ best Mocha.” The
results of the introduction of this species to the West Indies is said
to be so far of a promising character, though the plants have not
thriven so well as could be wished in Dominica and Ceylon. The
progress of this new source of^ Coffee will be watched with interest-
Notwithstanding the introduction of Vanillin or artificially
prepared vanilla crystals, as a substitute for the true bean, there is
a continued demand for the real article. It is therefore interesting
to find that in Reunion attention has been paid to a new process of
treating vanilla pods by a M. Dolabartz, the operation of which
consists of first drying the fruits in hermetically closed vessels by
means of chloride of calcium in the proportion of about one kilo,
for every kilo, of dried vanilla obtained. The chloride of calcium
is not lost, as it can be easily regenerated by heating it in
an iron or copper receptacle. One lot of chloride of calcium
is thus sufficient for several dryings, if kept after regeneration
in an air-tight vessel. It is said that 2-981 kilos. of
raw vanilla will produce about one kilo. of the
prepared bean. It" is urged in favour of this process
that vanilla dried in an air-tight vessel loses much less vanillin
than when dried by the ordinary process, by which it is exposed to
the open air for several weeks.
With regard to the increasing and widely spreading use of Tea,
which has been condemned by some as a habit bordering on a vice,
it is worthy of note that the public expression of these opinions has
been the cause of other beverages being recommended to take the
place of the better known article. Thus a “Mat6 Tea Company ” has
recently been formed to promote the use of mate, or Paraguay tea,
as “ the only tea free from tannic acid.” We are also reminded
that this tea, which, as will be well known, is composed of the
leaves and twigs of Ilex paraguensis, has no astringency, that
“ fifty-five millions of the most healthy people in the world drink
mate tea,” and, further, that sufferers from gout, constipation,
flatulency, sleeplessness, or nerve exhaustion should drink mate,
as it will give immediate relief. At the close of another year the
Pharmaceutical Journal may have to record the general adoption
in England of Paraguay tea, but this is a fact which at present
seems extremely doubtful.
The most important practical advance in
Bacteriology, bacteriology during the present year has been
the introduction of a simple and apparently
reliable method for the diagnosis of Enteric Fever. This
method is now known as that of Widal, from its originator, and is
dependent upon a reaction originally devised by Pfeiffer, and sub¬
sequently extended by Gruber and Durham. Pfeiffer observed that
if an emulsion of cholera vibrios together with a small amount of
“cholera” antitoxic serum from a highly immunised animal be
injected into the peritoneal cavity of a normal guinea-pig, it will be
found, in about an hour’s time, that all the vibrios have become
aggregated together into spherules, whereas if, instead of the cholera
vibrios other organisms be injected, these will be unaffected.
Gruber and. Durham ( Journ . Path, and Bad., iv., 1896, p. 13^
ascertained that the same reaction occurred with Typhoid, B. coli,
and other species with their respective serums, and that in vitro a
very striking appearance was noticeable. If, for example, to an
emulsion of a typhoid culture in a test-tube a little “ typhoid ”
8erum be added, it will be found that after a variable time the
mixture becomes clear, owing to the precipitation of the bacilli as
a fiocculent deposit at the bottom of the tube. If this deposit be
examined, the bacilli will be seen to be motionless and to have
18
PHARMACEUTICAL JOURNAL.
[Jan. 2, 1897
aggregated into clumps. Widal conceived the idea that the sub¬
stance which is present in the serum employed in Pfeiffer’s re'
action, and which acts on the bacilli in the manner described,
might be formed in the body in the course of the natural disease,
and that the blood of the patient would therefore produce an effect
similar to that recorded by Gruber and Durham. In the
method employed for diagnosis the patient’s finger is
pricked and a drop or two of blood allowed to exude ; this
may be drawn up into a small glass pipette, or may be placed on a
cover-glass, on a piece of glazed paper, or on a piece of. blotting
paper and allowed to dry. It is necessary to have a young and
active culture of the typhoid bacillus, preferably a broth one. With
this a hanging drop cultivation is prepared, and to it a little of the
serum from the pipette, or when the blood has been allowed to dry
on a cover-glass or paper a solution is made by soaking in a drop
or two of sterile water, and this solution added to the hanging
drop. The preparation is then examined microscopically,
and if the case be one of enteric fever, it will be found that the
typhoid bacilli have lost their motility, and in half an hour’s time or
more clumping will be observed.
The dissemination of Enteric fever by oysters has claimed
a considerable amount of attention, and an important report
on the subject has recently been issued by the Medical Officer
of the Local Government Board; in it Dr. Bulstrode states
that few of the oyster layings, fattening beds or storage ponds
round the English and Welsh coasts can be regarded as theoreti¬
cally free from all risk of sewage pollution. Dr. Klein investigated
the matter bacteriologically, and found that the typhoid bacillus
and the cholera vibrio would live from two to four weeks in sea¬
water. Oysters were also submitted to sea-water infected with the
typhoid bacillus and with the cholera vibrio, and these organisms
could be obtained from the oysters as late as the seventeenth day
of experiment. In one case typhoid bacilli were found in an oyster
obtained from a natural source.
Lemoine (Arch. M6cL. Exper., 1896, No. 2) has investigated the
cultural and morphological differences of the various Strepto¬
cocci, and like others has come to the conclusion that these differ¬
ences are not constant and cannot be made a basis for the separation
of species. The Protozoon theory of the origin of malignant
growths has, during the present year, been relegated somewhat to
the background, and in its stead Sanfelice, Roncali, and others
have described yeast-like forms or blasto-mycetes, which have not
only been observed in the growths, but have been isolated and
cultivated, and are stated to reproduce the disease on inoculation.
Gimbert has examined the Fermentations excited by the bacillus
pneumoniae of Friedlander, and finds that it ferments not only
glucose, but galactose, arabinose, mannite, saccharose, maltose,
lactose, raffinose, dextrin and starch, glycerin and dulcite. The
fermentation products were ethyl alcohol, acetic acid, lactic acid
(lasvo-rotatory), and succinic acid. Mannite gave lactic acid (laevo-
rotatory) only, while its isomer dulcite produced succinic acid.
Although no startling discoveries in the
Pharmaeography. field of pharmacography have to be recorded,
and no new drugs possessing any remarkable
properties have been brought to the front during the past twelve
months, yet it is satisfactory to note that our knowledge of well-
known ones has made satisfactory progress, both with regard to their
constituents, their structure or mode of formation and source.
Ergot, concerning which last year interesting and important
information was communicated by Keller, has been assayed by
Beckurts, w ho finds, as the principal result of his work, that, contrary
to the opinion at present generally held, Russian and Austrian
ergot is to be preferred to German and Spanish, since the former
contain about 0‘2 per cent, of alkaloid, and the latter only about
0J5, assuming of course that the medicinal value of the ergot is
determined by the proportion of alkaloid present.
Paul and Cownley have examined Pernambuco jaborandi and its
commercial substitutes, and their assays, whilst indicating the
superiority of the Pernambuco drug show that the jaborandi
derived from Pilocarpus microphyllus is not much inferior
in the proportion of crystallisable nitrate it yields, other
varieties of jaborandi being, in this respect, comparatively
valueless. The same chemists have continued their investigations
of Ipecacuanha, and from their results it appears that, although
the Brazilian and Columbian drugs yield approximately the same
percentage of total alkaloid, the Columbian drug contains a
larger proportion of cephaeline than the Brazilian. As Wild has
found the physiological action of cephaeline to be distinct from that
of emetine, these results are of much interest and importance, for
they show that the Columbian should not be substituted for the Bra¬
zilian drug, a substitution Greenish has proved to be far from rare.
Gunn has compared a number of processes for the assay
of Coca, and finds that Lyons’ process, though it yields the best
results, is objectionable on account of the time it occupies,
and suggests a modification to remedy that defect. Browne finds
the flowers of Datura alba to contain 0 48 per cent, of an alkaloid
which he believes to be Ladenburg’s hyoscine, the identity of which,
however, requires further confirmation. Indian Hemp has again
been the subject of investigation, Marshall has extracted from it
by ether a toxid red oil which he regards as the active constituent,
and so another is added to the list of active principles that have
been isolated from this drug. Hesse has examined the root of
Rumen nepalensis and separated three crystalline bodies, one of
which is of a yellow and another of an orange colour, but neither
of them identical with the chrysophanic acid, emodin, or rhein of
rhubarb root. Naylor and Littlefield have compared Duval’s
method of extracting Cascarillin from cascarilla bark with-
Alessandri’s, and come to the conclusion that the process
advocated by the latter chemist is wholly untrustworthy.
Lloyd has determined the ash in Asafcetida, and finds that,
whilst picked tear asafoetida yields from D7'8 to 2 '55 per
cent., commercially fair samples of the drug yield from Iff
to 20 per cent., and samples of lower quality as much as 50
per cent. On the basis of these figures, which confirm pre.
vious analyses, Lloyd recommends that purified asafoetida,
should alone be employed. Schaer has presented an interesting
account of a Kino- like Product obtained from the bark of
Myristica malaharica ; it appears that this substance closely
resembles Malabar kino, although in botanical origin it is widely
different. Kiliani has investigated the reactions of some of the
constituents of Fox-glove with ferruginous sulphuric and acetic
acid, and given exact details of the means by which the most
delicate reaction for digitalin and digitoxin may be secured and
either substance detected in the presence of the other. Kiliani has
further proved the identity of his digitoxin with Schmiedeberg fe
to which a glucosidal nature is ascribed, Pellitory root has
been examined by Schneegans, and a crystalline pungent body
extracted, for which he retains the name pyrethrin ; this substance
may prove to be identical with Dunstan’s pellitorine. Interesting
results have been obtained by Hooper with Camphor oil distilled1
from the leaves of the camphor tree grown in India, those from a,
tree grown at a low elevation, yielding a large proportion of
camphor ; the production of this valuable substance may therefore
possibly be profitably be undertaken in India. From Scrophularia
nocLosa , which has long been known as a domestic medicine in
certain districts, van der Moer has isolated a yellow amorphous
Jan. 2, 1897.]
PHARMACEUTICAL JOURNAL.
toxic substance, possessing properties resembling those cf the
digitalis poisons. In connection with this investigation it is
interesting to note that attention has been drawn by Yogi to the
occurrence in the epidermis of this plant of yellow sphte-o- crystalline
masses, which he thought were probably hesperidin.
Holmes has furnished an interesting criticism of Schweinfurth’s
identification of the plant that yields Arabian Myrrh with
Commiphora abyssinica. From the absence of any bitterness'in the
bark of this plant, Holmes is led to conclude that it cannot be the
the source of Arabian myrrh, and his supposition that this drug is
probably furnished by C. myrrha receives support from the fact that
the bark of this plant alone of all examined by Holmes possessed the
bitterness and aroma characteristic of myrrh. Adulterations of
drugs have also been pointed out by Holmes, who found in a com¬
mercial sample of Blood-root no less than 40 per cent, of the
rhizome of Chamcelirium carolinianum , and detected the substitu¬
tion of the leaflets of a species of Swartzia for the small-leaved
Maranham Jaborandi ( Pilocarpus mierophyllus) .
The histological investigation of drugs has been vigorously
prosecuted, and yielded important results. After much labour
Moller has succeeded in elucidating the mystery that has long
enveloped the secretion of Storax, and proved that the injury
inflicted on the trunk by beating results in the formation of
schizogenous secretion-ducts in the young wood, and it is in these
that the storax is formed. These results may throw much light on
the production of other similar pathological secretions. Vogl has
examined and compared the structure of several varieties of
Jaborandi Leaves, and an important contribution to our know¬
ledge of the structure of some official leaves and their adulterations
has been made by Virchow, whose researches were undertaken
with the view of ascertaining whether diagnostic characters could
be found in the course of the ultimate ramifications of the veins,
and especially their terminations in the margins of the leaves. By
a long series of experiments, Virchow has shown that a further
means is here available for the identification of a leaf or the detec¬
tion of adulteration. The anatomy of cubebs forms the subject
of still one more investigation. Peinemann deals at length with
the histology of Cubebs and their substitutes, and corrects certain
details in previous descriptions of their anatomy. Latour has
communicated the results of a histological investigation of Senna
Leaves and their adulterants, and pointed out the characters that
distinguish each.
Biermann has investigated the development of the Bitter
orange, with especial reference to the formation of the oil-glands,
which he finds to be schizolysigenous. Lutz has followed the
development of the oil-glands of various species of Myrtace^e and,
finding they differ from those already known in the obliteration of
the secreting cells, has described them under the name of oblito-
schizogenous glands. In the laboratory of Tschirch, Sandarac and
Dragon s blood have been chemically examined. Balzer has shown
that Sandarac consists of 85 per cent, of sandaracolic acid and
10 per cent, of callitrolic acid, both of which he obtained in crys¬
talline form. Dieterich extracted from Dragon’s blood 13 per
cent, of a yellow and 56 per cent, of a red resin, the latter proi ing
to consist of esters of a resinotannol with benzoic and acetic acids.
Ihe literature of the subject has been augmented by the publica¬
tion of several valuable works. Planchon and Collins’ * Les Drogues
Simples contains in two volumes much that is interesting, and
Kanny Lall Dey’s ‘Indigenous Drugs of India’ will be welcome to
every pharmacognosist. The most important contribution to our
knowledge of the anatomy of drugs is that made by Tschirch and
Oesterle in the parts of their ‘Anatomical Atlas’ that have been
issued during the year.
1!)
Arsenical Soap.
Sir, — I venture to ask, is the sale of this article worth the
attention of chemists ? In the first place, its efficacy is ex¬
tremely doubtful, in vieAV of the minute quantity of arsenic shown
to exist in samples recently brought before benches of
magistrates. Should arsenical soap contain an appreciable
amount of arsenic, there is the possibility of danger from absorp¬
tion ; there is also the trouble of complying with the regulations
of the Act of Parliament respecting the sale of arsenic and its
combinations to be considered, and all to encourage
the sale of an article of doubtful efficacy, which may be
a dangerous application. It has been alleged that at least one.
sample of a so-called arsenical soap did not contain a trace of
arsenic, and the sale of this looks very like a fraud on credulous
purchasers.
Knightsbridge, December 26, 1896. J. B. Barnes.
Manchester Pharmaceutical Association.
Sir, — May I be allowed in reply to “ Your Contributor ” (72/6)
to say that Mr. G. Wilkinson’s statement in regard to this Asso¬
ciation is quite correct ? The Association was originally formed in
1852, with the title of “ The Manchester Chemists’ Conversational
Society” and under various titles and with very fluctuating
fortunes ; from that time until the formation of the present Asso¬
ciation it never entirely ceased to exist. It is true that after about
the year 1859 no meetings were held and no reports published, but
there were always two or three who kept up the name of the
Association and would not allow it to die out entirely, and were in
readiness to take action in the event of any measure being proposed
affecting the interests of the trade. I may say, also, that the men
who had been most earnest in the support of the old Association
were amongst the most active in the formation of the new one,
and may fairly claim a continuous existence for their old organ isa .
tion.
Cheetham Hill, December 21. W. Wilkinson..
A Correction.
Sir,— A notice having appeared in one of the trade journals to
the effect that our business has been transferred to “May and
Baker, Ltd.,” we shall esteem it a favour if you will enable us, by
the insertion of this letter in your next issue, to inform our friends
that such is not the case, and that we have no intention of making
any change of the kind. The confusion may have arisen through
our transferring our cyanide manufacture to the above firm, but
nothing more has been or will be so transferred.
23, Cross Street, Finsbury, E.C. Johnson and Sons, Ltd.
December 28, 1896.
The Irish Licence Examination.
Sir, — The Registrar of the Pharmaceutical Society of Ireland,,
not having denied my statement re the Irish licence examination,
which appeared in your issue of the 12th inst. , he leaves your readers
to conclude that an undoubted grievance exists. I trust Dr. Duffey,
the courteous and watchful Government Visitor, will, in his comi ng
yearly report, have this matter remedied. The -present council is
a far too Conservative body, and until some Radical blood is intro¬
duced, no useful reforms need be expected. Since I wrote last, I
see several licentiates have resigned membership. Why is this ?
The reasons are only too self-evident. Just look at the splendid
circulating pharmaceutical library at Bloomsbury Square, for
English and Scotch students ; then cast your gaze at the bare walls
of Mount Street, and remember it is not for lack of funds. The
other week at Edinburgh, Messrs. Ewing, Storrar and Tocher,
spoke humorously regarding pharmaceutical Home Rule for Scotland.
I sincerely trust they will never have it ; the decision of the Irish
pharmacists in 1868, in that respect, is now found out to be
Ireland’s bane.
Belfast, December 21, 1896. “ Vim et Verve.” (73/14)
Elder Flower Ointment.
Sir, — In your last issue Mr. J. F. Brown refers to the difficulty of
preserving elder flower ointment duringthe twelve months that must
elapse between the periods of its preparation from fresh flowers.
He suggests the preparation by enfleurage of an elder flower
pomade, but a still more convenient way out of the difficulty is the
use of the otto of elder blossoms. This is distilled from the flowers
20
PHARMACEUTICAL JOURNAL.
[Jan. 2, 1897
like otto of roses, and, like it, is solid at ordinary temperatures, its
melting point being 28° C. It consists of a fragrant liquid oil
with an odourless stearopten almost insoluble in alcohol. It is
soluble in fats, and possesses the exact aroma of the flowers. The
yield from the flowers is extremely small, and the cost of the oil is
approximately the same as that of otto of roses, but like this latter
body, a little goes a long way, and a grain of the oil is sufficient to
give a very distinct perfume of elder flowers to a Jib. of lard.
Artillery Lane, London, W. J. Bush* and Co.
December 29, 1896.
Benevolent Fund.
Sir, — I am convinced that the idea of a “Christmas box sub¬
scription ” (as an effort separate from the regular subscriptions to
the Benevolent Fund) is one that will readily respond to cultiva¬
tion. The one thing needful is a personal call. May I suggest
that in order to keep the ball rolling an official communication be
addressed to all local and divisional secretaries early each December
asking them to endeavour, by means of a personal call, to induce
every chemist and assistant in their respective districts to sub¬
scribe a shilling to the Fund ? I have just been round here, and
practically every chemist and assistant in North Paddington has
immediately joined in the subscription ; the result is 35 s. (which I
enclose) for the Benevolent Fund just for the asking. Even those
who are already subscribers have willingly added extra shillings,
and others who ‘ ‘ don’t take any interest in the Fund and don’t
care ‘ tuppence ’ about the Society ” seemed quite pleased to add
their shillings for the benefit of the widow and the fatherless.
Imagine every chemist and assistant throughout Great Britain joining
hands at Christmas and giving a shilling each to help those of us who
are in need ! The idea is sublime, and I feel sure that no local or
divisional secretary would fail to do his share towards its realisa¬
tion.
35, Clifton Road, Maida Vale, W. , R. H. Parker.
December 29, 1896.
V* V e are mush indebted to Mr. Parker for Ms practical demonstration that
the suggestion made in the Journal of December 19 was a feasible one. —
[Ed. Pharm. Journ.]
Paraf. Javal’s Solution.
Sir,— Can any reader give me the formula for Paraf. Javal’s
solution of strontium iodide ?
December 13, 1S96. “Pharmacist” (71/27).
Overpaid Income Tax.
Sir, — Now that those of your readers who are engaged in busi¬
ness are ascertaining the amount of their profits for the past year,
will you allow us to remind them that, if such profits show a
diminution they may be entitled to the repayment of a considerable
portion of the Income Tax paid in respect of the same and to point
out the importance of making the claim forthwith. Not only can they
claim the difference named, but if the average is there¬
by reduced to the limits of exemption or abatement they can
obtain additional relief. Thousands of people pay tax for which
they are not liable, more particularly those whose incomes are
derived from investments where tax is deducted before being paid
to the recipients ; partners who have been assessed jointly with
the firm, but whose separate incomes are such as to entitle them to
relief ; and married women having incomes derived from a profes¬
sion, employment or vocation where the total joint income does
not exceed £500.
With few exceptions, which need not be mentioned, all persons
whose incomes for the year ending April 5, 1894, were under £400,
and tuose whose incomes did not exceed £500 per annum for the
two years ending April 5, 1896, can still claim repayment of tax
deducted from rents, interest or dividends, even when the latter
are said to be “free of income-tax.” Claims can in many cases
now be made for four years, and the sum repayable might exceed
£36 up to the end of the current financial year, to say nothing of
tax allowed in respect of life assurance premiums, even when the
income exceeds £500.
We shall be glad to advise any of your readers gratuitously
whether they can make a claim, if they send us full particulars of
their incomes and a stamped addressed envelope.
12 and 13, Poultry, London, E. C. ,
January 1, 1897. The Income-Tax Adjustment Agency.
ANSWERS TO QUERIES.
Oak Varnish. — Pale clear resin, 6 ounces ; sandarach, 2 ounces ;
turpentine, 24 ounces ; dissolve. [ Reply to “ Old Reader.’’ — 73/38. ]
Book on the “X” Rays. — See “Practical Radiography,” by
H. Snowden Ward (Dawburn and Ward, Ltd., 6. Farringdon Avenue,
E.C. Price Is. 2d., post free). You will observe that we are publish¬
ing a series of articles on the same subject, intended to cover the
whole ground in a practical manner. [Reply to Thorax. — 72/35.]
Kopp’s Syrup Maker and Filter. — We doubt if this apparatus
is yet obtainable in this country. Inquire of Maw, Son and Thomp¬
son and other dealers in druggist’s sundries, referring them to our
pages for particulars. You might also write direct to Strasburg
for a price-list. [Reply to J. W. and Co. — 73/22.]
Mahogany Varnish. — Gum sandarach, 2 ozs. ; shellac, 1 oz. ;
benzoin, J oz. ; Venice turpentine, 1 oz. ; powdered glass, 1 oz. ;
methylated spirit, 20 fl. ozs. ; dragon’s blood sufficient to tint.
Let stand in a warm place in a well-corked bottle with frequent
shaking until the gums are dissolved, then allow to settle down
bright. [Reply to Old Reader. — 73/38.]
Red Furniture Cream.— Beeswax, 7 ounces ; soap, f ounce ;
pearlashes, 2 drachms ; turpentine, 10 ounces ; water, 10 ounces ;
powdered dragon’s blood, q.s. to colour. Add the dragon’s blood
and wax to the turps, warm, till the wax is dissolved. Heat the
soap and pearlashes in the water till dissolved ; then mix and stir
till cold. [Reply to “ Old Reader.” — 73/38.]
Assay of Extract of Nux Vomica.— In the official directions
in the first paragraph, you will note that the chloroform is added
first to the acid liquid. This chloroform is then rejected, as the
alkaloids remain behind as acid salts. It removes fatty matter and
resinoid colouring bodies. The acid liquid is made alkaline and
again shaken with chloroform, which removes the alkaloids. The
process hinges on the fact that alkaloids are not removed from
acid liquids by chloroform, but are dissolved out by it from alka¬
line ones. In other words, the salts of the alkaloids are more
soluble in water than in chloroform, but the free alkaloids them¬
selves are, in this and many other instances, more soluble in
chloroform than in water. [Reply to G. W. G. — 70/37.]
OBITUARY.
Roberts. — On December 17, Thomas Roberts, Chemist and
Druggist, of Manchester.
Davies. -r-On December 21, William Evans Davies, Chemist and
Druggist, of Cardiff. Aged 52.
Baker. — On December 23, Frank Baker, Chemist and Druggist,
Sandwich, aged 55. Mr. Baker was a member of the Pharma¬
ceutical Society, having been in business before the passing of
the Pharmacy Act, 1868. He was elected on the Sandwich Town
Council in 1871, was chosen Mayor in 1876 and the following
year, became an Alderman in 1881, and at the time of his death
was the oldest member of the Council. Mr. Baker was also one
of the trustees of the Municipal Charities and a borough
magistrate.
Schacht. — On December 26, George Frederick Schacht, Pharma¬
ceutical Chemist, of Clifton. Aged 73.
PUBLISHERS’ NOTICE.
COVERS FOR BINDING.
Cloth gilt-lettered covers for binding the half-yearly volume of
the Pharmaceutical Journal are supplied by the Publishers, at
a charge, including postage, of Is. 6 d. each.
All Orders and Remittances should be Sent to the
Publishers, 5, Serle Street, London, W.C.
COMMUNICATIONS, LETTERS, etc., have been received from
Messrs. Barnes, Blackwell, Blunt, Bowden, Bush, Butler? Cook,
Dott, Duncan, Evans, Fletcher, Gadd, Giliaddison, Goldby,
Hayes, Hogg, Holmes, Howe, Keen, Parker, Ridyard, Russell,
Spilsbury, Weddell, Wiggins, Williams.
Jan. 9, 1897]
PHARMACEUTICAL JOURNAL.
21
HOMOLOGUES OF CAFFEINE.*
One of Professor Schmidt’s studentst has taken up the investiga¬
tion of these compounds to complete the somewhat imperfect
account given of ethyl-theobromine by L. Philips, J and prepared
according to Strecker’s caffeine synthesis, by acting upon theo¬
bromine silver with ethyl iodide.
The production of ethyl-theobromine was effected by the method
applied by E. Schmidt and H. Pressler§ for converting theobromine
into caffeine, a mixture of the potassium compound of theobromine
with an alcoholic solution of ethyl iodide, being heated for six hours
on a water bath in a flask capable of bearing pressure. The
product of the reaction was then mixed with water, the filtered
solution evaporated, and the residue extracted with chloroform.
In this way a satisfactory yield of ethyl-theobromine or homo¬
caffeine was obtained.
Ethyl-Theobromine forms anhydrous silky crystals, and is
capable of being sublimed when cautiously heated. Its solubilility
in various menstrua closely resembles that of caffeine. The melt¬
ing point is from 164° to 165° C., though Philips has stated it is
above 270° C.
The reaction of ethyl-theobromine with chlorine water and
ammonia is similar to that of caffeine, and is due to formation of
amalic acid. The salts of ethyl-theobromine also resemble those
of caffeine in being decomposed by solution in water so completely
that the amount of acid in any of the salts may be ascertained by
titration with decinormal alkali solution. The following salts
were prepared and examined : —
Hydrochloride , C7H7(C2H5)N402,HC1 + 2H20. — Acicular crystals,
losing their water at 100° to 120° C. , and also the whole of the
hydrochloric acid.
Hydrobromide, C7H7(C JL )N402, HBr. — Transparent needles.
Acetate, C7H7(C2H5)N402(C2H402)2. — Transparent needles, losing
the whole of their acid at 100° C.
The gold chloride salt melts at 226° C., the platino chloride above
240° C. Both the hydrargyro chloride and the hydrargyro cyanide
crystallise in needles. The compound with silver nitrate,
C7H7(C2H5)N402,AgN03, forms fine long needles.
By reaction with methyl iodide ethyl-theobromine is converted
into the compound C7H7(C2H.)N402-CH3I. The corresponding
chloride yields well-defined crystalline compounds with platinum
chloride and with gold chloride [CyH^CjjHg^CVCHjPP-f Cl4,
melting at 232° C., and C7H7(C.H5 )N4Oa -CH3C1 + AuC13, melting at
215° C. Ethyl iodide does not react with ethyl-theobromine any
more than it does with caffeine.
By the action of an equivalent proportion of caustic potash ethyl-
theobromine is converted into homo-coffeidine carbonic acid,
C8H14N403, which can be identified by means of its characteristic
copper salt (C9H13N403)2Cu + 4H20.
Bromine converts ethyl-theobromine into monobrom-ethyl-theo-
bromine, C7H6Br(C2H5)N402, which is precipitated from solution in
strong hydrochloric acid, on addition of water, in small colourless
crystals, melting at 171° to 172° C. When this compound is heated
with alcoholic potash it is converted into ethoxy-ethyl-theobromine,
C7H7(C2H6)N402 0-C2u, in the form of sparingly soluble crystals
melting at 154° C.
By oxidation with potassium bichromate and sulphuric acid,
ethyl-theobromine yields ammonia, methylamine and finely
crystallisable ethyl-methyl parabanic acid, C3(C2H8)(CH3)N203,
which melts at 44° C. and is resolved into ethyl-methyl urea and
oxalic acid by the action of caustic potash. By heating with
* Apothelcer Zeitung, xii., 5.
t W. van der Stoolen. — Inaugural Dissertation, Marburg, 1895.
4 Bericht.e, ix., 1308. § Liebig’s Annalen, 217, 294.
Yol. LVIII. (Fourth Series, Vol. IV.}. No. 1385.
nitric acid (s.g. 1'4) ethyl-theobromine is converted into ethyl-
methyl parabanic acid and methylamine. An intermediate
product similar to amalic acid appears to be formed in this reaction.
Potassium chlorate and hydrochloric acid convert ethyl-theo¬
bromine partly into monochlorethyl-theobromine, C7H6Cl(CiH )
N402, melting at 141° C. By further action syrupy ethylmethyl-
alloxan is formed which gives a crystallisable compound with
potassium bisulphate, C7H8N204‘KHS04, and ethyl-apotheobromine,
CgllgN.jOr,, melting at 137° to 138° C. This reaction supports the
structural formula suggested by E. Fischer for theobromine in
regard to the position of the remaining NH. group.
Propyl-Theobromine, C7H7(C3H7)N402, is formed in the same
manner as ethyl-theobromine : it crystallises in needles, melts at
136° C., and can be sublimed by cautious heating.
Isobutyl-Theobromine, C7H7(C4H9)N402, forms white needles
very sparingly, soluble in cold water, and melting at 129 to 130° C.
With chlorine water and ammonia they give the amalic acid
reaction. The gold and platinum double salts of both the last-
named caffeine homologues are crystallisable.
NOTE ON THE DRYING OF ALKALOIDS AND
THEIR SALTS.
BY D. B. DOTT.
There has lately been discussion as to the proper temperature
and time of exposure to be observed in drying the alkaloids and
their salts, when these are being estimated by the pharmacopceial
methods. Drying in the water bath is, no doubt, the most con¬
venient course, and should be adopted when not contra-indicated.
But it must be borne in mind that the “ temperature of a water
bath ” is not a constant, but varies according to circumstances.
The larger the bath the lower the temperature, for the heating
surface does not increase in anything like the ratio of the cubic
space. A bath which has almost no ventilation will
attain a higher temperature than one which is suit¬
ably ventilated for the drying of moist precipitates. With
only a little water in the bath the temperature will not rise so
high as when well filled with boiling water. Wherefore it is
evident that a substance which does not readily part with its water
a few degrees below 100° C. should not be directed to be dried in
the water bath, but in an air bath or otherwise at a temperature
over 100°. Morphine hydrate is such a substance. In a copper
water bath of ordinary construction, 10 inches internal measure¬
ment, pure morphine hydrate in fine powder lost after two hours
3 31 per cent., after three hours 3 56 per cent., the bath being well
filled with water briskly boiling. The morphine was then transferred
to the air bath at 120° for one hour, when it indicated a loss of
6 35 per cent., and lost nothing further. 8C17H19N03,9H20 requires
6 ‘63 per cent, loss on complete desiccation. Another sample dried
in the water bath containing very little water, had lost after two
hours only -17 per cent., then on drying at 120° indicated 6 "49 per
cent. The morphine precipitates of the Pharmacopoeia ought
therefore to be dried either at a low temperature (as U.S.P. ), or at
110° to 120° C., and not in a water bath.
Quinine hydrate exposed for three hours in the water bath
lost nothing further at 120° C. , yet it does not follow that a
temperature under 100° is to be adopted for drying
quinine. When an alkaloid has been extracted by alcohol
or chloroform, it may only slowly attain a constant weight
in the water bath, for reasons partly physical and partly chemical.
In such cases it is much more convenient to dry at 110° to 120^,
assuming that there is no decomposition at the higher tempera¬
ture. Quinine sulphate lost 14 43 per cent, by drying in the
water bath for three hours, and nothing more, in the air bath ah
22
PHARMACEUTICAL JOURNAL.
[Jan. 9 i897
120° C. There are several salts which lose only a proportion of
their water under 100° C., and the remainder at a higher tempera¬
ture. In these cases it would, as a rule, be preferable to dry at the
higher temperature, so as to estimate the total water of hydration.
PRACTICAL RADIOGRAPHY.
Fig. I.
II.— THE SOURCE OF ELECTRICITY.
Before leaving the subject of the induction coil (see last volume,
p. 526) it must be pointed out that there is one thing which should
always be fitted (to large coils, that is a commutator or current
reverser, for though not essential to the working of the coil, it will
be found a great convenience. As a rule it takes the form of an
ebonite cylinder, on oppo¬
site sides of which are ^ 1 1 v s |
fixed two brass plates in
connection with the up¬
rights supporting the cy¬
linder. These, again, are
connected with the wires
from the battery, as shown
in the accompanying
sketch, in which P P are
the batteries with the wires connected to the supports (Sx S2) of the
cylinder. T2 are contact springs which are, as shown, connected
with the two ends of the primary coil through the contact breaker,
BR, and condensers, C N. It is obvious
that if the commutator is turned with the
ebonite touching the springs, Tj T2, no
current will pass ; but if it be turned one
quarter of a revolution the electricity may
be caused to flow in either direction, and
ij. this saves the necessity of disconnecting
the wires from the batteries and reversing
their positions with respect to the primary }
which is a saving of time and trouble,
whilst a ready means is also afforded of cutting off the current.
We now come to the source of electricity ; this may take the
form of a primary battery or an accumulator. The most useful forms
are the bichromate, the Bunsen, the Grove, and the Edison-Lalande.
The Bichromate Battery.
The bichromate battery is fairly familiar to all in its normal
bottle shape, and consists of a zinc rod between two sheets of
carbon immersed in a liquid composed either of bichromate of
potash, 6 ozs. ; hot water, 2 pints; sulphuric acid, 6 ozs.;
or else chromic acid may be obtained commercially, which merely
requires dissolving in water to form the exciting fluid. A much
more convenient form than the bottle for portability is the squat
square-shaped glass jar shown in Fig. 2, in which the internal
arrangements are precisely the same as already described.
The Bunsen Battery.
The Bunsen battery is very satis¬
factory in working, except that it
gives off fumes which are extremely
unpleasant. It consists of a glazed
stoneware jar, in which is a cylinder
(Fig. 3) of zinc, which is the negative
element, and inside this a porous pot
containing a bar of carbon, which is
the positive element. The exciting
fluid is strong nitric acid for the car¬
bon, and a 10 per cent, solution of sul¬
phuric acid for the zinc which should
be amalgamated.
Fig. 2.
The Grove Battery.
This is almost identical with the Bunsen, only a platinum or
platinised silver plate is used instead of the carbon. Of the two,
as a rule the Bunsen is to be preferred, because its prime cost is
less, and it costs less to maintain, and the difference as regards
efficiency is negligible.
The Edison-Lalande Battery.
This is preferable to all the others, and curiously enough seems
but little known, but from its great constancy, low internal re¬
sistance, and absence from local action is deserving of better notice.
It is usually a porcelain or glass jar
with zinc as the positive element and
plates of black oxide of copper, CuO as
the negative, the exciting solution being
a 25 per cent, solution of caustic potash.
The zincs are amalgamated, and
thicker at the top than the bottom.
The action of this cell is as follows : — ■
When the circuit is closed the water
is decomposed, the oxygen combining
with the zinc to form oxide, which dis¬
solves in and combines with the caustic
potash, and the hydrogen liberated from
the water combining with the oxygen
of the copper oxide, reducing it to a
very pure metallic state. As a rule it is
advisable to cover the top of the solu¬
tion with about half an inch of heavy
paraffin oil to prevent the “creeping” of the liquid. One great
advantage of this battery is that when not in use it can be merely
set on one side and left for months without suffering any deterio¬
ration or causing trouble of any kind.
The number of cells used will of course depend upon the current
that is wanted, but it may be assumed that six quart bichromates,
five or six Bunsen and Grove, or an Edison-Lalande, No. 2, of 300
ampere hours’ capacity, measuring 5| x 3f inches, will be about
right for a 4 or 6 inch spark coil. The cells may be increased in
number, but it must not be forgotten that to do this means increas¬
ing the risk of breaking down the insulation somewhere.
The Use of Accumulators.
Accumulators may be used, and frequently are, by lecturers
who find it necessary to travel, but whilst called accumulators it
must not be forgotten that they are really batteries, though of a
somewffiat different type to the others, and from some experience
it has been found that the Edison-Lalande battery is more con¬
venient because it need not be charged till just before the lecture,
and can be carried about dry, whereas accumulators if at all strained
t/namc
fto.
ft
-f
H,SO,
will readily leak and not
only make a mess but
prove to be deficient in
current at a critical time.
An accumulator, as al¬
ready stated, is a battery,
and is sometimes called a
secondary or storage bat¬
tery. Its action is very
simple when understood.
If we take two sheets of
lead and suspend them in
a solution which does not
attack them, such as
electricity
Fig. 5. attack them, such as Fig. 6.
dilute sulphuric acid, there is no electricity generated, but
supposing we have an outside generating current and pass it into
Jan. 9, 1897.]
PHARMACEUTICAL JOURNAL.
23
such a cell by one of the plates through the solution into the
other, chemical action is set up, and the plates are affected. A
simple form of storage battery is shown in Fig. 5, and consists of
two plates of lead, AB, immersed in sulphuric acid and connected
to a dynamo. The current flows in the direction of the arrow into
A, through the acid to B, and thence back again, when peroxide of
lead, PbOs, and spongy lead are formed. When the cell is fully
charged and the two -wires are connected with a lamp, or the cir¬
cuit is otherwise closed, one atom of oxygen from the Pb02 unites
with the spongy lead and PbO is formed, this going on
with the generation of a current of electricity, till both plates are
converted into PbO, when the cell is exhausted and must be
recharged. It will be seen from this that we do not actually store
electricity, but convert the cell into a primary battery, and it will
also be noted that the cell is discharged in a contrary direction to
that in which it receives the current.
The Wimshurst or Influence Machine.
Soon after Rontgen’s announcement many tried the Wimshurst
or influence machine for X ray work with varying results, but now
there is no doubt that with certain precautions and care as good
results may be obtained by it as by the coil, but it is doubtful
whether in as brief time. Reports upon this point are a little
Qontradictory, and when cost is taken into account there is not
much to choose between the two, whilst a Wimshurst is almost
worse to carry about than a coil and batteries.
The principle involved in a Wimshurst or influence machine is
exceedingly simple. If we take a smooth glass rod and rub it
with a silk handkerchief, the glass rod becomes charged with
negative electricity on its surface, and this can be made manifest
by the attraction of small pieces of paper lying on a table.
In precisely the same way we can excite a stick of sealing-wax by
rubbing it with flannel, but it will be found that in this case
the sealing-wax is charged with positive electricity. As the glass
and sealing-wax become charged or excited the rubbing material
is also excited with the opposite electricity. Thus in the case of
the silk and glass the silk is positively charged.
As it would be impossible by any ordinary means of rubbing to
excite sufficient current to produce a spark of any length,
the Wimshurst machines are used. No further description of
these is required, and the general form is shown in Fig. 7. From
an examination of this figure it will be seen that there are sets of
combs which collect the electricity from the glass, and from one
of these sets, if the machine is worked in the dark, a peculiar
brush-like discharge will be seen to take place over the surface of
the glass, whilst at the other will be mere stars or spots of light.
This brush discharge is positive and the anode of the Crookes
tube must be connected with the discharging terminal. It is
usual in all Wimshursts to have two Leyden jars affixed to the
base, which act as condensers, but for X ray work these should be
omitted, as they make the discharge too intermittent. The use
of a Tesla coil and the current from the street mains will be
considered in the next article.
PROPRIETARY ARTICLES TRADE ASSOCIATION.
BY W. S. GLYN- JONES.
Unless the Editor has a somewhat liberal conception of concise¬
ness, I fear he has set me a difficult task in asking me to write
“a concise account of the aims and objects of the P.A.T.A. , making
the most of its claims to the support of chemists and druggists,
and showing both what has been accomplished and what yet
remains to be done.” The Association has been in existence just
one year. Like the majority of my brother chemists, I have for
some time past felt the necessity for curtailing the ruinous com¬
petition in what unfortunately constitutes so large a proportion of
our business— -that is, the sale of proprietary articles — believing
that, if the assistance of the proprietors of the articles in question
could be enlisted, prices could be controlled. After securing the
co-operation of the principal wholesale houses, I approached a
number of the proprietors, with the result that the P.A.T.A. was
formed. I mention this in order to show that the Association is
not a manufacturer’s or wholesaler’s movement. That they each ■
have something to gain, so far from being denied, is affirmed, as a
reason for anticipating hopeful results. The objects as stated in
the rules are as follow : —
(o) The discussion of matters of common interest to the branches of the trades
represented, with a view to decision, and, if necessary, concerted action.
(6) To take such steps as the Association may he advised are legal to deal with
extreme cutting of prices, and to give advice and render assistance to its
members in preventing substitution.
(c) To do all such other things as may appear to be of benefit to the trade.
It will be noticed that they are sufficiently far reaching. The
prevention of cutting is, of course, our chief object, though it is
open to either of the three sections of the Association — proprietors,
wholesalers, or retailers — to take up any other matter upon which
concerted action should be thought desirable. The mention of
substitution in paragraph (b) requires, perhaps, some explanation.
The term is used in the sense of describing a growing practice
amongst retailers, by which, without the slightest fraudulent
deception, every endeavour is used to induce customers to accept,
in lieu of the advertised article they inquire for, and which would
be sold at an infinitesimal profit, a similar article, upon which
the retailer is enabled to secure an adequate return. It is main¬
tained that this practice is due to the fact that the business in
advertised proprietaries is conducted at almost cost price, and if
the proprietors ensured on the distribution of their goods an adequate
profit, they would be removing the necessity for this substitution.
Hence the ground of our appeal to proprietors. I would especially
point out that no compulsory undertaking is asked of retailers as to
pushing their own or other preparations in the place of protected
articles. They arc not asked to pledge themselves, against their
will, not to substitute. On the other hand, it is contended that
where a fair profit is guaranteed substitution does not pay, and
24
PHARMACEUTICAL JOURNAL.
[Jan. 9, 1897
that this fact alone safeguards the interests of proprietors on
our list. That this is so is proved by the fact that so many
retailers have written to the proprietors of the articles
on our list, volunteering the statement that they always
hand their articles to customers who ask for them
without attempting, as they formerly did, to. sell a rival
article. The plan by which prices are secured is simple, and
obviates the very great difficulties and annoyances experienced,
especially by the wholesale trade, owing to the various separate
agreements issued by an ever-increasing number of individual pro¬
prietors. The proprietors of the articles upon our list undertake
to withhold supplies of their articles from any firm selling any one
of them below the minimum prices, or from any firm who after due
notice supplies such a cutter with any of the goods. Retailers
buying through the wholesale houses are not required to give
agreements, but immediately information of their cutting reaches
the Association, their names are sent to the proprietors and to the
wholesale trade, and supplies of the whole list withheld until the
correct prices are maintained. Our list, which is being added to
each month, includes the following articles
Aston’s Sovereign Embrocation.
Barclay’s Dr. Bateman’s Drops.
Beetham’s Anodyne Lotion.
,, Capillary Fluid and Hair
Grower.
,, Corn Plaster.
Glycerine and Cucumb3r,
,, Indel. Extract.
,, Soft Corn Cure.
Benbow’s Dog Mixture.
Condal Water.
Davis's Calorific.
,, ,, Shields.
Dicey’s Dr. Bateman’s Drop’.
,, Daffy’s Elixir.
Dredge's Heal-All.
Frog in Your Throat ?
G-ell’s Foot-Bot Ointment.
Oaraudel’s Pastilles.
Hall’s Coca Wine.
“ H.O.”
Hayman’s Balsam of Horehound.
Invalid Bjvril.
Kearsley’s Original WidowWelch’s Pills.
Mrs. Johnson’s American Soothing
Syrup.
Lambert’s Balsam.
Lascelles’ Pills.
Liebig’s Ext. of Meat and Malt Wine
(Keystone Brand).
Liebig Co.’s Ext. of Meat.
Moller’s New Hydroxyl-free Cod-liver
Oil.
Peptarnis (Liebig Co.’s Peptone of
Beef).
Powell’s Balsam of Aniseed.
,, Mild Aperient Pills.
Dr. Scott’s Bilious and Liver Pills.
Smedley’s Chillie Paste.
Standard Malt Extract.
Standard Liquid Malt Extract.
Vitalia Meat Juice.
Webster’s' Manilla Paper.
Zox.
„ Plasters.
,, Tonic.
Further additions will be made this month. Over 1700 retailers
have been enrolled, and our list of wholesale members includes
(with the exception of Messrs. Newbery) every wholesale patent
medicine house in London ; together with the following country
firms, Messrs. Bleasdale, Ltd., York; Evans, Gadd, and Co.,
Exeter ; Hirst, Brooke, and Hirst, Leeds ; Morris and Jones, Liver¬
pool ; Southall Bros, and Barclay, Birmingham ; W oolleys,
Alan Chester, and Wyleys, Coventry.
So much for what we have done. It is a year’s record of which
I maintain we have every reason to be proud, and one which
should establish our claims to the supjoort of all retail chemists,
who in this matter have everything to gain and nothing to lose by
supporting the movement. Much as some may regret the fact,
proprietary articles of a medicinal character are in great demand.
They are consumed by the “drug-taking” public, our customers,
and if we are not in a position to meet that demand we lose our
clientele. Two reasons are often given for not supporting us.
First. — “My business is of a high-class character, chiefly dispens¬
ing, and I sell no quack nostrums.” If there were no proprietaries
other than quack nostrums this objection would perhaps hold good.
Your article on “Th e Pharmaceutical Journal and Changed Ideals,”
(page 12), may be referred to here in reference to this point.
Invalid preparations, toilet specialties, mineral waters, all come
under the heading of proprietary articles and within the scope of
the enterprising cutter. No pharmacist, however high class his
business, can afford to ignore the fact that his position as a
trader in these articles is being undermined by his store com¬
petitors, and that he risks the loss of his dispensing by being
undersold in the other branches of his business. Apart from this,
freedom from the annoyance of constant bickering and grumbling
as to prices for these articles, and the knowledge that in charging
a certain amount no underselling can take place, are in themselves
desirable apart from any pecuniary advantage. The chemist who,
whilst laying claim to the highest class of business, offers as an
excuse for his lukewarmness to our movement that his trade in
proprietaries is so small, apparently forgets that it is in all proba¬
bility due to the underselling of his neighbours, and that if such
cutting were prevented, his share in the trade of these goods
would be increased. That this is the result of protected prices
has been proved in the cases of articles upon our list.
Second Objection. — The man who says he prefers selling his own
' preparations whether he makes a profit or not upon an advertised
article, and urges this as an objection to our Association, seems to
overlook the fact that by joining our movement he is quite at liberty
to push his own articles, though I maintain he will find it better
business to sell the article he is asked for, provided the trans¬
action shows a fair profit, than to risk offending the customer by
pressing him to take something in its place.
Our prospects are just what retail chemists and druggists choose
to make them. The principal obstacle in the way of an increased
list, the chief weapon in the hands of the cutters who are opposing
us, is that we do not speak for the trade. A number of leading
proprietors have promised to add their articles directly a fair
proportion of the trade show their desire for such a step
by becoming members of the Association. No better
evidence of the possibilities of our Association can be afforded
than the evident concern shown by the big cutting houses*
and the astonishing efforts they have been, making to
thwart us. If the rank and file of the trade only showed a tithe
of the energy in supporting us that has been forthcoming from
the enemies of the trade in opposition to our work a vast amount
could be done by way of curtailing the insane competition which
to-day is playing such great havoc with the business of our
fellow-craftsmen. A suggestion that our work is in opposition
to the work of the Pharmaceutical Society may at once be dis¬
missed. The objects of the P.A. T.A. are of a character which it
would be impossible for the Society to deal with. In an article of
this description it is impossible to go into detail, but I should be
glad at all times to be able to afford any other information that
may be thought desirable. The retail subscription to the Associa¬
tion is 5s. a year. . It should be sent to the Secretary, 2 and 3,
Stonecutter Street, London, E.C.
Citrates of Phenetidine. — By heating together a mixture of
citric acid and para-amidophenetol at a temperature from
100°-200°, Heyden has obtained two compounds of citric acid with
the phenetidine radical, one mono-, the otlfer di-basic. The former
occurs as a white crystalline powder or in large crystals melting at
72°, readily soluble in warm water, and having an acid reaction
Solution of sodium carbonate dissolves it with effervescence.
Heated to 100° it loses a molecule of water, and then does not
melt below 120°. The dibasic bod}7 is a white powder with an acid
reaction, only slightly soluble in water, melting at 177°. Solution
of sodium carbonate does not dissolve it until heated. Both these
bodies possess analgesic and antipyretic properties, which are
more promptly manifested than in the case of phenacetine or lacto-
phenine. — Journ. de Pharm. d’ Anvers, lii. , after Pharmaceut. Post.
Jan. 9, 1897J
PHARMACEUTICAL JOURNAL*
25
GELATIN CAPSULES.*
BY WM, C. ALrERS.
1. History of the Capsule.
Daring the last fifty years, the filled and empty gelatin capsules
have become of such general use among physicians and pharmacists,
that a short history of their origin and development may not be
without interest. Oar Pharmacopoeia ignores them entirely, and
the various handbooks on pharmacy contain but very scant infor¬
mation on this useful article.
In compiling the following notes, the writer consulted the
libraries, public and private, of New Yoik, as far as they were
accessible, and while he thinks that he has recorded all that is
desirable to know on this subject, he cannot claim that nothing has
been overlooked or forgotten, and will be glad to receive additions
or corrections. He is greatly indebted for much valuable informa¬
tion to the firms of H. Planten and Co. and E. Fougera and Co., of
New York ; to Parke, Davis, and Co. and the Merz Capsule Co., of
Detroit, Mich., and to the authors of the various pharmaceutical
manuals.
The gelatin capsule was invented by Mr. A. Mothes, a French
pharmacist, in 1833. Experiments had evidently been made before,
but no evidence of success nor public acknowledgment can be
found before this date. Official notice of the discovery was taken
by two reports to the “ Acad<§mie royale de Medecine,” one on May,
13, 1834, the other on February 28, 1837, both of which speak
approvingly of it. On March 15, 1837, Dr. M. F. Ratier, a prominent
physician and teacher of Paris, inserted in the ‘ Dictionnaire de
Medecine et de Chirurgie practiques’ (volume xv., page 285) an
article on “ Therebinthine de Copahu,” in which he speaks of the
happy idea of the gelatin capsules which admit of direct adminis¬
tration of either balsam of copaiva or its volatile oil without any
addition liable to alter its virtues. There is therefore no doubt that
this invention was at once welcomed by the medical and pharma¬
ceutical professions as a safe method of administering nauseating
liquids. The capsules were known after their inventor as “ Capsules
Gelatineuses de Mothes,” and were manufactured and sold by the
firm of Mothes et Dablanc, of Paris. At first only capsules filled
with balsam of copaiva were made, afterwards various nauseating
1' quids, principally oils, were treated in the same way. Soon a
demand for empty capsules arose, and the firm supplied them al o.
The method of making these capsules was described by Mr.
Cottereau in an article in the ‘ Traits de Pharmacologie ’ early in
1835. A small pouch made of a soft skin, shaped like a small
olive, served as a mould. This pouch was fastened by means of a
waxed thread to a small long-necked funnel of metal, the upper wide
opening of which could be closed with a screw cover. Through
this funnel the pouch was filled with mercury in order to expand
it. A solution of gelatin and water was made in the proportion
of 1 part of gelatin to 3 of water, and the expanded
pouch dipped into it. On withdrawing, a rotary motion was
given the instrument until the gelatin had almost hardened ; if
desired, a second or third dipping might be used. The cover of
the funnel was removed and the mercury poured out, by which the
pouch would collapse and could easily be withdrawn. The neck of
the capsule was then cut, leaving a small opening through which it
was filled by means of a syringe. Finally a drop of the gelatin
solution would close the capsule.
In 1838, Mr. Garot, a pharmacist of Paris, read a paper before
the Pharmaceutical Society of Paris ( Journal de Pharmaeie , 1838,
p. 78), in which he states that the manufacturers of capsules having
* Read before the American Pharmaceutical Association, at Montreal.
refused to sell empty ones, he was forced to invent a plan of his
own, in order to fill certain prescriptions of local physicians who did
not wish to have the formula communicated to others. He proceeded
by making a mass of the cubebs and copaiva and other substance?,
and divided and rolled the mass into pills. He then made a
gelatin solution, using one part of gelatin to three of water, put the
pills on needles, dipped them into the liquid, rotated them in the
air until the gelatin was losing its liquid consistency, and kept
them on the ntedle by inserting the blunt end into a thick paste.
After preparing about fifty pills, he would take each needle and
warm it gently at a candle ; the heat beffig sufficient to melt the
gelatin around the needle to allow the latter to be withdrawn. A
warm spatula and a trace of liquid gelatin would finally close the hole
left by the needle. It will be seen that this is substantially the method
used in later years by the manufacturers of gelatin-coated pills,
although other methods are now employed by some. Mr. Garot, there¬
fore was the inventor of the gelatin- coated pill in 1838. Two year
later ( Journal de Pharmaeie, 1840, p. 585) Mr. Vde proposed an
improvement in the coating material by using 1 part of gelatin
7 parts of jujube, and water enough to dissolve both to a syrupy
consistency. This mass would prevent the crackiDg of the coating
caused by the rapid drying and contraction of the gelatin, and also
leave a pleasant flavour in the mouth after swallowing the pill.
Another modification was recommended in 1848 by Mr. M. G.
Jozeau ( Gazette Midicale de Paris, 1848, iii., 193) by substituting
casein for gelatin.
Returning to the capsules, it must be noted that the process
invented and employed by Mr. A. Mothes was a rather complicated
one, and we cannot wonder that ingenious minds looked for
improvements. Such an improvement is recorded in the Journal de
Pharmaeie et de Chimie (vol. 1846, p. 354) by Mr. A. Giraud. He
took small, iron, olive-shaped balls with a wire attached to one end,
and after covering them with a thin coat of sweet almond oil
dipped them into a solution of syrupy consistence of 24 parts of
gelatin, 4 parts of syrup of acacia, 6 parts of simple syrup, and 20
parts of water. The coated moulds were suspended by means of the
wire until the gelatin was cold enough to be touched by the fingers,
when he would grasp each one with the hand and briskly withdraw
the mould. The gelatin mass was elastic enough to expand and
contract agaia. Mr. Giraud finally asked if there would be legal
objections to using this method. The answer is given in a footnote,
stating that this process cannot be used, as it interferes with the
patent of Mr. Mothes. It seems, however, that Mr. Mothes himself
took advantage of this paper, for in 1850, that is, four years later,
we find in the Journal de Pharmaeie et Chimie (vol. 1850, p. 204), a
communication signed H. B., to the effect that Mr. Mothes has
introduced an improvement in making his capsules, in order to over¬
come the variations in size, by taking iron moulds of the shape of
an olive suspended by wires. Then follows the same description
that Mr. Giraud had given before, without giving him the credit of
the invention. We must surmise that French manufacturers, just
like their American brethren, are in the habit of re-inventing, when¬
ever the original inventor is careless enough to publish his inven¬
tion without patenting it at once. From this time the gelatin
capsules were generally used by the French pharmacists and
physicians, and we find many evidences in the various French
pharmaceutical journals. Formu’m for certain mixtures are
recommended, ending generally with the phrase: “Then fill into
gelatin capsules, and close them in the usual way.” It might
be mentioned that in 1878 ( Journal de Pharmaeie et de Chimie ,
1878, ii., p. 74), Mr. Detenhof gives again a description of a method
of making capsules, which differs from Giraud’s method only in the
material. Detenhof used 7 4 gelatin, 14-4 water, and added 14-4
26
PHARMACEUTICAL JOURNAL.
[Jax. 9, 1897
glycerin; he was probably the first one to recommend glycerin in
the gelatin mass.
The French Pharmacopoe’a also took notice of this invention, and
we find an official formula for the manufacture of the gelatin
capsule in the edition of 1866 of the ‘ Codex Medicamentarius.’
The mass employed consisted of gelatin, 30 parts ; gum arable,
30 parts ; sugar, 30 parts ; white honey, 10 parts, and water*
100 parts. The process differs from that of Giraud, in so far that
the olive-shaped iron moulds are not provided with a wire, but are
soldered with their elongated necks to a small plate, so that after
dipping them into the gelatin solution they would stand erect
until sufficiently dry to withdraw them from the mould. The last
edition of the German Pharmacopoeia also recognises the capsules,
and gives a similar formula. Also in other countries the capsules
soon became very popular, and experiments to improve the method
of their manufacture were made by many pharmacists.
In the ‘ Repertorium fur die Pharmacie ’ (1840, xxiv., 2, p. 158),
we find an article on the “ The Formation of the Gelatin Capsule,”
by Adolph Steege, court apothecary at Bucharest. He provided
his moulds with wooden handles fitting snugly into perforations
of a wooden plate. Patting about fifty such moulds into position,
he dips them into the gelatin solution and then rotates
the whole apparatus in the air until the gelatin has become
solid enough to be handled. Taking each handle from the plate,
he cuts the gelatin neck at the proper place, and pulls the capsule
off the mould. This process is substantially still in use to-day,
according to Remington’s ‘ Pharmacy,’ 3rd edition, p. 1231, where
the apparatus used by Parke, Davis, and Co. is illustrated and
described.
In 1845 two pharmacists, Evans and Lescher, invented a process
by which a small animal membrane, made of the small intestines of
the sheep, was used as a covering. A description of their invention
is given in the Pharmaceutical Journal and Transactions , 1845-46,
p. 361.
It must not be forgotten that the capsules so far mentioned were,
without exception, olive-shaped, and had to be closed with a drop
of gelatin solution. They were hand-made, and naturally expen¬
sive. The French manufacturers exported them to all countries,
but it seems that they preferred to sell filled capsules of various
formulte, and while the pharmacists of other countries handled
them, the capsules did not become of general use. To us the ques¬
tion, how they were introduced into American pharmacy, is of
particular interest.
The first mention of gelatin capsules appears in the American
Journal of Pharmacy of 1835, new series, vol. i., p. 351, giving a
short translation of Cottereau’s article in the * Traite de Pharma¬
cologies without any commentary. Only two years later we find
Jn the same journal (Am. Journ. of Ph., 1837, new series, vol. iii.,
p. 20), a lengthy article on “ Capsules of Gelatin,” by Alfred Guillon,
graduate of the Philadelphia College of Pharmacy, which is well
worth copying : —
Provide a suitable number of narrow tin dishes, about 18 or 20 in. in length,
1 in. deep, and about 2 in. in width. In the length of these and in a line, plant
or so’der at a distance of cue inch from each other a number of smoothly formed
metallic knobs of an ovoid shape, whose apex having been somewhat lengthened
out, forms a thin neck by which they are attached to the t'n dishes. This neck
may he about J of an inch in length. Procure a sheet of tin and perforate with
round holes, of which the diameter will be equal to the thickness of the knobs.
Having greased the knobs well with lard, so as not cnly to prevent any adhesion
to them, but also the adhesion of the inner sides of the capsules to each other
after casting, pour melted glue (the most transparent hiving been selected)
upon them and allow it to become tolerably stiff. If you think the shell is too
thin, a second coat may be poured upon the first. The capsule having been
coated, this cast is allowed to cool down to the ordinary consistency of india-
} utter, and having run a knife around the neck, you twist it briskly around and
pull it upwards off the knob. It will immediately collapse and lose the form
1mparted to it on the mou’d, but if laid aside to dry, will by the time it fcas
hardened have regained the desired rotundity. Place it upon your perforated
plate or “filler,” and you can thus convenient'y fill it with the article
prescribed, and close the opening with a piece of gold beater’s s-kin.
It will be noticed that Mr. Guillon used glue instead of gelatin, and
also recommended iron moulds soldered by their necks to small tin
plates, and therefore devised the instrument which is now official in the
French Pharmacopoeia. Asthisarticle was written in 1837, that is nine
years before Mr. Giraud recommended his iron mould with wires,
there is no doubt that Guillon, an American student of the Phila¬
delphia College of Pharmacy, was the first inventor of the improved
process for making capsules, preceding even Steege’s invention by
five years. I have not been able to discover whether any practical
results came from this discovery, the records of the patent office
do not mention any patent for capsules at that time, nor have I
found the inventor’s name anywhere later.
The real capsule industry in America dates from 1836, when Mr.
H. Planten emigrated from Paris and established a capsule business
at No. 3, Chambers Street, New York, at the place where the East
River Savings Institution is now located. Filled capsules, accord¬
ing to French formulae, were manufactured after the process of
Mothes, and new ones added whenever a demand arose. The cap¬
sules were first sold as “ Mothes’ capsules,” and the labels printed
in French and English. Powders were also put in the capsules, if
ordered. Capsules in two parts were also made, the lower part
filled and then capped. But their manufacture was soon abandoned
as unpractical, the two parts rarely fitting well. The firm of H.
Planten, now H. Planten and Son, never patented any machinery,
and invariably decline to announce their methods. How long they
adhered to Mothes’ original process, or when improvements were
made is therefore impossible to say. The old firm of B. Keith and
Co.’s also attempted to introduce empty gelatin capsules and manu¬
factured them here about 1860, but soon abandoned the attempt.
E. Fougera and Co., of New York, also imported French capsules for
many years, but during the last twenty years the domestic capsules,
on account of their cheapness, superseded those imported.
In 1863 the firm of H. Planten took up the industry of empty
capsules for powders and liquids. The first capsules intended for
powders alone were called by them Jujube Paste capsules and were
offered to the trade before 1870. Another manufacturer, Dundas
Dick, also experimented in the same direction and secured a patent
on cone-shaped capsules as early as 1865. The first inventor, how¬
ever, to manufacture capsules, as now used, by machinery, to
devise ingenious apparatus for their production on an extensive
scale and to render their use popular in pharmacy, was Mr. F. A.
Hubei, of Detroit. He secured his first patent for a capsule
machine February 13, 1877, although he had already manufactured
and sold empty capsules as early as January, 1875 (see Parke, Davis,
and Co.’s price-list of 1875). From this date till 1883 we find a long
list of patents in the records of the patent-office, some of them
granted to Mr. Hubei, some to other inventors. Disputes as to
priority soon arose, and law suits followed, in which Mr. Hubei was
victorious. His whole output is brought into the market by Parke,
Davis, and Co. The following is the process employed by him,
which I copy verbatim from a letter that Parke, Davis, and Co. had
the kindness of sending me in answer to my inquiry :
“ Metal moulds set in metal plates are first lubricated, and then
dipped into solution of gelatin. They are withdrawn at a regulated
speed, the solution being of a given temperature, and that tempera¬
ture being higher according as the temperature of the mould is
lower and vice versd. The temperature of the moulds, and of the
solution and the speed at which the moulds are withdrawn, deter¬
mine the thickness of the capsule. The solution comprises seven
Jan. 9, 1897.]
PHARMACEUTICAL JOURNAL.
2 7
puts of water to four of gelatin. After dipping, the gelatin
investment is allowed to congeal sufficiently, and it is then cut by
a special cutting machine, and the waste aborft the cut is shoved
away from the capsule. The capsules are dried by passing a current
of air over them, and when dry and hard are stripped from the
mould by machine. The caps are joined to the bodies by hand, and
at the same time defective capsules are sorted out and rejected.
The finest quality of gelatin is alone suitable. The one other
process we are familiar with varies from the foregoing only in the
fact that after dipping the moulds, the capsules are allowed to dry
wholly, or almost wholly, before stripping.”
I also quote from a letter of “ The Merz Capsule Co.,” of Detroit,
who write : “ In order to make capsules properly and sufficiently
cheap it requires a large amount of complicated and expensive
machinery, and constant attention to small details, inasmuch as the
one-thousandth of an inch difference, more or less, in the thickness
of a capsule will either make it a loose- joining or a tight- joining
capsule.
The last invention on the field of capsules is that of Mr. Heine-
man, who now manufactures empty elastic capsules for fluids.
“ By means of these the druggist is enabled himself to fill elastic
capsules as occasion may require, perfectly and without loss of
time, doing the work as well as the capsule manufacturer himself
could do the same in the factory. The convenient shells will keep
almost indefinitely, are always ready for use, and enable the
druggist not alone to avoid carrying a large stock of filled capsules,
but enable him to dispense freshly made capsules containing an
almost indefinite variety of formulae wilh whatever variations
physicians may be pleased to give them from time to time, as the
needs of the patient may require.”
The use of the gelatin capsule is daily extending, not only in
medicinal and pharmaceutical adaptation, but also for mechanical
purposes of varied kinds. They are employed for beef juices and
ether extracts, for candies and chocolates, for inks and blueing.
The latest use to which they are put is for packing cigars, in order
to better preserve the flavour, and daily new ideas appear in which
the gelatin capsule may take part in due time.
( To be continued. )
THE CHEMICAL LABORATORY IN PHARMACY.
BY JOS. L. MAYEE, PH.G.
Not unfrequently one hears some cynical druggist laugh and
sneer when something is said about the present courses of instruc¬
tion in a college of pharmacy. The name cynic is perhaps better
suited to druggists of this class than any other, for, according to
Henry Ward Beecher, a cynic is a person who never sees a good
quality, and never fails to find seme insignificant bad one. The
cynical druggist never sees the many advantages of a college of
pharmacy, but never fails to find and point out some disadvantages
which oftentimes exist to him only.
The disadvantages which he will almost invariably point are — the
cost of a college course as compared with the expense of passing a
board of pharmacy, the idea that there is not enough practical
pharmacy taught, never forgetting to say some sarcastic or ironical
things about the chemical laboratory requirements ; in fact, he is so
biased and prejudiced that he will hardly admit one advantage of
the college of pharmacy course as now mapped out.
This class of persons claim that to-day, when pharmacy is down
about as low as it can ever come (speaking from both a financial
and professional standpoint), the colleges seek to teach the embryo
pharmacist “ these scientific studies” (as they are pleased to allude
to them), which were never required in the time when pharmacy
was yet a profession, and there was money making on all sides
They say that those times were prosperous ones for the druggist,
notwithstanding the fact that the average druggist had no pharma¬
ceutical college education. The money-making question is about as
far as they go, and here they stop. They do not mention the fact
that at that money-making period the undermining of pharmacy as
a profession wa3 going on, until at last the climax was reached, and
there was neither professional nor financial advancement. The
competition was so sharp on all sides that the druggist and his
profession, instead of keeping pace with the advancing professions,
kept at a standstill. All this time these ever-complaining druggists-
were idle, never lending a shoulder to the wheel to help out of the
mire the fallen profession. They were the Neros of their time ;
while the profession was sinking, they were money-hunting.
It was at this juncture that the colleges of pharmacy took an
active part, and with the aid of the pharmaceutical press laid a new
foundation for the new resurrected profession. This foundation
was so laid that the pharmacist could consistently be a professional
man and at the same time make money. While medicine has pro¬
gressed so rapidly and attained such a high position, physicians
have not suffered financially thereby.
The colleges which have built up the new profession to its present
standard, and know not such words as “good enough,” are to-day
graduating men yearly who are better fitted to perform the duties
of a pharmacist than any class of men ever were before ; they are
not turning them out too full of theory to make good practical
pharmacists as some would have us believe.
There is hardly a college to day but makes it obligatory on a
student who wishes the degree of Ph.G. to take the courses in.
chemical analysis, the more important ones requiring quantitative
as well as qualitative analyses. The cynical druggist, when he
yearly opens the various college announcements sent him, notices
this part of the instruction, and begins to jest, claiming to be un¬
able to understand why all this is required of the present pharma¬
cist, as he will never have the time nor occasion to make any
analyses ; for the wholesale houses are so reliable that there is no
necessity for a druggist to make an analysis of the drugs he receives.
The Pharmacopoeia Committee never thought that way (and they
are credited with knowing some of the needs of the practical phar¬
macist), or else they should never have given all the standard
strengths of purity and a method of estimating them volumetrically
or gravimetrically, as in the case of the preparations of opium.
They recognised the fact that the druggist of the day must have a
genuine right to hang out his sign “Druggist and Chemist” ; that
the druggist of the day must make money in some other way than
making the professional interests suffer, and that the druggist can
better prosper as a professional man than he can as a mere tradesman.
There is perhaps to-day too much reliance placed on the various,
wholesale houses from whom the druggist buys his drugs and
chemicals ; there are too many druggists who dismiss the query,
“ Do you ever analyse your drugs or chemicals to see whether
they comply with the Pharmacopoeia requirements 1 ” with a mere
“No, the wholesale houses I buy from are very reliable.”
The institution with which the writer is connected had several
experiences in buying from these “reliable wholesale houses”
lately, which will not be out of place to cite here. For the
determination of starch quantitatively according to a method here
employed, among other reagents required is barium hydroxide,
which must, like all chemical reagents, be absolutely pure — in fact,
so much so, that it is a custom to test all the chemicals before
proceeding to make any of the tests in the laboratory. In procuring
this we did not depart from the custom, and subjected it to the
usual tests, finding very little barium hydroxide, but chiefly
28
' PHARMACEUTICAL JOURNAL.
[Jan. 9, 1897
carbonate. It is not to be supposed that we looked upon this as an
adulteration on the part of the manufacturer, as the Ohio Food
Commission has recently been doirg ; but, instead, knowing the
rapidity with which the one salt is conveyed into the other, we
looked upon it as the result of carelessness on the part of the
wholesale house.
On another occasion on ordering some sodium bromate to be used
in a modification of the U.S.P. process for estimating phenol, our
analysis showed but 10 per cent, of bromate of sodium, and 90 per
cent, of bromide of sodium. This, like the former salt, was also
obtained from a reliable dealer. Several more cases might be cited
that came to our notice, but these will suffice as an illustration.
When a college of pharmacy receives chemicals marked c. p., and
upon analysis finds .they are not as represented, what then is the
druggist to do to protect himself 7 He must be competent to do
just what the laboratory assistant does before the day’s work is
begun — he must establish a little laboratory and test his various
chemicals as he receives them.
This accounts for the fact that to the laboratory courses is yearly
added more time ; it accounts for the Pharmacopoeia devoting so
much space to tests and test solutions. While these two manufac¬
turers were responsible people, it does not follow that all vendors of
drugs deserve the same title.
Of course, anyone who had been taught analysis at a college
could oftentimes take advantage of a special price by making an
analysis before buying. Then the various courses in analytical
chemistry embrace a course in urine analysis, both qualitative and
quantitative, and some colleges teach microscopical methods. The
student is taught the best methods for such analysis, so that when
he leaves college he may be another to help heal the breach and
lower the friction now existing between some pharmacists and
physicians. It is a great relief to a physician to know that he can
take his samples for examination to a pharmacist who has had the
necessary training to fit him for this work ; the physician appre¬
ciates the favour, and the druggist is not forgotten for it.
Some of the laboratory courses also embrace instruction in the
analysis of foods, such as milk, water, etc. At this day, when there
is such an encroachment on the rights of the pharmacist by the
dry goods stores, he can find an avenue to escape from their methods
by taking to chemical analysis ; thus he could make an occasional
dollar, not to say anything of the many friends he would thereby
gain.
The claim that is sometimes urged against the establishment of a
chemical laboratory in the rear of the store or any other suitable
place is the expense. This need be no serious item, for it is not
necessary to have chemical reagent bottles j for, as a matter of
fact, any clean glass-stoppered bottle will do, and the reagents are
quickly and cheaply prepared, the pharmacist having most of the
chemicals in stock. A second objection urged is the time required
to make an analysis. This should not be considered, for any of the
U.S.P. methods, with a few exceptions, can be carried out in a few
minutes ; and it also requires but a few minutes to complete a urine
analysis.
Another great advantage of a course in chemical analysis is that
the student is taught accuracy ; accuracy in putting up preemp¬
tions as well as analysis, for the analytical chemist knows no such
word as “ about.” Training of this kind is what makes the man
who has taken the course superior over his fellow-druggists who
have not done so. The importance of accuracy, which is impressed
on a man when he is at college, is never forgotten, no matter how
long he may stay in the drug business.
Ic is but recently that we sent out prescriptions to a number of
pharmr cl -ts for various amounts of drugs, and upon measuring or
weighing them found some short of the amount prescribed. These
were probably put up by men who were never taught to be accurate,
for this is a principle very rarely found in a man behind a drug
counter, unless, as before stated, he had had the laboratory training.
By the combined efforts of the pharmaceutical colleges and phar¬
maceutical press, the day is not far distant when behind every drug
store will be found an analytical chemical laboratory. — Druggists'
Circular.
THE TBEATMENT OF GOUT.*
In this work the author, if he adds little to the subject, discusses
gout from its many different aspects, both theoretical and
practical, and this in a way that allows of what is at present known
and what surmised beiDg readily followed.
The great advance made by Sir Alfred Garrod (viz, the demon¬
stration of an excess of urates in the blood before and during an
attack) is justly dwelt upon ; even now nothing of corresponding
importance has been added to our knowledge of the subject. The
large number of theories held as to the nature and
causation of gout shows, as the author observes, how
much yet remains to be discovered. By the term “goutiness” he
himself understands what is otherwise known as latent gout, the
functional disturbances of a general kind recognised only by
clinical symptoms, as distinguished from the local lesions like
those met in the joints. The pathognomonic lesion of local gout
is the deposition of urate of soda in the tissues. In “ goutiness ”
this is absent, yet the term is justified by the adoption of such
criteria as the disappearance of these symptoms under treatment
that is successful in gout, or after the occurrence of an articular
outbreak. Such “goutiness” is witnessed in inflammations
of the larynx, bronchi, stomach, liver, heart, veins, skin,
etc. An extensive review of the theories held upon
the nature of gout would be of little purpose ; briefly, it may be
enough to state the following : — Garrod holds gout to consist in
the group of changes and symptoms connected with the deposition
of urate of sodium in the joints and tissues ; there is an accumula¬
tion of the urate in the blood in consequence of a defective
excretion by the kidney, which in the first place is functional, and
may be an inherited or acquired defect. Ebstein, after pointing
out the death of tissue or necrosis that is met with in gouty foci
(which has been more fully studied in this country by Berkart),
formulates the view that this is to be explained by the local action
of urates on the tissues, the crystallisation of the urate oc¬
curring subsequently in the necrosed foci by reason of the acidity
of the latter. The alleged poisonous property of solutions of urates
upon the tissues has not been confirmed, however, by their experi¬
mental injection in animals. Berkart is inclined to view the tissue
degeneration as the essential antecedent factor in gout, the deposi¬
tion of uric acid being an epiphenomenon, and not the essential
part of the disease.
Ha;g’s theory assumes that uric acid in the soluble form in which
it circulates in the blood is poisonous or toxic, and may produce
various clinical results. The experimental injection of large quan¬
tities of urates into the veins of animals, however, has not been
productive of any results.
A considerable modification in the theories of gout has arisen out
of the investigations of Horbaczewski, who showed that uric acid
might be derived from tha decomposition of the tissues themselves,
particularly f i om the spleen, and that it was furnished by changes
* ‘ Gout and Goutiness and their Treatment.’ By William Ewart, M.D.
Cantab., F.R.C.P. Lond., M.R.C.S. Eng., Physic’an to St. George’s
Hospital, London. Pp. 589. Price 12s. 6 d. London, Balliere, Tindall
and Cox. 1896.
Jan. 9, 189 7 J
PHARMACEUTICAL JOURNAL.
29
taking place in the nuclein of the cells, especially the leucccytes,
so abundant in the spleen.
The influence of the nervous system has been maintained by Dr.
Ord, and more lately by Sir Dyce Duckworth, the latter holdirg
that some nervous disturbance is responsible for a peculiar incapa¬
city for normal elaboration of focd within the whole body, whereby
uric acid is formed at times in excess, or is incapable of being duly
transformed into more soluble and less noxious products. Coosi 'erable
space is devoted to the consideration of Sir William Robert’s view,
which holds that the deposition of urate is brought about by excess of
sodium salts, and that the localisation of the deposits is due to
the amount of soda or richness of the part in soda salts ;
amongst the fluids of the body synovia has the highest per¬
centage of sodium, and Sir William Roberts supposes that t e
deposition in the joints proceeds from this. What will be of more
interest to readers of the Journal are those portions of the
work treating of the therapeutical and especially the medicinal
agents used in the treatment of the dise se. The indi¬
cations for the use of emetics, purgatives, diure'ics, and
diaphoretics being disposed of, there follow two chapters
devoted to a discussion on the value or colchicum. It
is noteworthy that the use of this specific may be traced
back to about the year 580 a d., when it was intro¬
duced under the name “ Hermodactyl ” by Alexander
of Tralles. Hermodactyl was freely employed in the
Middle Ages by the Arabian physicians Avicenna and
Serapion.
Its remarkable specific properties in alleviating the disease
admit of no scepticism in the mind of Dr. Ewart ; indeed, the only
questions for discussion are the injurious results arising from its
excessive use, and its contra indications. Yet the mode of its
action is so subtle that as yet it has defied analysis. It is instruc¬
tive to observe that the author supposes the specific action of
colchicum to reside in the happy comb’nation of its cholagogue,
purgative, nerve-depressing, and heart- depres sing properties. Should
this be so, it indicates the theoretical value of combination in pre¬
scriptions other than those for the alleviation of gout, and suggests
further that simplicity in prescribing may be carried so far as to
defeat its own ends.
Beddes such treatment, that by meins of alkalies (the salts of
sod um, potassium, lithium) is discussed, as well as that by
salicylic acid and its compound0, and by other agents of less
importance, whilst the bock closes with a notice of medicinal
springs, heme and continental, and the dietetics and general
Iqgieie indicated in the prevention and treatment of the
disease. Under the choice of alcohol, more particularly, the author
states definitely that in acute gout alcohol is contra-indicated ; and
that in chronic gout its chief value i3 dietetic. Comparative
safety lies in avoiding all wines and malt liquors, and in trusting
to that form of spirit which most approaches pure alcohol; tho
best whiskey, well watered, is therefore to be preferred to all else.
Ale and stout, and of wines, champagne beyond all, are strictly
forbidden.
Phenacetine in Ttphoid. — Hiving treated over 200 cases of
typhoid with phenacetine during the past four years, and only
having had six deaths, B'gnami ( Gaz . d'Oup) naturally concludes
that the remedy is a very valuable one in this disease. The drug
is given at once as soon as the disease is diagnosed or merely sus¬
pected, in doses of 3 grammes in twenty four hours, divided into
six do re5, in cachetp, one being taken every four hours. Infants and
old people are given from 1| to 2^ grammes in the same period. —
B.M.J. Epit , 2/96/92.
LITERARY_NOTES.
‘ Bacteriological Diagnosis,’ by St. George Reid, is a useful
collection of notes, intended as an analytical key to the subject the
name of which serves the book as a title. Originally drawn up
for use in differentiating mouth and throat organisms, the scope of
the tables has been extended so as to embrace most of the known
bacteria. The works of Crookshank, Fliigge, Schenk, Sims
Woodhead, and Sternberg have been freely drawn upon, but bac¬
teriological technique is advisedly left for treatment elsewhere.
The first table includes micrococci which liquefy gelatin, these
being divided into species which form white, red, or yellow
colonies, and those again subdivided according as the cocci occur
in chains, masses, etc. The next table deals similarly with micro¬
cocci that do not liquefy gelatin, the third and fourth with
bacilli, and so on. Finally there are classified lists of the
organisms found in air or water, in the nose and mouth, those
known to form spores, and others whose growth is accompanied by
a foul odour. The scheme of bacteriological analysis thus con¬
stituted is ingenious, and should prove of considerable value to
everyone concerned with the treatment of diseases with which
specific micro-organisms are associated, and the detection of the
latter. The book is published at 2s. 6 d., by BaillUre, Tindall
and Cox, London.
Wall Calendars for 1897 are published by Messrs. Evans,
Gadd, and Co. , of Exeter, and Messrs. Parke, Davis, and Co. ,
London.- Both are arranged on the excellent plan according to
which all the dates for a given month appear on the same sheet,
and this can be torn off to expose that for the next month. Messrs.
Evans, Gadd, and Co.’s card also shows a calendar for the whole
year, such as is found useful in referring to a date during a past
month, whilst the production of the London firm is ornamented
with a finely printed engraving, the subject of the picture being
an invalid cat with its jaws bound up and medicine bottled along¬
side its couch. The patient is represented as plaintively murmur¬
ing “ And yet — they call this fun ! ”
Ham’s ‘Inland Revenue Year-Book,’ edited by E. Grant
Hooper, F.I.C., F.C.S. , and others, is now in its twenty-first year,
and may be specially commended to the public and to readers of
the Journal in particular, for the simple and non-technical informa¬
tion which it furnishes in connection with income tax, the
death duties and the mode of obtaining probate of wills,
the origin and extent of the contribution from Imperial sources to
the local taxation account, the annual Exchequer state¬
ment, the statistics illustrating the progress and trade
,of the nation, the political information dealing with
the successive Governments of the Queen, and those who have
filled the more important political offices during the nine¬
teenth century, and lastly the recent additions to the
peerage. It includes a diary, the fullest information (with
statutory authorities, etc. ) for the numerous licences and
duties placed under the control of the great Inland Revenue
Department, not excepting even the latest and scarcely
fully-fledged arrival, the light locomotive. To chemists
who compound or sell proprietary medicines, and all others
closely affected by revenue law this well-known annual is
indispensable. Statistics illustrating the progress of the nation
constitute a wonderfully compendious statement as to population,
revenue, trade, railways, letters, savings, education, pauperism,
etc., presenting not the slightest intricacy. The work is pub¬
lished by Effingham Wilson and Co., 11, Royal Exchange,
London, E.C., at 3s. or, with Warehousing Regulations at 4s. 6 d.
30
PHARMACEUTICAL JOURNAL.
[Jan. 9, 1857.
THE STUDENTS’ PAGE.
WHAT THE MICROSCOPE DOES.
The pharmacist of to-day finds considerable use for the microscope;
the pharmacist of to-morrow will find it an indispensable accessory
in his business. Already a limited knowledge of the use of the
instrument is required in the examination room, and as time
passes the requirements in this direction are likely to be greatly
extended. Accordingly, it seems desirable to point out that
the microscopical examination of substances is simply an
essential step in the complete visual examination of those sub¬
stances. Everyone realises that the nearer, within certain
limits, an object is brought to the normal eye, the larger it appears
and the more distinctly its details are apparent. When brought
within a distance of two or three inches, however, the image
becomes blurred and indistinct, whilst an object held close to the
eye cannot be seen at all, and simply obstructs light. Now
the use of a hand-lens enables one to bring an object under
examination much closer to the eye than is normally possible, for
the outer surface of the lens represents that of the eye for the time
being. As a result the object appears much larger, and more
structural detail is revealed than when the object is viewed by the
unassisted eye. Similarly, the compound microscope still further
lessens the distance between the object and the eye, the surface
of which is now represented by the front of the objective, and to
speak of the image of an object as being enormously magnified
under the microscope is simply another way of expressing
the fact that the object has virtually been brought into such
close proximity to the organ of sight as is normally impossible.
Examination of an object by the aid of the microscope, therefore,
must be regarded as a mere extension of the limits within which
the normal human eye is capable of clearly distinguishing the
details of objects. As spectacles help the partially blind to see, so
the microscope enables those with perfect eyes to see more than is
possible without such aid, and the natural conclusion is that phar¬
macists and others whose skill is partly dependent upon the
accurate impressions they form of the appearance of objects,
should be adepts in the use of an instrument that can so increase
their natural powers.
THE STUDY OF PHARMACOGRAPHY.
The study of materia medica is, fortunately, so independent of
weather and season that it may, without disadvantage, be pur¬
sued at the present moment. The student will derive the greatest
benefit from exercising himself in the accurate description of drugs,
for such exercise compels him to observe closely and minutely, and
it is just in the power of accurate observation that the student is
usually deficient. He should never be satisfied until he is able to
record his observations concisely v nd accurately in writing, for
“ writing rnaketh an exact man.” The easiest plan to follow is to
divide the drugs into morphological groups and deal with the
leaves first. Now, it may seem a comparatively easy task to describe
a leaf, but in reality certain difficulties will be encountered. Never¬
theless, with a little practice the principal characters of any leaf can
soon be grasped and clearly and briefly transferred to paper. Note
should be taken of the following points : — Size, colour, texture,
outline, margin, apex, base, petiole, venation, surface, odour, taste.
Every specimen must be examined in each of these respects, and
the result of the examination systematically recorded.
Size. — A leaf will naturally increase in size until it arrives at
maturity. Length and breadth of the smallest and largest should
be noted, as well as of the size that is most frequent in the specimen
under examination.
Colour. — The colour of a leaf may be sufficiently accurately
described by the terms in common use, such as “ dark green,”
“brownish-green,” etc. Both upper and lower surfaces must be
examined.
Texture, outline, form, margin, apex, base. — For an enumeration
of the differences that leaves exhibit in these respects, reference
must be made to one of the standard descriptive botanical works,
such as Asa Gray’s ‘ Structural Botany’ (1879). The illustrations
should be transferred to the note-book and the proper designation
appended. In this way a convenient standard is provided to which
the leaves can be referred when they are being examined. Such a
standard having once been adopted should be adhered to.
Venation. — The texture, outline, form, margin, apex, and base
having been ascertained and noted, the next course for the student
is to examine the venation of the leaf. This is an important charac¬
ter. The outline of the leaf should be sketched in the note-book,
whilst the midrib and direction and course of the principal lateral
veins should be indicated. The nature of these veins should also
be carefully noted. They may be scarcely visible or they may be
distinct ; in which case they may be prominent or depressed.
Surface. — This examination of the veins will naturally lead to a
close scrutiny of the surface of the leaf, both with and without
the aid of a lens. The presence or absence of hairs and glands
must be ascertained ; if present, their particular characters must
be noted. They may be present on one surface or on both surfaces
of the leaf, and on the veins alone, or on the interneural spaces
as well ; they may be found in young leaves, but may fall off as
the leaves attain maturity. During this examination the leaves
should be scrutinised by transmitted light. Pellucid dots are
frequently (but not always) caused by the presence of oil glands,
a fact which should be fully recorded.
Odour and Taste. — No examination or description is complete
without specifying the odour and taste the leaf possesses ; these
are frequently so characteristic as to be of material service in
identifying a leaf. The odour can best be appreciated by crushing
a leaf and smelling it, or from leaves in bulk.
NOTES ON THE BOTANY OF JANUARY.
Poinsettia is a somewhat difficult flower to examine, but if
the student will refer to former pages of this Journal [3], vol. viii.,
p. 501, he will have no difficulty in understanding its structure.
That of Helleborus niger is explained in Ph. J. [3], vii. , p. 610.
Holly.— The “berries” are not, strictly speaking, berries, since
like the buckthorn they contain stones or endocarps. The fruit
might be termed baccate (or baccoid). It is superior, and con¬
tains four triangular endocarps, which are curiously reticulated
with raised veins or ridges. The minute calyx and the nearly
sessile stigma are not easily recognised. The plant is an ever¬
green shrub (several stems), or sometimes has only a single large
trunk, and forms a tree. The leaves are commonly said to be
prickly, but it would be more correct to call them spinous, since
their character is due to the hardening of the edge of the leaves,
more particularly at the apex of the lateral nerves or veins. The
upper part of the plant, and even the terminal leaves, are often
devoid of spines, a feature which seems to depend on a temporary
or local abundance of moisture, since a prickly and an unarmed
leaf may often be found contiguous to each other. The leaves are
coriaceous in texture, and have a shining surface.
Mistletoe. — The fruit differs in structure, the calyx being
adherent to the ovary, and the walls of the ovary are so developed
as to form a viscid pulp, which fills the cavity present in ordinary
ovaries. The seeds also are remarkable for often containing two
embryos. The cotyledons, as well as the albumen, are dark
green, containing chlorophyll, and the pulp of the less fruit contains
some constituent that prevents it from drying for a considerable
time when exposed to the air. An interesting account of the
germination of the seeds is given in Kerner and Oliver’s ‘ Natural
History of Plants,’ i., pp. 205-209. The seeds at this time of the
year are not usually mature, but planted in March they will easily
germinate in a crack or slit made in the young bark of the black
and Lombardy poplars.
Ivy. — The berries of the ivy contain five seeds, and the ovary
is inferior, the five minute calyx teeth crowning the fruit. This
plant serves to illustrate the difference between the Araliacece. to
which it belongs, and the closely allied natural order Umbelliferce.
In the Araliacece there are always more than two seeds, and the
double epigynous disk of the umbelliferous plants is absent.
HINTS ON FIELD BOTANY.
The young student may easily be deterred from the practical
study of systematic botany by too early an introduction to a Flora.
A much better plan is to begin with a copy of Shirley Hibberd’s
‘ Field Flowers,’ and after collecting all the specimens available,
sit down and identify them by the aid of the letterpress descrip¬
tions and coloured plates in that book. Grierson’s ‘ Lessons from
Fields and Lanes ’ may also be usefully referred to, the flowers
obtainable each month being treated in separate chapters as in Shir¬
ley Hibberd’s work. The next step should be to write out full de¬
scriptions of as many of the specimens as possible. Here Holmes’
‘ Botanical Note Book ’ will be found of the greatest value. Finally,
compare the written descriptions with those in Hayward’s
‘ Botanist’s Pocket Book,’ or some other good Flora. Before
beginning field work a second year carefully run over the de¬
scriptions of all specimens collected the previous season.
PHARMACEUTICAL JOURNAL.
31
JAN. 9, 1897]
Pharmaceutical Journal.
A Weekly Record of Pharmacy and Allied Sciences.
ESTABLISHED 1841.
Circulating in the United Kingdom, France, Germany,
Austria, Italy, Russia, Switzerland, Canada, the
United States, South America, India,
Australasia, South Africa, etc.
Editorial Office : 17, BLOOMSBURY SQUARE, W.C.
■Publishing aqd Advertising Office : 5, SERLE STREET, W.C.
LONDON : SATURDAY, JANUARY 9, 1897.
THE PROTECTION OF TRADE INTERESTS.
Some nine years ago an article appeared in these columns
■entitled “ The Philosophy of ‘ Cutting.’ ” This aroused con¬
siderable antagonism on the part of some leading pharmacists,
who thought the “cut-rate problem ” was a subject that should
be strictly tabooed. Nevertheless the cutting difficulty has
increased and compelled recognition on every hand, until at
last an association has been formed which has for its sole
ultimate object the regulation of prices in a certain section of
the chemist and druggist’s business. In the article referred
to (see Ph. J. [3], xviii., 827), an attempt was made to show
that a tendency exists to gradually reduce the prices
of all commodities to the point at which a fair
rate of profit shall be realised. The process is slower
in some cases than in others, and it occasionally
happens that prices are reduced to an extravagantly low
point. But this is simply a natural result of maintaining
prices for a time at an unduly extreme limit in the opposite
direction. A moving pendulum does not stop directly it
arrives at zero but passes to the other side, and only gradually
comes to rest. Similarly the reaction following an inflation
-of prices tends to reduce those prices below the point at
which a fair profit can be realised, but a reaction in the
■opposite direction may be expected to follow sooner or later,
and a certain fluctuation will then be apparent f<?r some time
longer, even though no other factors, such as diminished
cost of production, etc., should come into play. Of course,
the matter is here considered from the strictly trading
point of view, but in this connection it may be useful
to quote from “ The Philosophy of ‘ Cutting ’ ” the follow¬
ing passage : — “ It ought to be unnecessary to remind phar¬
macists that, in so far as they are tradesmen, they must expect
no advantage over other tradesmen . As professional
men they may look for more, and in fact are entitled to
much more ; but this also must be worked for . The
real source of profit in pharmacy is the skill attained, and
in proportion . as this is exerted and produces satisfactory
results, just so much must the faithful pharmacist expect
to he repaid for, in addition to mere commercial profits.”
This quotation seems fairly to represent the point of view
from which the present agitation in favour of regulating
the prices of proprietary articles ought to be regarded by
chemists and druggists.
In the present issue of the Journal (p. 23) the case for
the Proprietary Articles Trade Association is stated by the
chief promoter and secretary of that body. His statement
is a very fair one, and after perusing it our readers ought
to have no further cause for misapprehension as to the
objects of the Association and its methods of attaining
those objects. It is not proposed to comment on what Mr.
Glyn- Jones says, for the subject is one to be discussed
by the parties chiefly interested — privately rather than in
public, informally rather than in set debates. Privately,
because it never pays to let your opponents know on
what lines you propose to attack them ; informally, since
thus only can you expect the greater proportion of the craft
to take part in the attempt to arrive at a useful result.
Everyone ought to form a definite opinion on a matter so
vitally concerning the interests of all, and this can best be
brought about by quiet chats amongst those called upon to
decide. Meetings in different centres may doubtless serve a
useful purpose, and especially in proportion as they are
small and private, but more good can be accomplished by
local secretaries and other prominent pharmacists calling
upon as many of their fellows as possible to talk the matter
over. If then reports were forthcoming from each district,
a consensus of opinion would readily be arrived at, and this
of such a nature that it might safely be acted upon. A
virtual federation would thus be formed, including the whole
of the fifteen thousand registered chemists and druggists,
and there would be no difficulty in the way of determining
within narrow limits exactly how many took one side on the
question at issue and how many the other.
Assuming, for the sake of argument, that the whole or a
vast majority favoured the views of the Proprietary Articles
Trade Association, how much more effective would be the
force placed within the control of the leaders of the move¬
ment than anything now available 1 Manufacturers and
wholesale dealers would be compelled to fall into line
without further consideration, and the movement would
be overwhelmingly successful, merely because of its com¬
pleteness. Suppose, however, on the other hand, that only a
small minority approved of the policy of uniting to
maintain prices at a point where a fair profit will be
yielded, it would manifestly be unwise to proceed further in
the matter for the time being. In either case, the result would
be practically conclusive, whilst in the event of an adverse
decision it would be possible to decide whether it was worth
while attempting to educate opinion in the matter, and if
so, in what direction 1 But only by practical unanimity,
such as is advocated by Messrs. Barrett and Foul-
ston in this number of the Journal, can any per¬
manent effect be produced, and even then the effect
will be limited to the maintenance of a fair and reasonable
profit. It must not be forgotten that the public has a voice
in the matter, and that the popular vote will invariably be
cast in favour of the minimum price, other things being equal.
Manufacturers, too, cannot be depended upon to trouble
themselves much about the rate of profit reaped by distribu¬
tors. Their only anxiety is to get their goods into the hands
of the public, and they consider it of little importance
whether this is done by the chemist or anyone else so long as
business is done. In the end, therefore, the retailer must
rely upon himself, and act upon his own initiative. If,
however, he acts alone, he can effect but little, whilst if he
proceeds in accordance with a plan previously agreed upon
by the majority of those similarly situated, benefit cannot
fail to ensue.
32
PHARMACEUTICAL journal.
[Jan 9, 18f 7
ANNOTATIONS.
The List of New Year Honours, published last week, is
chiefly remarkable for the announcement of a unique distinction
for a medical man, a peerage of the United Kingdom having been
conferred upon Sir Joseph Lister, Bart. But it would perhaps be
more accurate to attribute this event to the distinguished surgeon’s
position in the world of science, rather than in that of medicine,
for his discovery of the antiseptic system in surgery was a
scientific discovery of the first order, and the recognition his services
to humanity have received have been fully merited. Already he
enjoys the rare distinction of being at one and the same time
President of the Royal Society and President of the British
Association, and the action of the Queen in conferring the peerage
but serves as an official expression of the country’s approval of the
results of a noble life-work. Another medical man, Dr. Richard
Douglas Powell, of Wimpole Street, who is an authority on chest
affections, receives a baronetcy.
Science is Truly in Luck, for after occupying the position of
Cinderella, the household drudge, during untold years, she is now
being fully recognised by the fairy godmother, who manifests,
her existence by sending down showers of gold. Quite
recently we had occasion to speak of Dr. Ludwig Mond’s mag¬
nificent endowment of research, and this week it is announced that
the late Dr. Alfred Nobel has bequeathed a sum, estimated at
nearly two million pounds, for the advancement of science. The
yearly interest of this sum is to be divided into five equal portions,
three of which are to constitute prizes for the most important
discoveries in physics, chemistry, and physiology or medicine,
whilst a fourth is to reward the most distinguished literary,
contribution in those departments of science, and the fifth is to be
awarded to that individual who shall have done most to promote
the cause of peace. Competition for these prizes will not be
restricted by any conditions as to nationality.
The Pasteur Institute, Paris, is also to benefit, it is reported,
by a donation of eighty thousand pounds from Baroness de Hirsch.
Thi3 money will probably be partly used for fully equipping a
laboratory of biological chemistry, in which the successors of
Pasteur will be enabled to conduct extended researches in connec¬
tion with the products of the activity of minute organisms. This
addition to the pecuniary resources of the Institute will come at a
time when it is calculated to confer great benefit, for the funds at
present available do not suffice to defray all incidental expenses.
The Davy Faraday Research Laboratory of the Royal
Institution is to be opened for work on Monday, January 18, and
applications are invited from would-be investigators in pure and
physical chemistry. As has already been explained in these pages,
workers in the Laboratory are entitled, under the Deed of Trust,
to free supplies of gas, electricity, and water, as far as available,
and, at the discretion of the Directors, to the use of the apparatus
belonging to the Laboratory, together with such materials and
chemicals as may be authorised. It is now announced that all
persons desiring to be admitted as workers must send evidence of
scientific training, qualification, and previous experience in
“ original” research, along with a statement of the nature of the
investigation they propose to undertake. Further information,
together with forms of application, can be had from the Assistant
Secretary, Royal Institution. Perhaps among other information
may be forthcoming the long-desired definition of “original”
research and of its suggested “second-hand” correlative. Or
will some brave investigator undertake, as a forlorn hope, to
ascertain exactly ivhat the word “original” means in this
connection ? Can it imply research made in Germany and uttered as-
of native growth ?
The Nature of Light was made as clear last week, at the Royal
Institution, as it is possible for anything to be which is based on a
hypothesis incapable of proof. In the first place, the wave theory
was explained by Professor Silvan us Thompson, whose practical
demonstrations are such as appeal to the most unscientific minds,
then the convergence and divergence of light waves were illus¬
trated, as well as the action of the photometer, the principle of
the kaleidoscope, and other kindred matters. The visible spectrum
and the eye occupied attention at the second lecture, the varying
lengths of light waves of different colours being referred to, whilst
an artificial rainbow was produced and Newton’s rings were shown
and explained. Illustrations of the effects produced by mixing light
of different colours were followed by an account of complementary
colours, and an additional zest was imparted to the brilliant experi¬
mental display by an exhibition of the animatograph with its
animated photographs.
The Polarisation of Light, so-called, was shown by the
lecturer to be capable of ready explanation, all that is to be
understood by the term being the causation in one particular direc¬
tion of small displacements in the medium through which the light
waves are passing. Ordinary light consists of all colours mixed
together, and also of waves of different polarisations, that is te
say vibrations are taking place in all possible directions. The
effect of “polarising” this light is to alter the direction of the
vibrations, and allow waves to pass which are vibrating in one
direction only, vertical, horizontal, or oblique, as the case may be.
The polarising effects produced by Iceland spar and tourmaline
were shown, as also the wonderful colour changes caused by
passing polarised light through mica, crystals, etc. , and altogether
what is usually regarded as a most abstruse subject was rendered
exceedingly clear.
Electrification of Air by Rontgen Rays has been accom-'
plished by Lord Kelvin, with whom have been associated in his
experiments Dr. J. C. Beattie and Dr. M. Smoluchowski. de
Smolan. In the apparatus, as represented in Nature , the air was
drawn, by means of an air pump, through a lead cylinder closed at
both ends with paraffined cardboard transparent to the Rontgen
rays, and thence through an electric filter. In every case the air
drawn through the filter was found to be negatively electrified
when no screen or an aluminium screen was interposed between the
Rontgen lamp and the near end of the lead cylinder, but the
interposition of a lead screen prevented electrification. A very
decided electrification of air — sometimes negative, sometimes
positive — was also observed when the Rontgen rays were directed
across a glass or aluminium tube, through which the air was being-
drawn from the quadrangle outside the laboratory, to the filter.
The Secretary of the P.A. T.A. is promptly following up his
protest against the position occupied by the Glasgow and West of
Scotland Pharmaceutical Association, in regard to the protection
of prices, by calling a special meeting of the trade in and around
Glasgow, on Tuesday next at 11 a.m., to discuss the aims of the
“anti-cutters.” One result of this carrying war into the enemy’s
camp should be to remove the “ surprising amount of misconcep¬
tion ’’that has struck Mr. Glyn-Jones as existing in the northern
Jan. 9, 1897]
PHARMACEUTICAL JOURNAL.
33
city. But to attain this result he must be severely logical, and
indulge in no metaphors with hidden meanings, as our clear¬
headed friends across the border are apt to take things very
literally. Another meeting, with a similar object, will be held at
Sunderland on the following day, Wednesday, January 13, when
Mr. John Harrison, Vice-President of the Pharmaceutical Society,
will take the chair, and Mr. Glyn- Jones again recite his tale.
Whether or not he is likely to gain the sjunpathy of the Wear-
siders we are unable to say, but he will at least have a fair field,
for Sunderland was one of the first towns to suffer from the ravages
of the cutting-fiend.
The Major Examination Results, published this week
(see p. 34), are decidedly discouraging, even if contrasted only
with the poor average that has prevailed generally of late years.
Thus, the percentages of rejections for the past three years have
been: — 1894, 49 "66; 1895, 53 42 ; and 1896, 53-07, these figures
being, as was observed in last week’s Journal (p. 3), higher than
might reasonably be looked for among persons who have passed
through such a severe ordeal as the Minor examination now
undoubtedly is. On the present occasion, however, the percentage
of rejections at the Major examination has reached 57 '14, a figui'e
which cannot be viewed with equanimity by anyone having the
best interests of British pharmacy at heart. These things are
managed much better on the Continent, where the percentage of
failures does not exceed 5 '0 per cent., if even it reaches that
figure, and the only inference that can be drawn is that there
must be some grave defect in the British system — either of edu¬
cation or of examination. Perhaps, on the whole, it is safe to say
that our examination standard appears to be far above the head
of the average candidate, and there is little reason to doubt
that the cause is defective education and a consequent unfitness
for the position the pharmacist of to-day may reasonably
expect to occupy.
Dr. Oscar Liebreich is to be congratulated on having cele¬
brated, on December 30 last, the twenty-fifth anniversary of his
occupancy of the chair he holds. He was born at Konigsberg,
Prussia, in 1839, and after serving for some time in the mercantile
marine, proceeded to study chemistry under Eresenius at Wies¬
baden. Technical chemistry engaged his attention for a time, but
he then began to study medicine, and graduated at Berlin in 1865.
Six years later he became assistant to Virchow at the Pathological
Institut der Charity, and shortly afterwards extra-ordinary pro¬
fessor at the university. Since the death of Mitscherlich, Dr.
Liebreich has occupied the position of Director of the Pharma¬
cological Institute of the Berlin University. With his assistant,
Dr. Langgard, he has published a compendium of medicine, and
they also jointly edit the Therapeutische Monatshefte, and are now
engaged in publishing an extensive encyclopaedia of therapeutics.
Amongst other work, Liebreich introduced the use of chloral
hydrate as a soporific and revived the use of wool-fat for medicinal
purposes.
‘ The Medical Environment ’ is the title given by Dr. D.
Campbell Black to a little book which consists of reprints of two
addresses delivered by him. The first, on the hospital question,
was delivered before the Anderson’s College Medico-Chirurgical
Society, and deals with certain anomalies in connection with
hospitals. Amongst other points, it is stated that the hospital
system is iniquitous and fraudulent “in the dominance of the
personal interests of the hospital physicians and surgeons,” and
that a system of weeding at “the gate” is practised with the
object of keeping down the death-rate of given wards “ when some
fad is being boomed, or some astute adventurer to be advertised.”
In the second address, delivered before the Saint Mungo Medico-
Chirurgical Society, the author treats of medical ethics or
etiquette. He tilts against the Editor of the British Medical
Journal and his Medico-Ethical Assessor, whose oracular utter¬
ances are undoubtedly such at times as to give occasion for much
scoffing. As a “ very fair example of the metaphysical idiocy of
medical virtue,” the answer is quoted to a question regarding the
propriety of affixing a red lamp to the wall of a medical man’s
house. The use of a red lamp was considered objectionable, but
it was suggested that, if the situation of the house rendered more
light desirable, “ an ordinary or other selected gas lamp, with or
without a reflector, should be so arranged as to throw the light
upon the door or name-plate.” Presumably the “other selected
gas lamp ” might be any other colour than red without infringing
the official code of medical ethics.
“ The Lecture that Failed,” the editor of the Practitioner
heads a paragraph in which he relates how it had been arranged
that Dr. Thorne Thorne should deliver a lecture, under the
auspices of the National Health Society, on the transmission of
typhoid fever by oysters. Large posters had announced the coming
event, and a strong force of fishmongers and others interested in
the oyster trade had mustered on the appointed day. No lecture
was delivered, however, but whether because the officials of the
Society did not altogether like the look of their unusual audience,
or because the medical officer of the Local Government Board
objected to the manner in which his official position had been
“boomed,” is not known.
‘ Studies in Chemical Dynamics,’ by J. H. van ’t Hoff, as re¬
vised and enlarged by Dr. Ernest Cohen, of Amsterdam, has
been translated into English by Dr. Thomas Ewan, of the York¬
shire College, Leeds, and published by Williams and Norgate
London, at half-a-guinea. The original work was published some
thirteen years ago, and the present edition not only reproduces
that, but also presents the researches which have been
engendered by it. The main divisions of the work deal with the
course of chemical change, the influence of temperature on chemi¬
cal change, chemical equilibrium, and affinity.
The Revenue Returns for the first three quarters of the
current financial year show an increase of £1,284,000, all of which
occurred in the first quarter of the year. Customs and Excise
yield a much larger surplus than was anticipated, Estate Duties
and- Stamp have fallen much less than was expected, and other
branches are in an equally satisfactory condition. Unless, there¬
fore, any unforeseen contingency happens, the Chancellor of the
Exchequer should have a handsome surplus to dispose of when he
makes his Budget estimates. Let us hope that the chemist and
druggist may benefit by this happy condition of affairs.
Another Case of Snake-Bite treated with antivenomous serum
is recorded by Professors Keatinge and Ruff'er, in the British
Medical Journal. , but though complete recovery is recorded there
is, as in most cases of this kind, a flaw in the chain of evidence, as
the snake escaped and “it is not possible to say exactly what it
was.” It follows, therefore, that proof is lacking of the assump¬
tion that the snake was “a highly venomous one.” The patient
was a girl of 13, and she was bitten in the forearm. When
seen by the professors, at the School of Medicine, Cairo, some
three or four hours later, she was in a very precarious condition.
Dr. Calmette’s serum was administered and recovery was. complete
in three weeks.
34
PHARMACEUTICAL JOURNAL.
[Jan. 9, 1897
PHARMACEUTICAL SOCIETY.
EXAMINATIONS IN LONDON.
January, 1897.
MAJOR EXAMINATION RESULTS.
Candidates examined . 35
„ failed . 20
,, passed . . . 15
Bowden, Harold.
Brigham, Edwin Beal.
Brown, Charles.
Campkin, Francis Sidney.
Critchley, Charles Albert.
Dann, Charles.
Gooie, Arthur Frederick.
Pitcher.
Greenhalgh, Edmund Parkin? on.
Knight, William Arthur.
Last, George Valentine Chapman
Lloyd, Hugh William.
Masterman, Henry.
Morrell, John George.
Pearson, George Ernest.
James Frederick.
BRITISH ASSOCIATION FOR THE
ADVANCEMENT OF SCIENCE.
- ♦ -
BOTANICAL SECTION.
OPENING ADDRESS BY
D. H. SCOTT, M.A., Ph.D., F.RS.,
Honorary Keeper of the Jodrell Laboratory , Royal Gardens, Kew,
President of the Section.
THE PRESENT' POSITION OF MORPHOLOGICAL BOTANY.
The object of modern morphological botany (the branch of onr
science to which I propose to limit my remarks) is the accurate
comparison of plants, both living and extinct, with the object of
tracing their real relationships with one another, and thus of ulti¬
mately constructing a genealogical tree of the vegetable kingdom.
The problem is thus a purely historical one, and is perfectly distinct
from any of the questions with which physiology has to do.
Yet there is a close relation between these two branches of
biology ; at any rate, to those who maintain the Darwinian position.
For from that point of view we see that all the characters which
the morphologist has to compare are, or have been, adaptive. Hence
it is impossible for the morphologist to ignore the functions of
those organs of which he is studying the homologies. To those
who accept the origin of species by variation and natural selection
there are no such things as morphological characters pure and
simple. There are not two distinct categories of characters — a
morphological and a physiological category — for all characters
alike are physiological. “ According to thao theory, every organ,
every part, colour, and peculiarity of an organism must either be of
benefit to an organism itself, or have been so to its ancestors. . . .
Necessarily, according to the theory of natural selection, structures
either are present because they are selected as useful, or because
they are still inherited from ancestors to whom they were useful,
though no longer useful to the existing representatives of those
ancestors.”*
The useful characters may have become fixed in comparatively
recent times, or a long way back in the past. In the latter case
the character in question may have become the property of a large
group, and thus, as we say, may have become morphologically
important.
For instance, parasitic characters, such as the suppression of
chlorophyll, are equally adapUve in Dodder and in the Fungi. In
Dodder, however, such characters are of recent origin and of little
morphological importance, not hindering us from placing the genus
in the natural order Convolvulacese ; while in Fungi equally adap¬
tive characters have become the common property of a great class
of plants.
* Lankester, ‘Advancement of Science,’ p. 307.
Then, again, the existence of a definite sporophyte generation ?
which is the great character of all the higher plants, is in certain
Fungi inconstant, even among members of the same species.
Although there is no essential difference between adaptive and
morphological characters, there is a great difference in the morpho¬
logist’s and the physiologist’s way of looking at them. The physio¬
logist is interested in the question how organs work ; the morpho¬
logist asks, what is their history ?
The morphologist may well feel discouraged at the vastness of
the work before him. The origin of the great groups of plants is
perhaps, after all, an insoluble problem, for the question is not
accessible either to observation or experiment.
All that we can directly observe or experiment upon is the
occurrence of variations — perhaps the most important line of
research in biology, for it was the study of variation that led
Darwin and Wallace to their grand generalisation. Many observers
are working to-day in the spirit of the great masters, and it is
certain that their work will be fruitful in results. It is evident,
however, that such investigations can at most only throw a side
light on the historical question of the origin of the existing orders
and classes of living things. The morphologist has to attack such
questions by other methods of research.
The embryological method has so far scarcely received justice
from botanists. A great deal of what is called embryology in
botany is not embryology at all, but relates to pre-fertilisation
changes. Of real embryology — that is to say, the development of
the young plant from the fertilised ovum — there is much less than
we might expect. Thus no comparative investigation of the
embryology of either dicotyledons or monocotyledons has ever been
carried out, our knowledge being entirely based on a few isolated
examples.
In the cases which have been investigated, perhaps excessive
attention has been devoted to the first divisions of the ovum, the
importance of which, as Sachs long ago showed, has been overrated,
while the later stages, when the differentiation of organs and
tissues is actually in progress, have been comparatively neglected.
The law of recapitulation (or repetition of phytogeny in ontogeny)
has been very inadequately tested in the vegetable kingdom. What¬
ever its value may be, it is certainly desirable that the development
of plants as well as animals shoffid be considered from this point
of view ; and this has so far been done in but very few cases. M.
Maisart, of Brussels, has made some investigations with this object,
on the development of seedlings and if individual leaves. He is
led to the conclusion that examples of recapitulation are rare among
plants.*
So far, at least, embryological research has only yielded certain
proof of recapitulation in a few cases, as in the well-known example
of the phyllode- bearing acacias, in which the first leaves of the
seedling are normal, while the later-formed ones gradually assume
the reduced phyllode form.
A less familiar example is afforded by Gunnera. Here, as is well
known, the mature stem has a structure totally different from that
of ordinary dicotyledons, and much resembling that characteristic
of most ferns. In most species of Gunnera there are a number
of distinct vascular cylii dtrs in the stem, instead of one only, and
there is never the slightest trace, so far as the adult plant is con¬
cerned, of the growth by means of cambium, which is otherwise so>
general in the class. The seedling stem, however, is not only
monostelic below the cotyledons, but in this region, though nowhere
else, shows distinct secondary growth. Thus, if we were in any doubt
as to the general affinities of Gunnera, owing to its extraordinary
mature structure, we should at once be put on the right track by
the study of the embryonic stem, which alone retains the charac¬
teristic dicotyledonous mode of growth.
It is only in a few cases, however, and for narrow ranges of
affinity, that the doctrine of recapitulation has at present helped
in the determination of relationships among plants. Beyond this,
conclusions based on embryology alone tend to become merely
conjectural and subjective. In fact, all comparative work, in so far
as it is limited to plants now living, suffers under the same
weakness that it can never yield certain results, for the question
whether given characters are relatively primitive or recently ac¬
quired is one upon which each naturalist is left to form his own
opinion, as the origin of the characters cannot be observed.
To determine the blood-relationships of organisms it is necessary
to decipher their past history, and the best evidence we can have
* ‘ La Recapitulation et l’lnnovation en Embryologie Vegetale,,’'
Bull, de la Soc. roy. de Bot. de Belgique, vol. xxxiii., 1894.
Jan. 9, 1897]
PHARMACEUTICAL JOURNAL.
35
(when we can get it) is from the ancient organisms themselves
The problem of the morphologist is an historical one, and con¬
temporary documentary evidence is necessarily the best. It is
palaeontology alone which can give us the real historical facts.
Anatomical Characters.
In judging of the affinities of fossil plants we are often compelled
to make great use of vegetative characters, and more particularly
of characters drawn from anatomical structure. It is true that in
many cases we do so because we cannot help ourselves, such
anatomical features being the only characters available in many of
the specimens as at present known. But the value of the method
has been amply proved in other cases where the reproductive
structures have also been discovered, and are found to fully confirm
the conclusions based on anatomy. I need only mention the great
groups of the Lepidodendrere and the Calamites, in each of which the
anatomical characters, when accurately known, put us at once on
the right track, and lead to results which are only confirmed by the
study of the reproductive organs.
In this matter fossil botany is likely to react in a beneficial way
on the study of recent plants, calling attention to points of structure
which have been passed over, and showing us the value of characters
of a kind to which systematists had until recently paid but little
attention. At present, owing to the work of Radlkofer, Vesque,
and others, anatomical characters are gradually coming into use in
the classification of the higher plants, and in some quarters there
may even be a tendency to over-estimate their importance. Such
exa'geration, however, is only a temporary fault incident to the
introduction of a comparatively new method. In the long run
nothing but good can result from the effort to place our classification
on a broader basis. In most cases the employment of additional
characters will doubtless serve only to further confirm the affinities
already detected by the acumen of the older taxonomists. There
are plenty of doubtful points, however, where new light is much
needed ; and even where the classification is not affected it will be
a great scientific gain to know that its divisions are based on a
comparison of the whole structure, and not merely on that of
particular organs.
The fact that anatomical characters are adaptive is undeniable,
but this applies to all characters, such difference as there is being
merely one of degree. Cases are not wanting where the vegetative
tissues show greater constancy than the organs of reproduction, as,
for example, in the Marattiacese, where there is a great uniformity
in anatomical structure throughout the family, while the sporangia
show the important differences on which the distinction of the
genera is based. It is, in fact, a mistake to suppose that anatomical
characters are neces arily the expression of recent adaptations. On
the contrary, it is easy to cite examples of marked anatomical pecu¬
liarities which have become the common property of large groups of
plants.
For instance, to take a case in which I happen to have been
specially interested, the presence of bast to the inside as well as to
the outside of the woody zone is a modification of dicotyledonous
struture, which is in many groups at least of ordinal value. The
peculiarity is constant throughout the orders Onagracese, Lythraceae,
Myrtaceas, Solanacese, Asclepiadacete, and Apocynaceao, not to men¬
tion some less important groups. In other families, such as the
Cucurbitaceaa and the Gentianeae, it is nearly constant throughout
the order, but subject to some exceptions. Among the Composites
a similar, if not identical, peculiarity appears in some of the sub¬
order Cichoriacese, but is here not of more than generic value. In
Campanula the systematic importance of internal phloem is even
less, for it appears in some species and not in others. Lastly, there
are cases in which a similar character actually appears as an
individual variation, as in Carum carvi, and, under abnormal condi¬
tions, in Phaeeolus multiflorus.
These latter cases seem to me worthy of special study, for in
them we can trace, under our very eyes, the first rise of anatomical
characters which have elsewhere become of high taxonomic im¬
portance. A comparative study of the anatomy of any group of
British plants, taking the same species growing under different
conditions, would be sure to yield interesting results if any one
had the patience to undertake it.
Enough has been said to show that a given anatomical character
may be of a high degree of constancy in one group while extremely
variable in another, a fact which is already perfectly familiar as
regards the ordinary morphological characters. For example,
nothing is more important in phanerogamic classification than the
arrangement of the floral organs as shown in ground-plan or floral
diagram. Yet Professor Trail’s observations, which he has been
good enough to communicate to me, show that in one and the same
species, or even individual, of Polygonum, almost every conceivable
variation of the floral diagram may be found.
There is, in facL, no “ royal road ” to the estimation of the relative
importance of charac‘ers; the same character which is of the
greatest value in one group may be trivial in another; and this
holds good equally whether the character be drawn from the
external morphology or from the internal structure.
Oar knowledge of the comparative anatomy of plants, from this
point of view, is still very backward, and it is quite possible that
the introduction of such characters into the ordinary work of the
herbarium may be premature ; certainly it must be conducted with
the greatest j idgment and caution. We have not yet got our data,
but every encouragement should be given to the collection of such
data, so that our classification in the future may rest on the broad
foundation of a comparison of the entire structure of plants.
In estimating the relative importance of characters of different
kinds we must not forget that characters are often most constant
when most adaptive. Thus, as Professor Trail informs me, the
immense variability of the flowers of Polygonum goes together
with their simple method of self-fertilisation. The exact arrange¬
ment i3 of little importance to the plant, and so variation goes on
unchecked. In flowers with accurate adaptation to fertilisation by
insects such variability is not found, for any change which would
disturb the perfection of ths mechanism is at once eliminated by
natural selection.
Histology.
I propose to say but little on questions of minute histology, a
subject which lies on the bo'derland between morphology and
physiology, and which will be dealt with next Tuesday far more
competently than I could hope to treat it. Last year my prede¬
cessor in the presidency of this section spoke of a histological dis¬
covery (that of the nucleus, by Robert Brown) as “ the most epoch-
makiDg of events” in the modern history of botany. The histological
questions before us at the present day may be of no less importance,
but we cannot as yet see them in proper perspective. The centro-
somes, those mysterious protoplasmic particles which have been
supposed to preside over the division of the nucleus, and thus to
determine the plane of segmentation, if really permanent organs of
the cell, would have to rank as co-equal with the nucleus itself. If,
on the other hand, as some think, they aie not constant morpho¬
logical entities, but at most temporary structures differentiated ad
hoc, then we are brought face to face with the question whether the
causes of nuclear division lie in the nucleus itself or in the surround¬
ing protop1 asm.
Nothing can be more fascinating than such problems, and nothing
more difficult. We have, at any rate, reason to congratulate our¬
selves that English botanists are no longer neglecting the study of
the nucleus and its relation to the cell. For a long time little was
done in these subjects in our country, or, at least, little was pub¬
lished, and botanists were generally content to take their informa¬
tion from abroad, not going beyond a mere verification of other
men’s results. Now we have changed all that, as the communica¬
tions to this section sufficiently testify.
Nothing is more remarkable in histology than the detailed agree¬
ment in the structure and behaviour of the nucleus in the higher
plants and the higher animals, an agreement which is conspicuously
manifest in those special divisions which take place during the
maturation of the sexual cells. Is this striking agreement the
product of inheritance from common ancestors, or is the paral¬
lelism dependent solely on similar physical conditions in the cells ?
This is one of the great questions upon which we may hope for new
light from a histological discussion of the matter,
Alternation of Generations.
We have known ever since the great discoveries of Hofmeister
that the development of a large part of the vegetable kingdom
involves a regular alternation of two distinct generations, the one,
which is sexual, being constantly succeeded — so far as the normal
cycle is concerned — by the other which is asexual. This alterna¬
tion is most marked in the mosses and ferns, taking these words in
their widest sense, as used by Professor Campbell in his recent
excellent book. In the Bryophyta, the ordinary moss or liverwort
plant is the sexual generation, producing the ovum, which, when
fertilised, gives rise to the moss-fruit, which here alone represents
the asexual stage. The latter forms spores from which the sexual
plant is again developed.
36
PHARMACEUTICAL JOURNAL.
[Jan. 9. 1897
In the Pteridophyta the alternation is equally regular, but the
relative development of the two generations is totally different, the
sexual form being the insignificant prothallus, while the whole fern-
plant, as we ordinarily know it, is the asexual generation.
The thallus of some of the lower Bryophyta is quite comparable
with the prothallus of a fern, so as regards the sexual generation
there is no difficulty in seeing the relation of the two classes ; but
when we come to the asexual generation or sporophyte the case is
totaPy different. There is no appreciable resemblance between the
fruit of any of the Bryophyta and the plant of any vascular
Cryptogam.
There is thus a great gap within the Archegonia^ac ; there is
another at the base of the series, for the regular alternation of the
Bryophyta is missing in the Algae and Fungi, and the question as
to what corresponds among these lower groups to the sporophyte
and oophyte of the higher Cryptogams is still disputed.
Now as regards this life-cycle, which is characteristic of all plants
higher than Algse and Fungi, there are two great questions at
present open. The one is general: Are the two generations, the
sporophyte and the oophyte, homologous with one another, or is the
sporophyte a new formation intercalated in the life-history, and not
comparable to the sexual plant? The former kind of alternation
has been called homologous, the latter antithetic. This question
involves the origin of alternation ; its solution would help us to
bridge over the gap between the Archegonial se and the lower plants.
The second problem is more special : Has the sporophyte of the
Pteridophyta, which always appears as a complete plant, been
derived from the simple and totally different sporophyte of the
Bryophyta, or are the two of distinct origin ?
At present it is usual, at any rate in England, to assume the anti¬
thetic theory of alternation. ProFessor Bower, its chief exponent,
says :* “ It will also be assumed that, whatever may have been the
circumstances which led to it, antithetic alternation was brought
about by elaboration of the zygote [i e., the fertilised ovum] so as to
form a new generation (the sporophyte) interpolated between suc¬
cessive gametophytes, and that the neutral generation is not in any
sense the result of modification or metamorphosis of the sexual,
but a new product having a distinct phylogenetic history of its
own.” In his essay on “ Antithetic as Distinguished from Homo¬
logous Alternation of Generations in Plants, vf the author describes
the hypothetical first appearance of the sporophyte as follows:
“ Once fertilised, a zygote might in these plants [the first land
plants] divide up into a number of portions (carpospores), each of
which would then serve as a starting-point of a new individual.”
On this view, the sporophyte first appeared as a mere group of
spores formed by the division of the fertilised ovum. Consequently
the inference is drawn that all the vegetative parts of the sporo¬
phyte have arisen by the “ sterilisation of potentially sporogenous
tissue.” That is to say, there was nothing but a mass of spores to
start with, so whatever other tissues and organs the sporophyte
may form must be derived from the conversion of spore-forming
cells into vegetative cells. Professor Bower has worked out this
view most thoroughly, and as the result he is not only giving us the
most complete account of the development of sporangia which we
have ever had, but he has also done much to clear up our ideas, and
to show us what the course of evolution ought to have been if the
assumptions required by the antithetic theory were justified.
Without entering into any detailed criticism of this important
contribution to morphology, which is still in progress, I wish to
point out that we are not, after all, bound to accept the assumption
on which the theory rests. There is another view in the field, for
which, in my opinion, much is to be said. The antithetic theory is
receiving a most severe test at the friendly hands of its chief
advocate. Should it break down under the strain we need not
despair, for another hypothesis remains which I think quite equally
worthy of verification.
This is the theory of Pringsheim, according to which the two
generations are homologous one with another, the oophyte corre¬
sponding to a sexual individual among Thallophytes, the sporo¬
phyte to an asexual individual. To quote Pringsheim’s own words : X
“The alternation of generations in mosses is immediately related to
those phenomena of the succession of free generations in Thallo¬
phytes, of which the one represents the neutral, the other the
sexual plant.” Further on§ he illustrates this by sajing: “The
# “ Spore -producing Members,” Phil. Trans., vol. clxxxv. B. (1894),
p. 473.
t Annals of Botany, vol. iv. (1890), p. 362.
X Gesammelte Abhandlungen, ii., p. 370.
§ Ibid., p. 371.
moss sporogonium stands in about the same relation to the moss
plant as the sporangium-bearing specimens of Saprolegnia, stand to
those which bear oogonia, or as, among the Floridese the specimens
with tetraspores are related to those with cystocarps.” This gets
rid of the intercalation of a new generation altogether ; we only
require the modification of the already existing sexual and asexual
forms of the Thallophytes.
The sudden appearance of something completely new in the life-
history, as required by the antithetic theory, has, to my mind, a
certain improbability. Ex nihilo nihil fit. We are not accustomed
in natural history to see brand-new structures appearing, like mor¬
phological Melchizedeks, without father or mother. Nature is con¬
servative, and when a new organ is to be formed it is, as every one
knows, almost always fashioned out of some pre-existing organ.
Hence I feel a certain d fficulty in accepting the doctrine of the
appearance of an intercalated sporophyte by a kind of special
creation.
We can have no direct knowledge of the origin of the sporophyte
in the Bryophyta themselves, for the stages, whatever they may
have been, are hopelessly lost. In some of the Algae, however, we
find what most botanists recognise as at least a parallel develop¬
ment, even if not phylogenetically identical.* Ia CEdogonium, for
example, the oospore does not at once germinate into a new plant,
but divides up into four active zoospores, which swim about and
then germinate. In Goleochoste the oospore actually becomes par¬
titioned up by cell- walls into a little mass of tissue, each cell of
which then gives ri?e to a zoospore.
In both these genera (and many more might he added) the cell-
formation in the germinating oospore has been generally regarded!
as representing the formation of a rudimentary sporophyte genera¬
tion. If we are to apply the antithetic theory of alternation to
these cases, we must assume that the zoospores produced on ger¬
mination are a new formation, intercalated at this point of the
life-cycle. But is this assumption borne out by the facts ? I think
not. In reality nothing new is intercalated at all. The “ zoospores ”
formed from the 06 -spore on germination are identical with the so-
called “ zoogonidia,” formed on the ordinary vegetative plant at all
stages of its growth.
In science, as in every subject, we too easily become the slaves of
language. By giving things different names we do not prove that
the things themselves are different. In this case, for example, the
multiplication of terms serves, in my opinion, merely to disguise
the facts. The reproductive cells produced by the ordinary plant
of an CEdogonium are identical in development, structure, behaviour,
and germination with those produced by the oospore. The term
“ zoogonidia ” applied to the former is a “ question-begging epithet,”
for it assumes that they are not homologous with the “zoospores ”
produced by the latter. I prefer to keep the old name zoospore for
both, as they are identical bodies.
To my mind the point seems to be this. An CEdogonium (to keep
to this example) can form zoospores at any stage of its develop¬
ment ; there is one particular stage, however, at which they are
alwajs formed— namely, on the germination of the cospore. Nothing
new is intercalated, but the irregular and indefinite succession of
sexual and asexual acts of reproduction is here tending to become
regular and definite.
In Sphceroplea, as was well pointed out bv the late Mr. Yaiz?y,f
though bis view of alternation was very different from that which
I am now putting forward, the alternation is as definite as in a moss,
for here, so far as we know, zrospores are only formed on the ger¬
mination of the fertilised ovum. If Sphceroplea stood alone we
might believe in the intercalation of these zoospores, as a new stage,
but the comparison with Ulothrix, CEdogonium , Bulbochwte, and
Coleochcete shows, I think, where they came from.
The body formed from the oospore i3 called by Pringsheim the
first neutral generation. In CEdogonium this has no vegetative
development, for the first thing that the oospore dees is to form the
asexual zoospores, and it is completely used up in the process. In
other cases it is not in quite such a hurry, and here the first neutral
generation has time to show itself as an actual plant. This is so in
Ulothrix, a much more primitive form than CEdogonium, for its
sexuality is not yet completely fixed. Here the zygospore actually
germinates, forming a dwarf plant, and in this stage passes through
the dull seasoD, producing zoospores when the weather becomes
more favourable. On Pringsheim’s view the dwarf plant is not a
new creation, but just a rudimentary Ulothrix, which soon passes
* See Bower, ‘ Antithetic Alternation,’ p. 361.
t ‘ Annals of Botany/ vol. iv., p. 373.
Jan. 9, 1-8973
PHARMACEUTICAL JOURNAL
37-
on to spore-formation. So, too, with the cellular body formed on
the germination of the oospore of Coleochcete ; this also is looked
upon as a reduced form of thallus. On any view this genus is
especially interesting, for the sporopbyte remains enclosed by the
tissue of the sexual generation, thus offering a striking analogy with
the Bryopbyta.
In the Phycomycetous Fungi — plants which have lost their
chlorophyll, but which otherwise in many cases scarcely differ from
Algas — the oospore in one and the same species may either form a
normal mycelium, or a rudimentary mycelium bearing a sporan¬
gium, or may itself turn at once into a sporangium (producing
zoospores) without any vegetative development. Here it seems
certain that Pringsheim’s view is the right one, for all stages in the
reduction of the first neutral generation lie before our eyes.
Nowhere, either here or among the green Algse, do I see aDy
evidence for the intercalation of a new generation or a new form of
spore on the germination of the fertilised ovum.
Pringsheim extends the same view to the higher plants. The
sporogonium of a moss is for him the highly modified first neutral
generation, homologous with the vegetative plant, but here specially
adapted for spore-formation. I have elsewhere pointed out* that
this view has great advantages, for not only does it harmonise
-exactly with the actual facts observed in the green Algse and their
allies, but it also helps us to understand the astoundingly different
forms which the archegoniate sporophyte may assume.
It seems to me that Pringsheim was right in regarding the fruit-
formation of Floridese as totally different from the sporopbyte-
■formation of Coleochcete or the Bryophyta. The cystocarp bears
none of the marks of a distinct generation, for throughout its
whole development it remains in the most complete organic connec¬
tion with the thallus that bears it. The whole Floridean process,
-often so complicated, appears to be an arrangement for effecting the
fertilisation of many female cells as the result of an original
impregnation by a single sperm cell. There is here still a great
field for future research ; but in the light of our present knowledge
there seems to be no real parallelism with the formation of a sporo-
p>hyte in the higher plants.
The gap between the Bryophyta and the Algse remains, unfor¬
tunately, a wide and deep one, and it is not probable that any Algse
at present known to us lie at all near the line of descent of the
•higher Cryptogams. Riccia is often compared with Coleochcete, but
it is by no means evident that Riccia is a specially primitive form.
Sn Anthoceros, which bears some marks of an archaic character, the
sporophyte is relatively well developed. To those who do not
accept the theory of intercalation it is not necessary to assume
that the most primitive Bryophyta must have the most rudimentary
sporophyte.
Apart from other differences, Bryophyta differ from most green
Algae in the fact that asexual spores are only found in the genera¬
tion succeeding fertilisation. The spores, moreover, are themselves
•quite different from anything in Algae, and the constancy of their
formation in fours among all the higher plants from the liverworts
upwards, is a fact which requires explanation. I should like to
suggest to some energetic histologist a comparison of the details of
spore-formation in the lower liverworts and in the various groups of
Algse, especially those of the green series. It is possible that some
light might be thus thrown on the origin of tetrad-spore-formation,
a subject as to which Professor Farmer has already gained some
very remarkable results. On Pringsheim’s view some indications of
homology between bryophytic and algal spore-formation might be
•exprcted, and anyhow the tetrads require some explanation.
The peculiarities of the sporophyte in the Archegoniatre, as com¬
pared with any algal structures, depend, no doubt, on the acquire¬
ment of a terrestrial habit, while the cophyte by its mode of
fertilisation remains “tied down to a semi-aquatic life.’’f Professor
Bower’s phrase “amphibious alternation” expresses this view of
the case very happily, and indeed his whole account of the rise of
the sporophyte is of the highest value, even though we may not
accept his assumption as to its origin de novo.
I attach special weight to Professor Bower’s treatment of this
Subject, because he has shown how the most important of all
morphological phenomena in plants, namely, the alternation of
generations in Archegoniatac, may be explained as purely adaptive in
origin. All Darwinians owe him a debt of gratitude for this demon¬
stration, which holds good even if we believe the sporophyte to be
the modification of a pre-existing body, and not a new formation.
Apospory and Apogamy.
We must remember that the theory of homologous alternation
has twice received the strongest confirmation of which a scientific
hypothesis is susceptible — that of verified prediction. .In both
cases Pringsheim was the happy prophet. Convinced on structural
grounds of the homology of the two generations in mosses, he
undertook his experiments on the moss fruits, in the hope, as he
says,* that he would succeed in producing protonema from the
subdivided seta of the mosses, and thus prove the morphological
agreement of seta and moss stem. His experiment, as everybody
knows, was completely successful, and resulted in the first
observed cases of apospory, i.e., the direct outgrowth of the sexual
from the asexual generation.
Here he furnished his own verification ; in the second case it has
come from other hands. In the paper of 1877, so often referred to,
he says (p. 391): “Here, however [i.e., in the ferns], the act of
generation, that is, the formation of sexual organs and the origin
of an embryo, is undoubtedly hound' up with the existence of the
spore, until those future ferns are found which I indicated as con¬
ceivable in my preliminary notice, in which the prothallus will
sprout forth directly from the frond.”
It is unnecessary to remind English botanists that Pringsheim’s
hypothetical aposporous ferns are now perfectly well known in the
flesh ; such cases having been first observed by Mr. Druery and
then fully investigated by Professor Bower.
A very remarkable case of direct origin of the oophyte from
the sporophyte has lately been described by Mr. E. J. Lowe in a
variety of Scolopendrium vidgare. Here the young fern-plant
produced prothalli bearing archegonia as direct outgrowths from
its second or third frond. The specimen had a remarkable history,
for the young plants were produced from portions of a prothallus
which had been kept alive and repeatedly subdivided during a
period of no less than eight years. I cannot go into the interest¬
ing details here, they will be published elsewhere ; but I wish to
call attention to the fact that in this case the production of the
sexual from the asexual generation, occurring so early in life, has
no obvious relation to suppressed spore-formation, and so appears
to differ essentially from the cases first described , which occurred
on mature plants. I believe Mr. Lowe’s case is not an altogether
isolated one.
The converse phenomenon — that of apogamy — or the direct
origin of an asexual plant from the prothallus, without the inter¬
vention of sexual organs, has now been observed in a considerable
number of ferns, the examples already known belonging to no less
than four distinct families: Polypodiaceee, Parkeriacese, Osmund-
acere, and Hymenophyllacese. In Trichomanes alatum Professor
Bower found that apospory and apogamy co-exist in the same
plant, the sporophyte directly giving rise to a prothallus, which
again directly grows out into a sporophyte ; the life-cycle is thus
completed without the aid either of spores or of sexual organs.
Dr. W. H. Lang, who has recently made many interesting obser¬
vations on apogamy, will, I am glad to say, read a paper on the
subject before this section, so I need say no more.
I must, however, express my own conviction that the facility
with which, in ferns, the one generation may pass over into the
other by vegetative growth, and that in both directions, is a most
significant fact. It shows that there is no such hard and fast dis¬
tinction between the generations as the antithetic theory would
appear to demand, and in my opinion weighs heavily on the side
of the homology of sporophyte and cophyte. I cannot but think
that the phenomena deserve greater attention from this point of
view than they have yet received.
A mode of growth which affords a perfectly efficient means of
abundant propagation cannot, I think, be dismissed as merely
teratological.
Since the foregoing paragraph was first written Dr. Lang has
made the remarkable discovery (already communicated to the
Royal Society) that in a Lastraea sporangia of normal structure are
produced on the prothallus itself, side by side with normal
archegonia and antheridia. I cannot forbear mentioning this
striking observation, of which we shall hear an account from the
discoverer himself.
The strongest advocate of the homology of the prothallus with
the fern plant could scarcely have ventured to anticipate such a
discovery.
( To he continued.')
* Nature, February 21, 1895.
-+ Bower, ‘ Antithetic Alternation.’
* ‘ Ges. Abh.’ ii., p. 407.
38
PHARMACEUTICAL JOURNAL.
[Jan. 9, 1897
EXTRACTS FROM CONSULAR REPORTS-
Olive Oil. — In May, 1890, a concession was granted by the
Persian Government to Messrs. Konssis and Theophilactos, a Greek
firm under Russian protection, giving them a monopoly for the
purchase and working of all the olives in Northern Persia. This is
only now being put into operation by the establishment of a
properly-constituted factory on the most approved system. The
firm intend to induce the owners of olive groves to sell them
their entire crops, by offering them more remunerative prices than
they have hitherto obtained. They will manufacture table olive
oil of the best quality with the greater part of the olives, the
residue being used for soap-making. With their machinery they
will be able to extract the whole of the oil from the olives, which
is far from the case by the present primitive methods. — ‘Foreign
C ffice Report,’ No. 407.
Mineral Waters. — Consul W. S. H. Gastrell, in his report on
the trade of Teneriffe, says there are several mineral springs in this
island, the water from which, if properly collected and bottled,
would form a very large source of revenue ; but the enormous pro¬
portions to which this trade has been developed on the Continent,
render it useless for any but large capitalists or joint stock com¬
panies to attempt a development, since the expense of advertising
them and putting them on the market is so great. The principal
of these springs is the “Firgas” spring, which has an analysis
equal or superior to any of the table waters of the Continent, and
its habitual use is not found so lowering as many of those, whilst
its pleasant flavour and natural effervescence make it very popular
among the visitors here, used alone or combined with spirits.
There is, no doubt, in this direction a good opening for capital,
since the greater bulk of these waters are used in the United States
of America, to the ports of which country a large majority of the
steamers, which discharge coal at the coaling stations in Puerto
Lrz, proceed in ballast, and would be very glad to offer very low
freights for a new and constant trade, which would mean to ship¬
owners a reduction in the expenses of a round vojage. — ‘Foreign
Office Report,’ No. 1828.
Soap Making in Persia. — Consul Churchill, reporting on the
olive cultivation in the districts of Ghilan, gives an interesting
account of the native method of soap making. When in late
autumn the olives are ripe or black, they are collected by shaking
the trees and striking the branches in the same manner as walnuts
are obtained. The olives, when collected, are boiled for an hour,
they are then dried in the sun. After this they are pressed under
foot in a trough, which reduces the olives to a paste. The paste is
then placed in an earthenware jar and heated; it is afterwards
placed in bags and pressed, when the oil is extracted. This oil is
kept several months in jars, and can be kept for years without
deteriorating. In order to make soap they purchase “kaliab ” or
alkali in Taroum ; they have lime on the spot. The following pro¬
portions are used for making the soap.
Lime . _ . 4 parts.
Alkali . . . . „ . 10 „
Olive Oil . 12 „
Salt . 1 „
There are about ten houses where soap is manufactured in the
village of Kilishter. The best soap is made in this village. Since
the price of olive oil has risen, suet is added in equal proportions to
olive oil in soap making. The prices are : —
Per Man of 17 lbs.
Alkali . 1 kran.
Olive Oil . 18 krans.
Animal Fat (Suet) . 12 ,,
Salt . J kran.
The soap made without the addition of suet is, when kept, of an
excellent quality and well adapted for washing clothes and rough
work generally. — ‘ Foreign Office Report,’ No. 407.
English Trade in Drugs with the Canary Islands.—
The consular report for November gives a list of principal duty¬
free goods imported at Santa Cruz in 1895 from various
countries, among which drugs appear. The total quantity of drugs
imported was 145,230 kilos. ; from England 82,280 kilos., France
47,370 kilos., and from Germany 15,580 kilos. It is satisfactory to
see that Great Britain supplies the bulk also of the remaining
imports. — ‘ Foreign Office Report,’ No. 1828,
All Articles, Letters, Notices, and Reports Intended for
publication in the Journal, Books for Review, and com¬
munications respecting Editorial matter generally,
must, be Addressed “Editor, 17, Bloomsbury Square,
London,” and not in any case to individuals supposed
to be connected with the Editorial Staff. Communica¬
tions for the Current Week’s Journal should reach the
Office not later than Wednesday, but news can be Re¬
ceived by Telegraph until 4 p.m. on Thursday.
Correspondents who wish notice to be taken of their communications must
write in ink, on one side of the paper only, and should authenticate the
matter sent with their names and addresses — of course not necessarily for
publication. No notice can be taken of anonymous communications.
Names and Formulae should be written with extra care, all systematic
names of plants and animals being underlined, and capital letters used to
commence generic but not specific names.
Ant Instructions from Members, Associates, and Students of the PI a -ma~
ceutical Society, with reference to the transmission of the Journal*
should be sent to the Secretary — Mr. Richard Bremridge, — 17, Blooms¬
bury Square, London.
Business communications — including advertisements, orders for copies of the
Journal, and instructions from Subscribers respecting transmission of
same— must be addressed to the Publishers, 5, Serle Street, Lincoln’s Inn,
London. Cheques and money orders should be made payable to “Street
Brothers.”
Drawings for illustrations should be executed twice the desir ed size ; clean
sharp lines being drawn with a pen and liquid Chinese ink. Shading by
washes is inadmissible. Photographs can he utilised in certain cases.
Reprints of articles cannot be supplied unless authors communicate with
the Editor before publication.
Chemists and Company Legislation.
Sir, — A few clays ago I had an interview with our local Member
of Parliament, and called his attention to the Companies Bill intro¬
duced into the House of Lords last session. I found in conversa¬
tion that he knew little about our Act of Parliament passed some
thirty years ago, or how company trading has jumped through
that Act with a coach and four. I explained to him all the points
of the case, in which he was very interested, and asked him to be
kind enough to use what influence he had in helping the Bill for¬
ward when it comes into the House again next session. He
thanked me for the information that I had given him, and said he
had wondered how it was that a “company” could carry on a.
chemist’s business. He said that he would go into the matter and
do what he could. Now my object in writing to you, sir, is to-
urge all local secretaries to see their representatives in Parliament,
or, still better, members of the House of Lords, to explain the case
to them and to ask them for their support to help the qualified
chemist. This can best be given by aiding the Council of the
Pharmaceutical Society and other public bodies in securing the
insertion in any Companies Bill of a special clause prohibiting cor¬
porations doing what individuals are not allowed to do.
Grantham, December SO, 1896. Wm. Whysall.
The Protection of Prices.
Sir, — Like Mr. Park, of Plymouth, I have been much surprised
that the Pharmaceutical Journal has not contained any corre¬
spondence on the topic that is certainly engrossing much of the
time and thoughts of some of the energetic and younger members
of our so-called profession, viz., “the protection of the price of
proprietaries.” The necessity of an appeal on behalf of the
Benevolent Fund clearly indicates to me as an old local secretary
that in consequence of severe competition and selling in many
instances below cost price, the funds of our deserving charities
have fallen off, and this view is further emphasised by your leader
in last week’s J ournal, in which you point out that the sums already
received have been sent by those who already subscribe. In can¬
vassing for subscriptions I have found in prosperous times a readi¬
ness to give to the Benevolent F und even by those who are not
members of the Pharmaceutical Society ; indeed, I might say
further, who ridicule the utility of such membership. The
P.A.T.A. movement is one deserving of the support of all chemists
who honestly wish to better their own position, and in bettering
their own to assist their brother chemist in so doing ; but, like all
new movements, it has been treated with contumely and ridicule
by many of those to whom we generally look to guide us in all
matters appertaining to the welfare of the trade. The names of
Jan. 9, 1897.]
PHARMACEUTICAL JO UR N A L.
39
those who have done so much to earn for the Society as an educa-
cational body the respect that is shown it by kindred bodies are
sadly missing from the ranks of this trade-assisting Association.
The list of protected articles is growing, but month by month those
who are interested in the movement, and who do not wish to leave
one stone unturned that will bring ultimate success, look for
such articles as Dinneford’s magnesia and peppermint water,
Benger’s liquor pancreaticus, pepticus, and food, Collis
Browne’s chlorodyne, Parrish’s food, Steedman’s powders, and
many others, all made by prominent chemists who, we believe, are
anxious for the welfare of their weaker brethren. The P.A.T.A.
has already accomplished much, but if the fathers of the trade
would help us by joining its ranks and putting their preparations on
the protected list, those of the trade who are still lethargic, and
give as an excuse that the great lights in pharmacy are opposed to
the movement, would be convinced and would follow in their foot¬
steps. For years I have worked for the Society, and have con¬
stantly urged on all the necessity of membership, but on the trade
side I have met with the greatest obstacles, and these will increase
rather than lessen, unless the prominent members assist to the
greatest of their power any movement that has for its object the
protection of the articles so many of us are bound to look to if we
Are to make a livinsr.
©
Leamington, December 30, 1S96. J. T. Barrett.
The Flowers of January.
Sir, — It may interest some of your readers to hear that catkins
of the hazel with fully-developed pollen were gathered on January 3
in the neighbourhood of Croydon, and as might be expected, the
crimson stigmas of the female flowers were also found. I have
Also a plant of Helleborus fcetidus in full bloom in my garden.
7, Belgrave Mansions, W. Murton Holmes.
Grosvenor Gardens, S. W., January 3, 1897.
Sir, — Your note on the “Flowers of January” reminds me that
I have never seen a more luxuriant bloom of Petasites fragrans than
was to be seen on the 1st inst. , within a stone’s throw of our
busiest street — produced by the mild bright weather. I have
been driven to consult my calendars for the past nineteen years,
and it may interest some of your readers to have the record of the
plants, and the number of times I have found them in or before
January during those years. It does not follow that more plants
have not flowered, or that these have not flowered oftener, but
only that I have not noted them. The list is as follows : —
Ranunculus acris, nine times ; R. ficaria, 3 ; Helleborus fcetidus, 1 ;
Cheiranthus cheiri, 8 ; Car damme hirsuta, 6 ; Alliaria officinalis, 1 ;
Capsella bursa-p. , 9 ; Lychnis vespertina. 1; Stellaria media, 10;
Geranium robertianum, 1 ; Ulex europceus, 17 ; Sarothamnus
ecoparius, 2 ; P otentilla fragariastrum, 7 ; Fragaria vesca, 5 ;
Anthriscus sylvestris, 1 ; Petasites fragrans, 19; Tussilago farfara, 2;
Beilis per ennis, 14 ; Senecio mdgaris, 16; Taraxacum offidncde, 7;
Linaria cymbalaria, 3 ; Veronica agrestis, 6 ; V. chamcedrys, 1 ;
I . serpyllifolia, 1 ; V. hederifolia, 2 ; Lamium purpureum, 9 ;
L. album, 2 ; L. amplexicaule, 1 ; Daphne laureola, 13 ; Primula
mdgaris, 10 ; Mercurialis perennis, 6 ; Corylus avellana, stam. and
pist. , 11 ; Ruscus aculeatus, 19.
Ryde, J anuary 2, 1S97. Henry H. Pollard.
*** The list given by Mr. Pollard will serve as a useful supplemc nt to that pub¬
lished last week.— [Ed. Pharm. Journ .]
Liquor Bismuthi.
Sir, — On two previous occasions you have permitted me to
discuss in your columns the precipitation of liquor bismuthi et
ammonise citratis by sodium bicarbonate. May I now say that this
reaction is inhibited by the presence of either mucilage of
tragacanth or of that made from Irish moss. With the intention
of obtaining a fine and easily suspended carbonate of bismuth in
the form of a lotion, I mixed 18 fluid ounces of the liquor bismuthi
with 480 grains of sodium bicarbonate, and 24 fluid ounces of
mucilage of Irish moss prepared as directed in the ‘ Art of
Dispensing,’ p. 168, adding also 1 fluid ounce liquor picis carbonis,
B.P. C. For six months the mixture has remained unaltered, with
no sign of milkiness or precipitation.
A small quantity mixed in the same proportion, but with dis¬
tilled water only, became milky in twelve hours, and deposited a
precipitate. With the addition of the coal tar solution the milki¬
ness was perceptibly retarded, and there was no actual precipita¬
tion in twenty-four hours. Freshly made mucilage of acacia was
next tried, and a decided turbidity was produced, but at the end
of twelve hours no sediment had fallen. The mucilage of
tragacanth in like quantity preserved the mixture quite limpid for
twenty hours. The interest of the observation lies in its reveal¬
ing the power which a simple mucilage possesses to hinder
chemical action. So that in addition to the strength of the
solutions used, the variations of temperature, exposure to light,
and other conditions, the presence of a mucilaginous' retarding
agent must be borne in mind in considering the phenomena of
precipitation. For dispensing purposes a clear mixture would
appear to be best insured by the judicious employment of
tragacanth mucilage.
Dover, January If, 1897. J. F. Brown.
Sol. Strontii Iodid. Paraf. Javal.
Sir, — In reply to “Pharmacist” in to-day’s Journal, I beg to
hand you the following : — •
V Strontii Iodid. (Paraf. Javal) . . 3iii.
Glycerini . . . . .. giss.
Aquam ad . Jvi.
M. (Filter).
I believe Paraf. J aval is the name of the chemist who worked up
the strontium salts. Such was my information the only time I
had occasion to order the salt, and I may say that I was advised
always to mention Paraf. Javal when ordering, as the ordinary salt
was not so good. Why, I can’t say.
Elgin, January 2, 1897. Alex. Robertson.
Chemists’ Federation.
Sir, — I regret that some action has not been taken to form the
chemists into one federation for defence or attack in regard to the
trade in proprietary articles. The P.A.T.A. is, in a sense, inviting
our trade to combine in helping our worst enemies, the proprietary
medicine men, the men who are gradually gripping us by the threat
and will make our business one simply to stock their goods and pass
over to the public at a minimum of profit. The American chemists
are in this pitiable condition, through the constant rush on the
market of new specialties. Before we get to that state let us stem
the tide (if not, we sink) and combine to hold the manufacture and
sale of proprietaries amongst ourselves.
Surely we can do as well as the poor working man with his
small wage and his grand example in the matter of trade unionism.
We might form one gigantic trust to boom the public with one
pill (worth 25s. per box), one emulsion, one Mother Humbug’s
syrup, etc., and reap a handsome profit out of the undertaking ;
supply shareholding chemists only (thereby gently leading into the
fold the non-unionists), prevent underselling, and drive the
medicine men, who are trying to sap our trade to its foundations,
out of existence.
It is not only in taxed medicines that we are handicapped, but
in what I may term the raw drug trade ; the public are now made
to require pepsin, rhubarb, quinine andiron, 1 drop doses of tinctures,
and a hundred other things in compressed form, and the nuisance
of it is that one section must have them prepared by Smith,
another by Brown, another by Jones, and we are supposed to stock
each make of each drug, or be out of the class of respectable
chemists where they can always be obtained ; this could be stopped
by a strong federation.
I could point out many other grievances which might be stopped
or greatly lessened. I should just like to give a little hint as to
the scheme of combination in proprietary articles, and its advan¬
tage from a monetary point of view. Say the average price charged
to us for the present advertised specialties is 9s. 6 d. per dozen for
the 13 \d. size, which costs 3s. 6d. per dozen, leaving 6s. for adver¬
tising and profit to the maker, and retailed at 10s., leaves a noble
6d. to us for selling. Compare! With our own adopted child we
should have less advertising (by not fighting one another), the cost
price would be less, and instead of the humble 6 d. per dozen we
should have nine times that amount.
The profits made by the federation would be used for dividends
and forcing the demand. Clarke was credited with making
£30,000 on the sale of blood mixture, and Holloway much more.
Why could not the federation, with hundreds and thousands of
willing hands to help, do better ? A movement of this description
is not put on foot without expense, and chemists must be prepared.
40
PHARMACEUTICAL JOURNAL,
[Jan. 9, 1897
to put down their shillings in order to ensure their pounds after¬
wards.
If chemists in any part of the kingdom are willing to join in
this movement and will communicate their willingness to me to
do so, and enclose stamps for replies, saying how much they would
be inclined to invest in £1 shares in a limited company (5000 are
wanted to make a big success), I will, if there is anything like
support, take steps to have the matter put in hand w'ithout delay.
A scheme of this kind must mean to many that their pet child
proprietary will be neglected, but let me point out that the
adopted one will become a far stronger support to them than their
own they reap as good a profit with the adopted one, and also
benefit by the sale of every one of such articles throughout the
federation.
48, Waterworks Street, Hull. G. R. Foulston.
January 4, 1897.
The Students’ Page.
Sir, On turning over the pages of the Journal, as I have been
wont to do from week to week for the past few years, my heart
filled with joy when I beheld the heading “ The Students’ Page.”
This comes to us students as a New Year’s gift of very great value.
It is proposed to publish from “time to time” articles or notes
which are intended to remove “ stumbling blocks.” Well, I am
sure the first students’ page has removed one great stumbling
block, viz., that of the “committing to memory the B.P.” I, along
with many others, have always been under the impression that
preparations of the B.P. had to be almost wholly committed to
memory. Have not the strengths of all the tinctures, infusions,
decoctions, etc., to be remembered ? [Refer to note again. — Ed Ph.
Journ.\ All students will be pleased to see a page of the Journal
devoted to their special interests. The innovation is certainly,
from the Minor student’s point of view, the best of all that has
taken place in the contents of the J ournal during the past year or
two. I thank you, sir, for this, and look forward with expecta¬
tion to the removal of other “stumbling blocks” at no distant
future, and hope there will be no more than seven days between
the “time to time.”
January 5, 1897. British Student (74/26).
ANSWERS TO QUERIES.
[ Queries addressed, to the “ Editorial Department, 17, Bloomsbury
Square, W.C.,” will be replied to in the Journal as early as possible
ajter receipt, but the Editor cannot undertake to reply to them
through the post, nor is it always possible to publish answers the same
week. Questions on different subjects should be written on separate slips
of paper, each of which should bear the sender’s name or initials.
Readers requiring working formulae for special preparations, and
intimating their wants to the Editor, will be assisted as far as may be
practicable. The word “parts,” when used in formulas, invariably
indicates parts by weight. Anonymous queries will be ignored .]
Moss Identified. — Your specimen is Fontinalis antipuretica.
[Reply to A. R. — 74/20.]
Novel Dispensing Balance. — Try Messrs. Maw, Son and
Thompson, or write direct to maker. [Reply to T. G.— 74/15.]
Lin. Pot. Iodid. c. Sapone (Unna).— See reply to F. J. Ellis in
Ph. J. for December 26. [Reply to M. P. S. — 74/6. ]
Blue Dye. -It is neither methylene blue nor Hoffmann’s blue
biit sodium triphenyl-rosaniline sulphate, known as alkali blue,
Nicholson’s blue, or fast blue, and contains a considerable amount
of sodium sulphate. [Reply to Associate.— 74/7.]
Manufacture of Limes. — We are informed that in making
these, cylindrical pieces are turned out of marble or limestone and
then burned, the marble cylinders yielding soft limes whilst the
limestone gives hard ones. [Reply to W. P.— 65/33.]
Phenyl-hydrazine. — You state the formula of this compound
correctly. Full information concerning it will be found in
M‘Gowan7s translation of Bernthsen’s ‘ Organic Chemistry ’
(Blackie, 7 s. Gd.), the handiest work of reference in this subject
for pharmacists. You can enjoy the use of the Society’s Library
by becoming a Registered Student. [Reply to S. H.— 74/19.]
Books on Ferns, etc. — (1) M. C. Cooke’s ‘Fern Book for
Everybody ’ (Warne and Co. ). (2) For practical work in the field
get Holmes’ ‘ Botanical Note Book’ and Shirley Hibberd’s ‘Wild
Flowers,’ or Grierson’s ‘ Lessons from Fields and Lanes ’ ; for
practical structural botany use Scott’s ‘Structural Botany’ (A. and
C. Black), and for the anatomy of plants, Bower’s ‘Practical Botany
for Beginners’ (Macmillan). [Reply to W. T. — 74/10.]
Discoloured Turpentine. — An iron cistern is not at all suitable
for storing turpentine. The best way to remove the colour from
your residual stock would be to have it redistilled. If you cannot
do this yourself, probably your wholesale house would do it for you.
You mighirremove a good deal of the colour by adding a pound or
two of commercial animal charcoal to the bulk, and filtering it.
through the same substance, but this is at the best a troublesome
and wasteful process. It could be “ re-drawn ” with much less
loss and trouble. — [Reply to H. G. A. — [73/17.]
Glycerin Jelly. — We doubt if you will find that agar jelly is
less viscid than the gelatin preparation. Possibly either a soap
basis or one of glycerin of starch will better meet your require¬
ments. The former may be made as follows : — Shred 1 ounce of
transparent soap, dissolve it in 4 fluid ounces of water and 4 ounces,
by weight of glycerin with the aid of heat. While hot add 20 ounces
by weight of glycerin, and when nearly cold perfume to the
desired odour and pour into the pots. The starch basis is made
from Tous les mois starch, 280 grains ; glycerin, 4 fluid ounces
water, 1 fluid ounce. Heat until transparent, and when nearly cold
perfume and pour out. [Reply to G. and K. — 73/8.]
Photographic Negatives. — Please always number your negatives
when sending for examination. Your specimens are being returned
numbered for convenience of reference. 1. Very much over¬
exposed and too strong a developer used ; would give a good print
if intensified with mercury and ammonia. 2. Fully exposed and
under-developed. 3. Ditto. 4. Slightly under-exposed and under¬
developed. You do not state what method of development yon
are using, and probably the developer is a little too strong in
alkali. The rich purple tone depends a great deal upon the
character of the negative ; it would be impossible to get it from
your negatives, as at present they are not plucky or vigorous
enough. [Reply to H. G. M. — 72/24.]
OBITUARY.
Bennett. — On November 11, John Henry Bennett, Chemist and
Druggist, of Cheltenham. Aged 47.
Roger, — On December 26, James Roger, Chemist and Druggist, df
Rhynie, Aberdeenshire. Aged 86.
PUBLICATIONS RECEIVED.
Anatomischer Atlas der Pharmacognosie und Nahrungs-
MITTELKUNDE, VON Dr. A. TSCHIRCH AND Dr. O. OeSTERLE.
Lieferung II. Pp. 30. With five plates. London : Williams and
Norgate, 14, Henrietta Street, Covent Garden. 1896.
Bacteriological Diagnosis. By St. George Reid, Bacterio¬
logist to the Central London Throat and Ear Hospital. Pp. 64,
Price 2s. 6 d. London : Bailliere, Tindall and Cox, 20 and 21,
King William Street, Strand. 1897. From the Publishers.
NEWSPAPEBS sent to the Editor should have the paragraphs
marked to which it is desired to call attention. Copies have
been received during the week of the following : — Norwood Weekly
Herald, The Morning Leafier, The Bristol Mercury, Scarborough
Evening News, The Daily Mail, The Arbroath Herald.
COMMUNICATIONS, LETTERS, etc., have been received from
Messrs. Austen, Barnett, Bottle, Breeze, Brown, Butler, Daves,
Duncan, Foulston, Grant, Hicks, Hogg, Holding, Holmes, Hudson,
Ingham, Jack, Jackson, Jarvis, Keen, Lescher, Linstead, Maggs,
McKellar, Parke, Payne, Peckolt, Pollard, Ridgwood, Roberts*,
Robertson, Shepherd, Squire, Taplin, Taylor, White-, WhysalL;
Jan. 16, 1897]
PHARMACEUTICAL JOURNAL.
4 L
HUMPHRY DAVY ; POET AND PHILOSOPHER.*
This life of one of the founders of modern chemistry, written by
so competent a pen, is a welcome addition to the admirable series
of lives of men of science now appearing, and the volume now
issued should be especially useful when so much attention is being
given to scientific education and so much — wise and otherwise —
written about English chemists.
The life of Davy comes appropriately between those of Dalton
and Faraday, though it must not be forgotten that their lives are not
in successive generations, but rather that they were'contemporaries.
Dalton was born in 1766, Davy twelve years later in 1778, and
Faraday thirteen years later in 1791. But while the brilliant life of
Davy was comprised in little more than fifty years, both Dalton and
Faraday long survived him.
Humphry Davy, like Dalton, was born of the yeoman class, and
also like him had a somewhat shiftless father, but a mother of
greater powers. In both cases too, although without position or
influence taaid their advance on the lower rungs of the ladder of
fame, they yet had the good fortune to meet with kind friends, who
were able to assist to a very great extent youthful self-education.
Nine years at the Penzance Grammar School, under the rule of
the Rev. Mr. Coryton, “ gave him nothing beyond a smattering of
elementary mathematics and a certain facility in turning Latin
into English verse.” The reverend master’s method seems to have
been the customary liberal application of the cane, supplemented
by a special habit of pulling the ears of the boys. On one occasion
we are told that Davy appeared before him with a large plaster on
each ear, explaining with a very grave face that he had “ put the
plasters on to prevent mortification.” Bat he had the advantage of
a kind and wise friend in Mr. Tonkin, who had been the adoptive
father of Mrs. Davy and her sisters, and extended his kindness to
her son Humphry. In his library the future chemist picked up for
himself most of what he obtained in the way of general knowledge.
The death of his father when he was sixteen years of age had a
great influence on his character, and as eldest son, “ he dried his
mother’s tears with the assurance that he would do all in his power
for his brothers and sisters,” a promise to which he adhered through
life.
He was fortunate again in making friends such as Gregory Watt,
the son of James Watt, the engineer, and Mr. Davies Gilbert, who
lived to succeed him in the presidential chair of the Royal Society.
These were no doubt attracted by his intelligence, and were able to
help him by the use of books, and still more by the influence of
trained minds.
One wonders whether youths of seventeen now prepare for them¬
selves such a programme of study as that set forth by Davy in the
opening pages of his earliest note-book, dated 1795 ? It comprises
twenty-six subjects, beginning with religion and ending with
mathematics, and including English and no less than six foreign
languages !
At this period he was fond of metaphysics, and we are told of an
argument with “ a worthy member of the Society of Friends, who
concluded with the remark, ‘ I tell thee what, Humphry, thou art
the most quibbling hand at a dispute I ever met with in my life.’
Whether it was in revenge for this sally that the young disputant
composed the ‘ Letter on the Pretended Inspiration of the Quakers,’
which is to be found in one of his early note-books, does not appear.”
Of the poetical side of his character little need be said here»
but it is clear that his powers were very considerable on no less
authority than that of Coleridge and Southey ; the former saying
* Humphry Davy; Poet and Philosopher. By T. E. Thorpe, LL.D.,
F.R.S. Pp. 240. Price 2s. 6d. London: Cassell and Co., Limited. 1896.
Vol. LYIII. (Fourth Series, Vol. IV.). No. 1386.
that “ if Davy had not been the first chemist, he would have been
the first poet of his age,” and the latter, “ Davy was a most extra¬
ordinary man ; he would have excelled in any department of art or
science to which he had directed the powers of his mind. He had
all the elements of a poet ; he only wanted the art. I have seen
some beautiful verses of his. When I went to Portugal I left Davy
to revise and publish my poem of ‘ Thalaba.’ ”
Of course he made early chemical experiments with the primitive
apparatus of “ phials, wine-glasses, teacups, tobacco pipes, with an
occasional earthen crucible,” and with the usual result of occasional
evil odours and explosions, to the alarm of his kind friends and
neighbours. The apparatus was primitive, but if youthful
enthusiasts of later days have better appliances, it is doubtful
whether they obtain better results or gain a better training.
When not quite twenty years of age, he made his first step
towards professional life, going as Superintendent of the
“Pneumatic Hospital,” established at Clifton by Dr. Beddoes, for
the investigation of “ the medicinal powers of factitious airs.” This,
appointment, although the schism of the hospital itself was a
failure, was of the utmost importance to Davy, for it gave him
opportunity for work, and he also by failure and by success in
publication had most useful training, which probably affected his
subsequent course. He published his first two papers here, the
first “ On Heat, Light, and the Combinations of Light, with a
New Theory of Respiration,” and the second “ On the Generation
of Phosoxygen (Oxygen Gas), and on the Causes of the Colours
of Organic Beings.” In the first of these he attacks Lavoisier's
doctrine that heat was a material substance, and that oxygen was
a compound body, composed of a simple substance combined with
the matter of heat, or caloric. He proceeds with youthful
confidence “ to demolish the French theory in half an hour.”
This adventure need not be followed, as Dr. Thorpe says “ Jupiter in
the shape of a Reviewer, soon hurled the adventurous boy from the
giddy heights to which he had soared .... and his theory was.
either mercilessly ridiculed or treated with contempt.” But the
lesson was useful, and his next publication “ On the Silex Com¬
posing the Epidermis or External Bark, and Contained in other
parts of Certain Vegetables,” gave proof of this. “ The theme was
humble enough, and the language as sober and sedate as that o£
Mr. Cavendish.” Besides this he did much work on gases, and
especially on the respiration of nitrous oxide. Much was expected
of the action of this and other gases in medicine, and if but little re¬
sulted in this respect, Davy did work which was good from a chemical
point of view, and courageous also, for he made his experiments on
his own person with, in one or two cases, almost fatal consequences.
Once he breathed “ water gas ” made by passing steam over char¬
coal, and was with difficulty brought back to consciousness. At-
this epoch Dr. Thorpe inserts some very interesting letters to Davy
from Southey and Coleridge, and one from “good old Dr. Priestley.”'
But he was not long at Clifton, and we are told of the steps which,
led him, at the age of twenty -two, to the scene of his chief and
triumphant labours, the Royal Institution, then newly founded,
where he was engaged in the first instance as “ Assistant Lecturer
in Chemistry, Director of the Laboratory, and Assistant Editor of
the Journals of the Institution ” at a salary of one hundred guineas
per annum, with room, coals, and candles.
He had now found a fitting and most congenial sphere of work.
At the very early age of twenty-two he was in possession of a
laboratory for his experiments, a lecture-room for public dis¬
courses and a receptive audience. His success as a lecturer waa
immediate and complete, and if the Institution was a splendid
opportunity for him, he was a no less opportune acquisition for the
Institution, for there seems to be little doubt that its original form.
42
PHARMACEU TICAL JOURNAL.
[Jan. 16, 1897
as designed by Count Rumford, would have been a failure, but in
Davy’s hands it took a different shape, and one which has proved to
be lasting. His lectures, with constant novelty from the results of
his own researches, and aided by his brilliant style and experi¬
ments, attracted large audiences of the most distinguished and
fashionable people of the metropolis. The success of the Institution
depended on him, and this was shown in 1808, when he was pros¬
trated by a serious illness. Dr. Thorpe writes, “ One proof of what
Davy was to the Royal Institution is seen in the position to which
it was reduced in consequence of his protracted illness.” The
lectures were postponed, and by their interruption “the
income of the Institution was greatly diminished; it fell from
£4141 in the preceding year to £1560. This was the low-water
mark of its financial state.” However, after a long illness, he
recovered, and resumed his work and his success. Space will not
allow us to speak more of his career here. The chapters on the
work done in laboratory and lecture room at the Institution are
most interesting. Two illustrations are given, one the well-known
caricature sketch of Gillray (judiciously curtailed) entitled “Pneu¬
matic Experiment at the Royal Institution,” and the other from a
drawing by Miss Moore showing the laboratory in Davy’s time.
No mention is made of the interesting meeting of Davy and
Dalton on the occasion of the latter coming to the Institution in
January, 1804, to deliver his first course of lectures. Davy had
then been installed there for three years, and Dalton speaks of him
as “ a very agreeable and intelligent young man, and we have inte¬
resting conversations in an evening. The principal failing in his
character is that he does not smoke.”
From the Royal Institution, where it may be said that Davy
attained the summit of his ambition in research, we are led to the
presidency of the Royal Society, where he reached his climax of
social rank. This is, unfortunately, scarcely so pleasant reading,
for here Davy’s defects of personal character are shown, and some¬
thing of the reasons of his later unpopularity. He was knighted on
April 8, 1812, and made a baronet in 1818. It is difficult to avoid
the impression that the brilliance of his success, with this added
distinction and the wealth which came to him by his marriage, had
a baleful influence, and that Sir Humphry Davy, Bart., was a less
estimable person than Humphry Davy the chemist.
There are two points, and those important ones, in which it is
difficult to agree with Dr. Thorpe. The first is in his estimate of
Davy’s genius, and the other in his judgment on the question of the
safety lamp. He says, and no doubt truly, that “at no period
of his life could he exercise that power of sustained and con¬
centrated thought which so strikingly characterised Newton or
Dalton or Faraday,” and yet later he says that “ in genius he
was unquestionably superior to Faraday.” But many will
question this latter opinion very strongly. The arguments that
“ what Davy was to Faraday, Faraday would have been the first
to admit,” and that “ Faraday was not easily roused to anger, but
nothing so effectually moved him as any aspersion on Davy’s
character as a man of science, or any insinuation of ungenerous
treatment of himself by Davy,” are quite beside the mark, for
no one could justly asperse Davy’s scientific character, even if com¬
paring it with that of Faraday, and, moreover, Faraday is not a fit
witness to call in such a question. No doubt the gentle and
chivalrous Faraday would, in spite of unkindness, yet strongly and
rightly too, defend his chief’s scientific repute.
In regard to the safety lamp question it is necessary to speak
with reserve, unless one has had the great advantage enjoyed by the
author of perusing the “ rare, if not unique, collection of pamphlets
and reprints of newspaper articles” in the possession of the
Literary and Philosophical Society of Newcastle-on-Tyne.
The claims of Stephenson are dismissed, however, in a somewhat
too summary fashion with the argument that “it is difficult to
imagine that an unlettered man, absolutely without knowledge of
physical science, could have discovered the philosophical principle
upon which the security of the lamp depends.” To begin with, the
question is not whether Stephenson discovered this philosophical
principle or not, but whether he made a safety lamp or not. It is
true he was then “ only an engine-wright,” but he was in a
responsible position, having charge of the machinery of a number
of collieries belonging to the “Grand Allies.” He was just three
years Davy’s j unior, and at that time some thirty-three years of age.
Of course he had far less knowledge of physical science, but can it
be said that he was “ an unlettered man, absolutely without know¬
ledge of physical science,” having regard to the fact that he and
his son Robert had access, through the kindness of the Rev. William
Turner, one of the secretaries of the Philosophical and Literary
Society of Newcastle, to the stores of books and instruments of that
valuable institution ? In ‘ Smiles’ Life ’ it is stated that George
Stephenson said of Mr. Turner that he “ was always ready to assist
me with books, with instruments, and with counsel gratuitously
and cheerfully. He gave me the most valuable assistance and
instruction, and to my dying day I can never forget the obligations
which I owe to my venerable friend.” It must not be forgotten
that the help thus gratefully acknowledged was given to a man
of most exceptional mental power, at perhaps the most active and
receptive time of life, and with marvellous mechanical ability.
Without charging Dr. Thorpe with sharing the feeling, possessed
by some men who call themselves scientific, of contempt for a mere
mechanic, it may be asked whether he has been influenced by
Dr. Paris, who in the heading to one of his chapters puts —
“The invention of the safety lamp, claimed by a Mr. Stephenson”
— and again in the body of his chapter puts these words which,
more suo, are grandiloquently expressed, but appear in sub¬
stance very similar to the above quoted words of Dr. Thorpe :
“It will hereafter be scarcely believed that an invention so
eminently philosophic, and which could never have been derived
but from the sterling treasury of science, should have been
claimed in behalf of an engine-wright of Killingworth, of the
name of Stephenson,” a person not even professing a knowledge of
the elements of chemistry.” It must, of course, be remembered,
that Dr. Paris wrote in 1830 or 1831, and although the “ person of the
name of Stephenson ” had ceased to be the engine wright of Killing-
worth, and had just carried the Liverpool and Manchester Railway
across Chat Moss, and had constructed the “Rocket” engine, yet
these achievements had perhaps not reached Dr. Paris’s ears. Per¬
haps the true version is that there is little doubt that Davy’s lamp
was constructed as a result of scientific research and with due
regard to scientific principle clearly ascertained and applied, while
Stephenson’s was constructed by successive trials, led by the same
principle, but far less accurately or clearly apprehended. There
can now be no question of Stephenson’s honesty in the matter, and
as Dr. Thorpe says, “ his behaviour throughout the whole f
the controversy increases one’s respect for him as a man of
integrity and rectitude.” The matter was fairly stated by Robert
Stephenson when asked about it in 1857. He said “ I am not exactly
the person to give an unbiassed opinion ; but, as you ask me frankly^
I will as frankly say that if George Stephenson had never lived, Sir
Humphry Davy could, and most probably would have invented the
safety lamp ; but again, if Sir Humphry Davy had never lived,
George Stephenson certainly would have invented the safety lamp>
as I believe he did, independent of all that Sir Humphry Davy had
ever done in the matter.”
It is apparently a case of independent discovery, honourable to
Jan. 16, 1897.]
PHARMACEUTICAL JOURNAL.
43
both inventors. Dr. Thorpe says in reference to comparisons between
Davy and Faraday, that “ it is not necessary to belittle Davy in
order to exalt Faraday,” and whilst thoroughly agreeing with this, it
may be added that it is not necessary to belittle Stephenson in order to
exalt Davy. In truth, men like Dalton, Davy, Faraday, and Stephen-
sod, are of the race of giants, head and shoulders above their
fellows, and it is useless to attempt to gauge their exact relative
intellectual stature with a foot-rule.
In conclusion, the sincere thanks which all chemists who read
this little book must feel should be expressed to Dr. Thorpe, for
thus giving, in the short compass of 240 pages, so lively and
interesting a portraiture of a great chemist who, in so few years
achieved such great and far-reaching results.
ON THE EFFECTS OF BEHRING’S ANTITOXIC SERUM IN
DIPHTHERIA.
Wesener (Munch. Med. Woch .) concludes his observations on this
subject by answering the questions raised by Hansemann and other
critics of the method.
Is the Serum Injurious ? — Almost every drug from mercury and
iodide of potassium to antipyrine and trional have been observed to
cause certain unpleasant after-effects, and in the same manner
cutaneous eruptions and pains in the limbs and effusions into joints
have been observed after the use of antitoxic serum, but there is no
evidence to show that any of these consequences are really of a
serious nature.
Although the great majority of observers have found that the
number of diphtheria patients who suffer from nephritis is not
greater with the serum treatment than it was before the method
came into use, Hansemann and Kassowitz believe that the serum
treatment causes albuminuria in a certain number of cases.
Wesener’s experience has led him to take the view of the majority.
Wesener found that out of ninety-five cases in which Loffier’s
bacillus was present albuminuria occurred in twenty-five, i.e., about
26 per cent., whilst in a consecutive series of 139 cases treated
before the serum method came into use albuminuria was observed
in thirty-eight cases, i.e., in 27 per cent. The course of the renal
complications was not less favourable in the cases treated with
serum than in those treated by the older methods. In thirty-one
instances, or about one-third of the ninety-five cases, skin eruptions
were observed during the treatment. In twenty-two cases the erup¬
tion resembled that of scarlet fever, and in these cases it became a
question whether the eruption was caused by the serum or was an
instance of what is sometimes observed, namely, a double infection
of diphtheria and scarlet fever. By attention to the form of the
eruption, the degree and duration of fever accompanying it, and
the presence or absence of desquamation, a positive diagnosis can
often be made, but there remain some doubtful cases which require
isolation as a precaution. Six out of the twenty-two cases
Wesener decided to be true scarlet fever, and not due to the serum.
Joint affections were observed in four of the cases, but they were
not of a serious nature.
Is the Serum a Curative Agent ? — This question cannot as yet be
answered definitely. Many times the injection of serum is followed
by a marked improvement in the condition of the patient, but
similar results have, though not so frequently, followed the older
methods of treatment.
Single cases reported to record a marked improvement following
on the exhibition of the serum should be received with caution ;
since the same thing is sometimes, if perhaps less often, seen when
the serum is not used. On one important point observers are almost
unanimous : the serum has an unmistakably definite effect in
diphtheria of the larynx, trachea, and bronchi. Thus, after the I
injection of serum the number of cases in which diphtheria extends
from the fauces to the larynx is diminished, and cases in which the
larynx is already attacked when the serum is injected show a
diminution in the number in which tracheotomy becomes necessary,
and lastly, the percentage of recoveries after tracheotomy is
distinctly higher when the serum is used. These are most weighty
considerations, and if they should be upheld, fully indicate the
claim of the method to a place in the first rank of therapeutic
measures. The results of Wesener’s cases are in accord with this
general experience.
The serum treatment cannot be claimed as a preventive measure
against the dreaded complications of diphtheria, eg., nephritis,
pneumonia, paralysis, and inflammation of glands. Examples of all
these occurred in the series of cases.
Does the Treatment confer Immunity ? — In no case of this series
was the serum used as a prophylactic merely, but three patients after
admission to the hospital and injection with serum, were found to
be suffering from pseudo-diphtheria : that is to say, bacteriological
examination proved the absence of Loffier’s bacillus. In none of
these cases was the disease contracted, in spite of an exposure to
infection of several days’ duration. The beneficial effect of the
serum treatment may be reasonably regarded as evidence of a local
immunisation, and it is important to note that in Wesener’s cases
the serum treatment was employed without the addition of local
treatment, for the reason that in children the struggling and scream¬
ing caused by attempts at local treatment result in the inhalation
of particles of membrane and discharge, and expose the patient to
the danger of infection of the bronchi and the lungs. This “ local
immunity ” is all that can be claimed for the remedy in this
direction. No immunity is conferred on the tissues of the body
generally, as is shown by the fact that in three of the tracheotomy
cases treated with serum, infection of the wound occurred, and,
further, in three cases second attacks of the disease were noticed
In the intervals between the first and second attacks-
the patients suffered from other diseases— scarlet fever in
two cases, and pneumonia, with doubtful scarlet fever, in the third.
It is suggested that the intercurrent diseases may have diminished
what immunising influence the serum may have had. The author
concludes a temperate and most valuable article by enunciating the
following conclusions : —
1. In simple diphtheria of the fauces the serum treatment tends
to prevent extension to the larynx, but otherwise effects neither
more nor less than thorough local treatment.
2. In diphtheria of the larynx serum treatment appears to obviate
the necessity for tracheotomy in some cases.
3. In diphtheria of the larynx the serum is the best preventive
agent against extension of the disease to the trachea and
bronchi. If the trachea and bronchi are already affected the
serum treatment is of doubtful value.
4. Against septic processes present when the serum treatment is
applied, it is of less avail than ordinary local measures.
5. The immunising capacity of the serum has not yet been proved
to exist.
6. The serum treatment is not injurious.
Urtica Urens as a Haemostatic. — Under the name of
“ Poudre de Marr,” the powdered extract obtained by extracting the
fresh leaves and stems of Urtica urens with alcohol, and evaporat¬
ing to dryness, has a reputation as a haemostatic. Solovieff has
employed this substance in several surgical cases and in minor
operations, in all cases with satisfactory results. Since it seems to
be without action on organic tissues, it should prove a useful
haemostatic in all plastic operations. — Rev. de Thdrap. Med.-Chirurg.,
lxiii., 604.
44
PH ARM ACEUTIC AL JOURNAL.
UTICAL SOCIETY
OF THE COUNCIL.
Y, JANUARY 13, 1897.
Present :
Mb. Walter Hills, President.
Messrs. Allen, Atkins, Bateson, Bottle, Carteighe, Corder,
Grose, Hampson, Martindale, Newsholme, Park, Savory, Southall,
-Symes, and Young.
In the absence of the Vice-President, the Vice-Chair was
occupied by the Treasurer.
The minutes of the last meeting having been read and confirmed,
The President, after mentioning the receipt of letters from the
examiners acknowledging the vote of thanks passed at the last
meeting, said he had no doubt all his colleagues had seen with
great satisfaction that a distinguished honorary member of the
Society, Sir Joseph Lister, figured in the list of New Year
honours, he having been raised to the peerage under the title
of Lord Lister. He had sent him an official card of congratula¬
tion, to which he had received a suitable reply. They would all
wish him many years of health and happiness, and further
usefulness to humanity.
#
The Late G. F. Schacht.
The President then said : Since our last meeting one of our
leaders has fallen, and a distinguished and honourable
pharmacist has been called to his rest. With very little warn¬
ing death has closed the earthly career of George Fred¬
erick Schacht, who only a few months ago resigned a
seat on this Council, of which he had been for nearly twenty-five
years a highly esteemed member. You will all remember that
■early last year we received a letter from Mr. Schacht, asking us to
accept his resignation, and at that time a resolution was passed
eonveying the cordial thanks of this Council to Mr. Schacht for
his past labour, and expressing the deep affection and regard we
all had for him. But our late colleague inspired affec¬
tion as well as respect. He was not only an honour¬
able and high-minded man, but also a very loveable one.
To many of us he perhaps represented more nearly the ideal
pharmacist than anyone else. Distinguished in presence, courteous
in manner, absolutely honest in word and deed, enthusiastic in the
promotion of pharmaceutical education, and of everything
tending to the advancement of his calling, interested in the
progress of science generally, G. F. Schacht held a unique
position, and he has left a record which will long live in
the memory of those who had the honour of his friendship.
In many respects he was in advance of his time, and he was, I
think, sometimes a little disappointed that his proposals were not
more readily adopted. Those views were almost invariably such
as commended themselves in the abstract to his colleagues, and
only on the ground of practical expediency were they not gener¬
ally accepted. But Schacht ever kept a high ideal before him, and
his motto being principle, not expediency, the good seed which he
has sown will in due course spring up and bear good fruit.
He has laboured, and others will enter into his labours. It has
been said that “ gentleness, when it weds with manhood, makes a
-man.” According to this definition, G. F. Schacht was indeed a
man. Up to the last he maintained a youthful enthusiasm, to¬
gether with those personal charms of gentleness and thoughtful¬
ness for others, and I am glad to know that on the last day of his
life, Christmas Day, he was the bright and cheerful centre of a
happy family gathering. I beg, then, to move the follow¬
ing resolution, which will be seconded by the Treasurer, but before
doing so I may say that I have received letters from the Vice-
President and from other members of the Council expressing their
warm and affectionate regard for the late Mr. Schacht. I move —
“ That this Council desires to record its sense of profound regret at the death
of George Frederick Schacht, whose personality was regarded with respect
and affection by each of his colleagues, and the memory of whose wise and
[Jan. 16, 1897
untiring labours in the best interests of pharmacy will not readily die
amongst those who were associated with him. The Council tenders its
siLcere sympathy with Mrs. Schacht and her family in the irreparable loss
they have sustained.”
Mr. Hampson said he should only add a few words in seconding
this resolution. It was extremely difficult to control one’s feelings
on such an occasion, when they all remembered how recently their
friend had sat at that table. The loss of a good man, a strong
man, and- a man of principle was always a loss to the community,
he might even say to the country, and if they could not exactly
appreciate the loss of Mr. Schacht to the general community, they
must all feel how great was the loss sustained by the community
of pharmacy. They all knew him as a man of considerable
powers, always genial, always consistent, always faithful to his
convictions, which were invariably broad and high-minded. The
great grief of his family must be uppermost in their thoughts, and
they all sympathised with them.
Mr. Savory desired to add a few words to the very graceful
tribute which had been paid to the memory of Mr. Schacht, whose
death must be deplored by pharmacists all over the kingdom.
It was not his privilege to sit very long at that table in company
with Mr. Schacht, but he had the pleasure of knowing him very
intimately in private life. In the first place Mr. Schacht’s connec¬
tion with his (Mr. Savory’s) grandfather and family formed a great
bond of union, and he gratefully remembered the great interest he
took in his welfare. It was not until his student days in Bath
that he first made Mr. Schacht’s acquaintance, when his kindness
to him was indescribable. Since then he had known him more
intimately, another bond of union being a companionship in the
sport of fishing. It would be impossible to have a more genial or
kindly companion. His marvellous youth for his years struck
everyone with whom he. came in contact, as well as his great
intelligence and conversational powers. He should always regard
it a great honour to have known him.
Mr. Southall said he also had much pleasure in supporting
the resolution.
Mr. Atkins said he could not help endeavouring to express some
portion of what he felt on this occasion. He met Mr. Schacht first at
one of the early meetings of the Pharmaceutical Conference, when
he was immensely struck with his personality, and that ac¬
quaintance, having been renewed from time to time on similar
occasions, speedily ripened into an intense friendship, and
he should always feel that his connection with the Society,
if it had brought him no other boon than the personal
friendship of George Frederick Schacht, had abundantly repaid
for his association with it. It was a wonderful thing how deeply
some men etched themselves on the hearts and memory of those
with whom they came in contact ; it was that wonderful thing
called character, which was built up of many elements. The
President had most happily referred to the salient points, but
he might say that he was always impressed with Mr.
Schacht’s intense honesty, and next with the kindness
and courtesy with which (though often in a minority) he fought
out and argued his views. He was not only a good scientific
chemist, but a most accomplished pharmacist, and independently
of that he was a man of the widest culture. He even cultivated
the spirit of poetry, and he remembered his sending him a few
years ago some lines he had written with a request for his opinion.
This revealed a side of his character which was not previously
known to him.
Mr. Bottle said on this occasion he felt that he must endorse
the testimony which had been made to the character of the late
Mr. Schacht. He thought he might claim to be one of his oldest
friends. It had been his privilege during the time that he nad
known him to cultivate the closest friendship with him, and always
looked upon him as a typical pharmacist who was perhaps some¬
times somewhat in advance of his time. From time to time he
(Mr. Bottle) was not in accord with Mr. Schacht’s views, but his
difference with him was only on matters of principle. Mr. Schacht
at all times advocated views which he pressed so strongly and in a
way which could not do otherwise than gain the admiration of his
friends on the Council.
Mr. Symes thoroughly endorsed all that had been said on this
matter. He had sat for many years on the Council with the late
Mr. Schacht, and was always struck with his strong personality
and logical arguments. Many of the members could not always go
so far as Mr. Schacht went, but the extreme courtesy and graceful
manner in which he treated those who Offered from him made
them regret having to do so. Thai was a feature in the late Mr.
Jan. 16, 1897J
PHARMACEUTICAL JOURNAL
45
Schacht which endeared him to all. They all felt that Mr.
Schacht was a thorough man and a gentleman, and all deeply re¬
gretted his loss.
The resolution was then put, and carried unanimously.
The Board of Examiners.
The President said the usual official letter had been received from
the Privy Council Office approving the appointment of the Ex¬
aminers for 1897.
Diplomas.
The undermentioned, being duly registered as pharmaceutical
chemists, were respectively granted a diploma stamped with the
seal of the Society : —
Bowden, Harold.
Brigham, Edwin Beal.
Brown, Charles.
Campkin, Francis Sidney.
Critchley, Charles Albert.
Dann, Charles.
Goode, Arthur Frederick.
Pitcher,
Greenhahh, Edmund Parkinson.
Knight, William Arthur.
Last, Geo. Valentine Chapman.
Lloyd, Hugh William.
Masterman, Henry.
Morrell, John George.
Pearson, George Ernest,
s Frederick.
Election of Members.
The following, having passed the Major examination and
tendered their subscriptions for the current year, were elected
‘ ‘ Members ” of the Society : —
Critchley, Charles Albert ; Blackburn.
Dixon, Rowland ; Sheffield.
Dyson, Thomas Hatfield ; London.
Johnson, John Richard ; Plymouth.
Jones, William Miall ; London.
Last, George Valentine 0. ; LiverpooL
Latham, Hugh ; London.
Masterman, Henry ; London.
Moorhouse, Joseph William; Sheffield.
Morrell, John G. ; Stockton-on Tees.
Pearson, George Ernest ; Canonbui y.
Pitcher, James F. ; Princes Risboro’.
The following, who was in business before August 1, 1868,
having tendered his subscription for the current year, was elected
a Member of the Society : —
Glover, John Smith; Vancouver.
Election of Associates in Business.
The following, having passed the Minor examination, being in
business on their own account, and having tendered their subscrip¬
tions for the current year, were elected “Associates in Business ” of
the Society
Beal, Johnson ; Manchester.
Beckett, Harry Rumbold ; Tonbridge.
Burch, Thomas William ; Prestwich.
Close, Thomas ; Middleshro’.
Connan, Campbell Allan ; Cowdenbeath.
Cooper, George Henry ; Failswoith.
Crofts, Robart ; Canterbury.
Davidson, James Bruce ; London.
Hanson, Arthur William ; London.
Hunter, Robert ; Perth.
J ones, Robert Coetmor ; Bethesda.
Knowles, William Edward ; Birstall.
Mennie, James ; Golspie.
Mercer, Frederick Peter ; Wigan.
Paterson, Andrew John Kidd; Dundee.
Robinson, John James ; Carlisle.
Shaw, William Alfred ; Birmingham.
Stevenson, George Miller ; Cheshunt.
Stuttard, Thomas ; Colne.
Taylor, Abraham, jun. ; Morley.
Thompson, Herbrrt ; Manchester.
Wilson, James; Gt. Harwocd.
Nuttall, Maurice William ; Alfreton.
Priestman, William ; Penrith.
Rattray, David Smith ; Aberdeen.
Reed, Joseph; Dumfries.
Rtmmington, Whitworth ; London.
Robinson, Percy ; Norwich.
Rowland, George H. C. ; Matlock Bath.
Si ve wright, James ; Aberdeen.
Stewart, William Napier ; Glasgow.
Suttie, Joseph H. C. ; Broughty Ferry.
Wainwright, Percy; Crstleford.
Walker, George B ; Wellingborough.
Watt, Marshall Keith ; Dinecht.
Wheeler, Alice Maud ; Oxford.
Whitelam, John Herbert ; Hull.
Election of Students.
The following, having passed the “First” examination and
tendered their subscriptions for the current year, were elected
“ Students ” of the Society : —
Bailey, Daniel Jennings ; Denton.
Bailey, George W. ; Spalding.
Barley, Maurice Arthur H. ; Tunstall.
Barton, Harold ; Southport.
Battle, Ernest W. 0. ; Manchester.
Beeny, Wallace Frederick ; London.
Bell, William W. ; Newcastle-on-Tyne.
Billings, Sydney James ; Cheltenham.
Blair, William John ; Greenock.
Blake, Ernest A. ; Leighton Buzzard.
Burn, Mordey ; Manchester.
Chandler, Richard Walter ; Bristol.
Coley, Ernest James William ; Stroud.
Cook, Charles Henry ; Horsell.
Cooke, Robert Burt ; Newhaven.
Cooling, William Arthur : Newark.
Cooper, Herbert Edward ; Kettering.
Cottle, Charles James ; Newferry.
Dearden, Theodore E.; Luddenden Foot.
Deed, Arthur Edgar ; Lincoln.
Doughty, John Edward ; Birmingham.
Draper, Eliza Frances ; London.
Drynan, John Forgie ; Carluke.
Eggett, Louis C. ; Burnham-on-Crouch.
Evans, John Owen ; Chapeltown.
Excelby, George Henry ; York.
Ferriday, Herbert John ; Shrewsbury.
Fox, Thomas James ; Portsmouth.
Francis, Alan ; London.
Gale, William Edward ; Ilkley.
Goodyer, William; West n.
Gray, Alexander; London.
Greatrex, E J. Me William; Liverpool.
Greaves, Henry Eldred ; Ironville.
Green, Charles Orton : B ackley.
Hadfield, Sidney Herbert ; Preston.
Helliwell, Hubert Wellesley ; Bradford.
Henderson, Henry John ; Lowestoft.
Homer, Ernest ; Birmingham.
Horniblow, Kate Nellie ; Charlbu-y.
Irving, Lottie ; Muthill.
Jackson, Frederick harles ; Southport.
Jasper, William; Plymouth.
Jeffs, Richard Thomas ; Gloucester.
Jolly, William Isaac ; Bradford.
Kent, Frank Stephen ; Hastings.
Kerruish, Thomas Maltby ; Douglas.
Le Dain, Nicholas John F. ; Jersey.
Lindsay, Andrew ; Helensburgh.
Lister, Frederick Spencer; Cambridge.
Lycett, Herbert ; Workington.
Macadie, William, East Watten.
McFadden, William James ; Southsea.
McGhie, John Knowles ; Liverpool.
McRostie, James ; Stranraer.
Matson, Joseph ; Stockton-on-Tees.
Mellor, William Gilbert ; Warwick.
Morgan, Harold Marston ; Illesthorpe.
Morgan, Howell ; Twickenham.
Morris, Gabriel ; Winchmore Hill.
Morris, Kenneth Austen ; Presteigne.
Morris, Robert Leitch ; Dunfermline.
Nethercoat, Ernest Tom ; Ely.
Oldham, John Joseph ; Preston.
Oliver, John; Holywell.
Peek, John Wicliffe ; Clapham.
Peters, William Harold ; Breaston.
Pick, Frank Phillips ; Barnsley.
Plumb, Alfred ; Cambridge.
Porter, Frank ; Leicester.
Pugh, John James Edgar ; Leominster.
Purnell, Austin ; Clevedon.
Renouf, Lucy; Jersey.
Renouf, Nora ; Jersey.
Rosenloecher, Arthur R. ; Dalston.
Saunders, John ; West Worthing.
Shelley, George ; Bilston.
Steward, Charles Alfred ; Worcester.
Street, Spencer ; Littleport.
Tebbutt, Thomas P. ; New Brighton.
Thomas, Arthur G. ; Barrow-iu-Fumess.
Thomas, William Isaac ; Abergele.
Ullett, Frank ; Ilminster.
Walmsley, James Edgar ; Halifax.
Watson, Herbert Shepley ; Towcester.
Weddle, William Gardner ; Liverpool.
Webster, Bertram ; Uttoxeter.
Whysall, Edward Searson ; Grantham.
Willey, Francis Joseph ; Hoyland.
Willis, Alfred James ; New Brompton
Wise, Guy William ; Watford.
Election of Associates.
The following having passed the Minor examination, and
tendered, or paid as “Students,” their subscriptions for the
current year, were elected “Associates ” of the Society
Allen, William John ; Cardiff.
Burgin, Mark Frederick ; Kennington.
Cleave, Thomas William ; Leeds.
Courtenay, Edward ; Shrewsbury.
Devereux, Arthur E. ; Stoke-on-Trent
Dixon, William ; Kendal.
Deuth waite, Douglas George ; Ruaton.
Ellis, Frederic Richard ; Liverpool.
Evans, David ; Carmarthen.
Everett, Henry Percy ; Ipswich.
Fairley, Charles Ernest ; Sunderland.
Fletcher, Richard Bewley ; Sunderland.
Gibson, Hubert ; Leeds.
Glover, Charles C. ; Ashby-de-la-Zouch.
Gregory, Herbert William ; Lincoln.
Griffiths, Frederick Gray ; Manchester.
Haigh, William ; Stocksbridge.
Henderson, William ; Dollar.
Hopkins, John S. ; Stow-on-the-Wold.
Keif, Henry David ; Reading.
Lincoln, John Edward ; London.
Monaghan, John Edward ; Glasgow.
Morton, Henry Rosser ; Margate.
Murdoch, James ; Glasgow.
Myers, Gabriel ; Brough.
Norton, Alfred James ; Swansea.
Restoration to Register.
The name of the following person, who had made the required
declarations, and paid the restoration fee, was restored to the
Register of Chemists and Druggists ; —
Henry Little, 134, Jamaica Road, London, S.E.
Several persons were restored to their former status in the
Society upon payment of the current year’s subscription and a
nominal restoration fee of one shilling.
Mr. Bateson in connection with the election of associates and
students, drew attention to the prevalent feeling throughout the
country in favour of improved education, and the importance of
young chemists taking advantage of the opportunities which were
now offered in so many localities for continuing their educa¬
tion after they left school. A special move had recently
been made in his own small town, and evening classes
46
PHARMACEUTICAL JOURNAL.
[Jan. 16, 18W
were formed in connection with the Science and Art Department, a
registered chemist and druggist who had recently passed his
examination being the teacher of one of the science classes, whilst
a local doctor took a class in physiology. He thought if young
men would continue their studies after they had passed the Pre¬
liminary they would have a better chance of ultimately passing
the qualifying examination.
The President said there was no doubt that education was “ in
the air,” and it was very desirable that young pharmacists should,
if possible, be ahead of everyone else.
Report oe Finance Committee.
The Secretary read the report of this Committee, which was of
the usual character, and recommended various accounts for payment.
The President (as Chairman of the Committee) moved the
adoption of the report, and said there was nothing which
needed special notice in connection with the General Fund,
the payments, though somewhat large, being of the ordinary
kind, and including expenses connected with the examinations
and the School, tin connection with the Benevolent Fund he
was pleased to be able to report that in response to the
announcement made in December that money was needed for the
payment of annuities, several subscriptions had been received.
Amongst them were five guineas from the students of the Society’s
School, and four guineas from the Metropolitan School of Phar¬
macy, which showed that the younger pharmacists took an interest
in the Fund. Contributions had also been received from several
well-known firms, and from local and divisional secretaries, who
had been good enough to make a special Christmas canvass. He
was also glad to report donations to the Fund from Mr. Percy Nott,
local secretary for Bolton, five guineas ; from the Rochdale
Chemists’ Association, eight guineas ; and from Mr. J. Heron,
Edinburgh, ten guineas. The Camwal directors had sent £50 with
the following letter : — •
83, Qt. Russell Street,
Bloomsbury, W.C.,
Jan. G, 1897.
R. Bremridge, Esq.
Dear Sir, — At the last General Meeting of “ Camwal ” the sum of £50 was
voted to the Directors ; we now beg of you to accept that sum on behalf of the
Benevolent Fund of the Pharmaceutical Society, and at the same time we tender
to the Society our best thanks for its able administration of the Fund. We
consider it a boon that chemists are able, through your agency, to assist the
poorer members of the craft without running the risk of being imposed upon,
and without any deduction being made from the amount donated.
We are,
Yours faithfully,
The “ Camwal ” Directors,
per Horace Davenport,
Chairman.
All these generally were entitled to the thanks of the Council.
There was also a legacy of £9 from the estate of Ann Spenceley,
being the amount of the legacy, less duty, left by that lady some
few years ago. She was the sister of a chemist and druggist who
died many years ago, and the claims of the Benevolent Fund
were brought to her attention by a member of the Society.
The report and recommendations were unanimously adopted.
Report of Benevolent Fund Committee.
The report of this Committee included a recommendation of
grants to the amount of £76 in the following cases : —
The widow of a registered chemist and druggist (aged 63) who had a grant last
year, and is in bad health. London.
The widow (aged 87) of a registered chemist and druggist, who was an annui¬
tant, and died in November last. Ramsgate.
The widow (aged 70) of a pharmaceutical chemist member. London.
The widow (aged 67) of a pharmaceutical chemist member and subscriber, who
has had six previous grants. Doncaster.
A pharmaceutical chemist member, 1853-95 (aged 70), who has had two pre¬
vious grants, and was an unsuccessful candidate at the late election. Barry.
A registered chemist and druggist (aged 50) suffering from severe and
incurable disease. London.
Two other cases were not entertained, and another was deferred for further
information.
The Secretary reported the death on December 9 of J. 8. Jarvis (aged 57), who
had been an annuitant since 1892.
The Committee recommended that a public dinner in aid of the Benevolent
Fund be held in May next, and that the Council take the necessary steps to
promote the same.
Mr. Bottle (as Cbairman of the Committee) moved the adoption
of the report. He said it did not present any particular feature to
comment on. There had been half a dozen applicants who
had been relieved to the best of their ability. With regard to
the unsuccessful applicants, he hoped that they would be more fortu¬
nate another time.
Mr. Atkins, in seconding the adoption of the report, said he
would not add anything to what Mr. Bottle had said, but just
wished to call the attention of the Council to an effort that was
being made to secure the election of a child to the Infant Orphan
Asylum at Wanstead. Last month the Vice-President had directed
attention to an effort that was being made to secure the election
of another child of the same family to the London Orphan Asylum
at Watford, with what result was not yet known. He (Mr. Atkins)
would very earnestly submit the present case to the Council, and
through the Press to their brethren outside. The circum¬
stances were that a Mr. Robert Kirkby, a pharma¬
ceutical chemist at Ramsbury, Wiltshire, had died. The
widow was making a gallant effort to support herself in the
neighbourhood of London. The child on whose behalf he now
appealed was Robert Kirkby, aged 5J years. It was a most worthy
case, and he would do his best, and hoped his friends would do
the same, to secure the election of this child to the Infant Orphan
Asylum, at Wanstead. He did not think there was any form of
benevolence that was more helpful than to secure the election of
children to orphan asylums.
The President said he had no doubt the Press would make the
case known. He would only express his regret that the orphans
in question were not eligible for the Society’s Orphan Fund. It
was to be regretted that through inadvertence their parent had
not seen his way to subscribe for three years to the Benevolent
Fund.
The report was passed unanimously. Mr. Hampson said it had
been the custom to have a dinner every ten years, the object
being to make a grand effort at a time when perhaps the heart
was more open to augment the Benevolent Fund. By the Report
of the Benevolent Fund Committee, it appears that this year was
the right time to make the effort, and he trusted that it might be
very successful. He would just like to say that he hoped the
special Christmas effort would become a permanent contribution
to the Benevolent Fund. He concluded by proposing —
“ That the following he appointed a committee to arrange and carry out the
details of the decennial dinner in connection with the Benevolent Fund
the President, the Vice-President, the Treasurer and the members of the
Benevolent Fund Committee, and the London members of Council.”
Mr. Atkins seconded the resolution. It was a most worthy
cause, and he hoped would be a great successs.
Mr. Allen asked if he rightly understood the President to
intimate that if the parent of the children in question had sub¬
scribed for three years to the Benevolent Fund there were funds
at their disposal which would have helped those children.
The President said that was so.
Mr. Allen said that this was a point which should be urged on
the non-subscribers of the Benevolent Fund all through the
country.
The President, in putting the resolution, said he would just call
attention to the fact that this was the sixtieth year of the reign of
Her Most Gracious Majesty the Queen, and he hoped that there
would be this year of all years a very successful dinner in every
respect, and that by its means a large addition might be made to the
Benevolent Fund. He would also mention that it had been
arranged that this particular dinner should be held in place of the
ordinary annual dinner.
The resolution was passed unanimously.
Diplomas of Deceased Members.
Mr. Bottle asked if it was the custom to look after the
diplomas of deceased members. It occurred to him that after
the death of a member the diploma was valueless to his heirs and
executors, but that it would be available to anybody who had a
mind to make improper use of it.
The Secretary said they could not always be got, as they were
often lost.
Mr. Bottle said that was a misfortune, as they might often be
used improperly.
Jan. 16, 1807.]
PHARMACEUTICAL JOURNAL.
47
Mr. Bateson thought it only right and proper that the Society
should have the diplomas.
The President understood that it was the rule of the office to
write on every occasion asking for the return of the stamped
diplomas, but that in very many cases they could not be found.
Library, Museum, School, and House Committee.
Library.
The report of the Librarian had been received, including the
following particulars —
Attendance. Total. Highest. Lowest. Average.
November /Day . 390 26 9 16
Novemoer . \ Evening . 127 17 1 6
Circulation of Books. Total. Town. Country. Carriage paid.
November . . . 206 110 96 £1 7s. lid.
Donations to the Library had been announced {Pharm, Journ.,
December 12, p. 511), and the Committee had directed that the
usual letters of thanks be sent to the respective donors.
The Committee had recommended that the undermentioned
books be purchased : —
For the Library in London : —
Peters, Pictorial History of Ancient Pharmacy, 1889.
Guareschi, Einffihrung in das Studium der Alkaloide, 1896.
Yeo, Pood in Health and Disease, latest edition.
Tilden, Introduction to Chemical Philosophy, latest edition.
For the Library in Edinburgh : —
Tilden, Introduction to Chemical Philosophy.
The Scottish Medical and Surgical Journal, for one year.
Museum.
The Curator’s report had been received, and included the fol¬
lowing particulars : — •
Attendance. Total. Highest. Lowest. Average.
November /Day . 476 30 13 19
CNovemDer . \ Evening . 49 22 1 2
Several donations had been received {Pharm. Journ., Decem¬
ber 12, p. 511), and the Committee had directed that the usual
letters of thanks be sent to the respective donors.
A letter of thanks for duplicate specimens had been received
from Professor W. H. de Wytt, M.B., etc., Lecturer on Materia
Medica at St. Andrews University, N.B.
The President moved that the report and recommendations of
the Committee be received and adopted. There was really nothing
to call attention to, the recommendations being of a purely formal
character.
Mr. Symes drew attention to the very small average attendance
in the Library during the evening. One would expect the
attendance in the evening would be better than during the day,
but it seemed to be very much less.
The resolution was unanimously agreed to.
Local Secretaries.
Mr. John Harvey was appointed Local Secretary for Airdrie,
Mr. A. C. Cobb was appointed Local Secretary for Maidstone, in
the place of Mr. Stonham, deceased.
Report of Examinations.
January , 1897.
The following report on the examinations was presented : —
Candidates.
/ - X
Examined. Passed. Failed.
England and Wales. —
Major . 35 15 20
Minor . 196 63 133
Scotland. —
Major . 1 0 1
Minor . 140 48 92
Twenty-one certificates by approved examining bodies were
received in lieu of the Society’s “ First ” examination.
Pharmacy in Quebec.
The President read a letter which had been received from the
Pharmaceutical Association of the Province of Quebec, requesting
that the Council would take into consideration the question of re¬
ciprocity in British and Colonial certificates in pharmacy. It
stated that persons holding the diploma of the Pharmaceutical
Society of Great Britain who came to Quebec were admitted with¬
out further examination, and suggested that a reciprocal courtesy
should be extended to gentlemen who had passed their examina¬
tion in Quebec on going to England. Particulars of the examina¬
tions were enclosed. It was interesting to know of the good work
being done by the Pharmaceutical Association of the Province of
Quebec, but the only answer which could be made to the letter
was that whatever might be the views of the Council, it had no
power under the Act of Parliament to receive the certificates re¬
ferred to. A new Act would be required before the desired recip¬
rocity could be accorded.
General Purposes Committee.
This report, which dealt exclusively with legal matters, was
taken as usual in committee. It included a letter from the solicitor
as to the progress of cases which had been placed in his hands.
On resuming the report and recommendations were received and
adopted, and special resolutions were passed, authorising the
Registrar to institute proceedings against the persons named in
the resolution.
EXAMINATIONS IN LONDON.
January, 1897.
MINOR EXAMINATION.
Candidates examined . 19S
,, failed . 133
„ passed . 63
Allen, William John.
Anderson, Frank.
Bills, Albert James.
Burgin, Mark Frederick.
Chaundy, John Henry.
Craft, Charles.
Crawhall, Thomas Currah.
Orookham, Harry.
Curtis, Edgar.
Davies, Henry.
Devereux, Arthur Edward.
Dix, Henry Walter.
Dixon, William.
Douthwaite, Douglas George.
Edwards, Thomas Christ re as.
Elkington, Charles John.
Fletcher, Bichard Bewley.
Ford, Jessie
Fynn, Robert Hudson.
Glover, Charles Craft*.
Goodall, Frederic Charles.
Green, George Winfield.
Gregory, Herbert William.
Haigh, William.
Hankinson, Herbert Stanley.
Harman, Harry.
Harries, Wm. Geo. Augustus.
Hawker, William Harrifred.
Hoare, William Harold.
Horsfield, Jessie Agnes.
Huck, Henry.
J ean, Ei nest Albert.
John, Ernest.
Johnson, Robert Clitherow.
Jones, Robert Frederick.
Jones, Sidney Clifford.
Kent, Charles.
Leech, Peter.
Lincoln, John Edward.
Lloyd, Thomas Mainwaring.
Maynard, George Henry.
Moody, Thomas Adam.
Morton, Henry Rosser.
Nutiall, Maurice William.
Oatley, Thomas James.
Orme, Arthur J ohn.
Pattison, Herbert George.
Pickering, William Cowper.
Priestman, William.
Pr.nce, John.
Proctor, Ernest Anthony.
Reed, Joseph.
Richardson, Richard Conway.
Robinson, Percy.
Sadleir, Horace Sutton.
Saunders, Alfred Woods.
Somerton, William Knight.
Stewart, William Napier.
Thomas, William.
Wainwright, Percy.
Westerman, Thomas Kenworthy.
Wheeler, Alice Maud.
Young, William Frank.
FIRST EXAMINATION.
Certificates by approved examining bodies were received from
the under-mentioned in lieu of the Society’s examination : —
Baines, Louis Sydney, Sheffield.
Bembridge, Charles H., Alfreton.
Betten, Hugh, Brighton.
Church, Charles Edward, Andover.
Dalton, George Townsend, Northwich.
Davies, H. M., Llandrindod Wells.
Dowdy, Sidney Ernest, Kennington.
Gibson, Thomas, Brigg.
Griffin, Alfred Buckle, London.
Howorth, Christian W., Plumstead.
Thwaite, Ernest
Jones, John Lee, Ebbw Vale.
Lenfestey, L. d’Estreville, London.
Lund, Frederick Arthur, Rotherham.
Munro, Hugh Lennox, Brigg.
Nancarrow, Samuel, Falmouth.
Parkin, Ernest, Elsecar.
Powell, William Evans, Cardiff.
Quinton, Percy Julian, Stowmarket.
Seaborne, Lionel D., Wombwell.
Smith, Henry Llewellyn, Dorking,
ward, Liverpool.
48
PHARMACEUTICAL JOURNAL.
[Jan. 16, 1897
EXAMINATIONS IN EDINBURGH.
January, 1897.
MAJOR EXAMINATION.
One candidate was examined, but failed to pass.
MINOR EXAMINATION.
140
92
48
Candidates examined
,, failed
„ passed ..
Adan, James Watt.
Ball, Ernest Harry.
Broughton, Ernest.
Darley, Edward.
Faull, Arthur.
Ferguson, John Alexander.
Forrest, James Lindsay.
Furber, Robert Arthur.
Gardiner, William.
Gauldie, Norman Lewis.
Gow, Adam.
Graham, William.
Gray, Andrew.
Greig, John.
Haley, Benjamin Pawson.
Johnson, John William Baker.
Kennedy, Robert Ker.
Lamb, Thomas.
Linklater, Peter.
Logie, John Moffat.
McGregor, Duncan Anderson.
Mate, Max.
Miller, Arthur.
Milner, Jonah.
Ness, William Adams.
Nicol, Thomas.
Owen, Thomas Pritchard.
Pagan, Thomas.
Peebles, David.
Potts, Albert Edward.
Prescott, John.
Prophet, William Todd.
Ramsay, William Christopher.
Roberts, Rees.
Sheed, William.
Simpson, Gilbert.
Sinclair, James Pettigrew.
Smith, Foster.
Spence, Edward.
Spink, Richard.
Stringer, Horace.
Sturrock, James Nicolson Law.
Thomas, Penry Sidney.
Wilcockson, William.
Watts, Herbert.
Weir, Thomas.
Wharton, Anthony James.
Whitehead, William.
“FIRST” EXAMINATION QUESTIONS.
January 12, 1897.
LATIN.
Time, allowed — from 11 a.m. to 12.30 p.m.
I. For all Candidates. Translate into Latin : —
1. Augustus, the emp: ror of Rome, is dead.
2. Build the walls of our city.
8. Within three days we shall flee from Athens.
4. Having heard these things, he set out for home.
5. Will you not teach your daughters the art of singing ?
II. Translate into English either A (Caesar) or B (Virgil).
(Candidates must not attempt both authors. )
A. — Caesar.
1. Helvetii, ea spe dejecti, navibus junctis ratibusque compluribus factis, alii
vadis Rhodani, qua minima altitudo flumtnis erat, nonnunquam interdiu,
saepius noctu, si perrumpere possent, conati, operis munitions et militum con-
cursu et telis repulsi, hoc conatu destiterunt.
2. Turn demum Ariovistus partem suarum copiarum, quae castra minora
oppugnaret, mteit. Acriter utrimque, usque ad vesperum, pugnatum est. Solis
occasu suas copias Ariovistus, multis et illatis et acceptis vulneribus, in castra
reduxit. Quum ex captivis quaereret Caesar, quam ob rem Ariovistus proelio
non decertaret, hanc reperiebat causam : quod apud Gevmanos ea consuetudo
esset, ut matres familiae eorum sortibus et vaticinationibus declararent, utrum
proelium committi ex usu esset, nerne ; eas ita dicere : Non esse fas Germanos
superare, si ante novam lunam proelio contendissent.
Grammatical Questions.
(For those only who take C?esar.)
1. Decline, in the singular, ea ape ; and, in the plural, hoc conatu (Passage 1).
2. Give the principal parts of all the verbs in Passage 2.
3. Compare bonus, juvenis, malus, vetus ; and give the positive of summus,
imus, facillime.
4. Give, with examples, the chief uses of the dative in Latin.
B. — Virgil.
1. Aeneas scopulum interea conscendit, et omnem
Prospectum late pelago petit ; Anthea si quem
Jactatum vento videat, Phrygiasque biremes,
Aut Capyn, aut celsis in puppibus arma Caici.
Navem in oonspectu nullum ; tres litore cervos
Prospicit errantes ; hos tota armenta sequuntur
A tergo, etlongum per valles pascitur agmen.
2. Quinquaginta intus famulae, quibus ordlne longo
Cura penum struere, et flammis adolere Penates.
Centum aliae, totidemque pares aetate ministri,
Qui dapibus mensas onerant, et pocula ponunt.
Necnon et Tyrii per limina laeta frequentes
Convenere toris jussi discumbere pictis.
Mirantur dona Aeneae ; mirantur Iulum,
Flagrantesque Dei vultus, simulitaque verba,
Pallamque, et pictum croceo velamen acantho.
Praecipue lnfelix, pesti devota futurae,
Expleri mentem nequit, ardescitque tuendo
Phoenissa, et pariter puero donisque movetur.
Grammatical Questions
(For those only who take Virgil. )
1. Decline, in the singular, pelagus patens ; and, in tne plural, collis altior.
2. Give the principal parts of all the verbs in Passage 2.
8. Compare bonus, juvenis, malus, vetus ; and give the positive of summus, imus ,
facillime.
4. Give, with examples, the chief uses of the dative in Latin.
ARITHMETIC.
Time allowed — from 12.30 p.m. to 2 p. rn.
[The working of these questions, as well as the answers, must be written out
in full.]
1. Divide twenty-three millions four hundred and seventy-seven thousand
seven hundred and twenty-four by mdcclxxvii.
2. Find the value of 51 of — -i— of £44.
3J + 2J
8. Express as a vulgar fraction in its lowest terms : —
(1-205- -25) X (g-fj
1-4+3-375
4. Find the cost of painting the walls and ceiling of a room 16 ft. long, 15 ft.
wide, 13 ft. 4 in. high, at 2s. 3d. per sq. yd.
5. If 800 men could do a piece of work in 2 4 days, how many would be re¬
quired to do -3 of the same work in 12 days ?
6. If a dishonest tradesman uses a weight of 14-76 oz. for 1 lb. (avoirdupois),
and professes to sell his goods at the cost price, what does he gain per cent. ?
The following question must be attempted by every candidate : —
7. Write out the table used in the metric system for measuring the surface of
land. An estae measuring 1927 hectares is sold for 10100000 francs: find the
price per acre approximately in English money, taking a pound sterling as equal
to 25J francs.
ENGLISH.
Time allowed — from 3 p. rn. to 4.30 p.m.
1. Analyse
“ The stag at eve had drunk his fill,
Where danced the moon on Mcnan's rill.
And deep his midnight lair had made
In lone Glenartney’s hazel shade.”
2. Parse fully : —
“ And oft they thought him sinking,
But still again he rose.”
3. Point out the force of the following prefixes, and write words in illustra¬
tion : — ex, retro, anti, sym, arch.
4. In the following passage supply the necessary capital letters, and put in
the stops and inverted commas where necessary as i approached a pass in the
rocks four mounted men videttes I suppose suddenly dashed out from their
concealment and reined up their horses when close to mine who are you whither
going was quickly asked an Englishman travelling to beyrout was the reply
they held a moments counsel and then suffered me to pass
The following question must be attempted by every candidate
5. Write a short composition on one of the following subjects : —
(i.) Recent events in the Soudan.
(ii.) The influencj of air, soil, and water on hum: n health and longevity,
(iii.) Recent developments of Photography.
(iv.) “Industry is the secret of those grand results that fill the mind
with wonder.”
Jan. 16, 1897]
PHARMACEUTICAL JOURNAL.
49
LITER ARY_N0TES.
‘Science Progress’ for January is full of interesting matter,
and for the first time in the history of the paper, an article of
economic importance finds a place in its pages. In this article,
Mr. C. A. Barber takes an exceedingly pessimistic view of the
outlook for the sugar-producing British Colonies under existing
conditions, as it is asserted that unless Continental “ war bounties ”
cease, inevitable ruin stares those Colonies in the face. Professor
H. A. Miers shows how cholesteryl benzoate, azoxyphenol
and azoxyanisol are capable of forming what may be termed
“ liquid crystals,” self-contradictory though this term may
appear ; Professor J. Bretland Farmer treats of the cell
and some of its constituent structures; and Mr. John
Beddoe continues his consideration of that always interesting
topic — selection in man. Some results of experiments on the
larvae or plutei of sea-urchins are recorded by Mr. H. M. Vernon,
and appear likely to have an important bearing on the causes of
variation. Thus, he has established the fact that the ova of these
organisms are more sensitive to changes of environment, such as
temperature, at the time of impregnation than subsequently.
Other articles are on “ The Glossopteris Flora,” by Mr. A. C.
Seward; “Condensation and Critical Phenomena,” by Professor
J. P. Kuenen ; and “ The Origin of Lakes,” by Mr. J. E. Maw.
* The Climate of Bournemouth ’ is discussed by Dr. A.
Kinsey-Morgan (Wright and Co., Bristol, Is. net), in relation to
disease, especially phthisis. The subject is treated from the
point of view of climatic conditions, geological features, purity of
air, sanitary and meteorological conditions, morbific influences,
influence of the pines, etc. , and numerous cases of benefit accruing
from treatment in the Bournemouth district are recorded by the
author. The little book may therefore be consulted with
advantage by everyone in search of a suitable health resort.
‘ Successful Advertising ’ has reached its seventeenth edition,
and the authors — Messrs. Thomas Smith and J. H. Osborne —
naturally think their explanations of the secrets of success in this
direction are the correct ones. Be this as it may, those who con¬
template appealing to the public through the medium of advertising
pages can here find much food for thought. The problems dis¬
cussed include the preparation of successful advertisements, the
introduction of new articles, the free sample question, what can be
done with moderate capital, the tests of success, and other points
too numerous to mention but of primary importance to interested
parties. Moreover, the book includes the rates for advertising in
the leading London and provincial papers, in addition to lists of the
London, suburban and provincial daily, weekly, and monthly papers,
so that very good value is given for the price {2s. ) charged for the
book, which is published by the authors at 132, Fleet Street, E.C.
Die Umschau is the title of a new weekly scientific journal pub¬
lished by Messrs. Bechhold, of Frankfurt, It is intended to furnish
a popular summary of progress and research in all branches of
science, industry, literature, and art. The subjects dealt with
will be treated of in separate articles as occasion offers, or in annual
retrospects of particular departments. The services of a large
staff of distinguished authorities have been secured, and the list of
articles that will appear in the early numbers covers a very wide
range. The articles in the first number are on Volkerkunde, by
Dr. Max Buchner, of the Ethnographic Museum, at Munich ;
the Physics of Celestial Bodies, by Professor William
Huggins ; Music since the Death of Wagner, by Dr.
Hugo Riemann ; Criticism, by Leo Berg, of Berlin; the
Home of the Germans, by Dr. J. W. Brainier, of Greifswald ; A
Financial Review of the Year, by S. v. Halle ; besides some three
pages of short notes on various subjects. Articles are announced
upon old and new medicines by Dr. G. Arends, the editor of the
Pharmaceutisclie Zeitung ; on Chlorophyll by Dr. L. Marchlewski, of
Manchester ; Colour Photography, by Professor E. Valenta, of
Vienna ; the Utilisation of Molasses in Sugar Production by Dr. G.
Pulvermacher ; the Alchemists, by Professor F. Fittica, of Mar¬
burg. The price of the journal is 4 d. for a single number, and it
can be obtained through any of the foreign booksellers in London
for 2s. 6 d. per quarter, or by post for 3s. 6 d. a quarter.
‘ Our Weights and Measures,’ by Mr. H. J. Chaney, Super¬
intendent of the Standards Department, Board of Trade, is a
handsome volume (Eyre and Spottiswoode, London, 7s. 6 d.) con¬
taining much information on the subject of which it treats,
derived from authorised sources. It deals with the “ Imperial
System ” very fully from a historical point of view, but metric and
other standards are also described, as well as pharmaceutical
weights and measures, and measurements of various kinds. Fine
collotype illustrations, together with lithographs and woodcuts,
serve to render the work unusually attractive. Further reference
to its contents must be deferred for the present, but it may at
once be said that whilst the book should be very useful to
chemists and physicists, it must also prove of considerable interest
to antiquarians and scientific authorities.
The Calendar of the Pharmaceutical Society for 1897 is now
ready and contains the usual information respecting the Society,
but somewhat more condensed than usual. Thus, the Society is
now credited with no officials except the Secretary and Registrar,
or it would appear so from the fact that the familiar page headed
“Present Professors and Officers of the Society” is either missing
or so well hidden as to be difficult to detect. Doubtless the Secre¬
tary and Registrar is a host in himself, but persons buying the
Calendar naturally expect to find it useful for reference on all
points concerning the Society. Acts of Parliament, and extracts
from Acts, bearing on the trade of chemists and druggists, examin¬
ation and scholarships regulations, examination questions, excise
duties and regulations, naval hospital and poor law dispenserships,
and numerous other matters of the highest importance to everyone
connected with pharmacy are dealt with in this volume, which
may be obtained from the Secretary, 17, Bloomsbury Square,
W. C. , at the price of 2s. , or post free, 2s. 4Jd.
“Heavy Trial Balances Made Easy,’ by J. G. Craggs, F.C.A.,
(Scientific Press, Limited, 2s. 6 d.), is an exposition of a new
system for ensuring the agreement of trial balances, which is
described as being of the greatest value where accounts are very
heavy, and also where the operations of the business concerned do
not naturally fall into such sub-divisions as can readily be followed
by isolating the books of account to agree with them. The new
method is claimed to put checks upon fraud, carelessness
and indolence ; to lead to detection of culprits ; to convert
single into double entry ; and to be less expensive to
work than older plans adopted by accountants.
The Australasian Medical Directory and Hand-Book is
much more interesting than the usual run of such works, the
editor — Mr. Ludwig Bruck — having included a short account of
the climatic and sea-side health resorts in Australia, Tasmania,
and New Zealand. The book also serves as a general gazetteer of
nearly 1000 post towns in Australia, Tasmania, New Zealand, and
Fiji, as well as a local directory. The London publishers are
Messrs. Bailliere, Tindall and Cox, 20, King William Street,
Strand, W.C.
50
PHARMACEUTICAL JOURNAL.
[Jan 16, 1897.
THE STUDENTS’ PAGE.
NOTES ON THE FLOWERS OF JANUARY.
Ulex europceus. — The furze or gorse frequently produces flowers
from September to February, although March is the month in
which they are in perfection. The plant is an undershrub
(suffruticose), having a woody perennial stem, but rarely attains,
except in woods, a height exceeding 3 or 4 feet. The branchlets
are developed in the form of thorns, and the veins of the leaves as
spines. The small trifoliate leaves are, however, well represented
in seedling plants. Beneath each flower there is usually one
spine representing the central leaflet, the other two which represent
the lateral leaflets being developed as bracts beneath the flower.
The calyx is two-lipped with spreading hairs. The corolla is
papilionaceous, the two lateral petals (wings) being longer than
the lower one (keel) and being locked into it, so that when an
insect alights on the wings the stamens are forced out of the keel.
The fruit is a short pod, containing several seeds, which are
scattered to a distance, when mature, by the sudden twisting
backwards of the valves when the pod dehisces. The curious
arrangement of the spines, which are longer than the pods and
point downward, prevent the attacks of birds and mice until the
seeds are ripe. In the dwarf furze, Ulex nanus, which flowers in
summer, the wings are shorter than the keel, and the hairs on
the calyx are appressed.
Capsella bursa-pastoris. — The shepherd’s purse affords an excel¬
lent example of the great variability in the shape and development
of leaves, according to their environment. Hardly two specimens
are exactly alike in outline. They are normally more or less
pinnatifid, but are sometimes almost entire. The lower leaves
are usually depressed so as to form a stellate rosette on the ground.
The conditions of dryness or moisture and the character of the
soil as bearing upon the form of the leaves are worth observing.
The inflorescence is a raceme, i. e. , the flowers are stalked on a
central axis, the outer, which become the lowest, opening first.
It may be noted as characteristic of the Cruciferce that the
individual flowers have no bract beneath them, these occurring
only where the inflorescence branches, as it does in some
genera. The flowers, which are small and white, have four sepals,
four petals, and six stamens. Two of the latter are shorter than
the other four (tetradynamous), and have two green glands or
nectaries at the base. The fruit is compressed and short (silicula)
and triangular, with the apex of the triangle nearest the flower
stalk. The edges of the carpels are visible in the centre of the
fruit as a vertical line, and give rise in the interior of the fruit to
a membranous partition (replum) which separates the fruit
into two cells. The seeds are attached in two rows to the
edge of each of the carpels (i.e., the modified leaves of which
the fruit is formed). As the replum is narrower than the
broadest diameter of the fruit, the fruit belongs to the section of
the Cruciferce named Angustiseptce. In this section the central line
of union of the carpels is always easily seen. Sometimes the shep¬
herd’s purse may seem to be covered with whitish patches of a
fungus, Cystopxis candidus, by which, and by another, Peronospora
parasitica, various parts of the plant become remarkably hyper¬
trophied, the petals becoming six times their usual length and the
stamens eight in number, whilst the stems look as if they suffered
from elephantiasis.
Senecio vulgaris. — The common groundsel requires the use of a
lens to examine it properly. * The root is fibrous and the leaves are
pinnatifid and irregularly incise-serrate, without any leaf-stalk
(petiole) and clasping the stem at their base (amplexicaul). The
hairs on the leaves are beautifully moniliform ; they may be
found more abundantly on the pedicels beneath the flower-heads.
The flowers are arranged in narrow capitula, which have an
outer row of black-tipped bracts (phyllaries), and a single row of
similar but larger inner ones, which is characteristic of the genus.
The florets are all tubular, + and have no bractlets (pale;e) at their
base. The ovary is inferior, and is surmounted by a ring of un¬
branched hairs (pilose pappus) which represents the calyx. The
* For directions how to examine a plant see Ph. J. [3], xxv., p. 313,
or Holmes’ ‘ Botanical Note Book.’
f Occasionally a plant may be found with a single row of revolute,
ligulate florets, thus approaching 8, sylvaticus, in which revolute,
ligulate florets are always present. The latter, however, is a taller plant
with tougher stems and gland tipped hairs.
corolla is five-toothed, and the stigma is forked. The style at first
is shorter than the stamens, and the two lobes of the stigma are
pressed together, but as the style elongates the stigma pushes
the pollen before it through the tube formed by the united
anthers, so that as the sticky surface of the stigma is not ex-
osed until the pollen is pushed out, each individual floret cannot
e self-fertilised. The outer florets open first, so that each flower-
head (capitulum) has a centripetal inflorescence. The central
flower-head is, however, the first of the corymbose cyme to open,
so that the general inflorescence is centrifugal, thus affording an
instance of mixed inflorescence. The fruits are furnished with
hairs, which, when moistened, exude mucilage, and thus cause
them when blown about to adhere to the soil. *
Correction. — The interpolation of the word “less” in the sixth
line of the paragraph descriptive of the mistletoe fruit {ante, p. 30)
was an inexplicable compositor’s freak. If the word be deleted,
the sentence will then read correctly.
THE STUDY OF THE B.P.
The notes published under this heading will deal chiefly with
such points as are insufficiently dealt with in the elementary text¬
books to which apprentices or students usually have access. In
the case of any points which are not sufficiently clear being over¬
looked in this page, students are invited to communicate with
the Editor respecting their difficulties.
Acacice Gummi. — The iodine test is of course intended to detect
the adulteration of powdered gum with starch or flour. The
solution must be cooled before adding the iodine, because the blue
compound of iodine and starch is not formed in hot solutions.
Acetum. — The barium chloride test is intended to show the
absence of more than the quantity, 1 in 1000 (T per cent.) of
sulphuric acid which manufacturers are allowed to add to vinegar.
Note that the solution of chloride of barium must be the official
solution whose strength is defined in the appendix, p. 482.
Acidum Aceticum. — The zinc, hydrochloric acid, and lead acetate
test shows absence of sulphurous acid or sulphites. If such be
present the hydrogen evolved by the action of the zinc and acid
reduces the sulphurous acid to sulphuretted hydrogen —
H2S03 + 4H = H2S -I- 3H20.
The H2S then attacks the lead subacetate with formation of black
lead sulphide — 2H2S + Pb202C2Hs02 = 2PbS + H.,0 + 2HC2H302.
The same test is also given under acidum aceticum glaciale.
Hydrogen, owing to its affinity for oxygen, and especially in the
nascent condition, is an energetic reducing agent, and as such it is
employed in a large number of chemical reactions.
Acidum Benzoicum. — Benzoic acid can be prepared synthetically
in many ways, e.g., from hippuric acid and toluene. This syn¬
thetic acid is not official, and has not the agreeable odour possessed
by benzoic acid derived from benzoin, due to aromatic constituents
of the latter, which sublime with it.
Acidum Boricum. — This acid loses water when ignited, and leaves
a glassy residue of boric anhydride—
2H3B03 = B203 + 3H20.
Acid Carbolic. — The album] n test distinguishes it from creosote.
Compare also the ferric chloride test for the two substances.
Bromine water produces a precipitate of tri-brom-phenol by dis¬
placement of three hydrogen atoms by three atoms of bromine —
C6H6OH + 3Br2 = C6H2Br3OH + 3HBr.
Acidum Citricum. — The absence of precipitation when an excess
of the aqueous solution is added to a solution of potassium acetate
indicates absence of tartaric acid. If the latter be present, the
sparingly soluble potassium hydrogen tartrate (cream of tartar)
is precipitated. In this case a salt of potassium is used as a
reagent to detect tartaric acid, just as the latter may be used for
the detection of the former.
Acidum Gcdlicum. — Galls contain tannic acid. When the
powdered galls are boiled with diluted sulphuric acid the tannic
acid is hydrolysed — i.e., one molecule of water is taken up by one
molecule of tannic acid, and two molecules of gallic acid are
formed. The test with isinglass solution indicates absence of
tannic acid. The latter forms an insoluble compound with gelatin,
of which isinglass is chiefly composed.
* For further particulars see ‘A Year’s Botany’ (Rivingtons),
p. 220 to 223.
Jan. 16, 1897]
IrHARxMACEUTICAL JOURNAL.
51
Pharmaceutisal Journal
LONDON: SATURDAY, JANUARY 16, 1897.
THE COUNCIL MEETING.
The business last Wednesday was chiefly ordinary routine.
After the minutes of the previous meeting had been
•confirmed, and the President had drawn attention to
the fact that a distinguished Honorary Member of the Society
lias been raised to the Peerage, he proceeded to propose a
resolution in reference to the death of Mr. Schacht, and in
•doing so paid a graceful tribute to his memory. The motion
was seconded by the Treasurer acting as Vice-President,
supported by Messrs. Savory, Southall, Atkins, Bottle,
and Symes, before being passed by unanimous consent.
The additions to the Society were numerous, comprising
31 members, 63 associates, and 91 students. In reference
to the latter class, Mr. Bateson drew attention to the educa¬
tional work now in progress at Kendal as promising to afford
pharmaceutical apprentices and assistants a means of improv¬
ing their knowledge of science.
The report of the Finance Committee did not call for
snecial comment, except in connection with the Benevolent
Fund. In response to the recent appeal for contributions to
make up the deficiency in the amount available for payment
of the annuities now falling due, several sums have been
received from students, local secretaries, and the directors of
the Chemists’ Mineral Water Association.
On the recommendation of the Benevolent F und Committee
six grants, amounting in the aggregate to seventy-six pounds,
were ordered to be paid, and the Secretary announced the
•death of J. S. Jarvis, an annuitant since 1892. Mr. Atkins
mentioned the case of Robert Kirkby, an orphan child, for
whose election to the Wanstead Orphan Asylum he earnestly
solicited support. In connection with this appeal the Presi¬
dent expressed regret that in so many instances orphans in
this position are not eligible as recipients of the benefits of
the Society’s Orphan Fund. In answer to an inquiry by
Mr. Allen, the disqualification was explained as resulting
from the parents of the children requiring assistance not
having been Members or Associates of the Society, or sub¬
scribers to the Benevolent Fund.
ADVERTISING AND THE PRESS.
An important article in the current number of the
Nineteenth Century, written by Mr. H. J. Palmer, the editor
•of the Yorkshire Post, draws attention to the great develop¬
ment of advertising enterprise which has resulted from
recent improvements of the rotary printing press. He shows
that until within the last three years, the daily newspapers
of large circulation could not add to their size, and were
consequently unable to comply with the wishes of a daring
advertiser disposed to occupy an entire page. But when
improved presses were introduced capable of turning out ten
or twelve pages at double the speed — the old ones produced
eight pages — the newspaper proprietor has been able to give
both advertisers and readers an extra page or two. The
result has been that advertisers have taken advantage of the
opportunity and, though the increase in the size of a paper
sold for a penny has been costly, the extra expense has
been more than repaid by the largest advertising revenue
the British press has ever known.
So far all parties concerned have been benefited : the reader
has had nearly double his former quota of news ; the papers
have gained in revenue and advertisers have obtained the pro¬
minence to which they are entitled whenever they pay for it.
A certain control of the relation of advertisements to news
must necessarily be exercised in the interest of the reader, as he
will always remain the predominant partner. As an experienced
editor, Mr. Palmer acknowledges the importance of adver¬
tising and the obligation of the British Press to advertisers ;
he admits that it owes its prosperity chiefly to them. But
he also holds that as the most powerful engine at the disposal
of those who wish to bring their wares before the public, the
Press has had something valuable to sell in the ordinary way
of business exchange, and that the profit derived from ad¬
vertising does not in the least degree invalidate the main¬
tenance of a policy of independence and of incorruptible
fidelity to the public interests. But the point to which Mr.
Palmer’s article relates is that the advertiser is not always
content with the advantage he ■ has gained and is showing a
disposition to push it further, under the impression that a
newspaper is nothing more than an advertising machine. Not
content with his own recommendation of his wares, he is
beginning to hanker after a recommendation bearing the im-
primatur of the journal he is pleased to patronise — is some¬
times willing to pay for such masked advertisement — and pur¬
suing this line of enterprise by subtle methods he has already
achieved so distinct a measure of success that the time has
come for newspaper managers and the public to consider the
threatened breach in what should be an absolutely inviolable
principle.
This is the point to which Mr. Palmer’s article is directed,
and he represents the danger which threatens the Press as
bribery. He adds that though some papers would refuse to
insert advertisements set in news type and placed so as to be
indistinguishable from ordinary news and to be taken as em¬
bodying the veritable recommendation and opinion of the
editor of the journal in which the reader reposes his trust,
there are half a dozen who will accept the alluring proposals
of advertising agents for one that will refuse. As an
instance of this corroding innovation Mr. Palmer speaks of
journals — not corning within the pale of the highest class,
although rightly regarded as papers of reputation and enjoy¬
ing public confidence accordingly — where there are lauda¬
tory paragraphs in connection with company schemes com¬
mending them to investors. Such paragraphs, he says, are
supplied by an advertising agent, who either pays for them
or promises in return the preferential insertion of remunera¬
tive advertisements relating to the same or other companies.
The feeble attempts on the part of papers, so selling their
editorial influence, to qualify the effect are denounced as
shams, because the public knows nothing of their significance
and because the whole object of the advertiser is to deceive
the public into the belief that the editor is commending the
speculation to which reference is made.
Granting the reality of the practice here referred to, there
can be no question that it is not only immoral but certainly
suicidal to both advertisers and the proprietors of newspapers
who lend themselves to the system. The public will soon
learn to distrust alike the newspapers that sell their journal¬
istic virtue and the schemes that are puffed by them, so that
both parties to the deceit will sooner or later be placed in
the position of actors playing to an empty house.
52
PHARMACEUTICAL JOURNAL.
[Jan. 16, 1897
ANNOTATIONS.
Invisible Light— to use the somewhat contradictory term
employed to distinguish the phenomena associated with the parts
of the spectrum not visible to the unaided human eye— received
attention at the hands of Professor Silvanus Thompson, at the
Royal Institution, last week. The method of sifting out the short,
actinic waves from visible light was successfully demonstrated,
the normally invisible ultra-violet rays being rendered visible, as
well as reflected, refracted, and polarised, just like ordinary light.
Fluorescence and phosphorescence were beautifully illustrated,
and shown to be due to the ultra-violet rays, whilst the power of
the rays to dis-electrify electrified bodies and to act upon a photo¬
graphic plate were clearly manifested. Colour-photography
naturally came in for a large share of attention, fine specimens of
Lippmann’s and Ives’s work being exhibited on the screen.
The Infka-Red Part of the spectrum was next treated, the
longer calorific waves being in turn sifted out from visible light
and shown to be cut off by transparent glass but transmitted by
opaque ebonite. The radiometer, thermopile, and bolometer were
put in action, the heat-indicating power of paints prepared from
mercuro-mercuric iodide (?) and the double iodide of mercury and
copper was demonstrated, and the infra-red rays were also reflected,
refracted and polarised, thus fulfilling the conditions required of
rays classed as light waves. Still more interesting was the
demonstration of the gigantic waves discovered by Hertz,
which fulfilled all the required conditions and helped to complete
the inference that all light waves, whether visible or invisible, are
really electric waves of different sizes. But more information
concerning these giant waves will be forthcoming at Professor
Bose’s lecture on Friday, January 29.
Rontgen Light — the only known kind that as yet refuses to be
reflected, refracted, and polarised, as all well-conducted light
ought to do, but prefers for the present to masquerade as an
exception to the general rule — occupied the whole of the concluding
lecture, which was all too brief even though it greatly exceeded
the time limits nominally set. The effects following the exhaustion
of tubes through which electric discharges were passed naturally led
to a fine exhibition of Geissler-tube phenomena. *Jhe mercurial pump
was then shown and described and set to work, the Crookes’ tube
phenomena were shown, and the properties of kathode light
demonstrated. Crookes’ shadows were shown, the greenish-yellow
light in the tube was deflected by a magnet, and its luminescent
and mechanical effects were illustrated. Reference to the libera¬
tion of these kathode rays from their transparent prison house by
Lenard, who found that they pass readily through a plate of alu¬
minium inserted in the tube as a window, was followed by a
concise summarised account of Rontgen’s discovery of the
mysterious dark rays, which as yet can only be rendered visible by
the interposition of luminescent bodies, and are apparently
capable of penetrating most substances that we have been in the
habit of regarding as opaque. Some rays of a different nature
seem to be associated with these so-called X rays, and Professor
Thompson finds that they are capable of deflection by a magnet.
But no more is known concerning them at present.
“ The Light that Never was on Sea or Land,” until Crookes
invented his famous tube, was unfortunately introduced to the
audience by Professor Thompson with an unworthy gibe directed at
■“photographic papers and other papers conducted by unscientific
(sic ) persons.” Ignoring his own previous lapses in the matter of
chemical details and his somewhat painfully insufficient acquaint¬
ance with the photographic processes he referred to, the lecturer
complained that Rontgen’s discovery had been claimed as a photo¬
graphic one. But the photographic effects of the X rays were the-
first to be announced to the world, and those effects were as novel
as the discovery of the existence of the X rays themselves.
There was therefore a real photographic discovery no less than
an optical or electrical one. But this lapse may be forgiven a
lecturer whose only object for the time being was to instruct
and amuse juveniles — the average age of those “juveniles’*
by the way, being about thirty years — for he imparted a very
living interest to his subject, and communicated the little there is
to relate about the Rontgen rays as simply as a scientific tale can-
well be told. Sir George Stokes’ theory of the nature of the rays—
that they consist of waves of exceedingly short vibration, of only a
single ripple each as it were — was quoted approvingly, and this in¬
teresting series of lectures on electrical waves, for this is what
they were in reality, was concluded by the statement that the-
universe is full of different sorts of vibrations, of which we have
not the remotest knowledge or slightest suspicion. “As years go by,
however, and one apparently useless observation leads another man
to make an observation to some purpose, so science will creep
from point to point, and the cloud of ignorance will be rolled back
farther and farther, giving light where we now have but darkness.’*
The Royal Institution lecture season begins in earnest on
Tuesday next, January 19, when Professor Augustus D. Waller,
M.D., F.R.S., Fullerian Professor of Physiology, will deliver the
first of a course of twelve lectures on “Animal Electricity.” On
Thursday, January 21, Professor Henry A. Miers, F.R.S., will
begin a course of three lectures on “Some Secrets of Crystals”?
and on Saturday, January 23, Mr. Carl Armbruster will deliver the
first of three lectures on “Neglected Italian and French Com¬
posers.” The Friday evening meetings of the members will
commence on January 22, when Professor Dewar will deliver a
lecture on “ Properties of Liquid Oxygen.” Professor J. C. Bose,
Professor of Presidency College, Calcutta, will deliver his discourse-
on “The Polarisation of the Electric Ray” on Friday evening,
January 29, and not on February 5 as previously announced. The
discourse on the latter date will be delivered by the Bishop of
London, who will take as his subject “The Picturesque in
History.” Several intellectual treats are therefore in store.
The Lavender Industry has been the subject of the latest-
“ decline-of-British-industry ” scare, the following paragraph
having gone the round of the London dailies : —
Owing to a series of bad seasons, but principally to the large quantity of
foreign essential oils imported lately, the lavender industry of Hitehin is
threatened with extinction. Hitehin and Mitcham have for years divided
honours in producing England's supply of lavender water, the surroundings and
sub-soil of chalk being peculiarly favourable to the plant’s growth. The principal
growers at Hitehin are Quaker gentlemen. The acreage under cultivation, a
large grower assured a correspondent, is rapidly declining, and the plant bids-
fair to go out of cultivation altogether.
As might be expected, this scare had as little justification as in
most other cases, for Messrs. W. Ransom and Sons state that it is-
totally incorrect to say that the lavender industry at Hitehin is-
threatened with extinction owing to a series of bad seasons
and the importation of foreign essential oils. The acreage under
cultivation by the principal growers in Hitehin is not de¬
creasing, and the product of last season’s distillation was larger
than for several years previously. The severe winter of 1894-95
certainly destroyed a large portion of the plants, but the stock
Jan. 16, 1897]
PHARMACEUTICAL JOURNAL.
53
was replenished by cuttings taken from those that survived. The
importation of foreign oils, it is pointed out, cannot extinguish the
demand for the English product, which is entirely different from,
and vastly superior in aroma to, any oil distilled elsewhere, and the
fact is emphasised that there is no prospect of the extinction of
the industry, either at Hitchin or in the Mitcham district. Messrs.
Ransom’s statements are confirmed by Messrs. Perks and
Llewellyn, of Hitchin (see p. 59), who say that far from enter¬
taining pessimistic views regarding the cultivation of lavender,
they contemplate putting a much larger acreage under cultivation.
That English Lavender Oil is of superior quality to oil
obtained from lavender grown out of England is a fact so
well established that the sensational paragraphs published may
have caused a thrill of regret that in future there will be no more
“sweet lavender,” but only the less fragrant exotic product.
In addition, however, to learning from authentic sources that
there is not the least foundation for the alarming statements
that have been made as to the extinction of lavender cultivation
in this country, and that those who prefer the superior lavender
water, made with English oil, have no reason to fear that the
supply will cease, we are informed by the principal growers of
lavender that the oil distilled last year was of exceptionally fine
quality, besides having been produced in larger quantity than for
several years past. Moreover there is no evidence of diminution
in the demand for the home product, although it may have been
for a time partially supplanted by foreign oil at the time when the
price of English oil was at a very high figure in consequence of
apprehended scarcity, and in cases where cheapness was con¬
sidered more than quality.
The Society or Public Analysts held its annual dinner at the
Criterion Restaurant, London, on Wednesday last, Dr. Bernard
Dyer, the newly-elected president, occupying the chair. The
growing importance of this Society as a public body may be esti¬
mated from the large number of distinguished guests who attended,
including many leading scientists. Mr. Walter Hills, President of
the Pharmaceutical Society, was amongst those present, a happy
augury, it may be hoped, of the maintenance of friendly
relations between pharmacists and analysts. Amendment of the
Sale of F ood and Drugs Act naturally formed the chief topic in
the speeches delivered, and Mr. Hudson Kearley, M.P., who
responded for “The Houses of Parliament,” expressed the hope
that there may shortly be a statement that the Government
intends to introduce an amending Bill at the earliest opportunity.
Analysts’ Differences. — Comparing the decisions given in
some cases of prosecution under the Food and Drugs Act with the
evidence produced on both sides, the necessity of more efficient
means of estimating the value of such evidence is too frequently
apparent. This is especially the case when there is such a conflict
of evidence that a magistrate considers he has to believe one or
other of the witnesses. That was the position taken by the
Linlithgow Sheriff in regard to two public analysts who gave
directly opposite evidence concerning a sample of reputed butter,
one declaring that it was genuine, while the other stated that it
contained 76 per cent, of fat not derived from butter. A decision
based upon the Sheriff’s belief of one witness rather than the
other is in such a case eminently unsatisfactory, and apart from
its prejudicial reflection upon the discredited analyst, there cannot
be on such a basis any certainty that the decision is just to
the person prosecuted. The testimony of both analysts was
probably honest, and the discrepancy between them merely a
result of erroneous inference on one side or the other. In fairness
to them as well as to all concerned, the settlement of such a case
demands something more than mere belief, and it could only be
arrived at by reference to an authority technically competent to
appraise the data on which conflicting evidence was given. For
want of provision for such reference, offenders against the Food
and Drugs Act may escape, or unmerited hardship may be inflicted.
Analytical Differences in regard to the detection of such a
poison as arsenic have recently occurred in connection with
arsenical soap, and a somewhat dangerous application has been
made of the maxim de minimis non curat lex, as it has been con¬
tended that when soap contains only one hundredth part of a grain
of arsenic to the pound, arsenic is not present. If the question
at issue had been one as to purity, there is reason for thinking
that such an argument would be inadmissible, but in a prosecution
that is to be supported only by the entire absence of an ingredient
stated to be present, there would seem to be still less reason for
disregarding, even an infinitesimal proportion of it. Moreover, if the
above-mentioned legal principle be once admitted in reference to
poisons there is no telling what mischief may be done, or where
the line is to be drawn between poison and the opposite. A corre¬
spondence now going on in the Lancet serves to show that on this
point there may be very wide and perplexing differences of opinion.
Arsenical Soap continues to provoke magisterial decisions that
differ in variety, but on the whole there is a pretty general agree¬
ment that it must be regarded as a drug, and inability of public
analysts to detect the presence of arsenic in samples bought by
inspectors under the Sale of Food and Drugs Act is promptly
followed by the imposition of fines. Considering that arsenic i3
undoubtedly present in most cases and can be detected by resort¬
ing to suitable methods, it seems odd that innocent tradesmen
should have to pay for the tune piped by inefficient analysts.
But so the matter stands, and is likely to remain until some one
plucks up sufficient courage to risk money on an appeal. Accord¬
ing to the Wimbledon Post, a local case is to be carried further, which
was dismissed recently — on the ground that if the soap, however
named, contained no arsenic, as asserted by the prosecution, it
could not be a drug — and it is stated that the appeal will probably
be heard some time in March. This is good news, and for the sake
of retailers it is to be hoped it is true.
The Results of the Qualifying Examination deteriorate as
steadily as those of the “ Major,” but the proportion of failures
has attained a much higher point in the former case. It was noted
last week that the percentage of rejections at the “Major” has
risen from 49 66, in 1894, to 57 14 during the present month, but
the Minor examination results for the past three years have shown
the following percentages of rejections : — 1894, 62'83 ; 1895, 65 72 ;
1896, 65 ’28 ; and the lists published this week show that the per¬
centage has attained the very high figure of 67 ‘26, the proportions
at Edinburgh and London being virtually identical. Contrast this
figure with the results of the latest examination in Berlin, when
only four candidates failed out of twenty-four, and the effect pro¬
duced is not one of unmixed cheerfulness.
The Chemists’ Thirty-first Annual Ball will be held at the
Portman Rooms, Baker Street, W., on Wednesday next, January
20, and persons desirous of acting as stewards or requiring
tickets should communicate at once with the Honorary Secretary,
Mr. John C. Umney, 48 and 50, Southwark Street, S.E. Remit¬
tances must accompany all applications for tickets (lady’s, 12*. 6d. ;
gentleman’s, 17s. 6 d.). These include refreshments, supper, and
wine. Mr. Dan Godfrey’s Quadrille Band, conducted by Mr. Dan
Godfrey, will be in attendance, and dancing commence at 9 p.m.
54 PHARMACEUTICAL JOURNAL. [Jan. 16, 1897
The Students’ Page has been received with greater enthusiasm
than any single new feature ever introduced into the Journal
before, both old and young readers having communicated favour¬
able comments, not only from themselves but also from their
neighbours and friends. This is decidedly encouraging and,
coupled with the fact that the material for such a page is practi¬
cally exhaustless, tends to encourage the hope that this new
graft on an old growth may flourish exceedingly for many long
years to come. But students must bear in mind that the matter
rests in great measure with themselves. If they require aid and
seek it we are always glad to assist them, but everyone gets tired
in time of thrusting food into unwilling mouths. On the other
hand, if they apply in crowds each one must be content to await
his turn. But a little more enthusiasm like that manifested in
letters published last week and this is always useful, and we
especially commend the practical appreciation indicated in the
case of our Irish correspondent whose letter appears on page 60.
Ireland has certainly scored over Great Britain for once, in
matters pharmaceutical.
The Huxley Memorial Fund now amounts to £2900, and
further additions to the Fund are expected. Various local
institutions and scientific societies have subscribed handsomely,
Bristol, Leeds, Leicester, Adelaide, Sydney, New Zealand and
Calcutta having been conspicuous in this respect, whilst British
Guiana, Cairo, the East Indies, and Mauritius have also contributed,
in addition to the United States, France, Germany, Austria
Hungary, Holland, Belgium, Switzerland, Scandinavia, Italy,
Portugal, Russia, Servia, Mexico, Peru, Arabia, and Japan. This
world-wide support, as the Daily News fitly terms it, is well
merited, as Huxley’s labours in the cause of science fully justify
the hope that a form of memorial may be secured in which persons
of all nationalities shall participate, in addition to the statue and
medal already decided upon. The full-sized model for the statue
on which Mr. Onslow Ford, R.A., is engaged is said to be nearly
completed. The marble statue itself will be placed in the Central
Hall of the British Museum of Natural Science, South Kensington,
near the statue of Darwin. The design for the Royal College of
Science Medal has been prepared by Mr. L. Bowcher, and the dies
are now being executed. Those who have not yet contributed to
the Fund may be glad to be reminded that donations can be sent
to Messrs. Robarts, Lubbock and Co., 15, Lombard Street, E.C.
A Wave-Motor is the latest outcome of the inventor’s ingenuity,
according to the Daily Mail. This new economiser of the world’s
energy is described as consisting of a cylindrical tube that pro¬
trudes a few feet above the water-level and is fixed to a submerged
plane, together with a cylindrical buoy surrounding the tube, which
floats on the waves and has a pump barrel attached to it below.
Oscillation of the buoy up and down the tube is the source of
power, for the whole apparatus resembles a reversed engine
cylinder, and the barrel with the attached buoy is guided by the
fixed piston-rod or tube in its movement. The inventor, Mr. B.
Morley Fletcher, C.E., of Westminster, is said to have tried the
apparatus in the Thames and in the sea, but public demonstrations
are promised for the present year. The main value of the motor
is stated to consist in the fact that it provides a point of resistance
which is fixed in relation to the vertical motion of the waves, but
varies with the level of the water in which the machine floats and
its horizontal movement. The Morley -Fletcher motor will certainly
have a great future before it, if it realises the expectations this
announcement raises.
THE WORhD Op PHARMACY.
- - — ♦ -
BUSINESS MEETINGS.
Pharmaceutical Chemists’ and Apothecaries’ Assist¬
ants’ Association of Ireland, Friday, January 8. — Mr. W. J.
Hardy, Vice-President, in the chair. — A debate on the question
Is the Preliminary Examination of the Pharmaceutical
Society (Ireland) a Sufficient Test of Preliminary
Education ?
was opened by Mr. Harris, who said the preliminary examination
might be regarded as the starting point of the chemist’s profes¬
sional career, and was necessary as a means of securing a certain
standard of education in all comers. In his opinion the present,
test for the entrance to pharmacy was sufficiently searching. —
Mr. Alister said that now the cry of higher education was
everywhere being raised the necessity for a more searching pre¬
liminary examination for pharmacists became apparent. The-
preliminary examination was either not sufficiently searching,
or those who got through must have set themselves to unlearn
what they had already learned. Pharmacists should not forget
that a good educatiori was the foundation of a boy’s future
successful career. Unhappily, however, it seemed as if the wheels
of pharmaceutical education were at a standstill, and that things in
this direction instead of getting better were going from bad to
worse. — Several others having spoken, the Chairman, in putting the
question, said that ten years ago the Pharmaceutical Society’s
examinations were of a much lower standard than at present, but
the Society was advancing with rapid strides. It would be fatal
to pharmacy if all its followers were highly educated (sic), astheeffect
would be that the pharmacist would be too big a man to go behind
the counter. The meeting then divided, and the Chairman
declared amid applause that the negative side of the question was
carried by a majority of five votes.
Liverpool Chemists’ Association, Thursday, January 7. —
Mr. A. C. Abraham, President, in the chair. — Mr. Glyn-Jones.
attended to explain the programme of the
Proprietary Articles Trade Association.
At the outset Mr. Jones ran over the various objections made by
members of the trade to the P.A.T.A. These were shortly that
the business in proprietary articles was an excrescence upon
pharmacy pure and simple, and could very well be allowed to drift
away from it to the benefit of pharmacy generally, and that, con¬
sequently, to support the P.A.T.A. would be practically deferring
this much to be desired consummation. Secondly, men had an
objection to being tied down in their methods of conducting busi¬
ness, and wished for a free hand in their trading. To the first
objection he would say that, unfortunately, the houses in which
this ideal pharmacy was or could be practised were very few and
far between, and he would refer objectors on this score to the
article which recently appeared in the Pharmaceutical Journal on
“ The ‘ Pharmaceutical Journal’ and Changed Ideals,” from which
they would gather that pharmacy pure and simple could scarcely
be said to exist. If those who were in the enviable position of
having purely dispensing businesses could see no advantage to be
got out of the P.A.T.A. they might at least join it so as to assist
their less fortunate brethren, who undoubtedly formed the large
majority of the trade. The second objection was met by the
assurance that membership of the P.A.T.A. did not bind chemists
down to any particular price or profit, it simply defined the minimum
price at which proprietors were willing to see their goods sold. A
very lucid and satisfactory resume, of the work already done by the
Association, and its future programme was then laid before the
meeting by Mr. Glyn-Jones, who said that what they would do in
the future naturally depended on the manner in which they were
supported by chemists, and to enable them to appeal to the pro¬
prietary medicine makers effectually it would be absolutely
necessary to show a larger proportion of the trade members
of their Association than at present, for out of some 8000
chemists in business only about 1700 had as yet joined.
The hardest argument against the Association was the holding back
of the very men it was intended to benefit. It was an undoubted
fact that proprietors generally could quite see the benefit to be
derived by them from chemists stocking their goods, and were
JAN. 16, 1897]
PHARMACEUTICAL JOURNAL.
55
beginning to perceive the truth and force of the statement that it
is Better to sell a gross of an article divided among a dozen or more
chemists scattered over a large area of country, than to sell it to
one man or stores, where it is used as a bait for a time to draw
other custom and then dropped. Therest of Mr. Jones’ speech covered
the same ground as other speeches that have been reported in the
Pharmaceutical Journal of late. — After some remarks by the
President, who said Mr. Jones had put the whole affair before the
meeting in a very satisfactory manner, Dr. Symes proceeded to
point out that nothing could be done except by judicious
combinations as far as cutting was concerned, and he moved —
"That this meeting of the chemists of Liverpool and the district expresses
its hearty approval of the aims and objects of the P.A.T.A., and would
urge upon all proprietors the advisability of joining it.”
Mr. J. Smith seconded the motion, which was also supported by
Mr. T. S. W okes and others. The resolution was then put to the
meeting, which was a large and representative one numbering
close upon eighty, and passed unanimously. Upon the pro¬
posal of Mr. J. Smith, the Liverpool Chemists’ Association
undertook to look after the interests of the P.A.T.A. so far as en¬
rolling members was concerned, and many were forthwith entered
on the roll. It was intimated that Messrs. J. Thompson, the well-
known Liverpool wholesale house, had joined the P.A.T.A. A
letter was read from Messrs. Evans, Sons and Co. , saying that the
matter was one in the hands of the retailers entirely, and there¬
fore they preferred to leave it to them to decide as to whether they
would join the P.A.T.A or not.
Liverpool Pharmaceutical Students’ Society, Thurs¬
day, January 7. — Mr. Peirson, Vice-President, in the chair. — Mr.
J ohn Turcan described a
“Tour in North Wales”
with the aid of lantern illustrations, most of which had been made
from photographic views taken by the lecturer and others by the
President, Mr. John Jones, and the Treasurer, Mr. R. H. Mitchell.
These views were of a high order, and embraced scenes in Liver¬
pool— the excursion very appropriately being supposed to start from
the University College, of which some fine illustrations were
thrown on the screen — the Landing Stage, Chester, and then down
through the Vale of Clwyd, Llangollen, Bettwys-y-Coed, and the
ascent of Snowdon.
Glasgow and West of Scotland Pharmaceutical
Association, Thursday, January 7. — Mr. W. L. Currie, Presi¬
dent, in the chair. — The Hon. Secretary, Mr. J. Russell Anderson,
said that he had received a communication from Mr. Wokes,
Secretary of the Federation of Local Pharmaceutical Associations,
stating that it had been thought advisable by the Executive to
ascertain the opinions of the members of the affiliated associations
regarding the objects of the P.A.T.A., and enclosing a circular on
the subject. The circular contained nothing but what they were
all familiar with, and as they had had these matters under dis¬
cussion he wrote to Mr. Wokes intimating their decision. Perhaps
it would be well for him (the Secretary), on account of insinuations
which had been thrown out in regard to this matter, and bearing
on their own Association particularly, to say what was the actual
state of matters. He got a note from Mr. Glyn-Jones, asking him
to call a meeting of the Association, about the same date as
one in Edinburgh. That note was laid before the Council of the
Association, who decided to leave the P.A.T.A. to call its own
meeting. He wrote Mr. Jones to that effect, and when a meeting was
held in Edinburgh, he came to Glasgow to make inquiries. Mr.
Jones called on Mr. Currie, and at his request the matter was
again laid before a meeting of the Council, which adhered to its
former decision. He intimated that to Mr. Jones officially, and
also sent a private note, indicating what were the reasons of the
members of Council for not agreeing to call the meeting —
namely, that they should do nothing which would make
them appear as identifying themselves with the P.A.T.A. At the
same time he told Mr. Jones that he would be very pleased to let
him have the use of the lists of names and addresses in his pos¬
session, if they would be of any service to him. He had received
no acknowledgment of that letter which he wrote during the recess.
At the first meeting of this session Mr. Moir gave notice of
motion. It had been suggested that they should have had a
representative of the P.A.T.A. present, but that would have
been ridiculous, seeing that the motion arose from one of
their own members, and was discussed by their own members
— Mr. Currie said he was very much surprised at the action
which was likely to result from their last meeting. He had been
informed that the P.A.T.A. intended to hold a meeting in Glasgow
the following week, but, so far as he knew, no member of that
Association had received notice of it. He thought it rather un¬
fortunate that the P.A.T.A. should have adopted this mode of
procedure. — The Secretary stated that the number of members
on the roll at present was 185, which, he believed, was the largest
membership of any local association in Great Britain. — Mr. James
Robb then read a paper on “Botany as a Recreation,” for which he
was awarded a hearty vote of thanks.
Exeter Association of Chemists and Druggists, Satur¬
day, January 9. — Alderman H. Gadd, J.P. , President, in the
chair. — The Chairman said he thought it would be wise if fresh
officers were elected year by year, because members would thus be
induced to take greater interest in the Association. He therefore
proposed that Mr. J. H. Lake be elected President for the ensuing
year. — Mr. E. Lemmon seconded the resolution, which was carried
unanimously, and Mr. Lake, in acknowledging the compliment,
testified to the able services rendered by Mr. Gadd as President,
and said that, as his successor, he should be very pleased to do his
best to further the interests of the Association. — Mr. F. P. Rowsell
moved that Mr. H. Gadd be elected Vice-President for the ensuing
year, this being seconded by Mr. J. H. Lake, and carried unani¬
mously, Mr. Gadd returning thanks. — On the motion of Mr. Lemmon,
seconded by Mr. Bartlett (Heavitree), Mr. Rowsell was re-elected
Honorary Secretary for the ensuing year, and thanked for his
past services. Mr. Rowsell presented a statement of accounts,
which was passed, and the following were elected as the Com¬
mittee for the ensuing year : — Messrs. Stone, Reid, Bartlett,
Lemmon, H. W. Gadd, and Milton. The meeting next proceeded
to consider the advisability of holding a supper. — The Chairman
said it was proposed to hold a supper with the object of getting
the chemists of the district together, and to advocate the advantages
of the pharmaceutical classes which had recently been started at the
Technical College at the Museum. They had a laboratory second
almost to none, teachers most efficient, and classes for every branch
of pharmaceutical science, and it was hoped to send young men
from the College to London to pass their examination. He was
pleased to say that nearly all the chemists of the city had promised
to attend the supper, and it was proposed to invite chemists from
towns in the district. — Mr. J. H. Lake thought that if they held
a supper it would be an opportunity for the re-union of the chemists
of Exeterand the neighbourhood, and would be in many respectsmost
desirable. He therefore proposed that a supper be held on Friday the
29th instant. — Mr. Lemmon seconded the resolution, which was
unanimously agreed to. A small sub-committee was appointed
to make the necessary arrangements, and it was proposed to invite
the Mayor and Sheriff to attend. — Mr. Lake proposed that the best
thanks of the meeting be given to Mr. Gadd for the services he
had rendered in the past as President, and also for his generosity
in supplying specimens for the materia medica cabinet which was
recently placed in the Technical College. The resolution was
carried by acclamation, and Mr. Gadd having returned thanks,
the meeting terminated.
Pharmaceutical Society of Ireland. — Preliminary Exami¬
nation .-—The following have passed : J. Sullivan, J. O’Donoghue,
A. N. Rogers, P. J. Fleming (F. M‘Caughey and J. Marks equal),
T. Lynch (J. W. Fenton and P. F. Smith equal), J. H. Corken,
D. Chambers, C. B. Johnston, J. Guinan, C. E. Warner, E. E.
Wolfe. Thirteen candidates were rejected.
Midland Pharmaceutical Association, Tuesday, January
12. — Mr. R. Darton Gibbs, President, in the chair. — Mr. J. F.
Liverseege read a paper dealing with the report of the Select Com¬
mittee of the House of Commons on —
Food Products.
Referring to the parts of the report of the Select Committee re¬
lating to drugs, Mr. Liverseege said he thought the report con¬
tained much information which should interest the trade. Speak¬
ing of the proposed Court of References, he said the statement
that public analysts desired it for the purpose of their professional
standing was without foundation. They desired to know what to
call adulterated and what to call genuine. One thing
in connection with the recommendation puzzled him, for
56
PHARMACEUTICAL JOURNAL.
’[Jan. 16. 1897
in no way was that court spoken of with regard to drugs. It
was spoken of with regard to food, but not drugs. On the whole,
however, he felt that in some directions the alterations suggested
by the Committee would be valuable, but in other directions con¬
siderable modifications would be required to make the altera¬
tions acceptable to the trade and the Society of Public Analysts.
— The Chairman said that the proposal by the Society of Public
Analysts to step outside their ordinary duties to offer the world a cer¬
tain amount of protection was a matter that was open to considerable
criticism. He thought itwas an unfortunate thing that an Act of Par¬
liament intended for the protection of the public against adultera¬
tion should have mixed up two matters of so dissimilar a character as
food and drugs. No one could object to the proposed Court of Re¬
ference, if it was properly and fairly constituted. — Mr. J. Poole
said that he would like to see retailers represented on the Court of
Reference. — Mr. Jarvis said that many chemists bought drugs
believing they were pure, and by not testing them fell into error.
He thought before a prosecution followed the visit of the inspector
the seller should be warned that a certain article was not in accord¬
ance with the analyst’s standard, and that would enable him to
avoid a repetition of the offence. — Mr. J. Barclay thought
at least half of the difficulties which arose between public
analysts and traders were due to ignorance 'on the part of
public analysts of the pharmacist’s business. The analyst might
have a good knowledge of chemistry, but he was in many cases
entirely ignorant of pharmacy. — Mr. F. H. Alcock, Mr. Spilsbury,
Mr. Poole, and other members also took part in the discussion.
Midland Pharmaceutical Association (Trade Com¬
mittee), Friday, January 8. — It was resolved that in the matter
of the Bradford Chemists’ Association and the Charles A. Yogeler
Co. it was to be regretted that the company, whilst writing in the
following terms —
“ We consider ourselves in a measure in the hands of the majority of dealers in
proprietary medicines, and it is our intention and desire to study the
interest of the majority,”
did not see that this interest is best studied by fixing a living
profit on the firm’s goods. It was also regretted that the company
should have issued a circular at Bradford so inimical to the
interests of the majority of chemists, and agreed that unless some
more favourable move were made, it might be necessary for the
Committee to suggest to the members of the Association the
advisability of discontinuing to stock the company’s articles.
SOCIAL MEETINGS-
Plymouth, Devonport, Stonehouse and District
Chemists’ Association, Friday, January 8. — The annual
pharmacy ball was held at the Town Hall, Stonehouse, and proved
a brilliant success, over two hundred spending a most enjoyable
evening. Brock’s noted band was in attendance, and the catering
was satisfactorily carried out by Messrs. Matthews and Co.
Amongst those who accepted invitations were the Mayor of Devon -
Sort, Chairman Stonehouse District Council, C. Harrison, Esq.,
I.P., H. E. Kearley, Esq., M.P., and E. J. C. Morton, Esq.,
M.P. The following committee arranged the same : — Messrs.
G. Breeze, J.P., J. Harvey Bailey, H. C. Cantle, James Cocks,
G. H. W. Green, J. R. Johnson, C. T. Park, J. H. B. Swainson.
J. D. Turney, W. H. Woods, and F. Maitland, Hon. Sec., the
latter deserving the greatest credit for the success of the evening
by his energetic enthusiasm.
Brighton Junior Association of Pharmacy, Wednesday,
January 6.— Mr. T. Little in the chair. — This meeting was of a
“musical and social” character, and a large number attended.
A capital programme was well rendered, and the evening proved
a most enjoyable one. Votes of thanks to the chairman and
artistes concluded the proceedings.
Turpentine for Burns. — In the New York Medical Record
Maclnnes states that oil of turpentine applied to a burn of the
first, second or third degree will at once relieve the pain, and
promote rapid healing. A thin layer of absorbent cotton is placed
over the burn, and this is saturated with the turpentine, what is lost
by evaporation being replaced. Where large blisters are formed
these are opened on the second or third day. The turpentine
should be kept off the healthy skin if possible, as sometimes it
gives rise to pain. — B. M. J. Epit ., 2/96/56.
LEGAL INTELLIGENCE.
The Vegetable Ointment Case.
In the Court of Session, on January 6, the judges of the Second
Division gave judgment in the reclaiming note by the com-
plainers in the action by William Mathieson, Elsbank, Inverleith
Place, Edinburgh, Alexander Porteous, leather merchant, Rose
Street, Edinburgh, and other members of the Porteous Vegetable
Ointment Company against Archibald Porteous, carrying on
business at 33, Ann Street, Glasgow. The complainers sought te
have the respondent interdicted from manufacturing or selling
any ointment as Porteous Vegetable Ointment, or using that
designation on labels or invoices. Alexander Porteous, who sold
the recipe of the ointment to the Company for £1000, held that
when he acquired the goodwill of his father’s business of leather
merchant the recipe for the ointment was included in it, and that
he had been the only one who had manufactured it. The re¬
spondent, who is a brother of Alexander Porteous, averred that
the recipe belonged to no particular member of the family, and
that the ointment had been manufactured by several of them. In
the Outer House Lord Kincairney refused interdict, but held that
the respondent had no right to represent himself as the sole maker.
On this occasion their Lordships adhered to the Lord Ordinary’s
decision.
The Lord Justice Clerk said the proof in the case satisfied him
that whatever was the origin of this ointment, the name of
Porteous Vegetable Ointment had come down from an early period
through certain members of the family of Porteous, and he was
satisfied that there had never been any exclusive right on the part
of any individual member of the family to the use of that name
so that at the present time they could say that they and nobody
else could use it. He was satisfied that the ointment had been
made by others than those from whom the complainers had re¬
ceived their title, and had been sold by them from time to time
for a considerable period of years. Even the member of the family
from whom the complainers had derived their title had not shown
that he had the sole right either to the manufacture or sale of the
ointment under that name.
Lord Young, commenting on the question of who had been in
possession of or was entitled to the original recipe, said he did
not think it could possibly be of importance to anyone except a.
collector of old documents.
Interdict was therefore refused, and the ' respondent was found
entitled to additional expenses.
Theft from a Chemist. — At the Somerset Quarter Sessions
held at Taunton on Wednesday, January 6, Lawrence Hooper,
aged 20, described as a printer, of Weston-super-Mare, was
indicted for having stolen £10 belonging to Mr. William Henry
Webb, chemist, his master, at Weston-super-Mare on August 17.—
Prisoner pleaded guilty, and also acknowledged a previous convic¬
tion for felony. — Mr. Metcalfe prosecuted. — On August 17 last the
prisoner was in the employ of the prosecutor as a porter, and on
that date Mr. Webb sent him to get a cheque of the value of £10’
cashed at the Wilts and Dorset Bank. As Hooper failed to return
he sent to the Bank, and learnt that the prisoner had cashed the
cheque. Information was given to the police, and Sergeant
Richardson subsequently arrested the prisoner. — A sentence of six
weeks’ imprisonment with hard labour was passed.
Spirit of Nitrous Ether. — On January 4, Mr. Lemon,
High Street, Whitechapel, described as a chemist but not
registered as such, was summoned at Worship Street Police
Court for selling spirit of nitrous ether deficient in strength.
Defendant pleaded guilty, and in explanation said that the
spirit depreciated every time the stopper was taken from
the bottle, and also by long keeping. He had had the
spirit from which the inspector was supplied since April last,
and all the summer there was not much sale for it. — Mr. Corser
said there was no suggestion of adulteration, and under the
circumstances he thought that if the defendant paid the costs —
12s. 6 d. — the summons might be withdrawn. — The defendant at
once paid the costs.
How Teetotal Drinks are Made. — At the Sheffield Police Court,
on Jan. 5, two shopkeepers were charged with selling so-called tee¬
total drinks which contained more than 2 per cent, of proof spirit.
In the first case taken the evidence was to the effect that one of the
Jan. 16, 1897]
PHARMACEUTICAL JOURNAL
57
aissistant supervisors of Excise bought a bottle of herb beer, \yhich
was found to contain 4 3 per cent, of proof spirit, and a bottle of
•ginger beer, which contained 4 per cent. In support of the prose¬
cution evidence was given by Mr. C. H. Barge, of Somerset
House, showing that the herb beer contained a saccharine value
of 1034 ‘28, and the ginger beer a saccharine value of 1029 22.
Home of the ordinary beer sent out, said Mr. Barge, and sold in
public houses contained very little more spirit than the samples.
In 'both prosecutions the defendants were fined 10*. , and theBench
promised more severe treatment to other offenders.
Tincture of Rhubarb. — Edward Chambers, grocer, Soughton,
was summoned at the Northop Petty Sessions, on Thursday,
December 31, for selling adulterated tincture of rhubarb. — Supt.
John Jvor Davies stated that on December 4 he purchased three
ounces of tincture of rhubarb from defendant’s shop, for which
he paid Is. 3d. He divided it into three parts, one of which he sent
to the public analyst, who certified that the sample contained
25 per cent, of added water, and that there was no saffron in the
tincture as there should have been. — - Defendant said he was
ignorant of the adulteration, and that his wife bought the
tincture from Mr.. Barker, chemist, Mold. — Fined 1 8*. 9 d., includ¬
ing costs.
POISONING CASES AND INQUESTS.
Some Liniment was taken by Mary Ann Woods, of Norwich,
-causing her death. Five years previously she had made an
unsuccessful attempt to poison herself. At the inquest the medical
evidence showed that a fluid extracted from the deceased’s stomach
resembled a liniment contained in a bottle labelled as coming from
the Medical Institute. It was not in a special poison bottle. The
jury found “That deceased committed suicide by taking poison
whilst in an unsound state of mind.”
Chlorodyne was purchased by Mary E. Palmer from a chemist
at Folkestone, after quarrelling with a lady friend. She then
went to the rocks near the harbour and deposited her hat, tippet,
gloves, and the chlorodyne bottle on the rocks, where they were
found next morning. Later the body was discovered between the
rocks. Evidence was given to the effect that deceased was in the
habit of taking ehlorodyne for heart affection, and that there
was a severe blow over the right eye, caused before death,
probably by a fall on the rock, sufficient to render her insensible
.and to remain under the water until suffocated. A verdict of
“ Found drowned” was returned.
Morphine, taken by Isabella Wedge, the widow of a chemist
formerly carrying on business in Queen Street, Wolverhampton,
was the cause of her death, which occurred on December 5, 1896.
An analysis of the stomach revealed traces of morphine poisoning.
After medical evidence had been given as to the condition of the
deceased at the time of taking the poison, a verdict was returned
that ‘ ‘ Death was due to morphine poisoning, but there was no evi¬
dence to show under what circumstances the morphine was taken.”
An Embrocation was taken in mistake for medicine by Samuel
Thickett, at Bradford, on January 6. A police constable at once
rendered first aid, and administered the necessary emetics, and
the man soon recovered.
Overdose of Chlorodyne. — On Friday, January 8, an inquest
was held with respect to the death of Alfred William Salmon, 18,
draper’s apprentice, Newport. Evidence was given to the effect
that deceased complained of toothache on the previous day and
had purchased a 2*. bottle of chlorodyne, containing three ounces,
from a chemist. There were full directions as to its use on the
bottle, and he was twice warned not to take more than 15 drops as
a dose. The next morning he was found lying in bed uncon¬
scious, and quite two ounces had gone from the bottle, which
was properly labelled “Poison.” The Coroner said he thought
chlorodyne should be one of the medicines to be sold as a poison,
but it was not on the list ;* evidently deceased had inadvertently
taken an overdose to relieve his pain. No blame attached to
-anyone. The jury agreed, and returned a verdict accordingly.
This is another instance of insufficient knowledge on the part of a Coroner,
■ as chlorodyne contains a scheduled poison, and must therefore be sold under
the same conditions as a schedu ed poison.— [Ed., Ph. /.]
A correspondent, referring to this case, raises the question whether
the young man would have taken so large a dose had he not
obtained so much at such a low price.
Sulphuric Acid for Brandy. — Thomas Ward, 54, a retired
farmer, of 117, Wilton Road, Sparkhill, after being a total abstainer
for twelve months, commenced the new year by drinking brandy
to an extent not good for him, with the result that on Wednesday
morning, January 6, he told his wife he had taken poison in mis¬
take for brandy. Dr. Treston, who attended, found the man in a
most serious condition, death taking place at 11.30 a.m. A bottle
bearing the words ‘ ‘ Sulphuric Acid : Poison ” was produced at
the inquest, as having been identified by deceased prior to his
death as the bottle from which he had taken a quantity of liquor,
believing it to contain brandy. P. S. Harrison described the
shelves on which a number of bottles containing deceased’s horse oils
and a bottle of brandy were found, and pointed out that the bottle
in which the acid was found had a screw-stopper, which was not
the case with the brandy bottle. The Coroner thought it an ex¬
traordinary thing that a man should mistake one bottle for the
other, but it was possible that deceased had drunk himself into
such a condition as not to know what he was doing. “ Poisoned
by misadventure ” was the verdict.
NEW IDEAS.
[ Inventors and manufacturers are invited to submit specimens of
novelties, descriptive notices of which will be inserted for the tnjorma-
tion of readers of the Journal. Whenever possible, illustrative blocks
adapted to the width of the Journal columns should accompany the
particulars sent. Address : Editorial Department , 17, Bloomsbury
Square, W.C.j
MORE NEW TABLOIDS.
The more recent additions to Messrs. Burroughs, Wellcome,
and Co.’s list of tabloids include codeine tabloids, each containing
§ grain of the pure alkaloid ; tabloids of mercury with chalk and
opium, each containing 1 grain of grey powder, and f grain
of opium ; tabloids of blue and compound rhubarb pills,
containing equal quantities of blue pill and compound ^lubarb
pill ; compound iridin tabloids, prepared according to the follow¬
ing formula: ft Iridin, gr. 2; ext. hyoscy. , gr. £ ; pil. rhei co.,
gr- 4; compound colchicuna tabloids, each containing 1 grain of
acetic extract of colchicum and 1| grain salicylic acid ; pepsin and
strychnine tabloids, first formula : ft Pepsin, gr. 1 ; strych. sulph.,
gr. Y4- ; second formula : Ijf Pepsin, gr. 1 ; bism. subcarb. , gr. 3 ;
strych. sulph., gr. x4-
AN EXTRACT OF VEGETABLES.
The preparation known as “Fromm’s Extract” is claimed
to be made entirely from vegetable substances which,
after being ground to powder and mixed, are treated by
special machinery into which steam is introduced ; a vacuum
is then created, and all waste materials drawn off, leaving
the extract an absolutely pure nutrient. The whole of
the process is effected by machinery, none of the material being
touched by hand from the time it is introduced into the grinding
rollers until the extract is delivered from the last one ready for use.
The extract has a very similar appearance to that of meat extract,
and is used in the same way ; it is appetising, of agreeable taste
and smell, and a small quantity added to soups, gravies, jellies,
sauces, hashes, stews, ragouts, etc., greatly improves their flavour,
digestibility, and nutritive value. A small quantity of the extract
added to water which has ceased to boil, makes a most nourishing
soup or bouillon, and forms a valuable resource in all cases of ex¬
treme debility, as it is most palatable, and very easily digested.
Analytical reports show that the extract is very rich in flesh¬
forming constituents, fat, phosphates, chlorides, etc., part of
the nitrogenous matter being in the form of peptone and albu-
mose, whilst the digestive ratio of the food stuffs present is
exceedingly high. It seems therefore not too much to claim that the
extract is “a most nourishing article of diet, easily digested, and
forming a food of the utmost value and palatability.” It is
supplied in jars and bottles to retail at 7 \d., 1*. 1 d., and 2s., whilst
it is also manufactured in conjunction with all kinds of food for
the purpose of increasing their nutritive and digestive value,
including Fromm’s soup tablets (various), infants’ lacteal food,
baking flour, bread, biscuits, etc., and all kinds of anti-diabetic
preparations. The preparations are supplied wholesale only by
Fromm’s Extract Company, 61£> Fore Street, London, E.C.
58
PHARMACEUTICAL JOURNAL.
[Jan. 16, 1897
EXTRACTS FROM CONSULAR REPORTS-
Cultivation of Medicinal Herbs and Plants. — The consular
report for November on the Agriculture of the District of Batoum
states that an enterprising gentleman came from Russia Proper
about a year ago for the purpose of carrying out experiments in
the cultivation of medicinal herbs and plants in the Caucasus, and
at the same time to procure volatile oils. Pending the receipt of
the required permission from Government for carrying out his
proposed undertaking, he made researches in every direction for
this class of plants, and his labour, according to the Caucasian
agricultural newspaper, has been crowned with great success, he
having discovered a large variety of herbs which possess important
healing properties, the result being that he has received large
orders from many Russian firms of druggists. With a view to
encouraging the cultivation of the castor-oil plant, the Imperial
Bank has been authorised to make advances, at all its branches, on
the seed of this plant.
Otto of Roses. — Mr. Vice-Consul Wratislaw, reporting on the
trade of Eastern Rouiiielia, says it is probable that more land will
be put under rose cultivation as the production of grain becomes
less and less remunerative. But it is highly necessary that Govern¬
ment or other supervision should be instituted in order to insure
the purity of the otto exported, or European buyers would fight
shy of the Bulgarian article. ‘ ‘ Pure ” otto was offered last year by
certain firms at Kezanlik and Karlovo for 1200 fr. per kilo. , about
200 fr. less than what producers asked merchants for the un¬
adulterated article.
Olives. — Consul Hearn, in his report for November on the agri¬
culture and vintage of Cadiz, says the cultivation of olives is the
most important branch of the agricultural wealth of the distr ict.
The collection of this crop has just finished, and the result is most
deplorable. The olives are all worm-eaten and useless for pickling
or anything else. Last year’s crop of Queen’s olives was estimated
at 2,250,000 gallons, and it is not expected that this one will give
over 30,000 gallons of sound fruit. The gathering and preserving
of the oil-producing olives (Manzanilla) do not commence till the
end of November, and the result is certain to be analogous to that
of the eating olives (Queen’s).
Mexican Imports and Exports. — Consul Carden, in his
Annual Commercial Report on the trade of Mexico, states that the
imports of chemical products show a larger proportionate increase
in 1895 as compared with 1894 than any other group of articles, the
value returned being £304,000, as against £227,000, a difference of
34 per cent. In this trade England has only a very small share,
under 10 per cent. The United States supply nearly one-half, and
the remainder is furnished by France, and, in a lesser degree, by
Germany. The exports of dye-woods from Mexico amounted in
1895 to 93,936 tons, valued at £250,874, as against 70,169 tons,
valued at £183,600 in 1894. About 50 per cent, of the total exports
of dye-woods goes to England, about 20 per cent, each to France
and Germany, and the remainder to the United States. The
exports of vanilla have increased very notably in the past year,
the returns for 1895 showing a value of £135,330 against £86,449.’
for 1894. The whole crop, with the exception of a very small
amount sent to France, is exported to the United States. The
New York quotations show an average price of vanilla throughout
the year 1895 of from 5 to 8 dol. gold (£1 to £1 12s.) per lb., ac¬
cording to quality. The export price as given in the Mexican
official returns would appear, therefore, to be low, being at the
rate of little more than 16s. per lb.
i British Trade in Bulgaria.— Mr. McGregor, British Consul at
Sofia, in his report for November says, another article which was
formerly supplied by the United Kingdom, to the exclusion of all
other countries, but which now comes entirely from Austria, is
indigo, and the only reason that can be suggested for this change
is the want of readiness on the part of British houses to meet the
requirements of, or even to enter into relations with, would-be
customers.
NEW REMEDIES.
[ The notes given under this heading embody recent suggestions in
therapeutics. They cover both new drugs and preparations, and old ones
under new aspects. The word “ parts ” is used to represent parts by
weight, both for solids and liquids.']
Atropine in Diphtheria. — Elsaesser strongly recommends
atropine in the treatment of diphtheria, after testing its action in
350 cases. The prescription he employs is
R Atropini sulfurici . . . 3 milligrammes.
Cocaini hydrochlorici . 5 centigrammes.
Aquas amygdal. arnar . 20 grammes.
M.D.S.— Every hour a drop for every year of the child’s age.
For adults he recommends 10-15 drops, according to the constitu¬
tion and state of the disease. He regards it of the greatest im¬
portance that the medicine should be given regularly every hour,
day and night. Gargling with potassium chlorate or ol. terebinthinae,
with good wine to drink, is also recommended. Tire drops are best
taken on sugar, or in a spoonful of tokay. — Therap. Mmiatsh. , x. , 471 .
Enema of Quinine in Whooping Cough. — As a substitute for
sublimate painting in whooping cough, Schulze recommends the
use of an enema of quinine bisulphate in distilled water, the dose¬
being 1 centigramme for every month, and 1 decigramme for every
year of the patient’s age, the limit of 50 centigrammes not being-
exceeded even in the case of older children. A clyster of this-
strength is given three times daily. No disadvantages have
resulted, and a cure is generally effected in eight days, although it
is advisable to give one enema per diem for another eight days to
guard against relapse. In certain cases a suppository may be
substituted for the enema, but the author finds that the fluid injec¬
tion acts more promptly. — Munch. Med. Woch., xliii. , 859.
Extract of Helianthus Annuus in Malaria. — As a substi¬
tute for quinine, which is difficult to administer to young children,
Moncorvo has found the alcoholic extract of the flowers and leaves
of Helianthus animus, the common sunflower, to have a prompt and
general anti-malarial action. The dose given was from one to six
grammes in the twenty-four hours. No bad after-effects were
observed, but in a few cases, which were also intractable to-
quinine, the result of the helianthus treatment was not satis¬
factory.- — Pediatrics, ii., 287, after Rio de Janeiro Centralblatt f.
Therap.
Tannigen in Diarrhoea. — Reviewing the published literature of
tannigen and recording his own practical experience, Hirschberg
considers the new compound to be extremely valuable in the treat¬
ment of diarrhoea, particularly in infantile patients. For these
the dose is 20 to 30 centigrammes four times daily ; to adults, off
centigrammes may be given for a dose in a cachet. Infants take
the powder best mixed with some pleasant vehicle, since it is-
without taste it is easily given. The precaution should be taken
to give a cupful of milk about an hour before the dose to prevent
the decomposition of the tannigen in the stomach. The few cases
of vomiting after the administration of the drug are probably due
to the omission of this precaution. Tannigen is particularly bene¬
ficial in chronic diarrhoea, both in infants and adults ; in cases of
rachitis with this complication the effect is very notable. In adults-
the author obtains the best results with a mixture of equal quan¬
tities of tannigen and betol. — Rev. de Therap., lxiii. , 618.
Sodium Chlorate to Counteract Iodism. — In a case of marked
intolerance to iodide of potassium in an old syphilitic, Calomeno-
poulo found that all the objectionable symptoms vanished when
the iodide was combined with sodium chlorate, 90 grains of the
latter salt being given each day ; under these circumstances the-
patient was able to take 45 grains of potassium iodide for forty
days without inconvenience, but developed acute symptoms of
iodism when the chlorate was omitted, even with a diminished dose-
of the iodide. — Therap. Gaz. [3], xii. , 613, after Joum. des Tracts-
Zinc Oxide and Belladonna in Whooping Cough. — The-
following combination is recommended (./ ourn. des Practiciens) for
pertussis : — Powdered belladonna, 15 grains ; oxide of zinc,
15 grains ; extract of wild thyme, 30 grains. Make into forty
pills, and give from one to six pills per diem. — Therap . Gaz. [3],
xii., v 618.
Jan. 16, 1897J
PHARMACEUTICAL JOURNAL.
59
CORRESPONDENCE.
All Articles, Letters, Notices, and Reports Intended for
publication in the Journal, Books for Review, and com¬
munications respecting editorial matters generally)
must be Addressed “editor, 17, Bloomsbury Square,
London,” and not in any case to Individuals supposed
to be connected with the editorial Staff. Communica¬
tions for the Current Week’s Journal should reach the
Office not later than Wednesday, but news can be Re¬
ceived by Telegraph until 4 p.m. on Thursday.
The Regulation of Prices.
Sir,— A correspondent appeals to “the fathers of the trade” to
help the P. A.T. A. , whatever that may mean. The presumption of
-answering for the “ fathers,” or for anybody else, be far from me,
who still lack a few years of half a century in the business ; but
perhaps I may make an observation or two. In many things the
fathers of the present day, instructed by their richly endowed
children, are content to stand aside and watch the arena until they
are called upon to hang their somewhat rusty and obsolete arms in
the temple. Old-fashioned principles have grown familiar to them
and form part of their nature. If they do not grow wiser they
may grow more crafty, desiring new experiments to be made in the
roverbial direction. The other day I found a new Yankee notion
eing tried upon me in the shape of an invoice for unordered goods,
with wonderful liberty in the terms of payment. I have an old-
fashioned predilection for ordering what goods I want. I
refused to take the parcel in, and the postman took it away.
I am more than haunted, I am possessed by an old ghost of* a
notion that when I buy and pay for goods they are absolutely my
own to do what I like with, subject to such laws as Parliament
may make respecting their sale and disposal. But now I find a
new principle introduced, which I call conditional buying. The
conditions on an educated body, according to my ancient faith,
should be those of honour ; and it is an indignity to be called upon
to sign an agreement to act honourably. Would any man buy a
horse of his friend with a guarantee in writing that he would treat
it well? But I am beginning an essay on ethics when I only
meant to say that some of us older ones have more confidence in
following sound principles of political economy, though they may
seem to be temporarily inconvenient than in “going for” the gold
that glitters. The subject would run over many of your pages if it
.got loose.
January 9, 1897. Junior Senex (75/6).
Sir, — I, too, like Mr. Barrett, would like to know how it is our
“ fathers in the trade ” do not take sides with the retail dealers,
and do what they can to assist us in obtaining a living profit on
the specialties in which they are interested. They may possibly
be like Evans, Sons, and Co. , waiting and watching. I know only
too well from extensive experience that the average chemist and
druggist is a cold, unsympathetic sort of individual, who expresses
his dislikes freely, but will not exert himself one little bit in the
way of combination, even when it is to better his own position in
the near future. A paltry five shillings per annum is all that is
asked by the P.A.T.A. , a trifle over one penny per week, which is
returned even now many times a day, if he has any business at
all. Surely, sir, it is high time this waiting and watching atti¬
tude came to an end, both by the makers and the distributors.
Much has been done by the few faithful ones, and more still can
be done if each chemist will only do his duty. We also want
the assistance of energetic men who will canvass, each in his
own district. It must not be expected in large districts like
the Midlands, that the Honorary Secretary of the Trade Com¬
mittee can spare the necessary time ; it is therefore imperative
that more help in this direction be forthcoming. Information
of any underselling of the P.A.T.A. list should be given to
headquai'ters, or the Local Trade Secretary. Trial purchases
would then be made, and supplies stopped if the offender will
not listen to reason, which I am pleased to sav he invariably
does. We are frequently told that a certain article can be bought
from so-and-so at such a price, though on investigation it is not true.
The thanks of the trade are due to you, Mr. Editor, and to the
other trade journals who have given valuable assistance. It only
remains for the “fathers” to join hands with the “children” of
the drug1 trade to ensure positive and complete success.
. Birmingham, January 12, 1897. Chas. Thompson.
Chemists’ Eederation.
Sir, — I was pleased to see Mr. Foulston’s letter on “ federation ”
as a remedy for the “ patent medicine ” difficulty. I hope chemists
will now shake themselves up and keep up a good discussion in the
Journal and amongst themselves, to weigh the advantages and
disadvantages of such a scheme, which might also be applied to
the wholesale supply of other chemists’ requisites. A similar
scheme was advocated by me last April, but apparently only one
chemist found it worth while to write to the Journal on it, although
many wrote direct. If only chemists could be brought into line
on the subject I believe it would revolutionise their
trade in the right direction. The P.A.T.A. is very good in its
way, but as the public have already become accustomed to
get “patents” at practically cost prices, I fail to see how
the proprietors as a whole can now raise them to
secure the retailer more than a 10 per cent, or so profit at the
outside. The P.A.T.A. has undertaken the correlation of too
many interests in my opinion. It appears to me that the chemist
is rapidly drifting into the position of a mere distributor of
branded goods, on which he can make only a 10 per cent, or so
profit — the bulk of the profit on them being made by the proprie¬
tors, who in many cases are unconnected with his trade. Will
the chemists kindly reflect on the influence that branded com¬
pressed drugs will, in the near future, have on their business ?
Anyone who has had hospital experience and constant intercourse
with medical men will know what a hold these are getting, and
how they tend to render the skilled chemist unnecessary. These
also in the future will drift into the position of “ patents,” bearing
the same miserable rate of profit. How much better it would
have been for chemists to have got not only the retail profit but
the wholesale profit also pro rata. Our energetic new counsellor
Mr. Park who, I should think from the tone of his letter in the
Journal, is in favour of such a scheme, could not do better than
bring the -matter before his local association at an early date to
sift the matter out and report the result. If the fashion were once
set, other associations would probably follow suit. In short,
the movement now wants an influential leader. Trusting
chemists will not let this occasion slip of airing their views on this
important subject,
New Gross Gate, S.E., January 11, 1897. G. T. Cooper.
Botanical Specimens for Students.
Sir, — I should be glad to forward, post paid, to one or two
students at the Pharmaceutical Society’s Schools, any number of
botanical specimens during the coming course of lectures. I can
give the genus of most indigenous local Phanerogams, and the
more common genera of the algae (fresh water) ; but only a few
enera of fungi, musci, hepatic*. Also, besides plants for classi-
cation, plants with members differentiated, so as to be of use in
the study of the morphology of members generally. Also organs
and members at interesting stages of development for histological
study. In return I should be glad if they would give me the bare
outline of the lectures on botany, and occasionally identify a plant
for me, and give me the benefit of any interesting notes they find
time to insert. I read Vine’s ‘ Students’ Text-Book.’ Shorthand
notes would save time.
Bedford, January 8, 1897. Lewis Amb. Roberts.
*** We are always prepared to Identify suitable specimens sent in good con¬
dition by readers. — [Ed., Ph. /.]
“Sweet Lavender.”
Sir, — Our attention has been called to a paragraph which
appeared in several of the daily papers last week relative to the
lavender industry of Hitchin and Mitcham. We are, of course,
ignorant of the source from which the writer obtains the informa¬
tion upon which his remarks are based, but we feel bound, as one
of the largest and oldest firms of growers and distillers of lavender
in Hitchin (the lavender industry having been carried on by us
and our predecessors for upwards of a century) to protest against
the remarks as being misleading and contrary to the facts. In our
opinion no artificial concoction can so far successfully compete
with the natural product as to threaten with extinction or even
curtailment the lavender industry of Hitchin and Mitcham.
Indeed, so far as we personally are concerned, the demand
for the genuine article increases rather than diminishes year by
year. It is perfectly true that the severe frost of two years ago
did considerable damage to the crops both here and at Mitcham,
but the plants have now recovered from its effects, and we have
60
PHARMACEUTICAL JOURNAL-,
[Jan. 1G, 1897
every reason to look hopefully to the future. In conclusion we
may mention that, so far from entertaining the pessimistic views
attributed to growers by the writer, we. are contemplating putting
even a much larger acreage under cultivation than we at present
possess.
Hitchin, January 11, 1897. Perks and Llewellyn.
The Students’ Page.
Sir, — Permit me to second the remarks of a “ British Student,”
and to offer a ceacl mille failthe to “ The Students’ Page,” which I
am so glad to see inaugurated. As an encouragement to other
students, I send your publishers half a guinea, thus becoming a
semper reader of your pages instead of a quondam one. Would you
kindly state in a foot-note how an Irish student can become a
registered student of the Pharmaceutical Society, in order that he
may have access to the Library ?
Belfast, January 11, 1897. Ulster Student.
*#* The only way in which anyone can become a Registered Student of the
Pharmaceutical Society is by passing the First examination or its
equivalent, and then applying to be elected. Apply to the Registrar, IT,
Bloomsbury Square, W.C., for a list of the bodies whose certificates are
accepted in lieu of the First examination.— [Ed. Ph. J.]
Sir, — In my opinion every alteration that has taken place in the
Pharmaceutical J ournal has improved the same, and not the least
the latest, viz., “ The Students’ Page.”
Carnarvon, January 12, 1897. J. Jones.
Sir, — There seems to be some confusion in your account of
Professor J. Bretland Farmer and Mr. Lloyd Williams’ investiga¬
tions of the fertilisation of fucus ( Ph . J., January 2, “Year’s
Botany,” p. 15). I have learnt from Vine’s manual and other
works that the female organ among the thallophytes is never an
archegonium, and that that of fucus — the particular case in point —
is an oogonium. Secondly, I have always understood that the
oogonia rupture, their oospheres becoming extruded. Thuret’s
research, as I understand it, proved that the oosphere after libera¬
tion became surrounded by the spermatozoids, hence the oogonium
itself, if this be so, can scarcely be said to be fertilised. I gather
from your article that the actual fusion of the gametes, which
Thuret was unable to observe, has now been seen by Farmer and
Williams. I may, however, be entirely wrong in my rendering of
the matter, and if so should be glad to be set right. Several
students have expressed to me their appreciation of ‘ ‘ The Students’
Page ” so recently introduced, and these sentiments I can heartily
re-echo.
Exeter Technical College, January 10, 1897. Alan H. Ware.
*** Our correspondent is thanked for his correction. In the passage referred
to the word “archegonia” should be replaced by “oospheres.”—
[Ed., Ph. /.] _
ANSWERS TO QUERIES.
[Queries addressed, to the “ Editorial Department, 17, Bloomsbury
Square, W.C.,” will be replied to in the Journal as early as possible
ajter receipt, but the Editor cannot undertake to reply to them
through the post, nor is it always possible to publish answers the same
week. Questions on different subjects should be written on separate slips
of paper, each of which should bear the sender’s name or initials.
Readers requiring working formulae for special preparations, and
■intimating their wants to the Editor, will be assisted as far as may be
practicable. The word “parts,” when used in fop mules, invariably
indicates parts by weight. Anonymous queries will be ignored .]
Medical Specialist. — We cannot undertake to recommend
medical practitioners. [Reply to J. K. — 74/36.]
Pharmaceutical Preliminary. — No, the standard of the exami¬
nation is so low that the certificate would not be accepted in lieu
by any other examining body. [Reply to H. H. — 75/23.]
Deer Suet. — Prepared lard, 10 ounces ; veal suet, 10 ounces ;
olive oil, 2 ounces ; palm oil, 1 ounce ; French oil of lavender, 30
minims ; or any other perfume to desired odour. Melt the fats,
remove from the source of heat and add the perfume.
[Reply to Country Man. — 74/37.]
Botanical Specimens. — (1) Alchemilla arvensi.% Scop. (2)
Rhamnus purshiana. (3) Specimen insufficient for identification ;
send a leaf. [Reply bo Wood. — 75, 19.]
Sodium Fluoride. — Under the name of fluorol, sodium fluoride-
has been introduced into medicine by Duclos ; it is used as an
antiseptic in f per cent, and 1 per cent, solutions (see Ph. J. [4],
ii. , 33). [Reply to J. A. — 74/8.]
Hair Dye. — Except for your bashfulne.su in refraining from ap¬
pending your name to the query, it might be doubted whether-
anything would injure your skin. Note that anonymous queries
cannot be attended to. [Reply to W. I. J. — 75/20.]
Bear’s Grease. — Soft veal fat, 15 ozs. ; palm oil, 1 oz. ; essence
of bergamot, 30 minims ; oil of cintronella, 10 minims ; coumarin,
10 grains. Melt the fats together on a water bath, when nearly-
cold stir in the perfume. [Reply to Country Man. — 74/37.]
Poultry Spice to Make Fowls Lay. — Coarsely powdered
oyster shells, 1 lb. ; dried sulphate of soda, 8 ozs. ; dried sulphate
of iron, 8 ozs. ; gentian root in coarse powder, 8 ozs. ; powdered
black pepper, 8 ozs. ; powdered cummin, 8 ozs. ; powdered
capsicums, 2 ozs. Mix. [Reply to Country Man. — 74/37.]
Prescription Difficulty. — This is evidently intended to be:
dispensed at some hospital or dispensary where alone the
strengths of the solutions are known. “Sol. cocain. fort., ^ii.,”
and “sol. atrop. fort., Jii.,” appear to be the ingredients of the-
drops. [Reply to C. W. R. — 73/36.]
Dr. Begbie’s Mixture. — This is composed of dilute hydro¬
cyanic acid, 30 minims ; dilute nitric acid, 3 fluid drachms ;
glycerin, 1 fluid ounce ; infusion of quassia, up to 6 fluid ounces.
Dose. — One tablespoonful three times a day. We are making
inquiries about the pills. [Reply to Associate. — 73/29.]
Collodion. — The B.P. preparation is not suitable for photo¬
graphic purposes, though it might serve for rough experiments.
This you can ascertain for yourself. To prepare photographic
collodion, dissolve pyroxylin, 5 grains, in alcohol (s.g. 0-820),.
| ounce, and ether (s.g. 0'725), § ounce. Both alcohol and
ether may be methylated. [ Reply to Zanoni. — 75/5.]
Preparation of Boroglyceride. — You must not look upon
Martindale as an infallible guide, or you may be led astray..
To prepare the boroglyceride, take boric acid, 62 ; glycerin, 92.
The glycerin should first be heated in a tared porcelain dish over
the naked flame to a temperature not exceeding 300° F. ; then add
the boric acid in successive portions, constantly stirring. When
all is dissolved continue the heat at the same temperature,
breaking up the skin which forms on the surface until the weight
is reduced to 100 parts. Then pour out on to a flat slab, previously
wiped over with a rag made slightly greasy with vaselin ; when
cool cut the boroglyceride into pieces and keep in stoppered
bottles. [Reply to Associate.— 75/9.]
Dr. Lo wes’s Pure Water Test. — This test is described in a
price-list published by J. J. Hicks, Hatton Garden, E.C., as a.
simple but effective method of treating the purity of water, by
Nessler, “derived from sewage water (sic) placed in small glass
bulbs hermetically sealed.” The precaution of hermetically sealing
up the sewage water is a wise one, particularly as the bulbs are
recommended for use in households. Why, however, the presence
in a house, of bulbs containing sewage water is “specially valuable”
in “ hot weather,” as is stated in the list, does not appear. Pre¬
sumably it is to be understood that the bulbs actually contain
Nessler’s reagent, but it must be pointed out that this is a most.
unsatisfactory test for the purity of water. If the water be hard
the test cannot be relied upon, and in most cases it is abso¬
lutely necessary to distil the water before adding the reagent.
[Reply to T. L. B.— 72/27.]
COMMUNICATIONS, LETTERS, etc., have been received from
Messrs. Bechhold, Bennett, Blackburn, Bullivant, Clague, Cocks,
Cooper, Crampton, Deacon, Gibson, Green, Hogg, Jackson,
Johnston, Jones, Kenway, Llewellyn, Lloyd, Parsons, Perks,
Pollard, Prosser, Ransom, Reynolds, Roberts, Standage, Thomp¬
son, Walker, Wanner, Ware, Wilson, Woolldridge.
PHARMACEUTICAL JOURNAL.
61
Jan. 23, 189J>]
ON THE SEPARATION OF NITRATE OF COPPER FROM
NpTRATE OF SILVER IN THE MANUFACTURE
OF CAUSTIC.
!-• . JC'l
. EY C. J. IJ.: WARDEN,
\ . ! - > - • 5 a 7/" rjr
Corresponding Member of ine Pharmaceutical Society.
So far as I am aware, i-^ is^et generally known that strong
nitric acid precipitates pitrat^jOf silver from concentrated aqueous
solutions, and this action Tias been utilised in the manufacture of
lunar caustic at the Calcutta Medical Depot. The silver employed
always contains a certain amount of copper, and after solution of the
metal in nitric acid and separation of the gold, as much as possible
of the nitrate of silver is crystallised out, and the deep blue mother
liquor evaporated to dryness. The dry salt is then powdered and
placed in a glass funnel stopped with a plug of asbestos, and perco¬
lated with strong nitric acid, sp. gr. 1 ’42. The nitric acid
dissolves the whole of the nitrate of copper, leaving the nitrate of
silver perfectly white, while only a very small amount of silver
nitrate is dissolved. The nitric acid can of course be recovered by
distillation, and the small amount of nitrate of silver separated
from the nitrate of copper by precipitation with salt, and when
sufficient has accumulated reduced to the metallic condition by one
of the usual methods. In preparing nitrate of silver by crystallising
out the salt, a point is reached when the mother liquor is too
highly charged with nitrate of copper to permit of a sufficiently
pure silver salt separating by crystallisation, and this impure or
“ blue nitrate of silver ” has hitherto been returned to the Mint.
By the adoption, however, of the method above described these
residues can be worked up and nearly the whole of the silver
obtained in the form of nitrate, and as the nitric acid can be
recovered the process is decidedly economical, while it affords a
salt practically free from copper.
ON THE APPARENT ACTION OF LIGHT IN INDUCING
CRYSTALLISATION OF STANNOUS IODIDE.
BY C. J. H. WTARDEN,
Corresponding Member of the Pharmaceutical Society.
About six years ago, while at the Medical College, Calcutta, I
prepared some stannous iodide by acting on stannous chloride with
iodide of potassium, the salt being preserved in a stoppered
inverted flint glass specimen bottle in a moist condition. The
bottle was placed in a glass case with glass doors in front and
behind, painted white inside, and about three feet from a window
facing W, with a fan-light above, but the window was generally
closed by Venetian shutters ; as a rule, only diffused light entered
the room. After the stannous iodide had been in this position for
some time, I observed that that portion of the salt facing the
window was coated with ruby coloured needles, while the iodide
at the back and sides of the bottle was still apparently amorphous-
The bottle was shaken up, and a piece of thin white paper
cut in the shape of a cross was gummed by the top of the cross to
the bottle, which was then replaced in the glass case, with the
cross opposite the window. After some weeks that portion of the
contents not protected by the cross was coated with ruby needles,
while the salt behind the paper cross was apparently amorphous.
A few months ago I asked Professor A. Pedler, F.R.S., to have a
look at the specimen, and he informed me that its condition was
unchanged, the portion of the iodide protected by the cross being
non-crystalline, and having the shape of the cross accurately
marked, while the rest of the front of the bottle was covered with
ruby needles. The difference in appearance between the
Vol. LVIII. (Fourth Series, Vol. IV.). No. 1387.
ruby crystals and the dirty yellowish hue of the salt covered
by the cross being most striking. According to Roscoe and
Schorlemmer,* stannous iodide is readily soluble in warm
solutions of the chlorides and iodides of the alkali metals,
and also in dilute hydrochloric acid. I cannot now remem¬
ber whether the salt I prepared was thoroughly washed, or
the mother liquor merely drained off before it was placed in the
bottle. If it was not washed, chloride of potassium and free
hydrochloric acid would be present, and the stannous iodide might
have been dissolved and slowly crystallised out on the front of the
bottle, which was exposed to a slightly higher temperature than
the back : but then it is hardly possible that a thin piece of paper
could have intercepted the heat rays, and prevented solution of
the salt in those portions which it covered ; and besides the period
now— -about five years— during which the specimen has been ex¬
posed, would appear to militate against the view that heat was the
factor which induced the phenomenon. On the other hand, if
light induced the crystallisation, the thin white paper could
hardly have intercepted all light rays, especially when the duration
of the experiment is remembered. Be the explanation what it
may, the phenomenon is strikingly interesting and worth investi¬
gation : while for lack of a satisfactory explanation, I have
ascribed it to the apparent action of light.
JOHN DALTON AND THE ATOMIC THEORY. f
BY W. A. COCKSHOTT.
John Dalton was born at Eaglefield, a small village near Cocker-
mouth, in Cumberland, in September, 1766, of parents belonging to
the peasant-farmer class, known in the Lake District as “states¬
men,” noted for their sturdy independence and simplicity of life.
Dalton’s father was a Quaker, and by trade a hand-loom weaver,
which occupation, though only yielding him a scant income, enabled
him to send his son to school until the age of eleven, by which
time he had gone through a course of mensuration, surveying, and
mathematics, thanks to an appreciative schoolmaster, who recog¬
nised his pupil’s talent and respected his dogged perseverance. In
addition to securing the interest of his schoolmaster, young Dalton
found a patron in a neighbour, a Mr. Robinson, who had given
much attention to meteorology and was, for the times, a very
capable scientist, and moreover a correspondent of Benjamin
Franklin. By the encouragement and help he thus obtained
Dalton, at the early age of twelve, was in a position to open
a village school as principal, which occupied him for two
years, when he turned to farming, still pursuing his -studies,
however, under the friendly guidance of Mr. Robinson. After four
years he joined his elder brother, who was a schoolmaster at
Kendal, where he remained twelve years, finding in a blind gentle¬
man of the name of Gough a friend of similar tastes and views,
who induced him to make a collection of the Kendal flora, which
still exists and is accessible in one of the Manchester libraries.
The meteorological observations and studies of Dalton, commenced
in 1787, and continued by him until the evening before his death
in 1844, a period of fifty-seven years, comprising a total of 200,000
separate observations, are a convincing proof of his perseverance
and methodical habits. During his residence at Kendal, Dalton
delivered several courses of lectures on Natural Philosophy,
which attracted attention to his capabilities as a teacher, with the
result that in 1793 he was appointed Lecturer in Mathematics and
Natural Philosophy to a Nonconformist college in Manchester,
where he stayed six years at a salary of £S0 per year. In addition to
Treatise on Chemistry,’ vol. ii. , part 2, p. 242. _
fLecture delivered before the Liverpool Pharmaceutical Students’ Society
62
PHARMACEUTICAL JOURNAL.
[Jan. 23, 1897
this, he continued to deliver public lectures and to give private
lessons, and, as a member of the Manchester Literary and Philo¬
sophical Society, communicated at its meetings most of his original
work in the form of papers. One of his most remarkable papers
was his first, delivered in 1794, “On Some Extraordinary Facts
Relating to the Vision of Colours,” in which he gave a critical
account of his colour sensations, for he was himself “ colour¬
blind,” and was one of the first to draw general attention to this
disease, and to study the subject in a thorough manner. Hence
the term applied to this defect — Daltonism.
At this point it would be as well to shortly sketch the history of
the Atomic Theory. The earliest name associated with the theory
is that of a Greek, Leucippus, whose works are lost and whose
teachings would be so as well but for the incidental references of
other ancient authors, such as Democritus (erroneously called a
pupil of Leucippus), who beyond question deserves the credit of
originating the theory. This was most unpopular with Greek
philosophers, and was generally referred to with contempt, Aris¬
totle even rejecting it, and the weight of his name was enough to
dispose of it for many centuries. Some 100 years after Democritus,
Epicurus developed and added to the theory, being credited with
great penetration in reviving and preserving to the world a theory
in his own time scouted as absurd. Only a few fragments of his
works remain, and with these exceptions all the works of these
ancient philosophers are lost. A poem by Lucretius, who lived
b.c. 99-55, fully describes the theory which has been adopted by
modern scientists. This poet, whose works were much admired
by Shelley, whose peculiar views they undoubtedly influenced, has
been called the atheistic and materialistic poet, the object of his
poem being “the demonstration of the importance of the Atomic
Theory as a means to enable a man to live his life free from the
crushing pressure of superstitious fears.” In the opening sentences
of the poem he states that : — -
“ When human life lay shamefully grovelling upon earth, crushed down under
the weight of Beligion, who showed her face from heaven frowning upon
mortals, from on high with awful aspect, a man of Greece was the first who
ventured to lift mortal eyes to her face, and the first to withstand her
openly.
The universe is described as atom* and void, the atoms being
hard and solid, an idea retained by recent chemists, though
Professor Clifford says : —
“Modem chemists explain the hardness of solid matter by the very rapid
motion of something which is infinitely soft and yielding.”
Essential properties and secondary qualities are sharply distin¬
guished by Lucretius, who separates the intrinsic and essential
qualities, such as form, size, weight, etc., of atoms from the
secondary evanescent qualities ; for example, he says all colours
are perishable, therefore the atoms are not coloured. Neither in
the same way have they sound, scent, warmth, or cold. All such
things are perishable, and must be withdrawn from the first
beginnings (atoms) if we wish to assign for existing things
imperishable formations. The best known dictum of Lucretius,
which he asserts frequently in the course of his poem, is that
“nothing is ever begotten of nothing,” but that what each thing
can and cannot do is absolutely decreed. All his laws of Nature
are constant and unchanging, all phenomena follow some well-
defined law or laws, and nothing happens without a cause, or in
other words, nothing happens but what can be accounted for
without supernatural agency.
From the time of Lucretius until the seventeenth century there is
a long blank, and we hear nothing of atomic theories until Gassendi
revived those of Lucretius, and it was probably his influence which
converted Robert Boyle and Sir Isaac Newton, and made them such
pronounced atomists. Boyle suggested that the various atoms
differed in form, and that when two substances did not act chemi¬
cally upon one another the forms of their respective atoms were in¬
appropriate for doing so. A quotation which particularly in¬
fluenced Dalton at an early date, taken from the works of Newton,
will explain his views : —
“ It seems probable that God in the beginning formed matter in solid, massy,
hard, impenetrable, moveable particles of such sizes and figures, and with
such other properties, and in such proportion, and as most conduced to the
end for which He formed them, and that these primitive particles being
solids are incomparably harder than any porous body formed of them, even
so very hard as never to break or tear in pieces. While the particles con¬
tinue entire they may compose bodies of one and the same nature and
texture in all ages, but should they wear away or break in pieces, the
nature of things depending on them would be changed, and therefore that
nature may be lasting. Compound bodies (are) apt to break not in the midst
of solid particles, but where those particles are laid together and only touch
at a few points.”
From these principles it will be seen that all material things seem
to have been composed of the hard and solid particles above men¬
tioned, variously associated in the first creation by the counsel of
an intelligent agent.
A number of valuable manuscript notes, laboratory note-books,
notes for courses of lectures in Dalton’s handwriting have been
found in the Library of the Manchester Literary and Philosophical
Society by Sir Henry Roscoe, which help us in observing the steps
in the mental process which led Dalton to the conception of the
Atomic Theory. Other scientists, such as Boerhaave and Van
Helmont, held the Newtonian theory of atoms, but they were
exceptions, for the general opinion was that matter was continuous
and not composed of atoms. This may be illustrated as follows : —
Previous to the discovery of C02 the atmosphere was supposed to
take up the water in solution, and the air and aqueous vapour existed
together in such a way that the smallest conceivable particle
of the atmosphere would contain a certain proportion of aqueous
vapour, and a certain proportion of air, that is to say the air and
aqueous vapour had become a part of each other. This was the
doctrine of chemical solution. On the subsequent discovery of C02, 0
and N the same view of their constitution was held, and in the least
possible portion of atmosphere 0,N,C02 and water were said to exist.
During his residence at Kendal, Dalton, in his volume on meteoro¬
logy, concluded one of his essays by stating that in his opinion
the aqueous vapour in the atmosphere existed separately from the
air, or in other words he negatived this generally received theory
of chemical solution, which was then applied to all bodies, solid
and liquid. Just one hundred years ago Dalton, then thirty years
of age, was attending classes in chemistry, held by Dr. Garnet, and
from this date to 1810 his best work was done. Prior to this he
had confined his researches to the physical constitution of the
atmosphere. At that time the phlogistic theory was not yet
thrown over; Black, Priestley, and Cavendish still stubbornly held
their views, notwithstanding that the work of Lavoisier (who had
been guillotined in 1794) had practically given this theory of phlo¬
giston its death blow. Lavoisier’s theory of combination only
partially replaced the general theory of phlogiston and was but of
limited application, so that chemistry just then was without any
definite theoretical basis. In the year Lavoisier died, Richter
published a work on chemistry, giving the proportionate weights in
which bases and acids united, clearly indicating that he perceived
the law of combination in reciprocal proportions, but not giving
forth his conception of any atomic theory nor showing any know¬
ledge of the law of multiple proportions.
This work of Richter’s did much to excite Dalton’s views as to
the Atomic Theory, and was the means of Berzelius undertaking
the investigation of the combining weights of bodies. Inde-
Jan. 23, 1897.]
PHARMACEUTICAL JOURNAL.
63
#
pendently of Richter’s wo rk, Prout did much of a similar cast
arriving at the same conclusions as Richter, and like him failing
to see the relationship of the multiple proportions. Both Prout and
Richter were mathematicians rather than chemists, and instead of
expending their ingenuity in elaborating an atomic theory, used
all their energy in trying to arrange the combining numbers of bases
and acids in some kind of mathematical series. One of Dalton’s
contemporaries, Berthollet, though not holding the atomic theory,
threw over the phlogiston theory, and held that chemical affinity
and the laws of attraction discovered by Newton in astronomy
were only different manifestations of the same force : that sub¬
stances did not always combine in definite fixed proportions, but
that in this there was a latitude within which they did so.
As Wurtz says of the theories of chemistry up to this date,
“ they were isolated and without connection, and it was reserved for an
English chemist to complete them by a discovery of the first order and to
arrange them by an hypothesis at once simple and fruitful.”
Going back to Dalton’s chemical studies, he continued his
researches on gases, and to the law relating to the expansion of
gases by heat he certainly deserves to have his name attached, as
he was the first to give it, and not either Gay Lussac or Charles
Papers on the atmosphere, containing the first observations on the
law of multiple proportions ; on the solubility of mixed gases,
given in conjunction with one by Dr. Henry, the originator of Henry’s
law relating to the solubility of gases in water when under pressure,
were read by Dalton in Manchester. How Dalton came to apply the
combining weights to atoms we know not, yet that is the very point
to which science is so much indebted to him. The results of Dalton’s
work were published by him in his ‘ New System of Chemistry.
A claim was put in for one Dr. W. Higgins as the inventor of the
Atomic Theory by Sir H. Davy in 1815, and Dalton was stated to be
simply a plagiarist, but the claim would not stand, and, as Wurtz
says, Higgins’ conception was spoilt by errors and contradictions, so
that it is useless to represent him as one of the authors of the
Atomic Theory. This honour belongs to Dalton and Dalton alone.
Honours fell thick upon Dalton towards the end of his life.
He was elected an F. R. S. , received the first Royal medal, became a
corresponding member of the French Academy, had the Oxford
honorary degrees of D.C.L. and LL.D., and received a pension from
the British Government of £150 per annum. In addition to these, a
statue to his honour was placed before the Manchester Town Hall
by public subscription, and a bronze replica opposite the Infirmary.
After his death his name was perpetuated by the city in the Dalton
Mathematical and the Dalton Chemistry Scholarships. He died on
the morning of July 28, 1844.
Further Notes on Tannoform. — De Buck and De Moor have
given tannoform an extended clinical trial, employing it both ex¬
ternally as a dressing, or as a diapasm, or internally. In various
forms of skin diseases a dusting powder — composed of French
chalk, 4 parts ; tannoform, 1 part — has given excellent results. In
cases of hyperidrosis the direct application of tannoform has given
immediate relief and ultimately effected a cure. In impetigo the
following ointment, applied twice daily, effected a complete cure
in four days : — Tannoform, 3 parts ; vaseline, 10 parts ; lanoline,
20 parts. Acute eczema of the breasts yielded in fifteen days to
the application of tannoform, 1 part ; starch powder, 5 parts. In
eczematous impetigo of the ears and face cure in eight days was
effected with tannoform, 3 parts ; oxide of zinc, 6 parts ; vaseline,
30 parts. In infantile diarrhoea tannoform was given internally,
in daily doses of one gramme, divided into four doses ; it acted
promptly and effectually. — Rev. de Thfrap. Med. Chirurg., lxiii.
586, after Bdg. Med.
PRACTICAL RADIOGRAPHY.
III.— THE TESLA COIL.
This coil, which is known also as the disruptive coil, takes its
name from the discoverer, Nikola Tesla, who by its aid produced
a great number of highly interesting phenomena in connection
with electric currents of high frequency of alternation, and high
voltage or pressure. These currents have some very remarkable
properties which quite eclipse the phenomena produced by the
spark of an ordinary Ruhmkorff coil.
If the current generated in the secondary of a Ruhmkorff coil be
passed through the primary of a Tesla coil, sparks will be obtained
from the secondary of the latter which differ from those of the
ordinary induction coil in that they have a very much sharper
sound, and are much more brilliant, and a long spark may be
Fig. 1.
taken through the body without any inconvenience arising. Tesla’s
original experiments are described in detail in the Journal of the
Institute of Electrical Engineers, vol. xxi., No. 97, and are highly
entertaining and instructive.
The following instructions will enable anyone to make a Tesla
which will give excellent results in radiography for a small, say
2 inch, Ruhmkorff.
The coil has no iron core, no contact breaker, a very simple and
easily made condenser, and very little solid insulation, and there¬
fore presents no difficulties to anyone in the making. The primary
is composed of one layer of No. 24 B. W. G. gutta-percha covered
Fig. 2.
copper wire in about thirty turns, which should be well separated
one from the other and wound on a glass or ebonite rod of one inch
diameter; the ends of the wire should be carried off through
rubber tubes so as to prevent any chance of contact with the
secondary.
The secondary is composed of about 400 turns of No. 36 double
silk-covered copper wire, which has been well soaked in melted
paraffin wax, or even better than this is a mixture of paraffin wax,
stearine, and resin. It should be wound on an ebonite tube of not
less than 1| inch internal measurement, so that there may be a
small space between the individual turns of the wire, and it should
be in one layer, and the ends of the wire taken out through glass
tubes.
The primary coil is supported on ebonite blocks, so that it
64
PHARMACEUTICAL JOURNAL,
[Jan. 23, 1897
passes through the secondary tube and leaves about J inch between
the primary and secondary, and the ends of the primary should
extend slightly beyond the ends of the secondary, as shown in
Pig. 1, as this increases the efficiency of the coil.
The whole coil is now placed in a glass dish, or as a substitute
smay be used a wooden box which has been rendered liquid tight
by means of shellac or asphalt. The size of the box should be
6^ x 4 x 2\ inches, and when the coil has been placed in position
it should be covered completely with boiled linseed oil, care being
taken that there are no air bubbles between primary and second¬
ary, and plenty of time should be allowed for the oil to soak well
in before the coil is used, as the oil is the insulating medium. The
connections of the coil are shown in Fig. 2.
The secondary terminals of the Ruhmkorff A are connected to
the primary of the Tesla coil B, of which C is the secondary. In
one wire there is interposed a “spark gap” E, which is
composed of two small brass balls very highly polished, one of
which is fixed and the other moveable, so that the distance
between them can be varied. The construction of this spark gap
is shown in Fig. 3, where A is the fixed ball and B the moveable,
being clamped by a small screw C.
Returning to the connections. Across the terminals of the
Ruhmkorff coil there is
placed a Leyden jar of about
one quart capacity, one coat¬
ing being attached to each
terminal as inD (Fig. 2). For
such a coil as above
described, the Ruhmkorff
Big. 3. may be designed to give any¬
thing from a 1J inch to 4-inch spark ; above this the Tesla must
be made larger.
Possibly a little more attention has been given to the construc¬
tion of a Tesla than seems at first sight warranted, but when it
is pointed out that with a Tesla made precisely on the above lines
we may use a Ruhmkorff coil giving only a | or 1-inch spark, and
yet obtain equally good results in radiography as using an 8 or 10'
inch Ruhmkorff direct, the extra description will be forgiven.
Action of the Tesla Coil.
The precise action which takes place is as follows : — The current
from the Ruhmkorff charges up the Leyden jar till it is able to
force a spark across the spark gap, the balls of which should be
about js inch apart, when of course the jar is at once discharged
through the primary of the Tesla, which induces a current in the
secondary, which, if the terminals are brought close together,
will make itself manifest as a spark. The whole apparatus, with
the exception of the Ruhmkorff, may be fastened down to a
wooden base so as not to allow of any displacement.
As has already been stated, the discharge may be used for X-ray
work, and the method of connecting up is shown in Fig. 2.
With a Tesla coil it is possible to excite considerable wonder in
an audience, for if a Crookes’ tube be connected to one terminal
only, and the other be held in the operator’s hand, and he presents
his other hand to the tube, it will instantly light up, and it is thus
possible for two people to take hold of one terminal apiece and
excite a Geissler tube by holding it in their disengaged hands, and,
again, if a Crookes’ tube be working and a Geissler, or even an
ordinary vacuum or Plucker’s tube be presented to it, the Geissler
will glow faintly, although the operator may not in any way be
connected with the coil. He then serves as an “earth,” or as a
conductor or escape of the current to earth.
The Ruhmkorff coil may be run by means of a bichromate battery
or an accumulator, but if the electric current be supplied to the house
by far the most convenient method is to utilise this, and for this pur¬
pose a wall plug will be required such as is utilised for table lamps.
If this is not available one should be fitted by an electrician, the
usual flexible wire as used for lamps will not generally be large
enough for the current required for anything like a good sized coil,
as it will only carry about 2 amperes with safety, and therefore
wires large enough to carry 10 amperes should be fitted.
Owing to the small resistance of the primary of the coil the
pressure of the mains will force too large a current through, and
therefore this must be modified by a resistance, which may be of
wire of the usual form that can be obtained from any electrician,
or what is more convenient, it may be a liquid resistance. This is
composed of two plates of stout zinc about 4 inches in diameter,
and j inch thick, to each of which a wire is attached, the wire
being enclosed in an indiarubber tube to prevent electrolysis ; the
zincs aresuspended some distance apart in a saturated solution of
zinc sulphate, the resistance being altered by moving the plates to or
from one another. A convenient way to do this is to place one
plate at the bottom of a tall glass or earthenware jar which has an
Fig. 4.
opening at one side, which is sometimes known as a settling jar,
the wire being brought out through this ; the other plate is
suspended from the top in such a way that the distance between
them can be altered, and the resistance increased or diminished at
will. The necessary connections are shown in Fig. 4.
The Use of Alternating Currents.
The above- described apparatus is suitable for continuous
currents, but as in some towns the alternating current is supplied,
the coil requires modifying as the to and fro alternation of the
current serves the same purpose as the contact breaker, which,
therefore, has to be cut out of the circuit, and the condenser is
alsouseless. In some modern large coils terminals are placed specially
for alternating currents, but with those that are not thus fitted
the contact breaker must be screwed tight up against the hammer
and a bit of copper wire wound tightly round the two. The con¬
nections shown above will then be suitable.
The ammeter in the diagram serves the purpose of giving in¬
formation of the quantity of the current passing through the
primary, and by which the current can be kept constant by altering
the adjustable resistance. The ammeter is of great importance
in radiography, as it really gives one some guide as to the
efficiency of the tube and the length of exposure. The ammeter
will have to be obtained for either continuous or alternating
currents, as the one will not do for the other, although there are
a few on the market intended for both.
The alternating current is not generally so suitable for coil
running as the continuous, as the frequency of alternation, which
is about 100 per second, is not so great as given by the contact
breaker to a continuous current, and therefore the sparks suffer in
consequence/ A Tesla coil cannot be run with any degree of
efficiency off the alternating current, owing to the low frequency
of alternation.
Jan. 23, 1897J
PHARMACEUTICAL JOURNAL
65
THE USE OF GAS FOR DOMESTIC LIGHTING.*
BY PROFESSOR VIVIAN LEWES.
It is not always possible to use coal gas as the source of illumina¬
tion on account of the capital charge represented in the generating
plant and the mains for distribution to consumers. Thus arises a
raison d'etre, for the employment of oil gas and other illuminants.
Oil gas, as its name implies, is the inflammable vapour given off by
certain liquid hydrocarbons. There are a large number of carbon
and hydrogen compounds, ranging from solids, such as paraffin
wax, down to the oils used in the domestic lamp. The higher
compounds may usually be reduced by heat, converted into the
gaseous form, and made suitable for employment as an illuminant.
The gas at present most largely used is that obtained from the
“ leavings” after the distillation of Russian petroleum.
A gallon of Scotch oil may be converted by Young’s process of
reduction into 98 cubic feet of gas. (This process, which was
briefly explained, effects the reduction at a somewhat lower tem¬
perature than former processes, and therefore retains certain
volatile products, such as benzenes, compounds, etc., which add
to the illuminating power of the gas. ) The following table com¬
pares analyses of gas made respectively by Young and Patterson —
two typical processes.
Paterson. Young.
Unsaturated Hydrocarbons . 33 '16 43 '83
Saturated ,, . _.. 45-45 36-30
Hydrogen . 19-35 16‘85
Carbon Dioxide . -50 "63
Carbon Monoxide . -50 —
Oxygen . -60 1-14
Nitrogen . -44 l-25
100-00 100-00
The illuminating power, in candles =* 50 60
Passing to the newest illuminant, acetylene was first spoken
of as a commercial possibility four years ago. It was known as far
back as 1838, when it was found, with ethane, by E. Davy — a
relative of the great Sir Humphry. Berthelot, the great French
chemist, took up the investigation of this hydrocarbon in
1850, but did not suggest a method for easily preparing it, though
he added much to the knowledge of the properties of the gas. The
only known method was to take advantage of the fact that acetylene
gas was produced during the incomplete combustion going on in the
interior of a luminous flame, but the process of obtaining it was
long, laborious, costly, and not over safe.
In 1890, T. L. Willson, of N. Carolina, experimenting with his
electric furnace with calcic compounds in the hope of reducing
them by high temperature, and obtaining calcium in that way,
was time after time disgusted to find the only result he got was a
fused metallic mass not particularly nice smelling, and certainly not
exhibiting any resemblance to calcium. He threw it away with every
gesture of disappointment into a stream which ran close by, when,
to his intense surprise, a brilliant, illuminating flame leapt up
immediately on the contact of the fused substance with the water.
Willson repeated his experiments with coke and lime under properly
observed conditions, and finally hit upon the secret of calcic
carbide, and solved the question of the commercial production of
acetylene gas. The compound discovered by Willson, and to which
the name of calcic carbide has been given, is composed of carbon
and calcium, in the proportion of two of the former to one of the
latter. As it is the product of the highest known temperature, it
naturally defies high temperatures, and cannot be dissociated by
concussion. It will stand fire and shock, but like a street arab it
* Notes of lectures delivered at the Society of Arts. See last volume,
pp. 490, 532.
cannot stand water. (Lecturer demonstrated each of his
points by experiment. ) This not over-elegant portion of carbide
contains the latent power of generating on the addition of water
the most powerful illuminating gas known. A double decompo¬
sition takes place ; the calcium of the carbide taking hold of
the oxygen of the water, and the carbon combining with the
hydrogen to form acetylene. Acetylene, therefore, is a gas com¬
posed of 24 parts, by weight, of carbon, and 2 parts, by weight, of
hydrogen. This substance (carbide) has been before us a few
years, but its price has, until very recently, been rather prohibi¬
tive. At present it is anything from 6s. per cwt. to several pounds
per ton, but several circumstances combine to keep the price up.
The Acetylene Gas Company, which has recently erected a special
factory at Foyers for the production of calcic carbide under
Wilson’s patents, recently lent me (the lecturer) certain plant with
which to experimentally ascertain the cost of producing car¬
bide. It was found that one electric horse-power gave 3 to *4
pound of the compound. Now the cost of the electric h.p.
varies in different parts, and will be least in those places
where water-power is available. The Acetylene Gas Com¬
pany have ample water-power, and can hence produce
at a cheaper rate. To a large extent the manufacture is
a monopoly protected by patents, and, for a time at least, acety¬
lene cannot rival coal gas. British carbide is the best in the
market, and contains over 90 per cent, of CaC2, and evolves 5 cubic
feet of acetylene per lb. French and Swiss makes rarely give
more than 4 cubic feet and the German only 3 '5 cubic feet. Pure
carbide is perfectly safe if kept dry, but when impure it is some¬
times very dangerous. SH2 is commonly present to the extent of
2 per cent. , but it does not constitute a danger, though its presence
is unpleasant to the nose. Much more dangerous impurities
are the phosphides of calcium, which, when decomposed, give
rise to phosphoretted hydrogen and bring about spontaneous
combustion (combustibility of foreign carbide shown). No
doubt the charcoal from which the carbide was made con¬
tained traces of phosphorus, or perhaps phosphates were
present in the lime. Now, the danger here is this ; in the col¬
lection of acetylene in the gasholder there must come a moment
when that holder contains an explosive mixture of C^H,} and-
air. If at that moment phosphoretted hydrogen is present, all the
elements of disaster are there, and an explosion occurs. Another-
dangerous impurity is ammonia. In the presence of ammonia and
moisture acetylene attacks copper and copper alloys, producing
explosive compounds. There is no danger if care is taken to use
pure materials in making the carbide. A good deal has been
made of the dangerous nature of carbide and acetylene, but only
by those ignorant of the properties of the substances. If, as was
actually the case, eight tons of carbide are sent by rail in open
trucks one must not be surprised at something happening if a
shower of rain fall, but if properly stored the danger is no greater
than that experienced in the storage of benzene or coal gas.
Most of the accidents have been the result of careless handling
by ignorant persons, or the reckless experiments of up-to-date
amateurs. With regard to generators, most of the acetylene
generators at present on the market are unsafe. The point to be
aimed at is to have a small portion of the carbide acted upon, and
to be able to stop the evolution at a moment’s notice. In the
generation an amount of heat is evolved as the outcome of the
double decomposition which is sufficient to decompose the acety¬
lene. This gives rise to “choking” of the pipes and formation of
explosive hydrocarbons, hence the necessity for not having an
excess of carbide. Again, in some generators the water is merely
drawn off the carbide, but the latter is left damp and still evolving
6G
pharmaceutical journal.
[Jxx. 23, 1897
gas, with the result that a self -compression goes on in the contents
of the gasholder, which may give rise to serious conditions.
(Several apparatus for generating gas were on exhibition, and
special praise was accorded to one on the diving-bell principle. )
With reference to burners it is advisable not to have the orifices
too fine or choking results. The ordinary flat flame burner is as
good as any, and a flame consuming 1 cubic foot of gas per hour
will emit a light of from 32 to 34 “candles.” The life of such a
burner is about 400 hours. ( All sorts of burners were shown in action,
to the great optical suffering of those in the front row of the
lecture room.) With a greater consumption of gas a better power is
obtained, and with a consumption of 5 cubic feet per hour a power
of 240 candles may be obtained. The illuminating power of other
hydrocarbons may be gathered from the following table
Methane . 5' candles.
Ethane . 35 ‘7 ,,
Propane . , ... . . . 56’7 ,,
Ethylene . - . 70‘ ,,
Butylene.. . 123‘ ,,
In each case a consumption of 5 cubic feet per hour is assumed.
A great future is before the acetylene light in the illumination of
the interior of railway carriages and tram-cars, but the dangers
attending compression of the gas have yet to be overcome.
GELATIN CAPSULES.*
BY WM. C AI.PEBS
( Concluded from page 27. )
2. Filling the Capsule with Powders or Pill Mass.
There exists a great diversity of opinions as to the proper way of
dispensing medicinal media in gelatin capsules. While some phar¬
macists claim that a mass should always be prepared, others contend
that the only proper way is to fill the mixture of the various items
of the prescription in powder form into the capsule. Under certain
circumstances both may be right. Physicians are not always
explicit in writing prescriptions, and often omit to state in what
form they wish the medicine administered. If they would simply
add “ fiat massa in capsulas dividenda,” or “ fiant pulveres in cap-
sulas dividendi,” all doubts would be dispelled. But there are only
a few who do this, and as long as the modus operandi is left to the
judgment of the pharmacist a definite rule should be adopted.
The public in general prefer capsules filled with powder, and all
pharmacists know the sometimes very troublesome customer who
will insist on having his 20 grains of quinine put into ten capsules,
because “ they act better that way.” The argument that a dry
powder is more readily dissolved or absorbed than a more or less
compressed pill, is a very plausible one and hard to refute. In
reviewing prescriptions on which capsules are ordered, we will find
that the majority, almost 65 per cent., are orders for pills, that is to
say, they contain ingredients whose mixture will result in a pill
mass. Vegetable extracts of more or less soft consistency, oils of
various natures, articles like oxgall or ichthyol, and similar drugs,
:all these can only be prepared in pill form ; for to make powders
of them would require an addition of so much absorbing powder
as to make the powders unreasonably large. To this class we
must also count those prescriptions that contain deliquescent
salts or such chemicals which by their mixture will turn
moist or liquid. There can be no question about such prescriptions
and our investigation is therefore restricted to prescriptions that are
composed only of dry ingredients, or in which the amount of liquid
medicaments, like a few drops of some ethereal oil, is so small that
it will be readily taken up by the solid ingredients without the
addition of any absorbing powder. What is ordered in such cases,
powders or pills ?
# Read before the American Pharmaceutical Association , at Montreal
Let us take analogous cases. Would a pharmacist think of
changing a prescription for pills into one for powders, or one for
powders into a liquid ? Is it not the rule to dispense conscien¬
tiously whatever is ordered, and not alter a prescription in the
least, unless the limits of safety have been transgressed? Why
then should a mixture of drugs ordered in powder form be changed
into a pill mass ? A capsule is, according to all authorities, a cover
for nauseating or strong- smelling medicines, no teacher or encyclo¬
pedist restricts its meaning to pills alone. A pharmacist, therefore,
has no right to suppose that a physician wishes to order a pill mass
when he orders powders, especially as the prescriber has it in his
power to add the words “fiat massa,” and thereby express such desire
if it existed. Where, however, such a remark is wanting, there is no
reason why a mass should be formed. Powders , not pills are
ordered to be put into capsules, and the pharmacist who changes
the powders into a mass doubtlessly transgresses the limits of his
professional liberties. And what other motive to do so can there
exist, but the desire to save time and labour ? The tendency of
late years to prepare prescriptions at lower prices than all the com¬
petitors and sacrifice everything to cheapness, has reduced not only
the time allotted to each prescription, but also the care and solici¬
tude so necessary in the fulfilment of our professional duties. It
goes quicker to make a mass and cut it into so many parts than to
carefully weigh each powder, and let the accuracy with which the
last powder balances the calculated weight serve as a proof of the
correctness of all powders.
It is claimed that in many instances the bulk of the dry powder
would necessitate a very large capsule, while a mass could be com¬
pressed to a much smaller volume. In answer to this argument we
must not forget that it is not the pharmacist’s province to regulate
the bulk of the medicine, or to correct a physician, as long as the
dose is within the limits of safety. If a physician chooses to order
a mixture containing as a dose one -sixtieth grain of strychnine dis.
solved in a tablespoonful of some aromatic liquid, no pharmacist
would consider it his duty to change the tablespoon to a teaspoon,
and thereby reduce the bulk of this medicine to one-fourth of the
prescription under the plea that the bulk of the dose was too
large. If, therefore, the physician orders a powder to be put
into capsules and the largest capsules alone will hold the pre¬
scribed dose, there is no reason why the pharmacist should
change the order. Nor is it always true that a mass will reduce
the bulk. In the first place it is always necessary to add some ex¬
cipient, if it be only water, thereby adding to the weight ; very often
adhesive vehicles as gum acacia, tragacanth, various mucilages or
glycerites are needed to form the mass. The danger of adding a
little too much of a liquid vehicle, and then being c impelled to
correct the mistake by adding some solid, often increases consider¬
ably the bulk of the mass without adding to its medicinal properties.
Furthermore, while all these ingredients may be perfectly harmless,
if considered by themselves, they may yet change the finely-
comminuted powder to a hard lump, which instead of being easily
assimilated by the patient would pass undissolved through the
system, or even be the cause of serious digestive disorders. Lastly,
we may also state that although there are people who prefer small
capsules to large ones, there are just as many who will take a large
capsule as readily as a small one.
A few words may be added about the filling of capsules, which
seems to be a difficult task to some pharmacists. Whenever a mass is
first prepared, little difficulty is experienced. The general pro¬
cedure is to roll the mass and cut it into the required number of
pieces, in such a way that each piece has the shape of a small
cylinder, of a diameter a little smaller than that of the body of the
selected capsule. The operator should then wash his hands, in
PHARMACEUTICAL JOURNAL.
67
Jan. 23, 1897.]
order to remove all traces of the mass, and then introduce the small
cylinders into the capsules by means of a needle with which he picks
them up. As especially fit for this work, I mention the small bota¬
nical needles used in dissecting flowers, which are provided with
a wooden handle, an instrument that every pharmacist can prepare
himself. The covers are afterwards put on with the fingers. By
this method the odour as well as the taste of the ingredients of the
mass are thoroughly covered by the capsule. Care should be taken
not to select too large a capsule, so that the mass after drying will
fill only half the space ; but even with the greatest care in preparing
the mass a shrinking will afterwards take place, an inconvenience
which it seems impossible to overcome.
During the last year I have given this method of filling capsules
my special attention, and compared repeatedly the cylindrical parts
of the mass by weighing them. In very rare instances have I found
two parts that weighed exactly the same, the variation in my own
work ranging from a fraction of 1 per cent, to 3 per cent., in spite
of the greatest care exercised. Experiments with masses cut by
other operators showed a similar, sometimes worse, result. I have
discovered two apparently equal pieces of the same mass to vary as
much as 8 per cent. In most instances this lack of exactness seems
to be irrelevant, but we must admit that if we once allow a varia¬
tion it is hard to draw a limit. I have therefore adopted a better
and more correct method, and during the last six months instructed
my assistants to weigh the mass, divide the weight by the number
of capsules ordered, and then weigh each part separately before
putting it into the capsule. Objection might be raised that this is
a troublesome and tedious procedure. But this is not so. By using
the metric weight a division is quickly made, and the weighing of
from 12 to 20 small parts requires no longer time than the rolling
and cutting.
To introduce powders into the capsules is not quite so simple, and
requires a small apparatus to insure correct results. Some pharma¬
cists resort to the rather crude method to put the powder, without
dividing it, on a piece of paper, take the body of the empty capsule
between the fiDgers in the left hand and the cover in the right, and
fill both by shoving them through the powder repeatedly. This
method, which is even recommended in one of the newer works of
pharmacy as the best means of filling capsules, is objectionable in
more than one respect. In the first place it is impossible to gauge
the quantity of the powder that is thus introduced into the capsule,
and repeated weighing of each capsule becomes necessary, until
the correct weight is reached, sometimes after many trials.
Secondly, the very object of the capsule is entirely ignored ; par¬
ticles of the mass will adhere to the outside, and neither taste nor
odour of nauseating medicines can afterwards be entirely removed.
A capsule filled with quinine in this manner will taste bitter
no matter how often it is wiped after filling, and if the mass
should contain such strong smelling ingredients as asafcetida
or valerian, their odour can never be removed. The proper
way, insuring correctness and elegance, is to weigh each
powder separately, and introduce it into the empty cap¬
sule by means of a small apparatus, of which various kinds
are in the market. There is Reymond’s capsule filler, con¬
sisting of a block of wood with a number of sockets for the
empty capsule, and a second block with a corresponding number of
funnel-shaped receptacles. Another instrument, the Davenport
capsule filler, consists of a metal funnel for the capsule and a
plunger. Both these and other apparatus have their advantages
and drawbacks.
I have here an instrument which I think is an improvement on
the others. It consists of a base (Fig. 2), with a number of small
plugs, and a block (Fig. 1), with a corresponding number of holes
into which the plugs fit ; these holes are widened at the upper side
into small funnels. At the sides are pegs as guides for the upper
block, so that each hole will be exactly over each plug. In the
centre of the baseboard there is a small metal rod with a thread
for a screw-nut at the upper end ; the nut for this thread is held on
the upper side of the perforated block by an overlapping flange, and
can be turned easily by means of a pair of wings. A short plunger
(Fig. 3), concave at one end and convex at the other, completes the
apparatus. The modus operandi explains itself. The two blocks are
arranged so as to place the upper one over the lower one, the
empty capsules are introduced and pushed by means of the
plunger into the perforation until they touch the plugs ; if neces¬
sary the upper block is lowered by means of the screw until the
upper parts of the capsules are even with the funnel-shaped widen¬
ing of the perforations ; the powders, each one having been weighed,
are put into the funnels and pressed down with the concave end of
the plunger, leaving a small elevation over each capsule for the
hollow of the cover. By a few turns of the nut the capsules are
now partially raised out of their casings, high enough to put the
covers on, these latter might be moistened inside with a trace of
water by means of a camel’s-hair pencil, and thereby glued on.
After the covers are put on, a few additional turns of the screw will
raise the capsules entirely out of the casings.
As a rfoumi I would submit the following rules : —
1. Always follow the physician’s directions as to the formation of
a mass.
2. If no directions are given, form a pill mass whenever the
ingredients cannot be mixed in powder form. Weigh the mass,
divide the weight by the number of capsules ordered, weigh each
part and give it the shape of a small cylinder by rolling it between
the thumb and first finger. Wash the fingers and introduce the
cylinders into the capsules by means of a needle.
3. If no directions are given, and the ingredients of the prescrip¬
tion will form a powder, divide their combined weight by the number
of capsules ordered, weigh each powder separately and introduce it
in powder form into the capsule by means of a convenient apparatus
Under no condition should the undivided powder be forced into the
capsules by moving the bodies and covers through the powder from
opposite directions.
68
PHARMACEUTICAL JOURNAL.
[Jan. 23, 1897
METRIC MEASURES AND OUR OLD SYSTEM.*
BY FREDERICK TOMS.
Sooner or later the British public will have to accommodate it¬
self to another system of weights and measures. A Bill to
legalise the decimal-metric system has been brought into the
House of Commons, and will probably receive parliamentary sanc¬
tion ; but its adoption appears to be merely permissory. The
advocates of the new system, however, are not likely to be content
with this, as many are of opinion that the use of metric measures
should be made compulsory, as has already been done in many
other countries. But before taking this extreme course, with all
the inconveniences which such a change must necessarily entail
upon immense numbers of people — and more especially upon the
least educated portion of the community, who are not receptive of
new ideas — it may be desirable to regard, not merely the merits of
the new system, but all its defects. Likewise let us take into con.
sideration the good points of our old system (with which every¬
body — man, woman, and child — is familiar), and then endeavour to
ascertain whether it may not be possible to combine the best
features of the two ; so that the advantages of the metric method
may be added to the facilities of our present practice, and the new
system be brought into operation with the smallest amount of
disturbance to the business proceedings and domestic habits of
the British nation as a whole.
For simplicity in scientific calculations, and for large commercial
transactions, the metric method cannot be surpassed ; but the
decimal arrangement does not really adapt itself to the minor tran¬
sactions of retail trade and ordinary dealings of the poorer classes,
whose purchases require greater facility of subdivision. It is re.
corded that, long before the present metric system was devised, Charles
XII. of Sweden proposed the number 12 for the arithmetical base,
and said : “ It is quite ridiculous to use 10 as the base for arithmetic,
it can only be once divided by 2, and then stops.”
It would be absurd, however, to attempt now to establish a
duodecimal base for arithmetic. But having a duodecimal method
of weights and measures already in operation, and familiar to
everybody, it would be almost as ridiculous to throw away its many
advantages in order to make the habits and customs of the com¬
monality, as regards their purchases and sales, subordinate to the
restrictions of a code of decimals. By all means adopt the base of
the metric system — in order to place yourself on a similar footing
to most other civilised nations — but do not discard your old
facilities of subdivision. You may, on the contrary, if so disposed,
increase those facilities by adding to the halves, quarters, thirds1
sixths, eighths, twelfths, and so on, which are found in our presen -
code, the fifths and tenths which occur in the decimal code ; and thus
people would gradually become familiarised with the metric
system in general.
The want of the old subdivisions has been a source of vast trouble
and inconvenience to the French people ; and they have tried to
palliate the inconveniences by applying old names to new divisions.
But when proportions are also altered, this is merely grasping at
the shadow while losing the substance. Let us retain the old pro.
portions together with the old names, while slightly varying the
basis whereon they are founded. We shall thus be brought into
touch with all nations which have adopted the metric system, and
our measures will be readily convertible into theirs ; while we shall
still keep our existing methods, and not deprive the mass of
the people of the familiar knowledge which they already
possess.
* Paper read at the meeting of the British Association for the Advance¬
ment of Science, held at Liverpool in September, 1896.
It seems a pity that when, in the year 1790, a proposition having
been sent by the French Government asking for the appointment of
an international conference (combining an equal number of
members of the Academie Franchise and of the Rojal Society of
London) — for the purpose of taking steps to devise a new system
of measures — nothing was done on our side of the Channel towards
carrying the suggestion into effect. But it is not surprising that,
amid the political complications of that troublous period, the
British Government did not see its way to give such proposal a
favourable reception. France, however, not being successful in
obtaining the co-operation of England, appointed a commission of
its own, which included some of the most celebrated scientific men
of the time. Among them was one practical mathematician and
astronomer who had shortly before taken an active part in bringing
the observatories of Paris and Greenwich into closer relations ; and
another was a French member of our English Royal Society. So
here, it may be supposed, were at least two commissioners who
would have been able and willing to work in unison with English
confreres. And if such men as these could have been associated
with equally competent men of our own nation, it is not impossible
that a means might have been discovered for placing the new
French system on practically the same basis as the old English
method ; for, as Sir John Herschel afterwards pointed out, the
English inch was more exact than the metre as a unit whereon to
base the whole metric system.
But, although it is useless to cry over spilt milk, one cannot dis¬
regard the fact that the task to be accomplished is much more
difficult now than it might have been a century ago. Then, a
difference in length of the metre by a few thousandth parts, more
or less, would have been a matter of comparatively small import¬
ance. The main principle could have been worked on exactly the
same lines ; and all the advantages of this admirable system might
have been conferred upon the world in just the same degree as
exists at present. But there would have been the additional and
immense advantage that, if the metre had been altered by a small
fraction, so as to make it accord with eleven-tenths of the English
yard — or if the yard had been varied in some slight degree, so as to
make it correspond with the metre — the two systems might have
been put into simultaneous operation in both countries, and serious
arithmetical and business difficulties, extending over a hundred
years, would thus have been spared to the world.
The slight alteration which might then have been effected, by a
little judicious negotiation between two friendly nations, is no
longer possible, as about thirty diff irent countries, large or small,
have now adopted the metric system in some degi ee — though not
always in its entirety ; and many of them have transferred their old
names to the new weights and measures. It is obvious, therefore,
that whenever the ultimate change comes — as come it must — some
alteration will have to be made in the British unit of length. How,
then, can this change be effected with the least amount of disturb¬
ance in our existing arrangements ?
The metric system has already been adopted by scientific men ;
and, for their purposes, its original form is much preferable to any
modification. Where help is really required, in effecting the
change, is solely among those people who have no knowledge of
decimal weights and measures, but who are thoroughly familiar
with our English system. Before they can utilise the metric method
they will have to undergo a process of education. What is requi¬
site, therefore, is that our grown-up population — which cannot be
sent to school again — should not be arbitrarily and suddenly
deprived of the system which they know, but they should gradually
be made acquainted with the new process by utilising the informa¬
tion which is already at their command. In this way the change
Jan. 23, 1897]
PHARMACEUTICAL JOURNAL.
69
from one to the other may be effected ; but it must be a work of
time. Compulsion is not needed ; but guidance is.
The key to the conversion process — which is suggested by the
fact that the metre is just about one-tenth longer than our present
yard — is simply to divide the metre into eleven equal parts, and
take ten of these parts to represent the new English yard.
This proposed new yard could be subdivided and used in exactly
the same manner as the old measure ; and the difference between
the inches, feet, and yards would be scarcely perceptible to ordinary
observers, as they would be only a small fraction shorter — each
being barely -006 less than its present length.
The impression may possibly be formed that the use of the
number 11 would render calculations difficult, seeing that it is not
divisible. There is no necessity, however, to divide that number •
but it will be found very useful in converting English measures into
metric equivalents, as our existing codes of long and square
measures contain multiples of that number, and the use of 11 (or
its decimal 11) fits in wondrously well with the conversion of yards
into metres, and vice versa.
If, for example, the metre be taken as equivalent to el even- tenths
of a yard, a kilometre (or 1000 metres) would be equal to 1100
yards — i.e., exactly 5 furlongs. A hectometre (or 100 metres) would
be just the same in length as 110 yards, or half a furlong ; a deka-
metre (or 10 metres) would be equal to 11 yards — i.e., double the
length of the English rod, pole, or perch, which measures 5£ yards.
In short, take any number of metres, multiply them by 11, and you
get their equivalent in yards ; or take any number of yards, and
divide them by IT, and you obtain the corresponding number of
metres.
The 11-10 process would be quickly comprehended by mechanics
when they found the metre to be exactly one-tenth longer than the
yard. The peasant would soon put this and that together if he saw
the milestones inscribed with “8 kilometres— 5 miles,” “9 kilo¬
metres— 5 miles 5 furlongs,” and so on. Even the skilled
geographer need not be above admitting that the circumference of
the earth is the same whether it be represented as 25,000 miles or
40,000 kilometres, and by 44 million yards as well as 40 million
metres. He may aver that the French philosophers somewhat
under-estimated the earth’s circumference ; but it is a century too
late to rectify that slight difference ; and the evenness of the
numbers and facility of conversion are certainly a great aid to
memory.
With our apparently complicated method of land-measurement
the metric system would fit in remarkably well when 11 yards are
made exactly equivalent to 10 metres. Farm labourers, as well as
the farmers themselves, would perceive that the French system>
though unfamiliar at first, is more simple than ours ; and it will be
easy to convert the one into the other. Our English measures are
divisible by 11, from the acre of 4840 square yards downwards.
Even our square rod, pole, or perch (which is equal to the seemingly
odd number of 30J square yards) becomes simplified by the metric
system, as the length of the rod is 5^ or 5 5 yards, and the same
length would be exactly 5 metres ; while it goes without saying
that 5 times 5, or 25 square metres, is more simple than 5| times
5J, or 30J square yards. This square perch, too, would be exactly
one-fourth the size of the French are ; and 10 ares would be the
same as our rood ; 100 ares form the hectare, equal to 10 roods, or
2^ acres ; while our square furlong, containing 10 acres, would be
exactly 200 metres square. Our square mile, too, which contains
640 acres, would be equal to a square the sides of which measure
1600 metres ; and, as 16 times 16 amount to 256, there would be
256 hectares as the equivalent of our square mile of 640 acres.
(To he contmued.)
PARLIAMENTARY NOTES AND NEWS-
The Third Session of the present Parliament opened on the
19th instant — a date considerably in advance of that usually asso¬
ciated with the inauguration of a new session. It is not likely,
however, that the extra fortnight or so will be found superfluous,
for in addition to the by no means trivial labours indicated in Her
Majesty’s Speech, there are grievances “in the air,” and it does
not require much foresight to enable one to announce the proba¬
bility of talk on the alleged over-taxation of Ireland.
Education is apparently to take first place in the ministerial
programme, and this is only in accord with the repeated pledges
given by responsible ministers last session. Then follows the
question of compensation to workpeople who suffer from accidents
in the course of their employment ; and the London water supply
will also receive legislative attention. These items, together with
the Military Defences of the Empire, and the promotion of agri¬
culture in Ireland by the establishment of an Irish Board of Agri¬
culture, are prominent in the Westminster programme for 1897.
Chemists will, however, have more interest in the announce¬
ment “ in Her Majesty’s own words ” that during the session a
Bill will be introduced for the revision of the Acts relating to the
formation and administration of limited companies. Since this
item last figured in the Queen’s Speech the abuses — and there is
no milder term for it — of the privilege of incorporation have been
more pronounced, and the revision of the law has now become an
urgent public necessity. The Bill to be introduced will doubtless
be that which was referred to a Committee of the House of Lords
last Session, and on its reappearance it is probable the Committee
will be re-constituted, and will at once proceed with its work.
Those who are credited with knowing — in a parliamentary sense — -
“a thing or two,” are not, however, sanguine that the current
Session will witness the enactment of a measure on the subject.
The Hon. Alfred Lyttelton, who seconded the Address, is
the popular member for Leamington and one of the few
members of the House who maintain a sympathetic attitude
towards the legislative aspirations of chemists and druggists. It
is due to the commendable activity of the chemists in his con¬
stituency that Mr. Lyttelton knows so much about pharmacy and
the Pharmaceutical Society, and that he may be counted on to
understand and carefully consider anything pharmacists may
have to say through their accredited representatives.
Mr. Kearley (Devonport) is evidently determined to be no less
active this Session than he was last. He did a lot of Committee
work in 1896, notably in connection with the Select Committee on
Food Products, and he is disappointed that no reference in the
Queen’s Speech has been made to probable legislation on the
subject. He will therefore move an amendment to the Address
expressive of regret at what he considers so glaring an omission.
Royal Commissions and their cost form the subject matter of a
very instructive Return just issued from the Home Office. It
appears that the Vaccination Inquiry cost £13,040, and lasted seven
years ; the first Commission on Tuberculosis took £6156 out of the
Treasury ; the Gresham (university scheme) Commission £2823 ;
the Opium Inquiry £18,503 ; Secondary Education £5329, whilst the
Chicago Exhibition Commission, which comprises the President,
Vice-President and Council of the Society of Arts, managed to run
up a bill of £61,464. Whether the country has had the money’s
worth is a question that may safely be left with Mr. J. Ellis, on
whose motion the Return was ordered.
70
PHARMACEUTICAL JOURNAL.
[Jan. 23, 1897.
THE STUDEHTS’ PAGE.
MEASURES USED IN PRESCRIPTIONS.
For special use in compounding prescriptions the following
denominations of measures of capacity were legalised in 1879 : —
The fluid ounce (the measure of 437 ‘5 grains, or ounce avoirdupois,
weight of water), the fluid drachm (the eighth part of the fluid
ounce, and the measure therefore of 54 68 grains of water), and the
minim (the sixtieth part of the fluid drachm and the measure of
•91 grain of water). This want of a simple relation between the
subdivisions of the ounce and the fluid ounce are a fruitful
source of error to the student. He should be very careful to
bear in mind that the only weights employed in the body
of the Pharmacopoeia are the grain, the ounce (of 437 '5 grains),
and the pound (of 7000 grains). The necessity for this will be
more evident when he attempts to calculate the amounts of sub¬
stances to be taken for preparing smaller quantities than those
ordered in the official processes. Supposing, for example, he
wishes to make one-eighth of the official quantity of liq. amm. acet.
fort., in which 15£ ozs. of carbonate of ammonia are neutralised
with (about) 50 fluid ounces of acetic acid. Being familiar with
the fluid drachm as the eighth part of a fluid ounce, he will take
151 drachms as the eighth part of 15^ ounces, and 50 fluid drachms
as the eighth part of 50 fluid ounces, forgetting that the drachm
(60 grains) is not the eighth part of the ounce (437 -5 grains).
Another point upon which the student is likely to err is in the
making of “percentage” solutions, that is solutions which shall
contain a certain percentage of some specified body. For instance,
a 1 per cent, solution of corrosive sublimate in water, spirit or
ether may be required. Now a 1 one per cent, solution is a
solution that contains in one hundred parts by weight one part by
weight of the desired constituent, and such percentage solutions
as those alluded to should invariably be made by weighing one
part of the active constituent and adding solvent until the product
weighs 100 parts. Taking, say 10 grains of corrosive sublimate
and dissolving it in water, spirit, or ether sufficient to produce
1000 grains of solution, the volumes produced will differ consider¬
ably, Dut in each case a “ 1 per cent. ” solution will be produced,
since 100 parts by weight will contain 1 part by weight of corrosive
sublimate.
But if a solution is ordered “ 1 in 100,” then the case is different.
Some pharmacists understand this to mean 1 grain in 100 minims,
whilst others consider 1 grain in 100 fluid grains to be the correct
rendering, the fluid grain (or grain measure) being the measure of a
grain weight of water (and therefore not identical with the
minim). Probably the former more usually represents the pre-
scriber’s desire, since he is certain to be well acquainted with
the relation of the grain and minim, but may not be so familiar
with grains and fluid grains. Here the student must remember
that the fluid ounce contains 437 -5 fluid grains, and that such
solutions can be made only by weighing the substance and, after
solution, bringing the product up to a definite volume.
THE FLOWERS OF JANUARY.
Veronica buxbaumii. — This pretty little weed may be found in
cornfields, and is easily recognised by its axillary blue flower,
cordate, serrate leaves, and its compressed ovary with two spread¬
ing keeled lobes. The flower, like the rest of the genus, has only
two stamens developed, and the flower does not at a first glance
seem to be irregular. If carefully observed, however, it will be
seen that the lowest petal of the four is rather narrower than the
rest. The corolla is gamopetalous, wheel-shaped (rotate), and
very easily falls off. The ovary, if cut across, is seen to differ
from that of the Labiatse in being two-celled and containing
numerous seeds. Some of the Labiatse (e.g., rosemary) have also
only two stamens developed, so that the structure of the ovary is
very useful for distinguishing the two natural orders.
Ghimonanthus fragrans. — Amongst the garden flowers worth
examining by those who have the opportunity, is this Chinese
shrub, which flowers before the leaves appear. The flowers are
difficult to make out, since the membranous bracts run into yellow
sepals, and the sepals into yellow petals veined with red. The inner
stamens have no anthers, but the outer ones have anthers opening
outwardly (extrorse), and the carpels are distinct and line the
hollowed-out pedicel, as in the dog rose. But from the rose family
it differs in the opposite leaves, and the wood has the curious disc¬
bearing wood-cells, found in the Calycanthaceee (to which it belongs)
as well as in the Magnoliaceae.
Drimys winteri and Illicium religiosum (see Ph. ./. , Jan., 1877, p.
609) are usually in flower this month at Kew and other botanical
gardens. These plants will serve to show the leading features of
the cohort Ranales, to which, in common with the Ranunculacese,
these families belong, agreeing with the latter in the apocarpous
ovary and numerous hypogynous stamens. In the Magnoliacese,
however, the plants are mostly trees or shrubs, and the alternate
leaves are usually simple and entire, and the parts of the flowers
arranged in whorls of three. In the Calycanthaceae the leaves are
opposite and the carpels immersed.
Hamamelis arborea is another interesting shrub now in full
beauty at Kew in the open ground, which differs from H. virginica
chiefly in the red calyx, which contrasts well with the golden-yellow
ligulate, twisted petals. The parts of the flower are in fours, but
there are four abortive scale-like stamens between the fertile ones,
and opposite to the petals. The ovary is inferior, two-celled, with
one ovule in each. It belongs to the Hamamelidacese (Calyciflorge).
THE STUDY OF THE B.P.
Acidum Chromicum. — This is really chromic anhydride, Cr03 : it
forms chromic acid when dissolved in water.
Cr03 + H20 = HaCr04.
When the anhydride is heated, chromic oxide is formed with evolu¬
tion of oxygen—
2Cr03 = Cra03 + 30.
When a metal forms two or more oxides the higher oxides usually
have acidic properties, and the lower ones basic. This is well ex¬
emplified by the oxides of chromium ; Cra03 does not combine with
water to form an acid, but with acids to form salts, e.g., Cr2Cl#,
cf. oxides of manganese. Chromic acid is an energetic oxidising
agent. With hydrochloric acid —
2H2Cr04 + 12HC1 = CraCl8 + 8H20 + 3C12.
2HaCrO.
/ 2HvO
1 2CrO,
5 Cr203
3 * 30>3H20.
6HC1
6H'
6C1
The reduced chromic oxide forms chromium chloride with
more hydrochloric acid. The chromium salt gives the green solu¬
tion which is produced when chromic acid acts as an oxidising
agent in acid solution. The oxidation of cold alcohol gives rise
to aldehyde ; at higher temperatures acetic acid is also produced.
In all these actions two molecules of chromic anhydride yield three
atoms of oxygen —
2CrO„ = Cr203+30,
and two molecules of the anhydride will convert three molecules of
alcohol into aldehyde or three molecules of aldehyde into acetic
acid — •
C2H,OH + 0 = C2H40 + H20.
Aldehyde.
CaH40 + 0 = CaH40, (or HC2H3Oa).
Acetic Acid.
Acidum Hydrochloricum. — Note that the acid is to be “diluted
with four times its volume of distilled water,” before adding the
barium chloride solution for the detection of sulphuric acid. The
addition of BaCl2 solution to the strong acid would result in
precipitation of barium chloride, this salt being insoluble in
concentrated hydrochloric acid. The test with copper foil is to
detect arsenic, which might be present if impure sulphuric acid
had been employed in manufacture. The next test has been already
explained under “Acidum Aceticum.” Indigo solution would be
decolorised if chlorine were present, the latter acting as an
indirect oxidiser (H O + Cl2 = 2HC1 + O) and converting the blue
indigo into a colourless derivative.
Acidum Meconicum. — The red meconate of iron is decomposed
by strong, but not by weak hydrochloric acid. Compare this test with
those for acetates and thiocyanates. Both give red ferric salts on
the addition of ferric chloride in neutral solution, but the ferric
acetate is decomposed by both weak and strong hydrochloric acid,
the ferric thiocyanate by neither. Formation of precipitate with
iodine solution would indicate presence of morphine or other
alkaloid.
JAN. 23, 1897]
PHARMACEUTICAL JOURNAL.
71
PmumoEUTifflu. Jourmul.
A Weekly Record of Pharmacy and Allied Sciences.
ESTABLISHED 1841.
Circulating: In the United Kingdom, France, Germany,
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Editorial Office: 17, BLOOMSBURY SQUARE, W.G.
Publishing aqd Advertising Office : 5, SEQLE STREET, W.C.
LONDON: SATURDAY, JANUARY 23, 1897.
THE INCREASE IN LOCAL ASSOCIATIONS.
Probably not the least useful result of the labours of the
■energetic Secretary of the Proprietary Articles Trade Asso¬
ciation will prove to he the awakening or re-awakening of
the chemists and druggists in districts where local associa¬
tions have been non-existent, as they realise what a powerful
weapon is lacking in their never-ending struggle against the
■changing conditions of business. As Mr. Glyn- Jones had
•occasion to point out this week at Newcastle-on-Tyne,in a place
where a local association exists and deals with matters of
trade interest, nothing is simpler than the calling of a meeting
to deliberate upon any question of importance for the
time being. Failing such an organisation, however, the
■difficulties of ascertaining the opinion of the trade in a dis¬
trict are multiplied indefinitely. Mr. Glyn- Jones warmly
recommended his auditors, therefore, to take immediate steps
to combine for the local consideration of any and every topic,
the discussion of which may be followed by results of
importance to the members of the association as tradesmen.
The letter received from Mr. T. Maltby Claque, and printed
at page 80, shows that the seed has fallen on good soil, and
■everyone will join in the hope that a healthy and vigorous
plant may be the result.
Already two or three new associations, have thus been
started, qthers are in process of formation, and the dry bones
-are stirring in several of the time-honoured ones that have
been in the habit of meeting once a year for a dinner, and then
adjourning until the occasion of the next annual meal. If
this activity is maintained and the movement in the direction
■of union for trade defence continues, better things may
be hoped for with regard to the future of pharmacy
as a trade than have been indicated for some years past.
Let local associations be formed in every city and town,
federated to the extent that means shall exist for ready
inter-communication — so that any question of trade import¬
ance may be simultaneously discussed all over the country
and the results recorded at headquarters, where steps can at
once be taken to formulate and act upon those results — and
the protection of trade interests will be better assured than
is possible in any other way. The results already achieved by
the Plymouth and other specially active associations are in
themselves sufficient to prove the very great value of cordial
■co-operation amongst chemists and druggists, and the best
advice that can be given to any other association, new or old,
is to follow the example indicated.
At the risk of being accused of reiteration, though that
were a slight risk to incur if only the desired consummation
could be attained, we venture to assert that a local association
for the discussion of trade topics should be feasible
in every place where there are two or more chemists and
druggists. The less the number the simpler should it be to
arrange matters. Where only one exists, let hi nr occasionally
visit the nearest town or village where another is to be found,
and let the latter in turn call upon the first for a quiet chat.
If then they were to communicate with headquarters, in this
way even the most sparsely populated districts could be
organised and expressions of opinion be as readily obtainable
from remote corners as from the larger towns and cities.
As regards publication, the very nature of discussions on
many trade topics will of course always render it undesirable
to publish more than the outcome of the deliberations, if
even so much in some instances, but when anything take3
place which is worth putting on record, the columns of the
Journal are freely open for the purpose. Through the medium
of our correspondence columns, also, many questions of detail
may be threshed out and the work of local associations thus
be aided and facilitated. But the key to the whole situation,
so far as regards trade defence, is local organisation which
can then be supplemented by further action.
THE TRADE IN PROPRIETARY ARTICLES.
The tenor of some remarks by Mr. Weddell, at the
Newcastle-on-Tyne meeting, which do not appear in the
report at p. 75, was very encouraging from the pharmaceutical
point of view, for he was able to show from his own busi¬
ness experience that the proportion occupied by proprietary
medicines in the total business now done by his firm is much
less than was the case sixteen years ago. At that time, not
only did the sale of those medicines constitute a very large
proportion of the total business done, but profits being then
at high-water mark, that section of the business was a very
important one from a mere trading point of view. Now,
however, although the volume of business has increased con¬
siderably, the proportion of the turnover due to proprietary
medicines amounts to much less than half what it was
sixteen years ago, so that whilst profks have been reduced
the proportional amount of business done in those articles
has declined, whilst other branches have developed so as to
fill the gap and more.
Thus while the total business done has increased, the
portion which has come to bear little or no profit has
decreased, and there is good reason to believe that this is
not an isolated case, or even one of a minority. The trade
done by chemists as a whole has increased largely as the
public has gradually developed more wants, and no con¬
siderable proportion of this increase can have been due to
increased sales of proprietary medicines. Trade has increased
all round and growth has been less marked in the case of
proprietary medicines than with other goods supplied by
chemists and druggists. There may, perhaps, be fewer
brilliantly successful pharmacists to-day than a quarter of a
century ago, but the number engaged in the craft is very
much greater than it was then, while the average chemist and
druggist is almost certainly better off now than his prede¬
cessor at that time. How much more so he may be rests
largely with himself to decide.
72
pharmaceutical journal.
[Jan. 23, 18c7
ANNOTATIONS.
‘ Fossil Plants” will be the subject of the lecture at the next
evening meeting in London of the Pharmaceutical Society, and
the lecturer will be Mr. A. C. Seward, M.A., Examiner in Botany
to the Society. The date of the meeting is Tuesday, February 9,
and the chair will be taken by the President, Mr. Walter Hills, at
eight o’clock, precisely.
The School of Pharmacy Students’ Dinner, which is to take
the place of the annual Football Club Dinner, will be held in the
Duke’s Salon, Holborn Restaurant, at 7 p.m., on Friday,
February 26. The chair will be taken by Professor Greenish, and
it is hoped that all old students and others interested in the
School will avail themselves of this opportunity of showing their
continued interest in its work and progress. Tickets (5s. each)
may be had of the Hon. Secretary, Mr. T. P. Tebbutt, 17, Blooms¬
bury Square, W.C., to whom all inquiries should be addressed.
The Minor Examination Syllabus, explicit though it be, does
not seem altogether to carry conviction into the minds of students
preparing for the examination. There appears to be a lurking
suspicion that the words used in the syllabus imply more than they
express, and that what is actually expected by the examiners is
much more than is directly stated. Attention has been especially
directed to the existence of some such feeling as this, owing
to doubts having been expressed by students whether depen¬
dence could be placed upon the advice given in the note on
‘‘The Study of the B.P.” that appeared in the Journal for
January 2 (ante, p. 10), and referred to the extent to which
candidates should commit to memory the proportions of ingre¬
dients in official preparations. But there is no reason whatever for
such scepticism, for the Pharmacy Syllabus distinctly limits the
candidate’s “knowledge of the proportion of active ingredient or
crude material in official preparations ” to those containing —
Aconite, antimony, arsenic, belladonna, Calabar bean, cantharides, hydrate
of chloral, chloroform, caustic potash and soda, colchicum, digitalis, elateri.
mim, ergot, iodine, iodoform, ipecacuanha, lead, mercury, mix vomica, opium,
phosphorus, scammony, stramonium, squill, alkaloids and alkaloidal salts.
The limited time available for study in the case of many pharma¬
ceutical students renders it particularly necessary that they should
not waste any of it by the performance of unnecessary tasks,
or burden their minds with useless lumber, and it was with the
object of checking the tendency in this direction that the note
was published. Whilst it should be quite clear that a candidate
is none the worse off for knowing more than is specified in the
syllabus — indeed, for his own sake, he will be wise to learn a great
deal more — when preparing for the examination he should adapt
his course of study to the requirements of the Boards of Examiners,
and regard what is mentioned in the syllabus for the time being
as a fixed minimum. But above all else candidates should be
reasonable, and give examiners credit for the possession of common
honesty, rather than assume them to be capable of the merest trickery.
The Arsenical Soap Case, in which Mr. J. W. Taplin, Presi¬
dent of the Western Chemists’ Association of London, was the
defendant, has terminated — though only provisionally, perhaps —
in a manner that can give little satisfaction to either party. It
will be remembered that Dr. Thomas Stevenson failed to find any
arsenic in the sample sent to him, and the case was adjourned to
enable the defendant to submit the matter to the Somerset House
authorities. The result of this further analysis (see p. 78) is
indecisive, the small sample of soap not sufficing for the
application of exhaustive tests. It was clear, however, that
the arsenic, if present at all, could be only in inappreciable quantity ,
and Dr. Stevenson’s opinion was therefore confirmed. But the event,
proved that the prosecution would have been non-suited in any
case, for the magistrates — whilst inclining to the view that true
arsenical soap is a drug — followed- the Wimbledon precedent and
held that “arsenical” soap containing no arsenic could not be a
drug. The case was accordingly dismissed, with the remark that
proceedings should have been taken under the Merchandise Marks-
Act instead of the Sale of Food and Drugs Act, with which ruling
the preachers of the new crusade against arsenical soap are not
likely to be contented.
The Progress of Technical Education in Germany is the
subject of a report by Sir Philip Magnus and Messrs. Redgrave,
Smith and Woodall, who have visited that country as special
Commissioners on behalf of the British Government. It
is shown that Germany is rapidly progressing in those manu¬
factures in which superior knowledge and technical skill,
together with the application of chemistry and other sciences,
can be brought to bear. Nevertheless, it is pointed out the
aggregate value of Germany’s foreign commerce in comparison with
that of Great Britain has been over-estimated, though British
supremacy is seriously challenged. This is the case in spite of a
tendency to shorten hours of labour, German manufacturers being
of opinion that extended hours of labour react upon both the
quality and quantity of the output. The Germans are described
as appearing now to attach greater importance than ever to the
connection between higher scientific training and the development
of manufacturing industry, evidences being found of a determina¬
tion on the part of municipalities and the State to increase and
extend many schools, and to equip them with the most modern
and improved apparatus. Numerous instances are recorded to
show what great efforts Germany is making to come to the front
both in educational and industrial matters, under the conviction
that the nation which has the best schools is the best equipped
for commercial warfare. It is especially noted that the Merchandise
Marks Act as it now operates is said to be generally spoken of in
Germany as a strong weapon against England. The measure
is found to act as an advertisement of German industries, and
indicates to American and colonial buyers the true origin of much
that they had hitherto been in the habit of regarding as English.
Incandescent Gas Mantles appear likely to play, a very
important part in the immediate future of illumination by gas,
but their great value is to some extent counter-balanced by certain
disadvantages, mainly depending upon the colour of the light*
emitted by the combinations at present utilised in preparing them.
Mantles containing the oxides of zirconia and alumina, or alumina
alone excited by oxides of chromium, diffuse a warm pinkish-
yellow light, whilst others in more common use emit a cold
greenish-blue light. Professor Vivian B. Lewes thinks it possible
that the colour of the latter will prove to have a distinctly
injurious action upon the eyesight when continued over any long-
period of time. His opinion with regard to artificial illumina¬
tion is that a light to work by should be essentially
different from ordinary daylight and as free as possible from
actinic rays. When daylight disappears it is natural that the
optic nerve should be relieved by the periods of twilight and dark¬
ness, but if an artificial light be employed which is of a soft
character and poor in actinic rays, the eyes can be safely used for
some hours longer without risk of fatigue. On the other hand,
the continued use of artificial light rich in violet and ultra-violet
rays, such as is emitted by the more prominent mantles on the
market, may result in the course of a generation or so in gradual
Jan. 23. 1897]
PHARMACEUTICAL JOURNAL.
73
deterioration of eyesight. From this point of view, it would seem
that the acetylene light is particularly well adapted for artificial
illumination, for it is remarkably free from ultra-violet rays.
Workers with the microscope, too, will find here a definite reason
for preferring paraffin lamps as a source of light when working
after nightfall.
But Professor Crookes has shown that, whilst light more than
normally rich in violet rays contributes in time to a partial destruc¬
tion of the crystalline lens, and when excessive produces erythema
and symptoms resembling those of sunstroke, excess of yellow rays
temporarily destroys the erythropsine or photo-sensitive substance
of the retina, producing great fatigue of the nerve, and requiring
darkness for its re-formation and the restoration of normal vision.
The best form of artificial light, therefore, is one containing little
or no ultra-violet rays, no excess of yellow rays, and just sufficient
red rays to communicate a warm, pleasant tone to the surrounding
objects. The “Holophane” globe is recommended by Professor
Lewes for correcting the irregular distribution of rays from mantles,
and bringing the maxima of rays down to the working angles, the
surface of the globe becoming the light distributing medium.
Chemists and Druggists should be grateful to the Editor of the
Court Journal for defending the principle that special qualification
secured in the public interest is a thing to be valued and paid for
accordingly. Commenting on the fact that a protest against the
increase in the cost of medical advice has been followed in the
daily press by a tirade against the price of medicines, he observes
that people will always continue to prefer paying a price for their
medicines, which ensures the employment not only of pure
chemicals, but of men whose responsibility is undoubted. Even
though the statement may be correct that in very many instances the
medicine supplied costs less than the value of the bottle and cork,
the fact remains, it is observed, that the skill of the chemist must be
paid for, and it is this very skill that people are willing to pay for,
‘ ‘ for in it lies the comparative immunity from serious results by
wrongful administration of drugs.”
A Woman Chemist, who supposes she is “ something of a rare
specimen,” has waxed confidential with a Daily Chronicle interviewer
who, in turn, seems to have quite lost his heart to the “ bright
looking woman standing behind the counter of a tiny chemist’s
shop.” As a matter of course, not a specimen of dust was to be
seen anywhere in this Liliputian pharmacy, the proprietress of
which seems to have found her mission in tying up phials of
perfumes with “ wondrous bows and fancy finishes which might
well have figured on a Bond Street bonnet ” ; besides setting out her
powders, cosmetics, and “accessories” as prettily as a garden in
spring ; contending against the maleficent influence of the naughty
physicians who boycott women pharmacists on the ground that
their drugs cannot be of high quality ; and above everything else,
acting as consultant to ladies requiring the hundred and one little
appliances necessary for the sick-room and nursery, cosmetics,
ether draughts as “ pick-me-ups,” and so forth. Truly, an ideal
picture, this young man has sketched, but under the influence of
what kind of stimulant it is difficult exactly to say. As fleeting
in its effects as the ether draughts, let us hope.
The Fatality at Liverpool, reported briefly last week,
affords another instance of the risk incurred by the public in re¬
sorting to shops belonging to others than registered chemists and
druggists for medicines. According to the evidence at the in¬
quest, the deceased had visited the shop for the purpose of
purchasing a black draught. The individual in charge of the
premises was a boy of sixteen, and he appears to have taken the
bottle immediately above that containing the mist, sen me co. The
bottle taken down contained laudanum, and of this two ounces
was given to the unfortunate old man. The youth said, in reply
to a question, that when in the act of taking the bottle down he
turned to ask whether a strong or weak draught was required, and
that he then grasped the bottle “without looking towards the
shelf again.” The jury returned a verdict of “Death from misad¬
venture,” without casting any blame on the boy, but it is more
than questionable whether someone should not be held responsible
for such gross carelessness as was displayed, as it seems deserv¬
ing of the severest censure possible.
Hampstead’s Mineral Springs are apparently to be boomed
with determination, observes the Daily Telegraph, and if half of
the marvellous cures attributed to the waters by a local doctor be
true, Lourdes may yet have to defend its laurels. One spring has
been “ rescued from those iconoclasts who wished to turn it into an
ordinary fountain,” and it is reported that fresh chalybeate sources
have proved efficacious in combating “all sorts of maladies,”
whilst the fact that the London County Council has instructed its
analyst to examine and report upon samples of the waters has
raised high hopes among the residents that Hampstead may yet
become the Homburg of England.
The London Water Supply, as apart from these and other
mineral springs, is shown by Mr. W. J. Dibdin to have improved
greatly in quality between 1892 and 1895. But comparing the
waters now supplied, with Welsh waters, it is stated that the
organic impurity of Welsh unfiltered water is less than that of
average London filtered water, the former containing only 26
microbes per cubic centimetre, whilst London filtered water con¬
tains 167 in summer, and 298 in winter. The Kent supply,
however, contains only 90 in each cubic centimetre. These and
other facts recently placed before the Society of Chemical Industry
tend to encourage the notion that the public health would benefit
if Welsh water were brought to London.
The Pasteur Institute treated 316 patients in April, May,
and June last, and during those three months only six deaths
occurred. Rabies was apparently the cause of death in each of
the six cases, including two sent over from England. During the
previous three months only one death occurred out of 320 cases,
but it must be borne in mind that deaths often occur in one
quarter when the patients have been under treatment during the
previous one. The mortality of 1896, says the British Medical-
Journal, will come out higher than that of previous years, but in
all forms of admittedly imperfect treatment, like the Pasteur,
times of bad luck must come. The important point to remember
is, that during nine years the mortality has steadily diminished
under treatment from 94 to 13 per cent.
Postal Reforms designed to promote simplicity and uniformity
come into effect on February 1. The main features of these reforms
are the reduction of the surcharge on unpaid post-cards from two¬
pence to a penny, and of the fee on unregistered packets containing
jewellery, etc., from eightpence to fourpence, whilst the maximum
dimensions of letters and book packets are raised, the scales of com¬
mission on inland, foreign, and colonial money orders recast, and
various other small changes effected, which will tend to save much
annoyance now caused by numerous petty restrictions. Whether
anyone hankers after the receipt of letters measuring 2 ft. by 1 ft.
by 1 ft. may be doubted, but the abolition of much useless and
| irritating red tape is to be strongly commended.
74
PHARMACEUTICAL JOURNAL.
[Jan. 23, 1897
NEW IDEAS.
PHARMACEUTICAL SOCIETY.
STEAM BATH.
Franz Hering (Jena) manufactures a small steam bath for
heating infusion pots, etc. It is claimed as one of the principal
advantages of this little apparatus that with an ordinary Bunsen
burner it yields steam within half a minute. The large brass ring
shown in the illustration is hollow, and filled with water. The
central cylinder is arranged to contain only a small quantity of
water, which is therefore rapidly heated, the water level being
maintained from the supply in the reservoir.
A NOVEL COAL-BOX.
“ The Silent Coal-Box” has been devised by Mr. Fred Reynolds^
whose thirty-first invention it is, for the special benefit of invalids.
Its value will be fully
appreciated by every¬
one who has suffered
irritation from the
grating of coals as they
are coaxed out of an
ordinary coal-box which
might have been spe¬
cially designed for its
acoustic properties.
This “ Silent Coal-Box”
is made of almost inde¬
structible material, and will not wear out like the tin sheath
of the ordinary sounding coal-box. It should therefore prove
economical as well as counter-irritant. Messrs. Reynolds and
Branson, Leeds, lend a few of these “ Silent Coal-Boxes ” on hire
at a small charge per week or month.
NEW CAPPING MATERIAL.
Specially-prepared flare skins are being offered by Messrs.
James E wen and Sons, 5, Hatfield Street, S.E., for capping
bottles and pots. These skins are claimed to be better for the
purpose than French gut, and certainly they serve the specified
purpose extremely well. On soaking for a few minutes in cold
water they can be stretched considerably, and, if all superfluous
moisture be then wiped off, a satisfactory cap can be made, which
will dry within a reasonable time, stretched taut, and without any
creases. The price, too, is exceedingly moderate, as the skins are
supplied at ninepence per dozen.
COMPRESSED DRUGS.
Trional and tetronal tabloids (5 grains each) have been intro¬
duced by Messrs. Burroughs, Wellcome, and Co., to meet a
demand for a convenient method of administering these drugs.
Eucaine hydrochloride soloids (1 and 5 grains each) are also being
prepared by the firm.
DONATIONS TO THE LIBRARY AND MUSEUM.
At a meeting of the Library, Museum, School and House Com¬
mittee, held on Wednesday, the 20th inst., the Librarian presented
the following report of donations : —
To the Library (London).
The Surgeon-General, U. S. Army, Washington : — Index-Catalogue of Library,
2nd series, vol. 1.
Kaiserlieh-Japanische Universitat : — ' Mittheilungen,’ Band 3, No. 2, 1895.
Imperial Botanic Garden, St. Petersburg ‘ Acta Horti Petropolitani,’ tom. 15,
fasc. 1.
Messrs. E. B. Squibb and Sons, Brooklyn ‘Ephemeris of Materia Medica,’
vol. 4, No. 4.
H.M. Secretary of State for India :— ‘ Flora of British India,’ No. 22.
Yorkshire College, Leeds ‘ Twenty-second Annual Report,' 1895-6.
Dr. Louis Planchon, Montpellier : — ‘ Les drogues recemment inscribes au Codex,
1896, two pamphlets ; ‘ Le commerce actuel de l’herboriste dans une region
du Languedoc,’ 1896.
Mr. Thomas Christy, London : — ‘ New Commercial Plants and Drugs’, No. 12, 1897.
Mr. Wm. Copney, London Ure’s ‘ Dictionary of Arts,’ 3rd ed. ; Turner's.
‘ Chemistry,’ 8th ed.
Professor Oliver, F.R.S., Kew : — Daniel Hanbury’s MS. Notes on Amomum.
Journals, etc., received duriDg 1896 : — ‘ Archiv for Pharmaci og Chemi ’ 7.
‘Bulletin de l’association beige des chimistes * ; ‘ Botany Bulletin,’ Queens¬
land ; ‘Agricultural Ledger,’ Calcutta; ‘Agricultural Gazette of N.S.
Wales’ ; ‘ Zeitschrift des allgemeinen Osterreichischen Apotheker-Vereines’ ;
1 Alumni Report,’ Philadelphia; ‘ American Druggist ’ ; ‘American Journal
of Pharmacy’; ‘The Analyst’; ‘Australasian Journal of Pharmacy ’ 7
‘ British Medical Journal ’ ; ‘ Canadian Pharmaceutical Journal ’ ; ‘ Chemical
News’ ; ‘Journal’ and ‘Proceedings of the Chemical Society’; ‘Chemist
and Druggist ’ and ‘ Diary ’ ; ‘ Journal of the Linnean Society ’ ; ‘ Memoirs
and Proceedings of the Manchester Literary and Philosophical Society ’ 7
‘Pharmaceutical Journal of Australasia’; ‘Quarterly Record of the Royal.
Botanic Society’; ‘Kew Bulletin’; ‘Proceedings of the Royal Society ’7
‘ Sei I-Kwai Medical Journal ’ ; ‘ Journal of the Society of Chemical
Industry’; ‘Tlmehri’; ‘Western Druggist’; ‘Anzeiger’ and ‘Sitzungs-
berichte,’ Kaiserliche Akademie der Wissenschaften in Wien.
To the Library (Edinburgh).]
Professor Fraser, M.D., F.R.8., Edinburgh : — ‘ Bone-Marrow in the Treatment of
Pernicious Anaemia ’ ; ‘The Limitations to the Antidotal Power of Anti¬
toxins ’ ; ‘ Bichromate of Potassium as a Remedy in Gastric Affections ’ ;
‘ The Remedies Employed in Cardiac Affections and their Indications ’
‘ Immunisation against Serpents’ Venom and the Treatment of Snake-bite-,
with Antivenene ’ ; ‘Serpents’ Venom, Artificial and Natural Immunity:
Antidotal Properties of the Blood-Serum of Immunised Animals and of
Venomous Serpents’; ‘Preliminary Notice on the Arrow-Poison of the
Wa Nyika and Other Tribes of East Equatorial Africa, with Special Refer¬
ence to the Chemical Properties and Pharmacological Action of the Wood
from which it is Prepared.'
Mr. James Thin, Edinburgh : — ' Edinburgh Royal Infirmary Pharmacopoeia,,
2nd ed., 1896.
Mr. William Burley, Edinburgh : — ‘ Pharmaceutical Journal,’ 65 parts, 1863-70.
Journals, etc., received during 1896 : — ‘ Alumni Report,' Philadelphia ; ‘ Austra¬
lasian Journal of Pharmacy’; ‘Pharmaceutical Journal of Australasia’ ;.
‘ Anti-Cutting Record.’
The following donations were reported by the Curator : — ■
To the Museum (London).
The African Lakes Co., Glasgow : — Fruits of Strophanthus lcombe, Oliv.
Professor J. B. Balfour, M.D., F.R.S., Edinburgh: — Gum resins of Balsamoden-
dron socotranum, Balf. f . , and oleoresin of Boswellia socotrana, Balf. f.
Messrs. Wright, Layman, and Umney, London: — Persian Fennel Fruits.
Messrs. Evans, Lescher, and Webb, London : — Flowers of Cereus grandiflorus,
Mill.
Mr. R. T. Baker, F.L.S., Technological Museum, Sydney :— Fruits of Cassia
brewsteri, F. v. Mull.
To the Museum (Edinburgh).
Messrs. Hodgkins m, Treacher, and Clarke, London :— False packed Lima
Sarsaparilla.
Messrs. Wright, Layman, and Umney, London :— Persian Fennel Fruits.
Mr. J. Rutherford Hill reports that the Royal College of Physicians has finally
ratified the transference of their Materia Medica Museum to the Pharmaceutical
Society of Great Britain, and that the Scoresby-Jackson Materia Medica Collec¬
tion has been purchased for £45, in accordance with the arrangement made by
Mr. Ewing, on behalf of the Society.
Jan. 23, 1897]
PHARMACEUTICAL JOURNAL.
75
THE WORLD Op PHARMACY.
- - ♦ -
BUSINESS MEETINGS.
Edinburgh Chemists’ Assistants,’ and Apprentices’
Association, Friday, January 15. — Mr. James McBain,
President, in the chair. — The first paper read was by Mr. Peter
Boa, on —
Chloroform Water.
The author said it had been alleged that the chloroform water of
the B.P. did not keep well, and he had conducted some experiments
to test the point both as to keeping qualities and taste. In
October, 1894, he prepared three solutions : No. 1 was the chloro¬
form water of the B.P., and contained chloroform, itlxv., and dis¬
tilled water, 6} fl. ounces ; No. 2 was a similar solution, to whiph
3ii. of rectified spirit was added ; No. 3 was made by using an
equivalent quantity (3v.) of spirit of chloroform. The solutions
were placed in partially-filled corked bottles, kept in the pharmacy,
and opened several times weekly for about six months, and then
about once a month up till the present date. The taste
of 1 and 2 was at first nearly alike, but 3 was not
so nice. Gradually 2 and 3 deteriorated in taste and
became less palatable. At the end of the time (2£
years) 1 was still in a quite usable condition ; 2 and 3
had to a considerable extent lost the characteristic flavour.
1 had an acid reaction, and gave a distinct cloudiness with silver
nitrate. 2 and 3 were neutral and gave a faint haze with silver
nitrate. Spirit of chloroform, in perhaps three-fourths of the
mixtures in which it is prescribed, is added merely for flavouring
purposes, and he thought this end would be better attained by
using chloroform water. The cloudiness with silver nitrate in 1
seemed to indicate a slight decomposition, and 2 and 3 seemed to
indicate some preservative effect, due to the alcohol, but the loss
of flavour was not explained.
The next paper was by Mr. C. A. Macpherson, on —
An Adulteration of Pimento.
Pimento is described in the B. P. as being of a dark brown colour.
While this is correct in a general way, yet, as usually seen in
commerce, it is a mixture of various shades, ranging from a grey
brown to a very dark brown. A few months ago, however, a
sample came into my possession in the ordinary course of trade
which differed very much from any I had previously seen. It was
of a reddish colour, and though somewhat resembling the shade of
some of the berries occurring in ordinary parcels, it still seemed
different and was too uniform in tint not to arouse suspicion. On
closer examination it was seen to have a dull earthy appearance,
and when viewed through a lens brown patches could be seen on
the berries, particularly near the ring formed by the remains of the
calyx. It was found that the colour could be removed by washing,
was insoluble in water, and very slowly acted upon by hydrochloric
acid. A small quantity having been obtained, and a solution formed,
potassium ferrocyanide was added, with the result that the
blue colour indicative of a ferric salt was obtained. It was
evident that the colour was due to ferric oxide, probably in the
form of- Armenian bole. I am informed that the dealers from
whom the sample was obtained, on being asked, stated that some
of their customers wanted it coloured. Be that as it may, anyone
selling the sophisticated article would probably be made to suffer
if the stuff found its way into the hands of a public analyst.
While it may be necessary for us at times to have iron administered
to us, I think we ought to be allowed to take it in some other form
and not be forced to swallow it in the form of Armenian bole,
either in our sausages or with our condiments.
The next paper was by Mr. J. Rutherford Hill, on—
Belladonna Plasters.
Mr. Henry’s recent paper on “ Uniformity in Pharmacy” indi¬
cated that there was a difference in practice in Edinburgh as to
what should be supplied when belladonna plaster was prescribed.
The author had recently had brought under his notice a series of
seven different types of belladonna plaster, all of which had been
supplied in the ordinary way in various places when a belladonna
plaster was asked for over the counter. An examination of these
revealed an even greater variety, as will be seen by the follow¬
ing : —
No. 1.— American, rubber basis, no lead, spread on felt, dark green, relatively
high proportion of atropine.
No. 2. — American, rubber basis, no lead, porous, spread on muslin, dark green,
relatively high proportion of atropine.
No. 3. — English, like rubber basis, but more resinous, no lead, porous, spread
on muslin, light bright green, contained no alkaloid.
No. 4. — English, similar basis to No. 3, but contained lead, porous, spread on
muslin, very dark green, contained no alkaloid, labelled poison.
No. 5. — Spread on leather, soap and resin plaster basis, dark olive-green,
medium proportion of atropine, apparently the belladonna plaster of the 1867
Pharmacopoeia.
No. 6. — Spread on leather, soap and resin plaster basis, very pale olive-green,
small proportion of atropine, labelled jpoison.
No. 7.— The official brown-coloured plaster spread on leather, more than
medium proportion of atropine, labelled poison.
Thus in every instance a different article was supplied, and only
in one case in seven was the official plaster supplied. It seemed to be
undoubtedly the case that the public desired the green plaster, and
it was rather interesting to note that the U.S.P. of 1890
had reverted to the green plaster, and some recent work by
Mr. Naylor indicated a similar tendency in this country. There
had been many complaints as to the present B.P. plaster.
It was said to be much too soft, and Mr. Boa had
suggested a new formula to meet this objection (Wear
Book,’ 1895). He observed that when the plaster
made from the root extract was first introduced by Mr. Martindale
at University College, he used lead plaster alone as the basis, and
he thought that would give a firmer plaster. There had also been
several complaints that the plaster produced an eruption or
blister. Gerard mentioned a similar complaint about the leaf ex¬
tract plaster, but such complaints had been much more common
since the 1885 B.P. form was adopted. This result was attributed
to the plaster being too strong in atropine, but some of the rubber
basis plasters were as strong, or stronger, and no complaints had
been made about them. In the case of two of the seven samples, no
alkaloid at all was present, and this would be awkward for the
seller if the public analyst appeared on the scene.
Pharmaceutical Society of Ireland. — Registered Druggist
Examinations : — Mr. R. N. Allen passed. Three candidates were
rejected. Pharmaceutical Licence Examinations : — Messrs. W.
Yeats, J. F. O’Neill, G. A. Deans, W. H. Hopkins, J. W. Carr,
and J. M. Whelan, passed. Nine candidates were rejected.
Proprietary Articles Trade Association (Newcastle-
on Tyne), Thursday, January 14. — Mr. G. Weddell in the chair.
— There was a large and representative attendance, those present
including Mr. L. Arrowsmith, Byker ; Mr. G. F. Merson, New¬
castle ; Mr. R. Wright, Byker ; Mr. Radford, Newcastle ; Mi1.
T. M. Clague, Newcastle ; Mr. C. Ridley, Newcastle ; Mr. Ord,
Gateshead ; Mr. F. R. Dudderidge, Newcastle ; Mr. Rose, Jarrow ;
and Mr. R. H. Bell, Sunderland. — The Chairman, in introducing
Mr. Glyn-Jones, said he believed that the proprietary medicines’
question, so far as chemists were concerned, was not so serious as
it had been, because those articles had ceased to be a source of
livelihood for them. They did not rely upon the proprietary medi¬
cine trade, having learnt by bitter experience to do without the
profits on those preparations. Therefore, while they were met to
see what could be done in order to regulate the prices of those
things to prevent outrageous cutting, and, if possible, to establish
a uniform selling price, still, it was not a matter of life or death
to them. They were now existing without any profits on
proprietary medicines, and they would continue to exist
whatever steps were taken. The serious part of the
business was the cutting in drug stores, and he believed
the demand for cheap goods had caused deterioration in
the quality of drugs supplied in many places. They had to decide
what attitude they would take in regard to the question of cutting
prices. He had a perfectly open mind on the matter. He had not
followed very closely the movements of the Association, but would
like to say that a closer association of the chemists in Newcastle
had been attempted but had failed, sometimes for one reason and
sometimes for another. He did not think, however, that such an
association was at all impossible. If they could get such a meeting
as that for a quiet talk once in three months, he thought they
might understand one another better and sympathise with one
76
PHARMAGETJTIGA L JOURNAL.
[Jan. 23, 1897
another better than they did at present, and not run away
with the idea that they were intent on cutting each other’s
throats.
Mr. Glyn-Jones read letters from Mr. B. S. Proctor, Mr. James
Davidson, Mr. Baker (Gateshead), Mr. Whitehead (Whitley), and
Mr. Rheeder (Newcastle), who regretted absence and expressed
entire sympathy with the objects of the Association. He further
stated that he had called upon several chemists in Newcastle that
day, and that Mr. Bolam and Mr. Forster had joined the Associa¬
tion. He was glad to see such an excellent meeting of chemists in
Newcastle and district, more especially because of the somewhat
unusual difficulty they had had in calling that meeting. Un¬
fortunately for Newcastle it was one of the large towns
where no chemist’s association existed. He could assure them that
the importance of local associations had been brought very promi¬
nently before him in connection with this work, as by their means
trade meetings could be called with far greater ease than when there
was no local association. The Chairman had told them of the difficul¬
ties experienced in trying to form an association in Newcastle. His
experience with the trade throughout the country convinced him
that one of the most powerful motives for combination lay in the
questions which affected their trade interests. There could be no
doubt that the most promising associations they had in the country
were conducted and officered by men who were alive to their
interests as retail chemists and druggists. The question now
before them was a trade question, and that it had been the means
of bringing together such a meeting proved his contention. If he
found from that meeting that there was a tendency to support the
Association he would be sorry to leave Newcastle without
some step being taken to form a local branch. The Chair¬
man had said that this question was not so serious as it
had been sixteen years ago. He did not know what
the state of affairs had been, but if it had been worse than it was
to-day he was more than ever surprised that some attempt had not
been made to stem the tide. The sale of proprietary articles
affected them mostly, and their action in preventing cutting had a
two-fold aspect. One was to guarantee a fair profit upon proprie¬
tary articles, and surely it did not want any argument to prove
that they would all benefit by having guaranteed profits. Then
there was the question of establishing uniform prices. No doubt
the crux of the matter was this : the drug stores and cutters
were robbing chemists of their business and fleecing
the public by making use of proprietary articles as a
draw, and by using them to prove the statement, which they
had no hesitation in making, that the ordinary retail chemist was
exorbitant in his charges. No doubt the public had no idea
of the ratio of chemists’ expenses to their turnover, and no
idea what chemists took in a week, or how that compared
with what was taken by a grocer or a draper. The public,
therefore, had no idea what chemists’ working expenses were.
Moreover, trade opponents endeavoured to prove that the
charges of chemists were exorbitant, and if chemists
could take away from their strongest opponents this weapon,
a very useful purpose would certainly be served. As
to how that object was to be attained, it was obvious
that any plan for preventing cutting in connection with
proprietary articles must have the active support of the pro¬
prietor, and, in order to get that support, they must
show the proprietor that what they were working for would be to
his interest. He did not think the raising of prices would decrease
the demand for proprietary medicines, although in reference to
luxuries he was prepared to admit that prices had a considerable
effect upon the demand. But though the proprietor might create
a demand, he had to rely upon the assistance of a certain body of
traders for his goods reaching the public, and they were able to
show, beyond doubt, that the retailer was now in a
position to exert a vast amount of influence for good
or for bad upon the sale of proprietary articles. No
man, whether chemist or grocer, was prepared to distribute
other people’s proprietaries without profit. They had already a
list of between thirty and forty articles, in regard to which an
agreement had been made between the proprietor and the retailer,
and the arrangement was working successfully. The objection
that their list did not include articles of the largest sale was ex¬
ceedingly unreasonable. They had made a man a present of the
profits upon forty articles, and he objected to support the Associa¬
tion because they had not guaranteed him a profit upon the
largest. And that objection came from gentlemen who
had done least in helping to accomplish the work they had done.
If the rank and file of the trade had been half as much irs
earnest in supporting the Association as some had been in
opposing it, they would have carried this thing to an issue.
With regard to proprietors, if they looked the matter fairly
in the face, they would realise that any little ill effect which
the raising of prices might have, would be more than counter¬
balanced by their having the cordial goodwill and support of
the retail trade. As to the prospects of the Association,
that body depended almost entirely upon the amount
of support which the retail trade gave it. In conclusion
stress must be laid upon the importance of prompt
action. The great obstacle in the way of getting proprietors to
come upon their side was the fact that their opponents had been
able to say that their Association did not speak for the retail
trade. They now had with them the great bulk of the wholesale
trade, and there would be no difficulty in getting the rest if the
retailers would make it plain that it was their wish that the whole¬
sale firms should support this movement. Some ten or eleven
houses had already promised £550 as a guarantee fund.
»Mr. L. Arrowsmith moved —
“ That this meeting of chemists in Newcastle and district cordially approves
of the proposals of the Proprietary Articles Trade Association, and strongly
urges upon proprietors the advisability of adding their articles to the-
protected list,”
and spoke at length on the manner in which drug stores conducted
their business, and the advantages attendant on the system
followed. — Mr. Rose (Jarrow) seconded the resolution. He said he
had been an ardent supporter of the Association from its conception,
and had great faith in its ultimate success, provided retailers
would act at once and together.
Mr. T. M. Clague (Newcastle) said the chemist as well as the
store man would be compelled to raise retail prices by such an
organisation as this when they got a majority. There were 9000,
and when they got something like 6000 or 7000 they would be able
to say to these men, “ You are not going to charge us 11s. 6ri. per
dozen unless you say we are going to get Is. l^d.” The crux of
the situation lay in the one word “combination.” If the P.A.T.A.
was not worked on the best lines, though it probably was, they
ought to give the benefit of their adhesion and encouragement,
then work it on such lines as would be effective. The question was.
Were they able to do more singly in dealing with the individual
recalcitrant proprietor or when they went to the latter era masse ?
Combined, they could do a great deal, whereas as individuals they
were as ropes of sand. Ever since the Association was started he
had recognised in it an honest attempt to deal with what he felt to
be a difficulty. He felt that there were elements of danger in the
question ; thus : there was a danger that they might in some in¬
stances ask too much. Unfortunately, there was a little bit of the
strain of Oliver Twist in the drug trader. For instance, they were
to blame if they asked 50 per cent, for handling a drug. The
difficulty had arisen from that. It gave the cutter a look in, which
he would never have had otherwise. It would not be right to
expect 50 per cent. , though, of course, they must have a margin for
credit business. The cash customer was entitled to some considera¬
tion, and in that respect the stamp value was very handy. They
(the chemists) were entitled to an additional threehalfpence when a
sale had to go into their books. He thought they, should have
something more to offer than they had at present before they nego¬
tiated with the proprietor, and he trusted there would be no hang¬
ing back, but that the meeting would unanimously pass the resolu¬
tion, and everyone present associate himself with the P.A.T.A.
He hoped they would also look after those who were not present,
and see that they gave their adhesion, as he believed there were
some men on the cutting side who would be glad to find an easy
and safe path to the other side. Let them take it that these
men were willing, whatever they had done in the past, to
co-operate with them in securing a better profit on proprietary
articles.
Mr. Radford said a great diversity of opinion existed through¬
out the country regarding this movement ; but he thought every
one should support this Association, because they would g et no
better opportunity. — Mr. Wright thought this a step in the right
direction, and one of the most pleasing things was the fact
that the proprietors were prepared to join the Association
as soon as they saw the trade was united upon the matter.
He thought that they in Newcastle at all events would be going
against their interests if they did not support this movement.
— Mr. Glyn- Jones subsequently replied to several questions, and
JAN, 23, 1897]
PHARMACEUTICAL J TURN AX .
//
the resolution was then put and carried. — Mr. Clague was ap¬
pointed to convene a meeting of Newcastle and district chemists,
with a view to a branch of the Association being formed.
Proprietary Articles Trade Association (Sunderland),
Wednesday, January 13. — Councillor John Harrison, J.P.,
Vice-President of the Pharmaceutical Society, in the chair. — This
meeting of the chemists and druggists of the district was called by the
Sunderland Chemists’ Association to consider the proposals of the
P.A.T.A., and amongst those present were Messrs. R. H. Bell,
T. D. Pattison, J. S. Bowman, C. Hodgson, J. F. Weightman,
W. J. B. Blyth, J. G. Sutherland, T. Walton, E. R. Cherrett,
C. Thompson, W. Bowness, A. W. Golightly, T. B. Nicholson,
J. G. Harrison, M. J. Todd, E. J. Harrison, and H. C. Harrington.
— The Chairman said that he was not present as representing the
Pharmaceutical Society, but he presumed he had been asked
to take the chair as being one of the oldest chemists in
the town. The position was one which must be faced fearlessly
and clearly. Competition in proprietary articles had become
unfair, and they could not hope to meet it by individual efforts,
but by effective combination. They were there to view the matter
as tradesmen, and it would be undoubtedly an advantage to secure
uniform prices for proprietaries. The cutters had used this in
order to give the public an impression that as a trade chemists
were exorbitant in their prices. He thought every chemist ought
to become a member of the P.A.T.A. — Mr. Glyn- Jones then dealt
fully with the history of the Association, showing its aims and its
proposals for the future. In doing so his address was very much upon
the lines of the article written by him, which appeared in the Pharma-
ceutical Journal for January 9 {ante, p. 23). He pointed out the diffi¬
culties experienced in carrying out individual agreements, showing
from this the importance of having a combined plan. He mentioned
some firms with great resources at their back who had been unable
so far to defeat the Association. He strongly condemned the
practice, which he said was far too common, by which chemists
were gratuitously advertising unprotected articles, and he
earnestly appealed to the leaders of pharmacy to support the
movement for the sake of their less fortunate brethren, who,
though they were not in possession of high-class dispensing busi¬
nesses, were yet serving a useful purpose. — Mr. Bell then moved .
“ That this meeting of chemists residing in Sunderland and district cordially
approves of the proposals of the P.A.T.A., and urges upon all proprietors the
advisability of adding their articles to the protected list.”
Mr. Todd seconded this, and said that from 30 to 50 per cent, of
•chemists’ takings were for proprietary articles, so that the question
was of vital importance to them. No pharmacist could afford to
ignore the question, and so far as he had been able to gather, all
his trade friends spoke in support of the movement. It was now
their duty to force the hands of such proprietors as were sitting on
the fence, and to get them to declare their position. — Mr.
Weightman said his experience was that where prices were main¬
tained the public were willing to give them, and he thought
-that if chemists joined the Association they would
eventually get what they were seeking. — Mr. Cherrett
wished to know what would be done in the case of chemists
who, after promising to maintain prices, obtained large
supplies, and then commenced to cut. — Mr. Walton said that they
should have at least 15 per cent, minimum profit. — Mr. Todd
agreed that this was fair on articles of every-day use, but in the
case of medicine it should be 25 per cent. — Mr. Blyth said
that whatever the profit allowed was, the article should be
sold at the advertised price. — Mr. Glyn- Jones, in reply, said that it
was essential that their demands as to the amount of profit should
be reasonable and that they should be able to show the public that
their demands were but just and not extortionate. Various classes
of goods should show better profits than others. If there was any
doubt about the bona fides of a trader a special agreement en-
forcable in a Court of Law would have to be made. If they wished
the least increase they must remember that it would only be so in
proportion to the amount of support received from the retail trade.
The resolution was carried unanimously, and also a motion asking
the Sunderland Association to act as local executive of the P.A.T.A.
— The Chairman, in replying to a vote of thanks, said he felt more
.strongly than he did when he came to the meeting that they were
taking part in a movement, which, .if supported as it should be,
would do a great deal for the retail chemists of this country. He
warned them, however, against thinking that the enthusiasm of
the movement would be sufficient for their purpose. It required
their whole energy and persistent effort. Proprietors would not
co-operate with them until they found that they were thoroughly
united in their demands, and that they were determined to obtain
their just rights.
SOCIAL MEETINGS.
Liverpool Pharmaceutical Students’ Society, Thurs¬
day, January 14. — The seventh annual dinner of this Society took
place at the Alexandra Hotel, Liverpool, the Vice-Presidents,
Messrs. H. S. Peirson and H. B. Morgan occupying the posts of
Chairman and croupier respectively. After an excellent dinner,
served in good style and partaken of by a company numbering
upwards of fifty, a lengthy list of toasts, interspersed with vocal
and instrumental music, was entered upon, occupying the time
very pleasantly until nearly midnight. The oratorical honours of
the evening were divided among Mr. F. C. Larkin, F. R.C. S., who
replied to the toast of “ The Medical Profession,” Messrs. R. H.
Mitchell and John Smith (local secretary for the Liverpool district),
the proposer and responder to the toast of “The Pharmaceutical
Society,” Dr. Logan and the Chairman for “ The Students’ Society,”
and Mr. Charles Sharp, F.L.S., in proposing “The Visitors,” with
the reply by the students’ old friend, Mr. Edward Davies, P.I.C. ,
F.C.S. The arrangements reflected great credit upon the Secre¬
tary, Mr. P. H. Marsden, F.C.S. , and the Treasurer, Mr. R. H.
Mitchell, to whose exertions the success of the affair was to a great
extent due.
Chemists’ Assistants’ Association, Thursday, January 14.
— Mr. Charles Morley, President, in the chair. — The second half
of the session was opened by a musical and social evening, under
the direction of Mr. H. H. Robins. An excellent programme, con¬
sisting of songs, humorous and otherwise, recitations, pianoforte
solos, etc., was rendered by several of the members and friends,
and was greatly appreciated, Mr. A. Lilly accompanying. During
an interval refreshments were provided, and on resuming the pro¬
gramme Mr. C. E. Robinson proposed and Mr. F. Cooper seconded
a hearty vote of thanks to all who had assisted in the entertainment.
This was carried with acclamation, and a very pleasant evening
was concluded by singing the “ National Anthem.”
LEGAL INTELLIGENCE.
PROCEEDINGS UNDER THE FOOD AND DRUGS ACT.
The Sale of Arsenical Soap.
At Richmond Petty Sessions, on Monday, before His Worship
the Mayor and other justices, J. W. Taplin, of Station Parade,
Kew Gardens, chemist and druggist, appeared to an adjourned
summons for having sold arsenical soap not of the nature and sub¬
stance demanded. Mr. J. H. Gould prosecuted on this occasion,
and Mr. A. Hutton, barrister, appeared to defend.
The report of the former proceedings will be found at page 561
of last volume. As the case stood, an adjournment had been
granted so that a portion of the tablet might be taken to Somerset
House for analysis. The facts briefly were : — An assistant to
Inspector Houghton, one of the Surrey County Inspectors, pur¬
chased, for 6 d., a tablet of “Dr. Mackenzie’s Arsenical Soap,”
which was subsequently sent to the analyst, Dr. T. Stevenson, who
certified in the following words : — -
“ I am of opinion the sample contains soap free from arsenic, 100 per cent.”
Dr. Stevenson, in supporting his analysis on oath, declared that
arsenic was useless as a preparation for the skin, and it could not
do what the advertisement of the soap said it could : viz. , ‘ ‘ Have
a marvellous effect on the skin, and prevent the growth of super¬
fluous hair,” nor would it “ nourish and whiten and benefit the
skin. ” The defence set up was that this article was not a drug,
but the Bench overruled it, and then defendant availed himself of
the right to have the second moiety sent to Somerset House for
independent analysis.
The Clerk of the Court announced he had received the following
letter : —
78
PHARMACEUTICAL JOURNAL.
[Jan. 23, 1897
Government Laboratory,
Somerset House, London.
Sir, — The sample of arsenical soap referred to in your letter of December 17,
1896, marked “A 227,” was duly received securely sealed. From the contention
of the prosecution and the defence, it is evident that arsenic, if present at all,
must be there in a very minute quantity, and in view of the very small sample
sent, a series of experiments has been made on soap mixed with arsenic as
sodium arsenite, to discover the most trustworthy method for its detection in
small samples. After a careful investigation, we find that the sample referred
to, which weighs only 293 grains, would be quite insufficient to enable us to
determine, with certainty, whether it contains arsenic, if, as is alleged, the
amount does not exceed l/100th grain of arsenious oxide to the pound.
I am, Sir, your obedient servant,
B. Bannister
Mr. Hutton said upon that letter and upon the finding of the
Bench upon the last occasion that arsenical soap was a drug, he
should not contest the ruling any further upon that analysis. His
client had exercised his rights under the Act, and had elected to
take the independent certificate of the Government department,
' but he must abide by its decision. Although it was a chemist who
was the seller, and therefore summoned, he was there in con¬
sequence of instructions from Mr. Harvey, the manufacturer of the
soap. Soon after one or two prosecutions in respect of this soap
took place, Mr. Harvey had a careful analysis made, and it
appeared in that particular batch there was, by some reason, little
or no arsenic. Although he had evidence that arsenic was given
out by Mr. Harvey for the purpose of being put into the soap, he
knew the Bench would rule against him, so he would not tender
such testimony. The manufacturer had, however, done all in his
power to comply with the law. He had caused advertisements
to be issued desiring all chemists to return to him their stock
of Dr. Mackenzie’s arsenical soap in exchange for some
made under a different formula, and promising to indemnify
against prosecution all who responded to the request. He had
also promised to give a warranty with the new packets. He at
once recalled the soap that was out, and he desired that these facts
should be laid before the Court. He asked that a light penalty
might be imposed on the defendant, as they had endeavoured to
comply with the ruling of the Bench.
Mr. Gould intimated he did not press for a heavy penalty, and
the prosecution did not suppose the defendant sold the soap other¬
wise than as he received it from the manufacturer.
After the Bench had privately deliberated, His Worship said
when the Bench came to the conclusion that arsenical soap was a
drug they did so upon the ground that it contained arsenic.
Since it had been proved that it did not contain arsenic it ceased
to be a drug, therefore they dismissed the summons upon the
ground that it was under the wrong Act.
Mr. Gould asked that the decision might be adjourned until the
decision of an appeal pending on the same point.
Aid. Burt : You should have asked that earlier.
The Bench refused to accede to the request, but intimated they
would state a case.
Inspector Houghton asked for a summons against other chemists
who had sold similar soap certified to contain no arsenic, but the
Bench intimated that it would be better to wait the result of the
appeal.
OBITUARY.
Skirrow. — On October 26, William Skirrow, Chemist and
Druggist, of Bingley, Yorks. Aged 32.
Howson. — On January 16, Thomas J. Howson, Chemist and
Druggist, of Gateshead-on-Tyne. Aged 77.
Venman.— On January 16, Hezekiah Yenman, Chemist and
Druggist, late of Pimlico. Aged 65.
Blanshard. — On January 18, Thomas Blanshard, late of the firm
of Raimes, Blanshards, and Co., Edinburgh. Mr. Blanshard was
born at Kelfield, Yorkshire, in 1820, and went to Edinburgh in
1832, where he served his apprenticeship with John and Richard
Raimes and Co. In 1839 he became traveller for, and partner in the
firm, and was well known both in England and to the extreme
North of Scotland. He retired from the firm about twenty years
ago, and at the time of death was aged 77.
CORRESPONDENCE.
The Benevolent Fund.
Sir, — That the Fund is in so low a condition is not only a
source of regret but of serious apprehension — and although the
cause is apparent, the means of relief are not forthcoming. Now
can no plan be devised to meet the exigency of the case? No
spasmodic effort is of permanent avail. That far-seeing benevo¬
lent man John Wesley secured the permanency of his society by a
very simple method — every member is required to contribute a
penny per week and a shilling four times a year. From this
source alone all the working expenses of the vast machinery of
Wesleyan Methodism is supported. Reckoning the number of
chemists and druggists at 12,000, each subscribing five farthings
weekly would produce an aggregate sum of £2500 per annum. He
must be poor indeed who could not put by so minute a sum, even
by denying himself half a pint of ale. The amounts might be
collected by the local secretaries, who would thus be brought into
contact with members, and in case of unforeseen misfortune afford
immediate relief. Applicants for annuities being personally
known to the secretary, he might report to the committee and the-
grant graduated to circumstances. This would obviate the-
expensive method of voting, and also do away with the touting
system, besides which there would be no hint of charitable
grindery ; each man claiming as a right what he had helped to
maintain. And I beg to suggest that accumulated wealth would be
in a few years sufficient to endow a comfortable home for the life-
worn man of drugs, who might there spend the evening of his
days associated with his companions of long past years, spent in
the activities of scientific and business engagements.
Kew, January 13, 1897. R. Goodwin Mumbray.
The Regulation of Prices.
Sir, — As the subject of the present disastrous tendency to
cutting prices below the profit margin is evidently one which
interests most of your readers, I gladly avail myself of the hos¬
pitality of your columns to make a few remarks bearing thereon.
For many years past as managing director of the businesses
Wilcox and Co. and Gabriel Jozeau, I have been receiving com¬
plaints which may be grouped under three heads : (1) From the
public, who purchase the proprietary articles advertised by us,
complaining of the reluctance of the retailer to supply the par¬
ticular article demanded, and of his persistent endeavours to palm
off something else in lieu thereof. These complaints for the most
part have reference to demands for Mariani Wine ; (2) from whole¬
sale dealers in proprietary medicines, complaining of other
dealers selling the goods at an invisible profit ; and (3) from
retail chemists complaining of their inability to obtain
a working profit on the sale of our proprietary articles, on
account of the prices having been ‘ ‘ cut ” so low as to leave no
margin for a “living wage!” Now it may safely be asserted,
speaking generally, that the demand for this class of goods is
created by advertisements. The handling of these goods com¬
paratively requires little skill, and entails a minimum of working
expenses, but it is evident that the distribution should secure a
fair margin of profit on their sale, otherwise it cannot possibly be
worth one’s while to sell them.
With regard to the first group of complaints it may fairly be
asked whether the public really object to paying a price which
shall allow of a reasonable margin of remuneration for work done.
Would not the public generally prefer to obtain what they
require promptly and certainly without having to resist the
insidious arguments of the salesman, seeking to foist upon
them some “superior” article instead of the one asked for?
Passing on to the second group, it must be conceded that the
keen competition which has manifested itself in this department
of trade for some years past, has had for result that the wholesale
dealei’s work very hard for very little pay. This fact suggests the
question whether it would not be vastly to their advantage for all
of them to sell these proprietaries at the same price. There is na
danger of their seeking to exact an exorbitant profit, for any such
policy would promptly be met by a combination of retailers
buying goods in wholesale quantities and dividing them up.
Lastly in respect of the third group, would not the business of
the retailers be placed on a much more satisfactory basis, if they
agreed between themselves, or with the proprietors, to establish
fixed minimum prices for all proprietary articles, comprising a
Jan. 23, 1897]
PHARMACEUTICAL JOURNAL.
79
reasonable profit on the sale thereof ? The public would gain by
the adoption of such a scheme, inasmuch as they would then be
enabled to obtain what they wanted at the nearest shop, instead,
as frequently happens, having to take a cab, or wasting valuable
time in order to obtain a possible reduction of price elsewhere.
Hitherto I have taken the view that purchasers of my goods
were quite at liberty to deal with them when bought as thought
best, and it always appeared to me to savour of impertinence to
dictate or even suggest the price at which they should be retailed,
beyond, of course, advertising the retail prices at which we our¬
selves sell the articles in question. Even now, I feel very strongly
that boycotting and contracts restricting the freedom of trade are,
in many respects, open to objection. The conclusion has, however,
been forced upon me, that this extreme ‘ ‘ cutting ” must, in the
long run, diminish the value of the proprietary articles in which I
am personally interested. This is so obvious that, in self-defence,
I feel justified, when selling goods, in fixing a minimum sale price
in respect of the wholesale and retail dealers, leaving it to them
to fix the price, above the irreducible minimum at which they will
dispose of them. I am well aware of the difficulties which such a
course presents in carrying out, and I have, therefore placed
Mariani Wine and Santal Midy upon the P.A.T.A. list. These
minimum prices I have fixed from a public point of view, and to
the best of my thirty-five years’ experience in wholesale and retail
as follows : —
Mai’iani Wine, advertised 45s. dozen, or 4s. bottle, minimum selling
prices 40s. per dozen, 20s. per half dozen, or 3s. 6 d. per bottle.
Minimum trade price 35s. per dozen or part of dozen. In cases of
six dozen, £10 4s. net, and in six-case lots, 3 per cent, discount.
Santal Midy, minimum cutting price 3s. 6 d. per bottle, and
minimum trade price 33s. per dozen or part of dozen. Per twelve
-dozen £18 net.
I may point out, in conclusion, that my advertisements bring
■customers to chemists, who will not improbably prove to be pur¬
chasers for other articles in addition to those advertised by us.
All I ask is, that my goods shall be supplied when asked for, and
I hope most sincerely that my customers will recognise that it is
also to their advantage to conform to the stipulated conditions in
respect of the minimum prices.
London, January 16, 1897. J. John Snook.
Sir, — I am in favour of the P.A.T.A. because I do not wish to
charge more than my neighbours for “patents,” and I do not
wish to sell these without a working profit. I should like to see
the demand for pills, syrups, compressed drugs, etc., supplied by
those who are, or ought to be, best qualified to supply them, the
chemists. What is wanted is one of ourselves to organise the
forces so that an association of chemists might be formed to set
a-going a pill, an ointment, an embrocation, a syrup, etc., etc.
We could do this and have our 25 to 50 per cent. , while the public
—our customers — would be no worse, perhaps better. We need a
Glyn- J ones to do for the chemists in this direction what our friend
has done and is doing for them in another.
J anuary 18, 1897. A Pharmaceutical Chemist.
A Disclaimer.
Sir, — It has quite recently come to my ears that certain members
cf the craft have been crediting me with the authorship of the
letters which lately appeared in your columns signed “Natu
Minimus.” I must confess I was not a little struck with the truth¬
fulness and d propos nature of some of the remarks of your wrath¬
ful correspondent, but I entirely disclaim all knowledge of, or
connection with, the writer. If I am ever led to discuss the
subject our anonymous [friend has initiated it will certainly be
over my own name. I ask you to insert this disclaimer solely
with the object of correcting the unfounded rumours that are in
circulation.
Leith, January 12, 1897. George Coull.
Syrup Making without Heat.
Sir,— It is not necessary to send out of the country for special
•apparatus for “making syrups in the cold,” as more than twenty
years ago I made them in an ordinary York glass percolator. My
modus operandi was to tie a bit of flannel over the bottom of the
upper part, add the sugar, and turn percolator off, pour the water
on and allow to macerate for an hour, and then set it going. The
sugar was dissolved and strained as it passed through the flannel,
give a shake, and there you are. In this way I have made syrupus,
syrupus scillie, syr. pruni virg., Parrish’s syrup, etc. The only
trouble was with the blued sugar, as the blue was thrown out and
the syrups made muddy, but recently having tried a special blue¬
less sugar manufactured by Messrs. Macfie and Sons, Liverpool,
specially for syrup making, it left nothing to be desired.
Liverpool, January 16, 1897. James Wood.
Chemists’ Federation.
Sir, — Is it not rather surprising that no greater notice has been
taken of Mr. Foulston’s letter of January 9 in the Pharmaceutical
Journal, in which he raises the flag of federation with, as it were,
a bugle call of “ Wake, Brethren, Wake ” ? It cannot be expected
that the P.A.T.A. will do all that is necessary for the retailer ;
although very good in itself and its aims, its very constitution
prevents that. In this town of Plymouth I know there are several
chemists who would join with others to start a proprietary medi¬
cine on lines to be hereafter decided, probably some article which
could be recommended by doctors and in which doctors might also
take shares, thereby giving it a better start. Will not the “ ever
faithful” city of Exeter join with us, her big sister ; also Bradford,
who so boldly protested against the action of St. Jacob?
Birmingham, too, whose motto is “Forward”; will the chemists
there not do their share and communicate with Mr. Foulston, as
he suggests in his letter, either direct or through the Journal?
This is an opportunity which should not be allowed to pass
unheeded, for by taking action now the seed may be sown at small
expense to each, which will bring in a good harvest of profit by
and by. If the secretaries of local associations would talk the
matter over with their members, and write their opinions to Mr.
Foulston, great good might be done. But individual grumbling is
worse than useless, for it is waste of time. I understand there is
a small amount of money promised, but not anything like enough
to start with. It ought not to be very difficult to raise the £5000
asked for, or £20,000 if needed, when the object is to promote our
own interests.
January 18, 1897. Plymouthian (76/33).
The Journal and the Students’ Page.
Sir, — Whether it be a change of ideal or merely the carrying out
by authority of old ideas matters little ; in any case you are to
be congratulated upon the decided improvements made recently in
the official trade journal, for whilst taking more account of the
commercial and utilitarian matters appertaining to the pharma¬
cist’s calling, you are still not neglecting the more scientific ones.
Whilst we (the subscribers, and, of course, proprietors) must
think more and better of our J ournal than before, I hope to see,
and think we may reasonably look for, still further developments
in the direction indicated. Even now I think every pharmacist
ought to read the Pharmaceutical Journal — whatever else he may
read — and I see no reason why it should not become an “indispens¬
able ” to him in his business, as well as a great educational aid to
the younger members of the trade. ‘ ‘ The Students’ Page ” is a
particularly good idea, and, so far, appears to be carried out on very
common-sense lines. I am pleased to add my congratulations, and
to know that my opinion is endorsed by many of my fellow chemists.
Manchester, January 18, 1897. Harry Kemp.
Sir,— Having been a subscriber for now some eight years, I have
ever found the Pharmaceutical Journal a most valuable and
indispensable companion in my daily work. It brings before us
weekly all the latest information in the rapid and ever increasing
developments in science of which we pharmacists of to-day cannot
well afford to be ignorant of. Its general character from a trade
point of view has of late years been greatly enhanced in giving us
the market reports, and latterly the “ Students’ Page,” which has
been a welcome addition to many of the craft.
January 16, 1897. J. P. K. (76/36).
Sir, — Your “ Students’ Page ” is a very good idea, and will be
appreciated not only by students, but also by those whose student
days are over.
Landport, January 16, 1897. W. L. Barrett.
Sir, — Kindly allow me to express my appreciation of “ The
Students’ Page.” Although I have successfully got over the
“ Minor ” difficulty, this page is very interesting and use¬
ful. May I suggest that articles and hints, etc., suitable for
Major students should be included from time to time? [This sugges¬
tion is already under consideration. — Ed. Ph. J.] I think the
“ Students’ Page ” is a step in the right direction, for thus the
80
PHARMACEUTICAL JOURNAL,
[Jan. 23, 1897
Journal will enlist the support of students and associates not in
business with encouragement for study in their leisure.
January 20, 1897. H. I). K. (77/8).
The P.A.T.A. Meeting at Dumfries.
Sir, — Kindly allow me space to correct one or two remarks
inadvertently made by Mr. Glyn- Jones, at the recent meeting of
the P.A.T.A., in regal’d to no cutting of prices, etc., in Dumfries.
For several years Dumfries has had a branch of one of the principal
cutting houses in Glasgow, as well as several grocers, who issue
price-lists regularly, and stock all the leading patent and pro¬
prietary articles, etc., at lowest store prices. When Mr. Jones
stated that we got Is. or face value for Is. 1 %d. articles, Mr. Daniel
replied that business was not quite in such a happy condition as
was pictured. And to meet the store competition, all the chemists
have reduced their prices more or less for some years. Where we
occupy a fortunate position is, in that in all matters regarding the
business we meet as an Association and act unitedly. We are not
so fortunate as to have abundance of elbow room, for there are
twelve chemists’ shops in Dumfries for a population of 18,000, and
this I think is a good deal above the average in most towns.
Dumfries, Jan. 16, 1897. J. W. Sutherland.
Hon. Sec. Dumfries Chemists’ Association.
Proposed Association at Newcastle-on-Tyne.
Sir, — A meeting of chemists and druggists recently held in this
city passed a resolution in favour of holding a meeting to consider
the advisability of forming an association of chemists and drug¬
gists to deal with scientific, educational, and trade matters, and to
promote social intercourse. The meeting also called upon me, as
local secretary of the Pharmaceutical Society, to convene the
gathering. I have therefore sent out circulars to all whose
addresses I have in Newcastle and Tyneside inviting to a meeting
at the Crown Hotel on Wednesday, the 27th inst. , at 8 p.m. May
I ask you to make this known through your paper, and if I have
inadvertently omitted to send the invitation to anyone interested
I ask him to accept this intimation and come to the meeting ?
11, Grey Street, Newcastle-on-Tyne. T. Maltby Clague.
January 19, 1897.
The Preparation of Boroglyceride.
Sir, — In your issue of last week I notice on page 60, under the
head of “Preparation of Boroglyceride,” you say : “You must not
look on Martindale as an infallible guide, or you may be led
astray.” In the ‘ Extra Pharmacopoeia’ I say boroglyceride is “a
patented preparation, made by heating 92 parts of glycerin with
62 parts of boric acid. A tough, deliquescent mass is produced,”
etc. This I abstracted from the specification of the patent, and in
the light of the details which you publish I do not see anything
incorrect in this note on a patented preparation. I am not
infallible, but I hold that the ‘ Extra Pharmacopoeia ’ is more
nearly free from errors than most works of the kind that have been
published.
London, January 20, 1897. Wm. Martindale.
**'* We much regret to learn that Mr. Martindale feels hurt by the reference to
his book last week, in a reply to a correspondent who complained that the
details given in the ‘ Extra Pharmacopoeia ’ were insufficient to enable him
to produce a satisfactory product. All that it was intended to convey is
what should be a self-evident fact — that no book, however eminent its author
or authors, can be depended upon as an absolute guide upon every subject of
which it treats. It does seem, moreover, that practical works, written or
compiled by pharmacists for pharmacists, should as far as possible give essential
working details, from the writers’ own experience if necessary. — [Ed. Ph. J.]
ANSWERS TO QUERIES.
[Queries addressed to the “ Editorial Department, 17, Bloomsbury Square, W.C.,”
will be replied to in the Journal as early as possible after receipt, but the Editor
cannot undertake to reply to them through the post, noi • is it always possible to publish
answers the same week. Questions on different subjects should be written on separate
slips of paper, each of xoliich should bear the sender's name or initials. Readers
requiring working formula for special preparations, and intimating their wants to the
Editor, will be assisted as far as may be practicable. The word “parts," when used in
formUlce, invariably indicates parts by weight. Anonymous queries will be ignored.]
Dr. Begbie’s Pills. — These are composed of podophyllin, gr. J ;
pulv. ipecac., gr. $ ; ext. tarax., ext. hyoscy., aa gr. 1£. Ft. pil. i.
[Reply to Associate. — 73/29.]
Brown Varnish. — Seed lac, 12 ounces ; dragon’s blood, 1 ounce ;
methylated spirit, 1 pint. Let stand in warm place till dissolved.
[Reply to Country Man. — 74/37. ]
French Polish. — Shellac, 5 ounces ; seed lac, 1 ounce ; sanda-
rach, \ ounce ; mastic, 1 ounce ; methylated spirit, 20 fluid ounces..
Let stand in a warm place in a well-corked bottle, shaking oc¬
casionally until dissolved. [Reply to Country Man. — 74/37.]
White Hard Varnish. — White shellac, 1 ounce ; mastic,
4 ounces ; methylated spirit, 24 fluid ounces ; powdered glass,.
2 ounces. Mix and let stand in a warm place until the resins
are dissolved. The glass acts as a mechanical purifying agent..
[Reply to Country Man. — 74/37.]
Boroglyceride. — The specimen you send appears to be [a
mixture of boric acid and glycerin, prepared without heat. You
can prepare a similar article by mixing boric acid, 40 parts by
weight, with glycerin, 28 parts, and rubbing them together in a
mortar. [Reply to Associate. — 75/9.]
Botanical Works. — Shirley Hibberd’s ‘Field Flowers’ is-
published by Groombridge and Sons, London, at about 3s. 6<Z. ;
Grierson’s ‘ Lessons from Fields and Lanes,’ by Bleasdale and Co.,,
York, at Is.; Holmes’ ‘ Botanical Note Book,’ by Christy and Co.,
London, at 3s.; and Hayward’s ‘ Botanist’s Pocket Book,’ by Geo.
Bell and Sons, London, at 4s. 6 d. [Reply to W. L. B. — 76/26.]
Edison-Lalande Battery. — This and all other electrical
apparatus can be obtained from The General Electric Company,.
Queen Victoria Street, E.C., or The Electrical Accessories Com¬
pany, Ltd., 110, Charing Cross Road, W.C. Full details will be
given later as to wholesale houses. You could use the battery for
a small motor, and the cost would vary from 12s. 6d. to 17s. 6oL
[Reply to J. D. C.— 75/29.]
Digitalis. — It is apparently the intention that the pharmacist
should collect and dry his own digitalis. Even in calcareous and
clayey districts foxglove is easily grown in gardens, if sandy or
gravelly soil is provided for it. The leaves, if collected according
to the directions of the Pharmacopoeia, would be of medium size,
and would not have long or broad leaf stalks, such as the first
year’s leaves have. We are not aware of any difference in the
physical characters of the leaves by which the first and second
year’s growth might be distinguished. [Reply to J. H. — 75/28.]
Mountants for Diatoms. — Storax has been recommended by
several workers. Dr. Piffard’s plan is to liquefy on a water-bath,
filter through two or three thicknesses of cheese-cloth on a hot-
water funnel, and when cold mix with an equal weight of xylol.
Shake at frequent intervals during a fortnight or more, then filter
two or three times through absorbent cotton or Swedish filter-
paper, evaporate to the consistency of treacle, and to each two
parts add three parts of naphthalin monobromide. Finally, heat
gently until a clear amber-coloured fluid is obtained, and if the
best results are desired bring the refractive index of the medium
to 1‘625, by adding more of the ingredient that happens to be
deficient. Liquidambar is, of course, the generic name of the
plant yielding storax. Tolu can probably be prepared for your
purpose by similar treatment to storax. Canada balsam dissolved'
in toluol is also used as a mountant. [Reply to J. A. — 76/30.]
CORRECTION.
Local Secretary for Maidstone. — The new local secretary for
Maidstone is Mr. Alfred Frederick Corfe, and not Mr. A. C. Cobb,
as reported on page 47.
COMMUNICATIONS, LETTERS, etc., have been received from
Messrs. Allan, Andrews, Austen ; Barrett, Bartlett, Bayley,
Bienvenu, Bingley, Birkbeck, Booth, Bolton, Boyd, Bramwell ;
Clague, Clark, Cocks, Coleman, Corfe, Coull, Cowper, Cracknell,.
Crampton, Crick ; Davidson, Davies, Dyson ; Eberlin ; Garvie,
Glass, Glyn- Jones, Goodall, Gunn; Hardie, Hetherington,
Higham, Hill, Hogg, Hoit, Holding; Jolly; Keith, Keif, Kemp,
King ; Lillard, Linstead, Lloyd, Luke ; Mallett, Mander, Martin¬
dale, Miller, Morris, Mumbray ; Nall ; Parker, Pirie ; Raimes,
Reynolds, Russell ; Snook, Squire, Stonham, Sutherland, Symes ;
Warden, Wardleworth, Wild, Wood.
PHARMACEUTICAL JOURNAL.
81
Jan. 30, 1897] X, \
I
"THE month:
<z\
JAM 97 /^!
H/ Kayser points out that with the aid
Spectral Analysis of such measurements of the spectra of
and the elements as are now available it will
Wave-Lengths, be possible to effect trustworthy qualita¬
tive analyses, though the need for such is
likely to occur but rarely, spectral analysis being mostly too deli¬
cate for general chemical uses. It shows everywhere traces of
impurities which are far from distinguishable and of no significance
chemically, but in the determination of the atomic weights of
elements and similar work the chemist ought to ascertain the
purity of his material spectroscopically. By the more accurate
measurement of wave-lengths it has also become possible to
arrange the spectra of certain elements in groups based
on analogy of the spectra, as in the following instances : — 1. Li,
Na, K, Rb, Cs. 2. Cu, A g. 3. Mg, Ca, Sr. 4. Zn, Cd, Hg. 5.
Al, In, Tl. All the lines of any element appear to be arranged in
a series, and the spectra of the alkalies consist of three series of
pairs of lines, one principal and two subordinate series. Those of
Cu and Ag have the same subordinate series of pairs, whilst in the
spectra of Mg, Ca, and Sr the two series consist of triplets of lines.
The same holds good for the spectra of Zn, Cd, and Hg, but the
two series of pairs occur in those of Al, In, and Tl. In each group
the difference of vibrations of the pairs or of the triplets increases
with the atomic weight of the elements, and it is about propor¬
tional to the square of the atomic weight. In each group, again,
with the increasing atomic weight, the spectrum advances con¬
tinually to long wave-lengths, as if the heavy atoms vibrate more
slowly, whilst from group to group there occurs a considerable dis¬
placement of the spectrum towards the ultra-violet. — Cherniker
Zeitung and Chemical News, lxxiv. , 307.
The practical bearing of the foregoing re-
New Law suits has been strikingly exemplified by the
Of work of Runge and Paschen on the gas
Wave-Lengths, evolved from cleveite. On measuring the
spectrum of this gas they found that its lines
could be arranged in six series, of which three display single
lines only, but the other three consist of double lines, and
form a spectrum exactly corresponding to the type of the alkalies,
».€., a principal and two subordinate series. The conclusion drawn
from these experiments by Runge and Paschen is that the cleveite
gas consists of two elements — helium and another as yet unnamed.
The lines of both have long ago been observed in the chromo¬
sphere and in many stars. On the assumption that the lines of an
clement are divided into series, an important new law connecting
the wave-lengths of different lines of the same element has recently
been enunciated by Professor A. Schuster, in the following
terms : — “ If we subtract the frequency of the fundamental
vibration from the convergence frequency of the principal series we
obtain the convergence frequency of the supplementary series.”
This law has been found to hold good for the alkalies and for the
two constituents of cleveite gas, i.e., in the cases for which
Kayser, Runge, and Paschen have established the existence of a
principal and subordinate series.— Chem. Zeit. and Nature, lv., 200.
The apparatus devised by Dr. J. C. Bose
Electric for the study of the properties of electric
Wave waves is founded on Lodge and Branly’s
Apparatus. discovery of the “coherer” for detecting
those waves, and the general design of the
apparatus was originally described by Professor Lodge in his book
on “ The Work of Hertz and Some of his Successors.” By means
Vol. LYIII. (Fourth Series, Yol. IV.). No. 1388.
of the complete apparatus it is possible to conduct experiments on
the verification of the laws of reflexion, the phenomena of refraction,
selective absorption, the phenomena of interference, double refraction
and polarisation. It consists of ( 1 ) a radiating apparatus emitting
electric waves of short length ; (2) a receiver used as a detector of
electric radiations ; and (3) various accessories for the study of the
different phenomena. In view of the sensational misdescriptions
of Dr. Bose’s apparatus and the work it is capable of accomplishing
that have been published, the illustrated description now pub¬
lished is particularly welcome. — Philosophical Magazine, xliii. , 55.
C. E. Walt has shown that neither metallic
Oxidation silver finely sub-divided by mechanical means,
Of nor silver freshly obtained from its chloride by
Silver. the action of zinc, is soluble in acetic acid.
Argentic oxide, however, is soluble in that acid
and can be completely precipitated from the solution by means of
metallic lead upon boiling. Experiments conducted by the same
chemist indicate that minutely sub-divided metallic silver can be
oxidised when heated in the muffle of an assay furnace with man¬
ganese dioxide, but not when heated with iron, bismuth, copper,
or zinc oxide, or with calcium carbonate. The oxygen that com¬
bines appears to be derived from the manganese dioxide only, and
the proportion of silver oxide produced varies inversely with the
duration and amount of heat and the quantity of manganese
dioxide present. The oxides of lead and barium are also capable
of reacting with metallic silver under similar circumstances.
Commenting on the ease with which silver may thus be oxidised
by lead oxide, and particularly by substances such as manganese
dioxide and barium dioxide, which give up part of their oxygen on
gentle ignition, the author asks whether it is not reasonable to
assume that certain losses or irregularities in the treatment of
silver and its compounds may be due to this cause. — Journal of
the American Chemical Society, xviii., No. 3.
The use of calcium carbide as a metal-
Reauetion lurgieal reducing agent is described by H.
by N. Warren. On excess of litharge being
Calcium Carbide, heated to redness with the carbide, metallic
lead and calcium oxide result, the reaction
being accompanied by vivid incandescence. When the carbide is
in excess carbon dioxide is evolved, and a regulus of calcium and
lead obtained, of varying percentage according to the temperature
employed. The alloys thus formed are all more or less brittle and
to a certain extent sonorous when struck. Their melting points
rank below that of pure lead, and they are slowly but completely
decomposed in contact with aqueous vapour, the reaction being
much less energetic than that afforded by alloys of lead with the
alkali metals. Stannic, cupric, and ferric oxides are readily
reduced by the carbide, but yield results of no practical value,
whilst manganese, nickel, cobalt, chromium, molybdenum, and
tungsten oxides yield calcium alloys on reduction. — Chemical
News, lxxv., 2.
This compound, CsHnNC7H802, has been
Piperidine prepared by Dr. Schidrowitz by the action of
Guaiacolate. piperidine on guaiacol dissolved in benzol
or petrolic ether. It orystallises in prismatic
needles or plates, melts at 79°’81 C., is soluble in water
to the extent of 3 ‘5 per cent., and also easily soluble in
most organic solvents. Mineral acids and alkalies decompose
it into its constituents. It has been used in the treatment of
phthisis by Drs. Chaplin and Tunnicliffe, who suggest that its
pharmacology resolves itself into that of guaiacol and piperidine,
as the compound is decomposed into those substances, probably
in the alkaline medium of the duodenum. The solubility of the guaia-
82
PHARMACEUTICAL JOURNAL.
[Jan. 30, 1897
colate is remarkable when contrasted with the insolubility of guaiacol
carbonate. Thus, ten grains canbe administered in an ounce of water
or, if a little glycerin or mucilage be added, as much »as
thirty grains can conveniently be given at once. The evidence
of the therapeutic effect seems much stronger than is usually
forthcoming in the case of new remedies. It also appears
to be perfectly safe up to thirty grains three times a day,
besides causing no unpleasant effects. It is well borne by the
stomach, and patients improve in appetite and general strength
while under its influence. Unfortunately the remedy is a patented
one, but the rights have been secured by English chemists, and
the preparation is being manufactured by Messrs. Joseph Turner
and Co., of Queensferry. — British Medical Journal, No. 1881, p. 136.
By precipitating an aqueous solution of
Mercury mercuric chloride with borax, Tokayer (Pharm.
Pyroborate. Post, xxv., 156) obtained a brownish-red pre¬
cipitate, which he regarded as mercuric pyro¬
borate, HgB407. This substance has recently been successfully
employed as an antiseptic, being applied in the form of a 2 per
cent, ointment, with lanolin as a basis. Dupuoy, however, has
examined this salt and finds that it contains no boric acid what¬
ever, but is a basic oxychloride of mercury, having the formula
HgCl2,3HgO. This oxychloride may be produced by treating a
boiling solution of mercuric chloride with sodium carbonate,
keeping the mercuric salt in excess, however, or other oxychlorides
will be formed. — Bullet, de la Soc. de Pharm. de Bord., xxxvi., 269.
Continuing his researches on the metallic
MePCUPy benzoates, Rebiere finds that this salt, as met
Benzoate. with in commerce is far from pure or constant
in composition. Four samples examined gave
No. 1.
No. 2.
No. 3.
No. 4.
Hg .
52-80
42-6
45-12
c7hso2 .
... 24-80
23-20
58-00
54-75
HC1 .
. . . 16-79
+
+
HNO .
.... +
20-36
traces
The fourth sample was prepared by the author, and closely agrees
with the theoretical figures for Hg (C7H602)2, which requires 45 '25
Hg and 54-75 of the acid. This salt is prepared as follows : — A
known quantity of pure mercuric chloride is precipitated with
soda and washed until free from chloride. From the amount of
mercuric chloride taken the amount of oxide is calculated and
sufficient finely powdered benzoic acid mixed with it to leave a slight
excess of HgO. The mixture, diluted with a little water, is left
for twenty-four hours, and then heated to boiling ; a white amor¬
phous powder results, which, when again heated with a large
volume of boiling water, redissolves, and on cooling crystallises
out in long silky needles, which are drained and dried at the
ordinary temperatures. These crystals have the definite composi¬
tion Hg(C7Hs02)2, is true mercuric benzoate, and not an oxy salt.
— Bull, de la Societie de Pharm. de Bord. , xxxvi. , 280.
Although the basic benzoate of bismuth, BiO
Bismuth (C7HB02), has been made official in the French
Benzoate. Codex, Rebiere finds that the commercial
article varies very greatly in composition. Five
samples from different sources were found to differ in constitution,
giving respectively : —
No. 1. No. 2. No. 3. No. 4. No. 5.
Bi . 36-82 42-73 24’99 31'01 50'62
C7Hb02 . 62-72 45-98 48'40 55'66 29 '04
HNO3 . traces 2-16 4'93 traces 3-26
The author criticises the official process, and substitutes the
following method Freshly precipitated oxide of bismuth,
thoroughly washed, is drained to a pasty consistence. The amount
of anhydrous Bi203 is determined in a portion of the paste, and to
the rest is added the theoretical quantity of finely-powdered
benzoic acid to produce the salt Bi0(C7II502), which contains 60 '25
per cent, of bismuth and 35 -12 per cent, of benzoic acid. The
mixture is diluted with sufficient water to make it fluid, well
mixed, and left in contact for twenty-four hours. The precipitate
is then thrown on a cloth, drained, and dried in the air. — Bxdlet .
de la Soc. de Pharm. de Bord. , xxxvi. , 272.
Clarke and Joslin, two American chemists.
Phosphides obtained a definite compound of platinum and
Of phosphorus, Pt3PB, in 1884, the biphosphide
Platinum. alone having been previously known. On dis¬
solving the Pt3P5 as far as possible in aqua
regia, an insoluble protophosphide, PtP, was left, whilst the por¬
tion dissolved contained the biphosphide, PtP2. A. Granger has
experimented on similar lines, and states that platinum wire or
foil is not attacked by phosphorus below a red heat, but phos¬
phide of platinum, Pt3PB, is then produced. At higher tempera¬
tures the bodies formed are less rich in phosphorus, approaching
the sub-phosphide PtJP in composition, whilst at a white heat.
( rouge blanc) the compound does not contain more than 4 per cent,
of phosphorus. In the case of spongy platinum the reaction takes
place below red heat, the biphosphide PtP2 being then formed.
This compound is not entirely soluble in aqua regia, the part dis¬
solved corresponding to Pt3P5. — Comp, rend., cxxiii., 1284.
This body has been obtained by C. Gussmann,
Vanillin. by boiling vanillo-carbonic acid, 1 part, with
aniline, 2 parts, until the escape of carbon
dioxide ceased. The substituted benzyli dene-aniline formed was
separated from excess of aniline by means of a current of steam,
and the vanillin-aniline finally split up by boiling for a short time
with 50 per cent, sulphuric acid. After separating the vanillin
with ether it was readily obtained in crystals. The same pro¬
cedure is applicable for the production of aceto-vanillin from
acetyl- vanillo-carbonic acid. — Comp, rend., cxxiv., 38.
This base appears to increase in favour as a
Eueaine local anaesthetic, and a preliminary communi-
as an cation on its use in the surgery of the throat,
Ansesthetie. nose, and ear is published by W. J. Horne and
Macleod Yearsley. The results of previous
investigations into the action of eueaine show that it is
analogous to that of cocaine, except that eueaine is less toxic,
slows the pulse, and does not affect the pupils. It does not in¬
fluence the heart in any way, the anaesthesia produced is more
extensive than with cocaine, both as regards time and locality, and
solutions prepared with sterilised water and maintained ah
the room temperature remain always clear, even without the
addition of carbolic or salicylic acid, and never become
flocculent like those of cocaine. Eueaine can also be sterilised
by boiling without undergoing decomposition. The points
dealt with in the present communication are the strength,
of solution required (varying from 2 to 8 per cent. ) ; the rapidity,,
intensity, and extent of the anaesthesia ; the general and local,
action upon the circulatory system ; and the after-effects of
eueaine. — British Medical Journal, No. 1881, p. 134.
The effect which coal-tar colours may exert
Coal-Tar Dyes upon digestive ferments has received attention
and at the hands of H. A. Weber, who has experi-
Digestion. mented upon pepsin and pancreatin with.
selected dyes in common use by confectioners
and others. For the experiments on peptic digestion the colour to
be tested was added to the following mixture : — Hydrochloric acid
solution (0’2 per cent.), 100 C.c. ; pepsin, 0 '020 Gm. ; blood fibrin
preserved in alcohol, 1*0 Gm. The fibrin was washed with water
before use to remove alcohol, and excess of water removed by
pressing between filter paper. The mixture was placed in a test-
Jan. 30, 1897.]
PHARMACEUTICAL JOURNAL.
83
tube and heated on a water-bath at a temperature of 38° to 40°
until the fibrin was as far as possible dissolved. Under these
circumstances oroline or acid yellow was found to exert a marked
injurious effect upon peptic digestion, but no effect was produced
by saffoline (acridine red), magenta, or methyl orange under
similar conditions. The mixture used for the experiments on
pancreatin was as follows : — Water, 100 C.c. ; sodium bicarbonate,
1*5 Gm. ; pancreatin, 0'3 Gm. ; fibrin, 1*0 Gm., and in this case
the action of the ferment was unaffected by oroline yellow. On the
other hand, saffoline, magenta, and methyl orange completely
stopped the action of pancreatin in strong solutions and retarded
it to a marked extent in weaker ones. — Journal of the American
Chemical Society, xviii., 1092.
W. B. Thompson refers to the great variety
Blaud Pill. found to exist in the composition of Blaud pills,
and observes that in the numerous essays which
have appeared on the subject, are many finely wrought theories
respecting the action of the supposed free hydrochloric acid and
other normal fluids of the stomach. The acid is “fancifully
conceived ” to be in waiting in that wondrous receptacle ready
to seize first upon any congenial substance which may be ingested —
with a predilection for a ferrous salt of iron — and it is assumed
that an insignificant amount of ferric oxide will prove but a
slight obstacle to the action of this solvent acid. He
suggests, however, that it would appear more reasonable
to cease indulging in any more theories as to the precise
behaviour of the intestinal processes towards foreign substances,
or to speculate upon a probably uniform action regulating animal
chemistry, and rather see that the state of combination is exactly
such as will meet the indications suggesting its use. It will also
be well to know, if the pill is prepared in advance of requirement,
what chemical change or alteration can occur without affecting its
nature as a Blaud pill, as well as the precise character of this pill
as commonly found in commerce, and wherein it differs from the
extemporaneous preparation. — Am. Joum. ofPharm., lxix., 17.
C. H. La Wall considers that the extent to
Adulterated which the Japan wax of commerce is adul-
Japan terated at the present time has never been
Wax. equalled. Of fifty-nine cases containing from
205 to 225 pounds each, twenty-five were
found to be adulterated with starchy material to the extent of
20 to 25 per cent. The specific gravity of the sophisticated pro¬
duct was slightly higher than that of the genuine wax, and it was,
as a rule, free from the peculiar network of minute cracks which
usually characterise the surface of cakes of pure Japan wax. —
American Journal of Pharmacy, lxix., 18.
At the Netherlands Yeast and Spirit Com-
Manufaeture pany’s works in Delft, which yield nearly 100
Of tons of yeast per week, the first step towards
Yeast. the manufacture of that article is the con¬
version of barley, rye, and Indian corn into
malt. After malting and drying in kilns, the malt is macerated in
large wooden tubs and then introduced into the fermentation tubs,
together with a fermenting agent previously prepared by mixing
yeast and flour. After fermentation the yeast appears in a frothy
state on the top of the liquid, and is conducted through channels
into a common reservoir, then passed through sieves to effect
cleansing. It is next collected in a milky state, and after
repeated washings in clean water, transported to filter presses
which remove excess of moisture, leaving a solid cake— the yeast
of commerce. The spirituous liquor formed as a by-product
during the fermentation process, after being drawn off and rectified,
is bottled and sold as Hollands gin. — Engineer.
L. E. Sayre finds that the gelsemium of the
Gelsemium. market is composed of the rhizome, root and
stem in varying proportions, and gives the
results of a microscopical examination of sections of the three
parts. In the stem are found comparatively large bundles of
bast near the wood, just outside the cambium, whereas in the
rhizome the bast is arranged near the corky layer, and in an
interrupted ring rather than in bundles. In the root the bast is
entirely absent, but there are several layers of cork. The following
description is suggested for the official rhizome and root : — Rhizome,
cylindrical, cut or long in sections, mostly 5 to 15 millimetres,
and occasionally 3 centimetres thick ; externally light yellowish -
brown, with purplish-brown longitudinal lines ; tough and woody,
fracture splintery, bark thin, with silky bast fibres near the pale-
yellowish porous wood, which has fine medullary rays, and a small
pith which, under the lens, is seen to be usually divided into four
segments. The root is 2 to 10 millimetres thick ; externally
lighter than the rhizome, fracture brittle, thick bark closely
adhering to the light -yellowish wood, odour of both rhizome and
root aromatic, taste bitter. — Am. Joum. of Pharm., lxix., 8.
According to Dr. B. Lidforss, plants whose
Winter- leaves remain green through the winter, whether
Gre en woody or herbaceous, are characterised by the
Plants. entire absence of starch from the guard-cells of
their stomates during the cold season. By
December it has usually entirely disappeared ; but its re-formation
is at once induced by a higher temperature. The same is the case
with the starch in the mesophyll of the leaves. The cells of the
mesophyll contain, on the other hand, large quantities of a soluble
carbohydrate, probably glucose. The transformation of starch into,
glucose probably acts as a protection against cold in the same way
as the formation of oil in evergreen trees. Submerged plants — -
mosses and green algae — exhibit similar phenomena. — Botanisches-
Centralblatt , vol. 68, 1896, p. 33.
From a series of observations made chiefly
Homology of on abnormal structures of Torilis Anthriscus.
the Pollen and Sinapis arvensis, M. M. Molliard has come
and Ovule. to the conclusion that the anther corresponds.
homologically to a simple leaf, the limb of
which is folded over on each side of the median vein. Each half
gives rise to a mass of pollen ; but the two halves are not of equal
value, one contains the median fibrovascular bundle, while the
other one is an emergence of the first, and contains only very small
vascular bundles. From the study of a number of cases of transforma¬
tion of stamens into carpels in Sedum, Petunia, Narcissus, etc., he
concludes that the entire pollen mass of an anther is the homo-
logue of a row of ovules, the integument of the ovule corresponding
to the invaginated epiderm. The degree of coalescence between
the nucellus and the integument varies greatly in different classes
of plants. The naked ovule of the Santalacese and Balano-
phoracefe corresponds altogether to a pollen mass. The number
of rows of ovules in a carpel varies in proportion to the number of
pollen masses in each anther-lobe. The non-marginal placentation
of Papaver and Nymphcea may be compared to the distribution of
the pollen masses over the whole upper surface of the staminal
leaf in Viscum. — Bonnier' s Rev. Gin. de Botanique, vol. viii. , 1896.
Mr. F. W. Keeble records some very
Fertilisation interesting facts respecting the Cingalese
and species of Loranthacese. All those which
Germination of have tubular flowers are ornithophilous>
Loranthaeese. the bird which usually effects the pollination
being a honey-sucker. In many speciea
the corolla is split longitudinally, and the anthers are then placed
84
PHARMACEUTICAL JOURNAL.
[Jan. 30, 1897
in a row behind the style, instead of in a ring around it ; and this
greatly facilitates the carriage of the pollen by birds in search of
the nectar. In some of the large-flowered species the flower-buds
remain closed ; but when tapped, as by the beak of a bird, the
corolla lobes fly open with an explosion, and the pollen is scattered.
The closing of the buds appears to serve the purpose of protecting the
pollen against rain ; while the violent expulsion of the pollen aids in
its carriage by the visiting birds, their beaks being frequently found
to be covered with pollen after visiting the flowers. Mr. Keeble
doubts the correctness of the common statement that the seeds of
the Loranthacese [e.g., the mistletoe) pass through the bodies of birds
without injury, and are voided with the excrements. As far as
the Cingalese species are concerned, birds eat the succulent
portion of the fruit only, wiping out the seeds with their beaks on
to the branch of a tree ; or, if swallowed, they are frequently
digested and destroyed. In some species the sucker by which the
seedling is attached to the branch puts out one or more aerial
roots which reach other branches, or even the soil, and enable the
young plant to carry on a semi-parasitic life. The hypocotyl ex¬
hibits negative heliotropism, but no geotropism. It curves away
from inert bodies and even from its natural host when the
conditions are not favourable for growth. — Trans. Linn. Soc.,
Botany, vol. v., part 3, 1896.
In an article on the philosophy of species-
Philosophy making, L. H. Bailey discusses the species-
Of conception, the art of species-making, and the
Speeies Making, hybridity corollary. He defines a species as
“ The unit in classification, designating an
assemblage of organisms which, in the judgment of any writer, is
so marked and so homogeneous that it can be conveniently spoken
of as one thing.” It is not made a test of a species that there
should be no intergradient forms. If the intermediate forms are
so few that they do not seriously obscure the mental conception
of the type, then all interests will be subserved by disregarding
them for purposes of nomenclature. Very few species of plants
can be expected to be perfectly free from aberrant and entangling
forms, and the groups are rare in which it can be said that the
types are unique, for soil, exposure, climate, contest with fellows,
and a hundred incidental circumstances leave their impress upon
the plant forms. It is suggested that if the making of species is
an expediency, it is neither necessary nor desirable to search for
obscure or anatomical characters with which to separate them,
and that the species-division will be useful in proportion as it
is founded upon obvious and easily -ascertained attributes.—
Botanical Gazette, xxii., 454.
An interesting discovery has been made by
Prehistoric E. Piette, in a cave at Mas-d’Azil, on the left
Human bank of the Arise, in the Department of
Relics. Ariege, a layer of pebbles having been excavated
there which bear various devices painted
with peroxide of iron. The marks appear to represent minerals,
crosses, and other symbols ; pictographic signs apparently
representing snakes, trees, etc., and alphabetical characters.
These pebbles are supposed by the discoverer to date back
to the later Quaternary Period, during the Asylian phase,
at which time it is suggested man had forgotten the arts of
engraving and carving on reindeer bones, etc. , and had commenced
to devote himself to cultivation and painting quaint forms on
rolled stones. M. Piette states that “thirteen out of twenty-
three Phoenician characters were equally Asylian graphic signs,”
and it is difficvdt to conceive that the devices, as illustrated by
the author, are either meaningless cabalistic signs or aimless
decorations. — Anthrapologie, vii., 385, and Nature, lv., 229.
OUR WEIGHTS AND MEASURES.*
At a time when a radical change in the standard weights and
measures employed throughout the British Empire seems not
altogether impossible, though likely to be preceded by a more or
less prolonged period during which old and newer systems will be
used side by side, it is interesting to stop to consider how we stand
in the matter and what the standards are that it is proposed to
relinquish sooner or later. But accurate and recent information
on the subject has been difficult to obtain, on account of the
manner in which it was scattered in official reports, papers, etc. ,
and the connected account now furnished by the Superintendent
of the Standards Department of the Board of Trade is, therefore, a
welcome contribution to the literature of the subject. He describes
the work as an attempt to indicate what is now the practice in the
use of our various weights and measures, either in trade or for the
purposes of manufacture, and as an attempt it must be regarded
as remarkably successful.
Commencing with a consideration of the origin of the Imperial
system, the author shows that it is based on two units, the yard
measure being the unit of length, and the pound weight that of
mass, the standards in each case being deposited at the Standards
Office, Old Palace Yard, Westminster. The term “Imperial”
was first used in reference to our weights and measures in a report
of the Weights and Measures Commissioners, published in 1821,
but the legal introduction of the Imperial system dates from 1824,
when an Act of Parliament was passed with the object of removing
the existing diversity in usage and so preventing great confusion
and manifest fraud. Attempts in this direction had repeatedly
been made from the time of Henry III. , but custom has proved so
strong with the people of these islands that even yet absolute
uniformity does not exist. The first Imperial standards were
injured or destroyed at the burning of the Houses of Parliament
in 1834, their legal life being thus exceedingly brief as compared
with that of the old Winchester standards, which lasted from
1588 to 1824. New standards were not legalised until 1855, wheu
the avoirdupois pound of 7000 grains was substituted for the Troy
pound of 5760 grains, and from investigations made at that time
there appears little doubt that the present Imperial standards
have been accurately derived from those of Queen Elizabeth, the
latter in turn having been derived from those of Henry VIII. Copies
of the new standards were deposited in the Houses of Parliament, at
the Royal Observatory, in the Royal Mint, and with the Royal
Society. In the event of the original standards being lost or injured,
new ones can, under the Weights and Measures Act, 1878, be
created by reference to or adoption of those “Parliamentary Copies.’
Descriptions of the present Imperial standards are followed by
detailed references to ancient standards, the local or subsidiary
standards by which the trade weights and measures are controlled,
and the probable origin of our ancient systems. Fiction and fact
alike receive attention, but the author is content to trace the origin
of our measures of length back to Roman and Anglo-Saxon times.
The old London mile (5000 feet of 1000 paces) was in all probability
derived from the Romans, and the yard from the Anglo-Saxons,
who doubtless brought their own weights and measures from
Germany. But Greece and Arabia also contributed their quota to
the foundation of the existing system, whilst various Eastern
countries have had attention directed to their claims in this
matter. In all cases the original standards were almost certainly
devised from natural constants, but faith is no longer pinned
* ‘ Our Weights and Measures’ : a practical treatise on the standard
weights and measures in use in the British Empire, with some account
of the metric system, by H. J. Chaney. Pp. 163. Price 7s. 6d.
London : Eyre and Spottiswoode, East Harding Street, Fleet Street,
W.C. 1897.
Jan. 30, 1897J
PHARMACEUTICAL JOURNAL
85
to the accuracy of methods of reference to such constants,
preference being given to material or arbitrary standards
constructed by hand. Thus the yard measure is no longer
required as formerly, to be restored if lost by reference to the length
of a pendulum vibrating seconds of mean time in the latitude of
London, in a vacuum at the level of the sea, nor the pound to be
restored by reference to the weight of a cubic inch of distilled
water at the temperature of 62° Fahrenheit. Neither is the
theoretical metre any longer regarded as the one ten-millionth part
of the elliptic quadrant of the meridian passing through Paris, nor
the kilogramme as the weight of distilled water contained in a
cubic decimetre. They are now simply the length marked on a
metal bar known as the “Metre-International,” and the mass
represented by an iridio-platinum weight known as the “ Kilo¬
gramme-International,” just as the Imperial yard is the length
between two points on a bronze or gun-metal bar at 62° Fahren¬
heit, and the Imperial pound is the weight of a platinum cylinder.
It is worthy of note, by the way, that the metre has been found
to contain 1,553, 163‘5 wave-lengths of the red ray of the spectrum
of cadmium, measured in air at 15° C., and under an atmospheric
pressure of 760 Mm., and that the actual length of the metre bar
at Paris can thus be determined to within a micron.
The old standards used in Scotland, Ireland, the Channel
Islands, and the Isle of Man next receive attention, numerous
interesting facts being classified in this connection, and special
reference is then made to the standards of the United States, whose
history is so intimately connected with that of our own. Sections
on the standards of India, Canada, Australia conclude the first part
of the book. Part two deals with the inspection and verification
of weights and measures used in trade, which should be found
especially useful by manufacturers, traders, local inspectors, and
others interested in their use. Part three is devoted to measures
used for surveying purposes or for the measurement of land, and
part four treats of scientific measuring instruments, including
hydrometers, gas-measuring standards, photometers, and so forth.
The metric system is concisely yet comprehensively dealt with
in part five, descriptions of the standards being succeeded by
tables of equivalents of metric weights and measures in terms of
the Imperial system and vice versd, an account of the origin of
the metric system, and remarks on the proper way in which
weights and measures may be taught in schools. The last
part of the book is descriptive of weights and measures used for
special purposes, commencing with those employed by pharmacists.
As is well known, when sold by retail, drugs may be sold by
apothecaries’ weight, which perpetuates the old Troy pound of
5760 grains, and the wish may be expressed that this part of the
work might have been dealt with much more fully, little being re¬
lated of apothecaries’ weights and measures except that they
appear to have had a Grecian and Arabic origin. Lists of the
weights of the various denominations of coins are followed by an
interesting account of the Pyx Chapel and the trial of the coinage,
as well as the Jewel Tower at Westminster, and part six concludes
with a mass of details referring to the large number of other
weights, measures, and gauges used for special purposes. Then
comes an appendix embodying a list of Board of Trade standards
of the Imperial system, and another enumerating representative
forms of weighing instruments used in trade.
It will be gathered from what has been said that the work may
be regarded as a standard of standards. It only remains to say that
the author’s position in the Standards Department has enabled him
to derive the information given from authentic sources, and the book
is written in a style that leaves little to be desired. -So attrac¬
tively is the matter presented that the general reader may be in¬
terested in it no less than chemists, physicists, and antiquarians,
or those on whose behalf the compilation has been more especially
prepared. The illustration of the book by fine collotypes, litho¬
graphs, woodcuts, and other blocks is most profuse, whilst the
type is excellent, so that in every possible way utility is supple¬
mented by first-class workmanship. Mr. Chaney is therefore to be
most cordially congratulated upon the production of a volume that
is as creditable to everyone concerned as it has long been necessary.
Higher praise than this could not be given.
BACTERIA AND DISEASE.*
BY PROFESSOR E. SYMES THOMPSON, M.D., F.R.C.P.
Minute Organisms as Causes of Disease.
The science of bacteriology at first made slow progress, but
during the last few years it has made marvellous strides, the
steps taken of late being so great that it is impossible to keep up
with the progress of the science unless the whole attention is
given to it, and even then the subject is so vast that „the attention
should be given to one branch alone. In pursuance of the science
of bacteriology, the process of staining microscopical objects
has been of immense service, as by this means it has become
possible to distinguish many minute organisms which otherwise
are not distinguishable. It was discovered early in the history
of the science that ’old buildings became impregnated with
micro-organisms, which rendered old laboratories useless for experi¬
ments which were successful in new ones. This discovery led the
imaginative minds of one or two speculative experimenters to
conceive the idea that diseases were due to a kind of fermentation.
This idea was investigated, and it was found that if microbes
like those found in the air and in old buildings alighted on a
wound they caused suppuration and greatly retarded the healing
of the wound. If these organisms were kept away, suppuration
never occurred. On this account it was found to be necessary to
destroy many of the older hospitals. The microbes, however, fulfil
a purpose of great value by changing dead material from some¬
thing dangerous to something useful, cleansing and destroying and
protecting the living from the dead.
These organisms are of the greatest possible importance not only
in connection with diseases, but with all the processes of life ;
therefore the surgeon must know a great deal about antiseptics
and the best kind to be used in different cases. Antiseptics are of
great value in destroying the microbes of disease, a one per cent,
solution of carbolic acid being sufficient to kill the anthrax bacillus
in two minutes, and a five per cent, solution clearing the bilge
water in a ship in forty-eight hours. The bacillus spores, how¬
ever, have the power of remaining latent after the death of the
bacillus, but a five per cent, solution of carbolic: acid arrests their
growth in four days. A knowledge of the natural history of these
microbes is of the greatest importance to the surgeon and physician
in the checking of human diseases. Pasteur by his observations
and investigations into the diseases of silkworms and vines
discovered the cause to be these micro-organisms, and by destroy¬
ing their power he was enabled to check the disease. The bite of the
mosquito is believed by some people to cause ague, and in like
manner the tsetse fly is said to cause certain diseases which have
interfered with the British troops at Buluwayo, but there is no
harm in the insects themselves, they being simply the means of
conveying the microbes from infected bodies. The rinderpest in
South Africa is largely due to like agencies. Dr. Edington, who
is investigating the matter, claims to have discovered the rinder¬
pest microbe, and is of opinion that a serum of greater or less
virulence can be obtained according to the animal infected, the
disease being less malignant in the aritelope than in cattle.
The bacillus of influenza has recently been discovered, it is very
agile, and has caused investigators a great amount of trouble
before allowing itself to be found. The microbe of tetanus, or
lockjaw, has also been discovered, and it is found that damp, dirty
leather is a very suitable medium for its growth, thus explaining
why horses are so frequently troubled with tetanus, the bacillus
flourishing more readily on dirty harness than elsewhere.
# Notes of lectures delivered at Gresham College, January 19 to 22.
86
PHARMACEUTICAL JOURNAL.
[Jan. 30, 1897
Bacteria in Air and in Water.
Organisms that do not produce spores are easily killed by drying,
and are rarely conveyed by the air. Spores, however, are readily
carried about alone or adhering to dust. There are a certain set
which require air for their activity, and another set which live
without air. These micro-organisms play an important part in
the preparation of food. Bread and beer are prepared from barm
or yeast, which is produced by these organisms. In the manufac¬
ture of butter and cheese bacteria are essential. If butter is
prepared from fresh cream it is insipid and will not keep
well, but if by the help of microbes the cream is allowed
to get sour, the butter will keep much better. The process of
souring is due to the presence of various bacteria. One has the
effect of souring the milk and another imparts its keeping qualities.
Thus in large scientific dairies the milk is first sterilised, and then
is subjected to two kinds of bacilli, which are carefully cultivated
so as to be free from all impurities. The work of preparing the
bacilli is of so important a character that in the majority of the
great dairies and factories in Germany special chemists are
employed for the purpose. In England chemists are also employed
for this work, but many of them are German chemists.
Laboratories are now specially set apart for the work of bacterio¬
logical investigators. The various kinds of bacillus are cultivated
and carefully watched to see how they behave under different
circumstances. It is found that in the pure culture of tubercle
bacilli the growth is very slow, it taking many weeks to
fully develop, and the presence of any other bacillus will
absorb all the nutriment necessary for its growth, thereby
destroying it. Experiments based upon this theory produced
excellent results in the laboratory, but when Dr. Koch en¬
deavoured to turn it to practical use it was found not to work
•quite so successfully. One of the results of a more
accurate knowledge of the minute organisms which abound in the
air and water is a better sewage system. As the forms in the air
become better known it is possible that such terrible scourges to
•humanity as cholera, typhoid, diphtheria, etc., will lessen from
year to year.
Milk, Meat and Oysters as Carriers of Disease.
If it is desired to know how the typhoid organism behaves
within the body, it is essential to watch its growth and develop¬
ment outside the body, and this has been done with great pain and
care during the last few years. The typhoid organism grows best
in the presence of oxygen, but it also grows where air is excluded,
it is both aerobic and anaerobic. If subjected to a heat of 140°
Fahren. it is killed in twenty minutes, but subjected to a freezing
(temperature its vitality is not hurt, and may be kept alive for a
very long time. On sterilised linen it is found to be active after a
period of seventy-one days. Street scrapings have also been known
to contain active typhoid bacillus at the end of thirty days. Car¬
bolic acid and corrosive sublimate destroy the vitality of the typhoid
■organism, and it is rapidly killed in sunlight, the chemical rays of
the sun being most destructive. The germs also seem to have a
particular dislike to the violet rays of the spectrum. In river and
well water it is found that they remain active from forty to eighty
•days, disappearing most quickly from well water, but at the
bottom they remain in a state of activity for a much longer time.
Mud affords a very suitable medium for the germs, the cholera
vibrio retaining in mud its active influence for three months.
Cholera organisms introduced into oysters and then placed
in sea-water have been found to retain their vitality for
eighteen days, whereas typhoid organisms so placed retained their
activity for a period of three months. Thus it is very necessary
that oyster beds contaminated with typhoid should be under
oareful control, so as to arrest the spread of that and many other
diseases.
Milk is also a medium in which bacteria develop rapidly, and
has frequently been the cause of spreading a typhoid epidemic,
but the better-class dairies are now supervised with such care that
the public are almost free from the dangers of an epidemic caused
by contaminated milk. Although a person may take an amount
of virulent poison which is insufficient to produce typhoid fever, it
is possible to take enough to damage the health in other ways. It
is necessary first to set up some irritative action, and to reduce the
vitality of the body before the poison will take effect, and while it
is true a person may be in such a state of vitality as to resist these
organisms, it must not be forgotten that they are the means of
reducing the vitality, so that by again and again introducing these
microbes the body is rendered liable to typhoid and cholera.
It has often been thought that if the presence of typhoid in a
person could be discovered before the symptoms developed, it
would be possible to prevent the disease, and from recent experi¬
ments it seems probable that such a discovery has been made.
If milk or flesh meat is contaminated, in the case of milk
once boiling is sufficient to kill the microbes, but in the case of meat,
as a knife may convey the contamination to the centre of a joint,
it requires to be well and thoroughly cooked to kill the microbes.
In England typhoid fever is found conveyed in milk, water, and
other fluids, but in South Africa and very dry lands the typhoid
organisms fall upon the earth, and are carried about by the
winds and deposited on the house-tops, so that when a shower of
rain comes it carries the contamination into the cisterns, and the
water being warm the microbes speedily develop. The right course
to adopt under these conditions is to run the water off and scour
out the cistern after the first fall of rain ; the water collected
afterwards will then be free from the dangerous organisms. The
germs found in the bodies of those who die of typhoid fever
are rarely found in the blood, but they remain in association with
the tissues, where they live bottled up for many years. It is not
necessary to be afraid of these germs, but rather to take means to
develop the phagocytes, and by living a rational life go through
the world regardless that these microbes exist.
Diphtheria.
The diphtheria bacillus is peculiarly dangerous to doctors and
nurses. It is very infective, and requires great care in exposing
the persons of those whose duty it is to attend on anyone suffering
from the disease, and it is well to disinfect very vigorously when
in contact with it. Diphtheria is found to keep in gelatin as long
as eighteen months, and will lie latent for a much longer time.
The disease is specially prone to attack children, but does not often
affect babies. It attacks girls more than boys, those who are weak
being particularly prone to it. The large tonsil with its little
follicles seems to hold the disease, but the bacteria are not found
very deeply in the mucous membrane ; it is in the false
membrane that the bacillus takes up its abode. During an
epidemic season the bacilli are often found on healthy throats,
so that a perfectly healthy person may find after visfting a
diseased person that he has microbes on his throat. It is possible,
however, to have the bacilli without having diphtheria, and to have
diphtheroid disease without having the bacilli. Immunity
from the disease may be secured by the injection of anti¬
toxin. The mortality caused by diphtheria varies. Some¬
times it is so severe that 50 per cent, die from it.
If the blood of immuned animals is employed, it is found
to give relief in twelve hours, and in an acute stage in twenty-
four hours. Diphtheria antitoxin has been one of the most
important discoveries of the nineteenth century, the results being
very gratifying, inasmuch as the average mortality has been
reduced from 41 per cent, to 15 per cent.
Extract of Chelidonium Majus in Cancerous Tumours. —
Denisenko has employed the extract of greater celandine with
remarkable success in the treatment of cancroid growths. He
ives internally from 1 ’5 up to 5 grammes daily of the extract,
issolved in water or peppermint water ; at the same time he in¬
jects into the tumour, at the limit of the neoplastic and healthy
tissues, a mixture of equal parts of the same extract, of glycerin,
and of distilled water. About a cubic centimetre is employed
each time, distributed into several punctures. Lastly the surface
of the neoplasm where it is ulcerated is painted twice daily with a
liquid composed of one or 2 parts of the extract and 1 part of
glycerin. The internal use of the extract is generally well borne,
and the local applications only occasion a passing smarting. The
injections, however, besides a smarting sensation, occasion a sensa¬
tion of weakness, shivering, and a rise in temperature to 38° or
39° C. These phenomena commence in fifteen to thirty minutes
after the injection, and disappear by the next day. These injections
therefore require to be cautiously given and regulated according
to the susceptibility of the patient. According to the author, the
therapeutic action of the treatment is manifest in a few days. In
three or five days fistulas appear in region of the punctures, around
which the tumour rapidly disintegrates. In fifteen to twenty-five
days a line of demarcation appears between the neoplasm and the
healthy tissues, the volume of the tumour diminishes to one half,
and the swelling of the neighbouring lymphatic ganglia disappears.
— Bull. Com. , xxiv. , 426, after Semaine M ed.
Jan. 30, 1897.]
PHARMACEUTICAL JOURNAL
87
OLD PHARMACY.*
BY FRANK CASSON.
For the earliest mention of drugs and their uses, I think we must
refer to the Bible, remembering, however, that the names of many
drugs have been translated by the nearest English words the
translators could hit upon — in many case3, very misleading. Another
point to be noticed is that the names of drugs, etc., are almost
always introduced indirectly. Physicians and apothecaries, drugs,
and perfumes we read of, Solomon’s plant lore we are told of, but
in very few cases are we told the nature of the remedies employed
against diseases, or anything of the healing art in general. Two
exceptions may be pointed cut — Hezekiah, treated with a poultice
of figs, and the Good Samaritan’s First Aid.
Poisons are mentioned, but only in connection with animals, as
the serpent. There is no mention of preparations of poisons being
used to destroy life. “Witchcraft” (pharmakeia), as used by St.
Paul, may probably mean “ poisoning or else the preparation of
philtres,” etc. In Exodus we have the prescription in a proper
workable form for the preparation of the anointing oil.
Altogether we have mentioned, direct or indirect, forty-five sub¬
stances, including the following : —
Antimony Sulphide.
Camphire.
Colocynth (“ Wild Vines” of II. Kings).
Aloe, “ Lign Aloe,” or Eaglewood, of India, highly prized new as
a perfume.
Natron, or Nitre, probably an alkaline c?.rbonate, mentioned in
connection with soap.
Ricinus probably is meant by “ Gourd ” in Jonah.
Saffron, Vermilion, etc.
Ointments are frequently mentioned, and were largely used as
perfumes ; in Job we have an allusion to their mode of manufacture,
and in Ecclesiastes to the trouble arising from flies in them. Next,
to turn to ancient history On Egyptian sculpture we can find
figures of men using mortar and pestles. Two men are employed,
each with a pestle, striking alternately, while others are sifting and
bringing up fresh supplies. Scales are shown much like our dis¬
pensing scales.
In Greek mythology we read of Aesculapius, son of Apollo, who
studied the art of healing with herbs, and went as ship’s doctor
with the Argonauts on their famous voyage.
The Greeks and Romans had a fair knowledge of soap, starch,
glass, leather, mineral and vegetable pigments, wine, beer, vinegar,
sulphur, carbonate of soda, etc. Hippocrates, who died about b c.
360, and Galen, who died about a.d. 190, are well-known names.
But it is to the Arabs that we owe the greater part of our present
chemical knowledge. They appear to have first tried making new
medicines by chemical changes. As early as the eighth century, A D.,
we find Geber acquainted with or preparing vinegar, nitric acid,
milk of sulphur, arsenic, borax, salt, alum, sal ammoniac, ferrous
sulphate, nitre, mercuric, chloride, and others. His plans for dis¬
tilling apparatus, furnaces, etc., were used for hundreds of years.
From about the ninth to the twelfth century the Arabs were the
great doctors of the world, the Moors being especially famous. The
work was afterwards carried on by the great medical school at
Salerno. During the thiiteenth, fourteenth, and fifteenth centuries,
dispensaries appear to have been founded often at the public ex¬
pense in France and Germany, and we find the first Pharmacopoeia
published at Nuremburg by Cordus in 1542. The first London
Pharmacopoeia appeared in 1618 with eleven later additions. In
the early editions we find the usual animal abominations then in
* Read before the Midland Chemists’ Assistants’ Association.
use — earthworms, frogs, puppies, foxes, skull of man, etc., and
electuaries containing fifty or sixty ingredients, and, in one case
124 different substances.
In this country, so late as the beginning of the sixteenth century,
physicians seem to have made and dispensed their own medicines,
generally keeping an assistant to do their work. In process of
time some of these assistants started business on their own account,
while the busy physicians sent their “ bills ” or prescriptions to
them to be dispensed. We find that both physicians and apothe?
caries obtained their supplies of drugs from abroad through the
grocers, some of whom by devoting the greater part of their atten¬
tion to the drugs, became known as druggists. Hence, in 1606, we
find the grocers and apothecaries incorporated together. But the
number of apothecaries increasing, partnership was dissolved, and a
new company, the Apothecaries’ Company, was formed. The
company prospered and opened an establishment in Blackfriars for
preparing and compounding the medicines used by members. This
was begun on a small scale, but was afterwards mnch extended, and
was the foundation of the Apothecaries Hall.
Instead of confining themselves to dispensing, however, the
apothecaries started visiting and prescribing, and so became
formidable rivals to the physicians. To counteract this rivalry the
physicians started dispensaries theoretically to supply medicines to
the poor, but practically to get their own prescriptions dispensed
without the help of their rivals.
Let us, then, glance at the bodies of men engaged in the healing
art at this time. There were herbalists, who dealt in indigenous
plants, the drug-grocers, the chemists, or rather alchemists, who
made and supplied the few chemicals used, the apothecaries, and
the physicians, some of whom dispensed, but most of whom were
looking for some means of getting their dispensing done without
the help of their rivals. Dispensing was no light matter then.
Chemistry also was emerging from the darkness of alchemy, and
progress was being made beyond where Geber left off, eight
centuries ago. A demand was arising, fostered by such men as
Valentine and Paracelsus, for chemical substances to be used in
medicine. Valentine’s autimonial cups and pills are well known.
Hence we find a new class of men arising, who called themselves
chemists, who manufactured and sold their own chemicals and pre¬
parations. Mention may be made of three such establishments,
Wilson’s, one of which bore the sign of the “ Bell and Dragon,” and
Godfrey’s.
During the eighteenth century important reforms were made.
More attention was devoted to chemistry, the drug-grocers and
chemists seemed to have formed a class bearing the title of chemist
and druggist, and the pharmacopce'ias were much improved and
simplified.
In 1723, powers were given to the College of Physicians to
examine the medicine sold by apothecaries and destroy any unfit
for use. In 1748 the Apothecaries Company was empowered to
examine and license all practising as apothecaries within seven
miles of London. Under this act, the apothecaries claimed the
exclusive right to compound and dispense in London, a right they
failed to enforce against the ever-increasing number of chemists
and druggists. An attempt by the apothecaries to put a stop to
these formidable rivals failed, and it was left to the process of
survival of the fittest to decide the fate of the apothecaries.
The Apothecaries Act of 1815 empowered twelve examiners to be
appointed by the Apothecaries’ Company to examine and license all
selling drugs, etc., in England and Wales, physicians and apothe¬
caries alike. Five years’ apprenticeship was necessary.
In 1868 came the Pharmacy Act, which definitely settled the
qualifications of a qhemist and druggist.
88
PHARMACEUTICAL JOURNAL.
[Jan. 30, 1897
Next as to the pharmacy practised in these early days with no
help from the alchemists (I am speaking now of the fifteenth and
sixteenth centuries), it followed all the substances used were of
vegetable or animal origin, together with the few chemicals known
for centuries and a few mineral substances.
I am indebted to Mr. Lawton for the loan of a small book, appa¬
rently published about the seventeenth century, containing many
quaint prescriptions and their uses. It is entitled ‘ A Choice Manual of
Rare and Select Secrets in Physick.’ They appear to be rather
better than the usual run of preparations then made. Animal
patters of all kinds are not so much used. The author was extremely
partial to distillation. I read a few extracts : —
“ If you be sick after meet use this ” (a preparation of green
ginger in syrup, and cinnamon water).
“ To take away hoarseness.”
Take a turnip, cut a hole in the bop of it, and fill it up with
brown sugar-candy, and so roast it in the embers, and eat it with
butter.
“ For a Cough.”
Take Salad Oil, Aqua Vit©, and Sack, of each in equal quantity,
beat them all together, and before the fire rub the soles of your feet
With it. (A great waste of good stuff.)
“ An approved medicine for a sticking breath ” consists of
rosemary leaves and flowers boiled in white wine, and cinnamon and
benzoin added to be used as a mouth wash.
“ Against the biting of a mad dog and the rage or madness that
followeth a man after he his bitten.”
Take the blossoms of flowers of wild thistles dried in the shade
and beaten to powder, give him to drink of that powder in white
wine half a walnuts hell full, and in thrice taking it he shall be
healed.
Mr. Becger in the Pli. /., January 13, 1877, gives us some more.
The best water for the face ” is made from white of egg,
almonds, endiff boras, camphor zuchanimum, “ which is made with
alum that is relented,” white rose water, vinegar, and bean blossom
water. In preserving a youthful appearance, etc., it seems to have
been marly as effective as our modern toilet soaps.
“ An approved good water for the jarndines or the collick or con¬
sumption ” is made from a peck of snails washed in beer and
roasted, earthworms, angelica celandine, etc., nineteen ingredients.
“ Heat in the face” is cured by distilling strawberries and cream
with vine leaves, and using the water. “ Cock ale, and puppy
water ” are described. Andrew Borde, who lived at the beginning
of the sixteenth century, also gives us some quaint methods of
treatment ( Pli . J., 1871). He shows certainly much good sense.
I might here show of many salubrious medicines, but the best
medicine that I know is to let the matter alone. “ Abstinence is
the chief est medicine of all medicines.”
His treatment of itch is distinctly funny : “ This I do advertise
every man for this matter to ordeyne or prepare a good payre of
nayles to crack and claw and to rent and teare the skynne and the
fleshe, that the corrupt bloud maye runne out of the fleshe ; and
vse than purgacious and stuphes and sweates ; and beware, re-
uberate not the cause inwards with no ointment, nor clawe not the
skinne with fyshe fyngers, but wash the handes to bedwarde.”
And here we must leave the pharmacy of our forefathers. Crude
and unscientific though it was, made horrible with various animal
substances, and expensive with the diamonds, pearls, and rubies
occasionally used, we cannot help admiring the pictures these
quaint old books call up of the careful housewife with her pantries
stored up with herbs, in many cases collected and dried by herself,
who distilled her water for the benefit of poor suffering humanity.
And it seems to me that, considering the disadvantages under
which they laboured in those days of darkness, they showed a
disregard of trouble and a skill that would not disgrace any of us.
NOTES ON THE USES OF DRUGS.
Anesthetics and Narcotics.
Ancesthetics deprive the brain of all power of voluntary motion or
sensation. They include chloroform, ether, ethyl bromide, and
nitrous oxide, or laughing gas. The first effect of inhaling these
substances is stimulating, bright fancies and pleasant thoughts are
indulged in, and vigorous struggling movements are made. In the
second stage, anaesthesia comes on, and neither movement nor
sensation is possible.
Ether is by far the safest anmsthetic, it does not depress the
heart ; unfortunately it cannot be given either to young children or
bronchitic adults, because its vapours irritate the air passages and
lungs, causing bronchitis and pneumonia. Ether is inhaled from an
apparatus which regulates the amount of air mixed with it.
Chloroform is a handy anaesthetic, as it may be inhaled without
any apparatus ; a little poured out on a rag or towel is all that is
required. Chloroform should be used with caution, as it depresses
the heart. In every possible case ether should be used instead.
Ethyl bromide is official in the German Pharmacopoeia, but it
was employed first in England by Nunnely in 1849. It causes
anaesthesia more quickly than chloroform, and its effect is less
lasting. It is said to be less depressant to the heart than chloro¬
form, but it is to be avoided if the kidneys are diseased.
Nitrous oxide, or laughing gas, was discovered by Priestley in
1776. Sir Humphry Davy experimented with it on himself in 1799,
and discovered its power of anaesthesia. The first tooth was ex¬
tracted under its influence in 1844, but it did not become popular
until thirty years ago, when the Dental Hospital began to use it.
Anaesthesia is produced by laughing gas, partly because it causes
a condition of semi-suffocation, and partly by a special action on
the brain. Anaesthesia only lasts a few minutes and is quite free
from risk.
Narcotics are drugs which affect the brain, so as to produce
indifference to surroundings. At first they bring about a condition
of joyousness, where visions and fancies have free play, then an
emotional condition, and the memory of actual surroundings dis¬
appears, finally mental powers are lost, and voluntary motion is
badly performed, and a condition of mental unconsciousness and
semi-paralysis is produced.
The narcotics are opium and morphia, cannabis indica, bella¬
donna, hyoscyamus, stramonium. Opium and morphia are both so
important that their action on the whole of the body must be con¬
sidered. Opium has always been in use in the East, and is grown
in India and Turkey; it should contain at least 10 per cent, of
morphine.
If about one grain of opium be taken, a feeling of Men §tre and
general comfort are first produced, the mind then wanders and
pictures pleasant scenes, fantastic lights, weird fancies and figures
float before it. There is an indifference to surroundings, and a
partial insensibility to pain. Drowsiness now comes on, movement
becomes impossible, pain is not felt, finally sleep with quiet
breathing and steady pulse is produced.
If an excessive dose of opium be taken then sleep becomes so
heavy that the person cannot be aroused, nothing will induce move¬
ment, the skin becomes covered with a profuse perspiration, the
breathing becomes slow and shallow, the pulse grows weaker, the
face becomes livid and the pupils of the eyes contracted to the size
0f pinholes.
The action of opium is explained in this way, it first stimulates
Jan. 30, 1897]
PHARMACEUTICAL JOURNAL.
89
the brain, then later it paralyses the centres for motion and sensa¬
tion in the brain ; that is to say, unconsciousness supervenes ; later,
opium paralyses the spinal cord and reflex action is abolished, still
later the centres in the brain controlling the breathing and the
heart become paralysed, and death ensues.
Liniments and ointments containing opium are applied to the
skin to relieve the pain of lumbago and rheumatism ; it is inferior
to belladonna for this purpose.
An ointment of galls and opium cures the pain and prevents the
bleeding of piles.
Opium relieves cough of a nervous origin, but it is always used with
caution in chest troubles which are serious, because it dries up the
natural secretion and weakens the respiratory centre in the brain.
Opium makes the skin perspire. Ten grains of Dover’s powder
will often induce a good night’s rest, bring out a copious perspira¬
tion, and ward off a cold.
Opiam is a specific against all kinds of pain, and acts especially
well for the pain of colic, peritonitis, and cancer; it is also un¬
rivalled for producing sleep, and restoring the nervous system when
worn out by worry and care.
So pleasant is opium that a craving for it is easily established.
Whole nations, such as the Indians, give way to it.
Tolerance for the drug is quickly established. As much as half-
a-pint of laudanum can be taken by habitues without ill effect.
Morphine is more suitable for hypodermic injection, and is espe¬
cially used to relieve pain. It, unfortunately, confines the bowels ;
a small quantity of atropine is often prescribed with it to prevent
constipation.
Opium must be taken with caution when there is disease of the
kidneys, as it then may cause convulsions and unconsciousness.
Children are very sensitive to the influence of opium, which it is
to be feared is a constituent of many soothing powders, and is
answerable for much infant mortality.
Opium is more active in men than in women, yet it has very little
effect on the lower animals ; this is probably because the higher the
scale the greater the predominance of the brain and the influence
of opium on it.
Codeine is an opium alkaloid and is largely used in the treatment
of diabetes to lessen the amount of sugar in the urine. It is far
less narcotic than morphine, but seems to have a special action
on the nerves of the abdominal viscera. The other alkaloids of
opium are not extensively used.
Cannabis indica is the haschisch of the Orientals. Its effects are
similar to that of opium, but its physiological action has not been
so carefully investigated, Freusberg tells how a young Englishman
indulged in smoking Indian hemp. Alone in his rooms, he fancied
orchestral music filled his ears, and theatrical performances and
dancing figures presented themselves before his eyes. Looking into
empty space, he was charmed by seeing beautifully coloured land¬
scapes peopled with men and animals, while the murmurs of
running water and the wind-blown leaves of trees, mingling with
the strains of vocal and instrumental music, charmed his senses.
The tones of the music were soft and in harmony ; objects round
the room were, however, distorted, people appeared changed,
generally comical and repulsive.
After waking up from this condition his impressions were lively,
clear, and varied.
The tincture of cannabis indica is not a reliable drug, as its
composition is variable. It is used to relieve neuralgia and migraine,
and occasionally to induce sleep when opium disagrees.
Belladonna is a narcotic ; it also relieves pain when applied
locally, and checks all the natural secretions. When an excessive
dose of belladonna has been taken, the mouth becomes dry and
clammy, the pupils of the eyes dilate widely, the face is flushed,
and the pulse small and rapid. The person becomes first giddy,
then restless and excited ; he has hallucinations, and is delirious ;
he sees visions, and his hands are constantly moving as if he were
rolling bread crumbs or picking up bedclothes.
Belladonna is a very important drug and acts on many parts of
the body, and therefore is much used in medicine, and requires
consideration.
Ointment of belladonna, often mixed with equal parts of glycerin,
is often ordered to relieve the pain of lumbago, or the aching of a
rheumatic joint. The deeper seated pains of pleurisy and pneumonia,
the discomfort caused by palpitation of the heart, will often yield
to the application of a belladonna plaster. The tincture of
belladonna is sometimes used to induce sleep, but its action is very
uncertain, sometimes it is used to stop a troublesome cough, some¬
times to relieve palpitation of the heart and angina pectoris.
The extract of belladonna is put as an adjuvant in many
purgative pills, it makes their action certain and mild, and prevents
griping.
Belladonna stops the secretion of saliva, and is therefore a
powerful antisialic ; it also checks the formation of milk in the
breast, and therefore a plaster of belladonna or the ointment is
ordered after childbirth when it is not intended to bring up the
infant by the breast. Belladonna checks sweating, and is
frequently given to stop the night sweats of phthisis.
Belladonna also relaxes muscular spasm, and therefore hiccough,
spasmodic cough, asthma, and angina pectoris are relieved by it;
this drug also checks bronchial secretion and is given in cases
of bronchitis with excess of mucus.
Incontinence of urine in children is often treated with doses of
tincture of belladonna, it probably acts by soothing the mucous mem¬
brane of the bladder and checking the irritability of its muscles.
Belladonna ointment or atropine ointment applied locally to the
eye dilates the pupil and is much used by ophthalmic surgeons. In
many ways opium and belladonna are opposed to each other.
Opium contracts the pupils, belladonna dilates them, opium
in excess paralyses the heart, belladonna given at the same time
prevents this ; opium confines the bowels, belladonna relaxes them.
Opium is a diaphoretic, belladonna is an antidiaphoretic ; little
wonder, then, that belladonna is given in opium poisoning and vied
versd. Atropine is the active alkaloid, and is sometimes ordered in
preference to belladonna. Stramonium resembles belladonna in its
action, but is a far less powerful narcotic. It is used chiefly in
chest disease as an antispasmodic. Hyoscyamus also resembles
belladonna, but it is less active. It has, however, a special action
on the bowels, regulating peristalsis and preventing griping, and is,
therefore, added to many purgative pills.
(To be continued.')
Piperazine and Lysidine as Uric Acid Solvents. —Dr. Woodcock
Goodbody, as the result of an extended chemical examination of
the urine secreted under the influence of piperazine and of lysidine,
finds that both, when added to a urine tending to deposit uric acid
gravel, are capable of hindering the deposit on standing. The
experiments further show that lysidine exerts a more powerful
solvent action on uric acid than piperazine. Both, when taken
internally, increase the elimination of the acid, not by increasing
its formation, but by rendering the blood more capable of removing
it from the tissues ; so that prolonged administration of these drugs
causes a diminution of the quantity of acid eliminated by the
kidneys. Both are diuretics, and cause an increased output of
nitrogen, partly due to the increase of uric acid, and partly to the
ncreased volume of the urine excreted. — B. M. 2/96/903.
90
FHARxMACEUTICAL JOURNAL.
[Jan. 30. 189?i
THE STUDENTS’ PAGE.
THE STUDY OF THE B.P.
Acidum O/eicum. — The almost complete solubility of the lead
precipitate indicates absence of more than traces of stearic acid.
Potassium carbonate neutralises oleic acid, forming potassium
oleate. Any excess of carbonate is neutralised by acetic acid (to
prevent subsequent formation of lead carbonate), and the solution
yields a precipitate of lead oleate on addition of lead acetate. This
is soluble in ether ; lead stearate is not.
Acidum Phosphoricum Concentratum. — This contains ortlio-phos-
phoric acid. The glassy substance obtained by heating to low
redness the residue of its evaporation is metaphosphoric acid formed
by loss of water —
H3P04 - H20 = HPOg.
Albumin is precipitated by metaphosphoric acid. The latter is
formed when phosphoric anhydride is added to water (ride alterna¬
tive method of manufacture in B.P. ), but by subsequent boiling
metaphosphoric acid takes up water and forms ortho-phosphoric
acid. Phosphorous acid is indicated by precipitation with solution
of mercuric chloride—
H3P03 + OH2 + 2Hg012 = H3P04 + 2HC1 + 2HgCl.
This tendency of phosphorous to pass into phosphoric acid consti¬
tutes it a reducing agent. Note that the oxygen is obtained from
water, the hydrogen of which reduces the mercuric to insoluble
mercurous chloride.
Acidum SulpTiurosum.— Sulphurous acid wlffen pure gives no
precipitate with BaCl2, the barium sulphite being soluble in the
hydrochloric acid which rvould be formed at the same time —
HjS03 + BaCl2 = BaSO;, + 2HCl.
Chlorine oxidises the barium sulphite to sulphate in presence of
water, and the sulphate, being insoluble in hydrochloric acid, is
then precipitated — -
Cl2 + H20 + BaS03 = BaS04 + 2HCT.
Acidum Sulphuricum, — Stannous chloride is employed for the
detection of arsenic, which it reduced by SnCl* to the elemental
state, the stannous passing into stannic chloride. The chlorine
required for this change is obtained from the HC1 present, the
hydrogen of which forms the immediate reducing agent —
3SnCl2+6HCl + As 03 = 3SnCl4 -t 3HX> + 2As.
ON CHEMICAL EQUATIONS.
The use of equations is often sadly misunderstood by students*
By some they are exalted to a position of importance they do not
possess, being regarded as deciding the reactions they represent,
provided the two sides of the equation can be ‘ ‘ balanced. ” But
it cannot be too strongly emphasised that it is only feasible to
write an equation for a reaction when the conditions of the
experiment and both the initial and final members of the reacting
system are known. Under these conditions writing equations
becomes easy, and in no. way dependent upon remembering the
number of the reacting molecules. The equation becomes then a
kind of shorthand representation having a real value to the writer.
The student should, therefore, Carefully consider the substances
whose reaction is to be interpreted, and find out what becomes of
each of them, into what substances they are each and all converted.
Without this knowledge writing the equation becomes a matter of
juggling with figures and symbols, and however successfully he may
juggle in “balancing the equation,” his knowledge is in no way
advanced, but in many cases retarded.
Let us consider a few typical cases. (1st) The preparation of
chlorine by the action of hydrochloric acid on binoxide of man¬
ganese. When the mixture is heated chlorine is evolved ; man¬
ganese chloride and water are also formed — -
Mn02 + 4HC1 = MnCl2 + Cl2 + 2B.fi.
Now the interpretation of this reaction is far more important than
merely writing the equation. When an oxide is treated with an
acid, the usual reaction is to obtain the corresponding salt —
CaO + 2HC1 = CaCL + H.O,
and again — •
Cr.,03 -r 3H S04 = Cr.3S04 + 3H20.
But in the case of manganese binoxide we do not apparently obtain
the corresponding chloride, MnCl4, oxygen being divalent and
chlorine univalent. Why is this ?
When manganese binoxide is added to strong hydrochloric acid
in the cold, only a trace of chlorine is evolved, although the oxide
dissolves. When heat is applied, chlorine is given off and man¬
ganese dichloride is left in solution, as shown by the previous
equation. The explanation is this : before the mixture is heated
the chloride corresponding to the binoxide is really formed —
Mn02 + 4HC1 = MnCl4 + 2H..O.*
On the application of heat this tetrachloride decomposes, forming
the lower chloride and free chlorine —
MnCl4 = MnCl2 b CU
A' knowledge of the intermediate stages which often occur between
the initial and final conditions represented by an equation should,
therefoi’e, be obtained. It gives the student an extended acquaint¬
ance with chemistry, and the equation then follows as a representa¬
tion of real knowledge, without which it is comparatively valueless.
Let us consider next the formation of ferric sulphate from
ferroiis sulphate by oxidation with nitric acid, as in liquor ferri
persulphatis. The substances reacting are ferrous sulphate, sul¬
phuric acid (the importance of this will be seen later), water, and
nitric acid. The reaction results in the formation of ferric
sulphate, nitric oxide being given off. First, compare the
formulae for ferrous sulphate (FeS04) and ferric sulphate (Fez3SOj.
It will be seen that the ratio of S04 to Fe is greater in the
latter than the former. This extra S04 has been derived from the
sulphuric acid added. Nitric oxide is evidently obtained by the
reduction of nitric acid, the oxygen lost by the latter forming
water with hydrogen from sulphuric acid, the sulphuric radicle of
which has gone to raise the ferrous to ferric sulphate. Consider
now the amount of oxygen obtainable from nitric acid, UNO,.
Nitric acid can be obtained by adding nitric anhydride, N-A, to
water,
N205 + H20 - 2IiN03,
and was formerly regarded under the Berzelian system as
11,0 'N 205 . In all reductions to which nitric acid may be sub¬
jected the hydrogen comes out combined with its equivalent of
oxygen as water. The amount of oxygen yielded by the nitric
acid therefore depends entirely upon which of the lower oxides of
nitrogen is obtained. Nitric oxide is obtained in the present case,
and a simple inspection of the formulas shows that every two mole¬
cules of nitric acid yield three atoms of oxygen, 2HN03(Ho0,Ni0.-)!
giving H20‘2N0-30. If nitric peroxide were formed, only one
atom of oxygen would be available for oxidation, H20\N205 giving
H,0'2N0/0. The equation becomes therefore a simple matter —
3HN°.{n!o, jUJO
H*s0*{s<5.
It is evident that we cannot take less than two molecules of
nitric acid, which yields three atoms of oxygen. These three
atoms of oxygen combine with six atoms of hydrogen. We must
therefore have three molecules of sulphuric acid and consequently
three S04 groups. Two molecules of ferrous sulphate require one
S04 group to convert them into ferric sulphate. The outcome of
this is to show that two molecules of nitric acid suffice to raise
6FeS04 to 3Fei3S04, and the equation in one line becomes —
6FeS04 + 3H2S04 + 2HN03 = 3Fe_3S04 + 2N0 + 4H_0.
THE FLOWERS OF JANUARY.
Jasminum nudijlorum is a common garden shrub likely to puzzle
the student on account of the absence of leaves when the plant is
in flower, and because the yellow corolla has often six or seven parts
instead of four or five. The stem, however, shows a dicotyledonous
structure, and there are rarely more than two stamens. It belongs
to the Oleacea, the Oleaceae belong to the sub-class Corolliflora?,
which has a regular corolla, two stamens, and a two-celled ovary
with few seeds (usually one to four) in each cell, and is thus easily
distinguished from the Labiate and Scrophulariaceous flowers with
two stamens.
Pemnus boldus (Monimiaceae) is another medicinal plant in flower
this month. It grows well at the Regent’s Park Botanic
Gardens. This family is allied to the Laiuraceae in some respects,
but differs in the opposite leaves and albuminous seed with a
small embryo. The flower is described in Ph. J. [3], vol. vii.,
p. 609 to 610. Both the Monimiacese and Lauraceee belong to the
Corolliflora'.
Jan. SO, 189?]
PHARMACEUTICAL JOURNAL.
91
Pharmaceutigal Journal
A Weekly Record of Pharmacy and Allied Sciences.
ESTABLISHED 1841.
Circulating in the United Kingdom, France, Germany,
Austria, Italy, Russia, Switzerland, Canada, the
United States, South America, India,
Australasia, South Africa, etc.
Editorial Office: 17, BLOOMSBURY SQUARE, W.C.
Publishing aqd Advertising Office : 5, SE^LE STREET, W.O.
LONDON : SATURDAY, JANUARY 30, 1897.
THE PURITY OF FOOD AND DRUGS.
It has come to be regarded as a necessary evil in these
degenerate days that the British taxpayer should be freed as
much as possible from tlie necessity of initiating self-protec¬
tive measures. Hence the enactment of Statutes
directed against tlie exercise of individual discretion — by
teaching people to rely more and more on elected bodies and
their paid agents — is hardly to he wondered at. As a result
of this system the individual gradually becomes unaccus¬
tomed to act for himself in certain directions, and ultimately
he may he rendered unfit to protect himself entirely. In no
instance is this tendency so strongly marked as in connection
with the purity of foodstuffs and drugs. There is some reason to
believe that, years ago, sophistication was practised to an extent
that can hardly he conceived as possible to-day, and that the
worstcaseof adulteration occurring at this latter end of thenine-
teenth century would have been regarded as an exceedingly
mild one in earlier times. And yet, in spite of this, people
thrived in those days and transmitted to their descendants
at least as good physical constitutions as they inherited.
The reason is perhaps not far to seek — our ancestors who
were fit to survive carefully avoided inferior, sophisticated
stuff. Not that they organised auy such elaborate system as
obtains now, or that, as individuals, they were capable of
acting as their own analysts and adulteration detectors. The
means resorted to were such as were bound fo fall out of
use sooner or later, because they were too simple. The pur¬
chaser who wished to avoid shams paid a fair price for what
he wanted, at a place where experience had led him to
expect he could depend upon procuring a sound article,
and — human nature being such that sellers prefer on the I
whole to walk straight so long as they are not beaten down
and worried about the means of existence — the purchaser
was not often disappointed.
This old-fashioned plan — as old as human society — is prac¬
tised by some people even now, in spite of the fact that
they are perforce obliged to contribute towards tlie expense
of maintaining an army of spies and analysts for tlie protec¬
tion of weaker elements in Society. The latter, by con¬
tinually buying in the market where the lowest price pre¬
vails, offer a premium to competition, of which, according
to John Bright, adulteration is a form ; they thus wage an
unceasing war with shopkeepers, who, owing to lack of
u^nion in their ranks, are sooner or later ground down to
bottom prices and even lower, the sale of inferior and
adulterated goods then taking place as a natural
corollary. In the ordinary course of events this state of
affairs would soon right itself, as the consumers of less pure
and nutritious articles would be less fitted to survive than
those who declined to ruin their health and stamina even to
save their pockets. But false humanitarian motives have
come into play at this point, and the best of our race must
needs be taxed to help maintain the most incapable alive.
Moreover, the ranks of the helpless soon swell, as those in
the borderland between the naturally dependent and inde¬
pendent lapse into a worse condition rather than a better.
The result is that, at the present time, many
thousands of naturally generous-minded people, who
would have been quite capable a quarter of a century
ago of protecting themselves in the matter of food and
drugs, have become comparatively helpless in that respect.
Thoughtlessly trusting to the adulteration Acts for protection,
such people are deluded into the belief that all foodstuffs
and drugs they see exposed for sale, however low-priced,
must be genuine, and therefore as fit for the desired pur¬
poses as the more expensive articles. It is not surprising
then that the sale of goods just good enough to meet official
requirements increases, and the public is worse off generally
than at the time when adulteration was more openly and
extensively practised. The difference between good and bad
was then strongly pronounced, hut now we have one gradu¬
ally shading off into the other, and the medium_or second-
rate article sells best of all.
All this must, of course, he of very great disadvan¬
tage t ) the public ; hut, unfortunately, the retrograde
tendency of grandmotherly legislation results in moral
emasculation, and the development of a somewhat inverte¬
brate type to which the support afforded by the ingenuity of
tinkering legislators becomes a necessity, Accordingly, the
worse the evil becomes the more we must legislate, establish
standards, and worry the shopkeeper who depends upon the
trade of the incapable, on all hands, until the quality of his
wares is maintained at a dead-level of uniformity, and that
the minimum point. Last year a Select Committee
on Rood Products did its best to ascertain how existing
Acts could be modified to the public advantage, and, so
far as making the best of a bad job goes, the report of that
Committee indicated what are probably the best means of
remedying certain defects. Bat whether the members of
the present Government disapprove of the means sug¬
gested, or object on principle to the regulation of the quality
of food by legislation, when it is such an easy thing for
everyone to regulate it for himself, there appears to be no
immediate intention on the part of those at present responsible
for the direction of public affairs to take part in the tinker¬
ing process. In spite, therefore, of the clamours of Mr.
Kwarley and his supporters who, for reasons best known to
themselves, attempt to make capital out of the situa¬
tion, the Government does not intend to move in the
matter at present. We must own to a lingering desire
that if anything is to he done at all, the Government should
act directly in the matter ; we should like also to see legis¬
lation respecting drugs separated from that dealing with
foodstuffs \ but on the whole there is not much to lose
from keeping the whole matter open for some time longer,
even though public analysts may continue to lament the
lack of satisfactory standards and the public require to look
better after their own interests
PHARMACEUTICAL journal.
92
ANNOTATIONS
Complaints against Examiners, like that in a letter on page
100, are not rare, though they are not often committed to paper and
sent for publication. But in most, if not all, instances there is usually
some factor of which the complainant is not cognisant, which totally
invalidates his case, for a candidate is rarely in a position
to form a reasonable estimate of his own fitness to pass
an examination ; the best men being unnecessarily afflicted with
doubt, and those far down in the list of merit as conceitedly cer-
t ain of a favourable result. The grievances of rejected candidates
may therefore be regarded as invariably requiringmuch more than the
proverbial grain of salt to season them. Nevertheless, since examiners
are but human, there must always be a lurking possibility of
an appearance of unfairness, especially if questions be asked which
are outside the limits of the examination syllabus. Though
inability to answer such questions may carry with it no “black
marks,” the man who has travelled far beyond the limits of
the syllabus in his studies and solves the problems with ease may
thus put himself in a much better position ; but a candidate who
happens to be “ plucked ” after such a question has been put to him
is almost certain to attribute his ill-luck to the question which he
thinks he ought not to have been asked.
The Irish Examinations are also occasionally the subject of
criticism on the part of candidates, with what show7 of reason it is
impossible for us to say. One correspondent has sent the following
facts for publication “At the Irish Pharmaceutical Licence
examination, a candidate took a certain number of marks, and
had the honour of first place ; exactly twelve months later,
another candidate — a fellow assistant of the former— took
at the same examination no less than twenty marks
more than his fortunate comrade, and was rejected.”
We make no comment on this statement, being unfamiliar with
the working of the Irish examination system. On the face of it,
however, the stoi'y is a curious one. And yet, though our
informant may be quite correct in his facts, it is both possible and
probable that there may be an adequate explanation. In spite of
his high total, the second candidate may have done very badly in
some particular subject. But, as matters stand, it is not to
be wondered at if he feels unduly despondent.
The Junior Pharmacy Ball will be held for the sixteenth
occasion, on Wednesday, February 10. The first dance will com¬
mence at the Portman Rooms at 9 p.m. , the musical accompani¬
ment being provided by Mr. Mortlake Mann’s Orchestral Band.
The support of Mr. Walter Hills, President of the Pharmaceuti¬
cal Society, Mr. Michael Carteighe, Mr. Arthur L. Savory, and
other prominent pharmacists has been promised, and tickets
(7*. 6 d. each) may be obtained from any of the numerous stewards.
They may also be obtained from the honorary secretary, Air. H.
Arliss Robinson, 29, Chapel Street, Belgrave Square, S.W., who is
anxious that the Ball should be an unqualified success during this,
the last year, of his secretaryship. We therefore call upon his
friends, in the words of Dickens, to “ rally round him” and show
their appreciation of the good service he has rendered in the past.
A Swansea Chemist who has been unfortunately obliged to
have recourse to the Bankruptcy Court, appears to have suffered
in great measure through not sharply looking after his own
interests. According to his own account, he bought the stock of
his shop from the former tenant for three hundred pounds, and
also gave two hundred for the goodwill on the representation that
the takings were from fifteen to twenty pounds a week. After
taking possession he found that the books had been “cooked,” but
[Jan. 30, 1 897
the former proprietor had left the country, so that he could not be
brought to account. The unlucky purchaser had valued the stock
himself at three hundred pounds, but on taking possession he
found some of the stock had disappeared and the value he actually
received was not more than one hundred. The Registrar having
observed that an elaborate fraud had evidently been practised on
the debtor after he saw the premises first, the examination was
provisionally closed. The former proprietor is still wanted.
Deaths from Misadventure are reported in which the fatality
has been due to chlorodyne, laudanum, mercuric chloride, and
A.C.E. anEesthetic respectively. The chlorodyne was taken in
large doses to induce sleep by an Islington cellarman, aged 43,
and he appears to have swallowed the contents of an ounce bottle
at once. At Headingley, a man, aged 35, had spoiled his whisky
toddy by the addition of laudanum, and did not wake after imbib¬
ing the mixture. The evil habit of self-doctoring was responsible
for the third case, in which a Stockton engineer, aged 41, who had
been in the habit of taking bromide as a nervous stimulant [sic),
took corrosive sublimate instead, and obtained a more definite result.
Finally, a man, aged 54, died at the Leeds Infirmary whilst under
the influence of the alcohol-chloroform-ether anaesthetic.
The Sweet Lavender Scare created by articles which recently
appeared in the daily press on the production of English lavender oil,
has caused Alessrs. Jakson and Co. , of Mitcham, to write in reference
to this subject, and they point out that there is no
foundation for the statements as to their cultivation of
lavender at Mitcham being abandoned or reduced. As large
growers and distillers of lavender and peppermint, Messrs.
Jakson have this year put an 1 additional ten acres of land
under cultivation, and the cultivation of lavender can be further ex¬
tended in other parts of Surrey. English lavender water is now
exported to all parts of the civilised world in increasing quantity)
and as a proof that it stands unrivalled for excellence, Alessrs.
Jakson mention that they have obtained the highest awards at
international exhibitions where they have exhibited, This
industry gives employment to a large number of hands, and there
is no reason to fear that it will decline.
Sperm atozoids from the Pollen Grain would appear to be
the fertilising agent in the case of GingJco biloba, the discovery that
this is so being attributed to a Japanese histologist. If this report
be a correct statement of fact, a way should be opened to further
important discoveries, as the plant referred to will thus form a fresh
connecting link between the Cryptogams and Phanerogams.
The City and Guilds ok London Institute has had its financial
affairs investigated by a special committee, with the result that it
is shown to have well and economically carried out the objects for
which it was founded, The report of the Finance and Administra¬
tion Sub-Committee commences with a brief survey of the history
of the Institute, and then proceeds to deal with its current expenses.
The approximate gross cost per student during the past two finan¬
cial years- taken together is shown to have been £54, as against an
original estimate of £75, whilst the net cost was £31, as against an
original estimate of £50. The students devote their whole time to
study, and attend the Central Technical College close upon 1000
hours during the session. These figures, therefore, compare very
favourably with those of similar institutions in England, America,
Germany, and Switzerland. The Sub-Committee on the Educa¬
tional Work of the College also expresses the opinion that the work
of the institution has been eminently successful, and thinks the
City Guilds’ Institute is to be congratulated on what it has accom¬
plished, the results achieved being regarded as fully commensurate
JAN. 30, 1897]
PHARMACEUTICAL JOURNAL.
93
with the expenditure involved. It is believed that, in the near
future, the College will be found too small for the number of
students likely to seek admission, and that the question of ex¬
tending the building may before long have to be considered.
The Active Principle of Indian Hemp is the subject of a com¬
munication to the Lancet by C. R. Marshall, M.B., who points out
that the want of uniformity in the preparations of Indian hemp has
so often led to serious consequences in practice that many practi¬
tioners have discarded the drug as worthless or dangerous. The
principal natural products of the Indian hemp plant — charas,
ganja, and bhang — are briefly referred to, after which is given a
historical summary of researches that have been undertaken in
connection with the plant. Then follow some records of personal
experiments with a preparation to which the author applies the
name of cannabinol, the results of which are thought to
establish its activity sufficiently to justify its introduction into
therapeutics. Uncontrollable mirth and inability to fix attention
on anything were marked symptoms produced by the drug, acute
intoxication, slurred speech, and ataxic gait being accompanied by
freedom from all sense of care and worry. Hallucinations were
not indicated, the sense of happiness manifested seeming rather to
result from absence of all external irritation. There was a com¬
plete loss of time relation, the impression being that of living in a
present without a future or a past. In fact the symptoms recorded
forcibly recall accounts of the action of “ hashish,” which it has
been customary to relegate to the region of romance.
A Great Terrestial Globe is likely to be constructed for
exhibition in London, on the scale of 1/500, 000th of Nature.
The globe will have a diameter of eighty-four feet, and show
the earth’s surface, on a scale of about eight miles to the
inch. London, for instance, will cover a space rather larger
than a penny. Spectators will view the globe, certain sections of
which have already been prepared by T. Ruddiman Johnston, from
a spiral gallery running round it, and as the globe slowly revolves
every portion of its surface will successively come into view.
The Proprietary Articles Trade Association has been
favoured with a notice by the Daily Telegraph, in which the fact
is noted that within a year of its formation the Association has
enrolled over seventeen hundred members. But, it is observed,
the outside public can hardly be supposed to have any hope of
pecuniary advantage from this movement, and it is mentioned
that some influential chemists are opposed to the organi¬
sation, on the ground, as stated by one of them, that it
is “ inviting our trade to combine in helping our worst enemies,
the proprietary medicine men, the men who are gradually
gripping us by the throat and will make our business one simply
to stock their goods and pass them over to the public at a
minimum of profit.” The quotation is from a letter by Mr. G. R.
loulston, of Hull, which appeared in our issue for January 9, and
has apparently attracted as much attention outside the trade as
within, if an opinion may be based on the scanty number of
responses evoked. Possibly, however, correspondents may have pre¬
ferred to communicate their views privately to Mr. Foulston, a course
which possesses certain advantages in dealing with so delicate
a subject, and might more frequently be adopted with advantage.
The Capacity of Dispensers to turn out bottles of medicine
was the subject of discussion at a recent meeting of the Camber¬
well Board of Guardians. A medical practitioner said a man could
turn out five hundred bottles daily, but he must work continuously,
and another local oracle, whilst scouting the idea that the thing was
impossible, mildly remarked that he thought it was too much. On
enquiry, however, it appeared that three hundred of the daily half
thousand were simply filled with a stock mixture, and so the mystery
of how the trick is done was solved. Patients in the Camberwell
district must be afflicted with a strange sameness of symptoms, or
it may be that residents in that part of South London have
acquired a t^ste for the stock mixture in question, and take care
always to require the same remedy. The outcome of the
discussion was a decision to provide the dispenser with an assistant,
since the Local Government Board do not allow of his salary
being increased however many the bottles he dispenses (?) daily.
The Existence of Memory' in Fishes is a moot point, but
there is a general opinion that fish have some sort of memory, and
they can recognise people, know how to find or to avoid places
where they have formerly made some experiences, whilst fish which
have once escaped the rod are supposed to know the bait,
etc. Professor Ludwig Edinger thinks it is highly desirable that
all experience of this kind should be collected, in the interests of
comparative psychology. All experience in man and in the higher
animals, he points out, has led to the conclusion that the function
of memory depends on the action of the brain cortex, but during
recent years it has been proved that fish have no brain cortex at
all, being the only existing vertebrates in that condition. If it
could be proved beyond the possibility of doubt that fish really
have a memory, that they gain experience and can make use of it,
then the till now general opinion that memory has its seat in the
brain cortex will have to be relinquished, and it is therefore
extremely important to have an entirely new set of experiences
to theorise on. Professor Edinger accordingly asks all anglers
and naturalists to communicate to him, at 20, Gartnerweg,
Frankfurt, Main, any experiences they may have had, request¬
ing them particularly to take nothing for granted, as the smallest
observation may prove of the greatest importance.
Here is a Splendid Chance for Anglers to tell their
pet tales, the Lancet remarks, and to throw light on this
interesting question. Many incidents which commonly occur
to anglers would decidedly go against the theory that fish
have memories. Thus, a fish which has had a fly broken in its
mouth will often immediately take another, and on being captured
the broken one may be found still sticking in his mouth, and then
it is well known to fishermen that a pike which escapes while it is
being played will often again ferociously seize the bait if it be at
once temptingly offered him. Such well-known facts as these do
not at first sight point to any highly-developed powers of reason¬
ing in the fish, but before drawing any conclusions from them,
another factor — that of sensibility — must also be taken into con¬
sideration. It is highly probable that a fish hooked with a small
fly-hook in a gristly part of the jaw feels little or no pain, and if,
therefore, the hook immediately breaks, the fish possibly looks
upon it as a very slight inconvenience, which in no wise need
hinder him from continuing his meal.
The Eighth International Pharmaceutical Congress is
announced to be held in Brussels during August next, and the
Secretary of the Belgian General Pharmaceutical Association asks
us to lay before our readers certain resolutions in connection with
the matter. These resolutions, however, and “divers” docu¬
ments concerning the approaching Congress, which the Secretary
says lie has enclosed with his letter, are unfortunately missing.
For the present, therefore, readers desirous of learning more about
the matter must communicate with the Secretary, 102, Chaussee
de Wavre, Brussels,
94
PHARMACEUTICAL JOURNAL,
[Jan. SO, 1897
SWEETINGS Op SCIENTIFIC SOCIETIES
Chemical Society, Thursday, January 21.— Mr. A. G.
Vernon Harcourt, F.R.S., President, in the chair. — The
meeting was a very large one : the papers brought forward
were of considerable interest to chemists generally, and they
were, moreover, a relief to the ennui caused by a prolonged diet of
“ organic” chemistry, with its endless accompaniment of formula1.
While the minutes of the previous meeting and the certificates of
candidates were being read, there was a din caused by the general
conversation going on as if the Fellows were entirely forgetful that
the meeting had been opened ; indeed, this is the case at all
meetings, but on this occasion Professor Thompson’s laudable
efforts to pronounce the names of some Japanese candidates at
once attracted attention, and the audience was duly tickled.
Immediately after the transaction of formal business, the Presi¬
dent called upon Mr. W. A. Shenstcne to communicate to the
Society the results of his “ Studies of the Properties of Highly-
Purified Substances.” Part I. dealt with —
The Influence of Moisture on the Production of Ozone from
Oxygen and on the Stability of Ozone.
Mr. ShenSTONE is gifted with a pleasing voice, and, in addition, an
attractive style of delivery, so that his paper, which occupied over an
hour of the meeting’s time, was listened to with great attention.
He referred at the outset to the statement that chemical reactions
could not occur in the absence of water or moisture. He was
inclined to take exception to this however as an absolute rule, and
whilst admitting that most reactions were controlled by moisture,
he held that some are certainly not. Andrews and Tait, workers
on the subject of ozone, emphasise the importance of using dry
oxygen for the production of ozone. Figures of the elaborate
apparatus used were projected on the screen, and the author referred
to the assistance he had derived from one of his pupils who was an
expert glass-blower. Indeed the apparatus which was displayed on
the bench, and which it was observed the President handled very
fondly, was all that the most fastidious chemist could desire.
Most of it was made of hard Jena glass, and so Mr. Shenstone
was enabled by its use to perform experiments which under other
or ordinary conditions could never have been done. Roughly the
apparatus consisted of an ozone generator, a manometer, drying
tubes of phosphorous oxide, and a receiver. After repeatedly
exhausting and heating this apparatus, a proceeding involving
weeks and even months, it was filled with oxygen, re-heated, and so
on for a great number of times. In this way the amount of gaseous
impurities was reduced to a minimum. On ozonising the oxygen,
he had obtained on an average something like 13 '6 per cent.,
the least successful experiment showing a percentage of 13 ‘3.
In all the experiments there was never any difficulty experienced
in measuring the amount of ozone obtained, but in presence of
moisture the volume of ozone was diminished, and it was
found that this was brought about by the ozone decomposing.
An ingenious contrivance was employed for heating the ozone
generator in a perfectly gradual and uniform manner, viz., an
electric current, which was led round the generator in a spiral.
Mr. Shenstone was enabled in this way to warm the tubes so
gradually that no hesitation was felt in bringing the actual flame
in contact with the apparatus for further heating. A temperature
approaching 400° C. was employed, and was maintained for four
hours. Pumping operations were continued for a week, eight
hours’ heating again, and then more pumping until the oxygen had
been reduced to this tension, ‘000,000,001 Mm. There was
laughter as Mr. Shenstone seriously put these figures down on the
blackboard, but he smiled when he said that they might be taken
with a grain of salt. He had obtained similar results by using
Ruhmkorff or Tesla apparatus. Absolute drying, he said, would
result in the production of no ozone at all.
The second part of the paper was on —
The Behaviour of Chlorine, Bromine, and Iodine
with Mercury.
Particular precautions were taken to ensure the purity of the
chlorine used. Hydrochloric acid especially was an impurity liable
to be present, and difficult to get rid of. Pure chlorine, however,
was eventually prepared from silver chloride by electrolysis (Arm¬
strong’s suggestion), but a serious objection to its employment was
the formation of the silver tree. This difficulty, however, was
disposed of by reversing the current and thus blowing the “ tree ”
away. The experiments involved in this work were very laborious.
The apparatus was exhausted and heated as for ozone. The
bromine used was prepared by placing it in a large excess
of potassium bromide, heating to 70° or 80° for a day and then
fractionating.
Three different specimens of mercury were employed : —
1. By electrolysis of specially prepared nitrate.
2. By dissolving mercury in sulphuric acid, precipitating by
hydrochloric acid, the mercurous chloride then converted into
mercuric salt, treated with sodium carbonate, the oxide obtained
and the mercury distilled therefrom.
3. From oxide of mercury converted into nitrate, then into oxide
and distilled. The purified mercury thus obtained left no stain on
a glass surface. It was dried in phosphorous oxide. The drying
of the halogens occupied some seven or eight months. In every
case the action was complete.
Part three was on — -
The Behaviour of Chlorine under the Influence of the
Silent Discharge of Electricity and in Sunlight.
A very minute contraction takes place, but Mr. Shenstone thinks
it just possible that a slight change in temperature might have
produced it. The chlorine was dried by passing through phos¬
phorous pentoxide. Impure chlorine shows great differences in
expansion. The experiments do not agree with all the theories
as to the influence of moisture on chemical reactions.
In the discussion which followed the reading of this paper there
was nothing but compliments to Mr. Shenstone, not only for the
admirable results he had obtained, but for the excellence of the
apparatus which had been made under his guidance. Professor
Tilden doubted if anyone present could have performed the
experiments, even if the apparatus were provided.
At this stage the President intimated that the Treasurer,
Professor Thorpe, had a statement to make which he felt sure the
Society would consider very satisfactory. Professor Thorpe then
stepped up to the platform and said that a cheque for £1000 for
the Research Fund, without any restrictions, had been received
from a certain gentleman whose name he mentioned. The thanks
of the meeting was cordially given for this generous gift.
The next paper was on—
The Action of Diastase on Starch,
Part III. , by A. R. Ling and J. L. Baker. The authors have
isolated two new substances from the products of the hydrolysis
of starch agreeing with Brown and Morris’s malto-dextrin, C1,H.,!JOn
(C19H 0O10)j. The statements in this paper are very much at
variance with some of the work by Messrs. Horace T. Brown and
Morris, and the reading of the third paper by the latter gentle¬
man on-.
The Solution-Density, and Cupric Reducing Power of
Dextrose, Levulose, and Invert-Sugar.
resulted in rather a hot discussion on these kindred subjects.
This last paper was got through very hurriedly, as it was already
ten minutes to ten. It is really supplementary to the papers
brought before the Society some time ago. - Levulose and dextrose
are prepared by the most approved methods, and the solution
densities carefully determined. The authors are thus enabled to
obtain divisors. The cupric reducing power was determined
by the method formerly described, and the conditions of time,
mode of heating, etc., were precisely as before. Levulose and
invert-sugar have a lower cupric reducing power than dextrose.
— Dr. Morris, who read this paper, regretted that Mr. Ling
did not go more fully into the properties of the substances
he had isolated, indeed he was quite unable to follow him
closely, but from what he had picked up he considered that
Mr. Ling had brought forward no evidence to prove his case.
Dr. Armstrong rose and spoke in defence of Mr. Ling, saying
that he had obviously, and unfortunately for himself, no gift in
communicating the results of his important work to the Society in
abstract, but he had no doubt that Dr. Morris on reading the entire
paper would be convinced of the accuracy of Messrs. Ling and
Baker’s work.
Royal Institution, Friday, January 22. — Professor Dewar
delivered a lecture on —
The Properties of Liquid Oxygen,
and demonstrated a number of experiments with that
liquid. The subject was treated in an exceedingly inter¬
esting manner, the experiments being of a most delicjit§
Jan. «0, 1897]
PH A RM ACEUTICAL JOURNAL.
95
nature. In commencing, Professor Dewar observed that five
years ago he had lectured upon the properties of liquid oxygen,
chiefly dealing with its magnetic properties, and after that
interval he was again referring to the subject which had
been studied by scientists for a long series of years.
Knowledge of the subject has accumulated very slowly, and al¬
though we have had a knowledge of liquid oxygen for some
fifteen years, we have not yet exhausted its mysterious properties.
The most important property is its stability of temperature at a
constant boiling point, this being of value in a variety of experi¬
ments. The boiling point of ordinary air and that of liquid oxygen
differ considerably, the liquid oxygen having a fixed boiling point,
while that of air varies according to the various impurities which
mix with it. Several experiments were made showing the
variability of the boiling point of air and the stability of that of liquid
oxygen. A series of observations of low and high temperatures
followed, Professor Dewar explaining the electric thermometer
used in the tests, and showing by a number of experiments
"how by the aid of liquid oxygen low temperatures can
be determined, and how, having got the standard of tempera¬
ture, the specific heat of bodies can be ascertained. He
then proceeded to illustrate by experiments, how, in the
event of the earth cooling down to the temperature of the moon,
the extremely low temperature would cause the absorption of a
large amount of air, and also the means by which he could ascertain
the thickness of the liquid air layer. Other experiments followed
with reference to the origin, etc., of certain curious atmospheric
bands.
THE WORLD Op PHARMACY.
- ♦- - -
BUSINESS MEETINGS.
Chemists’ Assistants’ Association, Thursday, January 21.
— Mr. Charles Morley, President, in the chair. — At this meeting
a departure was made from the usual style of papers read before
the Association which deal chiefly with subjects of pharmaceutical
and scientific interest, an address being delivered by Mr. E. W.
Richardson, assistant editor of the St. James's Budget , on —
The Birth of an Illustrated Journal.
Mr. Richardson began by remarking that he made no apology
for bringing such a subject before an association of gentlemen
whose business was usually of a more scientific character, inasmuch
as he believed that what was of interest to other men would
.equally interest them. He then went on to explain the duties of
the editorial staff connected with the production of an illustrated
journal, commencing with the most important person, that
“ necessary evil,” the proprietor, concluding with the office boy.
The business of running a newspaper is very much like running a
grocery establishment or business of any kind, there being always
a certain daily routine of duties, which become as methodical
and systematic as those of other businesses. — The lecturer
then described the getting-up of a journal from the pre¬
paration of the “raw news” as it evolves from the tape
machine or other instrument for the transference of news, to its
appearance in the clean pages of the published journal. The
methods of preparing zinco line blocks and the more costly half¬
tone blocks for the illustrations were also clearly described. The
subject was made doubly interesting to those present by the ex¬
hibition of “copy,” “galley proofs,” “pulls,” “blocks,” etc.,
actually used in bringing out the issue of the current week, and
the various styles of issuing “ copy ” employed by the numerous
press agencies to render their news easily distinguishable in the
'hurry and rush of a newspaper office. At the conclusion of the
address, Mr. Richardson having invited criticism either on ariy-
thing he had referred to or on the style in which his particular
journal was published, Messrs. R. G. Guyer, 0. Morley, E. W.
Hill, Strother, H. H. Robins, Melhuish, and C. E. Robinson
asked several questions relating to the printing of the Budget,
the most important being as to the use of the “s” after the
apostrophe in “ St. James’s,” and the production of the coloured
•Christmas number of the Budget, Mr. Robins wishing to know why
it could not be printed as well and as cheaply in England as in
Holland. — Mr. Richardson, in reply, explained why the “ s’s ” was
adhered to, stating that, although grammatically wrong, it was an
old custom which was continued more as a distinctive mark than
for any other reason. It was a case of unadulterated conventionalism.
With regard to coloured picture printing, they must take into con¬
sideration that naturally developments in printing should take
place in the country in which it was first invented. Colour working
is undoubtedly done better and cheaper in Holland and Germany
than in England. As far as his journal was concerned, they had
tried to get the work done in this country, and had given it to an
English firm to do, but he was afraid this work ultimately found its
way to Holland.
Sheffield Pharmaceutical and Chemical Society,
Wednesday, January 27. — Dr. Dyson in the chair. — Mr. George
Swainson, F.L.S., of Bolton, delivered a most interesting lecture
on — -
Corals and Coral Islands,
the subject being well illustrated by a series of beautiful lantern
slides. Those who had anticipated an interesting hour and a half
were by no means disappointed, for the subject was treated in so
pleasantly chatty and withal lucid a manner that all persons, how¬
ever ignorant of or well versed in the theory of the development of
this wonderful ocean growth, were afforded an opportunity in the
first place of gaining a knowledge of a matter enveloped in a good
deal of mystery, and in the second of adding to their store of facts
the results of the latest and most thorough investigation by those who
have devoted to the work many years of patient study and observation.
At the outset, Mr. Swainson said he hoped this lecture on “ Corals
and Coral Islands” would be of interest to Sheffield chemists,
because the subject had been now for ten years exciting the
deepest interest amongst scientific men. They had in these dis¬
cussions evidence of a great personality. For some forty years
the influence of one man had been predominant. He referred to
the late Charles Darwin, and said that for forty years his pro¬
nouncements on the subject of corals had gone undisputed, no one
seeming to dream of doubting anything he had written on the
subject. He supposed the scientific world was too busy in the
discussion of the evolution theory, the survival of the fittest,
natural selection, and so on, to think of corals. It was not until
the “ Challenger” survey that Dr. Murray began to whisper some¬
thing in the way of contradiction. Darwin’s theory was that coral
formations were effected by the earth’s descent and not by
ascent. He was right in that to some extent, but that theory
did not cover the whole question. But he (the lecturer) was sorry
that Dr. Murray had made such a bold statement as that there
was no evidence of subsidence. Well, he would show them that
night that even such great men as Dr. Murray and Dr. Guppy were
wrong, and that Darwin was right about the Great Barrier Reef of
Australia and the Fiji Islands. But Darwin was not right in
making his theory account for all corals and coral islands, because
there were ascending islands.
In taking up the study of coral, one had to unlearn something
which had been learned at school. For instance coral was not an
insect, nor did it live deep down in the sea as we were taught as
children : —
“ Deep down the silent ocean
Dwells the coral insect rare.”
It was one of the jelly-fish family, and first cousin to the well-
known sea anemone. It did not live deep down in the ocean, and
that was a problem that Darwin had to solve. The coral animal
could not live in water of lower temperature than 60° F. — that was
to say, the animals most prolific in building up reefs. It required
a temperature of 60° F., but near England and along the coast of
Portugal there was only a temperature of 50° F. or thereabouts.
Coral in these two places was making no headway. There were
miles and miles along the coast of Portugal where there were
immense forests of branch coral, but which was not forming reefs
or coral structures of any kind but simply breaking up and being
destroyed. Seeing that coral requires a warm temperature, it
showed that England once enjoyed a hot climate, because we have
plenty of evidence of coral reefs.
Proceeding to his lecture proper, Mr. Swainson first exhibited
specimens of branch coral, and explained that the ends of this
broke off and formed a substance like snuff. When the tide went
down and this was exposed to the sun, it became solid and formed
a hard durable substance like cement, and layer upon layer of this
accumulating, so coral reefs and banks developed.
96
PHARMACEUTICAL JOURNAL.
[JAN. 30„ 1897
Darwin’s theory for this formation was slow descent of the land
with the coral building upwards, but Mr. Murray declared for the
ascent of the land. Having thus prepared his hearers for the two
issues, Mr. Swainson proceeded to exhibit a long succession of re¬
markably fine microscopic and photographic slides showing all
sorts of coral and anemones, all the while explaining the growths,
and keeping in mind the two points he wished to elucidate for the
benefit of his hearers. He showed that in many instances islands
and lands in the vicinity of which coral existed had gradually sub¬
sided into the ocean. Simultaneous with this subsidence the coral
animal had been building up their structure, and finally their reef or
island marked the point at which the last peak or summit of the
submerged land has disappeared.
By this system of reasoning it was shown that Australia had
once been vastly in excess of its present size, while the Fiji and other
islands were similar instances. Thus by the formation of the
cement of which the banks and the islands were composed, and the
building up of the barrier reefs, the two theories of Darwin and
Murray were each proved to be correct. Incidental to this ex¬
planation, however, were views and statements showing the birth
and development of the coral, from which it was gathered that
eggs from which the minute creatures sprung were at the appointed
time cast off into the sea by the parent animal and the young swam
about until it found some object to cling to. Great numbers of
the animals adhered to each other and formed one substance, while
at the same time each was a separate and distinct organism.
The method of obtaining food was explained, and it was further
shown that with the advance of time, the nourishment obtained
formed line, and the various corals became welded together, so to
speak, inseparably, though between each there was a system of
communication by means of which nourishment could be conveyed
throughout the whole of the little community, from the one to the
other. Like the anemone, coral had power of defence by
means of stinging. A large number of specimens of coral were
shown, and their peculiarities explained, and Mr. Swainson con¬
cluded his most fascinating lecture with the following appropriate
lines from the pen of Sheffield’s own poet — Montgomery.
“ Line laid on line, on terrace terrace spread,
To swell the heightening, brightening, gradual mound.
By marvellous structure climbing towards the day.
Each wrought alone, yet altogether wrought,
Unconscious, not unworthy instruments
By which a Hand invisible was rearing
A new creation in the secret deep.”
Pharmaceutical Chemists’ and Apothecaries’ Assist¬
ants’ Association of Ireland, Friday, January 22. — Mr. W.
Vincent Johnston in the chair. — Mr. W. U. Smith read a paper on
Sulphuric Acid and its Manufacture.
He gave a general outline of the process of manufacture, and
explained in a lucid manner the different appliances used therein.
The gases S02 and nitrogen oxides are generated and conducted
together into a large leaden chamber, the S02 combined with an
atom of oxygen taken from oxides becoming S03, and this in turn,
when it reaches the chamber combines with the vapour of water
which is being injected, and becomes H2S04, which condensed on
the surface of the chamber. The acid, which is of a strength
between 1 '5 and 1 -6, is then concentrated, and purified from nitrous
gases by passing it through a series of Gay Lussac and Glover towers,
and then further concentrated and purified, the process being a
continuous one. The gases pass in a constant stream into the
chamber, there becoming combined with the aqueous vapour
introduced in the form of steam, the resulting acid collecting on
the floor of the chamber. The nitrogen oxides generated are the
higher oxides, and on being deprived of an atom of 0 by the S02
immediately replace the lost 0 from the air, so that theoretically
the supply of N20:j would act as a carrier of O for an indefinite
amount of S02. Practically this is not so, and the Na03 has to be
supplied in a constant stream along with the other gases. The
source of the S02 is either sulphur itself or iron pyrites which
contain from 30 to 50 per cent, of sulphur ; iron pyrites is chiefly
used in this country. The lecturer exhibited different specimens
of pyrites, some of which were stated to be much richer in sulphur
than others. When pure acid is required sulphur must be used,
as pyrites almost invariably contained arsenic. The source of the
nitrogen oxides is nitrate of soda, and the source of the steam is
an ordinary steam boiler of 20 h.p.
Liverpool Pharmaceutical Students’ Society, Thurs¬
day, January 21. — Mr. John Jones, President, in the chair. — An
illegible prescription was passed round for the members’ inspection
by Mr. Morgan for Mr. Cowley, and subsequently Mr. Charles
Larkin, F.R.C.S., lectured upon
Digestion.
After a description of the anatomy of the digestive organs, with
particular mention of the mouth and throat, the lecturer explained
the structure and uses of the secretory glands covering the surface
of the tongue, stomach, duodenum, and bowels. The salivary
glands and. their secretion of an amylolitic ferment, ptyalin, the
glands of the stomach and their pepsin, and the glands of the pan¬
creas with their pancreatine, were all shown to be necessary to perfect
digestion, and the substances in our daily food acted upon by these
several active principles were touched upon, and the differences in
nutritive value between the peptones produced by the digestion of
albumins and fibrin, and those from gelatinous bodies emphasised.
The anatomical portion of the lecture was illustrated by excellent
lantern slides from drawings and diagrams made by the lecturer,
who exhibited numerous similar slides made from microscopical
preparations, all of a high degree of merit. At the termination of
the lecture, which was listened to by a very appreciative if some¬
what small audience, a hearty vote of thanks was accorded to
Mr. Larkin on the proposal of Mr. R. H. Mitchell, seconded by
Mr. T. S. Wokes.
Glasgow Pharmaceutical Association, Thursday,
January 21. — Mr. W. L. Currie, President, in the chair. — Mr.
J. H. Hoseason, of the Glasgow School of Pharmacy, read a
paper on —
Alkaloids.
He gave a short historical account of the alkaloids, beginning
with the discovery of morphine by Sertiirner in 1804, his recog¬
nition of its basic properties and its probable relationship to
ammonia. Liebig’s prediction of the organic ammonias and the
syntheses of these by Wurtz and Hofman at a later period were
dealt with. Mr. Hoseason then showed the relationship existing
between ammonia and primary, secondary, and tertiary mona¬
mines, including the various methyl and ethyl derivatives of these,
and afterwards the bases contained in bone oil and coal tar, namely,
pyridine, picolines, lutidenes, collidenes, etc. , quinoline, isoquino¬
line and acridene. The constitutional formulae of some of the
principal diamines, triamines, and tetramines were next discussed.
The saponification of piperine and the methods for determining
the products of decomposition by ultimate analysis, fusion
with potash, further oxidation and comparison of the substances
so obtained with similar known bodies was fully described. The'
synthesis of any alkaloid from artificial products was the best proof
of the correctness of our experimental data and deductions. Deal¬
ing with the study of the pyridine carboyl compounds the lecturer
showed the great value the knowledge of these had been to the
organic chemist in elucidating the structure of various alkaloids
Mr. Hoseason concluded by giving brief descriptions of the
methods employed in isolating and identifying alkaloids, illus
trating his remarks by a few experiments. Messrs. T. and H.
Smith, of Edinburgh, kindly sent a large selection of the rarer
alkaloids for exhibition, and the opportunity of examining these
was greatly appreciated by the members of the Association whe
were present.
Bradford and District Chemists’ Association, Tues¬
day, January 19. — Mr. A. H. Waddington in the chair. — A
lecture on — -
Bacteriology
was given by Mr. F. W. Richardson, F.C.S., F.R.M.S., etc., a-
gentleman well known in the district as an expert in that science.
The lecture was illustrated by sixty-six specially prepared slides
admirably exhibited by Messrs. Riley Bros.’ powerful lantern.
There were also in evidence a large number of pure crdtivations of
microbes on different media in large test-tubes, with several
accessories for bacter iological work. Clear illustrations were given
of the methods of distinguishing between the various kinds of
microbes by means of their peculiar and distinctive affinities for
certain foods and temperature^ and their characteristic growths on
different media. All the chief disease germs were optically de¬
picted, and the bacterium assumed to be the cause of pubonic plague,
“ Black Death,” etc., received rather full attention, as this microbe
Jan. 30, 1897]
PHARMACEUTICAL JOURNAL
9 7
is of peculiar and melancholy interest at the present time. In
conclusion there ensued a brief summary of industrial bacteriology ;
.a subject in itself requiring several lectures for adequate eluci¬
dation. It was pleasant to learn that of microbes there are ‘ £ more
that be for us than against us,” and that to them we may look in
the future for the solution of a number of hitherto insoluble
technological problems.
Bristol Pharmaceutical Association, Wednesday,
January 27. — Mr. B. Allen, President, in the chair. — The annual
meeting of this Association was held at University College. The
Treasurer’s report, showing a balance in hand, was read by Mr.
.Stroud. The Hon. Secretary, Mr. Keen, read the following
report of the Council for the year 1896 : —
“The Council cannot report a year of any great activity, yet they think some
useful work has been done in the way of arousing an interest in the Association
amongst members of the trade. Early in the year a meeting was held for the
purpose of discussing the proposals made by the then newly-formed P.A.T.A.
There was a large and representative gathering, by which a resolution was unani¬
mously passed, that it was desirable to support that Association. A resolution
upon that subject will also be submitted to you to-night. In the autumn the subject
■of winter evening classes for students was considered by the Council. Consider¬
ing that the materia medica class had been carried on for two consecutive winters,
it was thought best to suspend that class for one year and to call attention to the
other scientific subjects so well arranged for at University College. A prospectus
of the College was sent by this Association to all chemists in Bristol and neigh¬
bouring towns. The Council are glad to know that at least eight students, who
.are either assistants or apprentices with local chemists are now' working at the
College. In the early part of the year we lost one of our oldest supporters in the
-death of Mr. La Trobe. In the spring our old friend and colleague Mr. George
F. Schacht intimated his intention of withdrawing from the Council of the
Pharmaceutical Society. The Council of this Association thought it desirable in
some way to mark its sense of obligation to Mr. Schacht for his long period of
service, as well as to express to him its high appreciation of his personal character.
It was determined therefore to ask Mr. Schaclit’s friends to unite in presenting
him with an illuminated address. The presentation was duly made in August.
Although our friend had passed the allotted three score years and ten, he seemed
in good health and spirits. We looked forward with hopefulness to his help for
many years. But before the year had ended we stood at his grave regretting the
doss of a true friend, an accomplished pharmacist, and a loyal citizen.”
The President moved the adoption of both reports, which were
.agreed to unanimously. The following were elected as officers for
the ensuing year : — President, Mr. B. Allen ; Treasurer, Mr. J.
Stroud; Hon. Secretary, Mr. B. Keen; Council, Messrs. Buxton,
W. Berry, Chandler, Plumley, Pitchford, Turner, Young, Warren,
White. The following resolutions were then unanimously passed
by the meeting : —
Resolved —
“ That this Association desires, at its first meeting after the event, to express
its deep regret at the death of our colleague Mr. Geo. Fred. Schacht, whose
interest was so long experienced in its aSairs. This Association remembers
with gratitude the variety of ways in which Mr. Schacht promoted its
interests, his unfailing courtesy, his wise counsels, as well as his high per¬
sonal character, and desires to assure Mrs. Schacht and her family of their
sincere sympathy in their great bereavement.”
Resolved —
“ That this Association desires to express its satisfaction of the measure of success
achieved by the P.A.T.A. during the first year of its existence, and resolves
to continue its support to the Association. It also urges the retail chemists
of the country to join the P.A.T.A. in larger numbers, as being the most
practical way of limiting the extreme cutting prices.”
Resolved —
“That this Association deeply' regrets the position assumed by the C. A.
Vogeler Co. in their correspondence with the Bradford Chemists’ Association,
and hereby protests against members of their craft being called ‘un¬
principled ’ because they refuse to deal in any particular proprietary article,
whether it bears a profit or not. If the C. A. Vogeler Co. wish their prepara¬
tions to be distributed by chemists, this Association recommends them to
put the articles on the P.A.T.A. list."
It was further resolved that in future a quarterly meeting of
the Association should be held, also that it is desirable at some
convenient and early date a dinner should be arranged for.
SOCIAL MEETINGS-
Midland Pharmaceutical Association, Thursday, Jan¬
uary 21. — The twenty -fourth annual ball was held in the Grosvenor
Rooms at the Grand Hotel, and proved a great success. The
handsome rooms had been prettily decorated for the occasion, and
as this is one of the popular functions of the local dancing season,
the event was largely and influentially patronised. The President
(Mr. J. F. Gibson, Wolverhampton) attended with a party of
guests, and among the numerous company present were Pro¬
fessor and Mrs. Hillhouse (Mason College), Councillor Barrett
and party (Leamington), Councillor and Mrs. Price,
Dr. Kneale, Messrs. F. H. Alcock, A. Blackburn, T. W.
Chapman, F. Barlow, J. Wakefield, C. S. Baynton, R.
Brown, S. L. Bates, W. T. Elliott, H. M. Bindloss (Midland
Chemists’ Assistants’ Association), etc. Mr. A. Gregory’s band
supplied the music, and the duties of M.C. were discharged by
Mr. E. J. Reynolds. The general arrangements were admirably
carried out by Mr. Charles Thompson and Mr. J. C. Mackenzie.
Dancing was kept up till two o’clock.
Edinburgh District Chemists’ Trade Association,
Thursday, 21st inst. — The fourteenth annual ball took place in the
Freemasons’ Hall, George Street. About eighty couples were
present, and a very pleasant evening was spent to the music of
Mr. Craig Lumden’s band. The duties of M.C. were efficiently
discharged by Messrs. Butchart and Jardine, and an excellent
supper was purveyed by Mr. Sawers. All the arrangements were
admirably carried out under the direction of Mr. R. I. Macdougall,
convener of the Committee.
PARLIAMENTARY NOTES AND NEWS-
The Committee of Inquiry on petroleum is to be reconsti¬
tuted at an early date. Though the Committee took a large
amount of evidence, chiefly scientific, last session, its work is by
no means completed. The vexed question of construction of
lamps, and the commercial considerations involved in amending
the present regulations as to storage of the oil, will necessitate the
examination of a number of witnesses yet. If it be found impos¬
sible to report finally on the subject during the Session, public regret
will be tempered by the feeling that, at any rate, when legislation
does come it may be expected to be thorough.
The Royal Commission on Tuberculosis has resumed its
meetings and is taking evidence three days a week, under the
chairmanship of Sir Herbert Maxwell, M.P. The witnesses are
for the most part medical officers to Metropolitan Boards, or to
large Provincial Boroughs, and Inspectors of meat to various local
Health Authorities.
First Readings of a multitude of private members’ measures
took place on the 22nd inst. Among the host, may be noted
several which have seen more than one session, and it is sad
to think that some will also have to reappear at future
sessions if they are to be enacted. The subject-matter of these
Bills covers a very wide range and seems devised to advance every
department of human activity but pharmacy, and to benefit every
class of worker but the chemist. The “ Deceased Wife’s Sister”
— that doyen — of Bills — makes its reappearance under the segis
of Mr. Spicer. Education is represented by Sir A. Forwood’s
Bill to permit School Boards to assist Voluntary schools out
of the local rates, and by a Bill to amend the Education Acts of
1870 and 1871 (Sydney Gedge). Sir J. Lubbock and Sir C. Dilke
take up the cause of the shop assistant, the former with his now
familiar Shops (Early Closing) Bill, and the latter with a “ Bill to
amend the law relating to Shops.” Other measures of passing
note are those dealing with the registration and inspection of
boilers, the registration of plumbers (which, by the way, is en¬
dorsed by Dr. Farquharson), the suppression of street noises, old
age pensions, and the simplification of registration for parlia¬
mentary voting. In face of the rumours that the Government
will early take Wednesdays for its own business, there seems
little hope for a large portion of the foregoing.
Sale op Food and Drugs. — A Bill to consolidate and amend
the law relating to the Sale of Food and Drugs has been introduced
by Mr. Kearley, and is supported by Sir James Wodehouse, Mr.
Horace Plunket, Mr. Lambert, Mr. Jeffreys, Mr. Nicol, Mr.
Channing, and Mr. Maurice Healey. Second reading is fixed for
Thursday, March 18.
The Vaccination Question gives promise of maintaining its
position as a favourite pretext for minister-baiting. The Session is
little more than a week old, and already the question paper bears
several cunningly-worded queries intended to draw official replies
favourable to the particular opinions of the interrogator, or those
for whom he acts. Mr. Logan, who was sent to St. Stephens by a
somewhat decided anti-vaccination constituency (Leicester), has
been first in the field by asking the President of the Local Govern¬
ment Board whether the Government intends to carry out the
98
PHARMACEUTICAL JOURNAL.
[Jan. 30, 1897 1
recommendations of the Royal Commission (for a precis of which
see Pharmaceutical Journal, Aug. 22, p. 173). In the absence of the
President of the Department, Mr. T. W. Russell, the Parliamentary
Secretary, stated that' the report of the Commission was receiving
the consideration of the Local Government Board. It was, how¬
ever, the duty of Boards of Guardians to enforce the existing law,
and the Report did not in any way relieve them from that duty.
“What is the existing law?” asked Mr. Lough (W. Islington) ; and
“Would it not be advisable to alter the law in conformity with the
Commissioners’ Report ?” added Mr. Logan. But on both these
points Mr. Russell was diplomatically dumb.
Ministry of Public Health. — Commenting on the increasing
pressure of departmental duties at the Local Government Board,
we recently hinted at the possibility of advantage resulting from
the constitution of a Department of Public Health {Ph. J., Dec. 19,
p. 534). The same idea seems to have occurred to Mr. Fortes cue
Flannery (Shipley), who has now recorded his intention of moving
at the earliest opportunity that “it is desirable that a Depart¬
ment of Public Health be constituted, and that the same be under
the charge of a responsible minister having a seat in Parliament.”
The Early-Closing Bill has now . been circulated and is
pi’actically identical with the measure which passed through Grand
Committee last Session. The saving clause for pharmaceutical
chemists, chemists and druggists, and registered druggists is
retained. The second reading of the Bill was in the first place
ut down for Monday 25, then for the following day, and has now
een relegated to February 1. Three unsympathetic legislators
have placed “blocking” notices in the way of the Bill, viz., Mr.
R. G. Webster, Mr. Duncombe, and Major Dalbiac.
Food Products Adulteration. — Mr. Kearley duly moved the
amendment to the Address standing in his name. Mr. Jeffreys
(Basingstoke), in seconding the motion, submitted that British pro¬
ducers were unfairly hampered by the admission of adulterated
and, consequently, lower-priced imports. The motion also had
the high support of Mr. Maurice Healy, who complained especially
of adulterated butter. Replying on the debate, Mr. T. W.
Russell pointed out that the Report of the Select Committee
on Food Products had practically only just been received, and
immediate legislation could hardly be looked for. A Bill dealing
with the subject would be no doubt contentious, and there would
be great difficulty in fixing a standard of purity. A draft Bill had
been prepared, but he thought it improbable that it could be intro¬
duced this Session. Sir W. Foster thought, and many professional
men may be found who hold similar opinions, that the difficulties
as to standard were exaggerated. He hoped for an early introduc¬
tion of the Bill. Mr. Balfour, however, considered that the
Government ought not to be asked to make a pledge. And thus
the amendment fell, with the assertion of Mr. Lough, by way of
benediction, that the worst adulteration was done in this country.
PUBLICATIONS RECEIVED.
Our Weights and Measures. By H. J. Chaney. Pp. 157,
illustrated. Price 7s. 6 d. London : Eyre and Spottiswoode,
East Harding Street, E.C. 1897. From the Publishers.
A Simple Method of Water Analysis. By John C. Thresh,
M.D., etc. Pp. 47. Price 2s. 6 d. London : J. and A. Churchill,
7, Great Marlborough Street. 1897. From the Publishers.
Jahresbericht uber die Fortschritte der Chemie und ver-
wandter Theile anderer Wissenschaften. Begriindet von
J. Liebig und H. Kopp. Herausgegeben von F. Fittica.
Fur 1890. Braunschweig : Druck und Yerlag von Friedrich
Vieweg und Sohn. 1896. From the Publishers
The Botanist’s Pocket Book. By W. R. Hayward. Pp. 226.
Price 4s. 6d. London : George Bell and Son. 1896. From the
Publishers.
The Natural and Artificial Methods of Feeding Infants and
Young Children. By Edmund Cantley, M.D. (Cantab). Pp.
376. Price 7s. 6 d. London : J. and A. Churchill, 7, Great
Marlborough Street, W. 1897. From the Publishers.
Dental Surgery for Medical Practitioners and Students of
Medicine. By A. W. Barrett, M.B. (Lond.), M.R.C.S.,
L.D.S.E. Pp. 154. Price 3s. 6 d. London : H. K. Lewis, 136,
Gower Street, W.C. 1897. From the Publisher.
CORRESPONDENCE.
All Articles, Letters, Hotlcea, and Reports Intended for
publication In the Journal, Books for Review, and com¬
munications respecting Editorial matters generally,,
must, be Addressed “Editor, 17, Bloomsbury Square,
London,’’ and not in any case to individuals supposed
to be connected with the Editorial Staff. Communica¬
tions for the Current Week’s Journal should reach the
Office not later than Wednesday, but news can be Re¬
ceived by Telegraph until 4 p.m. on Thursday.
Correspondents who wish notice to be taken of their communications must
write in ink, on one side of the paper only, and should authenticate the.
matter sent with their names and addresses — of course not necessarily for
publication. No notice can be taken of anonymous communications.
Names and Formula: should be written with extra care, all systematic names
of plants and animals being underlined, and capital letters used to commence
generic but not specific names.
Any Instructions from Members, Associates, and Students of the Pharmaceutical
Society, with reference to the transmission of the Journal, should be sent to
the Secretary — Mr. Richard Bremridge, — 17, Bloomsbury Square, London.
Business communications — including advertisements, orders for copies of the
Journal, and instructions from Subscribers respecting transmission of
same — must be addressed to the Publishers, 5, Serle Street, Lincoln’s Inn,
London. Cheques and money orders should be made payable to “Street
Brothers.”
Drawings for illustrations should be executed twice the desired size ; clean,
sharp lines being drawn with a pen and liquid Chinese ink. Shading by
washes is inadmissible. Photographs can be utilised in certain cases.
Reprints of articles cannot be supplied unless authors communicate with
the Editor before publication.
An Appeal.
Sir, — The “ Diamond Jubilee” of Her Most Gracious Majesty’s
reign is likely to be a historic year in the annals of charities.
Throughout the world loyal subjects of our beloved sovereign are-
considering the most fitting way of marking their appreciation of
all the blessings which have attended her long and beneficent'
reign, and we have the assurance of H.R.H. The Prince of Wales-
that no form will be more pleasing to Her Majesty than those
having for their object the alleviation of human suffering and
distress. May I then most respectfully suggest that we who are
engaged in the calling of pharmacy make it a memorable year in
connection with our Benevolent Fund. A most deserving cause,,
and, unlike many other charities, bestowing a maximum of help at
a minimum of cost to the Fund. Let us make one grand united
effort to put it into a sound position, such as it has. not hitherto
known, and thereby enable the distributors of the Fund to dispense
more relief to the distressed and add some scrap of comfort to the
lives of our less fortunate, though not necessarily less deserving
brothers and sisters.
The plan I would propose is (1) that each present subscriber
double his subscription for this year ; (2) that every chemist or
chemist’s assistant not already a subscriber be personally invited
to become one, and (3) that an organised plan of campaign be
arranged to cover the whole of Britain. In many districts,
the local secretary will be all sufficient for the purpose ; in-
others he may probably succeed better if supported by a
second, whilst in others it may be necessary to accomplish the
work in a reasonable time (owing to the large area of the local
secretary’s jurisdiction) that he has a fair number of coadjutors,
and that these should again be divided to work in pairs. In sparsely
peopled districts and outside the reasonable limits of a secretary’s
working area representatives of wholesale drug firms might be
asked, and would, I feel sure, be found willing to render this small
service ; and to this end a few of the principals of the leading-
firms might be invited to co-operate and nominate one or more of
their “ commercials ” for particular localities. It should not be a
difficult matter to arrange the ground, and if you, sir, or our
estimable secretary would convene a meeting at the Society’s
rooms or at some central place in London, it might, so far as
England and Wales are concerned, soon be un fait accompli.
Our Scottish brethren who work the North British territory
might be similarly marshalled by our genial friend Mr. Rutherford
Hill, and thus the chemist in the far-off village or secluded hamlet,
would be reached and afforded an opportunity of joining in this
grand work of charity. Will the local secretaries throughout the
country see to their portion of the work ? Will volunteers offer
themselves in this and other large centres, so that the work may¬
be apportioned and begun? And will everyone who reads this
Jan. 30, 1897]
PHARMACEUTICAL JOURNAL.
99
appeal take it as a direct personal one, and, whilst being grateful
for the peace and general prosperity which have marked our good
Queen’s reign, be thankful for the opportunity of showing his
gratefulness in a practical sympathy with those who have fallen
upon hard times ?
January 23, 1897. Harry Kemp,
Local Secretary for Manchester.
The Journal and its Students’ Page.
Sir,— “ The Students’ Page ” is undoubtedly a capital addition
to the Journal. Might I suggest a similar page being devoted to
the encouragement of Major students ? I think you will agree with
me, sir, that there are many newly-fledged “Minor ” men who would
continue their studies for the Major examination if it were not for
further considerable expense, and a loss of quite six or nine months’
time from business. Further, the advantages derived from the
possession of this additional qualification in our present time, in
the opinion of we young “ Minor ” men — whatever our older friends
might say — does not encourage us to spend so much more time and
more money to get it. It seems to me that plenty of careful
reading is needed for the Major examination, and the majority of
young qualified men of the present day having had a systematic
course of tuition for the Minor, with a few hints on the various
“ Major ” subjects, some guidance as to what is expected would
enable them to master almost, if not quite, all the theoretical
studies after business hours or at home. After allowing this
method of study to extend over some twelve or eighteen months,
I believe three months’ practical work under a good tutor would
enable the average “ Minor ” man to pass the “Major.” This I
believe would be a practical step towards increasing not only the
number of Associates of the Society, but also multiply the number
of candidates for the Major examination. Though only a “Minor”
myself, I realise that it is the “ Major ” men who chiefly keep the
Society more closely together, because having continued their
studies after merely qualifying, interest in the Society continues
as a result, so that only in a few cases does that interest, once
. having got a firm hold, dwindle away, as is the evident case with
so many “Minor” men who lose all interest in the Society very
soon after qualifying. It is useless trying to draw old sheep into
the fold — try your hand at we youngsters by the plan I have here
suggested and note the result.
Weymouth, January 18, 1897. Qualified (77/17).
Sir, — In common with the majority of the members of the
Society, I have been greatly pleased with the recent alteration and
development of the Pharmaceutical Journal. Surely no young
apprentice or student can now say that he finds nothing in the
weekly issue to interest him. Nor can the busy pharmacist com¬
plain that the same number contains no business matter. To
cater for all sorts and conditions of active pharmaceutical life and
still retain the premier place in the domain of scientific literature
is a heavy task to attempt. You seem, however, to have a happy
way of mastering difficulties, and I heartily congratulate you upon
the success which you have already achieved.
Shrewsbury, January 23, 1897. <t. W. Gowen Cross.
Sir, — Having read the Pharmaceutical Journal now for over
twenty years, I am able to appreciate the efforts to make it a
really representative Trade Journal. “ The Students’ Page ” is a
great addition.
Honiton, January 21, 1897. E. H. Dyer.
The Regulation of Prices.
- Sir, — Mr. Snook’s letter which you published in last week’s
Journal covers nearly all the ground, but I should like to empha¬
sise one point, viz. , that it is to the interest of all manufacturers
to enlist the active and friendly co-operation of all who retail their
goods. . As the cheapest method of increasing their sales, costly
advertising is all very well, but most of it is quite unnecessary,
and merely means the senseless giving away of profits. Old time
retail profits are a thing of the past ; all we want is a reasonable
living profit in return for our help in stocking and sell¬
ing articles which at best cannot be very remunerative,
and an end put to the present unsatisfactory state of things
which upsets public confidence all round. I should like, also, to
point out the help derived from catering for drug stores is of more
than doubtful benefit. ( 1 ) Because drug stores invariably run articles
as much as possible like those they sell (as rarely as possible) at
store prices ; (2) because they are anybody’s friend, and ready,
for a consideration, to fill their window and boom A’s baby’s food
to-day and do the same for B’s food next week and C’s food the
week after, all the while pushing their own food at the expense of
all three. Makers of proprietaries should note, too, they lack an
element of stability, which may some day prove their ruin. There
are journals now in existence which sell cigarettes. Why not
pills ? And where will the pattent medicine proprietors be when
their advertisements are neither asked for nor wanted. They will
be in the unenviable position of not having a friend in the world.
Said a German to me the other day, “ Such a state of things as
you describe would be impossible in Germany, because no one
would be such a fool there as to trade without a profit.” I am glad
to think common-sense is beginning to assert itself over here.
January 26, 1897. Honest Trader (78/10).
Sir,; — Although outsiders like myself may read with interest the
reports of the doings of the P.A.T.A., may admire its tenacity of
purpose and the unity which has already caused its power to be
felt, yet many, no doubt, like myself, seek in vain to learn and be
convinced of the practical utility of what has been accomplished
and what is to be accomplished in the future. Suppose that all
the proprietors of patent medicines of note consent to put their
articles on the protected list, with a uniform retail selling price,
what is the position then ; viz. , that articles which have hitherto
been bought by the cutting trader at 10s. per dozen and sold
at 10 \d. each are now bought by him at 11s. 6 <7. dozen and
sold at Is. 1 \d. each, still leaving in his hands a branch
of business which yields a very large return, is no trouble
to handle, and forces him to take a gross profit of some
15 per cent. True, they have been deprived of a very great
draw, but then there is nothing original in using this means in the
retail trade to obtain customers; it is done, and has been for
years, by drapers and grocers, and in every trade where competi¬
tion is very keen. Are we to think because we have deprived
them of this method of advertising and yet left in their hands a
largely increased profit that there is no other way open to them ?
It has been suggested that chemists foster some special proprietary
of their own, and by company trading find the means to advertise
it and push the sale, but this way is also open to any of the large
drug stores, which are in the hands of business men with plenty
of capital behind them, who could develop many specialties and
advertise them in a way that would be impossible to chemists
acting either singly or in concert. Suppose when the stores are
deprived of the patent medicine draw they turn round and
commence universal cutting in drugs, for if you look through the
lists of the large cutting stores you will find many articles in
common demand that would still bear a considerable reduction in
price, and for which if the public were simply charged a bare trade
profit, the demands of the chemist might be made to appear far
more exorbitant than the 3d. in the Is. obtained for patents. The
line of action which would bring about such a result seems to me
to savour largely of putting us out of the frying-pan into the fire.
Side by side with this outcry to stem the torrent of bad times upon
which the chemist has fallen comes the optimistic little leader in
the Journal on “ The Trade in Proprietary Articles,” in which we
are assured that although the number of chemists is greater, yet
on the average they are almost certainly better off than their pre¬
decessors of some fifteen or sixteen years ago, whilst “how much
more so he (the average chemist and druggist) maybe rests largely
with himself to decide.” Are chemists then generally doing well),
but continuing to grumble to prevent it being found out?
Coleford, January 26, 1897. F. H. Scutham.
Chemists’ Federation.
Sir, — Mr. Cooper is quite right in his assumption that I am in
favour of some such scheme as propounded by Mr. Foulston, and I
think it is a subject that might with advantage be discussed by local
associations at present, with a view to future action if necessary,
and found practicable. At present I would suggest that retail
chemists should concentrate their efforts at making the present
trade movement (P.A.T.A. ) a success, by joining and inducing
others to join.
They would then be able to form an opinion as to who were
willing amongst the proprietors to try and safeguard retail
interests, and who were indifferent. The retail trade must have
a little more patience, or else bestir itself more in its own interests.
[Jan. 30, 1897
H'O "PHARMACEUTICAL JOURNAL.
It cannot expect proprietors who have invested many thousands of
pounds in advertising their preparations to join any scheme
without full consideration, and until they have come to the con¬
clusion that it is to their own interests* as well as to the interests
of the retailers. It is very encouraging to see what successful
meetings in support of the P. A. T. A. have been held in the North,
and the action of so shrewd and successful a business man as Mr.
Snook should attract new members to the retail section, and
encourage proprietors to take the same step.
Plymouth, January 25, 1897. Charles J. Park.
The Minor Examination Syllabus.
Sir, —On page 72 of last week’s journal, in some annotations on
the Minor examination syllabus, you refer to a feeling among
students that the examiners require more than is stated in the
syllabus from a candidate. You advise students to reject this
idea, and to “give the examiners credit,” etc. But, sir, there are
scores of students who have passed the examination, as well as
many who have failed, who could tell you of many a question
asked quite unprovided for by the published syllabus.
It is some years now since I was plucked at the Pharmacy table
by an examiner, who was the essence of kindness and politeness to
his candidates, but who “regretted that he could not pass” me
unless I could write out all the ingredients of three compound tinc¬
tures. Five out of six I gave, but a nervous memory refused to re¬
call the sixth, and I was rejected. Again, in a very recent examina¬
tion I know a candidate who was closely questioned in the
chemistry room on crystallography. He admitted to the ex¬
aminer that he had not studied the subject “as it is not men¬
tioned in the syllabus,” and was met with this reply — “I know it
isn’t, but you can’t study chemistry or pharmacy without it,
because the Pharmacopoeia describes certain substances as
crystallising in certain definite forms.” I do not say that the can¬
didate was ‘ ‘ ploughed ” on crystallography, but I believe that his
failure was due in no small measure to his being confused and
frightened by the introduction of that subject.
The examiners may be all that you say that they are, sir, and I
never yet met any student, successful or otherwise, who could say
that he had found them other than thorough gentlemen in their
manner of dealing with candidates, but there are more than one or
two grave faults to be found with the method of the examination,
and you would confer a very great boon on the future candidates
if you would open your columns to a free discussion of the
grievances w hich do, or are alleged to exist in connection with the
Minor.
January 21/., 1897. Audi Alteram Partem (77/33).
*** Space is found for the above letter because it is always desirable that the
baselessness of imaginary grievances should be exposed whenever possible.
The question which our correspondent alleges was the cause of his discom¬
fiture in the examination room seems to us an eminently proper one, as
candidates ought certainly to know what ingredients- are contained in all
official preparations. This is quite a different matter to being able to state
off-hand the “proportion” of- all the ingredients in any preparation. It is
extremely doubtful, too, whether rejection was due to failure to answer this
one question. . The probability is that this was merely the culminating point
m an exhibition of decided weakness in Pharmacy. The other instance
adduced is quite beside the question, for assuming the accuracy of the state¬
ment that the candidate was “closely” questioned on crystallography, there
is no evidence that his interests suffered because of his ignorance of the
subject, whilst ability to answer the supposed questions would have been
very much to his credit.— [Ed., Eh. /.]
A Correction.
Sir, — I must ask you to allow me to point out that the report
given in the Pharmaceutical Journal of January 23, of my remarks
P^A.T.A. meeting in Newcastle, is not quite correct. If it is so
altered as to read “proprietary articles” instead of “drug” or
“drugs,” it may be intelligible. This, together with “previous
good behaviour ” may excuse me in the eyes of lenient friends.
Newcastle-on- Tyne, January 25, 1897. " T. Maltby Clague.
A Panegyric.
Sir, — I was surprised to see your answer to Associate (75/9) in
the Journal of January 16, re boroglyceride, as the present
generation of pharmacists are more indebted to Mr. Martindale
for the information published in the Extra Pharmacopoeia than to
any other living pharmacist. When reading the answer, I thought
you had vacated the editorial chair for a stool in the research
laboratory, and that you were busy on aconitine original notes
“ Made in Germany.” It has not surprised me that Mr. Martindale
should “feel hurt” by such remarks.
- London, January 26, 1897. John Hick.
ANSWERS TO QUERIES.
[Queries addressed to the “ Editorial Department, 17, Bloomsbury Square, W.C.,"
will be replied to in the Journal as early as possible after receipt, but the Editor
cannot undertake to reply to them through the post, nor is it always possible to publish-
answers the same week. Questions on different subjects should be written on separate
slips of paper, each of which should bear the sender’s name or initials. Readers
requiring working fornlula? for special preparations, and intimating their wants to the
Editor, will be assisted as far as may be practicable. The word “parts," when used in
formula, invariably indicates parts by weight. Anonymous queries will be ignored .]
Specimen Identified. — They are the seeds of Butea frondosa,
which are used as a vermifuge. [Reply to T. H. I). — 77/9.]
Woven Asbestos Fabric. — You will probably get what you
require from Bell’s Asbestos Company, 59§, Southwark Street,
S.E. [Reply to J. W.— 76/23.]
Starch Gloss. — Powdered borax, 3 ounces ; paraffin wax, 2
drachms ; dextrin, f- ounce ; potato starch, 6^ ounces. Melt the
paraffin and pour it upon the mixed powders in a mortar. Bub
well till a uniform mixture results. [Reply to H20. — 77/7-]
Butyric Fermentation. — You will probably succeed with the
fermentation process you mention if you give it time enough.
Patience is essential to success in this experiment. The best
cheese for starting the process is thoroughly rotten cheddar, mixed
with an equal weight of very rancid butter. [Reply to H. R. — 77/18. ]
To Turn Dark Hair Yellow. — The only satisfactory body for
this purpose is hydrogen peroxide. First free the hair from any
greasy secretion by washing in water containing a little ammonia.
Dry well, and apply the peroxide freely. In course of time tlie
hair will be bleached to almost any degree of yellow you require.
The peroxide is perfectly harmless. [Reply to Lac. — 76/40.]
Maggots in Canary Seed. — Put a few pieces of naphthalin in a
piece of muslin in a tight-fitting tin box (a 100-ounce quinine tin
or a biscuit box), pour the seed upon it, close up the lid, and let
it stand in a moderately warm place for a few days. Then spread
out the seed to the air until every trace of the smell of napthalin
has gone. It' is soon volatilised. This is an excellent remedy for
maggots and also for “ moth ” in clothes. [Reply to M. P. S. — 77/10.]
Handbook of General Analysis. — You will probably find
Pearmain and Moor’s ‘Aids to the Analysis of Foods and Drugs,’
published by Ballicre, Tindall, and Cox, price 3s., the most use¬
ful book for your purpose : it about covers the ground you mention.
A more extended work, invaluable for reference, is Muter’s ‘ Short
Manual of Analytical Chemistry,’ published by the same firm,
price 6s. 6dL [Reply to H. P. M. — 77/6.]
OBITUARY.
Williams. — On January 16, Josiah Thomas Williams, Chemist
and Druggist, of Coleford (Clos. ). Aged 72.
Riley.— On January 18, John Peet Riley, Chemist and Druggist,
of Hetton (Yorks). Aged 58.
Mather. — On January 19, William Mather, Chemist and Druggist,
of South Hylton (Durham). Aged 81.
Crarer.— On January 20, at Park Place, Coupar Angus, Mrs.
Crarer, widow of John Crarer, Pharmaceutical Chemist, Blair¬
gowrie. Aged 65 years.
George. — On January 21, William Arthur George, Chemist and
Druggist, of Pentre (Pontypridd). Aged 30.
NEWSPAPERS sent to the Editor should have the paragraphs
marked to which it is desired to call attention. Copies have
been received during the week of the following Sheffield Inde¬
pendent, Henley and South Oxfordshire Standard, Echo, Standard,
Liverpool Daily Post, Scotsman, Northern Whig.
COMMUNICATIONS, LETTERS, etc., have been received from
Messrs. Anderson, Austen, Bailes, Blythe, Brayshay, Brown, Bustard, Clague,
Cocks, Cracknell, Cross, Dyer, Dyson, Ferrall, Glyn- Jones, Groves, Harris,
Harrison, Heaver, Hick, Hill, Hogg, Hoit, Ince, James, Kelly, Kemp, Lucas,
Martindale, Matthews, Miller, Nall, Netting, Oliver, Park, Powell, Reynolds,
Roberts, Scupham, Squire, Stewart, Strachan, Wallace.
PHARMACEUTICAL JOURNAL.
101
/W f#
6,| V
' \
-J—
^-5 FEE
RCIAL CIVET.
LDHAM BRAITHWAITE.
ingredient in perfumery ; its consumption
s considerable and apparently on the increase ;
the production, however, is necessarily limited, and in consequence
the price has materially advanced in the last few years. Under
these circumstances it is not surprising that suspicion has been ex¬
cited as to the purity of much of the civet met with in commerce, the
more so since it is a product which lends itself readily to sophistica¬
tion. Having recently had occasion to examine some samples of com¬
mercial civet, I found that few data of any value for determining the
relative purity of this substance have been recorded. I therefore
applied to Mr. Bartlett, the Superintendent of the Zoological
Society’s Gardens, for an authentic sample. He has kindly fur¬
nished me with a small quantity of the secretion obtained from the
civet cats under his charge. From this I have been able to obtain
data which have been of service in the comparative examination
of commercial specimens, and which appear to be of sufficient
interest to put on record.
The civet obtained from the gardens was a chocolate -brown
stiff mass resembling date pulp in consistence. The odour was
distinctive, powerful, and not unpleasant. The reaction was faintly
acid. Examined with a lens it was seen to contain much sawdust
derived from the animals’ cage and numerous hairs. It lost 6*45 per
cent, on drying, and gave 4 ’9 per cent, of ash, but these figures are
not of any value for comparison, on account of the presence of the saw¬
dust. Upon spreading a weighed portion on an Adam’s paper and ex¬
tracting it with light petroleum ether in a Soxhlet apparatus, it was
found that the exhausted residue consisted almost entirely of sawdust
and hairs, and was practically odourless, showing that the pure
secretion is almost wholly soluble in petroleum ether. The ex¬
tracted portion deprived of the solvent and cautiously dried
amounted to 39 '9 per cent. This extracted portion consisted of a
soft brown fatty matter, a little firmer than butter, and possess¬
ing the powerful but fragrant odour of original sample, and may
be considered pure “civet.”
The total acid number of this fatty substance was next deter¬
mined in the usual manner by saponifying with alcoholic potash
and found to be 140. The odour of the soap formed in this process
was peculiar, being distinctly alliaceous, pointing to the probable
presence of a sulphur compound. On liberating the fatty acids a
marked odour of valerianic and butyric acids and other volatile
fatty acids was noted, and suggested that probably the determina¬
tion of the saturating power of these bodies might furnish a useful
figure. The whole was therefore made distinctly alkaline, and the
alcohol cautiously and entirely removed. The acids were then
liberated with a slight excess of dilute sulphuric acid, the volatile
fatty acids distilled as in Reichert’s method, and the distillate
titrated with decinormal soda solution. The volatile fatty acid
number for 1000 parts of “ civet ” was found to be 32 3.
Having obtained these data, three samples of commercial civet
were examined in a similar manner and afforded figures that are of
considerable interest. All differed from the authentic sample in
odour, having much more the smell of rancid butter and less of the
agreeable musky odour.
It will be noticed that all the commercial samples give a
markedly lower figure for volatile acids than the authentic speci¬
men, while the total acid number varies, both ways being too low in
A and too high in B and C. In all instances these figures indicate
the presence of foreign fatty matter. Sample A is noteworthy for
the large amount lost on drying : the figures here indicate the
undoubted presence of added water.
Vol. LVIII. (Fourth Series, Vol. IV.). No. 1389.
Loss at 100°
Ash .
Petrol. Ether Ext.
Total Acid, No. of Pet
rol. Ether Ext. .
Volatile Acid, No. Pet
Ether Ext .
Nature of Residue in
Petrol. Ether
to{
Sugar in Residue Insol.
in Petro. Ether .
Sample from
Zoological
Commercial
Commercial
Commercial
(Freed from
Sample A.
Sample B.
Sample C.
Sawdust).
+
30-1
12-5
23-4
+
2 1
4-4
3-9
Almost wholly
soluble.
62 -9
70-07
50-
140
108
166
175
32-3
11
11-5
9
Moist,
Hairs, etc. ;
Dry, slight
Dry, slight
sticky,
almost
odour, ster-
odour, ster-
strong ster-
odourless.
coraceous.
coraceous.
coraceous
odour.
None.
None.
None.
Present in
quantity.
The characters of the residues differed considerably. In the
case of the sample from the Zoological Gardens there was
practically nothing but hair, except the sawdust already men¬
tioned, and this residue was almost odourless. Sample A and B
gave dry residues with more or less fsecal odour, while C was
particularly unpleasant in this respect, and its viscid nature
suggested the presence of saccharine matter. An aqueous
solution of this after inversion with hydrochloric acid gave a
copious reduction with Fehling’s solution, a reaction which was
not obtained in any other instance. It is therefore adulterated
with saccharine matter as well as with other substances.
That the adulteration of civet is old established is shown by the
very interesting paper by Boutran Charland in the Journ. de
Pliarm., 1824 (the only published note upon the subject with
which I am acquainted), in which the author, after enumerating
the various adulterants used, states that the natives, in order to
obtain a greater product from their animals, introduce fatty matter
into the pouches, 'which they remove when it has become impreg¬
nated with the odour of the civet. From the fact, however, that
his sample was alkaline, evolving fumes of ammonia sufficient in
quantity to alter the colour of moistened red litmus paper when
exposed with a portion of the sample under a glass, its genuineness
is doubtful.
I am endeavouring to obtain a sufficient quantity of pure civet
to further determine the nature and composition of the volatile
bodies to which the odorous properties are evidently due.
My thanks are due to Messrs. Wright, Layman, and Umney, in
whose laboratory these experiments have been conducted.
NOTE ON GUAIACUM RESIN.
BY F. L. SMITH, WOLVERHAMPTON.
For sometime past I have observed that commercial guaiacum resin
when made into tincture leaves a considerable amount of residue.
As the British Pharmacopoeia is silent upon this point I deter¬
mined to make a quantitative experiment ; 220 grains were placed
in a bottle, together with 2 '5 fluid ounces of rectified spirit, and
after the whole of the resin had dissolved, the tincture was filtered,
and the residue was collected upon a filter paper. This residue was
washed with more spirit until 2-5 fluid ounces had been collected.
The filter paper and its contents were then transferred to a
Soxhlet’s apparatus and exhausted of any resin they might retain
by means of rectified spirit ; the filter paper and its contents were
then removed and dried at the temperature of the laboratory.
The dry residue was carefully removed from the paper, and when
weighed was found to be 34-5 grains, thus corresponding to 15 ’7
per cent, of the guaiacum acted upon. The residue was then in¬
cinerated, and an ash weighing 7 '40 grains or 3'36 per cent, re¬
mained, thus showing that the residue was mainly organic matter,
for, indeed, it appeared to be chiefly wood and bark. Now it seems
102
P EAR MACE UTICA L JOURNAL.
[Feb. G, 1897.
to me that official cognisance should be taken of this experiment,
and a note be made in the forthcoming Pharmacopoeia of the limit
of insoluble debris allowable in guaiacum resin, as is the case with
asafcetida, benzoin, and other official drugs of like nature.
The Radiator.
THE PHYSICAL PROPERTIES OF ELECTRIC WAVES.*
BY PROFESSOR J. C. BOSE.
The work of Hertz and of Fitzgerald in the investigation of the
phenomenon of ethereal vibration has invested the subject with
great interest, especially with regard to periodic electrical vibrations.
Periodic vibration may be set upby various means. If a pendulum be set
swinging or a string stretched and relaxed, the air surrounding would
be struck periodically and thrown into motion in a series of waves.
Under certain conditions such vibrations would produce the phe¬
nomenon of sound, and, under other conditions, other phenomena
would result according to the length of the wave and the fre¬
quency of oscillation. (Wave motion was shown by an arrange¬
ment of balls strung vertically on a steel support which was
rapidly rotated by an electric motor. ) It will be observed that
the periodic disturbance is trans¬
mitted along the whole body, and
if a suitable receiver is provided
in the path of the distui'bance it
responds. If the frequency of
the vibrations is increased the
wraves become shorter. The wave
movement in this case is lateral,
but an illustration of a vertical oscillation is given by the device
now shown . This consists of an elastic spring suspended by one
end, and having attached at its lower extremity a piece of string.
If the string is pulled downwards the spring is stretched, and when
the string is released the elasticity of the spring will cause it
to fly back towards its original position, the resulting alternate com¬
pression and relaxation causing the body to oscillate up and down.
The same principles are involved in electric vibrations.
If two metallic plates be charged electrically and brought
into apposition, the air between them is affected, and a
condition of tension is induced. When the plates are dis¬
charged suddenly by sparking, this tension is removed, and a wave
impulse is thus given to the medium. Suppose two metallic balls
be taken and placed side by side, one charged with positive and the
■other with negative electricity ; if now, by means of a make and
breakapparatus, these balls can be rapidly discharged and re-charged,
the interveningmedium, being alternately
rendered tense and relieved from tension,
will be made to vibrate. The mainten¬
ance of such oscillations, however, was
found to be a difficulty, for after a time
the surface of the two balls become
roughened, owing to electric action, and
leakage ensued, with a complete cessa¬
tion of oscillatory discharge. Professor
Lodge, by employing two side balls and
an interposed sphere, thought to get
over that difficulty, and it was found
that the presence of the third sphere did
improve the constancy of the vibration,
and that roughening of the sparking
balls did not so much affect the oscillations. Still, even with this
arrangement the electric oscillations after a time cease. Platinum
is found to resist the disintegrating
action of the current, and moreover,
it is not at all necessary to have a
series of sparks to produce the waves,
one break being quite enough to pro¬
duce a flash of radiation sufficient for a
single experiment. Hence in the radiator
before us the sparking balls and the
interposed sphere are of platinum, and
a single-break key is employed instead
of the usual interrupter. To describe
the apparatus a little in detail, a
modified RulimkorfFs coil (worked by a
small storage cell) charges two plati¬
num balls carried on jointed elec¬
* Notea of a lecture on the polarisation of the electric ray, delivered at the
Royal Institution. The illustrations are reproduced from the Philosophical Maga¬
zine, in which the apparatus devised by Professor Bose is described at full length.
Fig. 2. — The Radiating Box.
H>
Fie.
3. — The Spiral Spring
Receiver.
trodes, and ha v ing a larger sphere of platinum between them (Fig. 1 ).
The sparking balls are made very small to get rid of the secondary
disturbances produced by the coil itself. A very great convenience
results, too, in having short wave lengths such as these small
radiating balls give, for if we have large waves there will be a
larger degree of divergence, and it would be impossible to get
sure results for experiment. This radiator gives a wave length
of half an inch, and is very successful, the oscillations correspond¬
ing to it being computed at 50,000 millions per second. The
modified coil and the actuating cell are enclosed in a box of tinned
iron, and this again is placed in another box of stout copper to
prevent any disturbance from electric leaking or stray radiations.
(Fig. 2). In front of the box is a tube called the radiator tube,
to which may be fitted various supplementary apparatus required
in demonstrating the properties of the electric ray. The radiation
flash is produced by means of the button at the back of the box
which operates the break-key.
For the detection of these waves a modification of Professor
Lodge’s “coherer” is used. The first receiver was composed of
■ Fig. 4. — Arrangement of the Apparatus. R, Radiator ; T, Tapping Key ;
8, Spectrometer-Circle ; M, Plane Mirror ; C, Cylindrical Mirror ;
p, Totally Reflecting Prism ; P, Semi-Cylinders ; K, Crystal-
Holder ; F, Collecting Funnel attached to Spiral Spring Receiver ;
t, Tangent Screw by which Receiver is rotated ; V, Voltaic Cell ;
r, Circular Rheostat ; G, Galvanometer.
layers of metallic filings upon which the radiation effected a certain
action, possibly in the nature of re-arrangement of the particles or
a molecular change. This change can be detected by electrical
means, for the conductivity of the layers is altered by the radia¬
tion, and may be readily noted by the galvanometer. There is,
however, no dependence to be placed on this form of receiver ; it
does not respond to different vibrations. The conditions of a good
receiver are (a) it should be fairly sensitive ; (b) its sensibility-
should be uniform. Now the loss of sensibility in the coherer
seemed to be the result of short circuiting between the inner and
outer layer of filings, and this difficulty is overcome in the modified
form before you. It consists of a single layer of spiral springs of
coiled steel wire laid side by side, thus securing something like 1000
points of contact, and maintaining, by the elasticity of the metal,
a uniform pressure throughout. Even now the receiver shows
signs of insensibility at times because the sensibility depends
upon the pressure to which the spirals are* subjected and to the
E.M.F. in the circuit. But
by means of a screw (shown
Fig. 3) the pressure may be
adjusted, and the E.M.F.
may be controlled by means
of a circular rheostat. In
Fig. 5. Arrangement of Semi-Cylinders. order to prevent lateral rays
from interfering with the action of the receiver, an ebonite funnel
furnished with two hinged flaps is provided, and it is thus possible
to vary the amount of radiation collected. The receiver is in
circuit with a Daniell cell and a galvanometer, the latter of which
carries a mirror reflecting a beam of light on the screen. By
manipulating the button of the radiator box the flash of radiation
is produced sufficient to set up the necessary oscillations ; the
motion is transmitted to the receiver, the resistance in the
receiving circuit is diminished, and the resulting deflection of the
galvanometer is made manifest by the movement of the spot of
light on the screen. The general arrangement of the apparatus
for experiments is shown in Fig. 4.
Substances opaque to ordinary light permit the passage of the
electric ray, and it is seen that the galvanometer is violently
Feb. 6, 1897.]
PHARMACEUTICAL JOURNAL.
103
deflected when a solid substance, such as ebonite, is interposed
between the radiator and receiver. Water, which is transparent to
ordinary light, is opaque to the electric radiation — -water being a
conductor, and the “colour” of the invisible ray being different
from that of ordinary light. Each substance has a selective power
of absorption, i.e., allows certain kinds of light only to pass
through and absorbs the rest. A brick absorbs ordinary light,
but offers no obstacle to radiation. Water being opaque, it might
be supposed other liquids were. Professor Dewar’s investigations
gave physicists a rather rude shock by showing that at low
temperatures there is no such thing as resistance, and
one became curious to see how liquid air would behave
in relation to the electric ray. It is satisfactory to find that air
even when liquefied is transparent to the ray. (This was shown,
with acknowledgments to Professor Dewar for the loan of the
liquid air. ) The electric ray may be reflected. To show this ex¬
perimentally, a circular plate is mounted in front of the radiator-
tube, provided with a ro¬
tatory platform on which may
be placed the different articles
to be tested. The receiver
is placed on a radial arm (in¬
dexed) and always points to
the centre of the circle ; it
Fig. 6. — Showing increase of Incident Angle may, however, be rotated
on Plane Surface separating Semi-Cy- to any angle. If now a
linders, on rotating Platform. plane mirror be placed in
the centre of the circular platform and the platform be rotated
so that the mirror is at right angles to the electric beam, and
to the receiver, the beam will, if it follow the ordinary laws of
reflection, deflect the galvanometer spot. You see it does ; showing
that the electric ray is capable of being reflected just as ordinary
light is reflected. A curved mirror focusses the ray, and produces
a much stronger deflection when the receiver is placed at the point
where the reflected image is formed.
It is also possible to refract the ray. Until now it has been
impossible to determine the refractive indices of solid or opaque
substances, but the radiation waves enable us to do this.
Hertz tried to find the indices by using isosceles prisms, but the
amount of deviation rendered it impossible to get any degree of
accuracy. The method giving the best results is that depending
on the determination of the critical angle. Two semi-cylinders of
ebonite are placed on the platform, their plane surfaces facing
each other, and being separated by a slight space (Fig. 7). The beam
passing through the cylinders is focussed on the receiver, which
will always respond while the angle of incidence remains less
Fig. 7.— Electric Refractometer ; R, Radiator ; C, Receiver ; P Q, Semi-
Cylinders on Rotating Platform, with Metallic Plate interposed to
serve as a Diaphragm and cut off all but Central Rays.
than the critical angle. The platform is rotated until the plane
surfaces of the semi-cylinders are at such an angle to the beam
that refraction gives place to total reflection, and the galvano¬
meter records no action. The index is then read, and the plat¬
form rotated in the opposite direction till a similar failure of the
receiver to respond. The difference in the two readings will be
twice the critical angle, and from that the refractive index may be
readily computed.
Passing to the subject of the lecture, the polarisation of the
electric raj', the polariser consists of a grating made by cutting
parallel slots in a metallic plate, and the analyser, which is fitted
to the receiver, is a similar grating. These gratings are better than
the wire gratings of Hertz, because there is no chance of the spaces
getting out of the parallel. The polariser being placed with the
gratings vertical in front of the radiator tube, and the analyser
being similarly adjusted on the receiver, the latter responds
to the ray. If, however, the analyser be disposed so
that the gratings are exactly at right angles to those
of the polariser, the polarised ray cannot get through
to the receiver. This is due to the fact that, in the flrst instance
the radiation, vibrating vertically, was able to pass through the
vertically disposed grating of the analyser, but in the latter
instance the horizontal gratings were only open to vibrations in a
horizontal plane. If the grating on the receiver be inclined at an
angle of 45°, a portion of the ray will get through to the receiver.
Certain substances have the power of doubly-refracting light, and
of acting as depolarisers. Do they act similarly with the electric
ray? A large number of crystals do — nemalite, beryl, apatite,.
Fig. S. — Polarisation Apparatus ; K, Crystal Holder ; 8, Piece of Stratified
Rock ; C, Crystal ; J, Jute Polariser ; W, Wire-Grating Polariser ;
D, Vertical Graduated Disc by which Rotation is measured.
barytes, for instance. If crystals of these substances be interposed
between the polariser and the analyser, the ray is depolarised and
the galvanometer is deflected. It is not necessary to have large
crystals for the purpose, for the radiation waves are much longer
than light waves. The piece of apatite used just now was very
small, and could only intercept a part of the radiation, but it was
sufficient to demonstrate the depolarising effect.
Physical tension will sometimes produce polarisation. A rect¬
angular mass of paraffin wax strained by rapid cooling on two sides
only exhibits the phenomena. Pressure also is a factor. Nature
has provided a specimen of this class of substance in stratified rock,
which, it is seen, acts admirably. Tourmaline, which produces so
great an effect on ordinary light, is not of much use in the case of
the electric ray. Human hair is found to doubly refract the radia¬
tion, and common jute also ; in fact, the latter exhibits in a very
strong manner the property of absorbing vibrations parallel to its
fibres and transmitting those oscillating at right angles to that-
plane. A book, such as Bradshaw’s railway guide, will act as an
almost perfect polariser of the radiation waves.
POPULAR PHARMACY.*
BY J. C. HYSLOP.
Our lot is cast at a time in the world’s history when, more than
ever, popularity spells success. ‘ ‘ Vox populi vox Dei” itself, but
quite a modern adage, though in such an ancient dress, conveys
an idea which seems to have given the main impetus to everything
for nearly a century past, and the probable developments of which
it would stagger the mind to contemplate, for it seems to permeate
more and more widely all the undercurrents of life, social,
political, and industrial. True, the best informed minds — the
greatest benefactors to mankind — the most skilled craftsmen, join
as they ever have done in loving adoration of a “ divinity that
shapes our ends, rough hew them how we may,” yet to the best
of our finite intelligence the modus operandi of all the underlying
forces of the moral, as of the physical universe, in working out
for the greatest number the greatest good, seems more than ever
to be the result of some innate or infused life in the mass itself, of
which, if he take too small an account, your philosopher, politician,
or craftsman is altogether at sea.
I have long felt, that, as to pharmacy, never was there an avoca¬
tion which, irrespective of times or clime or local surroundings,
stood so fair for popular appreciation if only cultivated and
worked out in a legitimate manner. And in the recognition of
this fact lies, I think, the secret of the success of the founders of
the Pharmaceutical Society of Great Britain, when nearly sixty
years ago they first gave the craft “ a local habitation and a
* Report of paper read before the Chemists’ Assistants’ Association.
104
PHARMACEUTICAL JOURNAL.
[Feb. 6, 1897
name” somewhat befitting its imperial dignity and universal
importance. From the earliest times of which any record exists,
the pharmacist, long known as the “apothecary,” i. e. , “store¬
keeper,” because in primitive times a sort of druggist — a keeper of
dried or otherwise prepared medicaments to meet the urgency of
sudden sickness or accident — was the only kind of “ store¬
keeper” required. Food and clothing and other periodic neces¬
saries being provided straight from their natural fresh sources as
needed by the individual or the family itself. Hence arose the
term “apothecary,” the one who was responsible for the super¬
intendence of the “apotheca” or stoi’e, and later on “druggist,”
an artist in dried medicaments. A.S. drig = dry. This individual
was regarded always as an honoured servant of the public
welfare, at times somewhat confounded with, at others as distinct
from the actual medical practitioner, but always acting in harmony
with the physician and enjoying amongst all peoples, barbarian
and civilised alike, a reputation on a level with that of the priest¬
hood amongst the different religious persuasions of those times,
which now are seen through vistas of history as exulting in the
simple sunlight of serene divinity and now sunken down and
enslaved beneath the weight of accumulated superstitions. When
at the dawn of the Victorian era it was plainly evident that so far
as concerned our own country, this distinguished individual was in
danger of sinking to a condition lower even than that in which the
bard of Avon had depicted him some centuries before, there arose
a warm nucleus of men — the best conditioned of their craft — who,
fired with a zeal for the timely rescue of their fellows, deter¬
mined upon a scheme that should arrest the downward course of
things and lead him back to a position of honour once more, and
as if inspired with a clear forecast of what an enormous factor
public opinion was about to be in the making or marring of success
in every line of things, adopted boldly as their motto that watch¬
word of liberty and progress under which we fightto-day — “Habenda
ratio valetudinis ” — “ We must attend to the public welfare.”
One who means to go right must keep to the proper definitions
-of the words he uses. What then is pharmacy ? It is not a
science — nor a trade, nor a profession — nor yet a mixture, nor a
compound of these. As our words become better defined our
ideas are more refined, industrial activities less wasted, and
business more prosperous. Pharmacy is an art — stick to this idea,
there is more in it than appears on the surface, much more. It is
“the art of choosing, compounding, and dispensing medicines”;
cherish, I say, this definition, let no sophistry cheat you of it.
With the public there is much in a name, and it is to be regarded
as a hopeful sign that everywhere the members of the craft seem
to be awakening to the fitness of the title “pharmacist” to
designate their calling. This is a word that has come to stay, and
to flourish amongst us, an expressive one, not too long and
thoroughly comprehensive. He who practises the art of
“pharmacy” is a “pharmacist,” and his place of business is a
“ pharmacy.” This is on all fours with what has long been
recognised with respect to another artist and sister art ; there is the
art of “ surgery,” the artist in “ surgery” is a “ surgeon,” and the
place where his business is carried on is known as a “surgery.”
Surely in looking back upon the history of pharmacy in Great
Britain for the last fifty years, we cannot fairly be" dissatisfied
with the progress that has been made in the amelioration
of our lot. Few have the leisure, and, perhaps, fewer still the in¬
clination, to make the survey ; would they but do so, our advance
to-day on towards what all of us desire would be greatly
accelerated. The vulgar notion that “history repeats itself” is
no more correct than most other vulgar catchwords are, but there
is an underlying truth from which the notion has arisen and
which it serves to cover up ; the same principles of justice and
goodness are always in danger of being obstructed by the same
principles of personal greed and other impulses of evil which
change their dress, but not their nature, with circumstances, and
that conjunction of the good and the bad gives rise to similar re¬
sults at different epochs ; the same causes work the same results
by different means. From 1840 to 1852 there was an immense
amount of prejudice and heavy obstruction to be overcome before
the Legislature would sanction a Bill to give a distinguishing name
to those amongst us who were wise enough to wish for it. From
1852 to 1868 obstruction became active rather than passive, and
attempts to checkmate the cause of progress were made again and
again under various pretexts, which fortunately had to come to
grief because of their hollowness. However, a partial success
awaited these when the decisive action was fought out in the
lobbies of the House of Commons, which led to the passing of the
Pharmacy Amendment Act. The result was a compromise, or we
should have got nothing at all. The proposed Bill that would
have incorporated the whole trade into one recognised body with
one title, and retained the Minor examination as one necessary for
the assistant’s qualification only was degraded into a Poison
Bill, and made or maintained the old rift, the two classes being
still recognised as Pharmaceutical Chemist or Chemist and
Druggist, according as one chose to pass the Major or rest
content with the Minor.
What seems to-day the chief desideratum is, that recognising
these lessons from the immediate past, we should close up our
ranks, discard agitation that is started from time to time on Minor
issues, and see to spreading abroad amongst the laity a more
accurate knowledge of who and what we are, for what sort of
service it is that we are compelled by law to pass an onerous and
an expensive course of study, and a series of examinations in
various branches of knowledge before being allowed to practise as
pharmacists. Everywhere about us there are signs that the
chemist, as he is still called, is rising in popular estimation ; let
him but stand well upon his own true and proper dignity and
endeavour to dispel the ignorance that still lurks chiefly amongst
the effeminate portion of mankind — male and female alike — teach
them by precept and by practice that it is for their peculiar
convenience and welfare that he has been trained, and has
had set upon him the hall mark of authority by the
Legislature. In small matters, as well as in greater ones, let him
keep this aspect of his position before them analloyed by petty
trading matters, so as to show that he is not a universal com¬
petitor with grocers and drapers, barbers and oilshop keepers, and
all the rest of tradesmen, then the next Parliamentary move may
be expected to be a far more satisfactory one than those that have
gone before. So far as the business of a pharmacist goes, it is
entirely of a retail character. The B.P. is a compilation of data
by which we are to diagnose the genuine character of the articles
of materia medica which we are compelled to obtain through
wholesale sources, and of formula to direct us as to the compound¬
ing in small quantities of those that we are expected to prepare
for ourselves. A neglect of these considerations has often landed
men in peculiar difficulties, and tended to bring upon some of the
formulae very unjust criticism, e.g., a discussion is started in the
journals on liq. strychnin* hyd. After a lively battle pr o and con for
some weeks it suddenly leaks out that the original objector was a
wholesale manufacturer, who found that a formula given to direct
a pharmacist to make two ounces for his own dispensing counter
was not quite applicable for the preparation and storage of a hogs¬
head. We often see in print the terms “retail pharmacy,”
“ wholesale pharmacy,” “ high-class pharmacy,” and so on, which
is all rubbish. Pharmacy can be neither high nor low, it is always
more or less pure or mixed, mixed often with incompatibilities.
“Wholesale pharmacist” is a misnomer, “retail pharmacist”
pleonastic. The word “pharmacy” is not an old and ugly
one, but a real beauty, in its full health and vigour, as is the art
itself to which the word rightly applies ; we are responsible for the
maintenance of its health and loveliness ; we are the body of men
to whom the Pharmacy Acts primilarily apply, and responsible
alike for their present observance and future amendment. It
follows from what has been already said that beyond all men a phar¬
macist must be a free man, uncast in any special mould. This brings
us to the subject of education, another idea about which there exists
a sad fardel of muddleheadedness at the present day. To fit us
for the business of life we are compelled to acquire a certain large
amount of general knowledge, wrongly termed education, for
education is not the acquirement of knowledge ; and afterwards
we go in for a more accurate knowledge still of various sciences
around which the art of pharmacy revolves, or which touch its
widening circumference at various points. All this tends to educa¬
tion, but one’s education itself is the outcome of these advantages,
the resultant, so to speak, of the various forces thus gathered up
to act and react in our destined sphere to enable one to stoop with
ease and rise with dignity in the practice of a noble craft, able to
use and to enjoy life to its maximum extent because of the ability
given us in education to adapt ourselves harmoniously to all our
environment. So that bugbear of being “too highly educated,”
as it is sometimes foolishly put, melts into thin air ; there
is no such thing as being “ highly educated,” it is proficiency
or non-proficiency that is involved in the idea of education ; there
is nothing high nor low in education no more than in the art of phar¬
macy. Strict or lax — good or bad — are the only terms applicable.
( To be continued. )
Feb. 6, 1897J
PHARMACEUTICAL JOURNAL
105
PHARMACEUTICAL SOCIETY
MEETING OF THE COUNCIL.
WEDNESDAY, FEBRUARY 3, 1897.
Present :
Mr. Walter Hills, President.
Mr. John Harrison, Vice-President,
Messrs. Allen, Atkins, Bateson, Bottle, Carteighe, Corder,
Gostling, Grose, Hampson, Martindale, Newsholme, Park, Savory,
Storrar, and Young.
The minutes of the previous meeting were read and confirmed.
The Late Mr. Geo. Nind.
The President said he regretted to announce the death at an
advanced age of one of the Divisional Secretaries, Mr. Geo. Nind,
of Wandsworth. He had not the pleasure of his personal
acquaintance, but he knew him to be very loyal to the Society,
and an excellent divisional secretary. He would also remind
the Council of two interesting little presents which Mr. Nind
made to the Society in 1888. One a water-colour sketch of the
Old Clock House, West Hill, Wandsworth, the former residence
of Jacob Bell, and the other a bundle of staves from the shrubbery
of the same house, showing the interest he took in the early history
of the Society. They would all regret his loss.
Election of Students.
The following, having passed the First examination and
tendered their subscriptions for the current year, were elected
‘ ‘ Students ” of the Society : —
Ashdown, William Percy C. ; Brighton.
Avery, Edward John ; London.
Bartlet, Alexander ; Turriff.
Bennett, William Chaplin ; Bristol.
Brown, William Charles ; Birmingham.
Chapman, Frank ; Aylesbury.
Charnock, Fred ; Bury St. Edmunds.
Clegg, Harry Brook ; London.
Davis, Charles ; Biverhead.
Davison, Miller ; Durham.
Deal, William Henry ; Southampton.
Donaldson, Robert Muir ; Edinburgh.
Dowdy, Sidney Ernest ; Kennington.
Elgar, John Butler ; Fakenham.
Evans, Arthur E. ; Moretonhampstead.
Francis, James B. ; Milford Haven.
Gill, Josiah ; Melton Mowbray.
Gwilliam, John Everall ; Warminster.
Hill, Philip Robert ; Weymouth.
Howorth, Christian W. ; Plumstead.
Wilkinson, Alfred
Hunt, Frederick ; Chichester.
Illingworth, Thomas B. ; Chorley.
Jarvis, John; London.
Jeffery, George Golder ; Tring.
J enkins, Herbert ; Cricklewood.
Mogg, Ernest Hubert ; Wells, Som’t.
Morris, Evelyn Harry ; Peterborough.
Pashley, E. F. Cuthbert ; Harrogate.
Pirn, Ernest Henry ; Pontypridd.
Rapson, Florence Helena ; Bungay.
Riley, Alfred ; Bradford.
Roach, William Frederick ; Swindon.
Sharpe, Ernest T. ; Loughborough.
Shea, William A. L. ; Brighton.
Skeat, Charles ; Plymouth.
Smith, Henry Llewellyn ; Dorking.
Teale, John Oliver ; Rhyl.
Thompson, Sidney Cooke ; King’s Lynn.
Turner, Alfred William ; Lydney.
Wadsworth, George Russell ; Halifax,
■ates ; Dartmouth.
Restoration to Register.
The name of the following person, who has made the required
declaration, and paid a fine of one guinea, was restored to the
Register of Chemists and Druggists : —
The Lot for the Next Council.
The lot having been taken in the usual way to determine the
seven members of the Council who shall retire in May next, the
following names were drawn : — Messrs. Carteighe, Corder,
Gostling, Harrison, Martindale, Park, Savory.
The following, wbo remained in by lot last year, now retire by rota¬
tion : — Messrs. Allen, Atkins, Bottle, Grose, Hampson, Southall,
and Young.
The following seven remain in office another year Messrs.
Bateson, Cross, Hills, Johnston, Newsholme, Storrar, and Symes.
George Henry Nutt, Binstead, I§le of Wight.
Several persons were restored to their former status in the
Society upon payment of the current year’s subscription and a
nominal restoration fee of one shilling.
Registrar’s Report.
The Registrar’s report on the numerical strength of the Society
was laid on the table. It is printed at pp. 106,107.
The President moved that this report be entered on the minutes .
and published in the Journal.
Election of Members.
The following having passed the Major examination and tendered
their subscriptions for the current year, were elected “Members”
of the Society : —
Bowen, Edgar Cecil ; London.
Brigham, Edwin Beal ; London.
Brown, Charles ; Northallerton.
Crombie, James ; Glasgow.
Knight, William Arthur ; Leicester.
Nicholson, John Gordon ; Carnoustie.
Sargeant, Frederick P. ; Chorley.
Senter, George ; Edinburgh.
Wilson, Thomas ; Burntisland.
Election of Associates in Business.
The following, having passed the Minor examination, being in
business on their own account, and having tendered their subscrip¬
tions for the current year, were elected ‘ ‘Associates in Business ” of
the Society : — -
Atkins, William ; Newcastle-on-Tyne.
Bevan, Edward ; Swansea.
Blarney, John ; Falmouth.
Bolsover, John Thomas ; Rotherham.
Havard, Henry Lewis ; Swansea.
Neale, Charles Albert ; London.
Parry, Arthur ; Llanrwst.
Robb, James ; Leith.
Election of Associates.
The following having passed the Minor examination, and
tendered their subscriptions for the current year, were elected
“Associates ” of the Society : —
Crawhall, Thomas Currah ; Stanhope.
Ford, Jessie ; Denhead.
Golightly, Alfred Welch ; Sunderland.
Griffiths, Benjamin ; Cardiff.
Horsfield, Jessie Agnes ; Rotherham.
J ones, Sidney Clifford ; Camberwell.
Matz, Max ; Manchester.
Oliver, John ; Bilston.
Owen, Thomas P. ; Blaenau Festiniog.
Pickering, William C. ; Northampton.
Ramsaj7, William Christopher ; Dundee.
Roberts, Rees ; Blaenau Festiniog.
Simpson, Dundas ; Shotts.
Simpson, Gilbert ; Galashiels.
Thomas, Penry Sidney ; Talgarth.
Thomas, William Henry : Bristol.
Report of Finance Committee.
The report of this Committee was read by the Secretary. It was
of the usual character, and recommended various accounts for
payment.
The President (as Chairman of the Committee) moved the
adoption of the report and recommendations, which he said com
tained nothing needing special comment.
The resolution was at once agreed to.
Report of Benevolent Fund Committee.
The report of this Committee stated that only one application-
for relief was under consideration, being a case which had been
adjourned for further information, and certain letters having been
read the application was not entertained.
The Secretary reported the death, on January 13, of Elizabeth
Wilks, of Bromyard, aged 75, who was elected an annuitant in
1872.
The Vice-President, in moving the adoption of the report, said
so far as his experience of the Benevolent Fund was concerned, his
position on the present occasion was unique, there being no grant
whatever proposed by the Committee. There were only two cases
before the Committee, one of which was not considered to come
within the sphere of their operations, and in the other
case certain formal matters were not complete. He should hardly
fulfil his duty fully and completely if he stopped at this point ; but
felt that he ought to state that there were four other cases of
which notice had been given, but the formal matters in reference
to them not being completed they did not come before the
Committee. There were now already five cases to deal with next
month, and probably others would turn up, so that he hoped it
would not go forth to the country that the Benevolent Fund
Committee had nothing to do. As emphasising the great good
that the Fund did he would recall the fact that they had just
received notice of the death of an annuitant who had been on their
books for twenty-five years. It said something for the Fund that
106
PHARMACEUTICAL JOURNAL.
[Feb. 6, 1897
REGISTRAR’S REPORT.
MEMBERS, ASSOCIATES, AND STUDENTS OF THE SOCIETY FOR THE YEAR 1896.
Life Compounders.
Annual Subscribers.
Members.
Associates
Members.
Associates
Associates
in
in
not in
Students.
Pharm.
Chem. and
Business.
Pharm.
Chem. and
Business.
Business.
Chemists.
Druggists.
Chemists.
Druggists.
Number in 1895 . .
247
7
27
1357
582
1652
,, restored, 1896
7
5
11
,, elected, 1896 .
ii
1
4
53
17
127
...
...
258
8
31
1417
604
1790
Deaths, Secessions, etc. . .
8
2
...
83*
35*
139*
...
...
Total Strength of the Society ...
250
6
31
1334
569
1651
984
843
- .
1895 .
247
7
27
1357
582
1652
961
802
1896 .
250
6
31
1334
569
1651
984
846
Increase .
3
4
23
44
Decrease...
i
...
23
13
1
...
...
COMPARATIVE STATEMENT OF THE NUMERICAL STRENGTH OF THE SOCIETY
FOR 5 YEARS: 1892-96.
MEMBERS.— PHARMACEUTICAL CHEMISTS.
1892
1893
1894
1895
1896
Restored to Membership
21
12
6
10
7
Elected ,,
72
62
62
51
53
(Total additions)
93
74
68
61
60
Deaths, Secessions, etc. .
135*
89*
76*
102*
83*
Increase ...
Decrease...
42
is
8
41
23
Total Number of Annual Members ...
1421
1408
1398
1357
1334
MEMBERS.— CHEMISTS AND DRUGGISTS.
1892 1893
1894
1895
1896
Restored to Membership
4
1
6
3
5
Elected ,, .
62
37
21
15
17
(Total additions)
66
38
27
18
22
Deaths, Secessions, etc.
31*
35
30
39
35*
Increase
35
3
Decrease
...
3
21
13
Total Number of Annual Members
603
606
603
582
569
ASSOCIATES IN BUSINESS.
1892
1893
1894
1895
1896
Restored . .
36
19
11
14
11
Elected
175
182
165
159
127
(Total additions) ...
211
201
176
173
138
Deaths, Secessions, etc . .
108*
100*
126*
115
139*
Increase
103
101
50
58
Decrease ... .
...
...
...
...
i
Total Number of Annual Associates in
Business ...
1443
1544
1594
1652
1651
ASSOCIATES NOT IN BUSINESS.
1892
1893
1894
1895
1896
Increase
...
23
Decrease
Total Number of Associates
ii
24
is
19
—
not in Business
1019
995
980
961
984
STUDENTS.
Increase
Decrease
1892
1893
1894 1895
1896
140
14
8
17
44
Total Number of Students
797
8111 819
802
84i
LIFE COMPOUNDERS.
1892.
1S93.
1894.
1895.
1896.
Members Pharmaceutical Chemists ...
222
232
241
247
250
Increase .
36
10
9
6
3
Members : — Chemists and Druggists
6
6
7
7
6
Increase ...
4
1
Decrease .
• r «
...
i
Associates in Business .
14
23
25
27
31
Increase . . . .
14
9
2
2
4
* Some of these paid the life composition fee.
Feb 6, 1897.]
PHARMACEUTICAL JOURNAL.
107
ANALYSIS OF EXAMINATIONS FOR THE YEAR, 1896.
FIRST EXAMINATION.
Number of Candidates
during the Year.
Number of successful
Candidates during
the Year.
Number of Rejections
during the Year.
Number of
Examinations during
the Year.
Average number
of Candidates at each
Examination.
Average number
of Rejections at each
Examination.
Percentage of
Rejections.
1533
704
829
4
383 25
207-25
54-07
Number of Certificates received in lieu of the First Examination ... . ... 125
MAJOR, MINOR, AND MODIFIED EXAMINATIONS.
ENGLAND AND WALES.
Examinations.
Number of
Candidates during
the Year.
Number of Success¬
ful Candidates
during the Year.
Number of
Rejections during
the Year.
Number of
Examinations
during the Year.
Average Number
of Candidates
at each Meeting.
Average Number
of rejections
at each Meeting.
Percentage of
Rejections.
Major .
Minor .
Modified .
Ill
793
One Candidate p
55
260
resented himself a
56
533
nd passed.
4
4
27-75
198-25
14-00
133-25
50-45
67-21
SCOTLAND.
Examinations.
Number of
Candidates during
Number of success¬
ful Candidates
Number of
Rejections during
Number of
Examinations
Average Number
of Candidates
Average Number
of rejections
Percentage of
Rejections.
the Year.
during the Year.
the Year.
during the Y ear.
at each Meeting.
at each Meeting.
Major .
19
6
13
4
4-75
3-25
6S-42.
Minor .
656
243
413
4
164-00
103-25
62-95
THE REGISTERS OF PHARMACEUTICAL CHEMISTS AND CHEMISTS AND DRUGGISTS, 1896.
Additions during the year : —
Number of persons who have passed the —
Minor „ .
Major „ . . . 61*
Modified „ .
Number of persons restored to the Register on payment |
of a fine . )
Number of persons registered on payment of the>
registration fee, having been in business before 1
August 1, 1868 . J
503
1
17
o
523
Erasures during the year : —
Deaths . 245
Erased at the request of registered persons themselves . . 4
Erased by the Registrar in pursuance of the provision set ^
forth in Section 10 of the Pharmacy Act, 1868, after I
sending two registered letters, to which no answer has f
been received . )
Increase of numbers on the Register . 88
523
* These having already been included in the number who passed
the Minor, do not increase the numbers on the Register.
Number of Pharmaceutical Chemists on the Register, December 31st, 1896 » M • 2,253
Chemists and Druggists ... .- . . 12,913
- 15.166
108
PHARMACEUTICAL JOURNAL.
[Feb 6, 1897
they kept aged persons in comfortable circumstances for twenty-
five years, and was a strong reason why it should receive support.
The President, in putting the resolution, said he should like to
call attention to a donation of four guineas towards the Benevolent
Fund, which was collected at a smoking concert held at The Chemists’
Club a few days ago. The money was sent to the Secretary bj
Mr. H. H. Robins. They were glad to receive the money and also
glad to know that interest was taken in the Fund in every direction.
The Report was adopted.
Library, Museum, School, and House Committee.
Library.
The report of the Librarian had been received, including the
following particulars
Attendance
Total.
Highest.
Lowest.
Average.
December . . . . _ _ -
[Day .
[ Evening .
.. 359
.. 6S
28
12
4
0
14
4
Tear 1896 .
1 Day .
1 Evening .
.4307
.1312
31
20
0
0
15
6
Circulation of Books. Total.
Town.
Country.
Carriage paid.
December . .
. 221
Ill
110
£1
8s. 2 Id.
Year 1896 .
. 2071
1096
975
£12 18s,. Ojd.
Donations to the Library had been announced (Pharm. Joum.,
January 23, p. 74), and the Committee had directed that the
usual letters of thanks be sent to the respective donors.
Museum.
The Curator’s report had been received, and included the fol¬
lowing particulars : —
Attendance.
Total.
Highest.
Lowest.
Average.
December .
/Day .
• ' \ Evening .
. . 459
,. 45
41
10
3
1
14
2
Year 1896...
j Day .
.4915
42
4
18
t Evening ....
.. 409
22
0
15
Several donations had been received {Pharm. Joum., January 23,
p. 74), and the Committee directed that the usual letters of thanks
be sent to the respective donors. The Curator laid upon the table
a copy of the ‘ Report of Proceedings, with the papers read at the
•Glasgow meeting of the Museums Association in 1896.’
The Curator had reported the receipt of a letter from Mr.
Rutherford Hill, announcing that the Royal College of Physicians,
Edinburgh, had finally ratified the transference of their Materia
Medica Museum to the Pharmaceutical Society of Great Britain,
and that the Scoresby-Jackson Materia Medica collection had
been purchased for £45, in accordance with the arrangement made
by Mr. Ewing on behalf of the Society.
The President, in moving the adoption of the report and re¬
commendation, said the work of the Committee had been of the
general routine character, and the only thing of which he need
refer was the particulars relating to the valuable addition to the
Materia Medica Museum in Edinburgh. The £45 mentioned had
been, to a very great extent, provided by voluntary contributions
from their friends in the north, so that the Society would only
pay a small portion of it. The collection was very valuable and
unique. *
The resolution was unanimously adopted.
Report of “First” Examination.
January, 1897.
The following report on the examination was presented : —
Candidates.
_ _ 'v - - - -
/ V.
Examined. Passed. Failed,
324 165 159
Fifteen certificates by approved examining bodies were
received in lieu of the Society’s “First” examination.
Mr. Storrar asked leave to say a word of, personal explanation
in connection with the examinations. At the meeting of the Council
in December, when the President moved a vote of thanks to the Ex¬
aminers he took the opportunity of saying a word or two with
regard to Professor Geddes, and in the Society’s Journal he was
reported to have said that the Board in Edinburgh had worked
more harmoniously than it had ever done before. Some of the
examiners in the north took exception, he thought quite rightly,
to that, and felt considerably hurt and annoyed. He certainly
did not intend to make any such remark, and did not think he did.
He did not blame the reporters, because he no doubt spoke indis¬
tinctly, and possibly the English as spoken in Fife was not so
easily understood by them as that spoken in Bloomsbury Square.
He would simply say that he had no intention whatever
of insinuating that there was any disagreement, either now or at
any other time in the Board of Examiners in the north.
What he wanted to say was this, that the successful working
of the change made in the composition of the Examining
Board depended a good deal on the tact and courtesy of the
incoming teacher examiners, and he certainly thought they were
much indebted to Professor Geddes and Dr. Gibson for making that
change a success. They worked most amicably together with their
own examiners, and he was sure the whole Board not only worked
well together now, but always had done so.
Benevolent Fund Dinner.
The President said he might inform those members of the
Council who were not on the Benevolent Fund Committee that the
Dinner Committee had met and made certain arrangements in
connection with the forthcoming decennial Benevolent Fund Dinner.
It had been resolved that the Dinner should be held on Tuesday,
the 18th of May, at 7 o’clock, at the Victoria Hall, Hotel Cecil,
that the price for tickets should be one guinea, and that
as on former occasions the expenses, other than those covered by
the money received for the tickets, should be borne by the Fund.
They would also be glad to hear that it had been arranged
to have the services of the Mei'ster Glee Singers to render sweet
melody on that occasion, which might help to open their hearts.
He was sure the Council would be anxious to have a successful
Dinner. They would have a large company, and he trusted that
the festival would result in a large addition to the Benevolent
Fund. The decennial Dinner this year happened to come on the
Diamond Jubilee of the Queen’s reign, and no doubt during the
coming spring and summer a large number of their country friends
would be visiting London and taking part in some of the festivities
that would be going on. He hoped they would see more of their
country friends, and that if they were coming to London to take
part in what was going on in connection with the Queen’s Jubilee
that they would so arrange that the time of their visit should
include May 18.
General Purposes Committee.
The Council, as usual, went into committee to consider the
report of this Committee, which dealt with legal matters only.
On resuming, the report and recommendations were adopted, and
special resolutions were passed authorising the Registrar to take
proceedings against certain persons named therein.
FIRST EXAMINATION RESULTS.
A meeting of the Board of Examiners for England and Wales
was held on Tuesday, February 2.
Certificates by approved examining bodies were received from
the undermentioned in lieu of the Society’s examination : —
Allen, Archibald C. ; Lichfield.
Banks, Sydney Joseph ; St. Neots.
Clarke, John ; Rotherham.
Gent, Francis R. ; Middlesborough.
Harris, Frank Vincent ; Paignton.
Moore, Francis Howard ; Blackpool.
Oakley, Sydney E. ; London.
Williams, George
Pellow, Howard J ames ; Exeter.
Perkins, Geo. Mitchelson ; Evesham.
Porteous, James P. ; Grange-over-Sands.
Reader, Henry George ; Reigate.
Russell, George H. ; Burton-on-Trent.
Tilley, Ernest Alfred ; Reading.
Wilkie, John M. ; Montrose.
Wynne ; Dolgelly.
The report of the College of Preceptors on the examination, held
on January 12, was received.
324 candidates had presented themselves for examination, of
whom 159 failed.
The following 165 passed, and the Registrar was authorised to
place their names upon the Register of Apprentices or Students
Andrews, Bertram, L. M. ; Royston.
Ashkanazy, Albert W. ; Dartford.
Avery, Charles W. ; Hemel Hempstead.
Balfour, Andrew Common ; Jedburgh.
Barrass, Matthew H. ; Shotley Bridge.
Barron, William John ; Turriff.
Bazley, Bertie William ; Gloucester.
Birkett, Thomas Gilbert ; Ulverston.
Bishop, William Booth ; Turriff.
Blanchflower, Arthur F. ; Gt. Yarmouth.
Bowen, John Arthur ; Llandyssul.
Brown, W. A. P. ; Bishop Au ckland.
Bullock, 'lhomas London ; Liverpool.
Burr, Harold ; Tottenham.
Burton, Harry Osborne ; Liverpool.
Butler, Wm. Morgan ; Tenby.
Caison, James Howatson ; Ayr.
Cook, James; Dumfries.
Cooper, George Paterson ; Leith.
Craig, Edwin Forbes ; Aberdeen.
Cressey, David Edward ; Billingliay.
Culbert, William Spencer ; Glasgow.
Gumming, James ; Kirkcaldy.
Curtis, Herbert N. Robt. ; Brighton.
Feb. 6, 1897J
PHARMACEUTICAL JOURNAL.
109
Dales, Joseph Wardle ; Louth.
Davies, Ralph Cecil ; Milford Haven.
Denton, Norwood ; Pontefract.
Dodd, David ; Manchester.
Douglas, Mary Anne T. ; Edinburgh.
Dow, James ; Huntly.
Dow, John Roy ; Rothes.
Dunbar, James ; Dufftown.
Earlam, Ernest ; Frodsham.
Eaton, Harry Oswald ; Leeds.
Edwards, Robert John ; Wrexham.
Elvery, Herbert Fred. ; Southampton.
Ferguson, Alexander Sim ; Dollar.
Ferrier, James ; Laurencekirk.
Fieldgate, Fredk. Ward ; Colchester.
Fouracre, Robert ; London.
Fox, Ernest Nicholl ; Liverpool.
Freke, Alice ; London.
Geake, Henry, jun. ; Dundee.
Glasscock, John Laybank ; Norwich.
Godson, George Frederick ; Lincoln, i
Gowans, Duncan Stewart ; Hawick.
Grant, Peter James ; Gran town.
Green, Harold Walter ; Birmingham.
Gregory, Joseph Day kin ; Mansfield.
Hadley, John Arnold ; Birmingham.
Haines, James Hunt ; Birmingham.
Hardy, Digby Wrangham ; Malton.
Harker, George C. ; Richmond, Yorks.
Hartley, William James ; Blackpool.
Hay, James Alfred ; Bebside.
Hazelby, Thomas Weaver ; Swaythling.
Henry, Alexr. McLaren ; Wishaw.
Heslop, C. W. B. ; Newcastle-on-Tyne.
Hicks, Joseph ; Edinburgh.
Hirst, Harold C. ; High Ackworth.
Hirst, Joseph Luther ; Slaithwaite.
Hodges, Francis Sully ; Bristol.
Howse, Leonard Augustus ; Croydon.
Huntbach, Herbert ; Preston.
Hunter, Harry ; Sheffield.
Husbands, Frederick ; Stapleford.
Hutcheon, James ; Turriff.
Hymans, Herbert ; London.
Jobling, Edward ; Sunderland.
Jones, Daniel Thomas ; Swinton.
Jones, Edgar Alfred ; Ripley.
Jukes, Bernard C. ; Wellingborough.
Kendrew, William Holme ; Southport.
Kennedy, Herbert William ; Aberdeen.
Kenington, Robert Barker ; Grantham.
Kermode, JohnW. ; Castletown, I.M.
Lewis, William M. ; Pembroke Dock.
Leyshon, Thomas St. Leger ; Spalding.
Lindsay, John ; Montrose.
Low, John Hill ; Fraserburgh.
Lowis, John William ; Bedale.
Luke, Cecil B. ; Stonehouse, Devon.
McCabe, Aubrey Joseph ; Sunderland.
McCaig, Robert ; Dumfries.
McCartney, Walter ; Darwen.
MeConnachie, John ; Keith.
McGregor, James ; Cullen.
McIntosh, Finlay ; Pitlochry.
March, Fredk. William ; Thrapston.
Massey, Joseph ; Manchester.
Matthew, Arthur ; Rochdale.
Melbourn, Newell Evens ; London.
Metcalfe, William Edward ; Keighley.
Miller, Donald George ; London.
Young, David Ait
Mills, Edward ; Denbigh.
Murray, John Macfarlane ; Edinburgh.
Newboult, Robert ; Bradford.
Nicholson, William ; Glasgow.
Nicoll, Thomas ; Edinburgh,
Paterson,' William John ; Elgin.
Pattullo, James Watson ; Edinburgh.
Pearce, Andrew Hingstone ; Horwich.
Peberdy, Tom Cooke ; Leicester.
Pirie, Robert Corsane ; Arbroath.
Pitchford, Amy C. W. ; London.
Pritchard, Walter ; Carnarvon.
Rae, John ; Templand.
Ramsay, Robert Sparks ; Dundee.
Rees, David Andrew ; London.
Reid, Clifton Harold ; Desford.
Reynolds, Frank ; Droitwich.
Rice, Thomas James ; Birmingham.
Robertson, Alexander ; Partick.
Robertson, William John; Betchworth.
Selby, William Tordiff ; Edinburgh.
Sharp, Murray ; Dunfermline.
Shaw, Duncan William ; Edinburgh.
Shaw, Samuel ; Whaley Bridge.
Shearer, John Alexander ; Fraserburgh.
Shepherd, Harry ; Newcastle-on-Tyne.
Shiels, Henry B. ; Ayr.
Sim, William ; Strichen.
Simpson, Francis Ernest ; Bloxham.
Sizer, Charles Henry ; Hull.
Slaney, Charles Newnham ; Deal.
Smart, Agnes ; Edinburgh.
Smith, Harry ; Stokesley.
Smith, James Sidney ; Truro.
Smith, Mark Elkington ; Louth.
Smith, Sydney ; West Bridgford.
Southern, Lewis ; Nottingham.
Stewardson, A. ; Newcastle-on-Tyne.
Strang, Duncan ; Callander.
Temperton, Harry ; Long Sutton.
Thomas, Wilfred John Ladd ; Begelly.
Thomson, Charles Samson ; Ayr.
Thomson, Thomas ; Selkirk.
Thwaits, George Rose ; Edinburgh.
Tinker, George ; Holmfirth.
Townley, Tiburtus ; Tarporley.
Trattles, William Ernest ; Whitby.
Turner, David ; Auchtermuchty.
Verrall, Ada ; Swanboro’.
Walmsley, William Ewart ; Halifax.
Walters, Gwilym Jenkin ; Treherbert.
Warren, Pierce Harold ; Derby.
Watkins, Ernest Arthur E. ; Bwlch.
Watson, David ; Arbroath.
Watt, William Hamilton ; Glasgow.
Webster, Digby ; Chester.
West, David ; Fraserburgh.
Whitehead, John William ; Burnley.
Wiley, Harold ; West Hartlepool.
Williams, Harold John ; Glasgow.
Williams, Josiah Thos. D. ; Bradford.
Willson, Harry Briggs ; Peterborough.
Wilson, George ; Newcastle-upon-Tyne.
Wilson, William S. ; Stratford-on-Avon.
Wood, Harry Mayall ; Hanley.
Wood, William ; Uttoxeter.
Woodhead, Stanley ; Newcastle, Staffs.
Woolley, George C. ; Burton-on-Trent.
Wormald, John E. ; Luddenden Foot.
Yates, Francis Harold ; Blackpool,
en ; Dunfermline.
The questions set at this examination were published in the
Pharmaceutical Journal for January 16, p. 49.
The following is a list of the centres at which the examination
was held, showing the number of candidates at each centre, and
the result: —
Candidates. Candidates.
Examined, j
Passed.
Failed.
Examined.
Passed
Failed.
Aberdeen .
22
15
7
2
5
Birmingham .
15
11
4
15
8
7
Brighton .
4
2
2
Lincoln . - . . . .
6
5
1
Bristol . . .
3
i
2
23
9
14
Cambridge . . . ..
1
i
0
26
12
14
Canterbury . .
I
i
0
Manchester .
24
12
12
Cardiff! . .
3
i
2
Newcastle-on-Tyne ....
13
8
5
Carlisle . . .
12
3
9
•2
1
1
Carmarthen . . . . .
9
6
3
Norwich . . . .
5
2
3
Carnarvon . .
2
1
1
17
8
9
Cheltenham . . „ _ .
2
1
1
4
1
3
Darlington . .
7
5
2
Penzance . .
i
1
0
Dundee .
10
6
4
Peterborough _ _ _
7
4
3
Edinburgh .
37
21
10
Plymouth . . .
5
1
4
Exeter .
1
0
1
Sheffield .
5
2
3
Glasgow . .
18
8
10
i
0
1
Hull” .
3
1
2
3
2
1
Inverness .
5
2
3
York ...1 .
3
1
2
PARLIAMENTARY NOTES AND NEWS-
The Companies Bill has re-entered the parliamentary arena,
having been read a first time in the House of Lords on the 1st
instant. There is no reason to suppose that it will not progress
strictly in accordance with the precedent set last Session ; for
there are many difficulties to face, and reference to a Select Com¬
mittee appears to be a reasonable way of getting those difficulties
dealt with. The purification of commercial methods is no light
undertaking, but if the Government has any real desire to grapple
with the unhealthy conditions created by the Companies Acts, the
task is a long way from the impossible. But it is just possible
that the Bill introduced last Monday by Earl Dudley on behalf
of the Board of Trade, is only one of those “dummy” items
which go to make up a sessional programme, and merely represents
the redemption of a pledge given in the Queen’s Speech. The
second reading of the Bill has not yet been fixed, and meanwhile,
one is rather anxious to see history repeat itself by the agency of
Lord Herschel, who, it will be remembered, last Session gave
notice of his intention to move for the insertion of a clause pro¬
tecting personal professional titles.
Mr. Mundella has given notice that he intends to ask the
President of the Board of Trade when it is proposed to introduce
the Bill of last year which rendered the use of metric weights and
measures permissible in this country. One would imagine that so
mild a Bill as that referred to would not arouse any serious oppo¬
sition, but the sturdy patriotism of the member for King’s Lynn,
which conceives the greatness of the empire to be inseparably
associated with the English quart, will certainly make itself heard,
and there are higher authorities than Mr. Bowles who are prepared
to oppose the introduction of the metric system on weightier
grounds.
Early Closing ought to succeed this Session if the number and
activity of the members in the House who follow the cult were any
criterion of success. There is, however, so much lack of unanimity
among them as to methods that it is doubtful if any practical
result can ensue. At the present moment there are three sects of
early closers in the House, and three Bills. First, there is "Sir
John Lubbock’s Shops (Early Closing) Bill, the provisions of which
are pretty well known to chemists by this time. It is down for
second reading on February 10, and has been honoured by three
“blocking” notices. Then there is the Shops Bill evolved by
Mr. Burns, Sir Charles Dilke, and Mr. Davitt, which regulates
the closing hour for every day in the week, and seeks to
remedy certain sins of omission in the Factory Acts. This
Bill is also awaiting the second stage, and, like its rival,
labours under the disadvantage of three “ blocks.” Mr. Duncome
is the high priest of the third party, and has charge of a Bill to
provide one half -holiday a week for all shop assistants. This
measure is at present unopposed, and thus stands in a rather more
favourable position than its fellows. Its second reading was tabled
for the 3rd instant, but it was not reached. With this division of
forces, the interests of shop assistants are not likely to advance
very rapidly.
110
PHARMACEUTICAL JOURNAL.
[Feb 6 1897.
THE STUDENTS’ PAGE.
THE FLOWERS OF FEBRUARY.
"" Many of the plants enumerated for January may still be
looked for in February. In the following list the names
italicised are those of plants used in medicine. It includes
plants that have been seen in flower during February during
mild winters, but many of them, if the present inclement weather
continues, may not be found in flower until March, or in the
north even later. Wild Flowers : Ranunculus ficaria, Helleborus
fceiidus, Viola hirta, Potentilla fragrariastrum, Beilis perennis,
Tussilago farfara, Primula vulgaris, Lamium purpureum, Nepeta
glechoma, Yinca minor, Daphne laureola, Mercurialis perennis,
Corylus avellana, Ulmus campestris, Narcissus pseudo-narcissus,
•Garden Flowers : Eranthis hyemalis, Helleborus purpurascens,
Anemone hepatica and A. angulosa, Arabis alpina, Saxifraga crassi-
folia, S. sancta and S. burseriana, Pyrus japonica ; Cornus mascula,
Pulmonaria officinalis, Rosmarinus officinalis, Vinca major, Erica
carnea, Forsythia suspensa, Mandragora vernalis, Galanthus nivalis,
Narcissus obvallaris, Hyacinthus azureus. Forced and Greenhouse
Flowers : Bielytra spectabilis, Pelargonium sp. , Barosma crenulata,
Cineraria sp., Azalea sp., Nicotiana tabacum, Capsicum sp., Solanum
jasminoides, Primula sinensis, etc., Cyclamen sp., Plumbago rosea.
Euphorbia splendens and E. jacquinkeflora, Dendrobium nobile,
Gonvallaria majalis, Hyacinthus sp., Tulipa sp., Aloe plicatilis,
A. arborescens, A. succotrina, Eucharis amazonica, Narcissus sp.
Lamium album. — This plant may generally be found in flower
early in the year on sheltered hedgebanks. It affords an excellent
illustration of the characters of the Labiate, and its flowers are
large enough to examine easily. The stem is square, the leaves
are alternately opposite (decussate), and cordate-ovate, with a
crenate-serrate margin. The flowers are arranged in axillary cymes
(vertieillasters). The corolla is gamopetalous (he. , the petals united),
irregular, ringent (wide open), the stamens four, two longer than the
other two, didynamous, the calyx campanulate, and containing four
pyrenes (one seeded half -carpels), surrounding the base of the style,
which readily falls off. In other words, the ovary is divided into four
segments, each containing one seed. The inflorescence is somewhat
puzzling, since it is irregularly developed. It is composed of two or more
sessile groups of three flowers (cymes ), in each of which the central one
opens first and the two lateral buds subsequently. Owing to the
crowded growth, however, the inner lateral flower-bud is often not
developed, and thus the inflorescence seems to consist of flowers
irregularly arranged. The stem is quadrangular, and owes its
firmness to a formation of thickened cells (collenchyma) in the
angles (see Green’s * Botany,’ p. 309, fig. 675), which may be easily
seen under the microscope, if a thin transverse slice is taken off
with a razor.* The method in which this flower is fertilised by
insects is explained fully in Lubbock’s ‘British Wild Flowers in
Relation to Insects,’ p. 143-146. The character of the ovary
should be especially noted, since this distinguishes the Labiate
from the Scrophulariaceae, which have also irregular flowers with
didynamous stamens.
NOTES ON THE B.P.
Blither. — Compare the action of sulphuric acid on excess of
alcohol (as in making ether) with the action of alcohol on excess of
sulphuric acid. In both cases ethyl hydrogen sulphate is first
formed : —
C2H60H + H2S04 = C2H5HS04 + H20.
Whfen excess of alcohol is present, this reacts with the ethyl
hydrogen sulphate to form ether and sulphuric acid : —
C2HBHS04 + C2HB0H = (C2H5)20 + H2S04.
This regeneration of sulphuric acid explains why a limited quan¬
tity of acid is capable of converting such a large quantity of
alcohol into ether. The action, however, becomes gradually slower,
and eventually stops, owing to the accumulation of water, produced
as shown in the first equation. A secondary reaction also takes
place between the alcohol and sulphuric acid, the mixture blacken¬
ing owing to the oxidation of alcohol, while the sulphuric is
reduced to sulphurous acid. Some of this latter acid distils over
with the ether and is neutralised and removed as calcium sulphite
by agitation with the slaked lime. On the other hand, when
* The hairs on the stem are three-celled, and may be compared with those of
Gapsella bursa-pastoris, which has one-celled hairs with a glandular base, and
stellate hairs on the same leaf.
excess of sulphuric acid is present, the ethyl hydrogen sulphate is
decomposed at the higher temperature to which the mixture is
heated, ethylene and sulphuric acid being formed : —
C2H5HS04 = C2H4 + H2S04.
The commercial methylated ether, prepared from methylated
spirit, contains some methyl oxide, derived in an analogous manner
from the methyl alcohol contained in the wood naphtha used in
methylation. Methyl oxide is a gas at ordinary temperature, hence
methylated ether begins to boil at a lower temperature than pure
ether (ethyl oxide).
Note that although ether is a very light fluid its vapour is very
much heavier than air. The molecular weight of ether (he., the
relative weight of its molecules in the state of gas compared to
molecules of the standard (hydrogen as 2) is 74 [(C2H5)20 = 74]. By
Avogadro’s hypothesis equal volumes of gases at the same tem¬
perature and pressure contain the same number of molecules.
Now the molecule of ether (m. wt. 74) is 37 times heavier than the
hydrogen molecule (m. wt. 2), and the vapour density of
ether is 37. Air is 14-44 times heavier than hydrogen (determined
directly by weighing known volumes of the two gases). Ether
vapour will therefore be rather more than 2 4 times
heavier than air.
Alcohol Amylicum. — Normal amyl alcohol,
CH3 - CH2 - CH2 - CH2 - CH2( OH),
is contained in small quantities in fusel oil. Two of its possible
seven isomers, namely, iso-butyl carbinol,
gg>CH-CH2-CH2(OH),
C H
and active amyl alcohol, Aj£5jj>CH — CH2(OH), are, however, the
chief constituents. Note that these are both primary alcohols, i.e.,
contain the CH2OH group. The term ‘ ‘ active” applied to the latter
alcohol refers to its power of rotating a ray of polarised light, this
action being due to the asymmetric carbon atom (marked with an
asterisk in the formula). This is called “ asymmetric ” because it
is combined with four different groups or elements — in this case, C2H5,
CH;j, H, and CH2OH (carbinol). Small quantities of propyl and
butyl alcohols and other substances are also present. The student
is recommended to read a good account of alcohol and fermenta¬
tion, such as that in Roscoe and Schorlemmer’s ‘ Organic
Chemistry. ’
Alumen. — Solution of potassium hydrate precipitates aluminium
hydrate, the precipitate re-dissolving in excess to form potassium
aluminate. Compare this with the behaviour of chromium and
ferric salts towards KOH : ferric hydrate is insoluble in excess of
KOH ; chromium hydrate dissolves in the cold to form a potas¬
sium compound similar to the one formed by aluminium hydrate,
but the chromium hydrate is re-precipitated on boiling the solution.
Alumen Exsiccatum. — If alum be overheated in drying, some
oxysulphate is produced, and the dried product does not dissolve
completely in water.
Ammonium Bromidum. — Production of a yellow colour (free
bromine) on moistening with dilute sulphuric acid indicates
presence of ammonium bromate. A similar reaction will be more
fully dealt with under potassium iodide.
Ammonii Garbonas. — Carbamic acid, whose ammonium salt forms
one of the constituents of the official Ammonii Carbonas, is a very in¬
teresting body on account of its relations to carbonic acid and urea.
Carbonic acid CO<jQ forms two amides CO<^qj|- and CO<j^-g2
by replacement of one or both its hydroxyl groups with the amide
group, NH2. The first is carbamic acid, its acid properties being
dependent upon the presence of the (OH) group (hydroxyl) associ¬
ated with the (CO) group (carboxyl). If the hydrogen be replaced
by NH4, we therefore get ammonium carbamate, CONH2'ONH4.
The second amide, carbamide, is the well-known body urea.
Ammonii Nitras. — When heated it is resolved into nitrous oxide
and water NH4N03 = N20 + 2HaO. Nitrous oxide for inhalation as
an anaesthetic must be carefully freed from nitric oxide, a little
of which is formed when ammonium nitrate is heated. This is
done by passing the gas through solution of ferrous sulphate which
retains the nitric oxide, forming the black compound, which is
met with in the ordinary test for nitrates with FeS04and H2S04.
Feb. 6, 1897]
PHARMACEUTICAL JOURNAL.
Ill
Pharmaceutical Journal.
LONDON: SATURDAY, FEBRUARY 6, 1897.
THE COUNCIL MEETING.
A T the opening of the meeting the President announced
the death of Mr. George Nind, who was for many years a
stauticli supporter of the Pharmaceutical Society, and latterly
■occupied the position of Divisional Secretary for the Parlia¬
mentary Division of Wandsworth (see Obituary, p. 120).
Upon taking the lot to ascertain which seven members of
Council would retire from office, the result showed that the
members to remain upon the Council are Messrs. Bateson,
Cross, Hills, Johnston, Newsholme, Storrar, and Symes.
The additions to the Society comprised 9 Members, 24
Associates, and 41 Students.
The Registrar’s report of the number of Members, Asso¬
ciates, and Students connected with the Society, the results
•of the examinations in 1896, and upon the Registers of Phar¬
maceutical Chemists and Chemists and Druggists was pre¬
sented, but did not lead to any comment.
The report of the Finance Committee was also adopted
without any further reference to it than the President’s
•remark that it contained nothing unusual.
The report of the Benevolent Fund Committee was of an
exceptional character, inasmuch as it did not recommend
any grants, the only application made since the last meet¬
ing of Council not having been entertained, and the
only incident in connection with the Fund was the death
of Elizabeth Wilks at the age of 75. In speaking of the
unique character of this month’s report the Vice-President
remarked that it must not be regarded as a precedent for
the future, since there are several applications to be
considered so soon as the formalities in connection with
them have been completed. He also referred to the fact
■of the annuitant lately deceased having been in receipt
of an income from the Benevolent Fund for the last
twenty-five years, as a proof of the good service that
could be rendered in keeping aged and necessitous persons in
comfortable circumstances. No stronger reason for giving
general support to the Benevolent Fund could well be found.
The President endorsed that view of the matter and ex¬
pressed his gratification at being able to call attention to an
instance of interest in the Benevolent Fund, from the receipt
of a donation of four guineas, forwarded by Mr. Robins,
the money having been collected ou the occasion of a smoking
concert recently held at the Chemists’ Club.
In the report of the Library, etc., Committee, the chief
circumstances mentioned were the final ratification of the
transfer of the Materia Mediea Museum of the Royal College
of Physicians, Edinburgh, to the Pharmaceutical Society,
and the purchase of the Scoresby- Jackson collection of
Materia Mediea. A very valuable addition has thus been made
to the Museum of the Pharmaceutical Society in Edinburgh,
the cost of which has been, to a great extent, met by volun¬
tary contributions from Scottish members.
After the report of the results of examinations had been
read, Mr. Storrar mentioned that the report of his remarks
in regard to Professor Geddes at the December meeting of
Council did not convey the intention he had in speaking
on that occasion, and some members of the Examining
Board had, as he thought justly, felt hurt by it. He wished
to explain that he did not intend to insinuate that there
had ever been any disagreement in the Board of Examiners ;
but merely to say that the successful working of the change
made in the composition of the Examining Board depended
a good deal on the tact and courtesy of the ihcoming outside
examiners, and to express obligation to Professor Geddes
and Dr. Gibson on that ground.
The report of the General Purposes Committee on legal
matters was considered, as usual, privately, and the Council
afterwards adopted its recommendations, besides authorising
the Registrar to take proceedings in various cases which had
been reported.
Before the conclusion of the general business the
President informed the members of Council that the
Committee appointed to make arrangements for the forth¬
coming decennial Benevolent; Fund Dinner had decided that the
Dinner should take place on Tuesday, May 18 next, at 7 p.m.
in the Victoria Hall of the Hotel Cecil. He also intimated
that the services of the Meister Glee Singers had been secured
for that occasion, an attraction which might help to open the
hearts of the company, and he trusted that country friends
coming to London to take part in the festivities with which
the Queen’s sixty years’ reign will be celebrated will so
arrange their visit as to include May 18, and that they would
also be present at the Benevolent Fund Dinner.
PHOTOGRAPHY IN COLOURS.
The production of coloured photographs by the direct
action of light is an ever-promised but, up to the present,
not realised development of the pictorial art. The latest
approach to this result has been obtained by M. Villedieu
Chassagne, of Paris, who has developed a process origin¬
ally suggested by Dr. Adrian Dansao. An ordinary
negative is taken and immersed in a special solution before
developing and fixing in the usual manner. The finished
negative and prints from it do not differ in appearance from
other negatives or prints, but on treatment of the prints
with blue, green, and red solutions respectively, they
take up the appropriate colours in the appropriate parts,
the three colours blending to give all varieties of hue.
Specimens so prepared are on view at the rooms of
the Society of Arts, and amongst others before whom the
whole process has been demonstrated, at King’s College, are
Sir Henry Trueman Wood, Professor Thomson, Mr.
Herbert Jackson, Captain Abney, and other prominent
scientists and photographers.
Amongst the negatives treated at the demonstrations
were some taken by those gentlemen, and a print from
one showed with perfect distinctness the colours of a bunch
of flowers Sir Henry had bought at Covent Garden on his
way to the College. The composition of the four solutions
is as yet a secret, but there is little doubt that the one first
used acts as a mordant and in some way alters the nature of
the film, so that it becomes capable of exercising a selective
action, as it were, upon the colours employed. The coloured
solutions appear to contain aniline dyes, and they are probably
of varying degrees of acidity or alkalinity. Tne prints, after
treatment with the mordant and washing, are immersed first
in the blue, then in the green, and finally in the red solu¬
tion, the reactions that occur resulting in the production of
the different intermediate tints. The finished prints are
wonderful productions, and the new process indicates a marked
advance in the colouring of photograph®, though the colora¬
tion is not produced by the direct action of light.
112
PHARMACEUTICAL journal.
[Feb. 6, 1897
ANNOTATIONS.
The Association Generate Pharmaceutigue de Belgique is
a national organisation, membership of which is open to every
Belgian pharmacist who is willing to pay a subscription of two
francs. It was formed between thirty and forty years ago for the
purpose of uniting the pharmacists of the country in the attempt
to secure better laws for pharmacy. But during the past year the
Association has been re-organised with a view to developing the
scientific side of the profession. The President is Professor Ranwez
and the Secretary is M. Duyk, both of whom have had the advantage
of a special scientific training. Professor Ranwez occupies the chair
of Pharmacy in the University of Louvain and is an enthusiastic
worker. M. Duyk practises as a pharmacist in Brussels.
The Eighth International Pharmaceutical Congress, to be
held at Brussels this year, during August, is being promoted by
the Association Generale de Belgique, and at that Congress it is
proposed to bring forward for discussion matters of direct
pharmaceutical interest, rather than technical chemical subjects
as at the Congress in 1885. The Congress has the support of the
Belgian Government and professors of the different Belgian
universities, and it is hoped to secure a representative gathering
of pharmacists for the occasion. As stated last week, readers de¬
siring further information should apply to M. Duyk, 102,
Chaussee de Wavre, Brussels, who will also be glad to hear from
the secretaries of all British pharmaceutical associations which may
be interested in the approaching Congress. We shall publish a
list of the questions to be discussed in next week’s J ournal.
Dr. R. Robert, who has for ten years occupied the position of
Professor of Pharmacology at the University of Dorpat, has re¬
signed his chair in order to accept an appointment that has been
offered to him of director of a sanitary establishment in Germany.
His departure from Dorpat has given rise to expressions of con¬
siderable regret in the local newspapers, not only on account of
the successful influence he exercised as a teacher, but equally so
because of the social popularity he had gained.
Death of Dr. Hans Hermann Julius Hager. — The German
papers record the death of this notability of the pharmaceutical
world at the advanced age of 89. In early life, after leaving
school, he was four years as pupil in an “ apotheke” in Salzwedel,
and even during that period commenced the literary work by
which he afterwards became famous. In recognition of the merit
of his various publications he was excused his assistant examina¬
tion. On passing his qualifying examination he took a business at
Fraustadt, which he carried on with the assistance of a pupil for
seventeen years. He then removed to Berlin and devoted himself
entirely to scientific and literary pursuits in connection with phar¬
macy. The number of works he produced was very considerable,
and several of them were translated into various languages. His
services to the art were recognised not only in Germany, but in
other countries, and at the time of his death he was an honorary
member of thirteen pharmaceutical societies.
The Death of Sir Spencer Wells in his seventy-ninth year
is reported from Cap d’ Antibes. The eminent surgeon entered
on his medical career through the gateway of apprenticeship, at
Barnsley, Yorkshire, and after spending twelve months with a
parish doctor at Leeds and subsequently working in the Anato¬
mical School at Dublin, he went to St. Thomas’s Hospital, London.
Becoming a member of the Royal College of Surgeons in 1841 he
next entered the Navy as assistant-surgeon, and gained experience
during the Crimean war. Ultimately he settled in practice in
London, gradually acquired a reputation as a specialist in the
diseases of women, and proved the practicability of ovariotomy.
He was created a baronet in 1884 for his distinguished services to
the medical profession and to humanity, and during the same year
became President of the Council of the Royal College of Surgeons.
The Swansea Chemist’s Bankruptcy, referred to briefly, last
week, is the subject of a letter received from Mr. John Davies,
chemist and druggist, of that town, in which he says the “former
proprietor ” of the business, mentioned but not named in the note,
was his brother, who is now dead. Further, he declares that all the
statements made by the bankrupt and accepted by the Registrar as
correct, were totally incorrect and misleading. We have great
pleasure in publishing this disclaimer, and much regret that
anything published in the Journal should appear, even
inadvertently, to reflect upon the conduct of a deceased
chemist, who is described as having been an honour¬
able and straightforward man, but the whole of the
statements in our note were made public by the bankrupt at his
public examination, reports of which appeared in the local news¬
papers and, lacking information to the contrary, there was no
reason for assuming those reports to be incorrect. It may be
worth while observing in regard to matters of interest to chemists
and druggists reported in local newspapers, that we have no
means of testing the accuracy of these reports, and it would be
well in the case of any inaccuracy appearing in the published
reports for the individualsjchieflv interested, or the local secre¬
taries for the respective districts, to communicate the true state
of affairs to the editorial department of the Journal at once,
and thus prevent further publication of the errors.
Saffron from Eastern Countries will be regarded with dis¬
favour if a report appearing in the Daily Neivs should be confirmed.
According to the Vienna correspondent of that paper, the Sanitary
Council of Constantinople has resolved, on account of the plague, to
prohibit pilgrimage from India and Persia to Kherbela, a favourite
place of burial with the Shiites and other Indian sects. It is said
to be the custom for the bodies of wealthy Shiites to be laid aside
until a caravan leaves for Kherbela, and, the report proceeds, “ the
dead are sown up in carpets with large quantities of saffron to
preserve them. At Kherbela the bodies are buried, and carpets-
and saffron are sold to European dealers.” Saffron may not beany
the worse for this treatment, but most people would prefer it in
its virgin freshness.
The Anatomy of Ipecacuanha has been studied by Dr. Albert
Schneider, who publishes the result of a comparison made by him¬
self of the histological features of Rio and Carthagena roots
(Journal of Pharmacology, iv., 1). These results lead him to the
conclusion that it is possible, not only to distinguish powders
prepared from the two varieties of ipecacuanha, but also to detect
the presence of a comparatively small percentage of Carthagena
powder when present as an adulterant of Rio powder. It is said
to be necessary to make at least ten examinations before
formulating a conclusion as to whether or not the adultera¬
tion exists, but it appears extremely doubtful whether even
then anyone would be safe in deciding the matter on such evidence
as Dr. Schneider considers sufficient. Thus, he states that “the
presence of single discoid starch-grains having a diameter of from
17y to 23jU indicates the presence of the Carthagena powder,” and
this statement is printed in italics to render it more emphatic.
But the starch-grains of Carthagena ipecacuanha can hardly be
Feb. 6, 1897]
PHARMACEUTICAL JOURNAL.
113
termed discoid, nor do they show such markings as appear in the
illustration given by the author. The correct shape of the grains,
which are in reality somewhat angular, was portrayed by Greenish
two years ago (Ph. J., liv., 690), and the same work showed that
they attain a size of 17m to 22m, the size being greatly dependent
upon the age of the root. Dr. Schneider’s conclusions appear,
therefore, to be based on insufficient grounds. It is somewhat re¬
markable, too, that he does not refer to the work of either Ranwez
or Greenish.
The Proposed Attfield Testimonial was referred to in the
Journal for November 14 last. We have now received a circular
from Mr. John Moss, in which it is suggested that an illu¬
minated album containing an alphabetical list of the names of
as many as possible of his past students and admirers of his work
should be presented to Dr. Attfield, and stating that Professor
Herkomer, R.A., has volunteered to do a plate of Dr. Attfield
by his new method, so that the Committee will be enabled to
present a signed proof engraving on India paper to everyone who
subscribes ten shillings to the testimonial fund. The Chairman of
the Committee is Mr. Charles Umney, and the Secretary Mr. J ohn
Moss, who will be glad to receive signatures of those who have
benefited by the teaching or writings of Dr. Attfield, either ac¬
companied by subscriptions to the fund or not, at 39, Tressillian
Road, St. John’s, London, S.E.
A Record in Quinine has been established by the latest drop in
the price of that article, sulphate warranted to answer the British
Pharmacopoeia tests having been offered in one hundred-ounce tins
at eightpence per ounce for the foreign, or three-halfpence more for
Howards’. Foreign makers reduced their price to the extent
of twopence per ounce, but Howards and Son one penny per ounce
only. We are informed by Messrs. Wright, Layman and Umney
that the sudden reduction was due to the action of some manufac¬
turers in Paris and Milan, who are not within the Convention, and
that within a few hours of the drop being announced prices again
advanced, though considerable sales at the reduced rates had mean¬
while been effected.
Higher Research in Chemistry in its relation to manufactures
is to be further encouraged by the foundation of one or more
Fellowships, tenable at the City and Guilds of London Institute.
The Leathersellers Company is providing the necessary funds, a
grant of £150 a year being offered for the purpose. The amount
of the grant attached to each Fellowship will be determined by
the Executive Committee of the Institute, regard being had as far
as practicable to the nature of the research, the time required
to complete it, and the merits of the candidate, subject
in all things to the approval of the Company. The Fellow¬
ships are confined to natural-born British subjects, who have com¬
pleted a full three years’ course of instruction in the Chemical De¬
partment of the Central Technical College, or who are otherwise
duly qualified in the methods of chemical research in its relation
to manufactures. They will be tenable for part of a year or a
whole year, and may be renewed for a second or third year, all
researches by Fellows being carried out at the Central Technical
College. Applications for Fellowships must be addressed to the
Honorary Secretary of the Institute, Gresham College, E.C.
Diet and Medicine in China serve a writer in the Cornhitt
Magazine as a topic. He remarks that the commonly received
opinion that the Chinese as a nation habitually feed on rats and
mice is quite erroneous, though in the city of Canton “spatchcock ”
rats — that is, rats split open and dried — are commonly sold in the
streets for edible purposes. Boiled rat is supposed to be good for
rheumatism and chills, and also to make the hair grow more
rapidly. The flesh of camels, donkeys, and goats is regularly
eaten, without much regard being had to the manner in which the
animals meet their death ; birds’ nests of gelatinous nature and
sea slugs are invariably present at first-class Chinese feasts, and
human milk is hawked about for sale in Amoy, old men
being the purchasers. Turtles’ sinews are considered good
for pains in the joints, and in Nanking there is a local custom of
chewing horses’ sinews. The skin and bones of deceased elephants
are kept for the Emperor’s consumption when unwell, and His
Majesty’s father is said to have been cured of some malady by
means of donkey’s skin, whilst ground rhinoceros horn is con¬
sidered to be of great therapeutic virtue. Sharks’ fins are nearly
always given with a big dinner, and castor oil is said to be some¬
times used in cookery. Wild Manchurian ginseng is described
worth its weight in gold. It is used as a food tonic, and mar¬
vellous “repairing” qualities are attributed to it.
Chinese Ideas of Chemistry, Anatomy, and Physiology were
exceedingly primitive until late years. Air was supposed to per¬
meate the body through imaginary tubes, and physicians confined
their diagnosis almost entirely to feeling the pulse, which was
supposed to show ^pventy-two separate indications. Rabies in dog
or man is now treated with a tisane, taken hot, composed of
ginseng and a variety of other herbal remedies. Cantharides is
used by some Chinese doctors for hydrophobia, but red bamboo
root, Geranium nepalense, and ginseng are prescribed in preference.
Cholera is also treated with a special mixture of herbs taken
along with rice spirit, Aconitum variegatum being administered
when the hands and feet show great coldness, and Carica papaya
if they are shrivelled. Water is swallowed through a stale tobacco
pipe to counteract the effects of cobra bite, shed snake-skins are
used for eye medicines, and wasp stings are cured with raw taro.
The lily bulb is used for lung diseases, petrified crabs for heart
disease, oyster-shell dust for itchy irritations, mumps, and
certain swellings allied to rickets. “ Toads’ eyebrows ” are
claimed to be effectual for provoking sneezing, and thus clearing
the head. The favourite way of committing suicide is by swallow¬
ing opium, and arsenic is chiefly used for murder.
“ The Gas Companies of the United Kingdom,” observes the
Pall Mall Gazette, are of course like Caesar’s wife, but it is sug¬
gested that it would, nevertheless, be a relief to hear some satis¬
factory explanation of certain startling figures, the accuracy of
which should be indubitable, as they come straight from the pages of
a Government publication. These figures contrast the average con¬
sumption by the householder and the street lamp of gas supplied by
gas companies with that of municipal authorities. The annual
average consumption by the private consumer of gas supplied by
companies is, it appears, as much as 49,100 cubic feet, whereas of
that supplied by local authorities it is only 28,100 cubic feet. In
other words, the average consumer who uses companies’ gas burns
nearly twice as much as the consumer who is supplied by local
authorities. Although this difference is surprisingly great, it is
thought it may be accounted for on the ground that London, which
probably has richer householders and larger shops than other parts
of the kingdom, is companies’ ground. ‘ 1 But can this also apply to-
the street lamps ? The public lamps supplied by companies burn
17,190 cubic feet of gas, whereas those burning municipal gas only
consume 14,970 cubic feet. How is this ? Will some gas com¬
pany enlighten our darkness ? ”
114
PHARMACEUTICAL JOURNAL.
[Feb 6, 1897
LITERARY NOTES.
Kelly’s London Medical Directory for 1897, the ninth
edition, contains 542 pages as against 519 in the edition for 1896,
but it is pointed out in the preface that the expansion is due, as in
the past, to the greater fulness of the entries rather than to an
increase in the number of medical men practising in London and
its suburbs. As usual, the names and addresses in the directory
are followed by statements of qualifications and particulars of con¬
tributions to medical literature. This section is very complete,
and correspondingly useful. Much information is also given
rqgpecting the General Medical Council, the various examining
bodies granting medical diplomas and degrees, the Local
Government Board, Lunacy Board, Metropolitan Asylums
Board, societies of various kinds, and many other matters
of direct interest to physicians, surgeons, and pharmacists.
Every London pharmacist at least, should find it advantageous to
possess a copy of the book, which is published at a moderate
price (6s. 6 cl.) by Messrs. Kelly and Co., Limited, 182, High
Holborn, W.C.
Lean’s ‘ Royal Navy List ’ is a bulky volume of nearly five
hundred pages, which ought to be perused with great
interest at the present time by many readers, in view
of the increased attention devoted generally to the matters
of which it treats. Amongst other matters it gives details
of the war and meritorious services of naval officers,
of which there is no other public record whatever, the dates
of all commissions from first entry to the present time and retire¬
ments, also the dates of birth of admirals, captains, and officers of
Royal Marines. In addition official details are recorded here of acts
of gallantry for which various officers have received the Victoria
Cross, Albert Medal, and medals of the following societies, viz.,
Royal Humane, Royal National Life-Boat, Shipwrecked Mariners’,
Lloyd’s, and Liverpool Shipwreck and Humane. Under the names of
the ships are placed the battles in which those ships have taken
part, the same as the battles are placed on the colours of a regi¬
ment. In the retired lists will be found a very large number of
the Civil appointments held by officers, and at the foot of each
page are the decorations and causes of special promotion, given in
full. The list is published quarterly at the price of 7 s. 6 cl. , and
each quarter it is enlarged by the addition of new matter, the
pages being open to any information of interest to officers, and
every class of officers being dealt with in the same way. There is
good ground for the claim that there is no work of the same kind
published of so exhaustive a character for any other profession, for
the editor, Colonel Lean, appears to have done his best to turn out
a perfect ‘Navy List.’ The publishers are Messrs. Witherby and
Co., 326, High Holborn, W.C.
The Feeding of Infants is a matter of growing importance,
and Dr. Edmund Cantley’s work on ‘ The Natural and Artificial
Methods of Feeding Infants and Young Children’ (J. and A.
Churchill, London, 7 s. 6 d.), is a welcome addition to the literature
of the subject. The work is designed to give a description of the
present state of our knowledge in this direction, sufficiently
concise for the busy medical practitioner and the overworked
student, yet adequate for the purpose. Comprehensive chapters
on the physiological processes involved in lactation and on the
physiological chemistry of infantile dietetics are followed by
remarks on the management of breast feeding, the characters
and composition of human milk, and the contra-indications to
breast feeding, together with the methods of weaning. Next in
order comes the study of cow’s milk, its composition and characters',,
its supply from one cow only or otherwise, and the preparation from
cow’s milk of a fluid resembling human milk. This introduces the-
whole question of the management of artificial feeding, and after
referring to the micro-organisms in milk and methods employed1
for their destruction, the author shows what effects are produced
by heat and attenuants on the curdling of milk, a matter of extreme
importance. The remaining chapters deal with subsidiary
methods of preparing the milk of cows and other animals for the-
food of infants, proprietary foods, the diet after weaning, the-
transmission of disease by breast milk, the feeding and growth of
infants, and other matters, whilst an appendix is devoted to
the preparation of suitable foods for infants and children and
other useful information. Altogether the book is a most
excellent one and deserving of careful consideration.
“Exposures of Quackery” is the title selected by the Editor
of Health News for two small paper-covered volumes containing
reprints of articles that have appeared in the pages of that
publication. Vigorous in style, though perhaps a little free at
times in his statements of facts, the author has produced matter
which will be productive of much good if he can induce the general
public to read and digest it. It is to be feared, however, that the
habit of self-medication has gained too firm a hold on the people
of this country for any loosening of the bonds to be effected yet
awhile. But meanwhile no harm can be done by pegging away
continually. The volumes are published at Is. each by the Savoy
Press, Ltd., 115, Strand, W.C.
The Botanist’s Pocket Book, by W. R. Hayward (George Bell
and Sons, London and New York), is so well known to botanists
as the most compact and handy British flora for reference when
botanising at a distance from home, that this latest reprint of the
book needs only to be made known to the few who have not
already heard of it. Since November, 1872, when the first edition
appeared, there have been seven re-issues. Unfortunately the
work was stereotyped, and consequently subsequent additions have
had to be inserted in the appendix, and there has been no chance
for the author to bring it up to date (as regards names and
arrangement of species) with the ‘ London Catalogue ’ and Bentham
and Hooker’s ‘ Genera Plantarum.’ To those who dislike the constant
change of names the retention of the old and well-known names,
used twenty years ago, will be welcome rather than otherwise, hut it
is much to be regretted that the publishers have not permitted
the author to recast the whole work. Now that a definite
rule has been laid down and accepted by the majority of
botanists for the retention of the first name with a.
correct description published since 1753, the work
might well have been brought into accord with the rule.
This would have ensured a still larger circulation than the work
has at present, and it may be hoped that in the next issue, which
should at the present rate occur in three years’ time, the work will
be recast on a sound basis, and that the appendix of additions,
which now includes twenty-six pages, will be intercalated in the
body of the text. The additions in the present volume consist of
six new plants, one of which, Carex rhyncophysa, is by a printer’s
error spelt rhyncophasa. It may be suggested to the author that
the analysis of the genera would be more convenient to the botanist
if placed at the head of each natural order. A lapsus calami that
should also be amended occurs under My osurus minimus, “spikes
slender,” the inflorescence being a one-flowered scape.
Feb. 6, 1897]
PHARMACEUTICAL JOURNAL.
115
JflEETIflGS Op SCIENTIFIC SOCIETIES
— — — ♦ -
London Institution, Monday, January 25. — Professor C.
V. Boys, F. R.S. , whose work in the minutiae of physical pheno¬
mena is so well known, occupied a very interesting hour in re¬
vealing to a large audience the existence and behaviour of
Capillary Ripples.
It is not an easy thing to compress within the space of sixty
minutes the record of as many months of patient research, but by
a judicious suppression of scientific explanation Professor Boys
was able to give a fair idea of what to the popular mind is a quite
unsuspected — because unseen — property in liquids. After dwell¬
ing for a short time on the visible examples of wave motion,
ranging from the quarter of a mile long Atlantic “ roller ” to the
tiny wavelets in a glass or cup of water, the Professor proceeded
to show that the law as to the relation between the length of
waves and their rate of progress does not hold good for extremely
short waves. It has been found that the rate of progression of waves
is directly proportional to the square of their length, i. e. , twice
the length means four times the rate. But when one comes to
deal with wave lengths of one-tenth of an inch, observation reveals
a reversal of the law. In point of fact the slowest wave movement
seems to be attained when the wave length is about three centi¬
metres. Below that point, in the case of water, experiment shows
that the smaller the wave the greater the rate of movement. The
reason seems to be that in the large waves the principal factors are
the force of gravitation and the property of buoyancy ; the one
tending to pull down the crests, and the other to fill up the
hollows. Capillarity — or that contractile power of the surface
film of a liquid — can have very little scope in such cases. In very
small waves or ripples, however, capillarity is everything and
gravity practically inoperative.
The ripples on the surface film of a liquid move with ,such
rapidity that they are ordinarily not visible to the human eye.
They are started by the slightest movement, and dart all over the
surface. To reveal them it is necessary to have recourse to
mechanical devices. If a dish of mercury be taken (and one prefers
mercury because it reflects light from its surface better than
water) and placed upon a heavy metal disc which is suspended in
a suitable manner, accidental ripples occasioned by passing traffic
and similar causes are avoided, and one is free to make the ripples
under conditions favourable for observation. A tuning fork is now
taken, and attached to the prong is a glass style, which is
adjusted so as to just touch the surface of the mercury. The light
from an electric arc lamp is directed upon the liquid, and the
reflected rays are passed through a condenser, and so to the
screen. If now the tuning fork be gently tapped the mercurial sur¬
face will be agitated in ripples around the circular point of the
glass style. As yet, however, no movement is seen on the screen.
Why ? Because the surface is oscillating at the rate of 200 a
second— far too rapidly for human sight to detect.
But suppose a rotating disc having a series of apertures
is placed between the reflected beam and the screen in such a
manner as to intercept the light 200 times a second, then when the
movements of the wheel and the ripples coincide, the phenomenon
will be rendered visible and the ripples will be seen as though they
were motionless. (This was very beautifully demonstrated, and
the screen showed a series of concentric rings around the stimu¬
lating point. ) A lower toned fork gives a rather larger wave and
somewhat slower, and on putting two vibrating styles on the
surface of the liquid attached to forks of differing tones the
resulting ripples interfere one with another, producing radiating
bands of absolute stillness at the point of interference. Thus the
ripples behave precisely like waves of light and sound waves. The
curious thing is that though the ripples cannot be seen by unaided
sight, the interference rays are visible. Reflection may be
shown by floating in the mercury a slip of thin glass, such as
is used for covering microscopic specimens. The capillary ripples
strike against the edge of the glass and are reflected and, as
you can see, give rise to the interference bands, where . the
advancing waves meet or intercept the reflected waves. It will
be observed, too, that a “shadow” is thrown by the slip,
be., behind the obstruction there are no ripples, or at ieast only a
few faint ones, and they are caused by the vibration imparted to
the glass slip by the advancing ripples. The edges, however, do
not cast sharp shadows, and it may be distinctly seen that there
is a tendency in the waves to curl round the corner a little, exactly
in the same manner as waves of light are known to do.
The lecturer closed an all too short discourse with the exhibition
of a series of very beautiful photographic slides of the various
phases of capillary phenomena — slides which would themselves
well occupy an evening in describing.
Linnean Society of London, Thursday, January 21. —
Mr. C. B. Clarke, Vice-President, in the chair. — Messrs. Robert
Barnes and F. G. Sinclair were admitted Fellows of the Society.
Fossil Antlers.
Dr. John Lowe, F.L.S., exhibited some fossil antlers of Cervus
elaphus of unusually large size from Southern Fen, Cambridge.
The dimensions given were : — Length along outside curve,
R. 42-6 in. ; L. 41 in. Circumference above burr, R. 11 6 ; L. 11.
Greatest inside width 37 in., at top 32 6. With these were also
exhibited various fragments of implements and weapons
which had been discovered in proximity, showing that
the animal had lived contemporaneously with man. — Dr.
H. O. Forbes referred to similar antlers of great size which
had been discovered in Lancashire during the cutting of the Man¬
chester Ship Canal, and which were preserved in the Liverpool
Museum. — Mr. J. E. Darting showed drawings of large antlers
found at Bourne End in 1894 during the construction of the new
viaduct over the Thames, and at Boston, Lincolnshire, in 1895, by a
man ploughing. It was remarkable that while the antlers of Red
Deer at the present day showed a marked deterioration in size and
weight when compared with those obtained in a fossil state in
England, this was not the case with Roe Deer. He had seen no
fossil horns of the Roe which were superior in size to those of the
same species procurable at the present time in Scotland. The
reason for this had not been explained.
Peculiar Markings on Shells.
Mr. Horace Monckton, F.L.S., exhibited specimens of a common
freshwater mollusc, Limncea peregrd, collected by him at the
Howietoun Ponds, Selkirkshire, showing a variation from the
normal type in being more or less banded. The banding was in
every case confined to the last whorl of the shell, and often to the
outer portion of the whorl, although in one or two cases it was
arrested before reaching the mouth of the shell. Mr. Monckton,
after describing the position and nature of the ponds referred to,
was inclined to attribute the variation in question to the abundance
of food supplied for the Salmonidce reared there, and to
the absence of lime from the water. — Mr. B. B. Wood¬
ward, F.L.S., exhibited a similar variation in shells of
Limncea stagnalis, wherein the banding wTas longitudinal — a
peculiarity which had been recorded by Mr. T. D. Cockerell.
— Sir James Maitland, Bart., gave the results of an analysis
which had been made of the water at Howietoun and Craigend,
with a view to determine the bearing it might have on the growth
of fish and variation in the shells of the Mollusca referred to.
Eczema caused by Hyacinths.
The Secretary read a letter from Mr. J. Y. Johnson, of Fun¬
chal, Madeira, commenting upon Dr. D. Morris’s exhibition
(November 5) of raphides composed of oxalate of lime in the bulbs of
hyacinths, the handling of which had produced a form of eczema.
Mr. Johnson mentioned a parallel case in Richardia cethiopica, a
beautiful aroid known to gardeners as the Lily of the Nile. The
laundresses at Funchal had tried to utilise the starch obtainable
from the corms, but complained of the irritation in the hands pro¬
duced by it, which, on examination, was found to result
from the presence of numerous needle-shaped raphides, as in
the case of the hyacinth-bulbs referred to. Dr. G.
Elliott Smith read a paper on “ The Origin of the
Corpus callosum ; a comparative study of the Hippocampal region
of the Cerebrum of Marsupialia and certain Cheiroptera.” Tie
author entered into a detailed comparison of the portion of the
brain named in Perameles nasuta and Nyctophilus timoriensis, and
showed that the latter presents one of the lowest known terms in the
Eatherian series. The paper was criticised by Dr. St. George
Mivart, Dr. Keith, Dr. Robinson, and Prof. Howes. — On behalf
of Dr. J. Gilchrist a paper was read, “On the Minute Structure
of the Nervous System of the Mollusca.”
116
PHARMACEUTICAL JOURNAL.
'[Feb. 6, 1897
Royal Institution, Friday, January 29. — Professor J* C.
Bose, D.Sc. , Professor of Physical Science in the Presidency
College of Calcutta, delivered a lecture which, though it bore the
title of —
“The Polarisation of the Electric Ray,”
might more accurately have been described as treating of the
physical properties of electric waves (see page 102). The lecture
theatre was filled with the members of the Institution and their
friends, and among those attracted by the reputation of Professor
Bose’s special work in physics were Lord Rayleigh, Professor Syl-
vanus Thompson, and Professor Dewar. The historic lecture table
was crowded with apparatus and accessories, which aroused a very
considerable amount of curiosity and interest by reason of their
novelty — the Professor’s radiator and receiver representing the
very latest advance in the domain of electrical science.
Royal Institution, Monday, February 1. — Sir James
Crichton-Browne, M.D., F.R.S., Treasurer and Vice-President,
in the chair. — At a general monthly meeting the following were
elected members : — Mr. Alfred Louis Cohen, Mrs. Delaforce, Sir
Charles A. Elliott, K.C.S.I., LL.D., Mr. John Lawson Johnston,
Dr. A. Liebmann, Mr. T. George Longstaff, Mr. Howard Marsh,
F.R.C.S. , the Rev. E. G. C. Parr, M.A., Mr. Charles Rose, and
Mr. Edward P. Thompson. The special thanks of the members
were returned to Sir Frederick Abel, Bart., K.C.B. , for a donation
of £50, and to Mr. J. Wolfe Barry, C.B. , for a donation of £25 to
the fund for the promotion of Experimental Research at Low
Temperatures.
THE WORLD Op PHARMACY.
- ♦ - -
BUSINESS MEETINGS.
Liverpool Chemists’ Association, Thursday, January 28.
— Mr. A. C. Abraham, President, in the chair. — The annual report
was presented by the Secretary, Mr. H. O. Dutton, and the
Treasurer’s statement by Mr. John Bain, both showing a
satisfactory state of affairs as regards the work and monetary
condition of the organisation. Votes of thanks were passed to the
officers — Secretaries and Treasurer — to whose exertions in a great
measure the well-being of the Association was due. The seven
retiring members of the Council, Messrs. Bain, Buck, Cowley, Davies,
Thompson, Wardleworth, and Wokes, were re-elected, with the addi¬
tion of Mr. Prosper H. Marsden, Teacher of Pharmacy at University
College. The usual votes of thanks were accorded to the officers
relinquishing their posts on the motion of Mr. Alexander,
seconded by Mr. P. H. Marsden. A communication had been
received from the Pharmaceutical Society of Brussels, asking for
delegates from the Liverpool Chemists’ Association to be appointed
to attend a congress or pharmaceutical conference to be held in
Brussels during the coming summer. As no date was mentioned
and the particulars given were somewhat vague, it was decided to
leave the matter over until more definite information was forth¬
coming, the President remarking that if any members wished to
be accredited as delegates he should be glad to receive their names.
Inaugural Address.
Mr. A. C. Abraham, who remarked that it was nearly ten years
since he had the honour of occupying the chair before as President,
said he would endeavour to deal shortly with a few matters of
public interest such as were often brought up at the meetings in
the early days of the Association. The subjects dealt with
included the new water supply of Liverpool ; the dangers attend¬
ing the use of water gas in the city ; the advantages, from a
sanitary point of view, of the introduction of electric lighting ;
and the establishment of a complete course of pharmaceutical
education by the University College authorities. The Phar¬
maceutical Society, Mr. Abraham pointed out, has for years
been aiming at a compulsory curriculum, with the object of
raising the educational standard of the profession, but its Council
had always felt that it could not go to Parliament and ask for the
needful powers unless it could show that there were sufficient
schools in the country in the control of independent public bodies
ready to supply the necessary educational facilities for such a
curriculum. The establishment of the Liverpool University College
lectures rendered the aspirations of the Pharmaceutical Society
and those who agreed with it more easy of attainment. Neverthe¬
less, whilst he welcomed this addition to local educational
facilities, he had no desire to forget the good work which had been
done by the private school conducted in their midst, under the-
auspices, to a certain extent, of the Association.
Plymouth, Devonport, Stonehouse and District
Chemists’ Association, Wednesday, January 27. — Mr. G.
Breeze in the chair. — The Secretary (Mr. Jas. Cocks) opened
a discussion by offering a new suggestion for a scheme for aug¬
menting the funds of the
The Benevolent Fund,
in which ladies were to take a prominent part, as suggested
in the Pharmaceutical Journal of December 24. After a long-
discussion it was decided to defer the same to a subsequent
meeting ; meanwhile the local secretaries were requested to try
and redouble their energies in obtaining additional subscriptions
for the same.
New Cheap Rate for London Parcels.
This matter was brought forward by Mr. J. Harvey Bailey, and
Curtiss’ tender to the members of the Association was accepted at
2s. 6 d. per month for parcels under twelve pounds from London,
one only from the same house, but as many as the chemist likes-
from different houses daily ; above that weight, 2s. 3d. per cwt.
after deducting the twelve pounds.
Appointment of New Committees.
Mr. Maurice being indisposed, Mr. Cantle read a paper by the
former on “ C.A.M.W.A.L.” A small Committee was formed, con¬
sisting of Messrs. Maurice, Maitland, Cocks, Barge, and Park, to
consider the same. — The Secretary reported that owing to the
rapid increase of the duties of the Association, the members of the
General Committee found that they had not the necessary time to
devote to educational and trade matters. Two special Committees
were then formed : —
Trade. — Hie Chairman and Secretary (ex officio), Messrs. Bailey, Park, Roper,
Martin- Johnson, and Condy U’Ren.
Educational. — The Chairman and Secretary (ex officio), Messrs. O. A. Reade,
J. R. Johnson, J. D. Turney, R. F. Roper, and J. A. Buckley.
Mr. Park moved the following resolution : —
“ That this Association, whilst approving of the work already accomplished by
the P.A.T.A., reaffirms its confidence in its aims and objects, and hopes it -wilt
receive still greater support from the retail trade in the immediate future.”
This was seconded by Mr. Barge, and carried unanimously.
- — The President (Mr. G. Breeze) announced that he and
the Secretary (Mr. Jas. Cocks) would attend the supper of the
Exeter Chemists’ Association on the following night. It was
unanimously resolved that a fraternal message be presented to
them, with hopes that they would long be a centre of usefulness
and benefit to the trade.
Exeter Association of Chemists and Druggists, Thurs¬
day, January 28. — Mr. J. Hinton Lake, President, in the chair. —
Mr. P. F. Rowsell (the honorary secretary) stated that at the
recent annual meeting it was proposed that the Association should
elect an honorary solicitor, and the name of Mr. C. R. M. Clapp
was mentioned. It was thought very desirable, as many other
associations had their honorary solicitors, that they should have
theirs, and Mr. Clapp was considered to be a suitable gentleman
for the office. Mr. Lake and himself had waited on Mr. Clapp,
who expressed the pleasure with which he would accept the office,
provided he was appointed by the Association. Mr. Clapp, if
elected, would give them advice on any point of the Pharmacy
Act, and in the event of a case being taken up, he would naturally
be instructed. — Mr. J. Bartleet (Heavitree) said he had great-
pleasure in moving that Mr. Clapp be elected. — Mr. E. Lemmon
seconded the resolution, which was carried unanimously. — Mr.
Rowsell reported that he had received a letter from Mr. W. S..
Glyn-Jones, the Secretary of the Proprietary Articles Trade Asso¬
ciation, drawing attention to the following resolution which hia
Council had recently passed : —
“ That the Council regrets to notice the action by the Charles A. Vogeler Com¬
pany in relation to the chemists of Bradford, and recommends the various
local associations connected with the P. A. T. A. to convey to this firm their
disapproval of the action it has taken.”
Feb. 6, 1897]
PHARMACEUTICAL JOURNAI
117
Mr. Glyn-Jones had also stated in the letter that he would be glad
if the Exeter Association would take the earliest opportunity of
sending an expression of opinion to the Vogeler Company in refer¬
ence to their action. He was confident that if the various local
associations who were heartily supporting them, were to
forward resolutions condemning the action taken by this company,
that it would have a salutary effect, not only upon them, but upon
all proprietors who were apt to ignore the decided feeling which was
being shown by the trade in favour of the movement. — Mr. Rowsell
said he did not think it was necesssary for him to explain what
the action of the Vogeler Company had been; they had learnt it
from the trade journals. Suffice it to say that he thought it was
their duty to pass a resolution, such as was suggested in Mr. Glyn-
Jones’ letter. It had been passed by similar associations
throughout the country, and some of those wholesale pharmacists
who worked in a very high-handed sort of way needed to have the
matter pointed out to them, and to be told what the feeling of
chemists was on the subject. — Mr. E. Lemmon moved that the
suggested resolution be passed. This was seconded by Mr. E. F.
Stone, seconded by Mr. J. Bartleet and Mr. Vinden, and
carried unanimously. — It was decided that at the next meeting of
the Association the question of the desirability of extending the
operations of the Association, so as to include the surrounding
district, be considered.
The Annual Dinner.
The dinner of the Association immediately followed the meeting.
The President (Mr. J. Hinton Lake) occupied the chair, and was
supported by the Right Worshipful the Mayor of Exeter (Mr. R.
Pope), the Sheriff of Exeter (Mr. T. Wilson), Mr. A. W. Clayden,
M.A. (Principal of the Exeter Technical and University Extension
College), Mr. T. Linscott, J. P., Mr. George Breeze, J. P. (President
of the Plymouth, Devonport, Stonehouse and District Chemists’
Association), and many others. The toast of the evening, that of
“ The Exeter Association of Chemists and Druggists,” was
proposed by the Chairman, who said the objects of the Association
were briefly told in the three words ‘ ‘ Sociability, trade, education. ”
He then proceeded to give a historical account of the progress of
the Association, and explained at length what it had done in the
matter of providing facilities for technical education. Local chemists
were urged to impress upon their pupils the advantage of acquiring
the needful technical training for passing the Minor examination in
Exeter. — Mr. E. Lemmon and Mr. J. Bartleet acknowledged the
toast. — Mr. P. F. Rowsell next gave “The City of Exeter,”
and the Mayor, the Sheriff, and Mr. Clayden responded, the last-
mentioned explaining the local educational arrangements for phar¬
maceutical students. The toast of “The Visitors,” proposed by
Mr. D. Reid, was responded to by Mr. Geo. Breeze, J.P., who
said the Plymouth Association were desirous of expressing their
cordial feeling of friendship towards the members of the Exeter
Association. The Exeter Association had evidently entered upon
a good work, and was doing that work in an energetic manner.
They felt that these associations of chemists and druggists were
very much needed, more especially at the present time, when they
could not but feel that the trade was being terribly crippled by
various opposing forces. They felt that the need of combination
was more than ever required amongst chemists and druggists, and
they were pleased to find that chemists and druggists themselves
were beginning to realise that fact. Within the past three or four
37ears a large number of associations had been established, and he
found there were now between forty and fifty local associations of
chemists and druggists. He looked upon that as an omen of good.
Those associations must be of very great benefit ; they enabled
them to meet together, they enabled them to talk over matters
affecting the trade and act wisely and discreetly. Not only that,
they enabled them to give facilities for the education of the rising
members of their associations by forming classes and schools, and
getting specimens for them which no single individual could possibly
a ccumulate. — Mr. J. Cocks also replied. He said he should like to see
the Exeter Association extended so as to include the surrounding
towns, such as Tiverton and Crediton. The Plymouth Association
was particularly anxious to extend also, that they might join
hands with Penzance and Exeter. — Songs and recitations were given
during the evening by Messrs. Wynne Tighe, H. W. Gadd, J. W.
Lake, A. Guest, Jackson, Donald Wilson, and H. J. Stanbury.
Mr. Guest presided at the piano, and the gathering separated
with the singing of “Auld Lang Syne” and “God Save the
Queem”
Chemists’ Assistants’ Association, Thursday, January 28.
— Mr. Charles Morley, President, in the chair. — The attendance
at this meeting was very meagre, owing probably to the fact that
the Chemists’ Club “smoker” was being held at the same time..
After the preliminary business had been dispatched, Mr. J. C.
Hyslop read an interesting and instructive paper on —
Popular Pharmacy.
At the conclusion of the paper the President, in the course of his
remarks, said there was one thing about Mr. Hyslop’s paper which
they were bound to notice, and that was the love he bears for the
calling he follows, the calling of pharmacy.— Mr. W. Moore, A.I.C.,
wished to know how the public may be taught the meaning of tho
word “ pharmacist,” as he believed many people hardly know who
or what that individual is. — Mr. S. Summer, while of opinion that
the title “pharmacy” is a good one, did not agree with Mr. Hyslop
as to its popularity. He thought “ drug store ” more popular at the
present time. He quite approved the remarks in the paper on ‘ 1 neat¬
ness.” — Mr. George Roe thinks the pharmacist is a most useful indi¬
vidual, who, however, does not always realise the responsibility of the
position he occupies. The good opinion of the “ ordinary man ”
he believes is increasing in favour of the chemist’s shop, and a
well-known physician had stated that he did not know of any
position to which there is so much responsibility attached as to a
dispenser of medicines. — Mr. Hyslop, after replying to the
remarks made, said that magistrates were now beginning to
recognise the importance of the chemist or “pharmacist,”
inasmuch as they had recently decided that an article sold by a
chemist is a drug, while the same article sold by a grocer is not.
— Mr. A. R. Melhuish moved and Mr. C. E. Robinson seconded
a vote of thanks to Mr. Hyslop, which was carried by accla¬
mation.
Brighton Junior Association of Pharmacy, Wednesday,
January 27.— Mr. W. H. Andrews read a paper on Sponge,
in which he dealt very fully with the natural and commercial his¬
tory of this very interesting commodity, remarking that although
it was an article of everyday use with almost everybody, very few
really knew what it was. — Mr. Howes next read a paper on the
new illuminant, Acetylene, and also gave a practical illustration
of the preparation of that gas from calcium carbide and water,
the light obtained being used to project numerous lantern slides
upon a screen.
Edinburgh Chemists’ Assistants’ and Apprentices’
Association. — Friday, January 29, Mr. James McBain, Presi¬
dent, in the chair. — Mr. John R. Thompson read the following
paper on the —
Determination of Mercury in Ammonio-Mercuric Chloride.
Some time ago my attention was called to the fact that com¬
mercial ammonio-mercuric chloride of mercury varies in composi¬
tion. An examination of five samples from different sources gave
the following results.
Percentage of Hg
determined as Hg2Cl2-
A = . 7153
B = . - . 71-56
C = . 73-05
D = . . 75-01
E = . . . . 76-80
In course of the analysis I discovered that the method of deter¬
mining the mercury as metal was open to error, even when much
care was exercised in the details of the process. There was loss
in drying the metallic mercury, and at this stage the loss of even
a small quantity works out to a large error in the percentage.
Determination as sulphide, though less defective, also failed to give
concordant results, although free sulphur was thoroughly removed
by washing with carbon bisulphide. I next tried the method of
determining the same samples by reduction to subchloride,
Hg2Cl2, and weighing. For this purpose I employed a solution of
potassium hypophosphite acidified with hydrochloric acid, instead
of the phosphorous acid which is generally used. By this means
reduction is ensured, as the phosphorous acid is newly liberated.
The details of the process are as follow : — A weighed quantity of
Ammonio-mercuric chloride is dissolved in hydrochloric acid in a
precipitating beaker. To this the acidified solution of potass um
hypophosphite is added, when a precipitate of Hg2Cl2 is
almost immediately thrown down. This is set aside for twelve
hours, washed by decantation with hot water till free o
118
PHARMACEUTICAL JOURNAL.
[Feb. 6. 1897
chloride pressed, dried at 100° C. till constant, and weighed. This
method gives good results, and has advantages over the other two.
The manipulation is much simpler, no combustion or sulphuretted
hydrogen apparatus being required. The method should recom¬
mend itself to retail pharmacists, as it could be performed at the
dispensing counter without much experience in manipulation, and
it meets that desideratum in a pharmacy of being cleanly. It may
be noted that while the Pharmacopoeial standard is 77 '5 per cent,
of metallic mercury, none of the samples reached this amount, the
highest being 76 '8 per cent. — A most exhaustive and interesting
lecture was then delivered by Mr. George Senter on—
“The Chemistry of Sugars.”
In this he reviewed the history of the subject, and explained fully
by diagrams and experiments the various steps by which a know¬
ledge of the constitution of the sugars had been reached, and how
members of this important group of organic substances had been
produced synthetically.
School of Pharmacy Students’ Association, Friday,
January 22. — Mr. Bernard Jealous read a paper on the
Life of Robert Boyle.
Commencing with a brief account of the position of chemistry as a
science before the seventeenth century, biographical details con¬
cerning Boyle were then given, following which came an account of
his “ New Experiments, Physico-Mechanical, touching the Spring
of Air and its Effects,” and of the pump which Boyle called his
“ Pneumatical Engine.” The paper concluded with a detailed
and interesting statement of the position which Boyle occupies in
the history of chemistry.
Newcastle on-Tyne. — Wednesday, January 27. — A large
number of chemists met to discuss the desirabilty of forming a local
association. Mr. T. Maltby Clague was voted to the chair for
the evening and opened the proceedings by reading letters of
apology for absence and sympathy with the movement from Messrs.
B. S. Proctor, W. R. Riddle, G. Foggan, G. Weddell, W. Sarsfield,
J.P. , F. R. Dudderidge, and congratulatory letters from Mr. C. J.
Park, Plymouth, Member of Council of the Pharmaceutical Society,
Mr. A. H. Waddington, local secretary for Bradford, Mr. S. Norman
Pickard, Secretary of the Bradford and District Chemists’ Associa¬
tion, Mr. Harry Hutton, Leamington, and Mr. R. H. Bell, local and
associationsecretaryfor Sunderland. These cheery fraternal greetings
evoked much good feeling. Continuing, Mr. Clague emphasised
the need of association, and dwelt on the difficulties in the way of
the enterprise and the paramount necessity for some measure at
least of self-denying support for a common good. — After a free
and general conversation, all of which was favourable to the
scheme, Mr. Lancelot Arrowsmith proposed, and Mr. J. D.
Rose seconded —
“That an Association be formed for the advancement of scientific, educational,
and trade interests and the promotion of social intercourse.”
In the discussion which followed Messrs. Merson and Duncan
declared themselves against the too great prominence of scientific
subjects, and Mr. Kerse gave a historical summary of past efforts at
sustaining associations in Newcastle, and argued that the error
had been made of excluding trade topics. Ultimately the resolution
was unanimously passed on the terms above reported. It was
decided to admit to membership all registered chemists and drug¬
gists in the district and their assistants, and all wholesale druggists
and their employes ; apprentices of registered chemists to be
admitted to associateship.
The following officials were appointed : —
Secretary. — Mr. G. N. Merson, Newcastle.
Treasurer. — Mr. W. Kerse, Newcastle.
Vice-Presidents. — Mr. J. Robinson, Stanley ; Mr. A. E. Owen, Newcastle.
The Secretary was instructed to write and ask Mr. G. Foggan,
of Bedlington, to accept the position of President. The following
gentlemen were appointed on the Committee : — Messrs. Clague,
Rose, Weddell, Ridley, Peacod, Duncan, Milner, and Gibson.
Duboisine Sulphate in Paralysis Agitans.— Mendell and
Francotte have found the sulphate of duboisine to be a useful
sedative in paralysis agitans. From three to five granules, each
containing l/200th grain of duboisine, may be given each day, or
hypodermic injections of l/300th grain may be employed. — Therap.
(Jar.. [3], xii., 620, after Journ. des Practs.
LEGAL INTELLIGENCE.
PROCEEDINGS IN THE COURT OF APPEAL.
Milk of Sulphur Prosecution.
The case of Sandys v. Simpson came before Mr. Justice Wright
and Mr. Justice Bruce in the Divisional Court, on Monday last,
upon a case stated by the Justices of Heanor in the county of
Derby. It appeared that at the Petty Sessions held at Heanor
on October 26 last, an information was preferred by Henry Stair
Sandys against a chemist and druggist named David Osborne
Simpson, for that he (the respondent), did on August 18, 1896,
at Heanor, sell to one Joseph Hewitt, to his prejudice, a certain
drug, namely, “ precipitated sulphur,” which was not of the
nature, substance and quality of the article demanded by the
purchaser, in that it contained 46 per cent, of sulphate of lime.
The appellant, Mr. H. S. Sandys, is an inspector of
Weights and Measures for the county of Derby, charged
with the execution of the Sale of Food and Drugs Act, 1875, under
Section 6 of which the information was laid. When the matter
was before the Justices, on the charge being read over to the
respondent, he did not plead guilty or not guilty, but before any
evidence was given, admitted selling the article complained of,
namely, milk of sulphur, and stated that when he was weighing it.
he informed Joseph Hewitt that he had two preparations of the
article, viz., “ milk of sulphur” and “ precipitated sulphur.” The
respondent offered to change the article, and to supply Hewitt
with precipitated sulphur, which he designated as ‘ ‘ the pure,”
but Hewitt insisted on being supplied with the article that the
respondent was in the act of weighing, viz. , milk of sulphur, and
he was accordingly served with milk of sulphur. The respondent
further stated that milk of sulphur was a preparation he
had sold for forty or fifty years, and that it was what
his customers usually expected to be supplied with. He
also stated that it was his custom to keep pure precipitated
sulphur for medicinal purposes, but that he was seldom asked for it
and his customers had repeatedly returned it to him when supplied
to them, and asked that they might instead be supplied with milk
of sulphur, which was the article he (the respondent) at first
thought Hewitt required. The respondent further made the fol¬
lowing statement : “I rather sealed my own doom in that I used
a printed precipitated sulphur label without writing on it ‘ milk
of sulphur,’ but I had used up all the ‘milk of sulphur’ labels
a few weeks ago, and being in a hurry and not very well that day I
put this ‘precipitated sulphur’ label on in mistake.” It was
proved that Hewitt was the County Inspector and was at Heanor
on August 18, 1896. Hewitt, acting on the appellant’s direc¬
tions, that day went to the respondent’s shop and asked
for half a pound of precipitated sulphur. Hewitt duly notified
to the respondent his intention to have the article analysed by the
public analyst, and offered to divide it into three parts in accord¬
ance with Section 14 of the Statute, and duly divided it into three
parts, delivering one part to the respondent. The requirements
of the Statute were complied with, and upon one of the parts being
analysed by the public analyst it was found to contain 46 per cent,
of sulphate of lime. The appellant alleged that the article supplied
and sold by the respondent to Hewitt was not of the nature, sub¬
stance, and quality of the article demanded by Hewitt, who on
cross-examination denied the allegation that the respondent had
offered whilst weighing the milk of sulphur, or at any other time,
to supply precipitated sulphur, or to change it. The respondent
was not sworn, nor was any evidence called on his behalf. The
information was heard before four justices of the peace, and was
dismissed on the decision of the majority. The grounds of the
majority for dismissing the information were that the respondent
was well known to them as a most respectable and honest trades¬
man, and they fully believed his statement, notwithstanding the
evidence given by Hewitt.
Mr. Hextall appeared in support of the appeal.
The respondent was not represented.
Mr. Justice Wright said he should think very likely the Justices
were wrong in this case, but they had a right to go wrong if they
could reconcile it with their consciences. At any rate that Court
could not set them right.
Mr. Justice Bruce concurred.
Appeal dismissed without costs.
Feb. 6, 1897]
PHARMACEUTICAL JOURNAL.
119
CORRESPONDENCE.
A Panegyric — The Other Side.
Sir, — Mr. John Hick, of London, doubtless thinks he deserves
the thanks of all British pharmacists for his noble defence of Mr.
Martindale and his book, and especially for the example he sets in
regard to the “brilliancy” of his “logic.” His penultimate
sentence containing the remark aconitine was in the very best
possible taste. He is surprised at you, and not surprised at Mr.
Martindale. I am surprised at Mr. Hick. I should like to know
if he ever tried to make boroglyceride according to the very meagre
instructions given in the ‘ Extra Pharmacopceia,’ and I should
like to know what sort of a product he got. I have a great
respect for Mr. Martindale (that cunning artificer in drugs), who
is admittedly facile princeps as the exponent of elegant pharmacy.
I have a great respect for the ‘ Extra Pharmacopoeia ’ also. Many
a weary search through back volumes of the Pharmaceutical Journal
and the Chemist and Druggist has that most excellent and com¬
pendious pharmaceutical cyclopaedia saved me, but we cannot get
.away from the fact that the working details it. gives for the pre¬
paration of boroglyceride are inadequate. Now let us look into the
matter in a slightly more logical manner than Mr. Hick has
done. Mr. Martindale is hurt at a certain remark,
namely, “ You must not look upon Martindale as an
infallible guide, or you may be led astray.” Readers will no
-doubt have noted the cautious courtesy of the answer, ‘ ‘ you may
be led astray,” not “you will be led astray.” The contingency of
being led astray is a corollary to the assumption of infallibility, so the
matter resolves itself into the infallibility or otherwise of “ Martin-
dale.” Mr. Martindale in his letter, ante p. 80, says: — “I am
not infallible, but I hold that the ‘ Extra Pharmacopceia ’ is more
nearly free from errors than most works of the kind that have
been published,” a statement with which we all most cordially
agree. It will be observed that Mr. Martindale admits
his fallibility, ergo, there was no necessity for Mr.
Hick’s outburst of indignation, unless it were that he wished to
place on record another eulogium of the ‘ Extra Pharmacopceia. ’
I hope there is no slip in this train of reasoning, because it is
meant as an object-lesson to Mr. Hick, who has evidently let his
fetish worship run away with his logic. It must not be supposed
that I am endeavouring to emulate Don Quixote ; all that is in¬
tended is to give a fair show to an official who, after expressing
regret for inadvertently hurting someone’s feelings, has to submit
to have an innuendo slung at him as in the letter at p. 100.
Leith, February 1, 1897. George Coull.
Sir, — In your last issue Mr. Hick appears to say that we are
more indebted to Mr. Martindale for the information published in
the ‘ Extra Pharmacopceia ’ than to any other living pharmacist.
No doubt ; but in the same way one might say we are more
indebted to any other compiler for the information con¬
tained in his book than to any other living person. In either
case it seems to me one’s indebtedness to the mere com¬
pilers of the results of the labours of others is determined upon the
payment of the price demanded for their respective publications,
-and is an indebtedness of an entirely different order to that felt
towards successful workers in the domain of original research,
whether they hail from the laboratories of London, Germany, or
-elsewhere.
January 31, 1897. Borax (78/40).
Sir, — I have frequently been indebted to the staff of the Phar¬
maceutical Journal for the kindness they have shown in giving
information which from time to time I have had occasion to
require, and for the very evident trouble they have taken to make
that information as complete, explicit, and serviceable as possible,
and, personally, I was very pleased to see that in their reply to
Associate {ante, p. 60) re boroglyceride, they were not so overawed
by the “omniscience” of Mr. Martindale as to depart from what
appears to be their general rule. Mr. Hick, in his letter,
waxes sarcastic. It is, unfortunately, too often the habit
of great minds to treat with contempt the best efforts of their
lesser brethren, but he unbends in so far as to volunteer the
assertion that “ the present generation of pharmacists is more
indebted to Mr. Martindale for the information published in the
* Extra Pharmacopoeia ’ than to any other living pharmacist,”
from which dictum ordinary mortals may be allowed to differ.
Primarily, I should not think the ‘ Extra Pharmacopoeia ’
a book par excellence for chemists ; it devotes very little
space .to the modus operandi of preparations, whilst it
enters rather fully into therapeutical details : it presents a
large amount of information in a concise and handy form, though
the bulk of that is not, I should say, the outcome of original
work on the part of the author, but rather a resumd of the work
and observations of others ; how much labour is involved in verifi¬
cation, I know not. Comparisons are proverbially odious, and I
have no desire to be accused of throwing dirt at my superiors, but
I am conscious of no feeling of gratitude towards the ‘ Extra Phar¬
macopoeia ’ that would lead me to ignore the fact of our great
indebtedness for present knowledge of pharmacy, to the work
of Attfield, Ince, and Proctor, to that reliable friend Squire’s
‘Companion,’ and also to the pages of the Pharmaceutical Journal.
February 2, 1897. Free-Thinker (78/41).
The Benevolent Fund.
Sir, — I have read with great interest in this week’s Journal Mr.
Kemp’s appeal on behalf of the Benevolent Fund. Apart alto-
together from the reason put forth for a special effort being made
this year, I do not think (die Fund receives the support it ought to
from the body of chemists and druggists throughout the country ;
but when an occasion, such as is now approaching, affords the
opportunity, there is every probability of an appeal receiving more
support than when made under ordinary circumstances. We sub¬
scribe willingly to funds having for their object the relief and
assistance of harassed and unfortunates away from our shores, why
should we not more willingly give what we can to support and help
those of our own calling who, perhaps, through no fault of their
own, have had to drink the bitter cup of adversity ? That some
organised plan would be the most advantageous goes without say¬
ing. For a meeting to be called and a resolution passed, agreeing
“ that a general united effort be made all over the country to place
the Fund on a secure basis, and that all local secretaries be asked
to co-operate in the work,” might serve the purpose. I am quite
satisfied a great response would be the result of such an
appeal, and that local secretaries all over the country would do
their best to celebrate in this fashion the “Diamond Jubilee
of our Gracious Queen.” Some such idea would receive the
support of —
February 2,1897. William L. Currie,
Local Secretary for Glasgow.
Sir, — Mr. Kemp’s appeal for a special effort this year in the
interest of the Benevolent Fund cannot but meet with very general
approval. It is not unlikely that the Council contemplate some¬
thing of the kind, and I am sure that those engaged in local
secretary work throughout the country will do their utmost to
augment this most deserving Fund. It is not my intention to
discuss Mr. Kemp’s scheme, but to support him in urging the
desirability of adopting some special means this memorable year
of adding to the capital of the Fund, or of providing a surplus to
enable the Council, for a few years at any rate, to give relief in a
greater number of cases to others than annuitants. Whatever
plan — having this object in view — may be agreed upon will, I am
convinced, meet with hearty support and co-operation.
Liverpool, February 2, 1897. Jno. Smith.
Sir, — I have great pleasure in endorsing all Mr. Kemp says in
his appeal for aid to the Benevolent Fund, and I hope he will
stick to his text till it is carried out. But there is another thing
the Society may do in this sixtieth year of Her Most Gracious
Majesty’s reign — that is, by an act of grace put the chemists and
druggists who hold the Modified certificates on the same footing in
relation to the Society as those of their brethren who
were in business before the passing of the Pharmacy Act,
1868, and so remove the one thing which makes the
Society so unpopular amongst us who hold that quali¬
fication. This need not cause any jealousy amongst our Minor
brethren, as they can, if they like, go in for the Major, and so
become pharmaceutical chemists as well as members'. Not so wuth
us ; the “ First,” Minor, and Major examinations form an impass¬
able barrier against it. It may not be generally known that the
youngest modified man must be close upon fifty years old, as the
Act fixed the age for the Modified examination at 21 years in 1868,
and as that is 29 years ago I cannot be far out on that point.
If the Society have not the power to do this of themselves, I
feel sure if there is a member on the Council who has any
sympathy with us, he will have but little trouble in
120
PHARMACEUTICAL JOURNAL,
[Feb. 6, 1897
bringing the matter before her Majesty’s Privy Council and
getting their consent to it. It cannot be thought that a lot of
men who have been in the business for thii'ty years, and are now
getting grey from old age, would be other than an acquisition to
the Society. Anyhow, I trust that this, the dream of my life,
will not be allowed to pass unnoticed, and that before this memor¬
able year of Her Majesty’s reign has passed away, I shall be a
member of the Pharmaceutical Society of Great Britain. It seems
strange that the Secretary should still announce that the Board of
Examiners will meet to conduct the Modified exam. Surely there
are no candidates at fifty years old.
February, 2, 1897. A Modified Man (78; 37).
The Keeping Qualities of Essence of Lemon.
Sir, — It may interest most of your readers and all those who are
oncerned in the sale or use of essential oils in general, and of
essence of lemon in particular, to know that the long-
credited belief that any essence will go “ turpy ” after the
first season or so is absolutely unfounded, as far as it
applies to the pure and natural article. Like everyone
else we had no choice but to give credence to these
erroneous assertions, so much so as they were corrobo¬
rated year after year by our personal experience ; indeed, the
representatives of some Sicilian houses go so far as to assure us
that the purer the essence of lemon the sooner it will turn “turpy” !
This, however, is not confirmed by the results of our lengthened
investigations, and we are now in a position to prove that pure and
natural essence of lemon, such as is extracted from the
fruit, can be kept good and fresh under proper conditions,
namely, the exclusion of air, light, and heat, for
at least three years, and that it is only the spurious and
adulterated article that will sooner or later become “ turpy,” the
lapse of time depending upon the extent of the adulteration. We
shall be pleased to fully satisfy any of your readers that essence of
lemon extracted in 1893-4 and in 1894-5 has kept to this day
perfect in aroma, flavour, and odour, without any smell of turpen¬
tine whatever. The two parcels just referred to have been, since
their landing (and are still) under official control : which circum¬
stance is of itself conclusive evidence of the truth of our statement.
London, February 3, 1897. Typice and King.
The Journal and its Students’ Page.
Sir, — Kindly allow me to add my testimony to many others to
the excellent “Students’ Page” introduced recently into the
Journal. Every student will, I am sure, find it a great boon,
especially that portion dealing with the study of the B. P. , explaining
as it does the why and wherefore of the different processes of the
B.P. Those who have done the Minor will, when reading it,
doubtless wish that it had appeared in their students’ days, but
will read it nevertheless with no less interest. As one of your
correspondents remarked, no student can now say there is nothing
to interest him in the official organ.
Exeter, January 31, 1897. F. S. Hickman.
Sir,— The “Students’ Page” has been a happy hit, and is
widely appreciated. If you would consider favourably, and adopt
the suggestion of your correspondent “Qualified,” to devote some
space to the “Major” studies, you would add to the obligation of
your readers. A series of notes systematically arranged would be
useful, not only to “Major” students, but to many others who
desire to refresh or increase their knowledge of the subject. If
the “Major” could be taken at two separate examinations, I am
sure it would have far-reaching and beneficial results to the trade
and in loyalty to the Pharmaceutical Society.
Liverpool, February 2, 1897. Jno. Smith.
PUBLICATIONS RECEIVED.
Lean’s Royal Navy List for January, 1897. By Lieut. -Colonel
Francis Lean. Pp. 476. Price 7 s. 6 d. London : Witherby
and Co., 326, High Holborn, W.C. 1897. From the Publishers.
Kelly’s London Medical Directory for 1897. Pp. 542. Price
6s. 6 d. London : Kelly and Co., Limited, High Holborn, W.C.
1897. From the Publishers.
Exposures of Quackery. By the Editor of “Health News,”
2 vols. Is. each. London : The Savoy Press, Ltd., 115, Strand,
W.C. From the Editor.
ANSWERS TO QUERIES.
[Queries addressed to the “ Editorial Department , 17, Bloomsbury Square, W.C.,"'
will be replied to in the Journal as early as possible after receipt, but the Editor
cannot undertake to reply to them through the post, nor is it always possible to publish
answers the same week. Questions on different subjects should be written on separate
slips of paper, each of which should bear the sender’s name or initials. Readers
requiring working formulae for special preparations, and intimating their wants to the.
Editor, will be assisted as far as may be practicable. The word “parts," when used in-
formulae, invariably indicates parts by weight. Anonymous queries will be ignored .]
Specimen Identified.- — It is a specimen of Selagiuella Jcraus -
siana, A. Br. — [Reply to A. R. — 74/44.]
Acid. Phos. Conc. — The note in your interleaved B.P. is un¬
doubtedly incorrect. \Reply to S. H. — 78/33.]
Sale of Cocaine. — -As a poisonous vegetable alkaloid cocaine
must be treated in accordance with Part I. of the Schedule of
Poisons. \_Reply to Cocaine. — 78/23.]
Ball Report.- — The report — which by the way you do not quote
quite correctly, as the gentleman you name is not described ther e
as honorary secretary — appeared as furnished to us. Early intima¬
tion of the event appeared in our pages, and we are informed, on
making inquiries with regard to your complaint, that four
hundred circulars were sent out locally. — [ Reply to John Onion.],
Water Gas.- — This gas is prepared by passing steam over heated
coke kept at a constant temperature. As a result a mixture of
hydrogen and carbon monoxide is obtained, and this is passed
through petroleum spirit to make it yield a luminous flame.
[ Reply to A. W. H. — 77/40.]
Micro-Photographs. — These are simply ordinary positives, so-
minute in size as to require the use of a lens or microscope to
render their details visible. The pictures photographed, instead
of being simply reduced to some standard plate size, are reduced to a
very minute degree. They must be taken by the collodion process,
on a fine-grained film, and what especial difficulty there is arises in
connection with the operation of focussing the image. There is no
special book on the subject. {Reply to Micro-Photo. — 77/23.]
Several letters and answers to queries are unavoidably held over
and some anonymous correspondents are referred to the notice at'
the head of this column. Other communications ha ve been delayed i
through being addressed to 5, Serle Street, instead of 17,
Bloomsbury Square, and others again are written on both sides of
the paper, contrary to our rule.
OBITUARY.
Nind. — On January 26, at Wandsworth, George Nind, Pharmaceu¬
tical Chemist and Member of the Society. Mr. Nind’s connec¬
tion with the Society dates from the early forties, and his-
loyalty to its interests endured throughout life. He had for
several years occupied the position of Divisional Secretary for
the Parliamentary Division of Wandsworth, and was pleased to
have the opportunity of showing his deep interest in pharmacy
by the performance, con amore, of the services connected with
the position. There was about Mr. Nind an old-world spirit of
devotion to the craft, and loyalty to those who were working for
its advancement, which commanded the respect of all those who.
knew him. It may interest pharmacists to know that the
Society was indebted to Mr. Nind for a water-colour sketch of
Jacob Bell’s house at Clapham — the Old Clock-House — and for
other souvenirs of the former residence of the ‘ ‘ Member for
St. Albans.” Aged 78.
Burn. — On January 27, at 460, Collyhurst Road, Thomas Burn,
Chemist and Druggist. Mr. Burn was an .Associate of the
Society, with which he had been connected for more than twenty-
five years. Aged 51.
Hunt. — On January 27, William Hunt, Pharmaceutical Chemist,
of Camberwell Green, S.E. Mr. Hunt had been a member
of the Society since 1853. Aged 68.
COMMUNICATION S, LETTERS, etc., have been received from
Messrs. Ashton, Austen ; Blythe ; Clague, Coull, Currie ; Davies, Dennis, Dodridge,
Duyk; Evans; Fidden ; Hampson, Hartness, Hickman, Hill, Hogg; Jones;
Lindsay; Miller, Moss, Myers; Nursaw; Oldham, Onion; Reynolds, Reeve.
Robins; Sargeant, Scupham, Smith ; Thomson ; Umney; Wyatt.
Feb. 13, 1897]
PHARMACEUTICAL JOURNAL.
121
THE OINTMENTS OF THE B.P.
BY E. W. LUCAS.
The directions for the preparation of several of the official oint¬
ments not yielding very satisfactory results, I was led during the
autumn of last year to commence a few experiments with a view to
their improvement. It is not proposed, however, in this short
paper to deal with each ointment separately, except in one or two
instances.
The ointments may be divided into two classes: — (A) Those con¬
taining medicaments intended for absorption, such as aconitine ;
(B) those used as dressings for wounds or sores, of which boric
acid ointment may be taken as a type.
Class A requires a basis having a melting point about 95° F. ,
capable of being readily absorbed when rubbed into the skin, and,
while having well-marked preservative properties, free from any
tendency to set up irritation.
Prepared lard containing 3 minims of oil of cloves to each ounce
is suggested as fulfilling all the conditions enumerated. This basis,
which might be called adeps odoratus, is a whiter preparation than
the official benzoated lard, blander, and endowed with better
keeping properties.
Class B also requires a non-irritant basis, the melting point of
which should not be lower than 115° F., so as .to avoid the in¬
convenience caused by the ointment softening and soaking into the
bandages, and not higher than 120° F. , on account of the difficulty
experienced in spreading very hard ointments on lint, etc.
A mixture of solid hydrocarbons completely liquefying within
the limits of temperature before mentioned would appear to be the
most suitable for the purpose, and such a mixture might be known
as unguentum petrolei or unguentum simplex. Following out
this, the ointments might be classified as follows : —
Class A.
*Ung. Aconitines . 2 per cent.
* ,, Atropinse . . . 2 ,,
,, Belladonnae . — . . 10 ,,
,, Chrysarobini . 5 ,,
,, Gallse „ _ . 20 ,,
„ „ c. Opio . . . 10 ,,
„ Iodi . 3 „
,, Potassii Iodidi . 15 „
,, Staphisagrise ...._ . 33 ,,
* ,, Veratrinae _..... _.... .. 2 ,,
* Ung. Aconitine s, Ung. Atropince, Ung. Veratrince. — These ointments should be
made to contain 8 per cent, of oleic acid, in which the alkaloid may be dissolved
by aid of gentle heat.
Class B.
Ung. Acidi Borici . . .
15 per cent
*
11
Acidi Carbolici .
5 „
11
Acidi Salicylici . . . _
4 „
11
Calaminse . . . . .
10 „
n
Cantharidis ...... . . . . . .
15 „
11
Eucalypti .
10
11
Glyc. Plumbi Subis . . .
10 „
it
Hydrarg. Ammon . . .
10
it
„ Iodid .
5
it
,, Nit. Dil .
33 „
1 J
,, Ox. Rubri . . .
10 „
3)
,, Subchlor . .
10
n
Iodoformi .
10 „
11
Plumbi Subacetatis .
5 „
11
,, Carbonatis . .
10
It
j j Iodidi • •*■»••••»»«••• • • • • • •
10 „
11
Sulphuris .
10
11
,, Iodidi .
5 »
11
Zinci .
15 ,,
11
Zinci Oleati . .
50 „
* Ung. Acidi Carbolici. — If an equivalent quantity of liquefied carbolic acid,
containing 10 per cent, of water, is used, there is less tendency to crystallisation
on keeping. Glycerin would do, but requires a larger quantity for solution of
the acid.
Vol. LVII1. (Fourth Series, Vol. IV.). No. 1390.
The ointments not included in the above list are those of
spermaceti, mercury (simple and compound), mercuric nitrate,
tar and resin. These may be prepared as follows
Unguentum Cetacei.
Take of—
Spermaceti . 1 part.
Soft White Paraffin . 4 parts.
Melt and stir until cold.
Unguentum Hydrargyri.
Take of—
Mercury . . . . . 1 part.
Anhydrous Wool Fat . 1 part.
Stir together until mercury globules are no longer visible to the naked eye.
Note.— As this ointment is largely used for inunction, the change would be
found advantageous.
Unguentum Hydrargyri Nitratis. — The directions for this oint¬
ment should read as follow : —
Dissolve the mercury in the nitric acid without the aid of heat, agitating
gently from time to time. Melt the lard in the oil and raise to a temperature of
about 380° F. Pour into an earthenware vessel previously made hot, capable of
holding ten times the quantity, and when the mixture has fallen to about 350° F.
add by degrees the cold mercury solution, stirring briskly with a wooden spatula
to promote disengagement of the fumes. Keep stirred until cold. If these
directions are closely followed a pale lemon-coloured ointment will result, which
only acquires a slight orange tint, even after keeping for several months.
Much controversy has taken place regarding the preparation of
this ointment, but I feel emboldened to write with a certain amount
of confidence on the matter, as the firm of John Bell and Co. have
had a considerable reputation ior its manufacture for several
generations. In fact there hangs in the counting-house in Oxford
Street an engraving, published in 1842, of a water-colour drawing
by W. Hunt, representing the interior of the old laboratory, with
a porter named Simmons as the central figure, actually engaged in
stirring a batch of nitrate of mercury ointment, as witnessed by
the label. It is moreover traditional that the same J ohn Simmons
was permitted by Jacob Bell to take a fee of half-a-crown from
each assistant whom he initiated into the mystery of making the
ointment.
Unguentum Picis.
Take of—
Stockholm Tar
Hard Paraffin . .
4 parts.
1 part.
Melt together and stir until nearly cold.
Unguentum Besince.
Take of —
8 parts.
4 ,,
Hard Paraffin .
Soft
3 ,,
15 „
Melt the resin, yellow wax, and hard paraffin ; add the soft paraffin, and stir
until cold.
KINKELIBAH.
Inquiries have been made of late concerning an African
remedy bearing the above name, and which has been stated to be
“ the only good remedy for the hsematuric bilious fever which is so
fatal to Europeans in West Africa ” (Public Opinion , August 9,
1895), but which seems to occur equally in Eastern Tropical Africa,
where it is desired to try the value of the remedy. In Public
Opinion kinkelibah is referred to Combretum glutinosum, Guill. et
Perr., but by Dr. E. Heckel, in 1891, it was referred to a new
species, Combretum raimbaulti, Heck. (B Apert. de Pharm., 1891,
p. 216, fig. p. 252). From his description of the plant the following
account is taken : — •
The name kinkelibah is used by the Susa people, from Rio
Nunez to the neighbourhood of Sierra Leone. By the Woloft
122
PHARMACEUTICAL JOURNAL.
[Feb. 13, 1897.
people it is called “sekhaou” and “ khassaou,” and sometimes
“ lakhass. ”
It is abundant in the Rio Pongo district, and is found in
Dubreka and Mellacore, but does not seem to occur at Sierra
Leone, although found opposite to Free Town. It occurs also in
the Island of Conakry, and abundantly on the plateau of Thies>
on the railway from Daka to St. Louis, preferring stony and sandy
ground near the rivers, but never occurring on marshland reached
by salt or brackish water. It flowers in May and June (which is
probably the best time to collect it). The stem attains a
decimetre in diameter, and at this age the trunk becomes
white, and is thus easily recognised amongst the surrounding trees.
The leaves are used in the form of decoction made by boiling four gr.
of the leaves (one drachm) in 250 gr. of water (about eight ozs. )
for a quarter of an hour in a covered vessel. The resulting liquid
should be of a clear yellow colour and bitter ; if it is brownish
t is too strong and must be diluted until the yellow colour is
obtained. The above quantity is a single dose, and should be
taken at the onset of the attack ; half the dose should be re¬
peated in ten minutes, and again after the lapse of another ten
minutes. The vomiting produced soon stops, and then ceases
altogether. The decoction is taken during four days in a quantity
not exceeding 1| litre per day. No food should be taken whilst
the eyeballs remain of yellowish colour, which usually lasts for
three days. On the fourth day very little nourishment of a light
character at frequent intervals should be given. M. Raimbault
gave raw eggs beaten up with brandy or rum.
If the bowels are confined during the attack a purgative is given
with advantage. On the fourth day 80 centigrammes (about 12
grains) of sulphate of quinine are given together with the
kinkelibah, and the dose is diminished every day, whilst the
kinkelibah is continued so long as there is gastric trouble of a
bilious character. It is recommended to Europeans to take a
glass of the decoction every morning fasting, as a means of
acclimatisation. In a paper published in the ‘ Notizbl. des Konigl.
bot. Gart. und Mus. zu Berlin,’ June 10, p. 151, by Professor A.
Engler, the kinkelibah is identified as Combretum cdtum, Guill. et
Perr, which is also identical with G. micranthum, G. Don. He
remarks that it is easily recognised by its small flowers and four
winged fruits only eight m.m. in diameter.
The plant was recently found by Mr. G. L. Scott-Elliot on the
laterite hills behind Sierra Leone, at an altitude of about 600
metres. It is therefore easily obtainable, and if its reputation proves
to be well founded, it would be worth cultivation in the eastern
districts of Tropical Africa. Professor Engler suggests that it is
worth inquiry whether the somewhat similar species occurring in
East Africa are likely to produce the same remedial effects. These
species are G. brunneum, Engl., in Djurland, and C. schwnanni in
Buiti. The examination of kinkelibah by Prof. Schlagdenhauffen
showed it to contain 20 "80 per cent, of tannin and potassium
nitrate, but no constituent likely to stop vomiting was detected.
Sodium Tellurate as an Anti-Sudorific in Phthisis. — By
destroying the toxines which provoke perspiration, tellurate of
sodium, according to Joguet and Neisser, acts as an efficient anti-
sudorific. The initial dose of the salt is 2 centigrammes per diem,
which may be gradually increased to 5 centigrammes if benefit is
not obtained with the smaller dose. It should not be given above
this dose, or digestive disturbances may result. It may be given
in pills or in the following mixture : — Tellurate of sodium, 10 to 20
centigrammes ; alcohol, 50 per cent. , 50 grammes ; a teaspoonful
to be taken morning and evening in sweetened water. — Rev. de
Therap., Ixiii. , 629.
PRACTICAL RADIOGRAPHY.
IV.— THE CROOKES’ TUBES.
We now come to the consideration of the Crookes’ tubes for
radiography, and it is as well that we should consider first the
question whence come the X rays ? It is acknowledged generally
that when a tube is exhausted, the positive or anodic discharge
will follow all the windines or turns of the tube till it reaches the
cathode. This is well
shown by a very pretty
experiment of Crookes
and confirmed by
Bertin, and which is
shown in Fig. 1. In
this it will be seen that
the three positive elec¬
trodes or anodes + being
connected with the coil,
give off three dis¬
charges which, irre¬
spective of the position
of the anodes, curve
round to the cathode.
On the other hand, the
this case from a concave surface, proceed
in straight lines which, crossing or coming to a focus again,
diverge, as shown in Fig. 2. Now, it is obvious from this that
the cathode discharge obeys to some extent the ordinary laws of
light, and therefore we have to consider these, and supposing
we assume our cathode to be a reflecting surface we have
in the case of a plane cathode each point of its surface prac¬
tically a source of a rectilinear wave or propagation, and
consequently we get a diffusion or divergent beam, just as we
Fig. 1.
cathode discharge in
\
get with a fairly large source of light, and therefore we get
parallax. If, however, we use a concave cathode we have following
the well-known laws of light an actual focus F in Fig. 3 from
which again we get divergent rays. If now we place at the focus
of the rays a plane surface, we shall have rays given off according
to the well-known law that the angle of reflection is equal to the
angle of incidence, and it is now generally acknowledged that the
X rays have their origin in the anti-cathode surface, which may or'
may not be the anode. We may represent the path of the rays by
Fig. 3.
The forms of tubes differ a great deal, but it has been proved
that the so-called “ focus ” tube gives the sharpest results. In
Fig. 4 will be found a very large number of tubes, this diagram
having been copied from Nature , and of these the only ones we
need note at length are No. 1, the original form of Crookes’ tube
and No. 32 Rontgen’s tube, many of these tubes are of more
value for experimental show purposes than for radiography, as they
Feb. 13, 1897.]
PHARMACEUTICAL JOURNAL.
123
do not all give equally sharp definition either on the photographic
plate or fluorescent screen.
Dr. Eder, of Vienna, has been trying some special forms of
tubes, and one in particular made by Greiner and Friedrichs, of
Stutzerbach, has been specially designed for fluorescent screen
Forms of tube used for the production of kathode and X-rays. 1, 2, Crookes
tube ; 3, S6guy tube ; 4, Wood tube ; 5, S6guy tube ; 6, Chabaud and Hur-
muzescu tube ; 7, S6guy tube ; 8, “ Focus ” tube ; 9, Seguy tube ; 10, d’ Arson val
tube ; 11, Seguy tube ; 12, Puluj tube ; 13, Seguy tube ; 14, d’Arsonval tube ;
15, Le Roux tube ; 16, 17, 18, Seguy tubes ; 19, Rufz tube ; 20, Crookes’ tube ;
21, 22, 23, S4guy tubes ; 24, Rontgen tube ; 25, Brunet-Seguy tube ; 26, 27,
*Le Roux tubes ; 28, Colardeau tube ; 29, Seguy tube ; 30, Colardeau tube ;
31, S6guy tube ; 32, Rontgen tube. — Illustration reproduced from Nature
work, and is constructed of black manganese glass with a white
glass window, Fig. 5, the idea of this being the suppression of the
fluorescence of the glass, which is troublesome. Eder and Valenta,
who have carried out a series of exhaustive experiments on radio¬
graphy, use a spark gap in the connection to the tube as shown in
Fig. 6. Another very quick acting tube is that shown in Fig. 7,
made by H. Frister, 23, Lindenstrasse, Berlin S. W. ; another good
form which may be used with
any kind of generator, is
Fig. 8, and either one or both
concave plates may be the
cathode. W. Watson and Son,
of High Holborn, have intro¬
duced a form of tube which they call the “ Penetrator,” Fig. 9,
which gives unusually clear and brilliant results, and one of the
principles of its construction is said to be the employment of a
small quantity of metal, which occludes any residual gas, the
vacuum being thus controllable, but its efficiency is also probably
due to the peculiar form of the anticathode.
For lecture experiments, Puluj’s tube shown in Fig. 10 is ex¬
tremely taking, as it contains a screen of mica covered with a
fluorescent material which glows with an intense blue luminescence ,*
its efficiency for screen and photographic work is not so great as
others, and it could possibly be improved by making the cathode
concave of small radius.
A few hints, possibly, as to the best method of using the Crookes’
tube may not be out of place, and they should be held by means
of a Wolff’s holder, and the
wires from the coil should
be coiled spirally so as to
form fairly resistant coils,
and not be allowed to touch
each other, the tube, or
table, as otherwise the spark
will for preference take the
path of least resistance in
preference to going through
the tube.
It is advisable when pur¬
chasing Crookes’ tubes to
always state the length of spark that the coil will give, because it
is possible to obtain a vacuum so high that the electric current,
cannot pass, and therefore no X rays will be generated. And by
use the vacuum is always increased, and therefore a tube which has
been working well may by constant use emit less of the X rays. The.
simplest way to tell whether a tube is working well is to examine
the discharge within the tube, and outside with a fluorescent screen,
in the latter case noting the distance from the coil at which the
screen luminesces. In the interior of the tube the slightest trace
of blue colour proves that the vacuum is too low. It is possible
to improve a tube very much when the vacuum is low by the
following plan. Connect the tube up to the discharging points of
the coil, separating these by about an inch, and switch on the
current. Possibly the spark will leap across the air gap between
the dischargers, in preference to going through the tube ; if it does-
not the tube must be worked till the spark does pass between the
discharging points. This means that the vacuum has been raised
Fig. 5.
124
PHARMACEUTICAL JOURNAL.
[Feb. 13, 1897
Fig. 9.
til] the spark will the more easily pass through the dischargers
than the tube. If the spark passes readily between the dischargers
at an inch, separate them slightly till the spark goes through the
tube, the distance be"
tween the dischargers
may then be said to be
the expression of the
vacuum of the tube,
that is to say if the
distance is 3 inches the
tube is most suitable
for a 3 -inch coil. As
a rule it is advisable to keep on working in this way till the
spark will more readily pass between the dischargers when
separated by a distance of 4 to 6 inches than through the tube.
Care must be exercised all the time not to allow the tube to get
too hot and with the focus pattern, if the anticathode gets red hot,
the current should be switched off for a little time.
When by constant use the vacuum gets too high, the current of
electricity cannot pass through the tube, or only with difficulty,
and the result is that X rays are
generated only in small quantity.
The cause of this is supposed to be
the occlusion of the residual gas
by the electrodes or anticathode,
and this occurs more generally
when platinum is used than with
aluminium. The remedy for this is
to heat the tube with a spirit flame. An ordinary spirit lamp
should be used, but the flame should be a big one, at least four
inches in height, and the tube being held in a test-tube holder
should be rotated evenly and quickly in the flame, so that it gets
uniformly hot. A little experience is required as to the exact
degree of heating required, but as the tube can always be tested,
it is not a difficult matter. It has been stated that when the
vacuum gets too high it may be lowered by reversing the
direction of the current, but we have not found this so useful as
heating the tube.
The next article will treat of the fluorescent screen and plates
for radiography, and the series will conclude with the names
and addresses of wholesale firms from whom all the necessary
apparatus may be obtained.
Fig. 10.
POPULAR PHARMACY.*
BY J. C. HYSLOP.
( Concluded from page 10 f )
In practical matters, good pill-making and neat powder-folding
will ever serve as the outward and visible sign of the pharmacist’s
inward grace in the eyes of the British public.
It is piteous to see the badly -wrapped seidlitz powder, the loose
penny boxes of pills, the restful pharmacist merging into the
restless shopkeeper — handing over the counter his packages of
drugs bought by the gross, and folded in a loose and clumsy
manner by no one knows who. Epsom salts procured ready
packed are never clean, and as people usually want a dose only for
their penny, the packing of these at one’s own dispensing depart¬
ment will become one of the most economical and successful
advertisements that one could wish for. So may a penny
box of pills suffice to carry one’s name far and wide
if, added to a neat and not too wordy a label, the
contents be what in honour’s name they ought to be, so got
up as to proclaim its own peculiar nature as far as possible. Comp.
* Beport of paper read before the Chemists’ Assistants' Association.
rhubarb pills will always command a ready sale everywhere if the
smell of the English oil of peppermint pervades them, and if they
are not either too soft or too hard ; leave out half the proportion
of glycerin from the B.P. formula, and prepare sec. art., no pill can
beat this in the estimation of all classes. There is another popular
pill, the pil. rufi. This will never fail to command a good sale if
only the fair patient can see the nature of what she is taking, and
this is accomplished best by coating them with Martindale’s
varnish (gum juniper, 1 part ; absolute alcohol, 2 parts). They
must be prepared at your own pharmacy, follow strictly the B. P. ,
but dry the saffron yourself and powder it in a warm mortar, use
first-class myrrh, and reduce this to a coarse powder, and if good
friable “aloes socot.” cannot be got, use the watery extract, which
is not so liable to “give ’’with thermal and hygroscopic change,
keep the ‘ ‘ species ” ready mixed in a condition of coarse powder,
and when required to prepare a few dozen use, instead of treacle
and glycerin, the smallest possible quantity of simple syrup, beat
into a hard mass, to be at once divided into the requisite sized
pills and coated in the manner described in the ‘ Extra Pharma¬
copoeia,’ p. 352. If a “ chemist” means to secure popular favour
he must well cultivate the art of pill-building and decorating.
The less he meddles with sugar-coated or pearl- coated produc¬
tions the better, for all except in special cases his coverings should
be restricted to three, the merest sprinkle of lycopodium, silver leaf,
or sandarach, he., gum juniper varnish. If the sale of pills increases
so much that it becomes inconvenient to prepare them on the pre¬
mises, the wholesale pill manufacturers may be taken advantage of,
but if you fall into the trap of discontinuing the honest face article
for the white faced marbles that look and smell alike, and that
often will keep for ever in a patient’s inside as well as in your own
drawers — they are baked so hard in the manufacture — your pros¬
perity will dwindle away with no hope of recovery. The lotions
and other external applications should be well attended to.
Remember that what is intended to be applied to an open wound
ought to be every bit as unadulterated as what passes into the
stomach. Hence all lotions for patients, whether rich or poor,
should be prepared with distilled water, good and fresh, as well as
mixtures should. Carbolated oil must be prepared with pure oil
of olives and pure anhydrous carbolic acid. So must ointments be
prepared of the best ingredients and never stored in old porcelain
pots the insides of which are discoloured by long usage, nor when
being made neglected to be kept properly stirred until they are
really finished.
For these, amongst other reasons, we should prepare all the
ointments we possibly can, and those that must be purchased
ready made should be carefully scrutinised, both because the
public will keenly judge these if we do not, and also because of
the carelessness, amounting sometimes to fraud, allowed in their
preparation by unskilled hands, sheltered by the vulgar old notion
that they are only external applications.
To gain popular favour it is necessary to keep a good all-round
stock of packets of all things in general request that will not
deteriorate. But it is unwise to keep liquid preparations,
especially oils, and also certain dry goods ready packed, for people
Somewhat like, as a rule, to see the attentive, gingerly
man filling, corking, and folding before their eyes ; besides,
it is what grocers and stores cannot do, and we explain
to the people paranthetically the importance of all these
being freshly bottled, and when we have a chance we show
them the citrate of magnesia all gone wrong because it was corked
up tight in a bottle that had an infinitesimal amount of moisture
in a crevasse at the bottom, and you can explain blandly that of
course this was not handled by a chemist. It is for us as business
men to educate the public to a fairer estimation of our relations to
them. There is, as Dr. Rentoul has so well put, “A greedy public
with their debauched truckling for everything cheap, which should
not be pandered to ” ; but it is another and a better public
that we are called upon to woo in the interests of pharmacy.
As a business man, the pharmacist can be quite as cute and as
accurate in the keeping of his accounts as any man, without
climbing down to the level of a mere tradesman. He is not a
shiftless man, but one of ready resource, with fixed principles of
conduct, which he will find means of some kind for carrying out.
Is he somewhat lamb-like or sheepish in the eyes of many? Well,
let them look to it, for he can cultivate if needs be the cunning of
a fox or the wisdom of the serpent, and it is only by turning
traitor to his true connections and becoming thoroughly asinine
that he runs the least risk of being devoured by the lions and tigera
of commercial rapacity.
Feb. 13, 1897J
PHARMACEUTICAL JOURNAL
125
LIVING TISSUES AS CHEMICAL REAGENTS.*
BY ROBERT B. WILD, M.D., M.SC.
lion. Physician to the Manchester and Salford Hospital for Skin Diseases. Assistant
Lecturer on Materia Medica and Therapeutics in the Oicens College.
There are so many topics of mutual interest to the pharmacist
and the physician, that in choosing a subject upon which I might
address you — and I hope interest you — the difficulty was rather to
decide which of several tempting themes I should take up.
I felt, however, that to address an audience such as this upon
the pharmaceutical aspect of drugs would be only presumption in
me, while the purely therapeutic side of the question would only
weary you.
There seemed, however, a common ground upon which I might
venture to tread, and that is the borderland of physical and
biological science where chemistry and physiology meet, and
where it is impossible even now to say whether the phenomena
resented to us are entirely chemical phenomena, or whether we
ave something more; a “something” which the accumulated
knowledge of mankind has hitherto failed to elucidate, but to
which we apply the term “ vital ” as a cloak to veil our ignorance.
Our knowledge of the properties of living tissues is acquired
largely by experiments ; in these we submit the tissue to an
artificial environment, one or more factors of which can be altered
at will, and the effects of such alteration noted.
Amongst these variable factors not the least important is the
submitting the living tissue to the action of certain chemical
substances (or drugs) so as to study the effects produced, with a
view of obtaining a better knowledge of the manner in which drugs
act as curative agents in the treatment of disease.
It is to certain aspects of this experimental pharmacology that I
now wish to direct your attention. I do not pretend to any¬
thing more than to bring to your notice a few of the simpler
methods and instruments employed, the character and meaning of
the graphic records obtained by these methods, and to point out
the practical utility of this work in the study of the properties
of drugs, both new and old.
Where Chemistry and Physiology Meet.
As our knowledge of the physiological processes of living matter
becomes fuller and more exact, it becomes increasingly evident,
firstly, that the ultimate processes concerned in the growth, main¬
tenance, and decay of living organisms are chiefly, if not wholly, of
a chemical nature. Secondly, that those deviations from normal
physiological processes, which manifest their presence to us by so
many and various symptoms, and which we call disease, are in
most cases due to alterations in the normal chemical processes, or
to the introduction of new and abnormal chemical reactions.
Thirdly, that the use of drugs in the treatment of disease is in each
case a chemical experiment, in which a chemical reagent is intro¬
duced into the body for the purpose of restoring the abnormal
chemical processes of disease to the normal chemical processes of
health.
W e can illustrate this in the very simplest case when a man
swallows a quantity of a mineral acid and we administer the
chemical antidote — an alkali — to combine with the acid and render
it harmless. To take a step further, we know that without being
swallowed excess of acid may be present in the stomach from
changes taking place inside the body, and well-marked symptoms
of stomach disturbance are thereby produced ; we can often remove
these symptoms rapidly and completely with a dose of alkali just
as we did when the acid had been introduced from without.
To take another step, we know that under certain conditions a
complex organic acid — uric acid— whose chemical constitution is
well known and which is normally present in the body in small
quantities, is formed in large excess. The uric acid may be excreted
in the urine or arrested in the urinary passages, giving rise to the
diseased conditions known as gravel, stone in the kidney and stone
in the bladder, or the acid may combine with the soda of the blood
and form a salt, which, deposited in certain parts of the body, causes
those symptoms which we call gout. With the knowledge that the
potassium or lithium salts of uric acid are more soluble than the
sodium salt, we may treat these conditions successfully by giving
alkaline salts of lithia or potash which are then excreted in the
urine, combined with the uric acid which is thus removed from
the body.
In these processes of treatment we endeavour by means of
chemical reactions to remove injurious substances from the body
or to render them harmless after they have been formed. We are,
however, only treating the results of disease, and we may go further
back and try to strike at the root of the disease by preventing
their formation. This is the ideal of therapeutics, but to carry it
out we require to know how and where these abnormal chemical
substances are produced in the body. Very much of this know¬
ledge is still wanting, but each step we take brings us nearer to
the living cells of the individual tissues of the body or living
parasitic organisms contained in it, as the source during their
metabolic processes of these injurious substances. By metabolic
processes we mean the chemical changes in composition which the
living cell undergoes during its genesis, growth, functional activity,
decay, and death. Whether this living cell be a part of the body
or a parasitic organism, it absorbs certain substances from the
organic fluids in which all the tissues are bathed. These are
decomposed by the complex proteid molecule, to which, when
living, we give the name of “protoplasm,” and those products of
the decomposition not of use to the living cell are returned to the
surrounding fluid, and in many cases act as poisons to other cells
if not promptly removed or if abnormal in their composition. For
example, certain cells in the body may produce by their meta¬
bolism uric acid instead of urea from the nitrogenous ingredients
of the food, or the tetanus bacillus growing in the body may
produce a poison or toxin which acts upon the nerve cells in a
similar manner to strychnine.
Our information regarding the action of chemical substances ;
whether drugs, or toxins, or the normal constituents of the body,
upon the tissues is still very imperfect, owing to the difficulty of
experiment in these cases ; as a foundation for our knowledge we
require to reduce the problem to its simplest form and study the
action of our drugs, not upon the whole complex fabric of the
animal body, but first upon the isolated simple tissues, both in a
healthy and a diseased condition. This is what we are endeavour¬
ing to do by experimental pharmacology.
The Use of Tissues as Tests for Organic Principles.
In studying these subjects many side issues present themselves ;
one is the point upon which I wish to concentrate our attention
at present, viz., that the action of some chemical substances is so
marked and characteristic, and produces such constant effects
upon the living tissues, that we can use the tissue as a test for the
chemical substance itself.
This is true not only for simple things, but also for such complex
bodies as some of the alkaloids and other complicated organic
principles of active drugs, and the sensibility of the tissues is so
great that even the most minute quantities inappreciable to
ordinary chemical tests will produce their characteristic effects.
We all know that a thousandth part of a grain of atropine will in
some cases dilate the pupil of the eye for several days after its
introduction into the conjunctival sac, and a minute quantity of
anhydrous hydrocyanic acid will convert a healthy animal into a
corpse in a marvellously short space of time. That infinitesimal
quantities of other drugs are equally poisonous to simple tissues,
I hope to show you by a few experiments ; and the question is of
some importance, as it has been objected to the chemical view of
the action of drugs that the quantity introduced into the body is
too small to act chemically upon such an enormous mass of cells as
a human being.
In considering the reaction between a drug and a tissue, we may
measure the result in terms of the drug or in terms of the tissue.
For example, we may administer the drug and examine the ex¬
cretions to ascertain whether we can recover the drug in its original
or in a changed form, or whether some of it has been entirely used
up in the body, as, for instance, when we give benzoic acid by the
mouth and recover it from the urine as hippuric acid, or when we
administer a measured dose of alcohol and recover only a small
portion of it from the excretions, the remainder being accounted
for by the C02 and H20 produced by its oxidation. On the other
hand we may measure the reaction in terms of the tissue by noting
what effect a drug has upon the functions of the tissue under in¬
vestigation ; for this purpose only certain tissues are available, and
the most convenient is the contractile tissue, which lends itself
to experiment particularly well. The nervous, digestive, and ex¬
cretory tissues are also available, but are less easy to demonstrate
in the time at our disposal.
Of the contractile tissues we use three forms, the voluntary
muscle, the heart muscle, and the involuntary muscle, which sur¬
rounds the small arteries. Many animals may be used, but the
* Epitome of an address delivered to the M mchester Pharmaceutical Association.
126
PHARMACEUTICAL JOURNAL.
[Feb 13, 1897
frog and the tortoise are in practice most convenient, as in these
easily obtained cold-blooded animals the tissues live for a consider¬
able time after the animal is dead, and the risks and fallacies
which at times underlie vivisection experiments are avoided.
Recently killed, warm-blooded animals can also be used, but are
much more difficult to work with, and unsuitable for demonstra¬
tion experiments. [Several experiments were performed, showing
the action of various drugs upon heart, muscle, and vessels, the
tracings obtained from them explained, and diagrams exhibited,
showing the action of a number of drugs upon the tissues. The
various forms of apparatus used for the experiments were shown
and described. ]
I have tried to show you how we may utilise the vital properties
of living tissues as tests for the active principles of drugs, how, for
example, we may prepare from a crude drug, say a decoction, and
ascertain whether it contains any active ingredient ; if so, we may
proceed to separate this active constituent by the use of various
reagents or solvents, testing each step of the process by applying
the test of the living tissue, which will keep us informed as to
where our active ingredient is or whether it has been decomposed
or rendered inactive by our chemical operations. In this way we
may, I think, look for brilliant results in the future by the com¬
bined work of the scientific pharmacist and the pharmacologist.
The Growth and Extension of Bacteriology.
During the last fifteen years the discovery of the tubercle
bacillus by Koch has been followed by the rapid growth and
extension of the science of bacteriology and the relegation of one
disease after another to the class of germ diseases. In the early
part of this period we reached, I believe, the deepest depth of
scepticism regarding the therapeutic value of drugs. Indeed,
when it was believed that the germs directly caused the disease
it naturally followed that the only rational treatment was to kill
the germs. Now germs and their spores are very resistant
organisms, much more so than the more specialised tissues of the
higher animals, so that the problem of how to apply a drug so as
to destroy the disease germs without injuring the living tissues of
the patient appeared incapable of solution, in spite of the crowd
of new antiseptic drugs introduced with the hope that some might
have a selective action upon the germs. No other plan of treat¬
ment appeared likely to be of use, and therapeutics as an art in
these forms of disease seemed likely to be limited to hygienic and
expectant measures.
Since then, knowledge has increased, the germ no longer
occupies the same position. The chemical substances — toxins —
which are produced by the growth of the germs in an albuminous
soil are believed to be the essential factors in the production of the
disease. To illustrate my meaning, we may suppose a man to
drink a fermenting saccharine fluid and to become intoxicated ; we
■find that fluid to contain the cells of Toruli, the yeast plant, and
we may say that the yeast plant caused the intoxication ; this
would represent the earlier views of the action of germs. Later
on, we may find that the yeast plant produces alcohol from a suit¬
able, i.e., a saccharine, soil, and that the alcohol, and not the
yeast plant itself causes the intoxication.
This altered view of the mode of action of germs brings us back
to the belief in the utility of drugs, for it again introduces
chemical action as the pathogenic factor. The action of the
poison being chemical, drugs whose action is also chemical may be
useful in many ways, e.g., they may so alter the soil that the
metabolism of the germ no longer produces the toxin ; to illustrate
by our alcohol simile, they might so alter the sugar as to make it
unfermentable. Again, they may neutralise or decompose the
toxin so as to make it no longer toxic. To return to the alcohol, we
may conceive of its being oxidised to acetic acid. Or they may
so alter the composition of the tissues as to render them insus¬
ceptible to the poisonous action of the toxin. Here, again, we know
that in certain conditions of the body alcohol only produces
intoxication when taken in very large quantities.
These illustrations are, I think, sufficient to show that once it is
conceded that the disease-producing action of germs is chemical,
cur faith in the possibilities of drug therapeutics is restored.
At the present day we are passing through a phase of thera¬
peutic progress which seems to me to be essentially transitory in its
nature — a half-way house, as it were, between the pharmacy of the
past and the pharmacy of the future.
Animal Extracts and Antitoxins.
Two classes of drugs are attracting great attention, the extracts
from animal organs and the class of antitoxins. Into the nature
of these bodies I cannot here enter, but that we have in some of
them very active chemical substances no one can doubt who has
seen the effect of thyroid gland in myxoedema or the profound
bodily reaction which takes place in a tubercular patient who has
received a fraction of a milligramme of tuberculin. The question
arises as to the nature of the active ingredient in these prepara¬
tions. Is it alkaloidal ? Is it a ferment ? Is it an albumose ?
Much work has already been done and is doing, but I do not think
the problem is yet solved.
Until our knowledge increases we are compelled to administer
the crude substance, be it a thyroid gland, a pancreatic extract, or
the serum from the blood of a horse or an ass. This is not a satis¬
factory condition of things, first because the dosage is uncertain
and variable, second because we are giving many other substances
besides the unknown active ingredient, and some of these sub¬
stances may be positively injurious. We are, in fact, repeating
over again our experience with vegetable drugs before the dis¬
covery and isolation of alkaloids, glucosides, and other active
principles. What is required is experimental work on the isola¬
tion of the active principles in these animal extracts and anti¬
toxins, so as to avoid the uncertain and roundabout method of their
administration.
The great difficulty is the want of chemical tests and processes
by which the active ingredient may be identified. To produce a
satisfactory result the pharmacist and the pharmacologist must
work together. The former brings his chemical knowledge and
technical manipulative skill to separate the complex substance into
simpler ones, each of which in turn must be tested and identified
by its action on the living tissues. In this way, and I venture to
think in this way only, can real progress be made. I anticipate
in the future that we shall obtain substances as exact, certain, and
reliable in their action, and as convenient in their use, as the
vegetable alkaloids, which it is suggestive to remember are them¬
selves the products of the metabolism of vegetable protoplasm.
There is still one point to which I wish to refer, and it is that
the discovery and use of these new substances does not necessarily
lessen the importance of our older drugs of proved value, and
whose use at present rests so largely on empirical knowledge. For
if we suppose that an animal extract or an antitoxin produces a
definite chemical effect in the body, it by no means follows that no
other chemical substance will produce the same or a similar effect.
Should we discover and prepare from the parasite of malaria some
antitoxin which will prevent or cure ague, we shall probably find
that what we have gained is an explanation of the at present un¬
known mode of action of quinine, and it is quite conceivable that
quinine may still remain in practice the better and more convenient
remedy. Experimental inoculations of serum for the cure of
syphilis are already reported, yet I have no doubt that mercury will
still cure syphilis as well as it used to do, and may prove the better
and safer weapon.
The Pharmacist as a Biologist.
I have wandered somewhat from the strict text of may subject,
but I have done so in order to emphasise the fact that I believe
there is a great future before the profession of pharmacy.
Bacteriological work is not for the practising medical man, it is
work for which the training and education of the pharmacist
particularly fits him, and I do not see why he should not prepare
remedies from bacterial cultures as well as from the bark of
trees or the bodies of animals, or why he should not examine
a water for typhoid bacilli as well as a stomach for arsenic. In
order to take up this work the pharmacist of the future must be
more of a biologist than in the past ; he must not only look to the
test-tube, but also use the living tissues as his reagents, and to his
work in the future I look for the provision of accurate remedies of
definite power with which to cure or prevent disease, and convert
the art of medicine into the science of therapeutics.
Methyl Violet for Boils, Carbuncles, and Anthrax. —
Trenite has recently recommended the use of y3/3-metliyl violet for
boils, etc. Fifteen minims of a 2 per mille solution is injected into
the boil ; pain disappears in a few hours and cure is generally
complete in two days. Should true carbuncle or anthrax be pre¬
sent, the necrotic area should be slit open by means of a bistoury or
tenotome, and all necrotic matter removed before the injection is
made. The cavity is afterwards packed with iodoform gauze
which has been soaked in a solution of hot sodium chloride. —
Therap. Gaz. [3], xii., 615, after Journ. des Practs.
Feb. 13, 1897.]
PHARMACEUTICAL JOURNAL.
127
PHARMACEUTICAL SOCIETY.
DONATIONS TO THE LIBRARY AND MUSEUM.
At a meeting of the Library, Museum, School and House Com¬
mittee, held on Wednesday, the 10th inst. , the Librarian presented
the following report of donations : —
To the Library (London).
War Office : — Army Medical Department, Report for the year 1S95.
Koloniaal Museum, Haarlem Nuttige Indische planten, door Dr. M. Greshoff,
Afl. 3, 1896.
Messrs. T. and G. Peckolt, Rio de Janeiro : — Historia das plantas medicinaes e
uteis do Brazil, 6° fasciculo, 1S96.
Ecole superieure de pharmacie de Paris : — Des Acanthacdes medieinales, par G.
Dethan, 1896.
Pharmaceutical Society of Ireland : — Calendar, 1897.
The following donations were reported by the Curator
To the Museum (London).
Mr. L. Wray, Junr., Curator of the Museum, Perak : — Specimens of Castor Oil Seed
used in cooking by the Malays ; Gutta-percha from Dichopsis clarkiana :
specimen of “ Membuloh ” grass, used for flatulency.
Messrs. Schimmel and Co. : — Specimen of Cardamoms from Calcutta, “Camphor
seed ” ; wood, leaves and fruit of the West Indian Sandal- wood Tree ; Mexican
Lign Aloe Wood; Guiana Lign Aloe Wood ; Marapass (Roccella uiontagnei )
from Bombay ; and Mexican Valerian Root.
Mr. J. Moss, F.I.C., etc., London : — Specimen of stems of Cactus graadiflorus.
Messrs. Potter and Clarke, London : — Specimen of flower of Cactus graadiflorus.
Messrs. W. J. Bragg and Co., Liverpool : — Specimens of Sicupira Seed, Catuaba
Bark, and Fruits of Pilocarpus micropliyllus.
Mr. R, T. Baker, F.L.S., Technological Museum, Sydney Five packets of Seeds.
EVENING MEETING IN LONDON.
An evening meeting of the Society was held at 17, Bloomsbury
Square, on Tuesday last, the President, Mr. Walter Hills, in the
chair, and an illustrated lecture was delivered on
FOSSIL PLANTS.
BY A. C. SEWARD, M. A.
Mr. Seward said the subject of fossil plants must to a large
extent be a very dry and uninteresting one to the majority of the
audience, but the reason he had chosen it wras that it was a subject
on which personally he felt a great amount of interest, and there¬
fore he thought he had a better chance of interesting other people.
It had long been known that the remains of animals and plants
occurred in some abundance in the rocks of different ages which
went to make up the earth’s crust, but probably few were aware
of the real nature and extent of the science of fossil plants. In
comparatively recent years the study of fossil plants had become
a subject of some importance, and one which offered a very wide
field for further work and investigation for those who were minded
to take it up. He would try to give some very general view of the
whole subject, not attempt to describe anything in detail, but
rather to point out some of the general bearings and lines along
which those who were interested in the subj ect might attempt to work.
In the first place, he would try to give some general idea as to the
manner in which plants during the history of the earth had come
to be preserved in a fossil state embedded in the rocks which made
up the solid crust of the earth. At the outset some idea ought to
be formed of what the nature of a fossil plant really was, and how
it had come to be preserved as a fossil. He must begin by point¬
ing out very briefly certain facts familiar to many as to the way
in which the rocks composing the greater part of the earth’s crust
had been formed. To find out how certain things had happened
in the past, and arrive at the explanation of certain phenomena,
one must study what was going on before one’s eyes. The first
view showed a lake, into which had been carried a large
amount of different kinds of sediment. Naturally, as the river
flowed into a large sheet of water, and its velocity was checked, it
would deposit its burden of gravel close to the place where
it entered, and a little further on coarse sand, and
still further on it the lighter mud. In that way a large
amount of material was constantly being laid down on the
floor of the sea or lake ; all this material had been worn off
the surface of the ground. This constant wear and tear of the sur¬
face of the earth had been going on ever since the earth was suffi¬
ciently cool to allow water to remain on its surface. A great many
of the strata which made up the earth’s crust were nothing but old
sediments which were laid down on the floor of the sea or lake and
represented so much material worn off' the surface of the earth.
The Power of Running Water.
The next view shown on the screen was that of one of the canons
of Colorado, and illustrated the wonderful power that running
water had in wearing down the surface of the ground. A stream of
water running through a country clad with vegetation would carry
with it to its destination trunks of trees and all kinds of plants. Not
only would it carry down to the sea a considerable quantity of inorganic
matter, but also samples of animals and plants which inhabited
the particular region through which it passed. The fragments of
trees and plants carried by the water and embedded in the soil
in time formed the fossils of a future geological age. These fossils
embedded in the rocks were all that we had to tell us of the nature
of the vegetation and the animal life which existed during the
various epochs of the earth’s history. After the sediments he had
spoken of had been spread out on the floor of the ocean or lake
they became hardened and solidified and then upheaved above the
sea level. Some views were next exhibited of sections taken across
various parts of the country, mostly in the Alps, showing the magni¬
tude and the effects of some of the upheavals which had taken place.
It would simplify the illustration of his lecture if special attention
were paid to one or two particular periods in the history of the
earth. At the oldest periods of the earth’s history they found
certain rocks which contained no recognised remains of animals or
plants. Passing on they came to a great thickness of slate and
other kinds of rock, principally in Wales and parts of Scotland,
which contained the remains of the oldest plants and animals ;
and so passing on they came to the higher types of plants, till
finally they got at the very top to the first appearance of man.
Just a little lower than this they found the first appearance of
flowering plants ; so that flowering plants, like ourselves, were
organisms of quite recent growth. He wished to call attention
specially to the carboniferous rocks, because it was in rocks
at that stage of the earth’s history that they found the
best and most serviceable beds ' of coal ; and it was on
an examination of these rocks that they found by far the most
interesting examples of fossil plants. Some idea must first be
formed of what was meant when speaking of a fossil plant.
The Term “Fossil.”
The term “ fossil ” was used somewhat frequently in a loose sense ;
one heard the name applied to living human beings, but “ fossil ”
used in its scientific sense wras something which had been preserved
or embedded in the earth by natural means. It was not necessarily
something which had undergone any considerable change. One
sometimes associated the idea of a fossil with something that had
been turned into stone, but it was not necessarily so. In the fen
country, for instance, the remains of plants and stems of
trees which had undergone very little alteration indeed were often
dug up, and these were essentially fossils. The particular state
or condition in which a plant was found embedded in the ground
had nothing to do with its being a fossil or not ; it was essentially
a fossil as long as it had come there by natural agencies. Fossil
plants might be spoken of as being preserved by two methods,
either by incrustation or petrification. Incrustation meant that
the fragment of a plant had been covered up by some material,
and at a subsequent period the plant had decayed by natural pro¬
cesses and had left a mould embedded in the material which
incrusted it. Petrification applied to such cases as those in which
the substance of the plant had been actually permeated with some
preserving material, very frequently water containing silica or
carbonate of lime. As an illustration of fossils preserved by incrus¬
tation, a view of the dripping well at Knaresborough was displayed.
The water flowing over the bank into the well was charged with
carbonate of lime. When evaporation took place the water lost a
certain amount of its solvent power, and the carbonate of lime
was thrown down as a deposit. In that part of the country the
natives suspended various articles underneath the dripping water,
which very soon became covered over by the incrustation of car¬
bonate of lime. The substance of the various articles so suspended
— old hats, birds’ nests, and the like — soon decayed, but their form
remained. The next picture showed a piece of porous calcareous
rock, the same as at Knaresborough, having on its surface a number
of well-defined impressions of leaves, showing the central and
lateral veins. In this case the substance of the leaves
had been entirely removed ; all that was left was simply
[Feb. 13, 1897
128
PHARMACEUTICAL JOURNAL.
a neat impression of the leaf surface impressed on the surrounding
rock when in a soft condition. That was one of the forms in
which records of ancient plant life were preserved to them. It
very frequently happened that when, for example, the stem of a
plant, or any other part, was carried down by water it eventually
became water-logged and sank into a mass of sand or mud. After
a while the sand became somewhat hardened, and the piece of tree
trunk, or whatever it was, rotted away and left a hollow space in
the sand forming a mould. After a while sand was introduced
into the mould by running water, and in that way a cast was taken
in the sand of the mould. In other words, there was a perfect
reproduction of that form of plant in the sand. A view was next
show n of the cast of a huge root of a tree measuring from one
tip to another about twenty-nine feet. This fossil was found
some six or seven years ago in a stone quarry near Bradford, and
was of one of the trees which lived during the coal period. Impres¬
sions were also found of the external surfaces of plants, and an
illustration was shown of such a fossil found near Johannesburg.
Coal Seams as Records.
The coal seams themselves and the rocks associated with them
afforded a tremendous amount of valuable material, which had
rendered it possible to reconstruct with a considerable degree of
accuracy the vegetation which covered a large portion of the
Northern Hemisphere during the period when the forests grew
which afterwards became converted into coal. A map was then
shown displaying the various coal-fields in the United
Kingdom, including the recently discovered coal-field at
Dover. Some people were in the habit of speaking
of the study of fossil plants as a useless study, but
sometimes it was of extreme practical value. When
borings were made some years ago at Shakespeare’s Cliff, Dover,
core was brought up in which were fragments of fossil plants. It
was thought by some geologists that the coal contained in the fossil
plants that were brought up was probably coal belonging to some
recent geological period, and therefore of very little value. But
on examining them they were found to be exactly the same as
some of the plants of the typical coal-fields, and it was found
possible to exactly determine the age of the coal. An examination
of the characteristics of the common and better-known plants
which were in the forests forming the seams of coal afforded an
illustration that in some instances it was possible to study, not
merely their external surface, but sometimes to examine the
most minute internal structures with as much accuracy and
detail as in the case of the living plant. There was next shown
on the screen small spores, less than one-eighth of an inch in
diameter, which had been picked out with the needle from a piece
of coal. In some coal was seen little dots on the surface, which
when examined under the microscope was found to have the
form of spores of some of the extinct plants which grew in the
forests of the coal period, and some of them agree very closely
indeed with the spores of some of our living plants. On taking a
piece of coal from Bradford and grinding it down by means of a
special machine until it was almost transparent, one saw in some
of the sections a dark-coloured mass, and scattered through it a
number of bright orange-coloured lines which sometimes took
the form of compressed circles. On examining such a
piece of coal under the microscope it was found that the orange-
coloured lines were simply a number of spores of plants which had
been cut through, showing that the coal was very largely made up
of a mass of these spores. Anyone who had attempted to collect
fossil plants from the rubbish heaps of collieries in the North of
England must have noticed specimens which were apparently
stems showing a distinctly I’ibbed surface. When they were first
discovered, probably more than one hundred years ago, it was
thought that they had the impression of a stem which had its
surface marked by regular ribs and grooves. Comparatively re¬
cently it was found that the original opinion was quite wrong. In
the coalfields of Lancashire and Yorkshire are frequently found
hai’d pieces of calcareous rock lying about here and there in the coal
which on examination were found to contain a large number of
plant fragments which had been petrified, that was to say little
pieces of plants, the substance of which had been thoroughly
permeated by a solution of silica or carbonate of lime. By grind¬
ing down thin pieces from these hard nodules in the coal, and
examining these sections under the microscope, one found that the
plant tissues had been preserved in the most wonderful perfec¬
tion.
Microscopical Examination of Fossil Plants.
By applying microscopical examination to these plants a very
great deal had been made out with regard to the structure and
relationship of distinct plants. In many of these nodules found in
the coal there had been discovered twigs of branches showing a
characteristic structure. A diagram was shown of one of
these twigs as seen under the microscope. In the centre
was a wide pith, surrounding which there were a number of
projecting points, each of these being the inner end of a bundle
of woody tissues, each separated by a band of much more delicate
tissue. The bark of the twig had come off before the plant had
had time to become petrified. It was from specimens of this kind
that it was first discovered that the ribbed stems were not
impressions of the outer surface of the plant, but were simply the
casts of the hollow pith of the plant, the ribbed and grooved
appearance being simply due to the sand being pressed against
the concave space and the projecting ribs of wood
separating the more delicate bands of tissue. The delicate
bands would decay more rapidly than the hard parts.
This formed an illiistration of how the microscopical
study of petrified fragments threw light on these
specimens of plants, which were preserved only by incrustation.
This plant had been called calamite because its ribbed appearance
suggested a comparison with certain reeds. Since the microscope
had been used it had been found that the calamite was a near
relation to the common horse-tail. This calamite he described as
gigantic because it occasionally reached a height of 100 feet,
which was very much higher than any of the living equisetums,
which were never more than 5 or 6 feet in height. It was an
extremely interesting fact that the forests of this period were
composed of trees of quite a different order to those we had now ;
the flowering plants, and oaks, elms, etc., had not at that time
come into existence. Not only had it been possible to study the
minute structure of the stems and roots of the calamite, but its
fructification had been made out in great detail.
Comparison of Extinct and Living Species.
Those who are at all familiar with the living equisetums would
know that they had spores of only one kind, but the old calamite
had in some cases spores of two kinds, which was of some interest
botanically. In comparing the extinct calamite with the living
horse-tail it was interesting to note that the former differed enor¬
mously in size and strength from the latter. But in spite of these
differences the resemblance between the two was exceedingly
striking, so that one must bear in mind in thinking about many of
these plants that they, though in themselves quite insignificant
and apparently uninteresting, had a much more interesting history
than our oaks and other trees. There was next exhibited on the
screen a picture of some stumps of trees with their roots attached,
which were found in the neighbourhood of Glasgow some few
years ago. There some of the rocks belonged to the carboniferous
period, and these fossil stumps of trees were found in digging in
the Victoria Park. The diameter of one was about 2 feet, and
they were stumps of trees known as the Lepidodendron, a distinct
tree from the calamite. It was closely allied to such plants as our
club mosses. The next slide represented a thin section magnified
of a small twig of one of the Lepidodendron trees. In the centre the
pith consisted of a number of comparatively small and delicate
cells, surrounding which was a compressed band of wood. It was
interesting to notice that the section happened to cut through a
piece of the petrified twig at a point where the mass of wood had
given off a piece to supply a lateral branch. It was possible to
study almost in as much detail and thoroughness the structure of
the extinct plant as it was in the case of the living plant.
There was next shown an illustration of a fungus which was
found in the tissues of the Lepidodendron. Many were familiar
with the fact that our larger forest trees were attacked by various
kinds of parasitical fungi, which ate into their substance and drew
their supplies of food from the source which was prepared by the
tree for its own use. So in the fossil trees there were distinct
traces of parasitical fungi. In connection with this fact it should
be mentioned that about ten years ago a distinguished professor of
botany in Paris pointed out that from an examination of some
sections of petrified plants belonging to the coal period, he had
found distinct traces of the ravages of bacteria.
Petrified Bacteria.
A few years ago another French botanist found what he
said were the petrified bacteria themselves. The bacteria
Feb. 13, 18S7]
PHARMACEUTICAL JOURNAL.
129
which were originally there had decayed, but the spaces
left by them had been filled in by silica, preserving their
form intact. Many people were sceptical as to the accuracy
of the statement that it was possible to find traces of fossil bacteria,
but it seemed quite probable that they really had been found.
The result of an examination the lecturer had made a few
years ago showed that the resemblance of these fossil bacteria to
the modern bacteria was very striking. Just as he had pointed
out in the case of calamite that the equisetum was the nearest
living representative, so in the case of the larger Lepidodendron
they had the club moss as probably the nearest living repre¬
sentative. The next illustration was that of an attempt to restore
in the form of a picture a part of a forest of the coal period.
In detail, of course, the restoration was inaccurate,
but on the whole, so far as one could tell, it was fairly so.
One striking feature about a forest of this period was
the absence of anything like bright flowers ; there were no flower¬
ing plants in existence. The most highly organised plants which
existed then were plants closely allied to our cone-bearing trees.
Passing on from the carboniferous period to some of the more
recent periods, he next called attention to the Triassic period, to
which the red rocks of Cheshire belonged. It was from these rocks
that the supply of rock-salt was obtained. On examining the flora
of this period, and comparing them with the flora of the preceding
carboniferous period, important differences were found. In the
first place, some of the more striking plants of the coal period had
disappeared ; calamite had gone, and Lepidodendron had ceased to
exist, but the calamite was replaced at this time by a plant still
more like the living horse-tail than was the plant of the coal field.
Another difference was the much greater abundance in this
particular period of sago palms or Cycads, which were comparatively
rare now. As fossils one found them very widely distributed, and
they formed a conspicuous feature of the Triassic period.
Fossil Cycads.
The next speciman shown on the screen was that of a Cycad
found two years ago in one of the quarries of Portland. The
rocks on which Portland stood belonged to the J urassic period,
which was a good deal later than the Triassic period, and of
course still more recent than the Carboniferous period. The
rocks which formed some of the cliffs of Whitby and Scar¬
borough also belonged to this period. The term Jurassic was
derived from the occurrence of this rock in the Jura. In
these rocks a large number of fossil plants belonging to the
Cycads were found. The lecturer then proceeded to minutely
compare the fossil Cycads with specimens of the living
plants at the Kew Gardens. In dealing with fossils, one often
found a well-preserved stem without any trace of leaves attached
to it ; the leaves were found in the surrounding rock, but it was
found impossible, except in certain cases, to correlate the leaves
with the stem, and it was difficult to piece together the fragments
and to know which formed parts of the same plant. These fossil
Cycads were strong evidence in favour of supposing that at one
time the climate of this part of the world was more tropical
than it is at present. Just before the period at which chalk
was formed they found plants belonging to what was known
generally as the Wealden period. A diagram w'as then
exhibited showing the extent of the rocks of the Wealden
period, from which it appeared that over what was now the south
of England and north of France there was a large lake extending
into Belgium and Germany. Rivers carried into that lake masses
of mud and sand and pieces of all kinds of plants which had
fallen into the river. By examining these Wealden rocks one was
able to some extent to re-construct the vegetation which existed
at that time, though it was often very difficult to piece the different
fragments together. In putting together in this way the different
fragments of vegetation that were found, one was able to restore
to some extent the general character of the flora of this particular
>eriod. One particular fact about this flora was the absence of the
ligher types of plants, such as the oak, elm, birch, and so forth ; but,
on the other hand, this period was of particular interest, because there
was reason to believe that it was about this time that the highest
class of plants came into existence, and that they were developed
in some way from pre-existing plants. When they reached the
rocks about the age of the chalk, they found for the first time in
the history of the earth fragments of leaves similar to those belong¬
ing to the highest class of plants.
Flowers Preserved in Amber,
Some diagrams were next shown of examples of well-preserved
flowers which were found preserved in amber. These pieces of
amber were found in most abundance in the north of Germany, and
were simply so much resin which had exuded in a soft state from
wounded and cut surfaces of cone-bearing trees which existed
over a large part of northern Europe in the so-called Tertiary
period. This amber was another means by which plants
had been preserved as fossils. Everyone was familiar with the
case of insects in amber, but perhaps few were so familiar with
the occurrence of fragments of flowers so preserved. They next
came to the superficial strata of gravel, sand and clay, which
formed a covering over a large part of the north and middle of
England and the north of Europe generally. These rocks were
formed during the so-called Glacial period, when there was reason
to believe that ice existed over a large part of the north of
Europe. Just before that ice age began plants agreeing very
closely indeed with arctic plants extended clown to the middle of
England, and some of them had left their traces in the sand and
gravel which were formed at the beginning of the Glacial period.
An examination of these fossils enabled some light to be thrown
on the development of plant families, but it also threw a very in¬
teresting light on the conditions of climate which obtained during
the past periods of the earth’s history.
He would not conclude without mentioning by far the most im¬
portant but interesting facts which had been discovered in recent
times by a minute study of petrified fossil plants. The calamite
and the Lepidodendron were in many respects closely allied with
their living representatives, but from rocks of the same age, as
well as from rocks of a different age, petrified plants had been
found whose structure was such as to show that they combined in
themselves characteristics which one now found in distinct and
separate groups of plants. These distinct plants, which were often
spoken of as synthetic plants, were of interest, because they
showed the way to unravelling the most fascinating problems of
plant development. It was from these extinct plants of the coal
period that they had learnt recently so much as to the lines along
which plant devolution or plant development seemed to have
worked during past ages.
List of Lantern Slides
The following is a list of the lantern slides used by Mr. Seward
to illustrate his lecture : —
1. Sediment deposited on the floor of a lake.
2. Canons of Colorado.
3. Tropical forest and stream of water.
4. Illustration of the folding and contacting of strata,
5. Incrusting spring at Knaresborough.
6. Impressions of leaves in calcareous rock.
7. Cast in sandstone of large root from the coal-measures.
S. Map showing the distribution of coal-fields in Britain.
9. Spores in coal.
10. Spores in coal seen in section.
11. Cast of a calamite.
12. Section of a twig of a calamite.
13. The fruits of a calamite.
14
X^* »J > J >J i)
15. Equisetum plant.
1(3. Fossil tree stumps and roots (Lepidodendron) in rocks in Victoria Talk
Glasgow.
17. Lepidodendron twig, showing minute internal 'structure.
18. Fossil fungus.
19. Lycopodium.
20. Restoration of vegetation of coal forests.
21. Restoration of triassic vegetation.
22. Fossil cycad stem from Portland.
23. Sections showing structure of the fossil cycad.
24. Living cycads in the tropical house, Kew.
25. Illustrations of Wealden fossil plants.
26. Plants in amber.
27. Fossil arctic plants in England.
Vote of Thanks.
The President said the frequent and hearty applause during the
lecture, and at its close, showed how much it had been appreciated
by the audience. It had been a most interesting and instructive
lecture, and he was sure the thanks of all present would be most
heartily accorded to Mr. Seward. It was always satisfactory to
hear some one speaking who was thoroughly interested in his
subject, as they were all convinced Mr. Seward was, by the way he
attacked his diagrams and brought out their special points.
The vote of thanks was passed with acclamation.
Mr. Seward, in returning thanks, said he felt that his subject
was a very dull one, but, as lie had said at the commencement, it
was one in which he was deeply interested. He also wished to
return thanks to the operator, who had so skilfully thrown the
pictures on the screen.
130
PHARMACEUTICAL JOURNAL.
[Feb 13> 18ii7.
THE STUDEHTS’ PAGE.
ON DISPENSING EMULSIONS.
The pharmaceutical student and young dispenser often appears
to regard an emulsion as one of the most difficult preparations
that he can be required to produce ; the very name is a bugbear to
him. And yet with a little care and a little practice emulsions really
present in the great majority of instances no serious difficulty. No
amount of reading or verbal instruction can teach that which he
may learn by a little practice and a few failures.
An emulsion is an intimate mixture of water with a solid or
liquid with which it is immiscible, such intimate mixture being
effected by the agency of a third substance. A perfect emulsion
should possess the following qualities : — It should not exhibit the
substance emulsified in particles large enough to be distinguish¬
able by the naked eye ; it should be capable of being diluted with
water without the separation of such particles, the substance
emulsified being uniformly diffused through the water ; if, on
standing, a creamy layer should separate, this should be easily
diffused through the liquid on shaking. All these properties are
possessed by milk, which may be cited as an example of a typical
emulsion, butter-fat being in this case uniformly diffused through
an aqueous medium by means of a third substance, viz. , casein.
Milk exhibits no particles of butter-fat visible to the naked eye ; it
will bear dilution with water without such separation taking place,
and although on standing, a cream will separate, that cream can
be diffused through the liquid by shaking. And as milk exhibits,
when examined under the microscope, minute globules of fat
diffused through an aqueous liquid, so a perfect emulsion should
exhibit globules of about the same size diffused through the aqueous
liquid.
Gum acacia is to be regarded as the emulsifier par excellence, and
the student should make himself familiar with its use. He must
remember that as a general rule an oil requires one-fourth its
weight of acacia for emulsification. Let him try his hand first
of all with simple emulsions of fixed oils, such as almond or
olive, and when he is convinced of his ability to make these
without risk of failure, he may attack others that require a little
more care.
Emulsions of fixed oils with acacia can be made in two ways,
viz. , either by mixing the dry powdered acacia with the oil and
adding at once a definite quantity of water, or by making a
mucilage with the gum and adding the oil gradually. The former
method is the better and should be practised first. For this
purpose the acacia should be in very fine powder ; for making fresh
mucilage it is preferable to use it in coarse powder, in which form
it is supplied by some of the wholesale druggists. Remembering
that a fixed oil requires a fourth of its weight of powdered
acacia, let the student measure half an ounce of almond oil into
a dry mortar (taking care that the mortar is quite dry), and add to
it one drachm of powdered gum acacia. Mix these by a little
trituration and add at once two drachms of water. Continue the
trituration now rapidly and lightly until a thick white or nearly
white cream is produced and no oil globules are visible ; this part
of the operation is complete in about a minute ; the emulsion of
the oil has been effected and requires now only to be dilutee^ with
Avater added in successive portions, small at first, larger afterwards,
to the required volume. Carefully adhere to the proportions of
oil, water, and gum stated ; they are necessary to ensure success.
Do not unnecessarily triturate after emulsification has been
effected ; it can do no good and may do harm. Be very careful
that both pestle and mortar are quite dry ; otherwise the powdered
gum will form hard lumps with any moisture present. Judge of
the emulsification of the oil by the creaminess of the product and
the manner in which it adheres to the pestle.
Practise next the second method of producing an emulsion of a
fixed oil with acacia by making a mucilage with coarsely powdered
acacia and water, and adding the oil to it. Proceed as follows : — -
Weigh one drachm of powdered acacia into a dry mortar, add two
drachms of water, and make into a smooth mucilage by trituration.
It is preferable to make the mucilage fresh, as when just prepared
it emulsifies better than after it has been kept some time. Add
to this mucilage a few drops only of the oil ; triturate until
the oil is emulsified but not longer ; then add a few more
drops and triturate again. The oil should then be added in
successive portions of about twenty to thirty minims, and each
portion should be emulsified before another is added. . When
the mixture becomes thick, as it will after the addition of about
two drachms of oil, it should be thinned by a few drops of water and
the addition of oil proceeded with. After three drachms of oil have
been added, a further addition of Avater will probably be necessary.
Take care not to let the emulsion become pasty ; it should be a
uniform smooth cream. If properly made it may be diluted Avith
water added in portions to form a milky fluid. From this milky
fluid a cream w'ill rise on standing as cream separates from milk,
but this cream may easily be diffused through the liquid by agita¬
tion. This simple emulsification of fixed oil with acacia by these
tAvo methods should be practised before proceeding to emulsions
that are not quite so easy.
NOTES ON THE B.P.
Antimonii Oxidum.— When the oxychloride, formed by pouring
the acid chloride solution into water, is boiled with sodium carbo
nate, carbon dioxide is evolved and antimonous oxide obtained,
the antimonous carbonate being unstable. This is in accordance
Avith the weakly basic character of antimony. Compare antimony
with arsenic (which is even a Aveaker base) and bismuth. This
official oxide is the antimono«,s oxide, Sb203. Antimony forms, like
arsenic, two series of salts. Antimom'c oxide, Sb205, may be present
in the official oxide if the latter be overheated in drying. Its
presence is detected by its insolubility Avhen boiled with water
and excess of cream of tartar with Avhich antimonous oxide com¬
bines to form soluble tartar emetic.
Antimonimn Nigrum Purificatum. — The solubility of arsenic
sulphide in ammonia, which offers a means of purifying black
antimony, is sometimes made use of in analysis for the separa¬
tion of the two sulphides. Compare the solubility of the two
sulphides in hydrochloric acid.
Antimonium Sidphuratum. — The production of this depends
upon the capacity of antimony oxides and sulphides to unite
with alkaline oxides and sulphides to form soluble salts,
the antimonites and antimonates and thio-antimonates, etc.
The acids corresponding to these salts, which would be
formed by adding HC1 or H2S04 to their solutions, are
unstable and decompose — the oxygen acid into Avater and anti¬
mony oxide and the sulphur acid into hydrogen sulphide and
antimony sulphide. The free sulphur causes the production of
antimom'c sulphide from the antimonous' sulphide (black anti¬
mony) employed. Arsenic and tin form similar soluble double
compounds, and this property is utilised in analysis to separate the
sulphides of As, Sb, and Sn from the other sulphides (Hg, Pb,
etc.) precipitated by H.2S from acid solutions, which do not form
similar compounds, and are not, therefore, soluble in ammonium
sulphydrate.
Antimonium Tartar alum. — The aqueous solution gives a pre¬
cipitate of oxychloride with HC1. The quantitative test for
purity — weighing the Sb.2S3 precipitated by H3S — is not so easily
carried out as the Amlumetric test with iodine solution, which is
based upon the conversion of antimonows salt to antimom'c salt.
Aqua.— With the exception of chloroform and cherry-laurel
waters, the Aqute of the Pharmacopoeia may be regarded as
innocuous aromatic vehicles for the administration of more potent
remedies. It is not necessary to remember the proportion of
aromatic drug employed, but every student should prepare a small
quantity, say of aqua cinnamomi, for himself and compare his
distillate with a product obtained by agitating water with the
essential oil of the same drug. The latter method yields a prepara¬
tion inferior in aroma to the water prepared by distillation. The
waters calling for special mention are : —
Aqua Ghloroformi, a solution of one part, by volume, of chloro¬
form in two hundred of distilled water. This is a useful vehicle
partly on account of its SAveet taste and carminative action, but
more especially because of the antiseptic properties of chloroform.
A mixture containing, e.g., ext. ergot, liq. Jfi. in each dose will
keep quite good with chloroform water as the vehicle, but rapidly
becomes mouldy in a feAv days if made up with plain water.
Argentum Purificatum. — Lead and copper are the usual impuri¬
ties. Solution in nitric acid yields nitrate of silver. Excess of
ammonia added to this solution should yield a clear colourless
fluid, the soluble ammonio-nitrate (metallo-amine) of silver being
formed. A colour Avould indicate copper, which also forms a soluble
double compound Avith ammonia, having a deep blue colour. Any
lead present woiild be indicated by a turbidity due to precipitation
of lead hydrate.
pEB 13, 189?]
PHARMACEUTICAL JOURNAL.
131
Pharmaceutical Journal.
A Weekly Record of Pharmacy and Allied Sciences.
ESTABLISHED 1841.
Circulating in the United Kingdom, France, Germany,
Austria, Italy, Russia, Switzerland, Canada, the
United States, South America, India,
Australasia, South Africa, etc.
Editorial Office: 17, BLOOMSBURY SQUARE, W.C.
Publishing and Advertising Office : 5, SEQLE STREET, W.C.
LONDON : SATURDAY, FEBRUARY 13, 1897.
ARMY COMPOUNDERS AS PUBLIC DISPENSERS.
About two years ago we had occasion to direct attention
to the unsatisfactory nature of a change in the Local
Government Board regulations respecting the qualifications
of dispensers in certain unions and parishes, by which per¬
mission was given for compounders, duly qualified in accord¬
ance with the Regulations of the Army Medical Staff Corp-,
to he employed in the more public capacity. The effect of
that change was to put army compounders on an equal footing
for this purpose with Licentiates or qualified Assistants of
the Society of Apothecaries, or persons registered under the
Pharmacy Acts, and considering the exceedingly limited
amount of knowledge required on the part of army com¬
pounders, this appeared to us manifestly unfair and, from a
public point of view, decidedly impolitic. The slight
nature of the requirements in the case of army
compounders may he judged from the fact that
qualification to compound medicines may be obtained, in
accordance with the Regulations of the Army Medical Staff
Corps, by non-commissioned officers and privates who have
had six months’ training and instruction in the surgery of a
military hospital. The instruction given covers a knowledge
of (a) Latin names and words, and the symbols used in pre¬
scriptions and on the printed labels used in a dispensary ; (b)
the appearance, taste, odour, and dose of the B.P. drugs ; (o)
the official preparations of those drugs, their composition and
dose, and the quantities of their ingredients ; \d) poisons,
their names, characters, and dangerous doses, and antidotes or
other remedial measures to be adopted in cases of poisoning ;
(e) reading and making up prescriptions, labelling, and
the mode of administration of the remedies ordered ;
(/) the names and proper care of surgical instruments
and other appliances ; (g) the preparation of returns, requisi¬
tions, and other documents of like character.
The six months’ course of training is supplemented by an
examination, concerning which we could obtain no particulars
at the time referred to, but at last, by the courtesy of
Surgeon-Major Bedford, we have been enabled to find the
desired information in the Standing Orders for the Army
Medical Staff. The examination regulations as there stated
arc simple in the extreme, indeed almost archaic in their
simplicity, and even though the test is preceded by a com¬
pulsory curriculum, it is difficult to express any degree
of satisfaction with the regulations from the point of
view of the qualification of public dispensers. Briefly,
the officer commanding the Medical Staff Corps in a
district is directed to arrange for the examination of
eligible candidates for the appointment of compjunder
of medicines by a board of medical officers, and to
instruct the examiners to submit to the candidates “four”
comprehensive questions under each of the seven heads
specified above as constituting part of the course of instruc¬
tion. The questions — twenty-eight in all, he it remembered —
are to be so framed as to “ thoroughly test the candidate’s
knowledge of the uses and doses of medicine, and the
composition and modes of preparation of the principal
formulas of the British Pharmacopoeia.” In addition, his
acquaintance with the peculiarities and best modes of pre¬
serving the various drugs are to be practically tested ; as
well as his thorough knowledge of the appearance and
doses of poisons, their actions and antidotes ; his aptitude in
pharmacy and compounding, and his knowledge of the
names, uses, care, etc., of surgical instrument s and appliances.
It is not quite clear from the Regulations whether the
twenty-eight questions cover the whole of the ground specified,
but whether that be the case or not, matters wear an equally
unsatisfactory aspect. Even assuming that the brief course
of training is sufficient for turning out expert compounders
and dispensers (which we doubt), and that the examination,
if conducted by competent practical pharmacists, is a fair
test of a man’s capacity as a compounder and dispenser,
what is to be said of the appointment of a board of
medical officers to conduct such an examination 1 How are
men without any practical knowledge of a subject properly
to examine others in that subject! And that this re¬
presents the position of the average medical man with regard
to pharmacy is undeniable at a time when medical students
find less and less time to devote to the study of drugs and
their preparation in suitable forms for administration,
whilst it seems most improbable that a board of army
medical officers should consist of experts in pharmacy.
Of course, those in authority doubtless regard such
make-shift compounders as sufficiently qualified to dispense
medicines for soldiers, though it might seem that there is
little reason for discrimination in this direction in the case
of the defenders of our Empire. The War Office does as it
likes in this matter, but it is our business to protest
strongly, in the public interest, against the employ¬
ment of men with miserably inadequate qualifications
in public dispensaries. Such individuals compete on
unequal terms with properly qualified and more suitable
men, and there seems to be no sufficient reason why
even paupers should be experimented upon by amateur dis¬
pensers, masquerading as professionals. Public money should
be spent exclusively in the public interest and, it may
be suggested, such procedure as objection is taken to here
is not always consonant with the provision of snug
berths for retired soldiers. Moreover, it is rather late in
the day to assume that the united wisdom of pharmacists,
medical men, and legislators has been in the past,
and is yet, at fault in requiring, for the public safety,
that distributors of medicine should know something
more than the merely mechanical details of their craft.
132
PHARMACEUTICAL JOURNAL.
[Feb. 13, 1897
ANNOTATIONS.
The Evening Meeting (see p. 127) was well attended, despite the
somewhat unpromising nature of the topic selected by Mr. Seward
for his lecture, and those present were fully rewarded for their
attendance by the excellent entertainment provided. After all,
the lecturer always counts for much more than his subject, and in
the present instance what might have been an intolerably dull dis¬
quisition was in reality a bright and attractive address. The illus¬
trations, too, of which there was a goodly number, were excellent,
and added much to the success of the meeting. So far, Mr. Hills
has been very fortunate in the subjects explained and discussed at
meetings of the Society during his Presidency, and the latest
addition to the series, for the organisation of which he is mainly
responsible, was in no wise inferior to its predecessors.
A Case under the Medicine Stamp Duty Acts, reported on
p. 136, is of considerable importance to chemists and druggists,
as illustrating once more the enormous extent of the powers
conferred on the responsible authorities by the Acts. It has been
repeatedly pointed out and cannot be too clearly understood that
in many cases where exemption of medicinal preparations from
stamp duty is enjoyed, this exemption must be regarded by retailers
as a concession and not as a legal right. The only exemptions
under the Acts are the following (vide Calendar of the Pharmaceutical
Society, p. 168) : —
All Medicilial Drugs Whatsoever which shall be uttered or vended entire, with¬
out any Mixture or Composition with any other Drug or Ingredient whatso¬
ever. Ginger and Peppermint Lozenges or any other Article of Confectionery
unless the Person vending the same shall vend the same as Medicines or as
beneficial for the Prevention, Cure, or Belief of any Distemper, Malady,
Ailment, or Disorder incident to or in anywise affecting the Human Body
All artificial Mineral Waters, and all Waters impregnated with Soda or
Mineral Alkali, or With Carbonic Acid Gas, and all Compositions in a liquid
or solid State to be used for the Purpose of compounding or making any o
the said Waters.
Cough mixtures, fever mixtures, and bronchitis mixtures, so
labelled, are therefore as fully liable to payment of stamp duty— if
the Inland Revenue authorities choose to enforce the Acts to the
full extent — as medicines labelled with definite recommendations
for the relief or cure of disease. But by the courtesy of the
authorities, whose conciliatory attitude has been most marked, and
their desire not to interfere unduly with trade, it has been
customary to permit a certain laxity in the matter. It must be
remembered, however, that the right remains at any time to with¬
draw any concessions that have been granted, and in the case now
under notice it appears to have been felt that the privilege of sell¬
ing certain preparations unstamped had been somewhat abused.
There is no doubt whatever that the Inland Revenue authorities
were quite within their rights in pressing the matter, and this case
should serve as a useful illustration of the desirability of making
the best of the facilities offered by these authorities without
exceeding reasonable limits.
The Calendar op the Pharmaceutical Society op Ireland
for 1897 is issued in the now familiar style, and shows that the
total strength of the Society in December, 1896, was 1483, including
527 pharmaceutical chemists, 169 members, 305 chemists and
druggists, 406 registered druggists, 62 associate druggists, and 14
assistants to pharmaceutical chemists. The total number con¬
nected with the Society in December, 1895, was 1451, an increase
of 32 having thus taken place during the past year. The increase
was in the classes of pharmaceutical chemists (26), and registered
druggists (27), a slight falling off being indicated in each of the
other classes. The financial statement for the year ending
September 30 shows a balance due by the Bank of Ireland of
£78 10*\ od. , as against £170 1.3-v. 6 d. due at the beginning of the
year. The accounts of the Pharmaceutical School of Chemistry,
connected with the Society, show a balance of £2 16#. 3d., and
those of the associated Pharmaceutical School of Botany and
Materia Medica a balance of £21 5*-. 1 1 d.
The Process op Colour Photography, briefly described in last
week’s Journal, is described by Captain Abney, who witnessed the
experiments referred to, as a very remarkable one. Writing to
Nature , he observes that he went as a sceptic and, after reading
what he says, one inclines to the belief that the late president of
the Royal Photographic Society is somewhat of a sceptic yet.
According to his account a specially prepared gelatin plate is ex¬
posed, and the negative developed and fixed in the ordinary way.
A positive on a similar plate, or a silver print on specially pre¬
pared albuminised paper is next taken from this negative, and
brushed copiously over wi th a colourless liquid, probably a
mordanting solution containing albumin and salt. The blue,
grass-green, and crimson-red dyes — all in solution and mixed
writh some other ingredient besides water — are then applied in
turn. This colouring, it is stated, must be done in daylight.
The finished positive or print presents a picture in colours, un¬
derlying which is the dark brown silver image.
Why the Image Takes up the Colours Selectively is more
than Captain Abney can understand. The success of the process,
he says, does not depend upon the inventor’s manipulation, as
negatives were taken by Sir H. T. Wood, quite independently of
him, though on prepared plates. Still, the expert witness of all
this expresses himself as somewhat sceptical, and says he will not
be satisfied till he gets some plates that have been promised him
by the inventor, and taken negatives of certain test objects which
will be unknown to M. Chassagne. “If he can reproduce their
colours it will have to be without any reference to the amounts of
silver which ordinarily indicate the colour in the original, for in
the negatives sent every colour will be represented by approxi¬
mately an equal density.” At the same time Captain Abney freely
acknowledges that if the process is. thoroughly genuine, it must be
a great success, and it will have to be investigated in a
properly scientific manner. Publication of the details now secret
is promised as soon as a patent is applied for.
The Study op Experimental Teratology has been carried on
for so me time past in Paris by M. Darreste, and the Medical Pres
states that he has succeeded in establishing some curious facts in
this interesting but somewhat obscure subject. Among other
things, he has been able to show that almost any abnormal con¬
ditions acting on eggs in the early days of development can
lead to the production of malformations, a large number of such
having been produced by shaking the eggs in a machine specially
devised by M. Darreste. In the case of mammals the effect of
injuring the embryo in situ is most commonly to cause abnormali¬
ties of the amnion, a condition which leads secondarily to the
formation of various malformations. Referring to the important
part which abnormalities of the amnion play in the production of
malformations in mammalia, Dr. Councilman asserts that there is
no scientific foundation for the belief, and no proof, that maternal
impressions can have any effect on the developing embryo. All
malformations seen in man are, he contends, met with in the lower
mammalia, in whom the influence of impressions cannot be sup¬
posed to have much, if any, influence.
Feb. 13, 1897]
PHARMACEUTICAL JOURNAL.
133
The School of Pharmacy Students’ Dinner will bake place, as
already announced, on Friday, February 26, at the Holborn
Restaurant, but in place of the Duke’s Salon, it has been found
necessary to engage the Queen’s Hall, which has greater seating
accommodation. The chair will be taken by the Dean, Professor
Greenish, and a large attendance is expected, and we under¬
stand that a capital programme has been drawn up among the
students. Tickets, price 5 s., may still be obtained of the Honorary
Secretary, Mr. T. P. Tebbutt, 17, Bloomsbury Square, W.C.
The British Association Meeting will be held at Toronto during
August next, and already the local arrangements are gradually
taking shape. The Governments of Canada and of Ontario, to¬
gether with the Toronto City Council, have promised sums which
will, it is believed, fully suffice for all expenses. Con¬
cessions will be granted by various steamship companies
to members of the Association attending the meeting,
and it is anticipated that the numbers attending will be largely in
excess of any meeting held in Great Britain. Excursions will be
arranged to various parts of Canada, and many prominent
scientific men are expected to attend from the United States, whilst
the American Association for the Advancement of Science is to
meet at Detroit, at such a time that the members may
visit their British co-workers at Toronto, and invitations to attend
have been accepted by the Society of American Naturalists, and
the American Psychological Association. A writer in Nature says
it is confidently believed that the Toronto meeting will have very
largely an international character, and Canadians are reported to
be prepared to leave nothing undone which will make the meeting
a success from every point of view.
Duelling! in German Universities is described in the current
number of the Strand Magazine by an English student, whose
connection with British pharmacy is, we understand, far from
remote, and those interested in the study of relics of barbarism
will find much to interest them in this record of the crude manner
in which “honour” can be satisfied in the Fatherland. Scars on
the face are frequent results of duels, and so deeply grounded is
this insensate custom of duelling that encounters with the sword are
systematically provided for, and German students are said to hasten
and welcome the moment when they can receive a scar. The ex¬
cellent photographs illustrating the article have been taken at
Marburg, and presumably, therefore, the university of that town
has been the scene of many of the incidents referred to.
The Chemists’ Assistants’ Association Annual Dinner will
be held in the King’s Hall, Holborn Restaurant, London, on
Thursday, March 4, at 8 p.m. The President, Mr. Charles Morley,
will take the chair, and expects to be supported by Mr. Walter
Hills, President of the Pharmaceutical Society, Mr. John Harrison,
Vice-President of the Society, Dr. Symes, President of the British
Pharmaceutical Conference, Sir William Broadbent, Dr. Mac-
naughton Jones, and other prominent pharmacists and medical
men. Tickets (5s. each) may be obtained of the Council and
Stewards, or of Mr. A. Ralph Melhuish, 116, St. John’s Street,
E.C. The list of Stewards is a very representative one, and the
dinner ought to be a great success.
Coca Wine and its Dangers served the British Medical Journal
as a text last week, but it is difficult to see where the claim of that
paper for further restriction to be placed on the sale of such
wine comes in. The first argument employed is that “coca wine
and other medicated wines are largely sold to people who are con¬
sidered, and consider themselves, total abstainers.” But the term
“ wine”hasa wdl-deii nod in caning, and there is no deception practised
in thematter , soif abstainers choose to take stimulants and prefer them
in a comparatively disagreeable form, why should other people bo
restricted in their use of medicated wines? Then it is stated, appa¬
rently as a grievance, that ‘ ‘ originally coca wine was made from coca
leaves, but it is now commonly a solution of thealkaloid ina sweetand
usually strongly alcoholic wine,” and “not long ago a physician
reported that he had experienced considerable inconvenience from
taking a glass of standardised (sic.) coca wine which he had mis¬
taken for an innocuous beverage.” Apparently this medical writer
assumes that coca wine made from the leaves contains no alcohol,
and that the leaves contain no cocaine. This, at least, is the
logical deduction from his arguments. As a matter of fact coca
wine is now prepared by both methods, wine containing alcohol
being used in every case, and no attempt being made to disguise
the fact. Anyone, therefore, who resorts to the use of such pre¬
parations does so with his eyes open so far as the presence of
alcohol is concerned. The real danger is in the continued use of
cocaine, and the possibility of risk in this direction is intensified
by the varying strengths of the coca wines on the market, some
containing as much as half a grain to the ounce, and others
as little as one-hundredth of a grain. A preparation of this nature
being in active demand, the obvious remedy for the existing state
of affairs might be to make coca wine official in the next British
Pharmacopoeia. But, so far as the presence of alcohol is concerned,
total abstainers must not expect to enjoy the exhilarating
effects of wine without also experiencing a fall from grace.
A National Physical Laboratory is suggested by a correspon¬
dent of the Birmingham Daily Post to be a probable outcome of the
report presented to the British Association at Liverpool on this sub¬
ject, as Lord Salisbury is said to have consented to receive a deputa¬
tion of eminent men of science to discuss the question, on Tuesday
next, when the desirability of a considerable extension of Kew
Observatory, at Richmond, will be urged. The work of the
laboratory would comprise the comparison of standards of length,
weight, gravity, etc., commercial testing, and other physical
researches, most of which is at present carried on only at the
Berlin Reichsanstalt.
The Chemical Inactivity of the Rontgen Rays was the
subject of a paper by Messrs. Dixon and Baker, published some
time ago (see Ph. J., Oct. 3, 1896, p. 290). The results then
obtained were entirely negative, and an account of an attempt to
detect some action of the rays on chemical processes, by A. de
Hemptinne, published in the December number of the Zeitschrift
fur physikalische Chemie, and summarised in Nature, confirms
those results. No effect could be detected in the case of experi¬
ments on the conductivity of electrolytes in aqueous solution, the
hydrolysis of ethereal salts by acids, and the combination of
chlorine with hydrogen and carbon monoxide ; whilst solutions of
silver nitrate in alcohol, and of mercuric chloride and ammonium
oxalate in water, which are decomposed by light, gave only minute
and uncertain traces of change when exposed to the Rontgen rays.
The Proprietary Articles Trade Association will be the sub¬
ject of discussion at three meetings to be held next week : On
Tuesday, February, 16, at the Clarendon Rooms, Granby Street,
Leicester, at 8.39 p.m., Mr. T. Howard Lloyd in the chair; on
Wednesday, February 17, at the Royal Hotel, Grimsby, at 3 p.m. ;
and on Thursday, February 18, at the Imperial Hotel, Hull, at
8.30 p.m. Mr. W. S. Glyn-Jones is expected to be present at
each meeting to explain the present position of affairs,
134
PHARMACEUTICAL JOURNAL*
.Feb. 13, 1897
(MEETINGS Op SCIENTIFIC SOCIETIES
- ♦ -
Chemical Society. — Thursday, February 4, Mr. A. G.
Vernon Harcourt, F.R.S., President, in the chair. — The distin-
fuished physicist, Lord Rayleigh, at this meeting treated the
ellows of the Chemical Society and a large number of visitors to
a lecture on —
The Oxidation of Nitrogen,
which was beautifully illustrated by experiments. Long before
eight o’clock the lecture room was invaded by members for the
purpose of examining the apparatus which was arranged on the
bench all ready for action. Inquisitive minds were invited to be
careful in the neighbourhood of the apparatus by a placard bear¬
ing the words “Dangerous : do not touch,” in letters large enough
to have been read with ease from the other side of Piccadilly.
Naked wires were no doubt lurking about, and the placard thus
conspicuously displayed was evidently to prevent scenes that
might have detracted from interest of the lecture. Curiosity
having been satisfied the benches soon became filled up, and then,
after the transaction of routine business, Lord Rayleigh stepped up
to the platform, the apparatus for the absorption of gases having
meanwhile been set working. Lord Rayleigh thus commenced
his lecture, weirdly accompanied by the whir of a dynamo
and the fantastic flickering of flame in a huge glass globe,
exhibiting under the electric influence the pretty but somewhat
uncanny phenomenon of fluorescence. The lecturer at the outset
recounted an experiment performed by Davy, in which the nitro¬
gen dissolved in water on oxidation yielded nitric acid, and re¬
acted very perceptibly on litmus paper. Davy’s experiment was
performed with two cups of gold connected with the two poles of
a battery of 100 elements. After ten minutes’ working they
showed strong acid reaction, and both nitrous and nitric acid were
found. Lord Rayleigh repeated this experiment in a modified
form. Instead of two gold cups he used a block of paraffin, in
which two holes or cavities were made. The holes were kept
covered with glass shades. In this experiment, however, he
found no reaction with litmus. His next experiment was with a
large glass globe, having a capacity of five or six gallons, inverted,
and supplied with large platinum electrodes. He finds that every
increase in the size of the vessel is accompanied by an increase in
the absorption of gases, and he attributes this to the larger surface
of alkaline solution which is kept running over the internal surface
of the globe. Everything is introduced into this globe through an
india-rubber bung in the neck of the inverted globe.
There are two tubes for the current from the alterna¬
ting current dynamo, one for the fountain of alkaline
water, one for drainage, and two for the gases introduced.
This experiment was in operation all the time Lord Rayleigh was
speaking. Between the two massive platinums there was an arc
of flame from the burning gases, and against a white screen the
red fumes of nitrogen peroxide could be distinctly seen. It is
necessary that the platinums should be massive as they might
otherwise fuse, though it is essential they should be very hot. The
absorption by the alkali is very complete, but it is necessary, in
oi’der to get rid of the oxides as they are formed, that the alkali be
renewed occasionally. If the nitrogen and oxygen are in the right
proportions, the rate of the absorption of gases is about 21 litres
per hour. The only fear of the experiment going wrong is failure
of the fountain. The lecturer, looking at the apparatus, made a
mental calculation as to the electric power then at work, and put
it down at about one horse power. — Professor Armstrong was the
first to speak, and made some remarks on the conditions to which
the platinums in the globe were exposed. He also stated that Lord
Rayleigh was rapidly becoming an accomplished chemist. — Pro¬
fessor Ramsay also spoke, and the President went at some length
into the question of the absorption of the gases. — Professor
MacLeod mentioned that in an experiment by Cavendish, potas¬
sium nitrate was said to be produced. An experiment by himself,
however, showed that nitrite was decidedly present. In looking
over the list of Fellows of the Chemical Society, he thought the
present occasion appropriate to mention that Lord Rayleigh was
not yet a Fellow. — The second paper was on —
An Improved Apparatus for Steam Distillation.
BY F. E. MATTHEWS, PH.D.
He described two pieces of apparatus which were practically
automatic, one for the distillation of liquids lighter than water.
and the other for liquids heavier than water. The diagrams will
explain the action of the ingenious apparatus.
Diagram I. — A contains water and the liquid to be distilled.
The steam and volatile liquid pass into the aperture marked at C,
and both condense in D and drop into B, nearly filled with water.
Fig. 1. — For Liquids heavier than Water.
As the volatile body collects in B, the surplus water runs back
through A into A, and this goes on continuously as long as it is
necessary to keep up the distillation.
Diagram II. — A contains the liquid to be distilled. The vapour
passes through B into the condenser C, collects on the surface of
Fig. 2. — For Liquids lighter than Water
the water in G, and drives the latter back through the tube F into
A. D and E show the amount of liquid collected.
The following papers were also read : — “ Researches in the Stil-
bene Series, I.,”byJ. J. Sudborough, Rh.D. ; “Diortho Substi¬
tuted Benzoic Acids, III., Hydrolysis of Substituted Benzamides,”
by J. J. Sudborough, Ph.D. , P. G. Jackson, and L. L. Lloyd.
Lemon Juice in Ophthalmia Neonatorum. — Szawelski (Gaz.
Lekarska) endorses Penard’s statement that the instillation of a
few drops of lemon juice into the infant’s eyes immediately after
birth is an excellent means of preventing purulent ophthalmia,—
B, M. J. Epit., 2/96/72,
Feb. 13, 1897]
PHARMACEUTICAL JOURNAL.
135
THE WORLD Op PHARMACY.
- + - -
BUSINESS MEETINGS.
Liverpool Pharmaceutical Students’ Society, Thurs¬
day, February 4. — Mr. John Jones, President, in the chair.— Mr.
Morgan drew attention to a
. Prescription
lie had had to dispense containing phenol, 1 gramme ; /3-naphthol,
5 grammes ; salol, 5 grammes ; powdered rhubarb, 2 grammes.
This was to be made into powders, but they became moist when
•made with one sample of /3-naphthol, but not with another. He
wished to know the cause of the deliquescence, and why it should
mot have occurred with both samples. It might have been due,
Mr. H. Wyatt, jun., suggested, to one of the /3-naphthols contain¬
ing a-naphthol, which was more soluble and of a lower melting point
than the /S variety. —The President exhibited a dried
Coffee Plant
with fruit from Liberia, and asked if any member who had had
experience of foreign prescriptions could tell him what “tinctura
ferri pomati ” was, as he had had to supply it to a German ship’s
medicine chest. — Mr. Wyatt informed him it was made from an
extract obtained by acting on metallic iron with sour apple juice,
and was, if he remembered aright, official in the German Pharma¬
copoeia, at any rate he would find formula for it in Dorvault’s
‘L’Officine’ and in Jourdan’s ‘Pharmacopoeia Universalis.’ — A
paper on
Ferns
was then read by Miss E. M. Wood, a lady who has
frequently favoured the students with papers on botanical
subjects, and who is well known in Liverpool as an authority on
the local flora. The general characteristics according to which
ferns were classed, their method of reproduction and the chief
representatives found in Great Britain were rapidly touched upon
and illustrated by a fine collection of herbarium specimens, mostly
of Miss Wood’s own collection. Of those to be found in the
immediate neighbourhood of Liverpool, Osmunda regcdis, the king
fern ; Botrychium lunaria, moonwort ; Ophioglossum vulgatum,
adder’s tongue ; Lastrcea filix-mas, male fern ; A thyrium filix- fcemina,
lady fern; Asplenium ruta-muraria, Wallrue ; A. marinum, sea
spleenwort ; and of course Pteris aquilina, the common brake were
'described and exhibited, as was also a drawing of a fossil maiden¬
hair fern from the Teiliana Quarries, Sphenopteris teiliana, dis¬
covered by Miss Wood. At the close of an exceedingly interesting
paper, a vote of thanks was accorded Miss Wood on the motion of
Mr. Frank Walker, seconded by Mr. T. S. Wokes.
Edinburgh District Chemists’ Trade Association,
Friday, February 5.- — Mr. John Bowman, President, in the chair.
— Mr. C. A. Macpherson explained his proposal to institute
A Scheme of Exchange
among the members of the Association for out-of-the-way proprie¬
tary articles and rare drugs or chemicals. Great inconvenience
and delay was sometimes caused by a difficulty in procuring these
articles, sometimes from London or direct from the makers.
Considerable loss was also incurred by having to purchase an
original bottle or package when perhaps only a small quantity was
required for a prescription, which was only once dispensed. He
thought there must be a large stock of these articles lying practically
useless on the shelves of many pharmacies in the district, and his
proposal was that members should send a note of such articles
as they had in their possession, so that he might prepare a list that
could be issued with the monthly billets to all the members. In
■this way anyone having a prescription for any of these articles
would know where it could be procured. That would be a con¬
venience to the member who wanted the articles, and it would
also be a relief to many who would gladly get rid of superfluous
stock in this way. Of course it would have to be understood that
no member would put upon the list any article that was not in a
saleable condition, or that he would not himself be justified in
selling to the public. There might be difficulties in the details of
the plan, but he moved that it be remitted to the Committee to
carry out the scheme and institute such an exchange. The
suggestion met with the unanimous approval of the meeting, and
the motion, being seconded by Mr. Forret, was agreed to. The
Secretary, Mr. C. F. Henry, said he would willingly undertake
the work of trying to make the exchange a success.
Midland Pharmaceutical Association, Tuesday, Feb¬
ruary 2. — Mr. Gibson, President, occupied the chair. — Dr. T.
Wilson read a paper on — -
Doctors and Medicine Men.
In the course of his remarks he said that an interchange of
opinions and thoughts between the members of the medical pro¬
fession and of that Society could hardly fail to promote good
feeling and a better understanding. Chemists, like doctors,
followed a calling which partook of the nature of a profession as
well as of a trade ; in the chemist’s case no doubt the trade
element was more prominent, but it was always to the fore with
the medical man, too, enforced by that objectionable rule of
advanced civilisation which expected twenty shillings in the
pound, even by those whom it was the custom to sneer at as
scientific and learned — and therefore of bad business habits
or of no business aptitude at all. If they could confine themselves
to the professional aspect of their work, there would then only be
room for friendly rivalry and good-natured simulation in their
attempts to promote the good of mankind. Unfortunately, how¬
ever, the business element was thrust upon them all, and that it
was which brought out the lower part of their nature, and led their
two callings into occasional jealousy of each other’s proceedings.
He traced the history of the two professions, and said that the
practice of medicine might be divided thus — (1) the great mass of
general practitioners, including the physician, surgeon, ob¬
stetrician ; (2) the pharmacist ; (3) the specialist ; (4) the
large class of more or less skilled nurses ; (5) the many
kinds of base imitations, such as medical botanist, medical
galvanist, cancer curer, patent pill manufacturer or vendor,
botanic physician, and finally the peripatetic mountebank who
flaunted his quakery in the market places, sometimes with a
gilded chariot, sometimes with a worn-out tin tray, as his place
of business. All those various classes had their prototypes in very
early stages of civilisation, and their evolution could be traced
down the stream of time. He traced in an interesting manner the
development and practice of the medicinal man in several nations,
and observed that chronologically the medicine man was evolved
before the priest among various tribes. Later the medicine man and
the priest were practically the same, but with the rise and improved
culture of the priesthood came greater knowledge of medicinal
agents, which gradually ceased to be regarded as acting supernatur-
ally, and among the early Egyptians medicine was practised by an in¬
ferior order of the priests. The two classes, priest and medicine man,
both foreshadowed the physician, but the latter only to the extent
of using the same means. One of the leading theories of the
medicine man’s treatment of disease was to render the body of
his patient obnoxious in some way to the invading spirit, and as
one result of that idea the impression seemed to have arisen
that the efficacy of medicine bore a distinct relation to
its disgusting nature. That impression, too, was not confined
to the early or even mediaeval times, but was common even in this
latter end of the nineteenth century. Having dealt in detail with the
progress of medicine among the ancients, he said that in our owTn
country the growing influence of the universities had given a great
impetus to the improvement of the study and practice of medicine,
in common with other departments of knowledge. By the end
of the twelfth century the profession had been separated into
two divisions — physician and surgeon, and about the same
time some members of it began to specially devote themselves
to the composition of medicine. The chemists and druggists, as they
came to be called, were late to organise themselves, and not until
1841 did they form the Pharmaceutical Society of Great Britain. The
Society was incorporated two years later by charter, and in 1852
the Pharmacy Acts were passed to regulate the business and quali¬
fications of chemists and druggists. Since that time the calling
had enjoyed a position in some respects analagous to the profession
of medicine. If the apothecary of the time of Shakespeare could
be brought back, and could have shown to him the present-day
stocks and places of business, and have explained to him the
methods and science, he (Dr. Wilson) fancied he would think him¬
self mistaken. At any rate, if the divine William was not grossly
libellous in his description of the apothecary of his day, the condi-
136
PHARMACEUTICAL JOURNAL.
[Feb. 13, 1897
tions had so changed for the better that their imagined visitor
would hardly be able to recognise his calling. Perhaps, however, the
poet was in error after all, and was really describing the medical
botanist, or the botanic physician of those days. The history of
medicine, as of all other branches of learning, told that from an
elementary beginning, with which grains of truth were scattered
among bushels of error, knowledge gradually increased with the
ages, and successive races and generations of men were able to
separate some of the wheat from the chaff of the erudition which
was handed on to them.
Pharmaceutical Society of Ireland (Council Meeting),
Wednesday, February 3. — Mr. W. F. Wells, jun., President
in the chair.- — The report of Dr. Duffey, the Lord Lieutenant
Visitor, stated that during the year 95 candidates presented
themselves at the
Preliminary Examination,
two of whom were women, and 51 passed. The results seemed to
show that the apparent improvement in the general preliminary
education of the candidates shown in his report for last year had
not continued. As in former years the optional subject selected
by the majority of the candidates was chemistry, and next
came French ; but the majority of the candidates displayed
discreditable ignorance of that language. He suggested that
elementary chemistry should be made a compulsory subject of the
Preliminary examination. For the Licence examination sixty-
five candidates presented themselves, of whom thirty-two were
successful. The largest number of failures was in chemistry. The
report was referred to the Law Committee.
The L.G.B. and Drug Contracts.
A letter from the Local Government Board of Ireland stated that
they had the letter of the Council on the subject of the way in
which the drug contracts for Granard Poor Law Union had been
given under consideration. — The President referred to an article
in the Medical Press condemning what it described as the “ middle¬
man” arrangement, which was being adopted for the supply of
drugs to workhouses.
The Untruthful Statement in “ Truth.”
On the subject of a statement in Truth newspaper, relative to
the examinations of the Irish Pharmaceutical Society, and of
which its Council had complained, the letters of Mr. Bremridge,
Registrar of the Pharmaceutical Society of Great Britain, to Mr.
Ferrall, Registrar of the Irish Society, of December 4, 1896, and
January 2, 1897, were read. — The President said he "had hoped
that they would have got a reply stating what now appeared to be
the truth, namely, that the statement complained of was not made
in the offices of the British Society and by a responsible official,
as the editor of Truth said. The grievance the Council had to
complain of was that the Council of the Pharmaceutical Society of
Great Britain had not acknowledged that its official had made
a mistake. A proper apology should have been sent or a with¬
drawal of the statement. The British Registrar talked about
fraternal feeling, but he did not see how it could exist. They
knew now who were their friends, and that they had very little to
look for from the British Society, which allowed them to be stabbed
in the back in that manner. The editor of the Pharmaceutical
J ournal had made a pretty strong personal attack (sic ) on him
(Mr. Wells) ; but the editor of that journal was himself in a fog
about the matter. His (Mr. Wells’) only public statements were
the letter he wrote to that journal on the subject in question, and
the report of his interview with the representative of the Dublin
Evening Telegraph. What the editor attributed to him he must
have seen in another Dublin paper, but not a single word of what
the editor took exception to was uttered by him (Mr. Wells).
Miscellaneous Business.
A donation was received from the Pharmaceutical Society of
Great Britain and their Calendar for 1897, and on the motion of the
Vice-President, seconded by Mr. Grindley, thanks were voted to
the donors. The subject of giving gold and silver medals for
the best answering at the Licence Examinations of each year was
referred to a committee with a view to the carrying of the plan
into effect.
SOCIAL MEETINGS-
Brighton Junior Association of Pharmacy, Wednes¬
day, February 3. — The usual fortnightly “social and musical”
evening of the above Association took place at the headquarters of
the Association, Newburgh Hall, Cannon Place. There was a
large number of members and friends present, proving the popu¬
larity of these socials, and under the very genial chairmanship of
the President, Mr. A. T. Jeeves, a very pleasant evening was
spent by all. Mr. C. A. Blarney (the Hon. Sec.) was responsible for
the programme, the arrangements for which he carried out in his
usual very creditable manner.
Chemists’ Assistants’ Association, Thursday, February 4.
— The second “Cinderella” dance of the season was held in the
Dorset Hall Portman Rooms, Baker Street, W. When Bacon’s
quadrille band struck the chord for the first dance there was rather
a thin room, but as the evening progressed the number of dancers
increased considerably, until the hall was well filled. Dancing
was kept up with much vigour until 12 o’clock, Mr. C. W. Martin
having added much to the enjoyment of all present by the efficient
manner in which he discharged the duties of M.C.
Plymouth, Devonport, Stonehouse and District
Chemists’ Association, Wednesday, February 3. — Mr. J.
Harvey Bailey in the chair. — At the annual smoking concert in
connection with the Junior Section a large company was present,
numbering about seventy, and a capital programme was rendered.
Songs were given by Messrs. Andrews, Bogan, Doddridge, Harris,
Hill, Johnson, Crabb, Aylesward, Weeks, Webb, and Yoe (in
character), banjo solos by Mr. Reynolds, readings _ by Messrs.
Luxton (Exeter) and Bernard Mervyn. Great credit is due to the
Committee for the admirable arrangements and the successful
manner the entertainment passed off. The Committee consisted of
Messrs. H. C. Cautle, E. T. Cocks, E. Green, E. A. Hodge, W. A.
Shakerley, and J. A. Buckley, Hon. Sec. It was decided to hand
the balance over to the Seniors towards the new rooms.
LEGAL INTELLIGENCE.
PROCEEDINGS UNDER THE MEDICINE STAMP ACT.
Prosecution of a Chemist.
At the Lambeth Police Court on Monday, Mr. R. Willson, a
chemist carrying on business at 52, New Kent Road, was sum¬
moned before Mr. Hopkins, at the instance of the Board of Inland
Revenue, for having sold by retail a mixture contrary to the
Statute.
Mr. Dennis (barrister) appeared for the prosecution, and said the
revenue authorities allowed a certain amount of latitude to
chemists as to the manner in which they should be allowed to
label their compounds, but in this case they felt that the defen¬
dant had gone considerably beyond the mark, and, therefore, they
felt bound to bring these proceedings. The label used by the
defendant on the bottle produced bore the following words
“ Willson’s Cough, Fever, and Bronchitis Mixture,” and this
description, it was contended, brought him within Section 2 of the
Act of George III.
Mr. Wm. Spears, a messenger attached to Somerset House,
deposed to going to the defendant’s shop in December last, and
purchasing a bottle of the mixture which he now produced. He
thought it was the defendant who supplied him with the mixture,
but could not say for certain.
Defendant : I submit that the evidence of the witness puts an
end to the case. It has been held in an action brought by the
Pharmaceutical Society that the actual vendor was the person
liable.
In the course of some further argument, the defendant contended
that this was nothing short of a case of blackmailing on the part
of a public body, which did not know its business. They had,
he said, offered to forego these proceedings if he would pay them
a fine of one pound and say nothing about it, but he declined to
have anything to do with their suggestions of a compromise, on
the ground that if he had done anything wrong, he would stand
by it in a Court of Justice for the benefit of, and as a warning to
other chemists.
His Worship said the words of the Statute were very wide, and
Feb. 13, 1897]
PHARMACEUTICAL JOURNAL
137
the question he had to consider was as to whether or not the
defendant could get outside it. As the things stood at present it
was difficult to see how he could do so.
The defendant saidhe claimed no proprietary right over the article,
nor did he represent it as a curative agent for any particular malady,
And, therefore, it could not he suggested that it was a patent medi¬
cine within the meaning of the Act. In his opinion the Board of
Revenue was a disgrace as a public body, and was
bringing .these petty prosecutions against chemists simply
for the purpose of wasting the public funds. If he had paid the
£1 that was demanded, nothing would have been heard of this case;
but he had declined to have anything to do with the Board.
His Worship said, the whole question to be considered was as to
whether or not the defendant had rendered himself liable under the
Section of the Act by holding out to the public that his preparation
was capable of the cure or relief of disease. Upon the evidence
before him he was quite satisfied that the defendant had infringed
the Act by the use of the labels complained of, and therefore he
should impose a penalty of 40s. , together with 2s. costs.
In reply to defendant, Mr. Hopkins said he could appeal.
Parliamentary notes and news.
Corporate Benevolence- — The question of Sir John Brunner,
to which we referred last week ( ante, Sup., p. 120), no doubt raised
the hopes of his constituents in anticipation of good things. But
hope in this instance, as in most others in this world, told a
flattering tale, for Mr. Balfour has brutally dispelled the bright
visions of corporate donations of recreation grounds and scientific
institutes, by declining to take up Sir John’s proposal. The matter
would raise interesting but intricate questions, said the Leader of
the House, but he could not advise the Commons to embark upon
the discussion of such questions. The ‘ ‘ limited owners ” which
the member for Northwich had in mind, may, if they wish, overcome
the difficulty in much the same way as the directors of “ Camwal”
did when they wanted to support the Pharmaceutical Benevolent
Fund.
Opium is a kind of red rag to many worthy persons in these
islands, for they see in it the potent agent of human demoralisa¬
tion. These anti-opium crusaders were strong enough some time
ago to involve the country in an Opium Commission, with an
expenditure of several thousand pounds, and they are still actively
at work in and out of Parliament to check the traffic in narcotic
drugs. Those who sympathise with these views will, therefore, be
particularly interested to learn from Mr. Chamberlain’s reply to
Mr. H. J. Wilson (Holmfirth) that the Ceylon Government has
recently prohibited the importation of hemp drugs into Ceylon,
and has doubled the import duty on opium, which is now two
rupees per lb. The action of the Ceylon Government has the
approval of our own Colonial Secretary.
Mr. Lloyd-George (Carnarvon) will, on the Civil Service
•estimates, call attention to the congestion of work at the Local
Government Board, and he intends to move a resolution expressive
of the desirability of removing the congestion. Perhaps Mr. Lloyd-
George has overlooked or forgotten that an Inter-Departmental
Committee is now engaged in investigating the matter.
The Tuberculosis Commission has overwhelmed itself with
evidence during the last few weeks, and is constrained to suspend
its sittings for a time to allow for the digestion of the mass of
facts already accumulated. On re-assembling about the beginning
of April, it is hoped to arrange for the Scotch and Irish authorities
on agriculture to give their views on the subject. Meanwhile
some of the Commissioners will visit the continental capitals for
the purpose of inquiring into the methods there adopted for the
inspection of meat, and the precautions taken for ensuring the
purity of food and drink sources. Perhaps these are some of the
things they do so much better beyond the Channel.
The Order Paper for Wednesday, 10th, presented the curious
phenomenon of having all three Early Closing Bills tabled for
second reading. Neither succeeded in attaining the coveted
Stage, though Mr. Duncombe and Sir Charles Dilke were both in
their places expectant and in readiness.
CORRESPONDENCE.
All Articles, Letters, Notices, and Reports Intended for
publication in the Journal, Books for Review, and com¬
munications respecting Editorial matters generally,
must, be Addressed “Editor, 17, Bloomsbury Square,
London,” and not in any case to individuals supposed
to be connected with the Editorial Staff. Communica¬
tions for the Current Week’s Journal should reach the
Office not later than Wednesday, but news can be Re¬
ceived by Telegraph until 4 p.m. on Thursday.
Any Instructions from Members, Associates, and Students of the Pharmaceutical
Society, with reference to the transmission of the Journal, should be sent to
the Secretary — Mr. Richard Bremridge, — 17, Bloomsbury Square, London.
Business communications— including advertisements, orders for copies of the
Journal, and instructions from Subscribers respecting transmission of
same— must be addressed to the Publishers, 5, Serle Street, Lincoln’s Inn,
London. Cheques and money orders should be made payable to “Street
Brothers.”
Correspondents who wish notice to be taken of their communications must
write in ink, on one side of the paper onlj», and should authenticate the
matter sent with their names and addresses — of course not necessarily for
publication. No notice can be taken of anonymous communications.
Drawings for illustrations should be executed twice the desired size ; clem
sharp lines being drawn with a pen and liquid Chinese ink. Shading by
washes is inadmissible. Photographs can be utilised in certain cases.
Names and Formulae should be written with extra care, all systematic names
of plants and animals being underlined, and capital letters used to commence
generic hut not specific names.
Reprints of articles cannot be supplied unless authors communicate with
the Editor before publication.
The Benevolent Fund.
Sir, — May I be allowed (if not too late) to suggest, as it is tfie
sixtieth year of Her Majesty’s reign, that ladies be invited to
attend the Dinner in May next, as it has been suggested to ask
them to collect for the Fund. It may induce them to do so if they
know that the amount so collected will be presented by them to
the Chairman on the occasion.
Greenwich, February 8. A. J. Brown.
Divisional Secretary.
Sir, — The financial position of this Fund having been lately
prominently before the subscribers, and the difficulty of meeting
the demands upon it officially announced ; the occasion would
appear to have arisen for the Council to reconsider the step taken a
few years since, when the incomes of the annuitants were in¬
creased. It seems fairly evident that this increase was hardly
justified by the position of the Fund; nor is the condition of our
calling such that we can hope for more than a temporary augmen¬
tation of the Fund, whatever efforts are put forth. It must be
borne in mind that it is (or should be) only those whose families
are unable to support them who come upon the Fund,
to such the income formerly granted insured their being taken in
and cared for by someone ; and in the presence of the number of
candidates this is all those who administer the Fund are justified
in providing. I have sufficient faith in the generosity of the
present annuitants to believe they would prefer to enjoy a
charity shared by as many as possible of those equally necessitous
— even though their own incomes were slightly reduced. I note
at the last Council meeting that no movement was made to elect
an annuitant to fill the death vacancy then announced, although
the case of Mr. Tonkin Young, who so nearly succeeded on the
last occasion, must be sufficiently pressing.
Plymouth, February 9, 1897. R. F. Roper.
The Ginkgo Tree.
Sir, — In your “Annotations” you recently recorded the discovery
of “ spermatozoids ” in the pollen grain of the above tree. I
daresay many of your readers know that there is a very fine
specimen growing in Kew Gardens. I think it will interest vour
botanical students to enumerate some points in this tree, which for
myself have for some years been regarded as forming an epitome of
the development of our flora. It is indigenous to Japan, whilst
f eologically it may be traced almost unaltered to the coal series.
ts leaves have the furcation of the fern, one of its names
is Salisburia adiantifolia j botanically it is a coniferous tree, its
habit is that of a deciduous tree, approaching the pear, etc.
In winter, viewed in profile, the appearance of the lateral branches
138
PHARMACEUTICAL JOURNAL.
[Feb. 13, 1897
recalls both coniferous and pear trees. Personally, I have derived
much pleasure from reading your short annotation. In winter
there are several interesting characters noticeable in our forest
trees, e.g., the young beech with its upper branches reminding
us of the palm fronds ; many of the elms, again, may be seen more
or less excurrent. These all suggest transitional types of the same
species. Of course the Lombardy poplar stands as the criminal
stands to-day amongst his fellows, the survival of an atavic form.
Its rhomboid leaves approach the ginkgo more than any other
leaves I know in their venation.
Dulwich, January 30, 1897. J. Barker Smith.
Sweating the Dispenser.
Sir, — In an annotation in the Journal for January 30, page 93, a
guardian of Camberwell Parish says a dispenser could turn out
five hundred bottles a day, I suppose on the same lines as a beer
bottler sets to his work, till the barrel is empty, then commences
on another. It would be interesting to know how many dozen a
day each bottler fills at a firm like Foster’s, where there is no
danger of a mistake, the different kinds of beer being kept in
separate cellars. This is not so in a dispensary, where poisons are
on the left and right of the dispenser. Ought the state of
things spoken of be allowed in an institution where money
is no object, or at least ought not to be, if the cure of the patients
is the purpose for which it is being spent. That it exists in
an infirmary under the control of a Government department
spending thousands of pounds annually in combating with disease
is an anomaly. Visiting one of these institutions to see “ How it
was done,” I saw the dispenser with a tray full of bottles before
him for all kinds of mixtures, not all stock, as is supposed.
Being curious I waited to see how the dispensing was done ; there
was mist, potass, iodid., mist, acid c. nux vom., mist.,
acid. c. tarax., mist, quinse c. ferro, powders of antipyrin
calomel, pulv. ipecac, co., etc. To my intense surprise
there was neither scales nor measures used for any of them,
the ingredients being guessed and the bottles passed to a pauper
inmate to fill with water. Asking why this was so I was informed
that it would be impossible to get through the work in any other
way ! Passing through the other departments of the institution I
found the carpenter at work in his shop making a door ; he was
carefully using rule and square to bring his work into shape.
Further on I found the plumber repairing some utensils ; he again
was using his tools with the utmost care to make the utensils fit
into their frames. There was no hurry in either case. The
baker was also weighing his flour, yeast, etc., for the bread.
All working with ease compared with the dispenser. So I
concluded tbat food, doors, and utensils were of more importance
in their preparation than the medicines for the sick and dying
patients ! The prescriptions must be made up to-day regardless
of the number, the doors and utensils can wait till to-morrow. If
dispensers are expected to do impossibilities, what results can be
had from their work ? Are there are no chemists and druggists
with a sufficient love for their fellow-creatures willing to become
guardians of the poor and see that the sick poor get their prescrip¬
tions properly dispensed, and that their brothers in pharmacy, the
dispensers, are not sweated ?
February 2, 1897. Anti-Sweater (78/38).
Check Tills — A Want.
Sir, — Perhaps some of your numerous readers might suggest
some simple mode of converting an ordinary cash till into that of
a check one. I am sure it could be done by some easy yet
ingenious arrangement, and with little expense. The suggestion
may awaken some of the latent talent of mechanism which, I am
sure, many of our brethren possess. Failing this, some one might
give their experience of the existing check tills, stating whether
they find them thoroughly effectual, and which make they con¬
sider the best.
February 1, 1897. Inquirer (78/31).
Ancient Pharmacy.
Sir, — For the first mention of drugs one must turn to the oldest
literature of the world or such literary remains as have been
brought to light in the form of monument, clay tablet, hieroglyph,
etc. , of the earliest civilisations of which any record exists. The
Jewish scriptures, while of no mean antiquity, cannot, of course,
compare in age with the literature of earlier nations — the Egyptian,
the Chaldsean, the Assyrian, the Aryan, and others. In the
ancient records of all these races there are references to the heal¬
ing art. The Rig Veda, of India, the Ebers Papyrus, of Egypt,
and Assurbanipal’s Clay Tablets (or “ library of bricks,” as they
have been termed), at Nineveh, are some of the best known, but
hardly a year passes now without some valuable addition being
made to our knowledge of the old-world civilisations. With regard
to the drugs of the Bible, Mr. Casson’s remark that many of the
translations are misleading, doubtless holds good in respect of the
authorised version, but these defects have largely disappeared in
the revised version. To cite a single instance only : The “ cam-
hire ” of the authorised version is now correctly rendered “ henna,
owers,” Lawsonia inermis — source of the well-known oriental dye,
and a plant of much fragrance.
Among the interesting Bible drugs not mentioned by Mr.
Casson may be named the mandrake or love apple (Mandragora.
officinalis), a reputed cure for sterility, and balm of Gilead, an oleo-
resinous product of Balsamodendron opobalsamum, a veritable
panacea of the ancients. In Coverdale’s translation, 1536, known
as the Treacle Bible, “balm” was rendered “triacle,” “Is there
no triacle in Gilead, is there no physition there ” ? The apocryphal
books are, perhaps, even richer than the canonical ones in refer¬
ences to the healing art. It has been suggested that the author of
‘ Ecclesiasticus ’ must have been a physician. The book is so full
of medical allusions, a collection of them would indeed make a
very good “ Health Manual.” A few of them may be quoted : —
“ Learn before thou speak,
And have a care of thy health or ever thou be sick."
“ Better is a poor man being sound and strong of constitution
Than a rich man that is plagued in his body.”
“ Be not insatiable in any luxury,
And be not greedy on the things that thou eatest.”
“ Healthy sleep cometh of moderate eating,
He riseth early and his wits are with him."
“ The pain of wakefulness and colic
And griping, are with an insatiable, man."
“ Because of surfeiting many have perished,
But he that taketh heed shall prolong his life.”'
“ The Lord created medicines out of the earth,
And a prudent man will have no disgust at them."
“ Honour a physician according to thy need of him with the honours due
unto him."
“ The skill of the physician shall lift up his head,
And in the sight of great men he shall be admired."
“ There is a time when in his very hands, is the issue for good.”
The story of ‘ Tobit,’ another of the uncanonical books, has an
interesting reference to some cases of healing. This is not a col¬
lection of maxims like ‘ Ecclesiasticus,’ but a simple work of
Jewish fiction. It is not surprising, therefore, to find magic intro¬
duced into the narrative. The patients are a woman who was
possessed of a devil and a man who had become blind by the
formation of “ white films ” over his eyes. The remedies employed
were no less curious than the diseases, being furnished by the
internal organs of a fish. “ Touching the heart and the liver, if a
devil or an evil spirit trouble any, we must make a smoke thereof
before the man or the woman, and the party shall be no more
vexed. But as for the gall, it is good to anoint a man that hath
white films in his eyes, and he shall be healed.” And with these
primitive medicines Sarah and Tobit were duly cured of their
respective complaints.
Brighton, February 2, 1897. C. S. Ashton.
The Regulation of Prices.
Sir, — Many letters having been written on the question of
cutting prices, may I ask you, Mr. Editor, to kindly find space for
the following letter in your valuable J ournal ? I am of opinion
that it rests with the Council of the Pharmaceutical Society, and
with them alone, to stop the absurd cutting of prices, and I should
suggest the following course : — I am convinced that if the Pharma¬
ceutical Society raised the standard of the Preliminary examination
to a sufficiently high grade as would compel the future pharmacist
to have had a thorough middle-class education, and it compelled
the would-be apprentice to pass that examination prior to the
commencement of his apprenticeship, the whole matter of absurd
cutting would soon die out. I should suggest as a good standard
the equivalent of the Junior Cambridge or Oxford Local Examina¬
tions. The result of this would be a large dimiuation in the
number of pharmacists by the obtrusion of the uneducated section,
thus putting a better class of men in the business, who would
appreciate the difference between a profession or professional trade
Feb. 13, 1897]
PHARMACEUTICAL JOURNAL.
189
and ordinary trade, with the result that prices would soon go up to
a fair scale for professional work, such as dispensing, and also for
the sale of drugs. Also the educated chemist would not coun¬
tenance being employed by a company or unqualified man who
depends on a qualified man joining him to keep his shop open. A
little diverging from the question, it might not appear to all that
it is only by the qualified men being untrue to themselves that
these concerns keep open. If qualified men refused to associate
with them they could not continue their business. As regards
quack nostrums, I would venture to say that the result of my
proposal would be that before long chemists would combine and
refuse to sell them at all, with the result that by their being dis¬
countenanced by the pharmacist and the medical profession and
relegated to their proper sphere — the grocers and fancy tradesmen
— they Avould soon die out as I firmly believe that all the advertis¬
ing in the world is not so good an advertisement for them as the
vending of them by pharmacists. As regards these quack
nostrums, I would exclude from my hypothesis such
articles as synthetical proprietary remedies and proprietary
articles used only at the dispensing counter, which are introduced
to the medical profession by good pharmacists, and may find favour
as a distinct advance in pharmacy, although they often become
dead stock to the pharmacist ; there are disadvantages to which we
must bow. I refer in my hypothesis to the ordinary preparation
which the pharmacist of to-day simply retails over his counter
intact at a small profit like an ordinary tradesman : that
should not find a place in his shop at all. Certainly occasionally a
medical man orders a preparation of which he is totally ignorant
concerning its composition, but I am pleased to say it is the excep¬
tion and not customary, as the majority of the medical profession
recognise that by it they not only are promoting the sale of an
article antagonistic to their profession, but are displaying their
own incompetency.
Kilbum, N. W. , February 3, 1897. George W. Ray.
Sir, — The wisdom of joining any special movement depends
upon the probability of its success. Has any voluntary combina¬
tion for trade purposes ever succeeded amongst chemists ? The
two chief effects I see from the present attempt are, the perpetual
advance of wholesale prices, and the proprietors’ desire to cut out
the middle man and to deal direct with the retailer, inducing him
to overstock on what he calls best terms for quantity. What does
the average chemist want with five or even two pounds’
worth of everybody’s nostrums ? This arrangement benefits the
cutter chiefly, possibly a few men with surplus cash also, but the
small man is further handicapped thereby. To him, like the
minimum cutting price, it is a delusion and a snare. The only
satisfactory arrangement that can be made is to put all retailers
upon equal terms, quite independent of quantity. This could
easily be accomplished by the proprietors having one definite price
to the wholesale and another for retailers, and this latter price the
same that the middle house would charge them. There would then
be little or no inducement to deal direct. It is infinitely more
convenient for the average chemist to get all his proprietary goods
from one source, and in quantities suitable to his requirements. In
my estimation the proprietors of specialties take it too much as a
matter of fact that pharmacists must supply their articles on
demand. It is true the majority of retailers seem not only to
second this state of affairs, but by their conduct to say they are
quite incapable of carrying on their business on personal and
independent lines, justifying their tactics by the excuse that they
must do as their neighbours do.
Undoubtedly advertisements make a demand for proprietary
articles ; but as a pharmacist I protest against the theory that
makes me a mere distributor of other people’s goods, and in
practice I object to be such, except at good remuneration.
Therefore (with the exception of the jubilee year, when I did a
little sensational advertising) for the twenty-five years I have
been in business here I have refused to cut patents beyond allowing
the medicine stamp or its equivalent to cash customers only, off
those articles which, when that is done, still leave a profit of
about 3 d. in the shilling. All those Is. 1 \d. proprietaries, the
wholesale price of which has been raised beyond 10s. 6 d. a dozen, I
refuse to stock. The list is getting a long one. When I came
into this district there were four chemists, now there are seventeen
including three stores. I believe I am the only one that continues
to get anything like full prices. The question of substitution
does not enter into the matter. My customer hears my explana¬
tion and is free to take what I suggest, or to go elsewhere for what I
do not keep. In the long run I am sure I lose neither money,
self-respect, nor the goodwill of my customer. If the pharmacist
is to advance in the estimation of the public it will not be by
cultivating an increase in the sale of quack medicines.
When behind every chemist’s dispensing counter there is a well-
furnished pharmaceutical laboratory, in which are made nearly all
the preparations in his shop ; when the still, the balance, the
microscope, etc., are as constantly and familiarly handled by him
as the pestle and mortar ; then, perhaps, the public, both medical
and lay, will see in him something beyond a storekeeper or even a
dispenser of physicians’ prescriptions. The apprentice or assist¬
ant may then prepare for his examinations without feeling it will be
so much time and money wasted. Let every man, opening a new
business or purchasing an old one, invest an extra hundred pounds
in that way, some portion of which might be saved from elaborate
show cases and expensive window fittings. He will never regret
it. Using to its full capacity that method, may he not, Sir, find, to
a great extent, the key to the success of the “ historic houses ” of
London and the provinces, which are at once the envy and admira¬
tion of every aspiring pharmacist.
Upper Tooting, S. W., February 6, 1897. Jno. Ingham.
A Personal Complaint.
Sir, — In your report of the Midland Pharmaceutical Ball, it
states that “the general arrangements were admirably carried out
by Mr. Charles Thompson and Mr. J. C. Mackenzie.” On a circular
sent to me by the latter gentleman, after it was over, Mr. Thomp¬
son’s name appears as “Hon. Sec., Ball Committee,” and is signed
by him at the end. Therefore I concluded, and think I am right
in presuming, he did act as such and therefore is responsible for
the position. I find upon referring to the annual report that there
are only one hundred and sixty-five members of the Association ;
therefore, if four hundred circulars were sent out locally, how is
it the Hon. Sec. , whose establishment is not half a mile from mine,
omitted to send one to me ? My grievance is not that I have
missed the opportunity of attending the ball, but, as a member of
the Association, I feel that as a matter of right, not to say of
courtesy and friendliness, I should have received one of those pre¬
cious four hundred circulars. Perhaps Mr. Thompson will kindly
explain why I was allowed to stand out in the cold and left to
grumble at his “ admirable arrangements.”
Birmingham, February 5, 1897. John Onion.
Gtjaiacum Resin.
Sir, — I can corroborate Mr. Smith’s “ note on Guaiacum Resin”
(ante p. 101). In July last when making tr. guaiaci am., curiosity
prompted me to weigh the residue which, I found, amounted to*
180 grs. (= 13*7 p.c.) from 3 oz. Christison (on Jahn’s analysis)
gives “ 11*7 of bark, wood and impurities” as the percentage of
insoluble matter. Mr. Smith is wrong, however, in giving the
B. P. credit for noting “ the limit of insoluble debris in benzoin,”
as it does not even mention the presence of foreign matter.
Squire’s ‘ Companion ’ and other extra-official works do so but
without limitation. I endorse his suggestion.
Glasgow, February 6, 1897. Thomas Dunlop.
*„* In fairness to Mr. Smith, it must be pointed out that, according to the B.P.
benzoin is “soluble” in rectified spirit and in solution of potash, that is to
say practically entirely soluble.- — [Editor Ph. J.]
Help for Major Students.
Sir, — By the introduction of a page for Major students, as-
suggested by Mr. Smith, I am sure you will bring into the Society
a large number at present taking no interest in it. A Minor man
feels he would like to proceed further with his study but the fact
of having to be away from business for some six months makes him.
give up the idea of doing so, with the result that he never gets any
further. I myself have found numerous points which could easily
be explained in such a page. It is disgraceful to see so few
candidates entering for the examination, and I think the Society
should do all in their power to induce Minor men to take the final,
which not only gives a more professional standing, but induces men
to support the Society.
Plymouth, February 7, 1897. J. Arthur Buckley.
Sir, — I desire to add my testimony to that of others in regard to
the Pharmaceutical Journal, which I find not only interesting as a
medium of trade news but also useful in many other ways. I trust-
you will see your way to add a “Major Page” to the already
140
PHARMACEUTICAL JOURNAL,
[Feb. 13, 1897
popular “Students’ Page,” which would be a very great boon-
indeed, because one has not always the means nor the time to
attend classes. Your Law and Parliamentary Intelligence is
quite up to date, and I am especially pleased to learn that the
Early Closing Bill is once more to the front, as well as the Half-
Holiday Bills, which also aim, though in a less degree, at the
shortening of hours. It may interest you to know that in this
district, where there are three chemists, the third and I endeav¬
oured to get No. 2 to close earlier, but without effect, so you see
unless by Act of Parliament it will scarcely be possible to obtain
shorter hours. I also wish to ask your assistance in regard to two
or three queries which I subjoin.
February 8, 1897. W. W. (80/15).
*** As has already been stated the needs of Major students are being borne in
mind, and matter of special interest to them will appear shortly. Meanwhile,
we shall be glad to receive practical suggestions as to suitable directions
in which assistance may profitably be given. — [Editor, Ph. J.]
The Preliminary Examination.
Sir, — I notice at Plymouth five candidates presented themselves
for examination re the Preliminary, and only one passed. This is
far and away the worst record of any of the whole lists of towns.
I am anxious to know if there is any cause for this other than the
students being behind their fellows in general knowledge. I am
told there is, and that is my reason for asking for an impartial in¬
quiry. I was told, the day of the examination, the room was not
ready and they had to wait a quarter of an hour, which time was
taken out of the time allowed for arithmetic. Now, this can be
easily ascertained. If the boys’ papers were good with this one
exception, and it be found their time was short, then I think their
ease should be re-considered. I have no personal knowledge of it
myself, but was told on the day by one that has failed that he felt
sure he did all well except arithmetic, for which he had no time.
I hold if they started a quarter of an hour later they should con¬
clude a quarter of an hour later, giving full time to each subject.
Bodmin, February 5, 1897. Richard T. Cardell.
*** The Superintendent of Examinations for the Plymouth District informs
us that, though the room was not ready when he arrived, it was ready at 11 a.m. ,
and the envelopes were opened and papers delivered at that time, according
to the rules ; consequently the candidates were allowed the full time. More¬
over, it is pointed out, that if the candidates had been delayed a quarter of an
hour, which they were not, it is very strange that the time should have been
deducted from that available for answering the arithmetic paper, on which
work is not commenced until 12.30 p.m., as it is the Latin paper which is given
out at 11 a.m. This statement of facts is supported by letters received from
ar-Plymouth candidate and from the manager of the premises where the
examination was held, and seems effectually to dispose of the complaint
voiced by our correspondent.— [Editor, Ph. /.]
Business Ways that are Dark.
Sir, — The other day I received a parcel by post. The contents
were packets of cachous. I could not understand what it meant,
seeing I had never ordered such. However, there followed in a
day or (;wo a letter enclosing invoice for same, requesting I would
give the goods a prominent place on my counter. Now, after being
in business over thirty years, this “ Sam Slick ” way of doing
business did not agree with my notions of free trade, so I resented,
and returned the lot to await my orders when wanted. This is
another Yankee notion come over the water, and I would like to
ask the British chemists not to submit to this mode of doing busi¬
ness. If they do, all independent spirit will be sapped out of
them. The chains are tightening now, and we will soon be all
tied houses to enterprising Americans. This new cachou company
has mistaken the character of the British chemist ; as a rule, we
are above the “soda fountain” business — the mainstay of the
American pharmacist, and we can understand the usefulness of
a display of cachous on the counter of a drug store. Long may we
be spared from such a necessity, and I ask my fellow chemists to
put their foot down on the “ sale and return ” business. It never
pays in the long run, and causes disputes and heartburnings.
February 6, 1897. “ Anti-Soft Sawder ” (79/41).
OBITUARY-
Dadley.— On January 13, Elijah Dadley, Chemist and Druggist,
of Nottingham. Aged 69.
Miller.— On January 27, Charles Stewart Miller, Chemist and
Druggist, of Hampton Wick. Aged 69.
Stevenson. — On January 27, William Stevenson, Chemist and
Druggist, of Todmorden, Lancs. Aged 68.
Lewls. — On January 27, John Phillip Lewis, Chemist and Druggist,
late of Crawford Street, London. Aged 54.
ANSWERS TO QUERIES.
Mustard Seeds. — Black mustard seeds contain myrosin and
potassium myronate (sinigrin) ; white mustard seeds contain
myrosin and sinalbin. Refer to Maisch’s 1 Materia Medica ’ or
‘ Pharmacographia ’ for information on such points as this.
[Reply to S. H.— 78/27.]
Liq. Strontii Bromid. — Solutions of the lactate, bromide, and
iodide of strontium are prepared in France of a strength of 100
grammes to 500 grammes of water, but we are unable at the
moment to trace any official formula for liqour strontii bromidi.
[Reply to C. E. T. — 80/29.]
Air-Bubbles in Slides. — If you follow Cole’s slow or exposure
method of mounting in balsam, as described in the latest edition
of ‘ Modern Microscopy,’ you are not likely to be troubled with
air-bubbles. In cases, however, where bubbles do appear, you can
easily get rid of them by leaving the slides in a slow oven for a
short time. A small air oven gives as good results as anything.
Refer to note on page 1007 of the Journal for June 10, 1893.
[Reply to E. D.— 78/28.]
School of Pharmacy. — There is no school connected with the
Pharmaceutical Society except that at 17, Bloomsbury Square,
London, and the school prizes are only available to those who study
there. The Council examination prizes, however, may be competed
for by anyone who was an Associate of the Society at the time of
passing the Major examination. Refer to the Society’s Calendar
for details. [Reply to Pharmacognosy. — 78/26.]
Poultry Powder. — The sample you send is not at all like the
formula we gave ; in fact, your stuff contains no definite chemical
salts, it appears to be chiefly a “meal” powder. The principal
ingredients are pea meal and buckwheat meal. That the addition
of two teaspoonfuls to a pound of food will really make the poultry
lay is problematical. Probably it may exert a suggestive influence
on the minds of the hens, or of their owners. There is little doubt
that a condimental powder containing carbonate of calcium, i. e. ,
oyster shells, and sulphates of iron and sodium has a beneficial
action, giving good coloured yolks and thick hard shells. This we
have proved by practical experience. Pea meal itself mixed in
liberal proportion with hot mash of middlings is an excellent
egg-promoting food, probably from its richness in nitrogenous
matter. — [Reply to G. M. — 78/17.]
British Pharmaceutical Conference. — The late G. F. Schacht
suggested, on the occasion of a meeting at Bristol in August,
1852 (see Pli. J. [1], xii., 123), that the annual meetings of the
Pharmaceutical Society should be held at the various towns of im¬
portance where the members resided. Subsequently, the idea that
pharmaceutical meetings should be held annually in different locali¬
ties cropped up from time to time, and ten years later letters on the
subject were published by R. Reynolds, H. B. Brady, and G. F.
Schacht (see Ph. J. [2] iv., 504, 562, and 563), whilst in 1863 the
circular (see Ph. J. [2], v., 58) was issued calling the first meeting
at Newcastle-on-Tyne, where the Conference was duly inaugu¬
rated on September 2 in that year (see Ph. J. [2], v., 145). A
brief account of these matters is given in Bell and Redwood’s
‘ Progress of Pharmacy,’ pp. 219, 220, and 316, but for fuller par¬
ticulars you must refer to our early volumes specified above.
[Reply to R. W. M.— 79/27.]
Staining and Mounting Micro-Objects. — For information
respecting hardening and fixing reagents, stains, clearing agents,
and mounting media, you cannot do better than refer to Squire’s
* Methods ana Formulae ’ (Churchill, 3s. 6 d. ), whilst Cross and
Cole’s ‘Modern Microscopy’ (Bailliere, 3s. 6d.) is very good for
directions regarding manipulation, etc. [Reply to H. O. — 80/2.]
COMMUNICATIONS, LETTERS, etc., have been received from
Messrs. Alikins, Arnott, Austen, Barnes, Bedford, Betts, Brown, Buckley,
Butler, Cardell, Chaplin, Chaston, Clark, Coley, Cracknell, Davis, Dawson,
Dunlop, Duyk, Ennals, Gibbs, Gibson, Hill, Hills, Hudson, Hunt, Ingham,
Jacks, Jackson, Keif, Kerr, King, Kirkby, Kitchin, Lasham, Mackie, McKnight,
Mair, Melliuish, Moss, Oldham, Onion, Ough, Owen, Palmer, Passingham, Pollard,
Roberts, Robins, Roper, Scott, Seward, Shepherd, Stacey, Stainer, Turner,
Typke, Umney, Walker, Woodward.
PHARMACEUTICAL JOURNAL.
141
20. 1897]
i Co
/THE ALLEGED CONVERSION OF CINCHONINE
\ 19 pr: r ; p*TO CINCHONIDINE.
BY DR. B. H / PAUL AND A. J. COWNLEY.
- epter tainAcl by many chemists as to cinchonine being
stereoI'SQQaerigl^iHfcinchonidine, and quinine with quinidine, have
not hitherto resulted experimentally in the conversion of the one
alkaloid into the other. When cinchonine is treated with acids it
is said to be converted into various isomers, but not into cincho¬
nidine. In experimenting, however, as to the action of alkalies on
the cinchona alkaloids, Herren W. Koenigs and A. Husmann claim,
in a paper recently read before the German Chemical Society
(Berichte, xxix., 2185), to have converted cinchonine into cinchoui-
dine by the long continued action of boiling amyl-alcoholic potash.
It is hardly necessary to say that this would be a very important
chemical fact if it could be substantiated.
The method adopted by the authors was to treat 4 grammes of
cinchonine for from 15 to 16 hours with 2 grammes of potash dis¬
solved in 120 cubic centimetres of amylic alcohol. After the
action, the bases were removed from the amylic alcohol with
hydrochloric acid, and the bases obtained by precipitation with
soda were dissolved in the least possible quantity of boiling
alcohol. After cooling, about 1 gramme of unaltered cinchonine
crystallised out. The mother liquor was neutralised with hydro¬
chloric acid, the alcohol expelled, and after dilution with
water to 150 C.c. , 5 grammes of Rochelle salt were added. The sepa¬
rated tartrate was decomposed with soda, and the alkaloid crystal¬
lised from weak alcohol. In this way 0 ’2 gramme of base was obtained,
which, according to the authors, had the melting point, rotatory
power, and composition of cinchonidine. An organic analysis gave
numbers corresponding to the formula for cinchonidine, C19H22N20.
A considerable part of the cinchonine is also said to be con¬
verted into bases which are soluble in ether. Knowing from expe¬
rience when dealing with the cinchona alkaloids of the great diffi¬
culty in separating one cinchona alkaloid from another in order to
obtain an alkaloid of perfect purity, we were somewhat sceptical as
to the result being a conversion of one alkaloid into the other,
more especially as Koenig and Husmann merely claim to have con¬
verted 5 per cent, of the cinchonine into cinchonidine. Also the
methods described for identification of the alkaloid are not very
discriminating, especially in attempting to identify the alkaloid
from the results of the percentage of carbon and hydrogen obtained
in an organic analysis.
For the purpose of examining the statement of Koenigs and
Husmann we have carried out the treatment of cinchonine with
potash exactly in the manner described by them. Four grammes
of pure cinchonine were dissolved in 120 C.c. of amylic alcohol
containing 2 grammes of actual KHO, and the solution boiled for
seventeen hours. The alcoholic solution was then extracted with
hydrochloric acid and the acid liquor shaken up with ether and
soda in order to obtain the bases soluble in ether described by the
authors. The ether would probably also remove a little cinchoni¬
dine if present. The bases which were insoluble in ether were' treated
with boiling alcohol, cooled, and filtered. In this way we obtained
three fractions: — (1) soluble in ether; (2) soluble in alcohol ; (3)
insoluble in alcohol. The portion soluble in ether amounted to
0-105 gramme, and was chiefly amorphous, with a few crystals. It
was converted into neutral sulphate and diluted with water to 10
cubic centimetres. It gave no precipitate of tartrate of cinchoni¬
dine from that dilution, and the crystals from ether proved to be
unaltered cinchonine. The portion soluble in alcohol amounted to
0'47 gramme. It was similarly treated, but it gave no precipitate
Vol. LVIII. (Fourth Series, Vol. IV.). No. 1391.
of cinchonidine tartrate from an aqueous solution of 70 C.c. The
fraction insoluble in alcohol when converted into a salt gave no
cinchonidine tartrate from a dilution of 130 C.c.
From these results it is apparent that we were unsuccessful in
our endeavour to corroborate Koenigs and Husmann’s statement
as to the possibility of converting cinchonine into cinchonidine by
the action of dilute potash. On the supposition that the base
obtained by them was really cinchonidine, it must be presumed
that the cinchonine operated upon had not been sufficiently puri¬
fied. It is well known to quinologists that the cinchona alkaloids
are vei’y prone to form double compounds with each other, either
as alkaloids when separating from various solvents, such as ether
and alcohol — the latter being used by the authors — or as salts
from aqueous solutions. Cupreine, for instance, which we isolated
from Remijia pedunculata forms a compound with quinine, viz.,
homoquinine, which reacts whether as an alkaloid or as a salt,
differing in many respects from either cupreine or quinine respec¬
tively, and is only separable in the manner we have previously
described (Pharm. Joum. [3], xv., 221 and 401). For the pure
cinchonine used in our experiments we are indebted to Mr. W. G.
Whiffen, of the firm of Messrs. Whiffen, of Lombard Road, Battersea.
FERROUS PHOSPHATE.
BY E. J. EVANS,
Pharmaceutical Chemist.
Two years ago I was induced, after reading the paper on the
above preparation by Mr. G. Coull, B.Sc. , to experiment with a
view to improving the percentage of hydrated ferrous phosphate in
this preparation.
The first experiments were made with B.P. proportions, and
yielded very disappointing results, but I found by adopting some
modifications in the process from time to time that the percentage
gradually increased and led me to believe that ultimately a pure
salt might be made. One of the first points which was observed
in the washing of the precipitated ferrous phosphate was that pro¬
longed washing invariably made the percentage less, and decanta¬
tion was much preferable to washing the precipitate on the calico
filter.
An experiment to prove how many decantations were necessary
established the fact that after standing twenty-four hours the first
decantation contains over 80 per cent, of the sulphate of sodium
formed, and that a second decantation yielded a phosphate of iron
which gave no precipitate with barium chloride. It was also found
that further decantations deteriorated the resulting salt.
In another experiment, to determine whether the preparation
should be squeezed strongly in calico after the second decantation
and then dried on the water-bath, or whether it should be poured
in a thin layer on the water-bath and dried, the result showed 1 per
cent, in favour of the former, but extended trials are required for
confirmation. The powders obtained were light blue in the first
and dark blue in the other.
The degree of temperature to which the water-bath was raised
had also an influence on the salt, and that the temperature of
100° F. to be the most suitable. Ferrous sulphate was first tried
until a preparation containing 80 per cent, of hydrated ferrous
phosphate was obtained. Ferrous chloride wae then tried, the
idea being that sodium chloride could be more easily washed out
than sodium sulphate.
The difficulty, however, in this case was that the ferrous chloride
had to be prepared, and that it was not so easy to calculate its
strength and the quantities required.
142
PHARMACEUTICAL JOURNAL.
[Feb. 20. 1897.
The results showed preparations from 80 per cent, to 90 per cent,
hydrated ferrous phosphate, and it is possible that had I made the
same number of experiments with the chloride as was made with
the sulphate, better results would have been obtained.
Even the recently precipitated ferrous phosphate shows ferric
impurity.
Ferrous acetate was also tried instead of sulphate, the reason
for the adoption of this salt was that alcohol might be used as a
oon-oxydisable solvent of the alkaline acetate formed.
The preparation of this salt in the pure state was found to be a
difficult matter, and after two or three experiments was dropped
for similar reasons to that of the chloride. Therefore, later
(experiments were made with ferrous sulphate or ferrous ammo¬
nium sulphate, either alone or with sodium acetate or sodium
bicarbonate.
One disadvantage the bicarbonate has is the C02 given off when
mixing the two solutions, i.e. , ferrous sulphate and sodium phos¬
phate, together with the sodium bicarbonate, and the same applies
when ferrous ammonium sulphate is used.
I select three comparative experiments to show the method
•employed and the results obtained
1. FeS047H20 . 10 grammes.
Na2HP0412H20 . 10 „
Each salt was dissolved in 150 C.c. cold water, then mixed in a
flask, stoppered and well shaken, left two days, then the clear
solution decanted in an atmosphere of CH4 gas (coal gas), and the
flask filled up with water, well shaken, allowed to settle, decanted
again, then transferred to a calico filter, squeezed strongly, trans¬
ferred to a water-bath, heated, not exceeding 120° F.
•246 gramme required 44 C.c. KCr04, 1 '94 gramme to litre.
= 90 '8 per cent, hydrated ferrous phosphate.
•249 gramme required 45 '5 C.c. KCr04, 1‘94 gramme to litre.
= 91 '7 per cent. Fe32P048H20.
2. Na2HP0412H20 . 10 grammes.
NaHCOs . 2
(NH4)2Fe(S04)2eH20 . . 12 ’’
Same process as 1.
98 per cent. Fe32P04SH20.
Kept in stoppered bottle and analysed fourteen days after—
90’8 per cent. Fe32P048H20.
2. (NH4)2Fe(S04)26H20 . 12 grammes.
NaA . 2
jtfaoHP0412H20 . 10
Same process, but kept two days longer in flask before
decanting —
96 -8 per cent. Fe32P048H20.
,A week later, kept meanwhile in open capsule — •
92-9 per cent. Fe32P048H20.
These results would seem to show that the hydrated ferrous
phosphate rapidly deteriorates in strength, but this is not
altogether the reason for the differSnce in results.
It is quite possible that the bulk of the powder was not dried
throughout to the same extent, and that a small amount of
moisture had remained in it. A sample made three months ago,
and kept since in a stoppered bottle, shows very little change.
I find that the washing by decantation is more easily done if
two or three days is allowed for the precipitate to settle ; the
water clears very rapidly for the second decantation.
The quantity of ferrous phosphate obtained is about one-half
the theoretical quantity, however, this may be accounted for from
the small quantities used.
I would suggest the following formula as suitable for the
next B.P. : —
Iron Ammonium Sulphate . . . . . 12 parts.
Or Iron Sulphate . 8 ,,
Phosphate of Sodium . 10 ,,
Sodium Acetate . 2 ,,
Distilled Water . 600 ,,
Dissolve the iron salt in 150 parts of the distilled water, and the
phosphate and acetate of sodium in another 150 parts, mix the
solutions together in a vessel or flask fitted with air-tight cork, and
of such capacity that these solutions when mixed should fill it.
Well shaken for some time, then set aside in a dark place for two
to four days, decant the clear solution, fill the vessel with remainder
of water, and after standing twelve hours, decant the supernatant
liquid, transfer precipitate to a calico filter, squeeze strongly, and
put the precipitate on to a water-bath heated not exceeding 100“
F. , stirring meanwhile with a glass rod.
The resulting powder should be kept in a stoppered bottle free
from light, and should contain at least 90 per cent, of hydrated
ferrous phosphate (Fe32P04,8H205).
Tests. — Soluble in acids, insoluble in water. BaCl2 should not
give a precipitate with it when dissolved in HC1. Should require
of K2Cr207 standard solution sufficient to correspond with 90 per
cent, hydrated ferrous phosphate.
The solution, treated with tartaric acid and ammonium mag¬
nesian mixture, should give a crystalline precipitate. This
dissolved in dilute HC1 and sodium acetate added should yield
with a standardised uranium solution equal to 13 per cent. P206.
A SIMPLE METHOD OF WATER ANALYSIS.
A Simple Method of Water Analysis, especially designed for the use of
• Medical Officers of Health. By John C. Thresh, M.D., D.Sc., etc. Pp. 47.
Price 2s. 04. London : J. and A. Churchill. 1897.
This little work is specially intended for medical officers of
health, who in “rural districts find it impossible to efficiently dis¬
charge their duties without some knowledge of water analysis
..... as cases are almost daily arising in which a medical
officer desires to know something of the character of a water, and
he is well aware that it is useless recommending his authority to
send a sample to an analyst, so that unless he himself can under¬
take the work it must remain undone.” The methods described
are such as can be carried out by non-experts with the simplest
possible apparatus, so that the analysis may be conducted in the
neighbourhood of the well or other source of supply, and even on
so small a quantity as a pint of the water. The chemical
reagents used are kept in a compressed form as soloids,
which have been prepared for the author by Messrs. Bur¬
roughs, Wellcome, and Company, and have been found to be
exceedingly uniform in composition and in every way satisfactory.
For the determination, for example, of chlorine a soloid of potas¬
sium chromate is added to 70 C.c. of the water under examination,
then soloids of silver nitrate until the red coloration is obtained.
As each soloid of silver nitrate corresponds in its indication to two
grains of chlorine per gallon, the amount of chlorine in the water
is very 'readily ascertained. In the same way the other factors of
use in judging of the potability of a sample of water from its
chemical side are determined by the addition of the respective
soloid reagents. In this manner are estimated free ammonia, chlorine,
nitrates, nitrites, hardness, lead, zinc, iron, copper, and oxygen
absorbed.
With the exception of the test for free ammonia which is apt to
be very fallacious when the Kessler re-agent is added to the water
direct the use of soloids in water analysis is very ingenious. Com¬
parisons made by this simple method with the ordinary methods
Feb. 20, 1897.]
PHARMACEUTICAL JOURNAL.
143
of water analysis show the results obtained to be fairly concordant.
Twenty-two examples are given as a guide, and an opinion is
expressed from the data as to the suitability of each water for
domestic purposes which will be of service to those unfamiliar with
the deductions to be drawn from the analytical results.
Ur. Thresh, however, has not much faith either in chemical or
bacteriological examination of water, for “ bacteriology, like chemis -
try, may tell us something of impurity and hazard, but neither can
be depended upon to determine with certainty whether a water is
actually injurious to health.” “It is far more important to
examine the source of a water than to analyse it.” In other words,
then, in deciding the question as to the potability of a water, the
sanitary inspector is of far more importance than the analyst,
whether chemical or bacteriological. Although we are in accord
with Dr. Thresh as to the futility of the bacteriological examina¬
tion of a water as is usually carried out by merely counting the
number of colonies per cubic centimetre of the water without
regard to their pathogenic import, we yet think that a chemical
examination judiciously conducted is of great importance, and for
this reason we believe this work will be of great use to medical
officers of health who, on account of the supineness of their local
authority, are unable to consult more efficient experts.
CHAPTERS IN PHYSICAL SCIENCE.
Short Studies in Physical Science : Mineralogy, Chemistry, and Physics. By
Vaughan Cornish, M.Sc. Pp. 230, illustrated. Price 5s. London : Sampson
Low, Marston and Company, Limited, Fetter Lane, Fleet Street, E.C. 1897.
With the advance of science and increasing specialisation of
exact knowledge of phenomena, a wider field presents itself for
writers who are capable of thoroughly digesting the numerous
explanations of apparently complicated arrays of facts,
and presenting the resulting condensations to a public
with limited leisure to consider 'matters regarded, rightly
or wrongly, as being far outside the ordinary range of
everyday life. Mr. Vaughan Cornish has had much experience in
this direction and his varied contributions to the scientific press,
now reprinted in book form, have appealed to a wide circle of
interested readers. That they are all well deserving of publication
in this more permanent form is beyond doubt, and much good is
likely to accrue from readers of these attractively written essays
being tempted to investigate the matters treated of for them¬
selves. The chapters, each of which is complete in itself, are six¬
teen in all, and he who has read and mastered the whole will
possess a fairly comprehensive grasp of the wide scope of
the physical science of to-day. In the section on “Mineralogy”
are chapters on crystals, mineral synthesis, diamond mining and
diamond making, the subject of crystallography being brought well
up to date by a summary of Moissan’s important work. Under
the heading of “Chemistry” we are treated to disquisitions on
elements and atoms, chemical classification, chemical symbolism
and organic chemistry, chemical activity, chemical manufacture,
and food. The author is thus enabled practically to cover the
whole ground from the time of Lavoisier down* to the present
day. The final section, on “Physics,” treats of artificial cold,
phosphorescent bodies, the magnet, aether, and the Rdntgen rays,
concluding with chapters on great astronomers and natural
philosophy. It will be seen, therefore, that the book deals very
comprehensively with all the problems and discoveries of import¬
ance in physical science that occupy a prominent share of atten¬
tion at the present time, and it may be stated that whilst the
subject matter of the essays has been well selected, their style is
excellent, and they will well repay perusal by both past and present
students of physical science.
THE PROFESSION OF PHARMACY
From an Assistant’s Point of View.*
BY W. MAKEPEACE LOCKE.
On the evening of Wednesday, February 20, 1895, I had the
pleasure of reading a concise account of the “ Profession of
Pharmacy ” from an apprentice’s standpoint. That effort embodied
the life history of a very dear friend of mine, who about a year
previous had gone “to swell the ranks above.” Extracts had been
taken from his well-kept diary, and were elaborated by me with
the purpose of exposing certain anomalies which existed in those
days in the “ profession.”
Looking back to the time when the paper was written and re¬
reading the article itself, I am forced to admit that it had many
flaws — flaws which even now make me blush. Notwithstanding
this fact I am here again to-night, after a lapse of nearly two years,
to see old and well-known faces and to present to you the same
subject under a new aspect. Although not now a member of the
profession of pharmacy, it yet occupies a very warm corner of my
heart, and I can look back with extreme pleasure at the many
pleasant evenings I have spent within these walls.
The subject we have to discuss — this profession of pharmacy —
is very wide, presenting, as it does, so many points of view, and I
would at this stage humbly ask permission to reproduce for you
the other aspects of the case for delivery on future occasions.
This, I trust, you will grant.
Those of you who were present two years ago, the first time the
Association had met in this hall, may perhaps remember some of
the selections from the diary. Bottle washing, syphon carrying,
window cleaning ; harsh words, stormy scenes, vengeful vows ;
this is the life of the apprentice chemist. For him the profession
has no bright side, he longs for release from his troubles.
This is then, in a few words, the gist of my last paper, and well
do I remember the opinion of the meeting on that occasion, that
“while the conditions of apprenticeship were too frequently
highly unsatisfactory and as a rule capable of much improvement,
especially in regard to time for study, many of these so-
called menial occupations formed an essential, though perhaps
unpleasant, part of a complete training in practical pharmacy.”
One of the members who took part in the after discussion stated
as his opinion that I personally would modify my ideas on the
subject. Although at that time I denied even the remote possi¬
bility of doing so, I am bound to confess that now my views are
altered. In justice to his prediction, let me say that my belief
at present is that these various menial duties do constitute a very
necessary part of the training of the embryo pharmacist ; but let
me also point out the fact that my outlook is distinctly different,
calling forth, consequently, a change of opinion. As apprentices
we groaned under the heavy yolk, making as much outcry as we
dared ; as assistants we conveniently forget those times ; and as
masters they are but specks on the horizon of the past.
Yes ! as assistants we have come through the trying fire of ap¬
prenticeship, and, eager to leave it behind, thrill with pleasure in
our new capacity.
From this new capacity, therefore, we shall analyse the “pro¬
fession of pharmacy,” and conduct our investigations in every
direction, tabulate our results with a strict regard for truth, and
yet treat the matter in the highest possible spirit. Keeping these
remarks then well in view, no offence can possibly be taken where
none is intended ; and If at times the shoe do«s pinch it is simply
the result of an awakened conscience ; for I would ask you to
remember that the material for this essay has be been gathered
principally from various districts of England and Ireland, and that
only a few scraps are Scotch.
First, then, it is obvious to all that, from the points of
view of the assistant and apprentice, a profession pharmacy cer¬
tainly is not; and no candid apprentice, no candid assistant even,
has been found to assert that it is. The “professional ” view is
only in vogue with a certain class of the employers, who, after all,
are no better than their neighbours. Even from their look out, 1
fail to see any difference between the chemist’s business and any
other, except that it embraces a host of trades under a single
designation. Barber’s utensils, confectioner’s goods, grocer s
specialties, and tobacconist’s luxuries all are found, as a rule, in
chemists’ shops. This state of things is distinctly unprofessional
and simply points to a huge monopoly, a grand contrivance for the
coining of money and the principle of aggrandisement carried to
excess. _
* Taper read before the Edinburgh Chemists’ Association.
144
PHARMACEUTICAL JOURNAL,
[Feb. 20, 1897
There is, however, little laughable in the “ profession,” beyond
the sarcasm of the term. At the same time, as a means of liveli¬
hood it is distinctly good, and to a man with brains and capital
still leads on to fortune. But one must be up to date and keep an
eye on one’s neighbours in the “profession,” for in pharmacy, as in
everything else, the weakest go to the wall. I would boldly say,
“Away with all false sentiment.” Call a spade a spade, and.
pharmacy a vocation, a business, a calling, a trade, anything, in
fact, but a “profession.” All labour is honourable. A rose by
any other name would smell as sweet, and if one man likes to call
his shop a “ pharmacy ” and himself a pharmacist, when the man
with the same qualifications and more brain, perhaps, calls his
place a ‘ ‘ drug store ” and himself a druggist, I would not spend
ten seconds in arguing which man was wrong and which was
right, for, as a matter of fact, neither is wrong if neither is right.
Discussion is silly, puerile, unworthy of being given time for
ventilation, for ventilation would not advance the matter one whit.
This leads us to the consideration of the second part of the sub¬
ject, “ Pharmacy, from an assistant’s point of view.”
Here, again, we are beset with difficulties, different methods,
different opinions, and different assistants; each one with his
little peculiarity. But at one fell swoop we can divide the assist¬
ants into two great classes : those who are qualified, and those
who are unqualified ; and of these, I shall ask you to study with
me first, the “great unqualified,” taking as a type a newly-
fledged ex-apprentice.
On most points, his ideas of pharmacy are simply those of his
late employer, making due allowance, of course, for his special
modifications. He has hardly yet had time to recover from the
stings and insults which had been heaped on him during these
long years ; and now, with much bitterness of spirit, he seeks an
appointment where he shall be tolerably recompensed, and at the
same time get a few hours to devote to private study, to prepare,
in a word, for the Minor Examination of the Pharmaceutical
Society. Let us follow him on his quest ; and as we walk along,
we have ample opportunity to study him physically, mentally,
and morally.
Rather under twenty years of age, face pale but interesting,
eyes small and deep-set, head bowed down, shoulders bent, knees
not over-strong, these are the features we grasp almost at a glance.
Add to this a generally shabby attire, an attire which has evidently
seen better days, and we complete the physical picture of one who
is but the ghost of his former self. Long hours, hard and incessant
labour, and insufficient exercise, at the time when the human
machine needs a little oil, have wrought, with deadly effect, havoc
on all the systems of his body. What he requires is a holiday, re¬
curring at regular intervals, the shorter the better. Among
chemists’ employes, I fancy, this is a consummation devoutly to be
wished.
Mentally healthy, his brain is stored with knowledge of divers
kinds, and if these be used aright, he will in time be in a position
to render himself a valuable ally of the physician. If, on the other
hand, he puts his knowledge to an improper or illegal use, he is
equally fit to associate with criminals and to enjoy a pension from
the State for the rest of his natural life. Thus what he requires
is a real friend, a guiding hand, to repress his evil habits and
passions, and to encourage his good qualities, so that he may ulti¬
mately blossom out as an honourable member of Society.
His essentially moral condition we shall defer to a more con¬
venient season, for he has now stopped suddenly to pull his jacket
straight and make sundry small improvements in his personal
appearance ; then, evidently satisfied, he boldly enters a spacious
establishment bearing the sign of the “mortar and pestle.” Here
we may imagine him undergoing a severe cross-examination at the
hands of the proprietor with regard to age, habits, sobriety, and
remuneration ; finally he is installed as junior unqualified
assistant at the princely salary of eighteen shillings per week, no
prospect of a “ rise,” work to begin at once. With regard to
time for study, Mr. Pharmacist would arrange about that after
the present pressure of business was relieved. What cared he
though the course of classes was just beginning? He was satisfied,
let the junior wait. Truly this is a selfish world !
For some little time, then, all goes well. But friendly political
discussions arise between the qualified and unqualified hands ;
friendly political discussions give place to angry political dis¬
cussions, angry political discussions to angry personal discussions,
and from angry personal discussions it is but a step to blows.
Discontent has eaten its way in, rebellion has invaded the pharma¬
ceutical sanctity of the place and now reigns supreme. But what
does Mr. Pharmacist say ? Oh, well he takes a middle course,
pleads with each in turn, and patches up the matter ; for in truth
lie is in possession of a cheap working piece of humanity and does
not wish to part with him. Begone ! all ye who practise this
vice ; for what a baneful effect it has on young untutored minds.
Our junior, owing to necessity, for want stared him in the face,
had contracted for wages which he deemed inadequate to his
needs. He feels himself thoroughly oppressed with labour, and
thinks he is entitled to rectify the balance of things by what may
be fitly termed “ Private compensation,” for which his position
affords him admirable facilities ; for is not the labourer worthy of
his hire ?
This little game, which comes under the category of the
“consistent central principle” (to be explained hereafter), does
not continue for an indefinite period ; for being caught in the act,
a few stern words are uttered by his employer, and as a
consequence, our friend, weeping bitterly, departs for a healthier
clime, to roam in pastures new.
We cannot do otherwise than regret that the career of such a
promising young man was so suddenly cut short ; ah, where was
the guiding hand ? What brought him to such a pass ? Shall I
tell you ?
It was the example set by his superiors, and such an example
will occur further on. This, gentlemen, is no fiction, and is rather
abridged than overdrawn.
If you can imagine to yourselves a young man, a newly-fledged
ex-apprentice as before, steadfastly resisting all temptation,
pursuing his studies with might and main, and at the same time
performing his daily work as a chemist’s junior unqualified assis¬
tant, you have a likeness in your minds of the next character I
wish to introduce.
Let us suppose that as a result of his diligent study, he has
passed his examination with flying colours, and that, by recom¬
mendation, he has obtained an honourable and fairly lucrative
post. He, too, during his apprenticeship has had his full share of
dirty work ; he, too, during the time of his junior assistantship
(that most unenviable post) has had his trials and cares. These
facts, however, are kept in the background, carefully screened
from mortal eyes ; he looks upon them as a horrible nightmare of
the past. What cares he now for these odious reminiscences, as
long as he receives his salary at the appointed time ? As he thus
fondly thinks of the hard cash, visions of a magnificent business
establishment, ideas of marriage, retirement, and a life of slothful
ease spent in the bosom of his family crowd upon his mind until,
fairly intoxicated with delight, he rudely falls from his lofty
perch and awakens to the stern necessities of everyday life. Oh !
foolish man, cease thy day-dreaming, have done building castles ;
rain is impending.
What is it, I ask, but this afore-mentioned “consistent central
principle,” in which self is ever to the front, that causes his
master, when insolvent, to set aside his assets for his own use and
enjoyment ?
According to his own reasoning his master is not guilty of what
is foolishly called fraud, for how could he save himself (and it is
his sacred duty to save himself) from unaccustomed poverty and
pain except by the abstraction of so much of his own property as
he may consider needful to his future maintenance and establish¬
ment in a position of enhanced prosperity and comfort ?
To his poor dependents, all this is, as you may imagine, exceed¬
ingly comforting. Thrown out of employment, thrown out of
house and home, without bread to eat, without money to buy it,
his ambition unsatisfied, his lofty dreams dispelled, surely pharmacy
is not for him.
Again must I tell you, gentlemen, that this is no mere fabrica¬
tion ; every word is truth. It would be easy for me to lay hands
on the parties, but, for obvious reasons, we shall “ let sleeping
dogs lie.”
Now, with such an example from a master, how can we wonder
that the embryo pharmacist is not all he should be ; but if em¬
ployers recognised the responsibility of training up young minds,
many dissolute lives would thereby be spared. Not but that some
are incorrigible ; only, I think, a little gentleness is required, and
a little trouble to find the proper method. I venture to say that
any inconvenience would be amply repaid.
And now, as a change, allow me to trace the career of the suc¬
cessful assistant. Why does the new youth, just out of his teens,
from the isolated village, add to the problem of centralisation in
cities by taking an express single ticket to town ? Why, but for
experience ? His one aim, now- that his term of apprenticeship is
Feb. 20, 1897J
PHARMACEUTICAL JOURNAL
145
*
I
over, is to enter an establishmement where the arts of window
cleaning and bottle washing will be exchanged for a knowledge
of the correct forms of address at the counter, the most approved
methods of dispensing, and the intricacies of modern book-keep¬
ing. Contemporaneously with the acquisition of all this and
more, a kind of evolution may be noted in the subject of our re¬
marks. What may be termed physical metamorphosis gradually
takes place, and the erstwhile rugged son of Albion gives place to
the sleek, suave, and urbane man of the world. I do not say this
is taught him as part of his profession, but granted our subject has
average intelligence, a slight ambition, and a seeing eye, this change
is not long in taking place. He pays more attention to his head ;
he is better groomed than hitherto. He exchanges the turn-down
“ Shakespeare” for the high “Monte Carlo” or other fashionable
collar, and his neckwear generally becomes irreproachable. His
boots are lighter than formerly, and square toes are superseded by
those more or less pointed. A smart morning coat is found in
place of the former jacket, and unmentionables of a light fancy
tweed are worn in place of the heavy Scotch of former days. The
most up-to-date hard felt hat (on Sunday the stove-pipe) is worn
instead of the Glengarry or Balmoral cap with which he came to
town. A pair of gloves and a cheap showy stick complete his
equipment. A taste for the “ weed” is developed, and it may be
taken for granted that his liquid sustenance is not confined to tea,
coffee, cocoa, and soda water. Naturally the gaieties of the city
appeal forcibly to him after the dulness of his native place, so that
in the foregoing rapid generalisation of his concomitants we have
the assistant as he appears a year or so after coming to adorn the
profession of pharmacy in the city. I might almost say that
this evolution is a necessary part of his pharmaceutical ex¬
perience, so regularly is it exhibited by the individual.
From the stand-point of the young man of this type, the
profession, of which I see many honoured representatives
.gathered round me to-night, offers numerous advantages. The
successful assistant is alive to the fact that, to be prosperous in
business necessitates a comprehensive and not merely a superficial
knowledge of human nature, counter routine, and tricky ways.
Well does he know that the man who pleases his employer most is
the unblushing liar, the brazen-faced automaton, and the con¬
scienceless commission-collecting counterman. His conception of
business is easily found, for it simply is another branch of the
same old “consistent central principle.” It is to buy every
article for as much as possible less than its value and to sell it for
as much as possible more. Now, of course, uniformly to effect
this double object he must clearly have always two opposite sets
of statements and arguments ready for production and assertion.
To do this convincingly and well requires extreme versatility,
readiness of resource, presence of mind, and a certain appearance
of genuine, hearty, earnest uprightness. This combination of
powers constitutes true business ability, and to the enviable assis¬
tant is worth a fortune. All the actions, then, of the successful
assistant are pervaded by the same spirit and worked on the same
useful principle.
This is, after all, very nearly the truth. In many places it is
understood that business consists in foisting upon you something
you don’t want, something you don’t need, something you did not
ask for. In others it consists of taking two, three, or four
“ grades ” of goods from the same box, at, of course, graded prices.
It consists of offering as B.P. preparations colourable imitations
thereof in many instances, and in never, never, never letting a
customer go without getting him (or her, as the case may be) to
buy something, the bigger the better. This last is of supreme
importance. Certain proprietary articles are pushed, in season
and out of season, for this little trouble and that great ailment,
are palmed off on unsuspecting “Juggins” with the idea of making
hay while the sun shines, and keeping always in view the same
‘ ‘ consistent central principle. ”
That colourable imitations are sold is well known to you all, and
to illustrate the best colouring agent, which, I believe, seldom
fails, I cannot do better than read to you a short poem which
appeared in the Chemist and Druggist of September 12, 1896.
It is headed “Not Official.”
“ I built a bridge of fancies” — of the “asinoram ” class —
And watched the long procession adown my structure pass
I noted the dyspeptic, the suffering, and the hale,
The nervous hypochondriac, the rosy and the pale ;
And I thought “ What is the secret that has the most avail,
The most important factor that shall scarcely ever fail
To help the anxious pharmacist along his devious way,
To keep the B.P. strengths all right, his honest doubts allay,
Enrich the pale infusion and the tincture that looks thin,
To fortify the essence that has no kola in,
Enhance the rare elixir and give the liquor strength?”
I dwelt on all these mysteries, and thought until at length
■ I went across that bridge myself, in quest of one I knew,
A man of great experience, and years not a few,
An expert in the mystic art of mortar, retort, still,
Alembic, blowpipe, crucible — (his Christian name was Bill) —
To put the burning questions to this ancient man of skill.
And when at last I found him, by a large steam jacket pan —
Like some old Rosicrucian looked this venerable man —
I poured out all my queries on his poor devoted head.
His eye began to twinkle, but never word he said,
Till as I grew more eloquent, and begged him, for the sake
Of “ Auld Lang Syne ” and all the rest, he would the trouble take
From the storehouse of his knowledge such secrets to entrust,
He winked the other eye and said, “ My friend, try sacchar. ust.”
All this, then, comes under the category of “business.” Time
does not permit me to present to you any further idea on the sub¬
ject from an assistant’s point of view. Many other aspects, I
fancy, will suggest themselves to you as they do to me, but I have
already touched on a few typical cases, all of which are full of
suggestiveness, even to the ordinary mind.
Apprentices will here find ample food for reflections ; assistants,
perchance, may not despise the lessons to be learned ; and I would
ask employers, with, however, due deference to their mature
years, to lend an ear and profit by the examples herein set forth.
Lastly, therefore, let us, as before arranged, tabulate our results
with truthfulness and lightness of spirit withal ; let us set forth
side by side the advantages and disadvantages experienced by
assistants ; let us follow that up by drawing our conclusions, and
over our conclusions let us draw the veil.
First, then, from the assistant’s point of view, pharmacy is
clearly not a “ profession,” secondly, to the unqualified assistant,
our first example, pharmacy has been a stone of collision on two
heads, physically and morally ; it rests with himself to make it so
mentally ; thirdly, to the qualified assistant pharmacy may be a
shipwreck on the sea of life, or it may be, on the other hand, but
the stepping-stone to fortune and happiness, at the expense, how¬
ever, of conscience ; these are the chief results at which we arrive,
and the time has come for drawing conclusions.
With your permission, however, I shall frame these myself, as it
is just possible you may disagree with me on certain points-.
The lot of the average chemist’s assistant, like the policeman’s,
is not a happy one, a manager’s place is to be preferred ; however,
assistants will always be in demand, and assistants will always be
in evidence, until that joyful day arrives when every man will be
deemed equal with his neighbour, when there will be no more class
distinctions, no caste questions, no superiors or inferiors. It is
perfectly plain that this state of serfdom or assistantship is
necessary in this age, where capital is pitted against
labour, but it is as plain that this state, for experience’ sake,
is as necessary ; at once, therefore, we take a hopeful view
of the assistant. Without these years he would not be fitted for
paddling his own canoe when he has finally triumphed at the
“ Square ” in London or “ The Rooms ” here in Edinburgh at the
great quarterly separations of the sheep from the goats. Experi¬
ence then is the justification for the existence of the assistant
to-day ; and that experience, necessarily, in different cases, varies
considerably. Again, without mentioning the mere money¬
making aspect of the exercise of the profession, there is the
knowledge that the chemist, in the estimation of the public, is
second only to the medical man or the priest. His influence is
often tremendous in many districts, and that to more than a few
aspiring young fellows counts far more than a fat bank account.
The fact also that in pharmacy one may fairly be said to be in
the scientific world, if not very far in, is also not without its
important aspect ; and in this connection I might say that
pharmacists as a body might secure to themselves a higher
recognition to their scientific attainments if they were to make use
more of the advances of science in the realms bordering on pharmacy
proper. Every chemist ought to be a practical photographer,
every chemist should be conversant with water and urine analysis
every chemist should be able to prepare and mount specimens foi
the microscope. The poison cupboard also should have his special
attention, and it should be a matter of duty with him to stir up
within his fellow pharmacists a profound respect for the law as it
relates to him, and in combination with each other seek, by giving
voice in the proper quarter, to have placed in that cupboard such
other articles capable of destroying human life as are at present
without. In this world, where the only true knowledge is that
gained by experience and experiment (and I here speak of, and
146
PHARMACEUTICAL JOURNAL.
[Feb. 20, 1897
include, every department of science), the pharmacist by virtue of
his knowledge has large obligations to fulfil. His responsibility is
heavy, and as a scientist, however humble, he should see to it that
he does his part in sweeping away the mass of ignorance and super¬
stition that abounds on every side.
CRYSTALLOGRAPHY.*
BY H. MARSTON MORGAN.
The word crystal, derived from the Greek krustallos and Jcruos,
meaning ice, was used by the ancients for crystallised silica or
quartz in allusion to the then accepted idea that this substance
was ice rendered permanently solid by the action of intense cold.
In A. d. 1672 Rome de Lisle published his ‘ Essay on Crystallo¬
graphy,’ but the honour of being regarded as the founder of the
science is given to the Abbe Rene- Just Hatiy. He was born at
St. Just in what is now called the department of Oise, and amongs
other works published his essay on the ‘ Structure of Crystals,’ in
1784, and also his ‘ Treatise on Mineralogy’ and his ‘ Treatise on
Crystallography,’ both in 1822, the year of his death.
It is historically interesting that the idea of a crystal being ice
permanently solid was accepted by Paracelsus, and was not criti¬
cised until the beginning of the seventeenth century.
The various mineral substances of which the crust of the earth
is composed have been recognised and classified according to their
crystalline forms. For a long time the external form was the most
essential, but now this idea has partially given way to the examina¬
tion of the regular internal structure.
If ordinary homogeneous substances be examined physically, they
are found to be equal in their hardness, elasticity, etc. , but crys¬
tals differ from this, and this is one of the fundamental principles
of crystallography. The distribution of physical properties is
equal along all parallel directions, while with certain exceptions it
is unequal along directions which are not parallel. A glass model
of a crystal may be made, but it is not a crystal, because it lacks
the necessary internal structure.
Matter is composed of a number of ultimate particles called
atoms, which are always in a state of intense vibration and
separated from each other by distances vastly greater than their
own diameter. The chemical molecule is taken as the unit of sub¬
stance, because we cannot imagine it to be divided without altera¬
tion, but we must take it that all crystal molecules in the same
crystalline substance must be identical in shape, size, and in the
distribution of forces ; for different substances they must be
naturally of different shape, while for the same substance under
different conditions they may or may not be different. The reasons
of crystals taking more than one geometrical form I will refer to
under the term of the “ habit of crystals.”
Many substances show physically that they do not possess any
regularity of molecular structure whatever ; such substances are
termed amorphous. Substances only known in the amorphous state
are usually of an indefinite chemical composition such as coal, amber,
etc. And under certain conditions usually crystalline bodies may
assume the amorphous form by accelerating their rate of solidifi¬
cation ; for example, many silicates, when fused and rapidly
cooled, form glass. The real difference existing between
amorphous and crystalline bodies is therefore internal and mole¬
cular. A fragment of quartz and a fragment of glass may appear
the same, but in the former the elasticity is equal in parallel
directions, and different in directions not parallel, molecular
arrangement in the one is regular, in the other quite irregular.
Certain chemical substances do not possess the power, or
perhaps it would be better to term it the crystallising force to a
sufficient extent to allow their form to be examined, for example
the turquoise. The molecular forces which tend to produce a
regular internal structure in matter as it slowly solidifies exert
themselves in varying degrees, both in different substances under
the same conditions, and in the same substances under different
conditions. Then again, certain metallic sulphides rarely possess
well-defined crystalline forms, those occurring in the massive
state in huge lumps which rarely show any trace of crystal planes,
while other substances always occur in beautifully distinct forms,
for instance, carbonate of calcium and quartz.
The Method of Growth.
Crystals, unlike living organisms, always grow by deposition
of matter externally, and the fresh deposit exactly covers the
* Paper read before the School of Pharmacy Students’ Association.
crystal already formed, shaping itself to the angles and planes, and'’
becoming as it were lost in appearance ; thus, no limit can be set
down for the size of a crystal as long as the material and favourable
conditions remain.
The most beautiful forms of crystals are found naturally
amongst minerals, the results of exceeding slow changes constantly
occurring within the earth. The ordinary methods of the forma¬
tion of crystals are well known to you all ; it is invariably found!
that crystals deposited from a cold dilute solution are finer im
geometrical value and of larger size than those from strong solutions.
Water is probably the most general menstruum, and from such a
solution of salts crystals are usually obtained. Fusion and slow
cooling may be employed in many cases, for instance, sulphur and
bismuth.
Crystals may be also formed by the sublimation and subsequent
condensation of the volatile particles upon a cooler surface. Iodine
and arsenic are well-known examples. That crystals owe their
form to a certain regularity of internal structure is shown by their
mode of formation and the examination of peculiarities attending
their fracture. The tendency of crystals to split in certain,
definite directions, called cleavage, is a certain indication of
regular structure, while the optical properties of many, and mode!
of expansion by heat point to the same conclusion. Every
crystallisable body invariably assumes one of its own characteristic-
forms, or some form directly derived from it, or related to it by some-
simple law, and these forms are classified under six systems.
The plane surfaces bounding a crystal are termed faces ; when,
two contiguous faces intersect, an angle is formed. The faces,,
edges, angles of a most perfect crystal have equal faces, edges, and.
angles opposite to them, and if the middle points of the opposite-
faces, edges, or angles be joined by straight lines, the point at-
which these lines intersect will be the centre of the crystal, and
the lines drawn through this point the axes.
The same substance may assume, under different sets of circum¬
stances as at high or low temperatures, two different crystalline-
forms, and then the substance is termed dimorphous. Sulphur
and carbon furnish examples. Another case is presented by
calcium carbonate in the two modifications calc spar and arrago-
nite, both chemically the same, but physically different. Another
example is presented by mercuric iodide, which has two distinct-
forms and also two distinct colours. The contrast, however, is-
not so marked as the modification existing between diamond and
graphite.
The Habit of Crystals.
The different forms of crystals are produced by the various
arrangements of the molecules of which the crystals are composed,,
and there are but few exceptions in which a crystal varies to any
large extent ; the crystallising medium has also to be considered.
A graphic illustration of the molecular structure, as well as the
habit of crystals, may be advantageously employed. If the!
physical molecules be represented, say, by round steel balls, it is
easily seen how by the same arrangement it is possible to produce
different forms.
To illustrate this by an experiment mentioned by Hr. Williams
and based upon the well-known figures of Haiiy : —
If we represent the physical bodies by shot, a square of such
bodies arranged in parallel rows may be taken as a starting point,
and then by piling others upon them as cannon balls are piled, a-
symmetrical four-sided pyramid is produced. If the shot be made
to cohere by dipping them in shellac, a similar pyramid may be
built up on the other side of the base, thus forming the regular
octahedron. Again, if successive horizontal and vertical layers be
taken away equally from each of the six solid angles of the octa¬
hedron, this form is seen to gradually develop into the cube, while
the interior structure remains unchanged. Finally, we may use
each of the six faces of the cube as the base for the erection of a.
quadratic pyramid, and thus the dodecahedron is formed, with a
structure like that which produced the other two figures. Such
models as these admirably illustrate how differences of habit may
result from the same molecular arrangement, as well as how the
lanes of one form may replace the edges or angles of another. We
ave only to conceive of the shot as too small to be visible, and
the surface produced by any layer becomes a crystal plane.
Most probably the presence of impurities in the solution from
which the crystal grows plays an important part in conditioning
the habit. For example, sodium chloride will crystallise in octa-
hedra instead of in cubes when crystallised from a solution con¬
taining hydrate of potassium ; alum and sulphate of magnesia are
also affected in a similar way. Again, it rarely occurs that the
Feb 20, 1897]
PHARMACEUTICAL JOURNAL.
147
concentration of the mother liquor is the same on all sides of the
crystal, hence it is not surprising that the crystal grows quicker
on the side with the greater density, and thus the regularity of
form is often completely disguised.
The System of Crystallography.
The systems of classification depend upon the length and
relative positions of the axes of the crystal. Those in which three
axes intersect at right angles are termed orthometric, and when
the angles caused by their intersection are oblique they are called
clinometric.
The Monometric, Regular, or Cubic System. — These crystals have
three equal axes placed at right angles to each other, and in this
class are included the forms the regular octahedron and the
rhombic dodecahedron. Very many substances, both simple and
compound, assume this form, the most important being diamond,
common salt, iodide of potassium, the alums, fluorspar, sulphides
of the metals, the garnet, etc.
The Dimetric, Quadratic, Tetragonal, or Prismatic Pyramidal Sys¬
tem. — These are symmetrical, about three axes at right angles to
each other. Of these, however, two only are of equal length, and
the third unequal. The most important forms are the right square
prism and the right square based octahedron. Examples may be
seen in native stannic oxide and ferrocyanide of potassium.
The Hexagonal System has four axes, three of which are equal,
lie in the same plane, and cut each other at an angle of 60°. The
fourth axis may be longer or shorter than the other three, it cuts
them at their common point of intersection at a right angle. Zinc,
zinc oxide, silica, camphor, etc. , are examples of this form.
The Rhombic System has three axes of unequal length placed at
right angles to each other. Chlorides of lead, barium, mercury
and copper, nitrates of ammonium, and many other substances
adopt this rhombic system.
The Monoclinic System has three axes of unequal length, one of
the axes stands at right angles to the plane of the other two,
which are inclined to one another at different angles in different
crystals. Sulphur, hydrated sodium chloride, etc., crystallise in
this manner.
The Triclinic System has three axes, no one of which makes a
right angle with either of the other two. Compai’atively few sub¬
stances crystallise according to this system, among the chief may
be mentioned copper, manganese, and iron sulphates containing
five molecules of water of crystallisation. Potassium and silver
dichromates, boric acid, and grape sugar.
I might add, in conclusion, that the angles of crystals are
measured by an instrument called a goniometer, and the method
adopted is by the reflection of light along the axes of a crystal and
measured by a revolving graduating plate. The instrument is
somewhat complicated, but a surface of l/100th part of an inch in
length, if perfect and brilliant, will be sufficiently large to be
accurately measured by the reflecting goniometer.
EIGHTH INTERNATIONAL PHARMACEUTICAL CONGRESS,
BRUSSELS, AUGUST 14 to 19, 1897.
Questions to be Discussed.
1. In the actual state of science, is it not advisable to enforce
in all drugs and medicines a normal quantity of active principles ?
2. Is it not necessary to unify the modes of analysis of medicine
and of their active principles ? If so, what are the best ways of
doing so ?
3. As a question of public safety, what are the best regulations
of the practice of pharmacy.
4. From a bacteriological point of view, what is the best system
of analysis of drinking water ? How far can the methods actually
known be relied upon ?
5. Has the chemist the right of preparing and selling organic
essences and the substances employed in organotherapy ? Which
are the best ways of assuring the chemist of the value of these
substances, and also of serums ?
6. Show the best ways of encouraging the manufacture of new
medicines. Is it possible in patents to amalgamate the protection
of private trade and public good? Would it not be preferable for
the chemist to sell them and the doctor to prescribe them under
names more appropriate to their composition ?
7. Prepare the plan of a programme of pharmaceutical studies.
METRIC MEASURES AND OUR OLD SYSTEM.*
BY FREDERICK TOMS.
( Concluded from, page 69.)
In regard to measures of capacity, as well as weights, these in
the French system are based on the metre and its derivatives ; and
with both there is a close approximation to the 11 : 10 ratio.
Nevertheless it would be futile to attempt to apply this ratio in
such instances, because our English weights and our measures of
capacity are not divisible by 11, although the land-measures are.
There are certain points of similarity, however, between the two
systems, which will be easy to recollect if half a kilogramme be
taken as the basis of our new pound, and half a dekalitre as the
basis of our new gallon.
The kilogramme is equal in weight to a litre of distilled water ;
and the new gallon of 5 litres would thus weigh 10 new pounds. So
this measure would assimilate with our old gallon, the weight of
which is 10 of our present pounds.
Having thus obtained our basis, the gallon could be divided into
4 quarts, or 8 pints, or 32 gills, and so on, in exactly the same
manner as our existing English measures ; and multiples of the new
measures could likewise be formed in similar fashion by taking
2 gallons as equal to 1 peck (which would be exactly the same as a
dekalitre) ; while 4 pecks would make 1 bushel, and so on, in like
manner as at present.
For the heavier weights, the French tonne, of 1000 kilogrammes,
would be very nearly the same as our present ton, and the new ton
would be divided into 20 hundredweights, each represented by 1Q0
of the new pounds, which could be called the “ cental ” if so pre¬
ferred. For the lighter weights, the half- kilogramme (which in
common French parlance is still called by the old name of livre>
from libra, a pound) would be our new pound, and be divided into
16 ounces, as at present. This ounce is almost exactly the same
weight as our present troy ounce, and the same as our avoirdupois
ounce used to be before the pound was reduced to 7000 grains. In
former times, avoirdupois, troy, and apothecaries’ ounce were alike,
the difference in the pound being merely in the number of ounces
and we should do well to revert to that arrangement.
If it be thought desirable to divide the ounce into grains, there
are two methods, either of which might be adopted, and each has
some advantages. The first is to divide the ounce into 480 grains
(like the present troy and apothecaries’ ounce), and follow the
present subdivisions into drams, pennyweights, etc., without any
fraction, bat the gramme would be equal to 15 36 grains. The other
method is to divide the ounce into 500 grains, in which event 16 of
these grains would be exactly equivalent to the French gramme ;
but then the drams would contain a fraction of a grain.
The new measures might readily be accepted in place of our old
measures, because the mode of applying them would be the same
as hitherto ; but endless confusion and heartburnings would be sure
to result from an attempt to compel the untaught population to use
tenths and hundredths of a kilogramme or dekalitre, instead of
following the ancient practice of dealing in pounds and ounces^
quarts and pints. Far better would it be to legalise and define the
new meaning of old and familiar words, which would certainly con¬
tinue to be used by the great mass of the people.
APPENDIX.
(Not read with the paper .)
Since the foregoing paper was written, there has been introduced
into the House of Commons, under the auspices of Mr. Ritchie and
* Paper read at the meeting of the British Association for the Advance¬
ment of Science, held at Liverpool in September, 1896.
148
PHARMACEUTICAL JOURNAL.
[Feb. 20, 1897
Mr. Balfour, “ A Bill to Legalise the Use of Weights and Measures
of the Metric System.” At the commencement of the paper brief
allusion is made to this fact, but it has not been found necessary to
alter the paper in other respects.
The new Bill does not appear to advance a general adoption of
the metric system much more than the Weights and Measures Act
which was passed eighteen years ago. Sect. 21 of the Statute of
1878 enacted that “ a contract or dealing shall not be invalid or
open to objection on the ground that the weights or measures
expressed or referred to therein are weights or measures of the
metric system ” ; and the Schedule to that Act gave a list of metric
equivalents to the Imperial weights, and vice versd. Much the
same is said and done in the proposed new measure ; and it may be
of service, for purposes of reference, to state the nature of the Bill,
and therefore the clauses are here printed in full : —
A Bill to Legalise the Use op Weights and Measubes
op the Metbic System.
Be it enacted by the Queen’s most Excellent Majesty, by and with
the advice and consent of the Lords Spiritual and Temporal, and
Commons, in this present Parliament assembled, and by the
authority of the same, as follows : —
1. Use of Metric Weights and Measures in Trade ; 41 and 42 Viet,
c, 49. — (1.) Notwithstanding anything in the Weights and
Measures Act, 1878, the use of a weight or measure of the metric
system in trade shall be lawful, and nothing in Section 19 of that
Act shall make void any contract, bargain, sale or dealing by reason
only of its being made or had according to weights or measures of
the metric system.
(2.) A person using or having in his possession a weight or measure
of the metric system shall not by reason thereof be liable to any
fine.
(3 ) For the Third Schedule to the Weights and Measures Act,
1878, shall be substituted the Schedule to this Act.
2. Verification of Copies of Metric Standards, — Section 38 of the
Weights and Measures Act, 1878, is hereby. repealed, and the Board
of Trade shall verify copies of metric standards in the same manner
as if they were copies of Board of Trade standards, and the provisions
of that Act relating to the verification of local standards shall apply
accordingly. ,
3. Local Metric Standards. — In Section 40 of the Weights and
Measures Act, 1878, the expression “ local standards of
weights and measures ” shall include local metric standards, and
the provisions of that Act relating to local standards shall apply
accordingly.
4. Short Title. — This Act may be cited as “The Weights and
Measures (Metric System) Act, 1896,” and may be cited with the
Weights and Measures Acts, 1878 to 1893.
Besides the above enacting clauses, there is a loDg Schedule
giving the equivalents of Metric and Imperial Weights and Measures
in two forms, viz., from Metric to Imperial, and from Imperial to
Metric. Of these a portion is hereafter quoted ; and an extra
column is added thereto for the purpose of showing what differences
would be effected in the English equivalents of French measures, if
our basis was slightly altered, so as to accord exactly with the
metric base.
The figures given in the Schedule differ a little from those which
have hitherto been published in scientific books, as well in the
1878 Act, and likewise on cards dated from the Board of Trade
Standards Office in October, 1890, and issued by the Queen’s
Printers. For example, the equivalents of the metre are thus
given : —
Length of Metre Inches. Feet. Yards.
In the Schedule of the Bill .... 39-37012 . .. 3-2S0S4333 .... 1-09361444
In the Board of Trade Card .... 39-37079 .... 3-28089917 .... 1-09363306
Sach differences, however, are immaterial as regards the method
suggested in the foregoing paper, because the proposed new
measures would be based upon a definite portion of the metre itself
(the new yard being exactly ten-elevenths of the metre), and, what¬
ever may be the comparative dimensions of our existing yard, the
new one suggested in its place would give the following propor¬
tions : —
Length of Metre Inches. Ftet. Yards.
In the Proposed New System . 39-6 . 3-3 . 1-1
Besides the differences mentioned above, there are a few discrep¬
ancies in the Bill, mostly arising from typographical errors, and
these have been corrected in the following quotations where
apparent. In condensing the Schedule, many of the multiples or
subdivisions are here omitted, especially where they are mainly
repetitions of the same figures with different positions of the decimal
point.
Measubes op Length and Abea.
The following are some of the most material equivalents in the
conversion of French measures into English : —
Linear Measures.
Metre . . . ■
Dekametre (10 metres). . . .
Hectometre (100 metres). .
Kilometre (1000 metres) ..
Myriametre (lO, 000 metres)
Equivalents stated in
the Government Bill.
39"37012 inches ....
3-2084338 feet ....
1-09361444 yards ,.
10-9361444 „
109-361444 „
1093-61444 „
0-62137 mile .
6 2137 miles . .
New Equivalents
suggested in this Paper.
39 -6 new inches.
3 3 ,, feet.
IT ,, yards.
11 yards, or 2 poles.
110 ,, J furloDg.
1100 ,, 5 furlongs.
0"6'25 mile.
6'25 miles.
Square Measure.
Sq. Metre . . . 1T959926 sq. yards’
Are (100 sq. metres) . 119-59926 ,, „
10 Ares (1000 sq. metres) .. 1195-9926 ,, ,,
Hectare (100 ares, or 10,000 ( 11959-926 „ „
sq. metres) ( 2-47106 acres
1-21 sq. yards.
121 sq. yds., or 4 sq poles.
40 sq. poles, or 1 rood.
400 ,, or 10 roods..
2 '5 acres.
As regards the conversion from English measures into French, it
will suffice to give the following examples : —
Linear Measure,
Inch .
Foot . . . . .
Yard . .
Pole (5J ya ds) .
Chain (22 yards) .
Furlong ( 0 chains or 220
yards) .
Mile (i760 yards) .
Square Measure.
Perch (301 sq. yards) ......
Bood (40 perches) .
Acre (4840 sq. yards) .. . . _
Square Miie (640 acres) ....
Equivalents stated in the
Government Bill.
25-39997222 millimetres
0-30479967 metres .. ..
0 914399 . .
5-02919 „
20 116778 „
201-16778 . .
1-60934224 kilometres..
25-29280 sq. metres ....
10 11712 ares .........
0-40468 hectare .
258 99824454 heotares
New Equivalents
suggested in this rapes;
25-2525 millimet es.
0-30303 metre.
0-90909 „
5 0 metres.
20
200 „
1-6 kilometres;
25 "0 sq. metres.
10 ares.
0 4 hectare, or 40 arese
256 hejiarec.
With regard to land measures, the following comparative table
may show the results with more precision : —
English Land Measures.
5} yards square, or 1 square perch = \
“301 square yards. /
11 yards square, or 4 square perches I
= 121 square yards. J
1 square cnain, or 484 square yards (
= jtjth of acre. )
1 rood = 40 square perches.
4840 square yards, or 1 acre.
10 roods, or 2J acres.
1 square furlong, or 10 acres.
1 square mile = 640 acres.
Measubes
French Land Mbasuues.
{5 metres square, or a quarter of ai3
are = 25 square metres.
10 mettes square, or 1 are = 100
square metres.
20 metres square, or 400 square
metres = 4 ares.
1000 square metres, or 10 ares.
4000 squale metres, or U'4 hectare.
10,000 ,, ,, or 1 hectare.
400 ares, or 4 hectares.
256 hectares.
Capacity.
In the French system, the nomenclature used for measures o§
cipacity is uniform, whether employed for liquids or for coin and
other dried goods ; but in England we often use different names for
measures of equal dimensions. Thus, a bushel is equal to light
Feb. 20, 1897]
PHARMACEUTICAL JOURNAL.
149
■gallons ; bnt we do not say a bushel of beer, wine, or water, though
■we say a bushel of wheat. The principal measures in the two
systems are as follows : —
Equivalents stated Proposed New
Measures of Capacity. in the Bill. Equivalents.
dot over the i ; and mistakes are likely to arise from the dot being
omitted or overlooked.
Countries that have Adopted the Metric System.
The countries in which the metric system has been introduced,
and the dates of introduction of most of them, are as follows : —
T/itre=l cubic decimetre. . <
Dekalitre (10 litres) .
Hectolitre (100)
Kilolitre (1000 litres) _
1 -75985 pints ....
0 879925 quart.. ..
2 '195-81 gallons ..
2 '74976 bushels ..
27'4976 „
1*6 pints, or 0'8 quart,
or 0'2 gallon.
2'0 gallons, or 1 peck.
2 '5 bushels, o- 29 galls.
25 '0 ,, or 200 galls.
The new gallon, of half a dekalitre, may be divided into 4 quarts^
or 5 litres, or 8 pints, or 10 “chopines”; but the 'ch opine ” does
not occur in the Bill, as it is not a recognised measu.e, although in
popular use in France as representing half a litre.
The following are the principal English measures of capacity and
-their present metric equivalents ; to which are appended the corre¬
sponding proportions, if our English base were modified as proposed
in the paper :
Mea-ui cs of Carac’ty
Pint (4 gills) .
•Quart (i pints) .
Gallon (4 quarts) .
Peck (2 gallons) .
-Bushel (4 pecks) .
Present Equivalents.
0-55823 lities .
1-13646 „ .
4-5458547 . .
9 09171 „ .
3-63668 dekalitres .
Proposed Equivalents.
0-625 litres.
1-25 „
5
10 litres, or 1 dekalitre.
4 dekalitres.
Conversion of Metric into English Weights.
The weights are proposed to be derived exactly from the
anetric base. Let the kilogramme be divided into 32 ounces.
6 of which should constitute the new metric pound ; and the
new ounce would then be almost identical with the existing troy
ounce. The generality of the population would not require smaller
divisions than the half and quarters of an ounce ; but, if further
subdivision should be considered desirable, there are two alternative
methods, each of which possesses some slight advantage over the
other. One method is to divide the ounce into 480 grains (similar
to the present troy ounce) when all subdivisions could remain as at
pr esent, and would run as follows : —
15360 grains = one kilogramme.
7680 „ = half kilogramme, or new pound.
480 ,, = oDe ounce, bting the 16th p?rt of the avoirdupois pound, or
12 th part of troy or apothecaries’ pound.
.240 ,, = half an ounce — same number as pennies in a monetary pound
or pennyweights in a troy pound.
■60 „ = apothecaries’ drachm, of 3 scruples.
30 ,, = avoirdupois dram, 16 to the ounce.
24 ,, = pennyweight (20th part of troy ounce) ; originated at a time
when an ounce of silver was worth 20 pence.
20 ,, = scruple (24th part of apothecaries’ ounce).
Of course, tenths of the kilogramme, or fifths of the pound, could
•also be used if thought desirable.
In the second method, the ounce might be divided into 500
grains, in which case there would be subdivisions of the half and
-quarters, as well as fifths and tenths of an ounce ; while 16 grains
would be exactly equal to 1 gramme, and conversions from one to
the other would accordingly be very easily made. In such case
there would be the following similarities of number in the divi¬
sions : —
16 grains = 1 gramme,
16 drams = 1 ounce.
16 ounces = 1 pound.
500 grains = 1 ounce.
301 gTalns = 1 dram.
30| grammes = 1 ounce.
16,000 grains = 1 kilogramme.
500 grammes = 1 pound.
Why the avoirdupois “ dram ” is spelt without the ch, and the
apothecaries’ “ drachm ” with those letters, I am unable to say ; but
they are thus spelt in the Bill and in the Board of Trade cards, and
they have the advantage of distinguishing the one from the other.
In both Bill and card, the French word “ gramme ” is contracted to
-“gram.” This is advantageous in one respect, especially as shorten¬
ing the word in kilogram, centigram, etc. ; but if “ gram ” is used
alone there is a liability to error in writing and printing, as the
-only difference (when written) between “ gram ” and “ grain ” is the
Argentine Republic (1887).
Mexico (1884).
Austria-Hungary (1876).
Netherlands (1820).
Belgium.
Norway (1878).
Brazil (1862).
Peru (1860).
Bulgaria.
Portugal.
Chile.
Roumania (1876).
Colombia (1857).
San Domingo.
Costa Rica.
Servia (1875).
Denmark.
Spain (1859).
Ecuador (1857).
Sweden (1879).
France.
Switzerland (1873).
Germany (1872).
Turkey (1882).
Greece (1832).
United States (1866).
Hayti.
Uruguay (1864).
India (Bengal), 1871.
Venezuela (1857).
Italy.
In many of these countries the metric system is compulsory ; In
others, as in the United States, its use is authorised though not
compulsory ; and in some instances other systems are also in vogue,
especially in South America, where the old Spanish weights and
measures are still employed. Even in France itself there is the
“ systeme usuel,” or old style of nomenclature, in which the
measures are stated in pouces or inches, pieds or feet, livres or
pounds, and so on ; but instead of the foot being divided into twelve
inches, as formerly, the new arrangement had but ten divisions, and
the transition was consequently rendered very difficult.
A Postscript.
It possibly may save some trouble to students of this subject if
two other methods for converting metres into yards are briefly
alluded to. To those who compare the metric and English systems,
the first method readily suggests itself, and is likely to mislead
persons who only look at it superficially. Thus, if the metre were
divided into 40 inches, in such case the length of the yard would
be equal to nine-tenths of a metre, or 9 decimetres ; the foot would
be 3 decimetres ; 4 inches would be a decimetre, and the inch would
be exactly a quarter of a decimetre.
This seems remarkably simple at the first glance, owing
to the absence of decimal fractions ; but the simplicity is
fallacious, and the absence of fractions ceases with the inches
The conversion of metres into furlongs, miles, acres, etc.,
would be productive of an interminable repetition of decimals.
Thus, 100 metres would be equivalent to 111-111, etc., yards,
and 1600 metres, instead of being an exict mile, would be
1777-777, etc., yards ; while the square measures would be still worse.
In short, by the 11 lOths process, described in the foregoing paper,
the metre would be equal to a yard and one-tenth ; by the 10-9ths
process, here alluded to, the metre would be equivalent to a yard
and one-ninth, and would prove practically unmanageable.
A much preferable plan would be to divide the metre into 36
parts, and apply our present names thereto. The principal dis¬
advantage would be that the small measurements, which are more
in use than any other ( [i.e ., the inches, feet, and yards), would all be
considerably longer than they now are, as each of them would be
increased by about one-tenth. But larger measures would fall in
well with the metric code, as the yards being exactly equivalent to
metres, their number, in comparison with poles, furlongs and miles,
chains, roods, acres, etc., would be the same as are given in metres
in the column of “ new equivalents ” stated in the table on page 148.
150
PHARMACEUTICAL JOURNAL.
[Feb 20. 1897.
THE STUDEHTS’ PAGE.
ON DISPENSING EMULSIONS.
It may be be assumed that, following the directions given on
page 130, the student has overcome the preliminary difficulties
that attend the production of a satisfactory emulsion of fixed oil with
acacia, and he should now proceed to emulsify other drugs with
the same emulsifier. Balsam of copaiba is a suitable one to ex¬
periment with. It can be emulsified by either of the methods
given for fixed oils, but the second, in which the acacia is first
converted into mucilage, is to be preferred, especially if the balsam
is rather viscid. The directions given in the previous article
should be followed, and should result in the production of a milk-
white emulsion. Liquid extract of male fern can similarly be
emulsified with mucilage of acacia, but if the quantity of water
ordered is comparatively large it is well to use half a drachm of
acacia (gum) for each drachm of liquid extract. Balsam of Peru
makes an excellent emulsion when treated in the same way ;
in this case one-fourth of its weight of acacia is sufficient
In point of fact, as the student by this time will have gathered,
fixed oils, oleo-resins, and balsams can, generally speaking, be
emulsified with one-fourth their weight of acacia ; the first-named
by either the dry gum or the mucilage method, the last two pre¬
ferably by the mucilage method.
Volatile oils are not quite so amenable as fixed oils ; they require
rather more careful treatment. Oil of turpentine affords a very
good example ; it can be emulsified with one-fourth of its weight
of acacia, which, in this case, must first be converted into muci¬
lage. Weigh two drachms of acacia, and convert it into a smooth
mucilage in the mortar with half an ounce of water. Measure one
fluid ounce of oil of turpentine, and add a few drops to the muci¬
lage. Triturate until emulsified ; then add a few more drops, and
triturate again. It may now be added in quantities of about
twenty to thirty minims, being careful to emulsify each portion
before another is added. From time to time, as the emulsion
thickens, a few drops of water should be added. Should the
mixture in the mortar assume the appearance of large globules of
emulsified turpentine, separated by thin films of turpentine that
refuse to emulsify, as it will after the addition of about four or
five drachms of turpentine, the addition of water is indicated, and
a small quantity will usually restore the emulsion. After the
emulsion has been effected the dilution with water must be care¬
fully proceeded with ; at first small quantities should be added,
but as the emulsion is thinned it may be diluted more boldly.
All volatile oils may be emulsified in this way, but if the propor¬
tion of oil to water in the mixture is large use a larger proportion
of acacia, say twice as much, i e. , half the weight of the oil taken,
as directed for liquid extract of male fern.
Hydrocarbon oils, such as adepsine oil, may be treated in the
same way. Solid paraffins, such as vaseline, also yield satisfactory
emulsions with acacia, though they give a little trouble. The
student should try the following one : — Put half an ounce of vaseline
into a dry mortar, add two drachms of finely powdered acacia,
and mix. Now add at once four drachms of water, and triturate
until the mixture first assumes a granular condition, and finally
becomes perfectly smooth, after which the addition of water may
be proceeded with ; or the water may be added to the mixed vaseline
and acacia in successive small quantities, in which case, however,
more trituration is necessary. From this emulsion, as from others,
a cream will separate on standing, especially if much water has
been added, but this cream can be diffused through the water by
agitation. Vaseline can also be emulsified by adding it gradually
to the mucilage, previously prepared, but in this case it will
separate more readily.
Acacia may also be employed for the emulsification of solid
animal fats and waxes. These should be melted and poured into
a previously heated mortar ; the powdered acacia should then be
incorporated, and the emulsion made with boiling water. Let the
student try the following emulsion : — Melt half an ounce of yellow
wax in a small porcelain capsule, and pour it into a mortar, which,
with its pestle, has been previously heated with boiling water.
Incorporate half an ounce of finely-powdered acacia, and add at
once one ounce of boiling water. Triturate until the emulsion is
formed, and when the mixture has cooled proceed to dilute it
with water.
The student will now have acquired some proficiency in the use
of acacia as an emulsifier. He must not, however, imagine that
this is the only agent that may be or should be used to produce an
emulsion, and it is proposed in a succeeding note to deal with
emulsions prepared with other emulsifiers than acacia.
NOTES ON THE B.P.
Aqua Destillata.— Note the directions to reject the first portion,
which would contain nearly all the ammonia and some of the
carbon dioxide present in spring water. The reason for discon¬
tinuing the collection before the whole of the water has been dis¬
tilled may be easily demonstrated by evaporating some water to
dryness in a dish and gently heating the saline residue. This
darkens, owing to the charring of organic matter, and gives off
unpleasant odours. The starch and potassium iodide test is to
detect nitro?<s acid. This liberates iodine if present in very minute
quantities, the nitrous acid being reduced to nitric oxide. The
formation of more than a faint yellow coloration with Nessler’s
reagent (alkaline potassio-mercuric iodide) would indicate the
presence of an undesirable quantity of ammonia.
Aqua Laurocerasi. — The proportion of HCN, *1 (l/10th)per cent,
in the standardised product should be carefully remembered. It
is, therefore, l/20th the strength of acidum hydrocyanicum
dilutum. The body amygdalin, which yields the hydrocyanic acid,
is a typical member of the class of substances known as glucosides.
Argenti Nitras. — Solution of nitrate of silver and hydrochloric
acid form silver chloride and nitric acid,
AgN 03 + HC1 = AgCl + HNO,.
The filtrate, therefore, leaves no residue when evaporated. This
distinguishes pure nitrate from “toughened caustic,” which
leaves a white residue of potassium salt after similar treatment.
Argenti Oxidum. — Moist silver oxide absorbs carbon dioxide,
forming carbonate. It is, therefore, desirable to wash and dry the
precipitate as quickly as possible. Potassium and sodium hydrate
precipitate silver oxide from solution of the nitrate, as well as
calcium hydrate, but the excess of calcium salt is said to be more
quickly removed by washing. Silver hydrate (which might be
expected to be produced) is not stable, but decomposes into oxide
and water —
2AgN 03 + Ca2( HO ) = Ca2(N03) + Ag20 + H20.
Oxide of silver is easily reduced to metallic silver by heat or
contact with organic matter. Absence of effervescence when
dissolved in nitric acid shows absence of metallic silver or
carbonate.
Arsenii Iodidum. — Note the inconsistency in the official dosage
of this. The liquor arsenii et hyd. iodid. contains ‘ ‘ about 1 grain
in 100,” and may be (and actually is) given in doses up to 30
minims. This quantity would contain nearly | grain of Asl3,
although the official dose is l/30th grain. The latter is undoubtedly
wrong. AsI3 is a very weak compound, decomposed by boiling
with water into hydriodic and arsenious acids. The halogen com¬
pounds of phosphorus are decomposed in an analagous manner by
mere contact with water, PBr» yielding hydrobromic and phos¬
phorous acids 1
PBr3 + 3H-OH = 3HBr + P(OH)3.
Beberince Sulphas. — This was introduced as a febrifuge, but the
low price of quinine has left very little room for its use. The
absence of ash when ignited in air distinguishes it at once from the
red iron scale preparations. Note the disagreeable fishy odour
given off during ignition.
Bismuthum. — Bismuth, like antimony, does not form normal
salts soluble in neutral aqueous solution. Unless considerable ex¬
cess of acid be present an insoluble oxysalt is produced. For
medicinal use the insoluble oxy nitrate and oxycarbonate are given
either as powder, pill, or suspended in aqueous vehicles. The
large quantity of acid necessary to dissolve these oxysalts to
normal salts rendered it impossible to give bismuth in solution
until its property of forming soluble double compounds with
alkali salts of organic acids was discovered. Citrate of bismuth
and ammonium is one of these compounds : it affords the physician
the means of giving bismuth in neutral or alkaline aqueous
solution.
PHARMACEUTICAL journal,
151
' Feb. 20, 1897]
Pharmaceutical Journal.
A Weekly Record of Pharmacy and Allied Sciences.
ESTABLISHED 1841.
Circulating in the United Kingdom, Prance, Germany,
Austria, Italy, Russia, Switzerland, Canada, the
United States, South America, India,
Australasia, South Africa, etc.
Editorial Office : 17, BLOOMSBURY SQUARE, W.C.
Publishing and Advertising Office : 5, SERLE STREET, W.C.
LONDON : SATURDAY, FEBRUARY 20, 1897.
THE INNER STRUCTURE OF MATTER.
As far back as 1863, Otto Graham suggested that the
solid, liquid, and gaseous conditions of matter probably
always exist in every liquid or solid substance, one pre¬
dominating over the others, and the results of researches
conducted by Professor W. Spring ( Bulletin de VAcademie
de Belgique) and by Professor W. C. Roberts-Austen,
Chemist and Assayer to the Mint, have fully confirmed that
hypothesis, demonstrating the continuity of the three states
of matter, and explaining why that continuity exists. Gases,
as is well known, are conceived as consisting of molecules
continually moving in all directions, the velocity of this
movement being increased by raising the temperature.
Liquids are also assumed to be composed of molecules
which are capable of moving about freely, though less rapidly
than in the case of gases. At the “critical point ” where
matter passes from the caseous to the liquid state, or the re¬
verse, it combines the properties of the gas with those of the
liquid, and it has lately been proved, Prince Kropotkin points
out in the Nineteenth Century , that mechanical laws which
hold good for gases are as fully applicable to liquid solutions,
as if they really contained gaseous molecules. Apparently
there is no substantial difference between #the inner structure
of a gas and that of a liquid, what difference there is being
one of degree only, in the relative freedom, mobility, and
speed of molecules, and perhaps in the size of the particles.
But even in seemingly inert masses of metal and other
solid bodies the molecules are not devoid of motion, and
metallurgical experiments prove conclusively that these
minute particles of matter never cease to move about, chang¬
ing place indefinitely and entering into new and varied
combinations. The study of alloys has afforded the
necessary evidence required to convert a supposition into
certainty. Alloys, of course, are compound metals, and they
combine the characteristics of merely physical mixtures and
chemical compounds. They are totally different in their
properties from the component metals, usually vann¬
ing in colour, hardness, resistance to electric currents, and
melting point. Thus, when tin, lead, and bismuth are mixed
rapidly with mercury, after being as finely divided as possible,
the temperature is reduced to 14° F., a freezing mixture
being thus produced. A mixture of bismuth, lead, tin, and
cadmium fuses in boiling water, though tin alone, the most
readily fusible of the four metals, does not melt below
446°. The addition of a minute trace of tellurium to
bismuth so changes its aspect that it might be taken for a
totally distinct elementary body. Similarly, gold is coloured
purple by the addition of aluminium and green by the ad¬
dition of zirconium, whilst the presence of thallium causes it
to lose half its strength, and a trace of silicon causes it to
soften in the flame of a candle. Bismuth in copper destroys
its electric conductivity, and iron can be obtained in all sorts
of conditions, from the pure metal, soft as copper, to chrome
steel shells which will pierce nine-inch armour plates, backed
by eight feet of solid oak, without their points being de¬
formed. “ A block of an alloy is thus quite a wo Id, almost
as complicated as an organic cell.” Moreover, a close resem¬
blance has been shown to exist between molten alloys
and solutions of salts in water and other solvents, the same
complicated physical and chemical phenomena being pro¬
duced by dissolving one metal in another, or by mixing two
molten metals, as when a salt is dissolved in water or the
latter mixed with alcohol. The physical properties of the
metal used as a solvent, observes Kropotkin, are entirely
altered as the molecules of the dissolved metal travel, as if
they were in a gaseous state, amidst its own molecules.
“ Some of them are dissociated at the same time, and new
chemical compounds of an unstable nature are formed, only
to be destroyed and reconstituted again. In a word,
all laws based on the assumption of a nearly gaseous
mobility of molecules and atoms, which have been found to
be applicable to solutions of salts in water, can be fully
applied to molten alloys as well.”
But the question remained whether the mobility of the
molecules disappears or not when an alloy is solidified, and
to this the answer is supplied by Spring’s experiments. He
has been able to weld small cylinders of steel, aluminium,
bismuth, cadmium, copper, tin, lead, gold, and platinum, by
simply pressing them together by means of a hand-vice, after
their ends had been carefully planed true to l/2500th of an
inch. Whether the cylinders consisted of the same or differ¬
ent metals, they were invariably found to be solidly welded
to each other, after remaining under pressure for a few
hours. If at the same time they were heated to a tempera^
ture very remote from their fusion temperature, all traces of
the joint disappeared, and when the united cylinders were
subsequently torn asunder by means of a porverful machine,
quite new tearing surfaces were produced. Real alloys can
thus be formed by simple contact, interpenetration of the
molecules of the two component metals taking place, though
both remain perfectly solid meanwhile, and “ the great
puzzle of plasticity in the most solid rocks and the most
brittle metals thus ceases to be a puzzle.” Alloys have also
been prepared by pressing together fine filings of different
metals and, finally, Spring has proved that metals in the solid
state evaporate from their surfaces, just as camphor evaporates.
It was previously known that rods of lead, steel, or glass will
become permanently bent if left resting on their two ends
only for a considerable time ; and that solid lead, copper, or
steel under pressure will “ flow ” through an opening, exactly
in the same way as clay, which reproduces the flow of a vein of
water thiough the same opening. Adding to these facts
152
PHARMACEUTICAL journal.
[Feb. 20. 1897
the phenomena observed by Professor Spring— which show
that the superficial molecules of a solid piece of metal enjoy
the same mobility as if that surface were in the liquid state,
.and can as easily be freed from cohesion with their neigh¬
bours and projected into space, as if they were gaseous mole¬
cules — Graham’s broad generalisation of thirty-four years ago
is clearly verified, and enables the required explanation of
these recently noted phenomena to be furnished. A decisive
proof of the hypothesis, which has been practically lost
sight of for many years, was furnished by Professor
Roberts-Austen, who# was at one time a co-worker with
Graham, when he announced in a lecture before the Royal
Society twelve months ago that gold can diffuse through
lead cylinders, and as Kropotkin pertinently points out, it
would now appear that metals “probably are never quiescent,
-and fully deserve that the methods so fruitful for the study
<of living beings should be applied to them and their alloys.”
A THEORY OF VEGETABLE ANTITOXINS.
At a meeting of the Asiatic Society of Bengal, held at
'Calcutta on January 6, a “Theory of Vegetable Antitoxins ”
was presented by Surgeon-Captain H. A. Cummins, I M.S.
who believes that an analogous process may take place
'■naturally in plants to that which results in the formation of
antitoxins in animals. So far as he knows, no satisfactory
explanation has yet been given as to the origin or use in the
plant of the majority of substances, chiefly of a toxic nature,
•produced as the result of the secondary products of metas¬
tasis. That these poisons are lethal to the organisms in the
soil, and primarily produced by their irritation of the plant
by entering it and causing fermentation, seems to him a
simple explanation. He points out how colouring matters
may gain admission to the plants’ vascular system, also
dhat the cells exercise an absorptive or destructive
•Influence in the case of the colouring matter absorbed
by hyacinths. Moreover, he dwells upon the symbiosis
which takes place between certain fungi and the roots of
green-leaved plants, and suggests that from analogy we may
• conclude that there may be a similar relation between bacteria
and the roots favourable or otherwise to the plants concerned.
There is also the possibility of entrance by the stomata. If
•the protoplasm is seen, in the fermentative processes of
metastasis in planfs and animals, to act similarly in each case,
it may be inferred that under favourable conditions antitoxins
maybe formed in plants as in animals by any matter capable
• of stimulating the cells in the required manner. From a
consideration of these and many other circumstances, it
-seems to Dr. Cummins almost certain that organisms do gain
admission to the vascular systems of plants. The irritation
which they produce on . the cells probably leads to the
formation of antitoxins, and amongst these antitoxins may
be included many of the alkaloids and other plant
principles which are constantly employed as medicinal
'•remedies, and for other purposes. These may exist in
7the plant in the form in which we know them, or in
.-such a state that a very slight change by the action of a
ferment is capable of converting them into substances
capable of protecting the cells or into their known condition.
Further, it is urged, from what is known of the peculiarities
of protoplasm in different species, it seems quite possible for
one kind of protnphyte to produce toxins having different
•characters in different plants.
ANNOTATIONS
The Special Issue of the Journal, next week, will be sent to
everyone whose name appears on the Register of Chemists and
Druggists, the circulation of the number closely approaching
seventeen thousand. A unique opportunity will thus be afforded
for addressing the whole body of the craft in Great Britain, and
those who may be desirous of taking advantage of that opportunity
are requested to communicate with the Editor or Publishers with¬
out delay, so as to allow as much time as possible to make the
necessary arrangements. It is hoped on this occasion to produce
a record number of the Journal, both from a trade and a professional
point of view, and to this end readers are requested to co-operate.
The Eighth International Pharmaceutical Congress will dis¬
cuss the questions, a list of which appears at p. 147, during the six
days, August 14 to 19 inclusive. Anyone interested in pharmacy will
be entitled to become a member and participate in the proceedings,
on payment of a subscription of ten francs. Individuals or asso¬
ciations contributing towards the expenses of the Congress will be
entitled to election as honorary members, and will receive all
papers published in connection with the Congress. The French
language will be employed as far as possible, and sections will be
formed to deal with matters that cannot well be considered by the
Congress as a whole. Three prizes are offered for papers on
scientific and practical questions of pharmaceutical interest, and
three more for papers on professional interests. A list of twenty
suitable topics for papers will be sent on application to the General
Secretary, M. Maurice Duyk, 102, Chaussee de Wavre, Brussels,
who will also be glad to furnish any other information that may
be desired respecting the arrangements for the Congress.
The School of Pharmacy Dinner will be held at the Holborn
Restaurant on Friday next, at 7 p.m., Professor Greenish in the
chair. There is already every prospect of a most successful
reunion of past and present “ Square ” students, but this final
notice is published in the hope that many others who have as yet
neglected to secure tickets will hasten to communicate with the
Honorary Secretary — Mr. T. P. Tebbutt, 17, Bloomsbury Square,
W.C. — who will be glad to find room for more.
Penny in the Slot Electricity is the latest mechanical
development, according to the Daily Telegraph, a London company
having undertaken to supply electricity for an eight-candle power
incandescent lamp, during six hours, to any consumer prepared to
drop the most popular coin of the realm into a specially devised
machine. The light can be turned on or off as desired, and some
of the machines are so made that thirty-six pennies can be dropped
in at the same time, and the meter will then continue to work until
full value in electricity has been rendered. In the case of gas similar
arrangements have proved very successful in London, leading to
the use of that illuminating agent in many cases where it would
not otherwise have been employed. If, therefore, electricity can
be supplied on similar lines, its use in small houses may be expected
to increase rapidly.
The Manna of the Israelites has been supposed to be the
sap of a tamarisk ( Tamarix gattica-mannifera), exuded under the
influence of a parasite, but more recently it has been stated by
Kerner that an edible lichen (Lecanora esculenta, Pall. ) should be
regarded as the true manna. Writing in Science Gossip, M. J.
Teesdale refers to this statement, and after giving an illustrated
description of the lichen and several allied species, concludes by
observing that it is much more probable that the actual food of the
Feb. 20, 1897]
PHARMACEUTICAL JOURNAL.
153
Israelites consisted of the exudation still known as manna than
of the dry and insipid lichen. Edible lichens have been used
as food, when no other food was to be obtained, in Asia
Minor, Algiers, and elsewhere. When ground into flour, bread
has been prepared from them, which was pronounced little
inferior to wheat bread, but another account of the same
manna was to the effect that it was hard, inodorous, and
insipid. French soldiers have used edible lichens as provender for
their horses in the Sahara, and this curious natural product has
doubtless served as food for both men and animals in several
countries. Sweet gummy mannas are yielded by various species
of Alhagi, as well as by the tamarisk, the exudation in the latter
case being consequent upon punctures by the Coccus manniparus,
Ehr. It is doubtful if the evidence offered by the author will
carry conviction either one way or the other, but the paper
is useful for the information given concerning several of these
gummy exudations known under the term “ manna.”
The Chemists’ Exhibition is to be held this year in Covent Garden
Theatre, London, the space required being greatly in excess of
that occupied in former years. The exhibition will remain open
during five days, August 16 to 20 inclusive, and will thus follow
closely on the Conference at Glasgow. The arrangements are
much the same as last year, only on a much more extensive scale,
and full particulars may be obtained of the Manager, 42, Bishops-
gate Without, London, E.C.
The Chemistry of Tea was the subject of an exhaustive lecture
before the Society of Arts on Wednesday, February 10, the lecturer
being Mr. David Crole, who has had practical experience of the sub¬
ject, both as a chemist and as a planter in Assam. The object of
the lecture, a full report of which appears in the Society’s Journal
for February 12, is apparently an attempt to secure the improve¬
ment of the fragrant leaf by inducing manufacturers to resort
less to rule-of-thumb methods. A better knowledge of chemistry
seems to be required in this industry as in so many others.
The Nansen-Sverdrup Expedition records are partially dis¬
closed to the public this week, but the complete results of the ex¬
pedition from a scientific point of view will not be published for
some time to come. Already, however, we know that the formerly
mysterious ice realm of the North Polar area is to a very great ex¬
tent brought within the limits of positive knowledge. The Arctic
basin is now known to be a broad, pear-shaped gulf, 2500 miles
long, and 900 miles broad at its entrance between Greenland and
Norway, widening to 2000 miles at its nearly blind Behring Strait
end. Prince Kropotkin, in the current issue cf the Nineteenth
Century, gives a clear account of the oceanic currents in this
gulf, and shows that the polar basin is a real continuation
of the deep trough of the North Atlantic, its water being in as
regular circulation as that of other oceans, and heat and cold as
regularly exchanged there as in the Atlantic or Pacific. The
warm current from the Atlantic is still felt under the 85th degree
of latitude, but it is found underneath the cold current, its greater
salinity rendering it the denser of the two, although it retains
there a temperature of about one degree Fahrenheit above freezing
point. The result is that the Arctic Ocean is prevented from
freezing in its depths and becoming a terrible reservoir of cold.
The Drug and Chemical Trade of Japan, according to the
Board of Trade Journal, which quotes from the Japan Weekly
Mail, has advanced in proportion to the progress in other lines of
industry. Pills, ointment, powders, and similar preparations, in
addition to the so-called kaden myoyaku (patent drags ranged under
the title of hereditary family secrets), included only 140 varieties
twenty years old, but since the stamp duty was enforced in 1886,
a considerable change has come about in the drug trade. The
“ hereditary family secret drugs” have been gradually superseded,
and drugs compounded after the foreign style have appeared in
large numbers. “ Quinine bitters ” is described as having enjoyed
a remarkable popularity for about two years, and at present every
druggist of note has among his list of drugs one or more com¬
pounded with quinine bitters “for restoring the disorders of the
digestive organs.” Indeed, drugs of this description are now said
to be very numerous, there being at least forty varieties, and even
“ hair restorer” has run to five or six varieties in Japan.
The Foreign Trade of the United Kingdom for the month
ending January 31 last shows an increase in imports over the corre¬
sponding period in 1896, and a decrease in exports, both of British
and Irish produce and manufactures, and of foreign and colonial
merchandise. The following are the figures : —
1897.
1896.
Increase
Decrease
Per cent..
Imports .
£
39,975,668
£
38,473,856
11,146,491
4,806,3S4
£
1,501,812
£
3*9
Exports (Home Produce, etc.) . .
Exports (Foreign and Colonial)
19,762,378
4,177,82.
1,384,11!
628,55!
6-5
13-1
Alarmist critics will probably contend that these figures all indi¬
cate a retrograde tendency, whilst optimists will point with
satisfaction to the fact that we are receiving more goods in
exchange for a smaller output, and the statistics will doubtless be
so manipulated as to present what is apparently a clear case on
both sides. But after all there does seem to be something in the
argument that increasing imports and decreasing exports may
alike betoken extra prosperity amongst the people at large, who,
though doing less work, receive better pay and have more to
spend on imported luxuries.
Our Trade with British Possessions is greatly improved from,
the protectionist point of view, the value of exports from the
United Kingdom having risen from £70,001,524 in 1895 to
£83,934,874 in 1896, whilst the imports show a decrease from
£95,530,210 in 1895 to £93,323,263 in 1896. That is to say, our ex¬
ports to British Possessions show an increase for the past year of
£13,933,350, and our imports from there a decrease of £2,206,947.
The United States and most other American countries sent us more
goods than formerly in 1896, and the same was the case with France,
Belgium, Roumania, Germany, and other European countries, ex¬
cept Russia, Turkey, and Greece, which sent less during 1896 than,
the previous year. On the other hand, exports to Germany, France,
and all other European countries, except Spain, Italy, Austria,
and Turkey, increased last year. Readers interested in these facts
will find details in the Board of Trade J ournal for F ebruary.
Medicated Pencils are described by Mazurier (Bull. Commer.,
xxv., 33), which appear to be crayons composed of salts con¬
taining water of crystallisation. They are prepared by crushing
the crystals to coarse powder, spreading this out on an iron or
copper plate, and heating it until dehydrated. The masses are then
reduced to fine powder, and water is added drop by drop, the
mixture being massed until of a pilular consistence. The mass is
quickly rolled out to the prescribed length on a marble slab, and
allowed to dry in the air. In half an hour the pencils will be found
to be dry and hard, and indistinguishable from those cast in a
mould. Crayons of alum, copper or iron sulphate, and silver
nitrate may readily be prepared in this manner.
154
PHARMACEUTICAL JOURNAL.
| Feb 20 1897
PARLIAMENTARY NOTES AND NEWS-
Return Tickets. — Mr. Macdona, the Conservative member for
the Rotherhithe Division of Southwark, and whose name will be
familiar to chemists on account of his attempt some two years ago
to draw Parliamentary attention to carbolic acid poisoning, has
identified himself with another useful movement by introducing a
Bill to make railway return tickets available during the year of
their issue. It is to be hoped this tilt against the railway com¬
panies may be mors successful than the honourable gentleman’s
almost-forgotten effort to move the Privy Council in the direction
of scheduling carbolic acid as a poison within the meaning of the
Pharmacy Act, 1868, but it is doubtful, seeing that the second
reading is not till J une 2.
Vaccination, as was hinted some time back in these pages,
is going to furnish plenty of work to Ministers during
question time. Mr. Logan and his colleagues in the House,
who champion the right of parents to a free choice in the
question of the inoculation of their children, are still plying
the President of the Local Government Board with interroga¬
tions as to when the recommendations of the ., Royal Commis¬
sion are likely to be put into practice. The latest querist is
General Ruksell (Cheltenham). In reply to that gentleman last
week, Mr. Chaplin gave a very plausible reason for delaying
amendment of the Vaccination Acts. He pointed out that among
the various things recommended by the Commission was the further
investigation into the effects of storing vaccine in glycerin— a
method which Dr. Copeman, one of the Board’s inspectors, had
found, by experiment, to be worthy of consideration. Acting upon
this recommendation, Dr. Thorne Thorne and Dr. Copeman had
been sent to Paris, Brussels, Berlin, Dresden, and Cologne to elicit
information as to the preparation, storage, and distribution of
glycerinised calf lymph, as well as the results attending its use.
Naturally some time must elapse before the information obtained
can be collated and presented as a report, but Mr. Chaplin further
showed the improbability of legislation on Vaccination this year
by reminding the House that any important change in the lymph
supply must necessarily bring about a very considerable modifica¬
tion in the system of public vaccination.
Registration of Firms. — This Bill, which is designed to dis¬
close “who’s who” in commercial associations, was brought in by
Sir Stafford Northcote, and Sir J. Leng on the 5th instant, and
will appear on the paper for second reading on March 17. The
registration is proposed to be effected under Board of Trade rules
by the Registrar of Joint Stock Companies, and the statements
registered would be available for public inspection on payment of
a small fee. Such a measure would be a very valuable adjunct to
an amended Companies Act.
The Midwives Registration Bill, now awaiting second reading,
though not exactly pharmaceutical, will be of interest to chemists,
and a brief description of its provisions may not be out of place.
The object of the Bill is to enable the public to distinguish between
competent and incompetent midwives, and the promoters seem
sanguine that the discerning public will naturally choose the com¬
petent practitioner. Be this as it may, the Bill proposes
to call into existence a midwives board to be constituted
by the General Medical Council, and to consist of three
nominees each, of the Royal College of Physicians, Royal
College of Surgeons, the Society of Apothecaries, and of the
Incorporated Midwives’ Institute, with six persons appointed by
the Privy Council. This Board is to make rules and regulations,
subject to the approval of the Medical Council, for examining. and
registering candidates, and for maintaining discipline amongst
registered midwives.
Practice is not Protected, but the use of the title “midwife”
is prohibited in very much more explicit terms than is the title
“chemist” by the Pharmacy Act, 1868. An unregistered woman
implying that she is registered becomes liable on summary
conviction to a fine not exceeding £5, and — admirable
draughtmanship — it is provided that the cost of prosecuting
the offender shall be borne by the county fund of the district in
which the prosecution takes place. One omission may be indicated
however — no specific prosecutor is mentioned. That this is a very
serious error is shown by the experience obtained under the 17th
Section of the Pharmacy Act, 1868. What is anybody’s business is
nobody’s business, and unless there is some inducement, local
authorities will not be keen in burdening the county funds with
the cost of vindicating a title.
The Midwives Board is to be authorised to levy registration
and examination fees subject to the approval of the Medical
Council, and is empowered to use its income in defraying the
expenses of carrying out the provisions of the Bill. The subtle
minds which evolved the Bill were, however, impressed with the
possibility of expenditure exceeding revenue — a circumstance not
unknown in examining and registering bodies — and to meet such an
eventuality it is provided that any deficiency shall be supplied from
the local county funds in proportion to the number of registered
mid wives in the particular county. Nor is this the only service
which the public is to render in return for the privilege of engaging
(and paying for) registered midwives.
Every Local Sanitary Authority in England and Wales — for
the Bill proposes to leave out Scotland and Ireland — is to be charged
with the duty of exercising supervision over the midwives, to
report irregularities of practice, and to furnish the Registrar of
the Board with notification of the death or removal of registered
persons. Altogether the Bill is calculated to be a great success —
for the Board, which, secure against deficiencies, will be free to
develop its actual and vicarous functions unvexed by that
“ eternal want of pence,” which is said to militate against public
men. Whether the local authorities, medical men, or the public
stand to benefit very much by the measure may be open to
question.
The Companies Bill passed its second reading in the House of
Lords on the 11th inst., and has been referred to the Select Com¬
mittee of last Session, which has been re-appointed for the purpose.
All this is in accordance with the anticipations expressed in these
columns. It is noticeable that the “ title ” clause has not yet
re-appeared, but no doubt the Pharmaceutical Society will take an
opportunity of approaching the Committee on the subject.
The Dangers of Calcic Carbide, and especially of the
imported variety of the substance, have been very fully set forth
in the Pharmaceutical Journal in the notes on Professor Lewes’
lecture on “ Illuminants ” {ante, p. 65). These dangers can no
longer be ignored, for they grow with the growth of the demand
for carbide, and it is quite opportune for Mr. Kearley to ask the
authorities what steps are being taken to regulate its storage. We
would advise the honourable gentleman to insert “conveyance
and ” before “ storage,” for a sea voyage is very trying to a sub¬
stance so sensitive to moisture, and the generation of phosphoretted
hydrogen would not be surprising in a foreign sample carelessly
packed. In default of better provision for safety, Mr. Kearley
suggests that Clause 14 of the Petroleum Act be applied to carbide.
A National Physical Laboratory was the subject concerning
which a deputation, including Lord Lister and other scientists,
waited upon Lord Salisbury at the Foreign Office on Tuesday, the
idea being to induce the Government to find funds for the founda¬
tion and maintenance of such a laboratory. Professor Riicker
intimated that the initial outlay would be £30,000, and the
annual cost of maintenance £5000. Lord Salisbury, in reply,
said the subject was not second in importance to any that
he knew of, but the Chancellor of the Exchequer was absent
at an important Committee, and he could not pledge him
in his absence, though he thought he could assure them of
Sir M. Hicks-Beach’s sympathy. Professor Rucker had omitted
two important words which appeared in the printed state¬
ment before him. The amounts named were those required
“at first” as being more urgent and at once necessary to meet
the exigencies of the case. Thus a growing vista of possible
expense was opened, and he had known modest movements started
with thousands and ending in millions. A duty which the State
had always acknowledged was that of standardising, and the legis¬
lation for stopping adulteration was really a branch of that
standardising work. He threw out as a suggestion that instead of
asking the Chancellor of the Exchequer to pledge himself to outlay
to which no bounds were set, some limited scheme of standardising
should be pressed upon the State, and the question of general
research reserved or allowed to depend on private munificence.
Feb. 20. 1897]
PHARMACEUTICAL JOURNAL.
155
THE WORLD Op PHARMACY.
■ - ♦ - —
BUSINESS MEETINGS.
School of Pharmacy Students’ Association, Friday,
February 5.—? Mr. Wilfrid Lean in the chair. — Mr. S. C.
Hovenden read a paper on — -
Artificial Light.
He showed that one of the most primitive forms of illumination
was the rush light, which was made by dipping the stem of a rush
in a cauldron of melted fat, and obtaining a thick coating of fat
round the rush, which formed the wick. The rush light was
succeeded by the tallow candle, the fat used being beef and
mutton suet, and the wick made of cotton ; there were numerous
objections to this. 1. The low melting point of the tallow and its
oily nature. 2. Irritating fumes produced due to the glycerin in
the tallow being decomposed and yielding acrolein. Candles are now
chiefly composed of stearic acid, which is one of the constituents
of tallow and other fats ; it has a higher melting point than tallow,
namely, 159° F., and the gases produced by the destructive dis¬
tillation of stearic acid in the flame of the candle burn with a
brighter flame than those produced from tallow. Those candles
known as “ Composite” consist of a mixture of stearic and
palmitic acids. The wicks of candles were a great source of trouble
at first, since the cotton wicks showed a great tendency to stand up
above the body of the candle till they came in contact with the air.
One method to obviate the long wicks was to soak them in solution
of nitre so that they provided their own oxygen, but if the solution
were slightly too strong the wick disappeared in the fat, and the
flame was extinguished. Another method, invented by Messrs.
Palmer, of London, was to have a thin bismuth wire running
through the wick, which fused at its end; forming a small knob
and causing the tip of the wick to bend and come in contact with
the air. The cottons of the wick are now plaited together and the
wick tends to bend naturally. Candles have been generally
succeeded by lamps, colza or a variety of petroleum oil being
burnt in them, though a primitive lamp was at one time used con¬
sisting of a bowl of rancid olive oil, the wick being kept afloat by
passing through a cork or some other buoyant substance. In all
the flames mentioned above the light is due to the incandescence
of carbon particles liberated by the decomposition of various
hydrocarbons in the flame, and in ordinary coal-gas flame the
light is likewise due to this, but we can have it derived from the
incandescence of other bodies heated in atmospheric gas burners, an
example of this being the Welsbach mantle, consisting of zirconia
or thoria, with a small percentage of ceria.
School of Pharmacy Students’ Association, Friday,
February 12. — Mr. Wilfrid Lean in the chair. — Papers were read
by Messrs. Morgan and Smith on “Crystallography” and “Our
Mother Tongue ” respectively. Discussions followed each paper,
in which the Chairman, Secretaries, Messrs. Matthews, Morgan,
Nelson, Perredes, and Tebbutt took part.
Chemists’ Assistants’ Association, Thursday, February 11.
— Mr. Charles Morley, President, in the chair.— The item down
on the programme for this meeting was ‘ ‘ Short Papers by
Members,” and the first communication took the form of some
Suggested Improvements in the Rules of the C.A.A.
tendered by Mr. Walter A. Tasker, one of the new members
elected at the commencement of the Session. His first suggestion,
on the acceptance of anonymous papers, was put forward on
the grounds that it would probably induce many of the younger
members to submit communications to the Association, and thus
the interest of those who being shy would otherwise remain silent,
would be strengthened. This idea was strongly condemned by
the President and several other members, their reasons being that
communications to which the authors were either afraid or ashamed
to append their names would be better appreciated if they
remained unread, save by the authors themselves. A few sugges¬
tions for the comfort of members, particularly those fresh from the
provinces, were received with more favour, although it was
generally agreed that smoking at meetings as recommended by
Mr. Tasker, while being appreciated by some, would probably be a
source of annoyance to others, and therefore it would not be wise to
establish the practice. The formal introduction of new members to*
the President at the meetings was suggested as being a means where-
by older members could make their acquaintance, and by a few
friendly words help to make their first meeting more enjoyable.
This idea was thought to be a good one. The retention of members
was next considered, Mr. Tasker’s suggestions receiving the
approval of most of the members present, the principal idea being
that by the payment of a nominal or a life subscription a man who
having once become a member might, when not residing in London,
still retain his membership, and consequently his interest in the
Association. The establishment of a “Bureau d’Emploi,” while
being fully acknowledged to be an excellent suggestion, was
thought by the President and others to be hardly practicable, at
any rate under the present conditions of the Association. The
advisability of forming a “ trade section” on the lines of a trade
union to protect the interests of assistants was rather doubted by
Mr. C. Morley, Mr. C. E. Robinson and others, the opinion being
expressed that there are very few professions or businesses in which,
the relations between masters and assistants are so good as in>
pharmacy. The suggested formation of a branch of the “Galen*
Lodge ” for chemists’ assistants was heartily approved, and a sug¬
gestion that a member of the Galen Lodge be invited to read a
paper on the subject during the next session will probably be
considered by the Council. In submitting these suggestions, Mr.
Tasker laid no claim to originality, but offered them in the hope
that they might be favourably considered by the members and
Council, and that as a result the Association would increase in.
usefulness and popularity.
A short paper was then read by Mr. S. Summers on the
Life and Work of Dr. William Harvey.
It was most interesting, and delivered in a very pleasing manner..
Commencing with Dr. Harvey’s birth at Folkestone in the year 1578,
Mr. Summer gave a brief outline of his career as a student at King’s
School Canterbury, Cambridge University, and at the famous
School of Physic at Padua under the renowned anatomist Fabri-
cuss, where he took his M.D. degree in 1602. Returning to-
England, he took the M.D. degree at his old University, and*
shortly afterwards was admitted a Fellow of the Royal College of
Physicians, and in 1609 was appointed to the staff of St. Bartho¬
lomew’s Hospital, his duties being, as he quaintly expressed them,
“to attend the hospital one day in the weeke at leaste
through the yeare, or oftener as neede should requyer, and
to prescribe only such medicines as should doe the poore good with¬
out regard to the pecuniary interests of the apothecarey.” In 1615'
he was appointed Lumeleian Lecturer to the Royal College of
Physicians, and in the following April delivered at the college in
Knightrider Street the series of lectures setting forth his ideas
with regard to the circulation of the blood, the notes of which,
occupying ninety-six pages of closely-written matter, are preserved
in the British Museum. In 1618 he became Physician Extra¬
ordinary to James I., and ten years later his work on the circula¬
tion was first published at Frankfort. During the year 1642 he left
London in attendance on Charles I. , and was present at the Battle
of Edgehill, after which he resided for a time at Oxford, taking
his M.D. degree in 1642, and becoming Warden of Merton College
in 1645. Harvey built the library for the College of Physicians in
1654, in recognition of which his statue was erected outside the
College. He died in 1657 and was buried at Hempstead, an oration
being delivered in his memory every year. Mr. Summer exhibited a
copy of the first English edition of Harvey’s great work which was
published in 1653, a fellow copy of which was sold in 1892 by
auction for £40 10s. He gave a general description of the book
and the work of Harvey, concluding with a passage from Lachary
Wood’s Preface, which is a quotation from Galen, “The cunning
of Nature in the fabrick of man’s body is so great, that though
great men have diligently and constantly searched after it, have
they not found it all out.”
Dispensing Query.
After the President had commented on the paper, Mr.
Summers said that recently he had been asked to prepare a
six-ounce mixture in which half a drachm of essence of lemon
was prescribed. He wished to know what should be dis¬
pensed in such a case. Several members thought the oil of
lemon of the B.P. was the correct thing to dispense, but the
President seemed inclined to think that it should be oil of lemon
in spirit, the same proportion to be used as in the case of essence
of peppermint of the B.P. Mr. Summers said he held the same
opinion as the President, and prepared the mixture accordingly.
156
PHARMACEUTICAL JOURNAL.
[Feb. 20, 1897
Brighton Junior Association of Pharmacy, Wednes¬
day, February 10. — A lecture on the “History of Tea” was
delivered by Mr. P. M. Short, who described the methods of
cultivation and preparation of tea in Ceylon. After giving a
graphic description of the laying out, draining, planting, etc., of
the plantations, he explained the various operations through which
the leaf has to pass before it is ready for the teapot.
Midland Chemists’ Assistants’ Association, Wednes¬
day, February 10. — Mr. F. H. Alcock read a paper before the
members of the Midland Chemists’ Assistants’ Association, at the
Exchange, Birmingham, on
The Life of a Plant.
By a series of well-prepared slides, which were worked by Mr. J.
Davis, Summer Lane, Mr. Alcock traced the life of a plant from its
birth to its final decay. In all there were thirty-nine slides,
among the more important being illustrations of the volvox-
globatar, specimens of the diatoms, cells and spores of the
lycopodium, hairs of the cotton, and glandular hairs of several
plants, including the drosera. A number of illustrations showing
the great division of the vegetable kingdom followed, and included
the pine, clematis, maple, marestail, sarsaparilla, and rush.
Sections of the various kinds of tissue were also exhibited,
in eluding starch cells, stomata, pollen, seaweeds, and the common
moss. Alternation of generations occupied some little time, and
concluded with the reproduction of the chief types of plants. A
brief discussion followed the reading of the paper, and at the
conclusion, a vote of thanks was passed to Mr. Alcock.
Edinburgh Chemists’, Assistants’, and Apprentices’
Association, Friday, February 12. — Mr. James McBain,
President, in the chair. — Mr. George Sinclair read a paper on
“Progress in Pharmacy,” which was followed by Mr. W. Make¬
peace Locke’s paper on “The Profession of Pharmacy, from an
Assistant’s Point of View,” which appears at page 143. The
reading of the papers was followed by a discussion, taken part in
by Messrs. Brand, Currie, Hill, Kidd, Locke, Lunan, McBain,
Macpiierson, Reid, and Sinclair.
Proprietary Articles Trade Association (Leicester),
Tuesday, February 16. — Mr. T. Howard Lloyd in the chair.- — A
meeting of the chemists of Leicester and district was held in the
Clarendon Rooms, Grandy Street, Leicester, for the purpose of
hearing an address from Mr. W. S. Glyn- Jones as to the aims and
objects of the Proprietary Articles Trade Association, and to
discuss the advisability or otherwise of forming a local chemists’
association. The Chairman having explained the object of the
meeting, said they all realised the importance of trying to bring
about a better state of things in respect to the profits on the sale
of proprietary articles, and the P.A.T.A. seemed to have come for¬
ward in the nick of time with an excellent suggestion of how it
was to be done. Some chemists were perhaps in that happy
position that they were more or less independent of the sale of
proprietary articles, and could afford to decline to sell
them, but he thought the majority of chemists would
be very glad to see a better state of things prevail
in regard to the profits on proprietary articles. The manner in
which those articles were advertised so impressed them upon the
minds of the public that they believed all that was said of them.
Therefore, he did not think they could look for relief by selling
their own “ substitutes,” but must try, by combination, to realise
larger profits on those articles. — Mr. Glyn-Jones, in the course of
his address, said chemists had the remedy in their own hands, and
he believed when their numbers had sufficiently increased and
large proprietors saw that they were determined in their opposition
to the present system of business, they would have no difficulty in
achieving the object they had in view. — Mr. Thirlby moved the
following resolution : —
“That this meeting of chemists residing in Leicester and the neighbourhood
cordially approve of the aims and objects of the P.A.T.A., and pledges itself
to support it in every possible way.”
He thought it was most unfortunate that they had no associa¬
tion in Leicester, and it behoved the chemists of the
town to help the P.A.T.A. in its good work. — Mr. Berridge
seconded, remarking that he did not see how any chemist could do
other than sympathise with the aims and objects of the P.A.T.A.
—Mr. White did not think they need trouble about the prices of
proprietary articles, but should rather direct their attention to try
and stop the cutting of drugs. With regard to the show cards of
patent medicines, he made it a rule to exhibit the show card of
no firm unless he received a guinea a year for so doing. At the
present time he had thirteen show cards in his shop, for which he
received thirteen guineas per annum. He thought if chemists
generally would adopt the same rule they would do some good.—
Mr. Goodess supported the proposition. — Mr. Clarke was not
sure whether they were adopting a wise course, and thought the
question of dealing with proprietary articles was one that should
be approached with great carefulness. After further discussion
the proposition was carried, and a small committee was formed with
the view of forming a local association.
Western Chemists’ Association (London), Wednesday,
February 17. — Mr. J. W. Taplin, President, in the chair.— Mr.
R. H. Parker opened a debate on— /
W ill Legislation Help Pharmacy ?
He contended that parliamentary legislation will not greatly
assist pharmacy, and that pharmacists must look to themselves if
they desire to improve their position as a body. Little sympathy
is to be expected from the House of Commons so long as the direct
representation of pharmacy in the House is so small, and especially
while there are so many representatives in Parliament who are directly
interested in opposing the passing of any pharmaceutical legisla¬
tion. Referring to the practice of dispensing by doctors, Mr. Parker
quoted the remarks of Dr. Rentoul, M.P. , on the subject, who
holds that no chemist is properly qualified to prescribe for the
slightest ailments, but that medical practitioners are both quali¬
fied and have a legal right to dispense their own prescriptions.
While influential Members of Parliament hold such opinions Mr.
Parker thinks there is not much hope for any beneficial legisla¬
tion in that direction. Speaking of the Pharmacy Act, he
said all impartial persons would admit that the spirit of
the Act is against company pharmacy, yet they knew how
it is interpreted by the legal mind. Then, with reference to recent
legal decisions in connection with the arsenical soap and other
cases, the decisions of the various magistrates had been ridiculous
in the extreme, and had brought to mind the old saying, that ‘ ‘ the
lawisahass.” From remarks made by coroners it would seem
they are ever ready to kick the chemist whenever he is in any way
involved in a case brought before them, even though no direct
evidence against him is produced. The coroner often censures
the chemist, who perhaps has supplied a soothing mixture for
a child that subsequently dies, and he as much as says “We
will let you off this time, but don’t do it again.” Mr. Parker
thinks that if the future prospects of pharmacy depend
upon the fostering efforts of legislation, the outlook is poor
indeed. The future development of pharmacy and the success
of the pharmacist rest with the profession, individually and
collectively, and the most important factor to attain this object is
education. The secret of the success of such countries as Germany
and Japan lies in that, and the man who knows his business and
keeps abreast with the times in educational and other matters will
be amply rewarded, independent of what legislative enactments
may be in force. It is necessary to utilise legislation for the pre¬
vention of fraud, but pharmacists must keep a sharp look out that
other people do not run Bills through Parliament that will be
detrimental to pharmacy. In conclusion, Mr. Parker said that
legislation will not help pharmacy much, but fortunately by sound
education and friendly intercourse pharmacists can help themselves
without its assistance.
Mr. J. C. Hyslop, whose duty it was to oppose Mr. Parker,
found himself to be very much in accord with the opinions ex¬
pressed by him ; still, he thought the paper bristled too much with
pessimism. Coroners, he agreed, treat chemists very unfairly, and
overstep their duties again and again, but if the chemist would
stand upon his dignity and when attacked would defend
himself, and at the same time point out to the coroner
that his duty is not to find out or prove the guilt of
anyone, but simply to discover the cause of death, Mr. Hyslop
thought he would soon be brought to his senses. In regard to legis¬
lation, he was of opinion that it is not evenly balanced as between
pharmacists and the public, as the latter get too much advantage
and the pharmacist too little. Those who handle drugs and
poisons ought all to be placed on the same basis, and should be
thoroughly educated men as well as legally qualified, and a name
should be given them to indicate that they are really
important to the public welfare. — Mr. Warren agreed with most
of the remarks previously made. With regard to coroners he
Feb. 20, 1807]
PHARMACEUTICAL JOURNAL.
157
thought pharmacists should stand up for themselves ; the most
inoffensive and upright pharmacist may be attacked for the exer¬
cise of his legitimate duties, but if they will stand upon their dignity
-coroners will begin to understand that chemists are not a lot of
worms to be trodden on without protest. It is not good to depend
too much upon legislation. Pharmacists have powers to improve the
education of the coming members of the craft, and in that way get
■legislation to consolidate them as a body.— Mr. Andrews questioned
-very much if legislation and the Pharmacy Act of 1868 has benefited
pharmacy. He thought pharmacists on the whole do not hold a
very much higher position than they did previous to that Act, and
that legislation had a tendency to make people rest upon what
they had done instead of steadily progressing. Education will
improve the pharmacist if it does not improve pharmacy.- — Mr.
Tallin did not agree that legislation has not done much for
pharmacy. He said he believed it has done much to improve the
-character and position of pharmacists.
Mr. Parker, in replying, agreed that the educational side of
legislation has been very beneficial to pharmacy. Also that only
those who are qualified should be allowed to handle drugs. He
ithought, with regard to coroners, that the Pharmaceutical Council
should make it known that they would take into consideration any
case where a coroner’s inquest was held, and to prepare the
chemist to go through with the ordeal. The consolidation of
chemists, he thought, is very desirable.
SOCIAL MEETINGS.
Aberdeen and North of Scotland Society of Chemists
sand Druggists, Tuesday, February 9. — At the annual assembly
held in the Trades Hall Buildings, Belmont Street, the first half
*of the entertainment took the form of a concert, under the chair¬
manship of Mr. James Clark, pharmaceutical chemist, Union
-Street, who in a few appropriate sentences bade the company
welcome. The various artists rendered their several songs with
marked ability. Promptly at ten o’clock the company adjourned
ito the large hall, where dancing was engaged in by about seventy
couples till 2.30 a.m. Messrs. Bremner and Leslie courteously and
efficiently discharged the duties of M.C.’s. Stewart’s Quadrille
Band supplied excellent music. The assembly was much enjoyed.
Air. J. Cruickshank for the Senior Society, and Mr. C. Philip for
the J unior discharged the duties of Secretaries.
Birkbeck Institution, Saturday, February 13. — The students
connected with this institution held a most successful conversa¬
zione, which was attended by considerably over a thousand people.
Every preparation had been made for the entertainment of the
visitors, there being no lack of things to interest and instruct from
-the moment of entering the large hall, where the Hon. Mr. Justice
Bruce (Vice-President of the Institution), supported by the
Principal and Council, held a reception, until the time of leaving
at 11 p.m. The programme comprised a variety of means of
entertainment to suit all dispositions. For those of a scientific
turn of mind there were lectures on “Liquid Jets,” by R. S.
Olay, B.A., B.Sc. ; the “ Phenomena of Combustion,” by j. Wood¬
ward, B.A., F.I.C.. F.C.S. ; on “Insect-Eating Plants,” by A. B.
Rendle, M.A. , B.Sc. ; “Flat-irons and the Spheroidal State,” by
F. J. Cheshire, who at the conclusion of the lecture plunged his hand
into molten lead to illustrate the ancient custom of “Ordeal by Fire.”
“‘Acetylene, the Latest Illuminant,” by F. Gossling, B.Sc., F.C.S. ;
and the “ Birth of a Crystal,” by G. F. Harris, F.G.S. In addition
to the lectures, numerous experiments were performed in the
laboratories, such as the liquefaction of oxygen and air, the melt¬
ing of metal without heat, freezing a metal in a red-hot vessel,
■etc. , etc. There were also concerts and dramatic entertainments,
musical sketches, displays of animated photographs, and demon¬
strations with the Rontgen X rays. By means of the electrophone
visitors were enabled to hear a variety of performances taking
place in London, and by the aid of the latest Edison-bell phono¬
graph tfiey could listen to speeches, songs, etc. , by leading politi¬
cians and singers. In the exhibition were shown pictures, Post
'Office telegraphic instruments, engineering models, a motor car at
work, glass-blowing by a professional glass-blower, the Wimshurst
electrical influence machine, and the new system for connecting
lightships with shore stations. Refreshments were not overlooked
■by the Executive Committee, and, in fact, nothing seemed to have
"been neglected in order to ensure for everyone a very pleasant
:and profitable evening.
LEGAL INTELLIGENCE-
Hunyadi Janos and Uj Hunyadi Waters.
The action of Saxlehner v. the Apollinaris Company, which has
been for some time pending, came before Mr. Justice Kekewich for
trial on Tuesday, February 16. Mr. Warmington, Q.C., Mr.
Neville, Q.C., and Mr. Sebastian appeared for the plaintiff, and Sir
Frank Lockwood, Q.C., Mr. Warrington, Q.C., and Mr. John Cutter
for the defendants.
Mr. Warmington, in opening the case, said it was an action to
restrain the defendants from passing off mineral water other than
the produce of the plaintiff’s springs as Hunyadi Janos, and he must
give a short history of the facts out of which the proceedings arose,
because he thought a scheme must have been devised some ten
years ago, which came into operation in March last. The present
plaintiff' was Mrs. Saxlehner, widow and successor of Andreas
Saxlehner, who died in 1889. He, in 1863, purchased certain
estates near Buda-Pesth, and shortly afterwards sunk wells and
placed upon the market the mineral water thence obtained, to which
he gave the title Hunyadi Janos, being the name of a Hungarian
hero who flourished in the thirteenth century, and which was a
purely fancy word as applied to mineral water, and had never
before been so used. The trade rapidly developed, and in 1869
or 1870 the water was introduced into England and sold in
considerable quantities by several agents. A trade mark was
registered in Buda-Pesth, with the portrait and name Hunyadi
Janos, and the water was exclusively known in the United King¬
dom under that name. In 1875 Mr. Steinkopf, one of the founders
of the defendant company, entered into negotiations with Mr.
Saxlehner with a view to that company being the sole importers
into the United Kingdom of the Hunyadi Janos water, and in
1876 an agreement for ten years was concluded (subsequently
extended until March 25, 1896, when it was terminated by notice
from the Apollinaris Co.), under which the defendant company
became the sole importers and agents for Great Britain and her
colonies and foreign possessions for the sale of Mr. Saxlehner’s
produce. The learned counsel read several particulars of the
agreement in question, which made it clear that the words “Hun¬
yadi Janos” only applied to the produce of the Saxlehner’s
springs. In June, 1876, the defendant company registered two
trade marks, the only difference in them being the language in
which they appeared, which were simply a reproduction, with
slight variations, of the original mark registered in 1863 by Mr.
Saxlehner, and it was used as a conspicuous part of the label under
which the water was sold all over the world by the defendant com¬
pany. These trade marks were also registered in America, but
there Mr. Saxlehner was registered as the owner. Under these
trade marks the defendant company pushed the trade, and expended
large sums in advertising the water. In January, 1885, proceedings
were taken by the defendant company against another company called
the Anglo-Hungarian Mineral Water Co., Ltd., and in that action
Mr. J. C. Prince, then managing director of the defendant
company, made an affidavit, in which he said that the only mineral
water known in England under the name of Hunyadi Janos
was the produce of the springs of Mr. Andreas Saxlehner, the sole
right to sell which in the United Kingdom was in the Apollinaris
Company. In that action a perpetual injunction was granted, and
an agreed sum paid for costs ; the ground for the action being the
sale by the defendants to that action of a water bearing a label de¬
scribing it as Rakoczy, with the addition of the word “Janos,”
which was alleged and held by the Court to be likely to deceive
the public. But the present defendants subsequently acquired the
property on which the Rakoczy springs were situated, and were
now seeking to foist it on the public, associated with the name of
Hunyadi. In 1887 proceedings were taken by the Vichy Co. to
expunge the Apollinaris Co.’s trade marks from the register, and
in December, 1890, the Court of Appeal made an order expung¬
ing the marks, one of the grounds being that the Apollinaris
Co. could not be the owners of the marks, the real proprietor
being Mr. Saxlehner. Meantime, in 1887, an action was com¬
menced, and was still pending before Mr. Justice Stirling, in
which various questions were raised as to the respective rights
of Mr. Saxlehner and the Apollinaris Co. under the agreement of
1876. It was not necessary to go into that action in detail, but
about the same time the defendant company began their attempt
to filch the reputation of Mr. Saxlehner, the first step being to
register a new trade mark of their own, which they called a “ mark
of selection,” consisting of a red diamond, and thenceforward they
158
PHARMACEUTICAL JOURNAL.
[Feb. 20, 1897
endeavoured by advertisements, circulars, etc. , first to confuse the
genuine Hunyadi Janos water with other Hungarian mineral
waters, and finally to attach the reputation which it had obtained
to any water which they might sell under their red diamond mark.
A large number of these circulars, letters, invoices, and advertise¬
ments were read showing the gradual attempts made by the
defendant company in the direction indicated. Mr. Warmington
then proceeded to narrate what had taken place in Hungary,
beginning with the acquisition by Mr. Steinkopf, on behalf of the
defendant company, of a small piece of ground on which were
situated the Rakoczy springs, and including a statement of the
trade mark law of Hungary, and of the pi'oceedings taken by the
present plaintiff to expunge various marks from the register which
interfered w ith her trade mark Hunyadi Janos, one of such mis¬
leading marks being Uj Hunyadi, registered by Mr. Steinkopf in
Pesth. The result of all these proceedings was that no one in
Hungary could sell any mineral under the name of Hunyadi Janos,
except the plaintiff. In 1895 an amending Act was passed in Hun¬
gary cancelling the prohibition in the previous Act of trade marks
consisting of words or names, and Messrs. Prince and Steinkopf
then registered a company in Hungary called the Uj Hunyadi, in
which Air. Prince held 1194 shares out of 2000, and a company under
a similar name in England, and then again registered trade marks in
Hungary, of which the words Uj Hunyadi were the principal
feature. The plaintiff again took proceedings, and in August, 1896,
judgment was given cancelling all such marks. Coming back to Eng¬
land, the defendants, in 1895, gave twelve months’ notice to terminate
the agreement on March 25, 1S96, and in the latter part of the year
1895 the defendants began to prepare for their course of action
when the agreement was determined, and in November, 1895, they
issued an advertisement headed “Hungarian Aperient AVater,”
in which they informed the trade that they had given notice to
terminate their contract with Mr. A. Saxlehner, the proprietor of
the Hunyadi Jano spring; that they had arranged to supply
aperient water drawn from springs in the neighbourhood of Buda-
Pesth, called the Uj Hunyadi springs, that such water would
bear the trade mark “Apenta,” and that they were confident such
water would be superior in every respect to any similar
water now offered for sale, and that it would be sup¬
plied on terms which would defy competition. Further
advertisements of a like character followed, in some of which it
was stated that the springs were the property of the Uj Hunyadi
Co., Limited, of Buda-Besth, and that the water was bottled
under the supervision of the Royal Hungarian Chemical Institute,
Ministry of Agriculture, which was untrue, and a label they
sought to register in Hungary bearing that statement was refused
on that very ground. On October 1, 1895, an application was
made to the public authority of Buda-Pesth by the agent of Mr.
Steinkopf for permission to call the springs hitherto known as
Rakoczy and Stephania by the name of Uj Hunyadi, the result of
which appeared to be that such permission would have to be
obtained from the Minister of Commerce, and that no application
had been made. The last event which happened at Buda-Pesth in
connection with the matter was the seizure on February 5 last, by
plaintiff, of sundry bottles, corks, and capsules on the premises of
the defendant company, bearing the words Uj Hunyadi. This
was not, however, a final decision, further proceedings being still
"pending. Having shortly referred to one or two of the leading
eases on the subject, Mr. Warmington made a few remarks on the
defence set up on the other side, and then at Mr. Lockwood’s
suggestion read letters which had passed quite recently between
the solicitors, in which the defendants, on January 27 last,
expressed their intention, in consequence of recent decisions in
Hungary, to give up the use of the word Hunyadi on their labels.
Mr. Justice Kekewich remarked that in view of this offer, it
seemed as if he had to try the action simply for the sake of
deciding the question of costs.
Mr. Warmington said he could not quite admit that, and after
some further discussion the case was adjourned.
On Wednesday the case was continued, and several witnesses
were called on behalf of the plaintiff, including M. Richter, the
manager of plaintiff s business in Buda-Pesth, Mr. Michael Car-
teighe, Mr. J. J. Snook, trading as Wilcox and Co., Mortimer
Street, formerly of Oxford Street, and also as Gabriel Jozeau,
Haymarket, their evidence going to show the identification of
Saxlehner’ s mineral water by the name of Hunyadi Janos and the
possibility of the public being deceived by the defendants’ labels.
Dr. Darvai, a legal gentleman fromBuda-Pesth, was next called to
prove the law of trade marks in Hungary, and the various judg¬
ments given there. •
Sir. F. Lockwood objected to the admissibility of a good deal of
this evidence, and his Lordship said he thought the objection valid*
but it would be safer to let the evidence be given.
Mr. Walter Hills, and Mr. Hy. Hillier, Manager to Messrs,
Allen and Hanburys, also gave evidence as to the association of the
name Hunyadi Janos with Saxlehner’s produce, and the further
hearing was again adjourned.
Caffeine Iodol. — Not the least remarkable attribute of iodo¬
form is the number of “substitutes ” that it has called into exist¬
ence. Among these we must now class caffeine iodol, alight grey,,
odourless, tasteless powder, almost insoluble in ordinary solvents.
It is prepared by the reaction of equivalent weights of caffeine and
iodol in alcoholic solution. In addition to being used externally
for all the purposes to which iodoform is put, it is also prescribed
internally instead of potassium iodide. Pham. Ze.it., xli. , 49/.
SopiUM Chlorate in Uterine Cancer. — As a palliative in the
treatment of cancer of the uterus, Duvrac has found sodium
chlorate of service. It is given internally in the following mix¬
ture Sodium chlorate, 5 drachms ; syrup of orange flowers,
8 drachms; distilled water, 3 ounces. Mix. From two to eight
tablespoonfuls to be taken daily, commencing with the smaller
dose and gradually increasing up to the maximum. Local appli¬
cations are also made with the following powder Sodium
chlorate, bismuth subnitrate, of each 2J drachms ; iodoform,
1 drachm. Mix. A small quantity of this is applied on a tampon
to the cervix. It is also applied on strips of sterilised tailatan
impregnated with 1 part iodoform, 20 parts sodium chlorate, and
20 parts glycerin. Lastly, a vaginal douche of a quart of boiled
water having in solution 150 grains of sodium chlorate in solution,
is used once daily. Under tliis treatment metrorrhagia and foetid
discharge disappear almost completely, and pain ceases, the
appetite and general health improve, and patient enjoys compara¬
tive comfort. The effect of the treatment is, unfortunately, only
palliative, the course of the disease being unchecked in the deeper
tissues, which cannot be reached by the local dressings. B. M. J .
Epit. , 2/96/70, after Wien Med. Pre-sse.
Peroxide of Hydrogen in Oto-rhinology. — In treatment of
various affections of the nose and ears, Gelle (Soc. Franc, de Baring.,,
Ot. and Phin.) finds that peroxide of hydrogen is an excellent disin¬
fectant, and at the same time a reliable haemostatic. In epitaxis,
whether traumatic, surgical, or idiopathic, a plug of absorbent,
cotton freely moistened with peroxide is an efficient memos tat. In
the ear peroxide is an excellent disinfectant ; it removes pus
almost at once, and after surgical operations rapidly renders the
seat of operation bloodless. — Bullet. Gen. de Therap., cxxxi., 336.
Morphine Hydrochloride as Antidote to Potassium Cyanide.
■ — From experiments on white mice Heim finds that hypodermic
injections of the alksdoi dal salt have a distinct inhibitory action on
the poison, and under favourable circumstances may prove a
valuable antidote. This action is attributed to the formation of
oxy dimorphine and Prussian blue from the action of the iron and
alkali present in the blood. — Munch. Med. Woch., xliii. , 861.
Sodium Bicarbonate for Common Colds. — Dr. Bulkley (Med*
Record) finds bicarbonate of soda to be an infallible remedy for a
common cold. Twenty to thirty grains are given in water every
half hour for three doses, and a fourth dose an hour after the third.
Two to four hours are then allowed to elapse, and the four doses
may then be repeated as above. If necessary in another two.
hours the doses may be again repeated.
Whale Oil in Acne. — Whale oil possesses remarkable pene¬
trating powers, and according to Boeck appears to act to some
extent as a bactericide. He has found the following ointment^ of
service in the treatment of acne : — Powdered camphor, 30 to 50;
salicylic acid, 30 to 50 ; sulphur, 10 ; zinc oxide, 2 ; whale oil, 12
parts ; medicinal soap, 1 part. — The ointment is applied every
night, and washed oft' in the morning. — Ind. Med. Cliirurg. Rev.,
iv., 225, after Edin. Med. Joum.
Feb. 20, 1897]
PHARMACEUTICAL JOURNAL.
159
EXTRACTS FROM CONSULAR REPORTS-
“Molasses Mull,” a new cattle food, is described by Consul
Powell in a very interesting Foreign Office report for January,
1897. He says, the method of fattening cattle and sheep by feed¬
ing with molasses has for a few years past been largely experimented
on by agriculturists in Germany. One of the difficulties which had
to be overcome was that of obtaining the raw molasses with 50 per
cent, of sugar remaining in it, in consequence of the molasses
being subjected to a further process for the extraction of the sugar
after passing out of the original manufactory. Another question
•of even more moment was the difficulty of finding a proper medium
with which to mix the molasses, in order to counteract the purging
■effect which molasses alone, or in conjunction with some other
feeding stuff's, exercises on cattle when fed with it, even in small
■quantities. It is found that the- molasses (which have at present
been in the German market) contain injurious salts which are
prejudicial to the health of beasts. The latter difficulty has
apparently been met (although some are of a contrary opinion)
by a mixture of molasses with a dust (mull) obtained from the
moss-turf (peat). The dust, or “ mull,” is obtained from the moss-
turf by being torn up or teased out by a machine for making moss-
litter, called a “ Wolf.” It is taken from the upper strata of high-
lying peat moors, and consists largely of the dried but non-
decomposed fibre of the Sphagnum cuspidatum and the Eriophorum
Xatifolium. The acids contained in the moss-turf, more especially
the humic acids, neutralise the salts of proteine of potassium held
by the molasses and render them harmless, the action of the mull
being to counteract the severe purging caused by the molasses
alone, which is the chief objection to its use as fodder. It is
recommended by experts that molasses-mull fodder should first be
given in very small quantities increased to the following
amounts : — -
For—
Quantity.
Fattening Cattle .
Per head daily
6 lbs.
Milking Cows . . . .
Morses .
5 „
3 ,,
Sheep for fattening . .
n i,
i ,,
Sheep . .
Pigs .
Per 100 lbs. live weight.
i ,,
British and German Trade with the Niger Coast Pro¬
tectorate. — Consul-General Moor, in his report for the year
1895-96, gives some very interesting statistics in relation to the
import and export trade of the Protectorate, which tend to show
that the United Kingdom has up to the present maintained the
foremost position in the exportation of general merchandise and
especially drugs and medicines, in which her trade has steadily
increased, while Germany’s trade in these articles has decreased.
In perfumery, however, the German trade, although not so large
as the British, has increased, while the latter has decreased. The
trade in mineral waters and soap has gradually increased with
both countries, Britain heading the list in soap by over eight
thousand pounds value. The appended table will show at a
glance the trade positions of the two countries with the Pro¬
tectorate during the years 1S92-93, 1893-94* and 1895-96, the
year commencing April 1, and ending March 31.
Free Impotts into the Niger Coast Protectorate.
Articles.
V 2 -g
<3 o
&
1892-93.
1893-94.
1895-96.
o M
O kH
Qnty.
Value.
Qnty.
Value
Qnty.
Value.
Pkgs.
£
s.
d.
Fkg*.
£
s .
A.
[Pkgs.
£>
s.
cl.
Drugs and medicines
U. K.
480
3047
0
11
571
3592
3
1
740
4037
15
9
Ger.
11
19
n
5
16
52
16
3
8
11
i
9
Scientific instruments
U. K.
103
1(35
i
3
41
323
4
7
34
274
4
1
Ger.
1
(5
0
0
1
11
17
10
Mineral waters .
U. K.
1038
1328
1
2
1570
1874
10
5
2091
2118
4
11
Ger.
66
50
12
9
97
74
10
2
121
109
17
2
Perfumery .
U. K.
310
813
19
]o
252
595
9
1
513
527
5
9
Ger.
24
165
1
5
76
158
9
10
82
344
V
1
Photo, materials ....
U. K.
38
171
3
4
37
209
17
4
64
334
3
3
Ger.
1
11
4
0
1
3
16
0
1
4
3
10
Soap .
U. K.
53,042
5750
19
0
75,592
9216
4
11
87,262
8817
3
1
Ger.
912
65
9
1
1333
93
14
5
1901
102
2
5
* The statement of quantity and country whence imported is not
reported for 1894-95.
All Articles, Letters, Notices, and Reports Intended for
publication In the Journal, Books for Review, and com¬
munications respecting Editorial matters generally,
must, be Addressed “Editor, 17, Bloomsbury Square,
London,” and not in any case to Individuals supposed
to be connected with the Editorial Staff. Communica¬
tions for the Current Week’s Journal should reach the
Office not later than Wednesday, but news can be Re¬
ceived by Telegraph until I p.m. on Thursday.
The Benevolent Fund.
Sir,— May I be allowed to suggest that to celebrate the sixtieth
year of Her Majesty’s reign the Pharmaceutical Society take steps
to abolish this Fund, and as the old annuitants die off to increase
the annuity of those that are left by sharing the deceased’s por¬
tion until the annuitants and the Fund are all gone ? For one to have
the prospect of working at our calling until they are sixty or seventy
with the prospect of becoming annuitants, or leaving their families to
do so, is certainly very cheering, and another comforting consoling
thought is the fact of having a mansion prepared for us, eternal in
the— suburbs. If instead of raising a fund to wipe off debts on
hospitals and other charitable institutions, they would abolish
them, they would know the debts would be for ever gone, but as
long as money can be obtained to perpetuate the system of con¬
science quietening, and the thriftless and] improvident know they
can obtain relief, so long shall we keep in our midst workhouses
and other forms of so-called charities. What we ought as a body
to aim at is that we shall be paid for our services as servants in
other departments of the State, and if we cannot be recognised as
such and receive a pension, let us see to it that we are paid by the
public in such a way that we can not only make a living for ourselves
now, but make a provision for our old age ourselves. To this end,
if instead of emulating the cutters, the qualified men sought by
combination to get a proper remuneration for their services, and
not make themselves the tools of the capitalist to cut the ground
from under their own feet, then they ought to be able to look
forward for a peaceful retirement at the age of sixty, and not h a \ o
to rely upon any Benevolent Fund, supported by their willing and
unwilling brethren. In other branches of labour or profession
there are recognised prices to charge, and why chemists do not
combine in their own interests instead of cutting one another is
the surprise.
Torquay, February IS, 1897. W. J. Rawling.
“Business Ways that are Dark.”
Sir,— I also received a box by post containing packets of cachous
the same as “Anti-Soft Sawder.” As I had not ordered them and
never receive goods on sale or return, I sent a postcard, requesting
threepence in stamps to be sent for the return of the cachous they
had taken the liberty to send me. I received them by return.
Similar packets were sent to the grocers.
February 13, 1897. -A- J. P. S. (81/3).
Sir, — I was very pleased to see in your last week’s Journal a
letter signed “ Anti-Soft Sawder.” I myself had a parcel of cachous
sent me per post with the request that I would exhibit them on the
counter, but I resented the impudence by returning them at once.
Worksop, February 16, 1897. G. W. Jones.
The Keeping Qualities op Essence of Lemon.
Sir,— I am in a position to confirm the statement put forward by
Messrs. Typke and King in your issue of February 6 that “ natural
essence of lemon will keep good for a considerable time,” More-
over, it will do so though, no special care be taken to exclude light,
etc. In February, 1890, I had the opportunity offered by Messrs.
Chas. Southwell and Co., importers of lemons for confectionery
purposes, to collect myself several ounces of oil from Messina fi nit.
Since then this oil has been kept corked in a green glass bottle,
and to-day it possesses a finer aroma and flavour than even that of
one of the best known Palermo brands of this season s shipment
(1896-7). I enclose samples for your inspection. As I have not
met with any imported essence that has the same keeping properties
as that of my own extraction, I am forced to believe that adultera¬
tion is generally practised and to expect the de\ elopment more or
160
PHARMACEUTICAL JOURNAL,
[Feb. 20, 1897
less of the “ turpy odour.” The specific gravity of my essence
examined to-day was -862 at 15° C. ; its optical rotation viewed in
a 200 M.m. tube +123°.
London, February 10, 1897. H. H. Robins.
Check Tills.
Sir,— In reply to “ Inquirer,” I beg to say that I have had an
O’Brien’s check till in use for two years, and can confidently
recommend it as possessing great advantages over the ordinary
old-fashioned till. First, one never has any doubt but that what
has been put in the till can be accounted for. Secondly, if any
mistake arises in giving change, it can always be detected by
comparing the cash in the till with the entries on the slip. Thirdly,
if an account has been paid which has not been credited, it can
always be traced by turning up the cash slip for the particular
day on which the amount was paid. Fourthly, at the end of the
day one has invariably the satisfaction of knowing that the cash
in the till corresponds with the total of cash slip. Fifthly, it is as
a till much more convenient for giving change, as there are com¬
partments for gold, large silver, small silver, and coppers.
Sixthly, it is an ornament to the counter. In short, it supplies a
want, and no “up to date” business man should be without one.
Faringdon, February 15, 1897. W. R. Cook.
Sir,— In reply to “Inquirer’s” letter of last week, we recom¬
mend him to purchase “O’Brien’s Self-Closing Check Till.” We
have six assistants behind our front counter, and never have any
difficulty with change or balancing. The price is so moderate
that we do not consider it worth while attempting to convert an
ordinary cash till into a check one.
Wrexham, February 17, 1897. Francis and Co.
“A Personal Complaint.”
Sir, — In reply to Mr. John Onion’s complaint in your last issue,
the ball circulars were sent to the stewards and guarantors in
December last for distribution. I regret he has found it necessary
to trouble you with so trivial a matter. If he had written, or
called upon me on his way to the city, I could soon have satisfied
his sensitive mind that I have no desire to be anything but
courteous and friendly to any member of the Midland Pharma¬
ceutical Association. However, I shall be round his district
collecting subscriptions for the Benevolent Fund shortly, and will
give him a call.
Birmingham, February 16, 1897. Char. Thompson.
ANSWERS TO QUERIES.
New Pharmacopoeia. — It is said to be expected about the end
of the current year. [ Reply to Assistant. — 80/31.]
Sediment in Tincture. — This is a somewhat unnecessary
question. Any insoluble sediment should certainly be filtered
put. [ Reply to S. H. — 81/6.]
Cultivated Flowers. — Johnson’s ‘Gardeners’ Dictionary,’ by
Wright and Dewar (Bell and Son), and Sutherland’s ‘Hardy
Herbaceous and Alpine Flowers ’ (Blackwood and Son), or perhaps
Cassell’s ‘ Familiar Garden Flowers,’ may serve your purpose.
Please put your name in full if you should write again.
[Reply to E. C. E. — 75;30.]
Plants Identified. — (a) Mnium undulatum; (/S) Conidia of
Nectria cinnabarina; (y) probably a young specimen of Pellia
calycina; (5) Mercurialis perennis. Use numbers to distinguish
specimens instead of letters next time, and send older specimens of
such plants as the third. [ Reply to ipvrov. — 79/42.]
Botanist’s Pocket Book. — As the work is printed from stereo¬
types, the major portion of it is, of course, the same as in previous
reprints. The additions constituting what is new in the latest
reprint are contained in a supplementary page at the end of the
book. [ Reply to H. D. K. — 80/24.]
Hop Bitters. — Concentrated infusion of chamomile, 3 ounces ;
concentrated infusion of buchu, 2 ounces ; concentrated infusion
of hops, 8 ounces ; concentrated infusion of gentian, 3 ounces ;
glycerin, 3 ounces ; water recently boiled and cooled to make
48 fluid ounces. Mix. [Reply to D. A. — 80/10.]
Preservation op Herbarium Specimens.— A solution of mer¬
curic chloride, 2 grs., in methylated spirit, 1 oz., does not show.
In tropical climates double this strength is usual. A strong, de¬
colorised tincture of quassia will prevent the attacks of most-
insects, but not necessarily of all, and it will not prevent the
appearance of mould. [Reply to H. R. M. — 80/34.]
Use of a Still. — The terms of the Act are very wide in their
scope, an Excise duty of ten shillings being imposed 1 ‘ on every
person . . . who keeps or uses any still or retort.” The Commis¬
sioners are empowered to grant exemption from duty in the case
of stills or retorts kept or used for chemical experiments, and you.
should make application for such exemption through the nearest,
excise officer. [Reply to Retort — 81/8.]
Dulcified Spirit of Salt. — This is a very old formula ; under
the name of “ Spiritus salis dulcis,” it was official in the Edinburgh-
Pharmacopoeia. It was prepared from hydrochloric acid, 1 part ;;
rectified spirit, 3 parts. The mixed liquids are digested together,
for several days, then distilled, the distillation being repeated:
three or four times. The preparation is still sometimes asked for-
in the London wholesale trade. Its medicinal action is somewhat.-
similar to that of spiritus chloroformi. [Reply to Student. — 78/7.])
OBITUARY.
Nurthen. — On January 28, Frederick Richard Nurthen-,
Pharmaceutical Chemist, Strand, London. Aged 54.
Brown. — On February 2, Charles Hills Brown, Chemist and
Druggist, St. Peter’s Park London, W. Aged 61.
Huggins. — On February 3, George Thomas Huggins, Pharmaceu.-
tical Chemist, Barnet, Herts. Aged 71.
Kay. — On February 8, Thomas Wilkinson Kay, Chemist and
Druggist, Blackpool. Aged 36.
Southwell. — On February 8, Charles Henry Southwell, Phar¬
maceutical Chemist, Boston. Aged 49.
Downie. — On February 9, Henry Downie, Chemist and Drug¬
gist, Newcastle-on-Tyne. Aged 67.
Johnston. — On February 13, at No. 24, Rubislaw Terrace, Aberdeen,,
Isabella Farquhar Stuart, wife of Jchn Johnston, Chemist and
Druggist, and Member of the Pharmaceutical Council, 45, Union,
Street, Aberdeen.
PUBLICATIONS RECEIVED.
Short Studies in Physical Science. By Vaughan Cornish j,
M.Sc. Pp. 230. Illustrated. Price 5s. London : Sampson,
Low, Marston and Co., Fetter Lane, E.C. 1897.
Bericht uber das Jahr 1896. Herausgegeben im Januar, 1897-
No. 142. Pp. 191. Darmstadt : E. Merck.
The Tutorial Chemistry. Part I. Non-Metals. By G. H.
Bailey, D.Sc. (Lond. ), Ph.D. (Heidelberg). Edited by William
Briggs, M.A. Pp. 226. Price 3-s. 6 d. London : W. B. Clive,,
13, Booksellers Row, Strand, W.C. From the Publishers.
Aids to the “Study of Bacteriology,” by T. H. Pearmain.
and C. J. Moor, M.A. Pp. 159. Price 3s. 6d. London,
Bailliere, Tindall and Co., King William Street, Strand. From
the Publishers.
Guy’s Hospital Reports. Edited by E. C. Perry, M. A. , M. D. ,
and W. H. A. Jacobson, M.A., M.Ch. Vol. lii. , being vol. xxxvii.
of the third series. Pp. 230. Price 10s. 6 d. London, J. and
A. Churchill, Great Marlborough Street. 1896. From the-
Publishers.
Herbal Simples approved for Modern Uses of Cure. By
W. T. Fernie, M.D. Second edition. Pp. 652. Price 6s;
Bristol : John Wright and Co. 1897.
Elementary Bandaging and Surgical Dressing. By Walter
Pye, F.R.C.S., and G. Bellingham Smith, F.R.C.S. Seventh,
edition. Pp. 218. Price 2s. Bristol : John Wright and Co..
1896.
COMMUNICATIONS, LETTERS, etc. .have been received from
Messrs. Bird, Buckley, Cantwell, Chattaway, Cook, Coull, Cox, Crinon, Cruick-
shank, Davis, Dilworth, Dixon, Dunlop, Fisher, Gibson, Hill, Hills, Hogg, Hunt,
Jones, Ker, Lord, Moore, Paine, Philip, Rawling, Robins, Robinson, Rose, Rudd,
Russell, Skinner, Sowray, Thompson, Tocher, Waddington, Wilkie.
PHARMACEUTICAL JOURNAL.
161
Mj>\
TH^JMONTH.”
97 / ♦ . ■
The /citeijftitution of pilocarpine, as elabo-
Piloearpine.*-* -rated Hardy and Calmels, is doubted by
\/ /: ru A Kmidsen ( Ber. Deutsehen Phann.
Gesdlsch. , 04G.»>Efardv and Calmels have claimed that,
starting from pyridine lactic acid, which they state
is obtained by the action of boiling water on pilocarpine, they
were enabled to produce pilocarpidine, and this, on methylation,
was converted into pilocarpine. Hence they concluded that the
pilocarpine molecule must be produced from trimethylamine and
pyridine lactic acid. Knudsen has failed to synthesise pilocarpine
on these lines. Starting from picoline a-lactic acid, the higher
homologue of pyridine lactic acid, he could in no instance effect
the synthesis of pilocarpine or pilocarpidine. He considers, there¬
fore, that the views of Hardy and Calmels as to the constitution of
pilocarpine must be incorrect, and that their work on the
jaborandi alkaloids needs revision (Ber. Derut. Pliarm. Ges.,
G, 164). Following up Knudsen’s results, E. Merck ( Merck's
Ber., 1896) has examined the action of methyl iodide on
pilocarpidine (Harnack), but was unable to produce pilo¬
carpine, as stated by Hardy and Calmels ; he merely obtained
an isomer of pilocarpine, which is distinct from that base in being
insoluble in water. In this connection it must be remembered
that the pilocarpidine of the French chemists does not agree in
character with that of Harnack and Merck (Paul and Cownley,
Pli. J. , 57, 1 ). It is evident from these contrary statements that
there is still much work to be done in order to elucidate the nature
and constitution of the jaborandi alkaloids.
The increasing use of dimethyl ketone as a
Assay solvent in analytical and technical operations
of renders it a matter of some concern that an
Acetone. accurate method should be available for deter¬
mining its strength. Existing analytical
methods are based on the iodoform reaction, but commercial ace¬
tone generally contains other bodies that respond to that reaction,
one sample examined by L. F. Kebler containing 6 per cent, of
material (higher ketones ?) that possessed a boiling point of 80° C.
and above, yet proved on analysis by the usual methods to contain 20
per cent, of iodoform-yielding substances. The specific gravity is not
a trustworthy guide, since a number of products are formed during
the destructive distillation of the acetates, which possess practically
the same specific gravity as acetones. The boiling point is a factor
of considerable value, but some allowance must be made even for
that constant. Kebler’s modified assay process is as follows —
Place 20 C.c. of Stpiibb’s alkaline potassium iodide solution in a flask ,
add 10 C.c. of 1 to 2 per cent, aqueous solution of acetone and
the excess of sodium hypochlorite solution (about 4 normal), then
close the flask and shake. Next acidify with hydrochloric acid, add
the excess of decinormal sodium thiosulphate solution, and after
allowing to stand a few minutes, add starch indicator and re-titrate
the excess of sodium thiosulphate. The relation of the sodium hypo¬
chlorite solution to the sodium thiosulphate solution being known,
the percentage of acetone can readily be calculated. Thus 10 C.c.
of acetone solution containing 1 Gm. of the solution to be analysed
required 14-57 C.c. of Nx0'806 sodium hypochlorite solution,
which formed 14 '57 C.c. of iodine solution of same strength, or
14-57 x 0-806 x 0-1265 x 0-07612 , . . „
■ - — r - . ■ — - = amt. of acetone = 11-307 p.c.
1 Gm. of solution
The method is represented to yield satisfactory results for ordinary
work, the difficulty that lies in the end reaction being overcome by
having present a larger excess of the active agent to bring about
the complete reaction. — Am. Journ. Pliarm., lxix., 65.
Vop. LVIII, (Fourth Series, Yog IV. ). No. 1392,
The part played physiologically by the
Castoreum castor pouches is not yet clearly established,
du but it is generally accepted that they consti-
Gardon. tute part of the reproductive organs of the
beaver, and, as J. Gal points out, their weight
and the nature of their contents may therefore be expected to
vary according to the condition of the animal at the time it is
killed. He gives the formula, p = ( P — 6) 14, as probably repre¬
senting the relation of the weight of the fresh pouches, p, to that
of the animal, P, and quotes the following figures in support of it
No.
Animal captured.
Weight of animal.
Weight of fresh pouches.
1 . . . .
March 24, 1895.
11 kilos.
37 grammes.
2
July 12, 1895.
15 „
135
3 ....
October S, 1895.
7 ,,
13
4 ....
November 13, 1S95.
22 „
215
0 ....
October 27, 1896.
12 „
84
The fresh castoreum, weighing 16 '3 Gm., furnished by the fifth
specimen, was yellowish white, of characteristic odour, and had a
density of 0-85. It contained 4-3 per cent, of albuminoid sub¬
stances, and yields 0 '25 per cent, of ash.
Results of Analysis.
Loss at 100° .
Extracted by ether .
,, ,, alcohol ....
„ water .
,, „ acetic acid
Residue .
7-9
SS-4
0-8
o-i
o-t>
2 -2
ioo-o
The figures previously obtained by Lehmann for German, Russian
and -Canadian castoreum respectively, were : —
For the ether extract . 7 -4 2-5 S"2
,, ,, alcoholic ,, . 69-7 64‘3 41-3
but the marked differences between those and Gal’s figures is
probably due to the age of the products examined and, possibly,
to a total alteration in the nature of the secretion. The presence
of castorine and carbolic acid was not indicated in the fresh
specimen, though the Gardon beavers feed on willow bark.—
Comptes rendus, exxiv. , 246.
Crude commercial cumarin may be purified
Purification by repeated crystallisation from alcohol, or by
Of the following process, describedbyE. Claassen : —
Cumarin. The cumarin is placed in a capacious copper
distilling vessel or a good Bohemian flask,
petroleum spirit of low specific gravity is added, and after the still
has been connected with a condenser, the liquid is heated to boil¬
ing point and kept boiling for five or ten minutes. The still having
been removed from the source of heat, the liquid is poured in a
warm bottle, and on cooling, crystals of cumarin separate. The
crude cumarin is again treated with petroleum spirit, and the pro¬
cess repeated until it is exhausted. Any cumarin remaining in
solution in the spirit may be removed by shaking out with 5 per
cent, sodium hydrate solution, and subsequently precipitating
with hydrochloric acid. — Pliarm. Review', xv., 28.
P. Regnard and T. Schloesing have examined
Argon the gases obtained from a litre of blood,
in the and found that they contained 20 -4 C.c. of
Blood. nitrogen and argon, the latter gas accounting
for 0"419 C.c. of the mixture. In addition to
satisfying themselves that argon is dissolved in the blood, they
state that if there is an increase in the amount of nitrogen present
there will also be an increase in the amount of argon. — Comptes
rendus, exxiv., 302.
162
PHARMACEUTICAL JOURNAL.
[Fee. 27, 1897.
This plant belongs to the natural order
Monsonia Geraniacese, and to the same section as
Ovata. Geranium. It might therefore be expected to
• possess astringent properties, like those of
Geranium maculatum, the alum root of the United States, and it is
interesting to note that a tincture of Monsonia ovata , prepared with
rectified spirit (2£ ozs. to the pint), has been used with very great
success in the treatment of dysentery by J. Maberly, M.R.C.S., who
publishes a long record of cases that should go far to prove the
mxlicinal efficacy of this little known drug. It is an annual
plant, growing in the Yaal River district and probably
elsewhere in South Africa. It must be collected in January or
February, and seeds have been brought to England in the hope that
the plant maybe successfully raised here. — Lancet, February 6, 368.
W. F. Lowe has recently examined oysters
CoppeP containing copper in considerable quantity, a
in single oyster yielding 0‘04 Gm. of the metal.
OystePS. Some of the oysters were light blue in colour
and others dark olive-green, copper being
found in both. They were obtained from the Mumbles, near
Swansea. Professor W. A. Herdman, Avriting on the same subject,
quotes results obtained by Dr. Charles Kohn, who has determined
the amounts of both copper and iron present in various kinds of
oysters, by electrolytic methods. The green Marennes oyster con¬
tained about 0'4 Mgm. (0'006 grain) of copper, and that is thought
by Professor Herdman to be the normal amount present in all
oysters, white or green, and due to the hsemocyanin of the blood.
Dr. Thorpe, hoAvever, finds that the green Falmouth oysters each
contain, on the average, 0'023 grain of copper, which falls to the
normal amount (O’OOG grain) on re-laying in another locality. —
Mature, lv,, 366.
A modification of Saul’s method of sterilising
Sterilisation catgut is advocated by R. C. Larrabee, who
Of summarises the process as follows : — Wind the
Catgut. gut in a single layer on pieces of large glass
tubing, then place the latter in a tightly-
stop ered flask, fitted with a condenser consisting of a glass tube
at least five feet long and penetrating the cork. Use Saul’s
solution — absolute alcohol, 850 ; carbolic acid, 50 ; water, 100 — and
boil for forty-five minutes on a water-bath. For the largest sizes
of gut an hour is safer, and for the smallest half an hour will
suffice. Finally, remove the condenser, and close the flask with a
sterilised stopper, leaving the sterilised catgut in the solution used.
Or, the solution may be poured off, and a sterilised cotton stopper
inserted, the catgut then being preserved dry. — Boston Med, and
Sunj. Journ,, cxxxvi., 86.
Hesse found that cholera bacilli undergo
Micro organisms deterioration in raw milk, and when kept at
in a temperature of 37° C. are entirely destroyed
Milk. within twenty-two hours. Caro and Schotte.
lins, on the other hand, showed that anthrax
bacilli flourish abundantly in milk and fully maintain their viru¬
lence, and the last-named obseiwer has more recently observed that
diphtheria bacilli find an exceptionally satisfactory material for
growth and multiplication in fresh milk, though in sterilised milk
their growth is less marked. — Cent. f. Baht., and Nature, lv., 301.
T. Paul and B. Kronig find that the differ -
Bacteria and ent salts of a poisonous metal, such as mercury,
Chemical are not equally deadly to the spores of the
Reagents. anthrax bacillus, those which are electrolyti-
cally dissociated to the greatest extent being
most active under otherwise similar conditions. Thus, a solution
of mercuric chloride contains many more mercury ions that one
of mercuric cyanide of the same concentration, and is correspond¬
ingly more deadly, but the addition of sodium chloride to the first
solution diminishes the number of mercury ions, and causes a
marked loss of bactericidal power. The addition of salt to in¬
crease the solubility of mercuric chloride is therefore the reverse
of advantageous in preparing antiseptic solutions. Silver salts
yield similar results, the nitrate, chlorate, etc., which are dis¬
sociated into their ions to a considerable and approximately
equal extent in aqueous solution, having nearly the
same bactericidal action, while the addition of sodium
thiosulphate or potassium cyanide, with which the silver
ions combine to form complex ions, practically destroy the
bactericidal power altogether. This power, in the case of solutions
of bases or acids, depends, on the Avhole, on the strength of the
base or acid — that is, on its degree of electrolytic dissociation.
Silver nitrate exerts its maximum power when dissolved in 50 per
cent, alcohol, but in the case of mercuric chloride the maximum
occurs at 25 per cent. Solutions of either salt in absolute alcohol
are practically without effect on anthrax spores. — Zeit. f. phys,
Chem., through Nature, lv., 328.
M. B. Renault has long worked at the indi-
FoSSil cations of bacteria found in geological strata,
BaetePia. and now publishes the general result of his
observations in a paper illustrated with a large
number of drawings. As might be expected from their simple
structure, bacteria appear to ha\re been co-eval with the first appear¬
ance of organic life on the earth, the coccoid form being apparently
earlier than the bacillar. Indications of their presence are found
in bone, teeth, scales, and coprolites, as well as abundantly in
vegetable tissues, the spores and sporanges of ferns appearing to
have been especially subject to their attacks. The species are, as
a rule, distinct from those at present in existence. — Ann. des
Sciences Naturelles ( Botanique), 1896, p. 275.
Dr. V. Peglion describes_in Malpighia (1896,
Bacterial p. 556) a disease which attacks the stem of the
Diseases Of hemp, causing disintegration of the tissues. It
Plants. appears to be produced by an organism of the
nature of a bacillus embedded in mucilage, and
closely resembling B. cuboniana, a parasite of the mulberry. In
Bulletin, No. 12, for 1896, of the Division of Vegetable Physiology
of the U.S. Department of Agriculture, Mr. E. F. Smith states
that several species of Solanaceae— the potato, the tomato, and
the egg-plant, Solanum melongena — are attacked by a disease
which he calls “brown-rot,” due to a hitherto undescribed pai’asite,
which he names Bacillus Solanacearum. It closely resembles B.
tracheiphilus and the form known as “Kramer’s bacillus,” but
differs in several characters from both. In the Revue Mycologique
for 1896, M. E. Roze has described several bacteria which cause
diseases in the cultivated potato, viz., Micrococcus nuclei, M.
imperatoris, M. pellwcidus, always found associated with the
“scab,” M. albidus, and M. flavidus.
The very important discovery in the mode of
Fertilisation . impregnation in some Gymnosperms made by
in the two Japanese botanists, Professor S. Ikeno and
Gymnosperms. Dr. S. Hirase, which was recently referred to in
our pages, supplies a most interesting link be¬
tween this section of Phanerogams and the higher Cryptogams. Dr.
Hirase (Botanische s Gentralblatt, lxix., 1897, p. 33) has discovered
that in Ginkgo biloba (Salisburia adiantifolia ) impregnation is
effected by antherozoids formed within the pollen-tube. The tAvo
nuclei resulting from the final division of the generative nucleus of
the pollen-tube are converted, before entering the oosphere, into
motile antherozoids, resembling those of the higher Cryptogams,
Feb. 2 7, 1897.]
PHARMACEUTICAL JOURNAL.
163
but differing somewhat in form. They are ellipsoidal, 8‘2/.t long
by 49/j broad, and contain in the centre a nucleus,
entirely surrounded by cytoplasm. The main body con¬
sists of a head composed of three spiral coils, and a
slender tail ; to the former are attached numerous cilia. As soon
as the antherozoids have escaped through the apex of the pollen-
tube, they enter the oosphere with a rapid twisting motion.
Attraction spheres were observed accompanying the final division
of the pollen-tube nucleus. Professor Ikeno [Bot. Centrally. , lxix. ,
p. 1) has made a similar observation respecting the mode of
impregnation in another Gymnosperm, Cycas revoluta. The
antherozoids are here somewhat larger than in Ginkgo ; the main
body is composed of four coils, to which are attached a large
number of cilia ; but the swarming motion was not actually
detected ; the nucleus is surrounded by cytoplasm. They are found
in pairs in the extremity of the pollen-tube, and result from the bi¬
partition of the generative nucleus. Professor Ikeno states that the
structure of the male and female organs in Ginkgo biloba and Cycas
revoluta at the time of impregnation differs from that observed in
any other Gymnosperm in this respect ; that while, in the latter,
the pollen-tube penetrates deeply into the archegone, in the two
species under discussion it never reaches the archegone itself, but
remains, at the time of impregnation, at some considerable
distance from it. It would therefore be impossible for the pollen-
tube-nuclei to impregnate the oosphere without being previously
transformed into motile antherozoids. Fertilisation is then
rendered possible by the copious excretion of a watery fluid by
the archegone at the time of impregnation. Further details of
this most interesting discovery are promised by both observers.
Mr. J. L. Williams records, in the Journal of
Bees Botany (1897, p. 8), the singular effect pro-
Intoxieated by duced on certain humble bees by the honey
Honey. of some flowers with a very crowded capitular
inflorescence belonging to the order} Com- .
posit ai and Dipsacacete, especially Centaurea scabiosa, Carduus
nutans , and Scabiosa succisa. The phenomena produced on the
bees were those of intoxication, raising the legs convulsively in
the air, turning on their backs, and rolling about helplessly. In
so doing, their bodies became thickly covered with pollen, to the
promotion of the pollination of the flowers in question. As a
rule the bees rapidly recovered from the intoxicating effects, and
were eager to renew the experiment ; but in one instance the
insect, which had been shut up all night in a vasculum with
flower-heads of Centaurea scabiosa, showed, the next morning, the
greatest aversion to being placed again in the way of temptation.
The species which showed the greatest tendency to succumb to
temptation was the neuter of Bombus lapidarius.
Observations made on a variety of flowers —
HOW FlowePS Dahlia variabilis (single), (Enothera biennis,
Attract Lobelia Erinus, Delphinium Ajacis, Ipomaza
Insects. purpurea, Centaurea cyanus, Digitalis purpurea
—have led Professor F. Plateau to dissent from
Darwin’s conclusion that the chief attraction of insect# to flowers
is in their bright colour. In the case of the dahlia and other Com¬
posite, the removal of the conspicuous ray-florets had very little
effect in diminishing the number of insects which visited them ;
these flowers cannot, therefore, play the part of signals cr banners
assigned to them by Darwin. The result was the same in other
flowers when the conspicuous part of the corolla was removed.
Covering up the flower with leaves also had but little hindering
effect on the visits of insects, which must be attracted to the
flowers chiefly by some other sense, probably that of smell. — Bull.
Acad. B. Sciences Belgique, 1895 and 1896.
According to C. Wehmer, the fungus which
Rotting most commonly causes the rotting of fruits
Of is Penicillium glaucum. In apples and pears
Fruits. this is accompanied by Mucor pyriformis,
and in the case of medlars the latter is much
the most common fungus. In lemons, oranges, and other tropical
and sub-tropical fruits, P. glaucum is associated with two other
closely allied species, P. itaUcum and olivaceum. In plums Mucor
racemosus was also observed. In grapes Penicillium glaucum and
Botrytis cinerea are the most common fungi. It is the latter
species which forms the grey tufts on walnuts. — Beitrdge zur
Kenntniss einheimischer Pilze, 1896.
Mr. G. Murray records some remarkable
Reproduction observations on the mode of propagation of
Of Marine certain pelagic diatoms collected off the coast
Diatoms. of Scotland, chiefly belonging to the genera
Biddulphia, Coscinodiscus, and Choitoceros. In
Biddulphia mobUiensis “ cysts ” were observed within the parent
cell, with only slightly silicified membrane, and destitute of the
characteristic spines. These cysts appear to have the power of
dividing and multiplying before assuming the characteristic parent
form. A similar phenomenon was observed in Coscinodiscus
concinnus, but in this species the protoplasm divides before the pro¬
duction of the “cysts,” two of which were found within the same
parent frustule, differing from one another in form and in the
width of the girdle-zone. It is not uncommon to find the young
colonies of Coscinodiscus in “packets” of eight or sixteen; this
being apparently the result of further binary division within the
frustules, which are found accompanying them in an empty state.
The membranes of these young colonies are only very slightly
silicified, or not at all ; and they are, therefore, capable of increase
ing in size. A similar formation of “packets ” of eight or sixteen
young individuals within the parent frustule was observed in
several species of Chcetoeeros. — Proc. Royal Society of Edinburgh ,
1896, p. 207.
Hen’ J. Griiss states that when barley gen
Germination minates the solution of the celhwalls of the
Of endosperm commences in the neighbourhood of
Barley. the seutellum, and advances thence towards the
apex of the grain, most actively in the outer4
part ; but there is a small portion of the apex which usually remains
intact. The cell-walls are not dissolved, but corroded. Congo-
red stains intact walls an intense red, while those that have beerl
affected assume only a slight light-red tint. The starch-grains are
attacked only after the corrosion of the cell- wall, and first in the
neighbourhood of the seutellum. Diastase may be produced spon ¬
taneously in the endosperm of seeds that have not germinated)
and from which the embryo has been removed. —Wochenschrift fiii‘
Brauerei, 1896.
According to Professor A. Hansgirg, flowers
Protection may be classified under four types as regards
Of Pollen the mode of protection of the pollen against
from Rain. rain, viz: — (1) Flowers which close their
perianth in rainy weather, so as to prevent the
entrance of rain drops, without any change in the position of the
flower ; (2) flowers with erect flower-stalk, which curves in wet
weather so as to alter the position of the opening of the corolla and
prevent the access of rain to the pollen and nectar ; (3) flowers in
which the same purpose is served by the curving of the stalk of
the entire inflorescence ; (4) flowers which are erect and open in
fine weather) but during rain both close their perianth and at the
same time protect the pollen by a curving of the flower-stalk. ■—*
0 ester reichische Bot. Zeitschrift, 1896, p. 357.
164
PHARMACEUTICAL JOURNAL.
[Feb. 27, 1897
TBE PLOUGH COURT PHARMACY.
In the account recently published of the old firm of Godfrey
— tracing the origin of the term “ chemist and druggist ’ in its
present application— incidental mention was made of some other
important pharmaceutical establishments that were in existence
about the middle of the eighteenth century, and, among them, the
one situated in Plough Court, Lombard Street, ha^, for several
reasons, especial historic interest. The house in which the business
was formerly carried on, from about 1730 until 1873, was reputed to
have been, at an earlier period, the birthplace of the poet Alexander
Pope; it has been a very important centre, from which the great
social influences of the Society of Friends have been exercised ; one
of the proprietors of the business was the founder of chemical
works which probably rank among the oldest in the Kingdom
and, at a later date, another proprietor became the first President
of the Pharmaceutical Society.
The old premises in Plough Court— represented by the accom¬
panying illustration — consisted of three houses, which were built on
the site formerly occupied by a house bearing the sign of the
Golden Fleece” and by the mansion of Sir Nicholas Raynton, both
of which were destroyed by the great fire in 1666. From documents
in the possession of the Haberdashers’ Company, the house No. 2
appears to have been partly built and first occupied, soon after that
time, by Nathaniel Pope, citizen and salter, who there carried on
the business of a linen draper : it subsequently passed into the
hands of several members of a family named Osgood, who were
engaged in the same line of business.
The first pharmaceutical occupant of the premises in Plough
Court was Silvanus BevaD, a member of the Society of Friends, who
had previously carried on business as an apothecary in Cheapside.
The date of his removal to Plough Court is uncertain, but the entry
in Kent’s London Directory, published in 1736:
“Sylvanus and Timothy Bevan, Apothecaries, Lombard Street”
shows that he was then located there with his brother and partner,
Timothy Bevan. Their admission to the freedom of the Society of
Apothecaries is recorded at Apothecaries Hall as follows : —
1715. July 5th —“Silvanus Bevan, Apprentice of Thomas Mayleigh,
having Eerved 7 years and paid a fine of £6 9s for ye remainder of his
time acco dinar to ye order of Court of A'sist’., was Examined,
approved, sworne, and made free.”
173!. 6th Apri\ — “ Timothy Bavin hiving paid a fine of £25 and 40’.
to the Card in, wis puriuint to an or ter of last C uirfc of Assists.,
examine!, approved, aid sworn, and made free by Redemption.”
The arms of the Society of Apothecaries were displayed in the shop
window on a pane cf glass which has been p eserved as a relic of
the oil pi a^rn’cy.
Apothecaries were then the only persons having a recognised
qualification to practise pharmacy as freemen of the Company in¬
corporated under Royal Charter by James the First, in 1617, as the
Society of the Art and Mystery of Pharmacopolites of the City of Lon¬
don. The conditions on which that qualification was obtainable
were service of an apprenticeship of not less than seven years to
an apothecary or the payment of a fine, and, in either case the
pissing of gn examination as to knowledge, skill, and science in
the art. The Society of Apothecaries was empowered to regulate
the practice of pharmacy and its charter provided that no un¬
qualified person should keep an apothecary’s shop or practice “ the
faculty of an apothecary” in London, or within seven miles
around the city. But even within those limits the Society’s
jurisdiction was imperfectly enforced, for many persons without
the qualification kept shops as druggists for the sale of drugs,
pharmaceutical preparations and dispensing physicians’ prescrip¬
tions, while others engaged in similar business described themselves
as “ cbymists.” The extent of the competition to which apothe-
Feb. 27, 1897J
PHARMACEUTICAL JOURNAL*
caiies were thus subjected may be inferred from the fact that;
shortly after the Plough Court establishment was founded there
were, according to the London Directory, only nine apothecaries’
shops between Holborn and Aldgate, while there were, within tfce
same area, no less than thirty-nine druggists’ shops, and two
chymists. Eighteen of these shops were within half a mile of
Plough Court and three of them were in Lombard Street.
At that time the business of an apothecary was not confined to the;
making of pharmaceutical preparations and the dispensing of medi¬
cines ; it also included the prescribing of medicine and the medical
practice carried on by apothecaries without recognised medical
qualification, had been, for a very long time, as much a source of
discord as the druggists’ competition was then becoming. In both
respects a vigorous contest wa3 being carried on— with regular
medical practitioners who objected that apothecaries encroached
upon theirprivileges— and also with druggists, who were denounced
by the apothecaries as being incompetent to perform the functions
of a pharmacist. Recriminations on these and other grounds were
freely indulged in on ail sides without doing much more than
demonstrate the want of suitable regulation of the practice of
medicine and of the practice of pharmacy as professional occupations
requiring special knowledge and technical skill on the part of
those engaged in them. But while the apothecaries urged, in the
interests of the public, the desirability of a guarantee for the
competence of every person authorised to practise pharmacy, they
also sought, in their own interest, to extend the scope of their
medical practice.
Those were the conditions prevailing during the time that the
Plough Court Pharmacy was carried on by Silvanus and Timothy
Bevan, but there is no evidence that they took part in the struggle
going on. From the fact that their successors were not apothe¬
caries, but are described in the directories of the time either as
“ druggist ” or as “ chymist,” it may be inferred that the prevailing
tendency was for the business to develop in the purely pharma¬
ceutical direction.
The pharmacy cf the period when the Plough Court establishment
was founded had not advanced much beyond the primitive charac¬
ter represented in the earlier editions of the Pharmacopoeia of
the Royal College of Physicians in London. The medi¬
cines then in use were chiefly galenical preparations,
among which the species and electuaries, including diascor-
dium, mithridate, and theriaca, may be mentioned as charac¬
teristic. Contemporaiy writings show that, in connection
with the preparation of medicine, the utility of chemical knowledge
was beginning to be appreciated, but the only “ chymical medicines”
in the Pharmacopoeia of 1721 were a few preparations of iron, anti¬
mony and mercury, some salts and distilled products such as Spirits,
volatile and empyreumatic oils. The official list of materia medica
was very extended, 'comprising more than a thousand articles
derived from plants, more than a hundred of animal origin, and
nearly the same number of mineral origin. The Pharmacopoeia
of 1746 bears evidence of some improvements having been made,
though the general character of pharmacy remained unaltered.
Another circumstance characteristic of the period now referred to
was the large trade in medicinal ' specifics, some of which were
prepared after the prescriptions of physicians, as in the case of Dr-
Mead’s remedy for the bite of a mad dog and Sir Hans Sloane’s eye
salve, while others were made the subject of patents, like Dr. Bate¬
man’s pectoral drops and Dr James’ fever powder. The first patent
for a medicinal preparation— --sal oleosum volatile — was granted in
1711 to Timbth^ Bjfield. But proprietary medicines of a similar
kind were so numerous that in 1748 a list of more than two hundred
of them was published in the Gentleman' s Magazine , under the title
of “ Pharmacopoeia Empirica,” with the prices at which they were
sold, the names aud addresses of the proprietors and the ailments
they were said to cure, so that “persons who could not afford the
expense, or might not care to be governed by the advice of the
physician and apothecary, might know where to apply on occasion
for an appropriate remedy.”
The preparations included in that list were in very few instances
patented, but chiefly secret nostrums which were often freely adver¬
tised in newspapers by the proprietors— sometimes surgeons or
apothecaries— with the object of inducing patients to consult them
personally. The trade carried on in such articles became so exten¬
sive that in 1783 the Government considered them to be “ very
proper objects of taxation.” The Act of Parliament passed for that
purpose imposed an ad'valarsni stamp duty on such medicines, and
requ’red vendors to take out an annual licence unless they had served5 a
regular apprenticeship to a surgeon, apothecary, druggist of chcihllt.
Before passing from this stage in the history of the Plough Uourt
Pharmacy, some incidents may be mentioned which throw interesting
side-lights upon the manners of the time, as well as' the relation¬
ships and position held by the proprietors of the business. Both of
the first partners were twice married. Silvanus Bevan’s first 'wife
was Elizabeth, daughter cf Daniel Quare, citizen and clockmaker
of Exchange Alley. The marriage took place in 1715 at the Friends
Meeting-house in White Hart Court, Gracechurch Street, and was
attended by a great number of persons of rank, as well as relations
and friends, probably in consequence of Q rare being well
known as clockmaker to the Queen. William Penn is said tc
have been present on the occasion, and the marriage certificate bears
among other signatures that of Sarah, Duchess of Marlborough
The following account cf the ceremony is taken from a letter written
at the time by a lady who was present : “ Y° Prince and Princesse
and moust of jc quality was invited, and thay gave them some hopes
of honouring them with there company till y° night before, and
then they sent word j* thay could not come, r.or none cf yc quality-
which had places, becaues of ye Actt which obliges them to go into¬
ne meeting— but thare several of je quality yt had no places.
yc Dutchess of Marlbourow was thare and yc Lord Finch, }e Lady
Oartwrite, y° Yenetion Ambascior and his lady, and a lady that is
governess to ye young Princesses, hous name I have forgot, and
several other persons of distinction. Thay desired y* yc meeting
might be put cf till one of je clock, which was don.
“ Accordingly from thence we went to Skiner’s Hall, where we-
dined, they gave a very Splendid dinner as could b?, and y'c quality
was mightily pleased both with ye ceremony of ye mam ge and thare
entertainment, as to yc young cuple they came of very well. Ye
bridegroom spoke very hansomly and y® bride better than could be
expected before so great an ascembley. I had ye honour to wate or*
them home at night.”
Silvanus Bevan’s second wife was Martha, daughter of Gilbert
Healhcote, cf Culthorpe, Derby. He had no children who survived
him and, on retiring from the business, about 17G4, was succeeded
by bi3 brother.
Timothy Bevan married first Elizabeth, daughter of David Barclay,
and afterwards Hannah, daughter of Joseph Gurney and widow of
Nathaniel Springall, of Norwich. Of his three sons the eldest—
Silvanus— became a partner in the barking firm of Barclay, Bevan,
and Go. ; the second— Timothy Paul- -became his father’s partner,
and the youngest— Joseph Gurney Bevan— succeeded to the business
in Plough Court after the retirement of his father, about 1775,
and is described in the London directories of the time as “Druggist
and Chymist.”
Joseph Gurney Bevan possessed a vast influence in the councils
of the Society of Friends ; he was a man of great learning and very
166
PHARMACEUTICAL JOURNAL.
[Feb. 27, 1897
scrupulous in the discharge of obligations. While conducting the
Hough Court establishment he had one night a week to do duty as
Chief Constable ana he was extremely particular in fulfilling all
the disagreeable duties of the post, because he feared a substitute
might employ physical force in the discharge of his duty. On those
occasions supper was served at. an earlier hour and he u3ed to
attend at the station house clad in a huge white greatcoat and
furnished with classical works for midnight reading. He continued
to manage the Plough Court Pharmacy until 1794 when it passed into
the hands of Samuel Mildred, brother of a banker in an adjoining
Street.
Within the sixty-four years that had elapsed since the founda¬
tion of the Plough Court establishment, the druggists and
chemists in London had become nearly ten times as numerous as
apothecaries, who were for the moab part engaged in medical
practice and, with seme
few exceptions, had ceased
to be merely pharmacists.
Adam Smith, writing in
1775, spoke of the apothe¬
cary as being then “ the
physician to the poor at
all times, and to the rich
whenever the distress or
danger is not very great.”
But for many years after¬
wards the Society cf
Apothecaries was without
any power of conferring
medical qualification and
the power of regulating
the practice of pharmacy
vested in it by the charter
of 1617, had been practi¬
cally lost, for long before
the end of the eighteenth
century, the oompoundirg
sf medicine and the dis¬
pensing of physicians’ pre¬
scriptions was generally
carried out by druggists
and pharmacists. They
had no recognised quali¬
fication and the only
available means of phar¬
maceutical education was
apprenticeship of about
seven years’ duration, com¬
menced at the age of
fourteen or fifteen, with a premium of two or three hundred pounds.
The few regularly qualified apothecaries who, during the latter part
of the eighteenth century, adhered exclusively to the practice of
pharmacy were, frcm the nature of their business, described as
diuggists or chemists and not by the term apothecary, which was
then understood to mean a practitioner of medicine. Thus the
earlier proprietors cf the Plough Court Pharmacy, Thomas Paytherus,
who founded the house of Savory and Moore in 1796, his successor,
John Savory, as well as Charles James Payne, afterwards
the second President of the Pharmaceutical Society, William
Randall, of Southampton and several others carried on business as
chemists and druggists, though they were regularly qualified apothe¬
caries. V arlous other changes had also taken place in connection with
*n:dicine and pharmacy, as shown bythe ‘LcndonPharmacopoeia’of
1788. The number of officially recognised drugs had been very
much reduced, most of the complex alexipbarmic preparations
formerly in use had been excluded and many chemical products
had been brought into use as medicinal agents. With increased
simplicity of material and formulae a more systematic nomenclature
was adopted and the benefits arising from chemical inquiries were
being more fully acknowledged. Since the time of Robert Boyle, when
the dreams of the alchemists began to be replaced by a more rational
study of natural phenomena, chemistry had made great progress and,
on the Continent, many pharmacists had contributed to its advance.
Among the number Kunkel, Lemery, the brothers Geoffroy, Neu¬
mann, and Margraff had become especially distinguished by their
chemical researches, during the period when the phlogiston
theory was generally accepted and, subsequently, when that theory
was being superseded, Sohcele, Klaproth, Yauquelin and Proust
took a prominent position
among the founders of
modern chemistry. Up to
that time no British phar¬
macist had acquired simi¬
lar distinction ; but in the
first decades of the present
century the history of the
Plough Court Pharmacy
furnishes, in more than one
instance, demonstration of
the possibility of combin¬
ing the prosecution of
abstract scientific wo; k
with the ordinary business
occupations appertaining
to the ^practice of phar¬
macy.
During the period that
Joseph Gurney Bevan was
the head of the Plough
Court establishment, Wil¬
liam Allen, the son 'of a
silk manufacturer in Spital-
fields, was placed with
him in consequence of a
taste he had shown for
chemical and other pur¬
suits connected with medi¬
cine and in order to afford
him opportunity for study.
While in that position
he * attended various
courses of lectures de¬
livered at the medical schools and acquired a practical knowledge
of chemistry. He subsequently became a partner in the business
and, as its head for nearly fifty years, also occupied a distinguished
position a3 a scientific teacher and investigator, besides being a
leading promoter of many important philanthropic undertakings.
At an early age William Allen commenced the practice of keeping
a diary, in which important transactions were recorded with much
precision. Many of the entries in this diary furnish interesting
information concerning the Plough Court business and the various
other pursuits in which he was engaged throughout his life. The
first mention of Plough Court in the diary is in 1793. Before that
time, while young Allen was residing with his parents, several
entries showj that he was deeply interested in the movement
then commencing In regard to the abolition of the Slave
WILLIAM ALLEN,
Feb. 27, 1897.]
PHARMACEUTICAL JOURNAL.
Trade and in tfce efforts then being made by Wilberforce,
William Pitt, C. J. Fox, and Burke. At a later period
William Allen became actively associated with Wilberforce and
Thomas Clarkson in this work, as a member of the Committee of
the Society for the Abolition of the Slave Trade, originally formed
in 1783 by William Dillwyn, George Harrison, Samuel Hoare,
Thomas Knowles, M.D., John Lloyd, and Joseph Woods.
After taking up his residence at Plough Court, much time was
devoted to the study of chemistry and other scientific subjects,
attending lectures at Gay’s and St. Thomas’s Hospitals and the
meetings of scientific societies. In conjunction with several
friends, including Arthur Arch, Joseph Fox, Luke Howard, Henry
Lawson, W. H. Pepys, William Phillips, and Samuel Woods,
a society was formed for mutual improvement under the
name of the “ Askesian ” and meetings were held at
Plough Court twice every month during the winter season.
Astley Cooper, Dr. Babington, A. Tillocb, Joseph Woods, Jun., and
several others afterwards joined this Society, which continued for
some twenty years. The second meeting of the Society was in
March, 1796. A year before that time William Allen had entered
into partnership with Samuel Mildred, the business being carried on
under the style of Mildred and Allen, Druggists and passages in
the diary appear to show that a laboratory was established at
Plaistow for the manufacture of chemical products.
Towards the end of 1796, William Allen married Mary Hamilton,
and though her death, during the following year, was a severe afflic¬
tion, he was soon afterwards actively engaged with his friend
William Phillips in carrying out a previously formed project for the
amelioration of the state of the poor, which proved to be of very
great benefit for several years afterwards in relieving the distress
caused by the war, when “ there was a dismal scarcity of provision s
— bread fifteen pence the quartern loaf.”
During the next three years business anxieties interfered to some
extent with the prosecution of study and scientific work, but several
entries show that meanwhile great progress was being made in
carrying out chemical and physical experiments with his friend
Pepys, on their own account, as well as for Dr. Fordyce and others
About this time Richard Phillips, the son of a printer in Lom¬
bard Street, became a pupil of William Allen at Plough Court
and there acquired the knowledge of chemistry and pharmacy,
which he afterwards displayed as critic of the London
Pharmacopoeias of 1809 and 1815 and in various other capacities.
A younger pupil, William West, after leaving Plough Courb and
settling as a pharmacist at Leeds became an active member
of the Philosophical and Literary Society and, as its honorary
secretary, took part in the formation of the British Association for
the Advancement of Science in 1831. Both he and Richard
Phillips were, like William Allen himself, subsequently elected
Fellows of the Royal Society.
On the retirement of Samuel Mildred in 1797, Allen took into
partnership his friend, Luke Howard, who had previously been
in business for about two years as a retail chemist in Fleet Street
Luke Howard had served an apprenticeship to Oliver Sims, a druggist
at Stockport, and since then had been for some time engaged in the
establishment of a large' wholesale druggist in Bishopsgate Street,
probably the firm of Kirk, Hearons, and Bright. The style of the
firm then adopted was Allen and Howard, the Plough Court estab¬
lishment being under the management of William Allen, while the
laboratory at Plaistow was directed by Luke Howard with the
assistance of Joseph Jewel), who had been for some time pre-
\iously employed at Plough Court and had shown great capacity
for conducting chemical operations.
(To be continued.')
107
NOTES AND FORMULAE.
(Specially Compiled for the Pharmaceutical Journal. )
Mentholated Crayons.
Menthol and chloral hydrate, of each 1 part ; cacao butter,
2 parts ; spermaceti, 4 parts. Melt the last two ingredients, add
the chloral and the menthol, and run into a suitable mould. —
Pharm. Zeit ., xli. , 505.
Preparation of Bismuth Iodogallate.
Subnitrate of bismuth, 30 ‘4 grammes, dissolved in 100 grammes
of nitric acid, and to the solution 500 C.c. of warm water
is added. To this is added with constant agitation a clear solu¬
tion of 16 '6 grammes of potassium iodide and 1 8 '8 grammes of
gallic acid in 300 C.c. of distilled water. The precipitate
collected, washed with a saturated solution of gallic acid, and dried
— Journ. de Pharm. d’ Anvers, lii. , 326, after Nouv. Bern.
To Stain the Ringworm Fungus.
Adamson recommends the following method for permanently
staining trichophyton: — 1. Soak the hair in a 5 to 10 per cent, solu¬
tion of caustic potash for ten to thirty minutes on a slide. 2. Wash
in 15 per cent, alcohol in water. 3. Dry on slide, and in the case
of scales fix by passing through the flame. 4. Stain in aniline
gentian violet (made in the usual way, by adding a few drops of
saturated alcoholic solution of gentian violet to aniline water) fifteen
to sixty minutes. 5. One to five minutes in Gram’s iodine solution.
6. Decolorise in aniline oil two to three hours or longer. 7. Remove
superfluous aniline oil by blotting paper, and mount in Canada
balsam. — Clasg. Med. Journ., xlvi. , 236, after Brit. Journ. Derm.
Hasmatogen.
According to Hertel, ivhen fresh ox-blood, in the presence of a
trace of caustic soda solution, is shaken with freshly-precipitated
ferric hydrate, a trace, amounting to about 0 '02 per cent, of the
whole, is dissolved by the blood, aiyl remains in definite combina¬
tion with it. This preparation he calls hasmatogen Hertel. It is
essential that the blood should be as fresh as possible.- Pharm.
Zeit. fur Bus-s. , xxxv. , 500.
Caramel in Fluid Extracts.
According to El Monitor caramel, as a colouring agent in fluid
extracts, may be detected by adding an excess of solution of sub¬
acetate of lead, filtering, removing the lead from the filtrate with
dilute sulphuric acid, again filtering, when, if caramel bo present,
the clear liquid is brown ; otherwise it is nearly colourless.
Pharmacy of Iodol.
Iodol Collodion : Iodol, 1 ; ether, 5 ; collodion, 10 parts. For
covering open or suppurating wounds. Alcoholic Glycerole of Iodol :
Iodol, I; alcohol, 16; glycerin, 14 or 34 parts. Iodol Lanolin:
Iodol, 5 or 10 ; lanolin, 95 or 90 parts. Iodol Vaselin : Iodol, 1 to
2 parts; vaselin, 10 parts. Iodol Ether: Iodol, 10 to 20 parts;
ether, 20 to 80 parts. — Pharm. Central., xxxviii., 475,
Test for Vanillin.
To a solution supposed to contain vanillin add a few drops of a
1 per cent, solution of ferrous sulphate, and then bromine water,
drop by drop. Vanillin gives a bluish-green colour, turning yellow
after a time. — II Bollettino Chimico-Farmaceutico.
168
PHARMACEUTICAL JOURNAL.
[Feb 27, 1S97
THE CASE FOR THE P.A.T.A.
BY WILLIAM JOHNSTON.
Pharmaceutical Chemist and Assistant Secretary to the P.A.T.A.
Amongst the reasons for the existence of the Proprietary Articles
Trade Association, perhaps the first in order is the fact that there
is no other convenient rallying point for the retailers of this
country to meet and take counsel together for the protection
of their everyday trade interests. Some of our trade interests,
and all of our educational and scientific interests are well looked
after “ in another place,” but it is difficult to make one machine do
everything, and impossible to make it do everything well. In
particular, some agency should attend to- the needs of that
despised, though not necessarily despicable part of our business —
the trade in proprietary articles, and it is a fact that there is no
agency in Great Britain, other than the Proprietary Articles Trade
Association, both willing and able to do that, with any chance of
success. Except in the better class of pharmacies, the stocking of a
large number of proprietary articles is an absolute necessity — not
f ir their own sakes solely or intrinsically, but for what the sale
leads up to. Supposing the average chemist — the kind composing
the bulk of the craft — were to say, “I will charge full price for
-al 1 these articles,” in most neighbourhoods he would simply drive
bis customers into “bottom price” shops. Or, supposing he
adopted the drastic method of “boycotting” the whole of
them the effect would be much the same. A chemist
who adopts such methods may be a very brave man, but
it would be a ruinous policy to adopt in most cases. I know very
well he could persuade his customers to have his own preparation
twenty times in the hundred, but how about the other 80 per
cent.? It won’t do to drive them to the shop of the “cutter,”
because when they go there they will be tempted to buy other
things which the chemist would like to supply.
Some retailers inform me that they now refuse to stock a “ few ”
of the worst specimens of cut goods. Almost all agree, however,
that it would not be possible to treat everything like that with im¬
punity. This being the case, unless a chemist has a good dis¬
pensing connection in a wealthy neighbourhood, or has a private
income, he is practically compelled to compete with the stores by
cutting. And how unsatisfactory that is ! How vexing and
galling to sell bottle after bottle of stuff at a halfpenny profit or
no profit at all ! Truly a- protective association was needed, and
without doubt the existence of the P.A.T.A. is justified, no less by
the facts enumerated than by the measure of success it has already
achieved. Meantime those who are working for the movement
are straining every nerve to haiten it forward, and to get more
important articles on the protected list.
Another reason for the existence of the Association is the con¬
sideration that if the prices f.of advertised proprietaries were
levelled up to one uniform rate the main body of chemists
would be more likely to get their fair share of the trade in drugs.
Do away with the object lesson of cut “patents,” etc., and you
!es en the undue influence which capitalists and others have exer-
• cis :d on the public mind through the pernicious system.
Objections to joining the Association have been raised in the
columns of the J ournal and at meetings. The more important of
these may be replied to in order.
(a) “ I do not believe in trades unionism.” When analysed, that
resolves itself into, “ I do not believe in unity of action or in com¬
bination, either for defence or attack but what helpless, disjointed
units we should be in national and municipal life if that principle
were applied all round. Why should the reasonable grievances
of traders be excluded from benefit that may accrue by com¬
bination ? For my part I can see nothing wrong and everything
right in concerted action against the big cutters, who care for
no interests save their own.
(b) “Ido not approve of any artificial forcing up of prices.”
This is very plausible, but the P.A.T.A. only aims at preventing
the cutters from forcing prices down below those fixed by the
owners of protected articles and duly advertised to consumers.
(c) “ You cannot profitably interfere with the laws of supply and
demand.” The laws of supply and demand are in many instances
brutally cruel in their operation and, whenever they are so, they
certainly should be resisted. In the present instance it is both
desirable and possible to resist.
( d ) “I sell very few patents. I do not care. I am not going to
join. Jt is too late in the day.” But it is not too late. There
is nothing to prevent proprietors from completely altering the
face of tl.jngs if they choose ; many of them are simply waiting to
be convinced that the trade really wants protection, and there¬
fore it should be apparent that it is our duty to help in con-
vincing them.
(e) “ I do not want to encourage quackery. I am not going to
join.” Now, even if supporting the P.A.T.A. meant “encouraging
quackery,” this would still be a very pedantic position to take up ;
but the P.A.T.A. does not promote quackery. When traders
band themselves together to obtain reasonable profits on things
they are virtually obliged to deal in, it does not follow that they
are believers in and promoters of the use of such things, but only
that they are sensible business men. Besides, proprietary
medicines are not the only articles touched by the Association.
The list includes foods and toilet articles ; whilst it is quite likely
it will include photographic articles before long. Candidly, I
think chemists and druggists ought not to be quite so ready to cry
“quack.” Granted that some advertised nostrums pretend to
cure almost every ailment under the sun with unblushing effron¬
tery, there yet remain a great many that are really good in their
way for simple ailments. Most of them were originated by phar¬
macists, though in many instances they may now be owned by out¬
siders. And how about our own preparations ? We do not con¬
sider them quack nostrums, but I fear they would be so labelled (I
mean the secret, advertised ones) by the majority of medical men.
(/) “I do not want protection. I protect myself by selling my
own things on every possible occasion*” This is a specimen of
another class of irreconcilables who will hear of no compromise
whatever. He is a stalwart, stiff-backed individual, and is entitled
to a certain amount of respect, yet I must differ from him about
the wisdom of his policy. W e will assume that he has thoroughly
mastered the art of substitution, and can sell without offending ;
there is still this difficulty to contend with — there are hundreds of
times when he has no chance to substitute, either through pressure
of business or persistence of customer. What an immense advan¬
tage to the retailer to have a guaranteed profit to fall back upon in
such cases ! There is no valid reason why we should neglect to
reap some benefit from the immense amount of advertising that
is constantly being carried on at no cost to us. This class of
objectors is also a very small one. Eight out of ten substi tutors
stay their hand when an article goes on the protected list.
They reason that if a proprietor goes out of way to guarantee a
real profit, he is entitled to- a considerable share of retail good¬
will, and they are thus able to make a harmonious blend of self-
interest, esprit de corps, and fair play.
(g) “ When I have bought anything and paid for it, I have a
right to do as I like with it, without interference from any associa¬
tion.” Quite so, always provided you bought it without any con¬
ditions attached to the purchase. That makes all the difference.
When a protected article is purchased from a wholesale
house by a retailer, the latter knows very well that the
makers insist on certain anti-cutting conditions, and that those
conditions have to be agreed to equally by the retail trade and
by the wholesaler. There is no hardship on the retailer in that,
because he need not buy the goods unless he likes.
(h) “ I will not join yet, because you have got so few really big
things on the list.” This is not a very valid reason for
holding aloof, and the situation in that particular respect
would be laughable did it not exhibit such a painful want
of common sense. On the one hand the big manufacturer says,
“ I will not protect till I see if the retailers join this P.A.T.A. in
anything like numbers.” On the other the stand-off retailer says,
“ I will not join till the big manufacturer does.” And there they
would stand staring each other in the face in what would be a
stupid deadlock were it not for the action of more enterprising
individuals on both sides. If the retail side will but continue to
lead the way the manufacturers (who, after all, have the most at
stake) will follow. Several have already said so. I will not go so far
as to say that it is mean to hold aloof and let others bear all the work
and expense, but at the same time it cannot be called a generous
thing to reap an undoubted advantage, and not stir one little
finger in return.
(i) “ I object to the raising of the wholesale prices of some of the
protected things. I charge full price for everything, so I now get
less profit rather than more.” This is the only argument
against us in which there is any body or substance. It is not in
any degree a fatal objection and those who raise this objection
should remember that the P.A.T.A. is not responsible for the rise
in prices. Unfortunately many retailers are urging manufacturers
on to raise their wholesale prices ; but though the aim is right,
the method is wrong and not for one moment to be compared
with protection, for general advisability.
Feb. 27, 1897]
PHARMACEUTICAL JOURNAL.
169
THE CASE AGAINST THE P.A.T.A.
BY JOHN INGHAM,
Pharmaceutical Chemist.
The proverb which bids us take the bull by the horns, has its
opposite in that which advises us to let sleeping dogs lie, or in
that which warns us of the folly of stirring up a hornet’s nest.
They all contain a moral of very wide application. I think it may
be opportunely applied to the policy of the P.A.T.A., especially
as enunciated in the second clause of its rides. The object of the
rule is thus expressed ‘ ‘ to take such steps as the Association may
be advised are legal to deal with extreme cutting of prices, to
give advice and to render assistance, to its members in preventing
substitution.” That object is very legitimate and worthy of com¬
mendation. The advantages aimed at by the Association have
been so wTell put forth and explained by Mr. Glyn- Jones, that few
can come to any other conclusion than that they are most desirable.
The evil it wishes to combat is rampant and demoralising in the
highest degree to the best interests of pharmacy.
Freely admitting that the sale of proprietary articles forms a
large and important part of the chemist’s business and that it
must necessarily remain so, I have never been enlightened enough
to think it should be made a prominent part, nor do I see the
wisdom of selling proprietary articles at or about cost price.
I hold a strong opinion that a very large number of them might
be given up without pecuniary loss to the pharmacist, who has
boundless resources to fill up these blanks if he be a master in his
art. It is not, therefore, with the object of the Association that
I am here concerned, but rather with the wisdom and the ethics
of the modus operandi.
The work so far done seems to concentrate itself on the one
object of compelling manufacturers of proprietary articles to
■compel retail vendors to do what their common sense should in¬
duce them to do for their own advantage as well as for the general
good of their craft, viz. , to sell at a reasonable profit. That
method is unconstitutional and altogether opposed to the per¬
manent principles of free trade. It is far too late to think of
monopolising the sale of the goods in question, and druggists
cannot expect any special favour over that part of their business.
So far as I can see no pecuniary advantage has yet accrued to
anyone from the Association’s tactics. Here is the point when one
begins to question the wisdom or otherwise of attempting any¬
thing on these lines. The agitation is simply bringing more and
mere to the front that part of the chemist’s business which should
be kept in the background. It is really stirring up a hornet’s nest
and waking the sleeping dogs. It is rousing to further action and
more strenuous opposition the latent resources of the extreme
cutters, whether they be company stores or qualified chemists.
It has been well said that the very existence of cutters depends
upon their under-selling. That is only part of the truth, for it
is self-evident that their very ability to sell at all depends upon
the traitors in our own camp. The under-selling of cutters will
not be stopped by the withdrawal of a few dozen patent medicines
from their lists, for it is not from that class of goods they make
their chief profits. However, allowing for argument’s sake that
they come into line with the proprietors’ conditions and agree to
sell the restricted articles at a fixed price, what would be the
result ? It would make matters worse, for their profits being
enlarged, they would be increasing their chance of success, or
using the profits to reduce still further their charges for dispensing
and drugs. Not only is the method of attack unconstitutional,
but it has within itself the essence of weakness, and therefore of
failure, by reason of its impracticability. The attempt to bring
the greater part of 15,000 chemists to one mind on the subject is
Utopian in the highest degree. The success that has attended
the Association so far as numbers are concerned is greater than
might have been expected : but when a certain point has been
reached in business or any movement of a voluntary nature,
we all know how difficult and slow a further advance is. The
P.A.T.A. will be no exception to the rule. The great object
of proprietors is to have their goods distributed by as many
retailers as possible : it matters not to them whether the distri¬
butors be chemists, grocers, or booksellers. They want distri¬
butors everywhere so that the public may find them close at hand
and obtain their articles in the remotest village with the least
possible trouble. With this end in view the makers have spent
immense sums in advertisements. There are many reasons why
the chemists have been and still are their best agents, but they are
not essential. Those who, by lavish distribution of hand-bills
and prominent exhibition of goods, have increased their local
sales, must not forget that nearly every sale of a proprietary
medicine takes the place of some Pharmacopoeia preparation that
would have been more profitable.
Admitting for a moment that the coercive policy of the Associa¬
tion is successful, . that maybe every vendor and manufacturer-
joins it, would the result be any credit or advantage to chemists as
a body of educated men? Certainly not. If each side were
faithful to the agreement, proprietors would have such a whip-
hand over the trade that, by doubling the intensity of their
advertisements, the chemist would become more and more a dis¬
tributor of packed goods and proprietary articles. That policy
will not succeed. Two or three thousand may join the Associa¬
tion, but they will never be able to induce a large percentage
of proprietors to boycot the bulk of the trade and all the other
channels through which their goods circulate. If they did so
they would find a large falling off in their sales consequently,
one by one they would withdraw from the position and place
their articles upon the open market. The same will happen in
the retail section of the Association, for those wrho have made a
connection by extreme cutting will find many of their customers
cease to come to them when they are no longer cheaper than their
neighbours. They, too, would withdraw, and in the course of a
few years the society would collapse. The necessity of with¬
holding supplies from men who will not keep the agreement would
be a source of constant annoyance to wholesale houses, and the
difficulty of detecting transgressors would be insurmountable
without the employment of many paid detectives. I do not desire
to appear as an advocate for proprietors of specialties ; they
are well able to take care of themselves, but I wish to point out
that the attempt to coerce them to. enforce a minimum retail
price is unjust. It should be borne in mind that they have had
no part in bringing about the present condition of things. The
necessity for the agitation is due entirely to the folly of chemists
themselves. Proprietors, it is true, have in many cases taken
advantage of the position and said, if chemists are such fools as to
give their profits to the public, they might as well have more
themselves. Hence, the advance in the prices of so many articles.
The most chemists can legitimately ask for is that they shall con¬
tinue to advertise the retail price of their preparations,- and to
supply on terms which make it worth chemists while to stock and
sell them. If they will not do this the only sensible and honour¬
able .plan of cutting is to cut the articles altogether.
Extreme cutting is like many other evil things, and the least
publicity given to it the better. It is one of those phases in the
evolution of pharmacy that must have its day. The true remedy
for the present unsatisfactory state of affairs can only be found by
every pharmacist feeling that he is one of a corporate body whose
honour and dignity is tainted by every mean action of his own.
When amongst us there exists that sense of duty and obligation
to others which animated the founders of the Pharmaceutical
Society and enabled them to look with kindly eyes upon the affairs
of their neighbours as well as their own, when no qualified
chemist can be found who will sell his services to company
stores or cutting chemists, then we may begin to feel that the
desired object is near at hand.
In days gone by if a man opened a shop, he expected to
build up a business in a straightforward way by his own merits.
Now the boom of every new man is “Patent medicines at store
prices,” And an attempt to undersell all around him.
Is it for that young men are spending their money and giving
years to study for stiff examinations ? It should not be so, for I
am convinced that the true remedy for this and other trade abuses
lies not in regulations and interference of associations, whether
legal or otherwise, but entirely in our own hands.
“ Follow Light and do the Right,
For man can half control his doom."
Method of Determining Minute Quantities of Nitrites. — -
Zambelli recommends the following colorimetric method for
determining nitrites. A reagent is made by dissolving 2 grammes
of sulphanilic acid and 2 grammes of phenol in 50 C.c. of equal
parts of sulphuric acid and water. A measured quantity of the
solution to be tested is placed in a fiask, and 2 or 3 C.c. of the
above solution added. In ten to fifteen minutes the solution is
made just alkaline with ammonia ; if nitrous acid be present a
yellow coloration will be produced. This colour is matched by
repeating the reaction, using a standard solution of silver nitrite. —
Jown, §0C, Ohm. Ind., XV., 617, after Monit, Sckntif
170
PHARMACEUTICAL JOURNAL.
[Feb. 27, 1897.
PRACTICAL PH ARM ACOG RAPH Y.
STRUCTURAL CHARACTERISTICS OF SOME
IMPORTANT DRUGS.
ACONITI FOLIA.
Aconite Leaves. — Feuilles d’Aconit Napel. — Eturmhutkraut.
Macroscopic Characters. — The fresh leaves and flowering tops
of Aconitum napellus are collected from plants cultivated in Britain
when the flowers are beginning to expand, i.e., about the end
of May or the beginning of June. At this time, before the
formation of seeds, the part of the plant above ground is richest
in alkaloid, the leaves when dried containing about 0‘3 per
cent., and the flower-buds about 0'4 per cent. The plant
flowers earlier than other species of aconite, and is characterised
by the shallow or semicircular hood or upper sepal of the blue
calyx. The flowers are usually arranged in a simple raceme, but
during wet seasons a few lateral bi'anches are given off. These are
never incurved or distorted. The two lateral sepals are broadly
obovate and obtuse, and the lower two are elliptic-lanceolate and
obtuse. Two of the petals form hammer-shaped tubular nectaries
which are hidden in the helmet-shaped sepal, and normally there
are also three very small linear petals, distinguished from the pale
filaments of the numerous stamens by their blue colour. The leaves
are stalked, roundish in general outline, and divided down to the
leafstalk into three segments, of which the lateral two are again
divided nearly to the leafstalk, thus making five principal divisions,
which are wedge shaped at the base. Each of these again is
sub -divided twice or thrice into nearly opposite linear, tapering, acute
segments, of which the lowest are the longest, and these segments
are somewhat spreading.
Microscopic Characters. — The epidermis of the leaf consists of
sinuate tabular cells, those on the upper side being comparatively
large, whilst those on the under side are smaller, with thicker
and more acutely sinuate. Stomata occur on the under side only.
A single layer of palisade cells is found in the upper part of the
mesophyll, and spongy parenchyma in the lower portion.
ACONITI RADIX.
Aconite Root. — Racine d’Aconit. — Sturmliutwurzel.
Macroscopic Characters. — The root of Aconitum napellus should
be collected from plants cultivated in Britain. As the root
is in perfection in the autumn, it is best collected during
October and should then be crowned with the scales of an
undeveloped leaf-bud. The carefully dried root is from 6 to
11 Cm. long and 2 Cm. in diameter at the thickest part, and its
shape is that of an elongated cone, tapering very gradually.
It is dark brown in colour externally and marked with the
scars of broken-off rootlets, whilst internally, the root is white or
greyish- white, consisting mainly of uniform parenchymatous
cells loaded with starch granules. When the root is trans¬
versely cut and the fresh surface examined with a lens,
the large-celled pith is seen to be divided from the
bark by a narrow irregular line— the cambial zone — which
gives it the appearance of a star with five to seven rays, and at
each angle of the figure thus formed occurs a vascular bundle.
The cuticle is found only at the tips of the tubers and on adjoining
parts of the roots ; elsewhere it is replaced by brown paren¬
chymatous cells, part of the primary bark.
Microscopic Characters. — Aconite is one of the rare dicotyle¬
donous roots which retain their endodermis in spite of increasing
thickness. It occurs as a single layer of brown, thin-walled cells,
and is situated near the periphery of the root. The cells are tan¬
gentially elongated, with radial dividing walls, and separate the
thin primary or outer bark from the much more extensive secondary
or inner bark. The parenchyma of the primary bark also consists
of tangentially elongated cells, the walls of which are pitted, but
it contains in addition scattered yellow schlerenchymatous cells.
The parenchyma immediately within the endodermis is of the
same character as that of the primary bark, and also contains
stone cells which, however, are colourless. Proceeding inwards,
the parenchymatous cells become smaller and roundish-polygonal
in shape. They are also seen to be arranged radially and at last
become replaced by the smaller roundish-polygonal elements of the
pith and the bast rays. The sieve tubes are arranged in this latter
tissue concentrically, but irregularly scattered, and are easily dis¬
tinguishable in transverse sections, as though small, they are
characterised by strong, sloping sieve plates. At each angle of
the star-shaped pith is a vascular bundle, and these bundles are
connected with each other by the cambium layer. The woody
portion of the bundles consists for the greater part of parenchyma
with intercellular spaces. The pith consists of large-celled poly¬
hedral parenchyma, and like the parenchyma of the secondary bark
contains an abundance of starch grains.
The Powder is somewhat yellowish, and almost odourless, with a.
sharp burning taste. It consists largely of starch, of which the
grains are small and joined together. On treatment with potash
solution all the tissues are easily distinguished, more particularly
the stone cells, vessels with reticulated and spiral thickenings,
and those with bordered pits. Especially characteristic are frag¬
ments from the region of the endodermis.
AMYGDALA.
Almonds. — Amandes. — Mandeln.
Macroscopic Characters. — The fruit of Primus amygdcdus, Baillon,
from which almonds are obtained, is a drupe, differing from the
plum in having a velvety surface and firm flesh, besides splitting
open when mature and exposing the stone or endocarp. In out¬
ward appearance, form and structure, sweet and bitter almonds
are alike, and there are several commercial varieties of both. In
general, sweet almonds are larger than bitter, whilst the Jordan or
Malaga almond is longer and narrower in proportion than other
varieties. On one edge of the seed, near the narrow
end, occur the remains of the funiculus or seed-stalk
which extends half way down the seed to the point of
attachment to the shell or ovary. Maceration in warm water
enables the testa or brown outer coat of the seed to be readily
removed, the translucent white tegmen or inner coat coming away
at the same time, and the raphe may then be clearly distinguished
as a line extending from the end of the funiculus at the narrow
part of the seed, to the broader end where the circular chalaza is
visible. From the chalaza a number of veins radiate. A trans¬
verse section of the seed shows it to consist of two large
exalbuminous cotyledons, and on splitting these apart the radicle
is found projecting slightly from the pointed end of the seed.
Microscopic Characters.— Inside the characteristic epidermal
layer of irregular, finely pitted, brown cork cells is found the outer
seed coat, consisting of roundish-polygonal, brown-walled cells,
part of which are somewhat thickened and lignified, with numerous
pits, the rest being thin-walled and unlignified, and partially
collapsed. Bundles of spiral vessels occur in this tissue, accompanied
by numerous cells containing single and clustered crystals of calcium
oxalate. The inner seed coat consists of two layers : the outermost of
numerous rows of cells so closely compressed that they can hardly
be distinguished ; the other a single row of polygonal cells with
colourless walls, and containing oily and proteid matter. The
cotyledons consist of thin-walled, polygonal parenchyma, and
occasionally traces of woody bundles may be detected. The cells
are rich in oil, granular proteid matter, and sugar.
AMYLUM.
Starch. — Fecules. — Starke.
Macroscopic Characters. — The principal starches used in pharmacy
are those of wheat, Triticum sativum; maize, Zea mays; and
rice, Oryza sativa. As found in commerce they occur as fine,
white, inodorous powders, or in masses of irregular shape, which
are readily reduced to powder.
Microscopic Characters. — The grains of wheat starch are very
variable in size, the larger ones measuring from 30m to 36m in
diameter, and the smaller from 8m to 9m- Both larger and smaller
granules may occasionally be met with. The larger forms
are single, flattened or lens -shaped, and when lying flat appear
round or somewhat kidney-shaped, with a central hilum sur¬
rounded by faint concentric striae, but when standing on edge
they appear spindle-shaped, and the hilum and striae are of
course invisible. The smaller granules are also for Z the
most part single, and spherical or oval, but amongst them
may occur compound grains consisting of two or three small
granules. Maize starch granules are more uniform in size,
measuring from 10m to 25m in diameter. They are round or polygonal
with rounded angles, and generally have a very distinct star-shaped
hilum but no strite. Rice starch is also very uniform in size, but
much smaller than maize, the granules not exceeding 6m to 8m in
diameter. They are polygonal, and frequently, though not always,
show a conspicuous hilum. In reality they are the fragments of large
oval compound grains, such as may occasionally be found intact.
{To he continued.)
Feb. 27, 1897]
PHARMACEUTICAL JOURNAL.
171
Vj . '*
I. Aconiti Folia. -A, Leaf; B, Flower; C, D, Stamens (all J uat. size). II. Aconiti Folia (after Vogl) — A, transverse section upper epidermis ; 6 lower
epidermis; p, palisade tissue ; sp .spongy parenchyma with spiral vessels (x 200). III. Aconiti Radix -A (nat. size) i; B, .^"sveise t
after? Tschirch and Oesterlo.
PHARMACEUTICAL JOURNAL.
[Feb. 27, 18S7
PHOTOGRAPHY IN NATURAL COLOURS.
The stir caused by the publication of Chassagne’s process in
natural colour photographs has not been confined to photographic
circles. Details of this process have already been published in
the Journal {ante, pp. Ill and 132), and it is therefoi’e only neces¬
sary to proceed to look into it a little more closely.
The first thing that strikes the observer is that the plates are said
to be specially prepared, and the question is What is this special
preparation ? It is admitted that the negatives are like ordinary
negatives, and therefore it cannot be far wrong to assume that
this preliminary preparation is nothing more nor less than sensi¬
tising for colour, because if it is not this, it is obvious that we can¬
not possibly obtain anything like a correct reproduction of the
colours, and for this reason. If we photograph a bright yellow cross
on a blue ground, the yellow will photograph black and the blue
white in the print, and it would be impossible to make the black
cross in any way represent the luminosity of bright yellow, no
matter how much dye was absorbed.
The discovery, or rather the most curious part of the discovery,
s how to cause the silver image to select just the correct
amount of dye to simulate the natural colours of the objects.
Three dyes are used, first a blue, then a yellowish green, and
finally a red. Captain Abney has suggested that the secret solu¬
tion which is used to fcathe the plate or print prior to dyeing may
be albumin and salt, and it would be interesting to know the
reason of this assumption. If this were the case, it is obvious
that the medium would permeate the whole film, and if Abney’s
idea is that the albumin is coagulated by the dye, then the whole
of the film would be stained.
It seems far more probable that the secret solution is a
salt of some kind which so acts on the silver salt as to enable
it to form a lake with the dye, and it would possibly be worth
while to try some of the colourless salts — for the solution is colour¬
less — that are used in dyeing. Take, for instance, such a salt as
stannic chloride ; might not some tin salt be precipitated on the
silver which would act as a mordant for the dye ? If this is the
case, it yet remains to be explained how the colours are selected,
because one would assume that the first dye would be deposited
everywhere, and this being blue, why does the yellow show up
alone, and why in other places the red ? Of course it is quite
possible that the one is acid, another alkaline, and the third
neutral in reaction.
The opinion of one who has seen both results and solutions is
that, at a guess, the colours of the dyes are those of methylene blue,
a mixture of naphthol yellow and naphthol green, and cochineal
red respectively. The results cannot be said to be vivid, and
have far more the appearance of prints stained with aqueous solu¬
tions of dyes, a very old method of colouring prints, but we are
still face to face with the statements of Sir H. Trueman Wood and
Captain Abney that no brush was used and that the silver appears
somehow endowed with the power of selective absorption of the
colours.
An extremely interesting process, which has attracted very little
notice in England, is that proposed by Vallot in 1892. He suggested
a mixture of “ poudre d’aniline ” (? aniline red or ponceau), Victoria
blue, and turmeric in alcohol, on which paper was floated and then
exposed under a coloured transparency for three or four days to
sunlight, when all the colours of nature were obtained. The
idea of this was that the coloured light would bleach all the dyes
that were not approximately of the same colour.
Another process, suggested by M. Graby, is described in the
Bulletin Beige de Photographic, the plan adopted being to immerse
gelatino-chloride paper in a 4 per cent, solution of hydrochloric
acid, and then expose to daylight till it turns violet, he., till the
violet silver subchloride is formed. It is then dried and immersed
in a 1 per cent, solution of bichromate of potash, and expose to
light, when dry again till the whole of the gelatin has become in¬
soluble. Finally, it is immersed in a bath of—
Water . _ . . . 70 C.cm.
Nitric Acid . . . 5 Drops.
Mercuric Nitrate . 2 C.e.
Hydrochloric Acid . 3 C.c.
Sulphuric Acid . 1 C.c.
Chromic Acid . 1 -5 G.
Soda Alum . 3 G.
and exposed whilst damp. To obviate this, which is a difficulty,
the paper is treated with hydrochloric acid and bichromate,
exposed and immersed in mercuric nitrate and dried, exposed and
immersed in acetate of lead, and transferred like a carbon print.
According to M. Graby this process is quite different to that-
of Lippmann’s interferential colours, and blue is formed by the-
retention of the chlorine by the subchloride, red is formed by
some of the chlorine being given up, whilst yellow is formed by the
bleaching of the red and blue subchlorides, and the combination
of the chromic acid with the silver, which is fixed by the acetate
of lead. This explanation is ingenious, and the method may be
tested shortly, but the one essential, good daylight, has been
wanting for some time.
It should be pointed out that this proeess is somewhat on the lines
of the experiments of Poitevin and Becquerel, who used silver
subchloridc, but more nearly approaches that of Kopp, who.
soaked paper in chloride of zinc and sulphuric acid, dried it,,
and then in a mixture of potassium bichromate, cupric sulphate,
and mercuric nitrate, and very good results are attainable by this
process.
UN’GUENTUM IIYDRARGYRI NITRATIS*
BY P. W. SQUIRE.
When the formula of the United States Pharmacopoeia and that
of the British Pharmacopoeia are compared, certain differences will
be noted in the following details : —
1. The nature of the fat.
2. The relative quantity of nitric acid.
3. Manipulation.
1. Regarding the fat. — The U.S.P. employs lard oil, whilst the
B.P. uses a mixture of lard and olive oil.
About fourteen years ago Reichard published a series of experi¬
ments following the U.S.P. formula of that date, but using differ¬
ent kinds of fat. The fats used were (1) castor oil, (2) neat’s foot
oil, (3) linseed oil, (4) vaselin, (5) cosmoline, (6) oleic acid, (7) sweet
almond oil, (8) lard oil, (9) cotton-seed oil, (10) lard, (11) lard and
lard oil, (12) lard and cotton-seed oil, (13) lard and sweet almond
oil, (14) castor oil and sweet almond oil, and, lastly, butter.
After tabulating the results, he summed up as follows : — It is-
the author’s opinion that the present base for citrine ointment,
lard oil, though not being perfect in all respects, has the fewest,
objectionable features, and that its adoption is a decided step
towards perfection.
Considering the variety of fats and mixtures of fat which were
tried, it is curious to note that a mixture of lard and olive oil,
which has been official in this country for fifty years, does not.
appear in the fist. In U.S.P. lard was ordered until 1880, since
that date lard oil has been used. I prefer the mixture of lard and
oil. The action with nitric acid takes place at a lower temperature
with the lard oil, but the resulting colour is somewhat darker,
otherwise there is not much to choose between them.
Feb. 27, 1897]
PKARMACEUTICAL JOURNAL.
173
2. Quantity of acid : — The relative quantity of acid employed in
TJ.S.P. has remained at the same since 1870, but that of B.P. has
been altered considerably. The proportions in B.P. 1864 were
somewhat in excess of that selected for U.S.P. 1870 and 1880, but
this quantity was increased 25 per cent, in B.P. 1867, and adopted
in B.P. 1885.
5. The manipulation : — U.S.P. treats the lard oil with part of
the nitric acid, previous to the addition of the solution of nitrate
•of mercury. By the B.P. method the acid solution of nitrate of
mercury is added to the ointment basis without any previous treat¬
ment with acid.
The temperature at which effervescence takes place varies con¬
siderably with the mixtures (1) nitric acid and lard oil, (2) nitric
-acid, lard, and olive oil, (3) acid solution of nitrate of mercury and
lard oil, (4) acid solution of nitrate of mercury, lard, and
olive oil. With No. 1 the action is slight at 100° C.
<2J2° F. ), and brisk at 110° C. (230° F. ) ; with No. 2
the brisk action takes place at about 120° C. (248° F. ) ;
with No. 3 it occurs about 90° C. (194° F.), and with No. 4 at 95° C.
(203° F.). It is clear that the action takes place at a much lower
temperature with 3 and 4 than with 1 and 2, but the higher tem¬
perature does not matter so much in the case of 1 and 2, because the
mercuric salt is not present. It is important, however, that the
temperature should be kept as low as possible after the addition
of the mercuric solution, when the tendency to blacken increases as
the temperature rises ; the change will occur even if the ointment
be kept at 100° C. (212° F.) for anything like an hour, and possibly
in much less than this time. The advantage of treating
the fat with nitric acid instead # of with solution
of nitrate of mercury, is that in the former case the
temperature required to produce the effervescence is not
allowed to affect the mercuric nitrate, that being added afterwards
at a much lower temperature, and, therefore, the process is
safer.
But a satisfactory ointment can be made by the latter method, if
the temperature be kept as low as possible, and there is no advan¬
tage, but rather the reverse, in using a high temperature. As a
very high temperature has been suggested, I made the experiment of
allowing the action between the nitrate of mercury solution, lard and
oil to take place at 110-120° C., to which it quickly rises, even on a
water-bath, and then increased the heat up to 150° C. no further
action ensued, but the mixture darkened in colour. When using
the B.P. method the mercuric nitrate solution should be added
to the melted fats when both are at a temperature between
80° (176° F. ) and 90° C. (194° F. ), but not above 90° C.
(194° F.), and the mixture heated on a water-bath. The action will
commence between 90° C. (194° F. ) and 95° C. (203° F.), and vrill
run up quickly to 110° C. (230° F.) or even 120° C. (248° F.) ; effer¬
vescence should be allowed to continue for about ten minutes, and
then the product should be removed from the water-bath and
stirred till cold. The advantage of a water -bath is that no greater
temperature than 100° C. can be applied, but any other appliance
fulfilling the same condition would no doubt answer equally well. If
the ingredients be at 100° C. (212° F.) when the mercuric solution is
added as directed in B.P. 1885, the temperature will run up
vapidly to much higher than 120° C. , and the appearance of the
ointment is very likely to be damaged. An alternative method,
and one which has answered very well in my laboratory, is to
use the ingredients in the proportions given in the B.P. formula,
but treating the mixture of lard and oil with half the nitric acid
previous to the addition of mercury. The lard and oil should be
beated to 100° C. (112° F. ) and the nitric acid added. The heat
should then be gradually raised until bri k effervescence takes
place. Effervescence will commence about 105° C. (221° F. ), but
not briskly until it reaches 120° C. (248° F. ), when the heat should
be turned off. Chemical action will then raise the temperature
several degress, but this will not matter. When the effervescence
has ceased, allow the product to cool to 60° C. (140° F.), then add
at the same temperature the mercury, which has been dissolved in
the remaining half of the nitric acid, and stir the product until cold.
It is important that the ingredients should be diligently stirred
whilst the effervescence is proceeding, otherwise the contents may
be ejected from the vessel. . . . . , _
NOTE ON VINUM COLCHICI.*
BY R. C. COWLEY.
The principal constituents present in colchicum corm are
colchicin, fatty oil, resins, and starch ; the latter being abundantly
present.
It is frequently stated in text books on materia medica
and pharmacy that the colchicin may be extracted with either
spirit or acetic acid.
Considering the large amount of literature published on
colchicum, it has been a matter of surprise to me that no one
appears to have investigated the relative solvent action of these
menstrua.
The only preparation now official in which acetic acid is em¬
ployed is the acetic extract, although acetum colchici had a place
in the Pharmacopoeias of the London, Edinburgh, and Dublin
Colleges. These preparations appear to have been looked upon
by some authorities as unreliable.
It occurred to me that if the alkaloid was more soluble in acetic
acid than in alcohol, an acetic extract would be a very suitable
substance to employ in making vinum colchici, in a somewhat
similar way to that ordered in making ipecacuhana wine of
the Pharmacopoeia ; the product of hydrolysis, if any should occur,
being colchicein, a substance which is apparently no less active
medicinally than colchicin.
The sample of the corms employed in my investigations was a
very fine one, all the pieces having a yellowish exterior, and in
transverse section was nearly white.
I prepared a number of solutions from the drug.
No. 1 was made by macerating the powdered corm in strong
acetic acid for twenty-four hours, then diluting to B.P. strength
and macerating for six days longer.
No. 2 was made with diluted acetic acid, macerating for seven
days. Both were now evaporated down on a water-bath to an
extract. This 'extract was macerated in sherry of 17 per cent,
alcoholic strength. |
No. 3 was made according to the Pharmacopoeia.
No. 4 was a proof spirit solution made by maceration as last.
The percentage of alkaloid was found to be as follows : —
No. 1 . ... . . -041
No. 2 . . . _ . 047
No. 3 . ‘041
No. 4 . -058
In colour, the first two are considerably darker than the B.P.
product, No. 2 being darker than No. 1. Before experimenting, I
was inclined to believe that the acetic extract method would
yield a product much richer in alkaloid than that prepared by the
B.P. method, but the above results show there is very little
advantage gained, and further that a proof spirit menstruum
extracts more alkaloid under the same conditions than acetic acid
or sherry does. .
* Read before the Liverpool Chemists’ Association
174
PHARMACEUTICAL JOURNAL.
[Feb. 27. 1897
THE BOTANICAL INSTITUTE AND GARDEN AT
MARBURG.
BY W. HARRISON MARTINO ALE.
The botanical institute and gardens form one of the most
interesting features of the University buildings, and for that matter
of the town of Marburg.
The Institute is surrounded entirely by the lovely garden, and
will claim our attention first, to take a stroll in the garden after¬
wards.
Built in 1875, surrounded by dark green foliage, the red sand¬
stone of which it is composed shows up to perfection its Gothic
style, still the beautiful building has for long been too small to
accommodate the influx of students from home and across the
seas. For this reason since the taking of the accompanying photo¬
graph — in the summer of last year — a new wing almost as large as
the edifice seen has been added to the east end — that is to the
end of the auditorium (now microscopical laboratory), which
forms the right-hand portion of the building in the picture ; the
photograph, therefore,
does by no means
credit to the present
size of the building.
In order to under¬
stand the doings at
the Institute we must
first know the pre¬
siding professors —
Professor Arthur
Meyer and Professor
Kohl — and it is indeed
out of the question to
say which is the more
genial of these two
popular professors.
We will visit them
seriatim.
Professor Meyer' is
characterised by a
very subtle humour
combined with a
beaming smile. I re¬
cently had an hour’s
very pleasant conver¬
sation with him, during which he told me many things concerning
the improvements now in progress in the enlarged Institute.
The new wing will contain an Auditorium with 160 places, and
the old Auditorium, as already stated, will be converted into a
Microscopical Laboratory, in which 40 places will be arranged for
Practical Botanical Microscopy, and the Microscopic Examination
of foods and drugs.
Above the new Auditorium will be Departments for Physiologi¬
cal- physical Investigation , and for the “ Pharmocognostic ” (materia
medica) collection — founded by’jProfessor Wigand, who died here in
1886.
The whole of the ground floor of the principal building, with ex¬
ception of a room set apart for preparation of lecture specimens
and experiments, is to be devoted to the Botanical Collection.
Above, the professors’ sanctum and separate laboratories for
advanced students in botanical research, for practical investiga¬
tion of bacteria and fungi, and for physiological examination of
the same.
The Professor mentioned that he was having his “Directions”
(by which the students work in the “ Microscopische Practicum”),
printed, in place of the copying press hitherto made use of. It is a
certain assumption that these “ Directions ” will be utilised in other
universities in the same measure as the Professor’s ‘ Pharmacog-
nosie ’ is used. He hopes to obtain another three or four thousand
marks in addition to the six thousand that have recently been
spent on laboratory plant, and he was of opinion that Government
control — providing the Government be good — which, of course,
Germany’s is, was better than any other supervision.
In America, he said, a community of a probably business-like
turn of mind arranged a curriculum, and that curriculum had te
be “ got through,” probably term after term, without taking into
consideration the requirements of the moment — the smartest
business man probably obtained this post. In Germany, on the
other hand, the Science Investigator receives his appointment by
virtue of these investigations— services in science rendered— and is
then at liberty to arrange his course of lectures and practical work
as he thinks fit, and to suit them to the advancement science may
have taken at any particular epoch, or which other influences may
indicate, at his own
free will.
A good teacher
must, he remarked, of
necessity beone skilled
in original research,
and the science of
bacteriology must,
without doubt fall
under the sway of the
science of botany.
Professor Meyer re¬
quires three or four
semesters’ work from
a student for gradua¬
tion, providing he
works, has acquired
the “methods,” has
produced a good
“ arbeit,” and is com¬
petent to enter the
scientific world as a
reliable botanist —
capable of carrying
on research.
All pharmaceutical, as well as chemical and zoological students
who graduate are required to take a course of practical microscopy
in the Institute.
As to lectures, next semester the Professor reads “ General
Botany” daily 7 a.m. ; “ Physiological and Biological Demonstra¬
tions in the Garden” with the living plants one day a week j
“ Classification of Angiosperms” one day ; besides superintending
“ Practica” and daily work in the Institute by advanced students.
Let us now visit Professor Kohl, an almost next-door neighbour of
the Professor we have just left, on the ReuthofFstrasse, overlooking
the beautiful Latin Valley, one of the steepest hills in Marburg.
Besides being a distinguished botanist, Professor Kohl has done
some marvellous work in photography and microphotography, and
is President of the Photographic Club.
He reads next semester, “ Algae and Lichen es ; ” “ Chemical-
physical Processes in the Vegetable Cell ” ; “ Exercises in Recog¬
nition of Plants in Connection with the Excursions.” Each one
day a week, and conducts the excursions in the surrounding hills.
At this point must be mentioned his excellent work on the Flora
of the District.
THE BOTANICAL INSTITUTE, MARBURG. — SOUTH AND WEST SIDES.
Feb. 27, 1897]
PHARMACEUTICAL JOURNAL.
175
The garden is watered by a canal from the river, and is indeed
a, garden the town may be proud of, doing great scientificand agri-
_ -cultural service.
It contains some beautiful trees, and was arranged 1810-1814 by
Professor Wenderoth ; its present form, however, is greatly due to
Professor Wigand, to whom a statue is erected by former pupils in
the garden.
The North American water pest ( Elodea canadensis) unfortu¬
nately ousts contemporaries from the lake in the garden, which is
•divided into two parts, a systematically arranged and a geogra¬
phically classified portion.
In the former the German flora is completely represented, and
in the latter North America is well to the fore. Especially notice¬
able are the marsh cypress ( Taxodium distichium), two tulip trees
( Liriodendron ), magnolias, a large specimen of Aristolochia sipho,
■etc.
The glasshouses, in the east end of the garden, include a
Victoria regia house, departments for foreign plants, ferns, cacti,
nepenthe var., cephalot^us, sarraceina, and other insectivorous
members.
The Edelweiss and other alpine flora, are all to be found in an
^especially cool corner, and if you will glance again at the photo¬
graph you will notice a bold creeper on the south side. This is the
Bignonia grandiflora — the Uncle Tom’s Cabin — famed trumpet ash.
Here, however, the shoots, which grow out at right angles to the
wall, are not trimmed off annually as is the case at Glebe Cottage,
Winch elsea, for example ; these outstretching arms, a couple of
metres long, or almost so offering you so, temptingly seven or eight
beautiful orange-red trumpet flowers, cannot fail to attract the
most half-hearted lover of flowers.
VISIT TO A PARISH DISPENSARY.
T has been thought that
the readers of the Journal
would like to know what
progress has been made
in dispensing for the poor
since Dickens wrote of the
parish doctor’s servant,
who, in the absence of
her master, gave a patient
some medicine, and on the
doctor’s return, in answer
to his query if anyone had
called, she said, “Only
old So-and-So ; I gave him
Fig. 1. — Counterfor Preparing Galenicals. & bottle of picalilly , as he
had red cabbage last time and it did not suit him,” these names
being on the jars containing the stock mixtures usually supplied
to the patients.
As a matter of fact, the dispensing was not all that could be
desired, and to remedy this state of affairs the Local Government
Board issued an order in 1871 authorising guardians of the poor
to establish dispensaries for the supply of medicines.
This was done, one or more dispensary being opened, according
to the size and needs of the parish. These dispensaries have gone
on improving ever since, until to-day they are certainly not behind
a modern pharmacy, that is to say, if they are all conducted on the
same lines as the one I visited.
I called in to see the South St. Pancras Dispensary, which is
situated in Clarendon Square, Somers Town, in the midst of a
densely populated district. It was about 11 a.m. , and I found
everything going on as busy as a hive ; in fact, they were so busy
that I thought I had better postpone my visit to a more convenient
season. But Mr. Miller, the dispenser, said there was nothing
like the present time, and kindly allowed me to look over the
establishment.
The patients were sitting in the waiting-room, those waiting for
their medicine at one end, and those waiting to see the medical
officers at the other, everything being conducted in a regular and
orderly fashion. There are five medical officers, one due every
hour from 9 a.m. until 1 o’clock. The district dispensed for
extends from Oxford Street to Primrose Hill, thence vid the
Regent’s Canal to King’s Cross, along King’s Cross Road to Clerken-
well Prison, crossing again at an angle to the Oxford Music Hall.
In the dispensary everything was in good order, a condition abso¬
lutely necessary where so much work has to be done. The
Fig. 2. — Tlie Distributing Counter.
prescriptions are taken in at one end of the counter, and are given
out at the other end through openings similar to a booking office at
a railway station (see Fig. 2).
I was most agreeably surprised to see a great variety of prescrip¬
tions, as I had expected to find a great similarity. There were
mixtures, pills, powders, ointments, plasters, suppositories, cap¬
sules — in fact, every variety of pharmaceutical preparation and
dressing, all free and no stint. When necessary, steam kettles,
inhalers, etc., are lent out, the dispenser always hoping to see them
again ! Patients are fitted with trusses and every other kind of
surgical appliance.
The average number of prescriptions is close upon one hundred
daily, and as most of the patients are supplied with sufficient
medicine to last a week, it will give some idea of the quantity
consumed. Looking round the dispensary I was astonished to see
the completeness of the stock fittings and apparatus. There was
apparatus for testing urine, including a microscope for examining the
deposits. I found a hydrometer for testing the strength of the
spirits. Port wine, brandy, gin, and whiskey are supplied by the
Guardians when these stimulants are ordered by the doctor. The
dispenser is held responsible for their being of proper strength
and they are examined every six months by the stocktaker, who
176
PHARMACEUTICAL JOURNAL.
[Feb. 27, 1897
also takes stock of the drugs, chemicals, instruments, etc., and
reports to the Guardians as to their condition. There was a
balance for taking the specific gravity of the liquids as they are
received into stock from the contractors ; also wash bottles,
burettes, in fact everything necessary for properly conducting a
pharmacy. After the medical officers have gone things get a little
quieter, only the patients who are visited at their own homes
dropping in for their medicine in the afternoon ; this gives the
dispenser time to look over his stock and prepare for to-morrow.
Fig. 1 shows the counter where the tinctures, pills, plasters, etc.,
are made. Here were arranged a row of glass jars with tinctures
in process of maceration ; in one I saw four pints of tr. nucis vom.,
in others tr. lavand. co., tr. digitalis, tr. rhei, tr. catechu, etc..
There was a percolater with tr. zingib. fort. , another with lin.
bellad. Everything is prepared in strict conformity with the B.P.,
Fig. 3. — Closed Fire for Ointment Making.
and not on the principle that anything is good enough for a
pauper, as some imagine. There were glass jars containing solu¬
tions automatically prepared by an original and ingenious
device of Mr. Miller’s, a description of which may be
useful to those of our readers who have to prepare them
on a large scale. The substance to be dissolved, say
ammon. carb., is placed in the stopper of a sixty-ounce
drying bottle, the bottom of the stopper is covered with gauze. The
bottle is filled with distilled water. On adjusting the stopper, so
that the water reaches the ammon. carb., a solution is prepared in
a few hours without labour. The same process may be used for
other substances, including gum acacia. The large jars in Fig. 1
contain aq. menth. pip., aq. camph., liquor calcis, infusion of
gentian, infusion of senega, etc.
Fig. 3 shows the closed fire where the ointments are made ; the
insurance company making it a condition in the policy that no
ointments shall be made on an open fire.
The guardians are to be highly commended for their wisdom in
making such provisions for the sick poor of their parish, and we
hope that those of our readers who are guardians will see that the
same' state of affairs exists in their parishes and unions, and that
none but registered chemists and druggists shall have the making
and dispensing of the medicine.
LEGAL HINTS FOR PHARMACISTS.
“ ’Tis not in mortals to command success,” and chemists, like
other specialists, are perhaps less likely to hit the golden mark
than other men, for their scientific training must necessarily have
a tendency to withdraw their minds from ordinary mundane con¬
ditions and duties. But chemists, in common with Cato and other
mortals before and since, can deserve success, and one of the first
steps in that direction is to acquire a knowledge of the laws and
regulations affecting their calling ; of the imposts and taxes
incident not only to their position as workers in an ancient and
honourable craft, but as citizens of a great empire. There is a
difficulty, however, in this first step arising from the mass of more
or less meaningless verbiage in which laws and regulations are
wrapped. One cannot expect men in business to go through each
enactment on the Statute Book and sift the grain of wheat it may
contain from the bushel of legal chaff which it is sure to provide.
In this connection there seems to be legitimate scope for the
epitomiser, and perhaps the Pharmaceutical Journal cannot more
usefully contribute to the well-being of registered men than by
presenting in a comprehensive form the gist of the more im¬
portant regulations affecting them.
To take first the important subject of
Methylated Spirit
in so far as it affects or is likely to affect the retail chemist. This
is one of the Inland Revenue licences appropriated to the Imperial
Account, and the conditions regulating the retailing and use of
the spirit are imposed by a special section of the Spirits Act,
1880, supplemented by general orders of the Board of Inland
Revenue.
General Observations. — No person who is a distiller or
rectifier of spirits, or who holds a beer, spirit, or sweets licence,
can obtain a licence to retail methylated spirit, but the
fact of a chemist holding an excise licence to cover the sale of
such spirituous preparations as “ coca wine” would not be
a bar to his being authorised to retail methylated spirit.
The licence duty is 10s. per annum, and must be renewed
on October 1 each year, as long as the retailing con¬
tinues. It is well to be particular as to renewal, for the penalty
for retailing without a licence is £50, and the Revenue authorities
deal hardly with transgressors. It is noteworthy, too,
that infancy — which oft times operates so successfully as
a defence in our Courts of Law, cannot be urged with any effect
in a breach of the Revenue Laws. The licence, although a
personal thing may, under certain conditions, be transferred — -
always provided that notice is given to the Board, and that the
transferee is not within the official category of prohibited persons*
One licence does not cover more than one set of premises.
Inspection of Premises. — Before a licence is granted, the
premises of the prospective licencee must be entered by the super¬
visor or other official, and surveyed. The survey must take place
in the presence of the retailer, who is required to indicate the
place or places in which he intends to keep or sell the
spirit. This is important, for if, afterwards, any unauthor¬
ised rearrangement is made, and the retailer thoughtlessly
keeps or sells in any but the licensed place or places, he becomes
liable to a fine of £50 with forfeiture of spirit and licence. The
licensed premises are always open to entry by an officer of Revenue
between sunrise and sunset, and such officer may purchase samples
of spirit for investigation. Obstruction to this portion of an officer’s
duties carries the usual fine of £50. Stock is also periodically
checked, and a retailer may be required to keep a stock account in
the manner prescribed by the Board.
Prohibitions. — Having obtained his licence the retailer should
make himself acquainted with the things he must not do — a species
of official commandments, and it will be convenient to give these ira
tabular form : —
(а) Must not sell between the hours of 10 p.m. on Saturday and S a.m. on the
following Monday. Penalty £100 for each offence.
(б) Must not sell or possess methylated spirit containing any essential oil or
flavouring matter, or which does not contain three-eighths of one per cent, of
mineral naphtha.
(c) Must not possess at any one time a greater quantity of spirit than fifty
gallons, and must not sell to any one person a quantity exceeding one gallon.
(d) Must not receive methylated spirit from any person except an authorised
methylator or retailer. In the latter case the quantity must not exceed one;
gallon at a time.
Ordering. — If a chemist merely desires to keep a small stock, it
will be much more convenient for him, assuming that he is not aji
•authorised user of unmineralised spirit, to buy in quantities of ones
gallon or less from another licensed retailer, for this method will
Feb. 27, 1897]
PHARMACEUTICAL JOURNAL.
177
obviate the use of a requisition book and consequent formalities.
But if the chemist aspires to not only retail methylated spirit,
but to supply brother retailers, he must, having picked upon
his authorised methylator, obtain a requisition hook from the
supervisor of his district, and order in the form there prescribed.
He must order in five-gallon lots, and for his own protection should
see that the consignment is in perfect order. In the first place it
should be accompanied by a “ permit,” and must be in accordance
with the quantity mentioned in the requisition. No vessel in the
consignment must contain less than a reputed quart, and each
vessel must be distinctly labelled with the words “ Methylated
Spirit.” The mention of these points may seem trivial, but it
must be borne in mind that the acceptance of a lot not quite in
order may place the retailer in a difficulty, for the methylator is
not permitted to accept the return of any portion of the spirit
without special permission in that behalf.
Use of Methylated Spirit. — A retailer of methylated spirt
does not require any special permission to use the spirit — which is
understood to be the mineralised spirit — in the manufacture of
soap, compound camphor, aconite and belladonna liniments, but
if he should desire to employ ordinary, i.e., unmineralised spirit, for
use in any art or manufacture, he can only do so by obtaining the
sanction of the Board of Inland Revenue. This is not a difficult
matter. In the first instance the application should be addressed
to the supervisor of the district, and the applicant should state the
situation of his premises, describe particularly the purpose for
which he requires the spirit, and intimate the probable quantity
per year he is likely to want. If this quantity is less than fifty
gallons, there need be no question of bond beyond the applicant’s
personal undertaking to use the spirit solely for the purpose
described. The presence of a still on the premises, however,
will render the authorities impervious to any personal under¬
taking, and in such a case a bond will be required for the
proper use of the spirit. A bond is also necessary where the
annual quantity used is more than fifty gallons. Having received
the requisite sanction, a retailer may obtain and keep for use
ordinary methylated spirit, notwithstanding that he stocks
mineralised spirit for trade purposes, but the two kinds of spirit
must be scrupulously kept apart. The formality of ordering
unmineralised spirit is similar to that already described for
mineralised spirit. The requisition book with its counterfoils
must be carefully preserved for production when required. And
they will be demanded at least four times a year, for the officers
are officially instructed to visit all users once every quarter, and
may at any time show their zeal by more frequent visitations.
It being so easy to obtain for legitimate purposes a supply of
ordinary methylated spirit, there should be no temptation for any
person to attempt the purification of the mineralised variety, but
should there be such a misguided individual, it is well that he
should know that the act renders him liable to a heavy penalty.
Purification of the ordinary spirit or its use in the manufacture of
absolute alcohol is also rigorously prohibited.
So far we have only dealt with the regulations affecting retailers
of spirit. But there are chemists in business who do not retail and
do not wish to retail the spirit, but who, nevertheless, have
frequent occasions for using the ordinary or unmineralised kind,
either for experimental purposes or for use in certain pharmaceu¬
tical processes. Bearing in mind the fact that no person is per¬
mitted to receive unmineralised spirit without sanction, the first
step is to send to the Board of Inland Revenue and obtain that
sanction. If it is a question of using the spirit in a preparation
which is not official in the B.P., the special formula should be sent
to the Board. The same process holds good if the spirit is proposed
to be employed in the compounding of certain medicines. The
reason is perfectly obvious, for the use of methylated spirit on
which there is no duty, as a substitute for dutiable spirit is a
matter touching the Imperial purse, and must necessarily be
placed beyond temptation. No person may prepare, or even
attempt to prepare, or sell any methylated spirit, either as
a beverage or as an ingredient in a beverage ; nor may he
possess or sell any article capable of being used in any way
as a beverage or medicinal drink in the preparation of which
methylated spirit or any of its derivatives has been used. Non-
compliance with any of these conditions is visited with a fine of
£100 for each offence and other contingent inconveniences. There
is, however, a relaxation of these conditions so far as the manu¬
facture of sulphuric ether, chloroform, and chloral hydrate is con¬
cerned, but the Board’s authority must be first obtained.
Still with all the formidable array of penalties which flanks the
law relating to methylated spirit the Board has no desire to
exercise its undoubted autocratic powers in a tyrannical manner,
and it has on many occasions given evidence of its recognition of
the difficulties which chemists are apt to meet with in the
ordinary course of their calling. There is really no occasion for
anyone to run the slightest risk, if in cases of doubt reference is
made to Somerset House ; and it * will be found, as it has been in
the case, inter alia, of substituting methylated spirit for alcohol in
the preparation of vegetable extracts, that the authorities there
are not indisposed to make reasonable concessions, which are
consistent with the efficient administration of the great
branch of the public service under their charge. The
moral appears to be, do not assume an independence of action
in relation to Somerset House, no matter how conscious you may
be of the rectitude of your motives.
Note. — The law relating to methylated spirit is applicable to
the whole of the United Kingdom.
Finish. — Closely allied to methylated spirit is the preparation
styled “ Finish.” This may be made by any person authorised to re¬
ceive methylated spirit, and by dissolving in every gallon of spirit
not less than three ounces of gum resin — usually shellac. When so,
prepared, “ Finish ” may be sold without licence. The article
must not be purified or altered except by the addition of more
gum resin or colouring matter, and this prohibition is fortified by
a penalty not exceeding £200 for each offence.
{To be continued.)
NATURAL HISTORY NOTES.
So many members of the craft are interested in various branches'
of practical natural history, such as botany, geology, entomology,
horticulture, etc., that it seems desirable periodically to devote
some space in the Journal to the discussion of topics of
general interest in these subjects. In this project both the-
indulgence and the co-operation of readers are claimed, since to
render the notes of value, dependence must be placed in great
measure upon communications from those interested in the various
subjects. Pharmacists, and in particular those who are so fortunate
as to be situated in rural districts, have often abundant oppor¬
tunity for observation and collection, the records of which cannot
fail to be of interest to their less happily situated colleagues. The
aim is not to reproduce in these columns abstruse and learned
dissertations, but it is rather intended to confine attention to facts
of general interest, such as may be within the scope of all the
members of the craft.
From his training, the pharmacist is eminently fitted to become
an observant naturalist, and that he is often able to attain distinc¬
tion in the various branches of animal and vegetable biology, which
can be followed in this country, is evidenced oy the prominent part
taken by many pharmacists in the various learned societies devoted
to this branch of science. Not only do his tendencies often lead
him to interest himself in these matters, but the public at large,
and particularly the more intelligent part of it, repair to him for
advice and instruction in the following of their hobbies in this;
direction.
Botany and entomology in their various branches are necessarily
the two sciences which will occupy the greater part of his attention,
and are in fact so dependent on each other that a good botanist
cannot fail to acquire some acquaintance with the insect world,
nor can an entomologist be ignorant of the plants upon which his
insects are so largely dependent. In these remarks attention is
confined to the practical worker ; the collector, as such, will
probably find a better outlet for his superfluous energy in the
acquirement of potsherds or postage stamps. Any communications
and observations intended for comment in the Journal should be
addressed to the Editor, headed “ Natural History Notes.”
Over-Collecting.— In his position as adviser to beginners in
collection, no naturalist should lose an opportunity of impressing
upon the neophyte the evil of over-collecting. Let the collection,
for some seasons at least, be confined to the actual gatherings of
the beginner. “ Exchanging ” is a necessary evil in both botany
and entomology ; it may be necessary to obtain a complete collection
for scientific purposes, but to the average field naturalist is scarcely
needful at first. Every specimen in the herbarium or cabinet
should afford its fortunate owner some pleasant recollection of its
capture, or throw a definite light on the life history of the plant
or insect that it represents, and a carefully compiled note-book
should be kept recording the date and other particulars of each
fresh object acquired.
{To be continued.)
178
PHARMACEUTICAL JOURNAL.
[Feb. 27, 1897
THE STUDENTS’ PAGE.
ON DISPENSING EMULSIONS.
In the previous notes on dispensing emulsions (ante, pp. 130 and
150) the use of acacia in emulsifying fixed oils, volatile oils, oleo-
resins, and soft paraffin was fully entered into. If the student
has followed the instructions there given he will have succeeded in
producing satisfactory emulsions with one of each of those classes
of drugs. As was pointed out in the concluding paragraph of the
latter of those notes, acacia is not the only agent that may, or
should, be used to produce an emulsion, and it is proposed now to
deal with emulsifiers other than acacia. Of these, yolk of egg
may be taken first.
Yolk of egg may be regarded as a natural emulsion of egg fat.
It has the property of emulsifying several times its volume of
many fixed and volatile oils, is easy to manipulate, and yields
emulsions that are more compatible with acids, salts, alcohol, etc. ,
than are those prepared with acacia. The principal disadvantage
lies in its proneness to decomposition, emulsions made with egg
yolk without the addition of any preservative keeping good
for a comparatively short time only.
The Use of Yolk of Egg.
To be certain of producing a good emulsion the egg must be
quite fresh and the yolk alone is to be used. Crack the shell of a
fresh egg about • the middle by a smart blow on the edge of a
spatula, the opposite edge of the spatula resting on the counter.
Insert the thumb-nail into the crack and, holding the egg upright
and over a measure, break the shell across into two nearly equal
portions, so that the yolk is caught in the lower half, part of the
white falling into the measure. Carefully transfer the yolk now
from one half-shell to the other, and back again, freeing it thus
as completely as possible from the white. Then throw it into the
mortar and triturate lightly with the pestle. Now measure a fluid
ounce of oil of turpentine and add it gi'adually to the egg-yolk,
triturating after each addition and thinning the emulsion with
a little water if necessary. When the emulsification has been
effected, the mixture may be diluted with water, and should then
be strained through muslin ; any other ingredients that may be
ordered should be added last. Such emulsions of turpentine
with yolk of egg thicken somewhat and improve in appearance
by keeping ; in this case the turpentine acts as a preservative.
Yolk of egg is the acknowledged emulsifier for spermaceti and
appears to be the best. The student should prepare a spermaceti
emulsion by the following method : — Take two drachms of sper¬
maceti and reduce it in a mortar with the aid of a little rectified
spirit to the finest possible powder. Allow the spirit to dry off,
and add now the yolk of a fresh egg, separated from the white as
directed above. Triturate until an emulsion is produced, which
may then be diluted and strained through coarse muslin. Care
must be taken not to allow the spermaceti to form hard lumps.
Paraldehyde, a refractory drug, may also be emulsified with the
yolk of egg, one egg-yolk sufficing for about an ounce of par¬
aldehyde. For solid, fats, such as marrow, which is sometimes
ordered as an emulsion, yolk of egg is the best emulsifier. In such
a case the egg-yolk should be raised to a temperature of about 45°
to 59° C. , and the melted fat at a temperature of 50° to 60° C. ,
gradually added. The emulsion should be diluted with water at
the former temperature, and stirred till cold.
Soaps and Potash as Emulsifiers.
The next emulsifier to which the student’s attention should be
directed is soap. This body possesses considerable emulsifying
properties, but for obvious reasons is in many cases unsuitable, and
is certainly inadmissible for internal use, unless specially ordered
by the' physician. The official turpentine liniment is such a soap
emulsion, which can be diluted with water to form a fluid emul¬
sion ; the student should prepare a few ounces of turpentine lini¬
ment according to the directions of the Pharmacopoeia and dilute
it, when made, with water.
Like; soap, solution of potash is sometimes used as an emulsifier
for certain oils and oleo-resins, but, like soap, its unauthorised
addition to a mixture, especially to one intended for internal
administration, is inadmissible. An official instance of the use of
this emulsifier is to be found in the mistura olei ricini, in which
six drachms of castor oil are emulsified by one drachm of solution
of potash. This mixture, and the best mode of making it, has been
the subject of much controversy. Apparently a slight variation in
the composition of the castor oil influences the resulting emulsion,
different samples of the oil yielding good or indifferent results by
the same treatment. Squire recommends the following as a good
method : — Mix intimately in a mortar the oils with the syrup and
add half the quantity of solution of potash, then gradually the
remainder of the solution of potash previously mixed with the
orange flower water. The student should prepare the official
quantity by both this and the official method.
In such a case the solution of potash owes its emulsifying proper¬
ties to the soap which it forms partly by combination with the
free fat-acids present in the oil, and partly by double decomposition
with other glycerides of the oil, yielding soap and glycerin.
Balsam of copaiba is a drug that is frequently ordered in con¬
junction with solution of potash. In this case the potash will effect
the emulsification of the balsam, and an elegant mixture will be
produced. For this purpose agitation in a bottle is preferable to
trituration in a. mortar. The student should proceed as follows : —
Measure two drachms of solution of potash into an eight-ounce
bottle and dilute it with half an ounce of water. Cork the bottle
and shake so as to moisten the sides of the bottle, and thus prevent
as far as is possible the subsequent adhesion of the balsam to the
glass. Now weigh into the bottle half an ounce of balsam of
copaiba, taking care that it fall directly into the dilute alkali.
Cork again and shake vigorously until emulsification is co'tnplete.
Here the oleo-resin contains volatile oil and a resin that possesses the
characters of an acid. This acid resin combines with the alkali to
form a soap by which the emulsification of the remainder of the
resin and the volatile oil is effected.
Although in this case solution of potash produces a good emulsion
with the balsam, the student must carefully remember that if the
choice of emulsifier is left to him, solution of potash must, on
account of its distinct medicinal properties, be avoided; his choice
should certainly fall on acacia.
Tragacanth, Quillaia and Other Emulsifying Agents.
The use of tragacanth has frequently been advocated as an
emulsifier, but possesses little to recommend it. The student
should prepare the following emulsion of turpentine with
tragacanth and compare it with the one made previously with
acacia. Introduce half an ounce of turpentine into a perfectly
dry 4 oz. bottle ; add to it ten grains of powdered tragacanth, and
diffuse this through the turpentine by shaking, add now about
two ounces of water and shake vigorously, and then dilute to four
ounces. The turpentine will be diffused through the mucilage,
and if the emulsion is kept, will rise as a cream to the surface, but
may be diffused again by shaking. But the sub-division of the oil
will have been much less completely accomplished than with
acacia, for the globules will probably be visible to the naked eye.
Tragacanth is, however, often employed with advantage to pre¬
vent “ the creaming ” of an acacia emulsion by imparting greater
viscosity to the mixture.
Tincture of quillaia made by macerating one part of quillaia
bark in four parts of rectified spirit, possesses to a remarkable
degree the property of emulsifying fixed or volatile oils, tars,
resins, etc. As, however, this preparation has a distinct
physiological action, its addition to an emulsion intended
for internal use cannot be regarded as justifiable, and
therefore, unless ordered, tincture of quillaia should be
used only for external remedies ; this unfortunately limits
the applicability of what would otherwise be a most valuable
emulsifying agent, for emulsions made with quillaia are more com¬
patible with acids, alcohol, glycerin, etc., than any others. Let
the student confirm this property of tincture of quillaia by emulsi¬
fying creosote in the following way : — Put a drachm of creosote
into a two-ounce bottle, add a drachm of tincture of quillaia,
shake and add an ounce of water, shake well and dilute to two
ounces. The creosote will be completely emulsified, and though
the oil will separate again on standing it will form a creamy
layer that can be easily diffused through the liquid. Many similar
drugs can be emulsified in this way with the greatest ease and
rapidity.
Other emulsifiers have been prepared and used, such as casein,
mucilage of Irish moss, condensed milk, etc., but they are but
little employed and possess no special advantages.
The dispenser is also frequently called upon to produce present¬
able mixtures with resins or tinctures containing resins or similar
bodies and water.
Resins can frequently be diffused through water by the use of
simple or compound tragacanth powder, but more elegant mix¬
tures are often produced by dissolving the resin in spirit and pour-
Feb. 27, 1897]
PHARMACEUTICAL JOURNAL.
179
ing the tincture thus produced into water previously mixed with
mucilage of acacia. The same method of procedure should be
adopted for all tinctures containing resins or bodies which, when
precipitated by water, have a tendency to form clots or unsightly
mixtures. In this class quinine and camphor must not be for¬
gotten. They are both amenable to treatment with acacia.
The student should practise the use of mucilage in such cases as
the following : Take a drachm of mucilage, dilute it with an ounce
of water and introduce into a four-ounce bottle ; shake it so as to
moisten the sides of the bottle. Add now a drachm of compound
tincture of benzoin, and shake again ; dilute to four ounces. The
resin will be diffused through the water in a state of fine division.
Tincture of Indian hemp, tolu, etc. , may be treated in the same
way.
The fact cannot be too strongly impressed on the student that
when the choice of an emulsifier is left to his discretion, he should
choose an emulsifier to which no objection can be taken, on account
of its medicinal action. In nine cases out of ten acacia will answer.
There are comparatively few emulsions that can be better prepared
by other emulsifiers.
THE FLOWERS OF FEBRUARY.
The Ranunculaceous plants in flower this month form a very
instructive series if compared together, and serve to throw light
upon the apparent want of agreement in the characters of the
several genera. The plants are as follow : — Ranuncuhis ficaria,
Eranthis hyemalis, Anemone hepatica, Helleborus niger, II. viridis,
H. faetidus, and Clematis indivisa. Thus, if we compare the roots,
R. ficaria has fig-shaped tubers, whence its specific name Ficaria ;
Eranthis has an irregular tuber, sometimes approaching a rhizome
in form, and the hellebores have a distinct rhizome. The plant
rarely ripens seed in this country, but gives rise to axillary tubers,
an interesting account of the development of which is given
in Shirley Hibberd’s ‘Field Flowers,’ pp. 17-19. With
respect to leaves, which in this family are usually radiate or
pedate-veined and divided into segments, the R. ficaria has
a cordate leaf, in which the space between the radiate
veins is filled up with parenchyma, and the same is the case
with the Hepatica ; Eranthis, on the other hand, is divided
into segments, like the aconite, whence its name of winter aconite.
In the hellebores the leaves are also radiate -veined, and consist of
three segments, divided down to the petiole, of which the two
lateral are again divided, but not so far as the petiole, so as to form a
distant resemblance to a bird’s foot, whence the name pedate,
applied to the leaves of this genus. In Clematis the lateral lobes
are not usually divided, but the central lobe is prolonged and
bears lateral lobes, so that the leaf assumes a pinnate foim. In
this genus the leaves are opposite, and the plants are woody
climbers, forming an exception in these respects to the
rest of the family. The bracts of A. hepatica are small,
three in number, and placed so close to the coloured
calyx that they might easily be mistaken for sepals were
it not that on pulling them off they are seen to be situated below
the thalamus and on the peduncle. In several other species, e.g.,
A. pulsatilla, the peduncle elongates after flowering, and separates
the fruit by several inches from the involucre of bracts. In Eran¬
this the involucre also looks like a calyx, only that the bracts are
divided, and there are both sepals and petals in addition. In
Helleborus faetidus there is a gradual transition from the leaves to
the bracts, the petiole becoming dilated and the lamina reduced
until the upper bracts consist of nothing but the dilated petiole.
Nature here reveals why the bracts of Helleborus niger differ so
much in shape from the leaves. In H. viridis, on the other hand,
the bracts consist of the lamina reduced in size, the petiole not
being developed at all.
In Clematis there are no bracts and no petals, only a coloured
calyx. The calyx in Eranthis, Anemone, Helleborus and Clematis
forms in each case the conspicuous and coloured part of the
flower, but in Ranunculus the calyx is small and inconspicuous.
In R. ficaria the petals have a triangular scale or nectary which
secretes honey, in Eranthis this scale is enlarged so as to form a
semi-tubular petal, and in Helleborus a tubular petal, the petals
being reduced in size, and almost hidden by the stamens. In
Anemone and Clematis petals are not developed. In Ranuncuhis
the fruit consists of achenes (one-seeded indehiscent carpels) which
in Anemone pulsatilla and some other species, as well as in Clematis,
are furnished with long hairy tails, but in Eranthis and Helleborus
each carpel contains several seeds, and opens when ripe, thus
forming a follicular fruit. In all the above plants, however, the
apocarpous ovary and numerous hypogynous stamens character¬
istic of the order may be observed. The development of two of
the petals into spurred nectaries in Aconite, and of five into
spurred petals in Aquilegia, may be observed in May, when the
other common abnormal flowers of this order can be examined.
NOTES ON THE B.P.
( Continued from page 150. )
Bxsmuthum Purificatum. — The solution in nitric acid evapo¬
rated to a low bulk deposits crystals of normal bismuth nitrate,
Bi3(NOa). The impurities remain almost entirely in the mother-
liquor, which should yield no evidence of arsenic when Marsh’s test
is applied. It is evaporated with hydrochloric acid to remove
nitric acid, which would interfere with some of the subsequent
tests. Any copper, silver, lead, or iron occurring as impurities
would then be in the form of chlorides together with bismuth
chloride and excess of HC1. On adding ammonia to this, bismuth
hydrate would be precipitated, copper revealing its presence by
a coloration, due to the formation of a deep blue ammonio salt.
Silver chloride, which is soluble to some extent in strong hydro¬
chloric acid, is precipitated but redissolved by excess of ammonia,
and must therefore be looked for in the ammoniacal filtrate in
the usual manner — neutralisation of the ammonia by nitric acid.
Lead is detected .by the formation of insoluble lead sulphate when
diluted sulphuric acid is added, and iron by ferrocyanide of
potassium. Tellurium and selenium, two non-metals belonging to
the sulphur group, sometimes occur as impurities. They form
gaseous hydrogen compounds, H2Te and H2Se, analagous to H2S,
which possess a more intolerable odour even than sulphuretted
hydrogen. When bismuth salts containing these impurities are
administered, these hydrogen compounds — hydrogen telluride and
selenide — are formed in the stomach and impart to the breath of
the patient a most unpleasant odour. If present in bismuth,
tellurous acid, H2Te03, and selenious acid, H2Se03 (analagous to
sulphurous acid, H2S03), wrill be formed by solution of the impure
metal in nitric acid. On adding sodium sulphite to the 'acid
solution (after separating most of the bismuth nitrate and re¬
placing nitric by hydrochloric acid) the H2S03 formed reduces
the corresponding selenious and tellurous acids, selenium and
tellurium being thrown down in the elemental state, the former
as a red and the latter a black precipitate. The H2SO:4 is con¬
verted into H2S04 by the oxygen taken from H2Te03 and H2Se03.
Borax. — Boric anhydride B.203 resembles phosphoric anhydride
in combining with different proportions of water to form acids : —
(i.) B20h + H20 = 2HB02 (metaboric acid).
(ii. ) B263 + 3H20 = 2H3B03 (boric acid).
When boric acid is neutralised with an alkali we do not get the
normal borate, but water is eliminated, and a metaborate formed,
(i.) H,B03 + NaH0 = NaH2B03 + H20.
(ii.) NaH2B03 = NaB02 + H2Ch
Borax may be regarded as a compound of sodium metaborate with
boric anhydride, (NaB02)2B20310H20, or metaboric acid (NaB02)2
(HB0.2)29H20. When solution of borax is treated with a strong acid,
normal boric acid is formed, the metaboric acid taking up water : —
hbo2+h2o = H3B03.
The use of borax beads in qualitative analysis is due to the
fused borax containing metaboric acid or anhydride. When a
metallic salt is fused in a borax bead, on platinum wire, the boric
anhydride being non-volatile, displaces the acidulous radicle with
which the metal was combined, and forms with the resulting oxide
compounds which have a distinctive colour in the following cases :
cobalt, copper, chromium, iron, and manganese.
Calcii Carbon as Precipitata. — If alumina or ferric oxide be
present the carbonate dissolved in nitric acid will contain
aluminium and ferric nitrates as well as Ca2NO_. Addition of
solution of lime will then precipitate Al26(IIO) or Fe.,6(HO). The
carbonic acid must be previously expelled by boiling, or a precipi¬
tate of calcium carbonate will be obtained.
• Ca2HO + C02 = CaC03 + H„0.
Calcii Phosphas. — Absence of effervescence when dissolved' in
nitric acid shows absence of carbonate. On adding excess of
sodium acetate, to replace free nitric by acetic acid, oxalate of
ammonium precipitates oxalate of calcium and perchloride of iron
ferric phosphate. Entire solubility in dilute hydrochloric acid
excludes silica, and the phosphate of calcium re-precipitated by
ammonia should be insoluble in caustic potash (alumina is soluble)
and weigh nearly the same as the original quantity taken.
180
PHARMACEUTICAL JOURNAL.
[Feb. 27, 1897
THE PHARMACEUTICAL SOCIETY’S BENEVOLENT FUND.
LETTER FROM THE PRESIDENT.
To the Editor oj the Pharmaceutical Journal.
Sir, — The Benevolent Fund of the Pharmaceutical Society forms
the prominent feature in the present issue of the Society’s Journal,
which will be sent to everyone on the Register of Chemists and
Druggists. The decennial festival dinner in support of the Fund
will be held in May, and I therefore venture to advocate its claims
upon all who are in any way associated with the practice of phar¬
macy. There is little doubt that during the present year,
The Diamond Jubilee of Our Queen,
appeals in support of many deserving objects will be made to every
class of Her Majesty’s subjects, but I hold that no object more
worthy of the support of pharmacists could be brought prominently
under their notice during this eventful year. I may also remind
my friends that the votes for donations made by firms in 1887
lapse this year. No department of the Society’s work is more
generally approved by all registered persons than that of
The Benevolent Fund,
though the pecuniary support hitherto received is inadequate, and
far below what might reasonably be expected. Criticisms there
are from time to time as to some of the details connected with its
administration, but I venture to affirm that there is no fund which,
judged by the infinitesimal expenses attaching to its management
as well as by the care and catholicity of its distribution, is more
worthy of hearty and ungrudging support. The Council cordially
appreciates the loyal and persevering efforts to increase the
resources of the Fund which are made by local secretaries and
others, and we hope that during the present year those efforts will
be crowned with more than usual success. I trust that our more
wealthy friends will continue their support by liberal donations on
the occasion of
The Approaching Festival,
and that all will contribute to the best of their power. Appeals
for local objects will be specially prominent this year, but let the
Fund, established for the aid of our distressed comrades, have a
good share of our liberality. It must not be forgotten that whilst
many appeal? are rightly addressed to and may be reason¬
ably supported by all classes of the community, the claims of our
Benevolent Fund, which exists exclusively for the benefit of
chemists and druggists, can be urged upon those only who
directly or indirectly are associated with our calling. The most
satisfactory way of assisting the Fund is to give
An Annual Subscription,
and I would specially appeal to my younger brethren, assistants,
apprentices, and students to make it a matter of duty to send an
annual contribution, however small at first, and to continue that
habit unasked and with regularity. It is unnecessary for me here
to refer in detail to what has been done in the past to lighten the
burdens of our less fortunate brethren or their representatives, as
such information may be obtained from other columns in the
Journal or from the Calendar of the Society. The record of the
good work accomplished by our Benevolent Fund is one in which
all contributors may feel gratification ; let us endeavour to make
it still more worthy of our Society and of our common calling.
17, Bloomsbury Square, W.G. Walter Hills.
February %/f., 1897. President.
THE SPECIAL APPEAL FOR THE BENEVOLENT FUND.
DONATIONS AND SUBSCRIPTIONS.
In response to the admirable suggestion of the local secretary
for Manchester, which appeared, in our correspondence columns on
p. 99, the Council of the Manchester Pharmaceutical Association
unanimously resolved, at a meeting held last week,
“That, as a fitting way of commemorating the completion of
the sixtieth year of the reign of Her Most Gracious Majesty the
Queen, this Council forms itself into a local committee (with power
to add to its number) for the purpose of obtaining a large increase
of subscriptions and donations to the Benevolent Fund of the
Pharmaceutical Society.”
Every member of the Council subsequently promised permanent
Increased subscriptions or a donation— in no case less than double
last year’s subscription.
It was further resolved —
“ That Mr. Harry Kemp be appointed to act as Secretary of
this Committee.”
As a practical way of beginning operations, each member pre¬
sent promised a donation or an increased annual subscription to
the Fund — in every case equal to or more than equal to double
his last year’s contribution.
Up to the time of going to press we had received notice of the
following donations, distinct from and in addition to the usual
annual subscriptions
£ s. d.
Bates, F. W . 1 1 0
Blackburn, A. E . 1 I 0
Blyton, Jno . . . 0 10 6
Carter, W . 0 10 6
Gibson (Robt.) and Sons . 5 5 0
Johnstone, Chas. A . 5 5 0
Kemp, H . 1 1 0
Lane, Wm . : . 1 1 0
Pidd, A. J . 1 1 0
Reynolds, R. J . . . 1 1 0
Westmacott, G. H . 1 1 0
Wild, Jno . . . 0 10 6
Woolley, Geo. 8 . 10 10 0
Woolley, Herman . . 10 10 0
Yates, E . 0 10 (i
Kirkby, Wm . 1 1 0
Young, J. R. . . 1 1 0
Howie, W. L . „ . 10 10 0
£53 11 0
The following have permanently doubled, or more than doubled,
their previous annual subscriptions to the Fund : — Swinn, Chas. ;
Travis, H. A. ; Walton, J. W.
Further lists will be published as particulars come to hand, and
it is hoped that other districts will follow the good example set by
Manchester.
Feb. 27. 1897 ]
PHARMACEUTICAL JOURNAL.
181
Pharmaceutical Journal.
A Weekly Record of Pharmacy and Allied Sciences.
ESTABLISHED 1841.
Circulating in the United Kingdom, France, Germany,
Austria, Italy, Russia, Switzerland, Canada, the
United States, South America, India,
Australasia, South Africa, etc.
Editorial Office: 17, BLOOMSBURY SQUARE, W.C.
Publishing and Advertising Office : 5, SEtyLE STREET, W.C.
LONDON : SATURDAY, FEBRUARY 27, 1897.
THE BENEVOLENT FUND.
In calling attention to this result of British pharma¬
ceutical organisation, which has been so long a means of
affording useful assistance to many deserving persons, little
can be said that has not already been repeatedly stated on
similar occasions. In every occupation misfortune will
befall some of its members and opportunity will be afforded
for a practical application of the principle that every man is a
■debtor to his calling. The business of the chemist and druggist,
in all the varied modifications determined by locality, is no
exception to the rule, either as regards the contingency of
disaster, or the duty of providing relief which falls upon
those who are more fortunate. Hence the establishment of a
Benevolent Fund was naturally one of the great objects con¬
templated by the founders of the Society as desirable features
of the pharmaceutical organisation, that was confirmed, more
than half a century ago, by the grant of a Royal Charter of
Incorporation.
Since that time, the beneficent influence of the Fund has
been extended, so that all persons registered as Chemists and
Druggists sre as much entitled to receive assistance in case
of need as members or associates of the Society. The Bene¬
volent Fund has therefore a catholic character which should
commend it to every member of the trade and be regarded by
each one as constituting a claim to support. That this claim
has been freely recognised by many is evident from the fact
that the invested capital of the Fund, largely derived from
donations and legacies, now amounts to £28,647 2*'. 5 d. The
income from that invested capital, together with annual
subscriptions, amounting in 1896 to more than £1710, has
provided means for the payment of annuities aiid the
grant of money in cases of emergency, by which a vast
amount of good has been done. There are at the present
time no less than forty-five annuitants, most of whom are in
receipt of £50 a year, the total amount paid in that way last
year being £2232 10s., besides the grants for temporary assist¬
ance amounting to £563.
But on comparing the list of subscribers to the Benevolent
Fund with the Register of Chemists and Druggists, there is
-evidence that the number of subscribers is far from being so
large as the inherent merits of the Fund should secure. In
view of this circumstance, the President has this week
made a special appeal to all members of the trade, setting
forth the reasons for making the Benevolent Fund a matter
of general and continuous support. Mr. Walter Hills’
letter will be found on the opposite page, and we commend
it to the careful consideration of every one who will this
week receive the Journal. As anticipating the response to
this appeal that may be expected from all parts of the
country, we have also great pleasure in drawing attention
to the substantial result of efforts made by Mr. Harry Kemp,
the Local Secretary for Manchester, in pursuance of the
scheme recently suggested by him (see ante, p. 98), which
was supported for Glasgow and Liverpool by Mr. Currie and
Mr. J. Smith (see ante, p. 119). The letter in which the
local secretaries of these three cities appeal to their colleagues
to follow up the beginning already made by Manchester, by a
personal appeal at every place of business in their several
localities, ought to furnish any stimulus that may be requisite
for making a very considerable addition to the resources of
the Benevolent Fund and we hope to be able next week to
publish corresponding lists from Glasgow and Liverpool.
INDIVIDUALISM AND SOCIALISM IN PHARMACY.
Civilised man is both an individual and a social being and
at his best probably represents a happy mean between
individualism and socialism — two apparently irreconcilable
tendencies. For to be of the utmost value as a unit of
society a man must develop as an individual to the fullest
possible extent, while the status of the social body in turn is
regulated by the average individuality of its members. As
the Dean of Ripon has recently pointed out, the social
unit — whether nation, municipality, or parish — should do
whatever it can do better than the individual ; whilst the
latter ought to be left to do whatever he can accomplish best
by himself. Where the line is to be drawn between indi¬
vidualistic and socialistic action must, of course, be deter¬
mined by the needs of the particular case. No hard and
fast rule can be laid down in this matter, as circumstances
will necessarily shape themselves differently under varying
conditions.
In the case of pharmacy it is not difficult to decide where
the dividing line, or perhaps it would be better to say the
blending point, is situated. The education and business
training of the individual are essentially matters for that
individual himself to look after primarily. But as develop¬
ment proceeds it clearly becomes the duty of the social unit
— the whole pharmacentical body in the present instance —
to encourage the acquisition of satisfactory education and
technical training by providing proper facilities to that end
and deciding within what limits instruction should be im¬
parted, a fixed minimum being the basis of any scheme that
may be carried into effect. Just, however, as a horse may
be dragged to a pond but cannot be compelled to drink,
so the acquirement of knowledge is primarily vested in
the individual chiefly concerned. The same is the case
with regard to the improvement of business capacity and, so
far as concerns the maintenance of existence, the normal
individual must invariably be dependent upon his own
efforts throughout his career : the exceptionally endowed
individual may thus secure and maintain an enviable posi¬
tion unaided, except indirectly, by the social fore es atwork
around him.
But in pharmacy, as elsewhere, the average individual must
needs rest content with few or only minor advantages,
unless he takes part in one or more of those movements of
aggregation by which the activity of the social spirit is con¬
tinually being manifested. And his privileges may be ex¬
pected to increase, his position to improve, in proportion to
[Feb. 27, 1897.
1-8&-
PHARMACEUTICAL J0UAL.N7I
the unanimity with which the social movements in which
he takes part are supported by other individuals who are
similarly situated to himself. To take as an example the
Pharmaceutical Society — the only survivor of the various
political and social movements that have from time to
time agitated British pharmacy — it has been able
to maintain an unbroken and successful existence
for more than half a century, simply because of the
unanimity with which a majority of the best educated indi¬
viduals in pharmacy have supported it.
The position of the craft would have been vastly inferior to
what it is to-day had not the Society or some kindred body
existed to represent it in emergencies and protect its privileges
in times of danger, whilst steadily keeping in view the
elevation of the social unit and striving continually to main¬
tain it in the front rank as an organised body. "What
more might have been done, had the Society been fully
instead of partially representative of the craft during bygone
years, can only be conjectured ; but this much is clear, that it
rests with the chemists and druggists of Groat Britain at
the present day to enable it to accomplish many things
that are yet to be achieved. To strive after wrhat is
clearly unrealisable would be absurd ; but to neglect oppor¬
tunities of securing what is feasible in the way of worldly
advantage is folly, and all who have the good of phar¬
macy at heait should continue to hope and work together
that lost ground may be recovered and fresh positions won
by securing the adherence and active sympathy of those who
yet remain outside the ranks of the Society.
TBE PURITY OF FOOD AND DRUGS.
We have been favoured with a copy of the Bill to con¬
solidate and amend the law relating to the sale of food and
drugs, which has been prepared and brought in by Mr.
Kearley, Sir James Woodhouse, Mr. Horace Plunkett,
Mr. Lambert, Mr. Jeffreys, Mr. Nichol, Mr. Channing,
Mr. Lough, and Mr. Maurice Healy. In this Bill the term
“ drug ’’ is defined to mean “ any substance, vegetable, animal
or mineral used in the composition or preparation of medicines,
whether for external or internal use,” and it is proposed that
every conviction for an offence under the “ Act ” shall carry
with it a penalty “ not exceeding twenty pounds ” for a first
offence, “ not less than five pounds and not exceeding fifty
pounds ” for a second offence, “ not less than twenty pounds
and not exceeding one hundred pounds ” for a third or subse¬
quent offence, an alternative in the last-mentioned case, in the
discretion of the justice hearing the case, being “imprisonment
with or without hard labour for a period not exceeding three
calendar months.” Further, where any person is convicted of a
second or any subsequent offence against the “ Act,” it is
proposed that the court or justices before whom such person
is convicted, may, in addition to any penalty inflicted under
the preceding section, order that “ a notice of the facts
be affixed in such form and manner and for such
period, not exceeding twenty-one days, as the court may
order, to any premises occupied by that person,” such facts
to be also advertised in newspapers, and the person con¬
victed to pay all costs. Detailed reference to the Bill must
be deferred, but it may be mentioned that the appointment
of a Board of Reference is suggested, upon which shall be a
person nominated by the Pharmaceutical Society. Local
pharmaceutical associations will do well to devote a little
consideration to this Bill.
ANNOTATIONS.
A Record Number of the Journal was aimed at in the prepa¬
ration of this special issue — which has a larger circulation than
that of any other paper addressing the chemists and druggists of
Great Britain — and we trust that readers will appreciate the efforts
which have been made. The hearty co-operation of numerous
friends has enabled us to produce a copy of the Journal which
should appeal to everyone in pharmacy, whether mainly interested
in the professional or the trade side of the craft. Students young
and old are here catered for no less than practising pharmacists,
and matters of direct interest to the busy tradesman receive equal
attention with those that especially attract the scientific pharmacist.
The Students’ Page has this week doubled itself, and this
opportunity may be taken of stating that the communications
received respecting the notes and short articles that are being
published under that head reveal the fact that current text-books
for pharmaceutical students are sadly lacking in essential details.
We have fortunately been able to supply a crying need, and
rejoice accordingly. Advanced students also receive attention in
this number, the series now commenced on “Practical Pharmaco-
graphy ” being especially designed to supply information not
readily attainable by students at present. Notes explanatory of
familiar and yet comparatively unknown operations in analytical work
will appear later, together with articles on such difficult points in
other subjects as may be found by experience to require explanation.
The Proprietary Articles Trade Association once more has
its case stated (p. 168), on this occasion by Mr. William Johnston,
the Assistant-Secretary. The article by Mr. Glyn-Jones, which
appeared in these pages a few weeks ago (ante, p. 23), was inserted
in order that many chemists and druggists throughout the country,
who were somewhat in the dark about the anti-cutting agitation,
might have the matter placed fairly before them. The advantage
of that step has been fully proved, and on the present occasion it
is believed that many others who are directly interested in the
movement will learn for the first time exactly what the P.A.T.A.
is, and is doing. It is very necessary that everything affecting the
interests of chemists and druggists as a body should be clearly
understood by all, and with that idea in view a considerable
amount of space has been devoted to the proceedings of the
P.A.T.A. for some time past.
The Opposition Case is stated (p. 169) by Mr. John Ingham,
of Upper Tooting, who recently contributed an excellent letter
(ante, p. 139) on the subject. The views he advocates are those
held by many thoughtful pharmacists, and therefore deserving of
every consideration at the hands of the leaders of the New Crusade.
We purposely abstain from comment on the opinions expressed on
either side, in the belief that the matter is essentially one for
careful consideration and settlement by retail chemists and drug¬
gists— the parties chiefly interested. But on one point it is quite
safe to speak, and that is with regard to the remarkable outburst
of interest taken in this absorbing topic locally.
Local Pharmaceutical Associations have been powerfully
affected by the activity, of Mr. Glyn-Jones and his colleagues, and
if no other permanent result be attained but the awakening of a
spirit of union in numerous centres all over the country, a useful
purpose will have been served. Active associations have been
excited to renewed exertions, passive ones rendered active, and
Feb. 27, 1897]
PHARMACEUTICAL JOURNAL.
183
moribund ones endowed with a new lease of life, whilst in several
centres where pharmaceutical associations formerly did not exist;
that lack is now supplied. An article by the Secretary of the
P.A.T.A., showing the extent to which local associations have
profited by the consideration of the latest economic problem in
pharmacy is unavoidably deferred for publication later.
“A Druggist’s Misfortune,” the Bournemouth newspapers
head their reports of a very unusual incident which occurred last
week, at the sitting of the Bournemouth County Court, under
Judge Philbrick, in the Boscombe Assembly Room. It appears
that during the hearing of a case his Honour was interrupted by a
loud and continued knocking just underneath the windows of the
room in which the Court were sitting, and the Judge at once sent
a bailiff of the Court to warn the persons creating the nuisance to
stop. This was done, but the knocking was re-commenced in a
few minutes and, losing patience, the J udge sent for the delinquent,
a lad who had been hammering the blind-irons attached to the
front of the Southern Drug Co.’s shop. As he proved to have
acted under the instructions of the manager, that individual was
in turn sent for and threatened with forty-eight hours’ imprison¬
ment. After being kept in the Court for a short time, however,
the judicial heart relented and, after promising not to do it again,
the unlucky manager was permitted to depart.
The Idea of a National Physical Laboratory is not viewed
with much favour by the Times, which commends Lord Salisbury’s
expression of opinion that the best way to approach the Chan¬
cellor of the Exchequer is not by expatiating upon the magnitude
of the field opened up to the State, wThen once it embarks upon
pure research, but by pressing upon it the duty of some concrete,
practical and definitely measureable extension of functions which
it already discharges. The suggestion that the State should
undertake the systematic accurate determination of physical con¬
stants, etc., is happily described as our old friend, “ the endow¬
ment of research, alias the research of endowment,” in its most
audacious form, which is ‘ ‘ as bad for science as it is for the
State.”
Professor Rucker, who talked much of what is done in Ger.
many, is accused by the Times of following the example of most
people who deal with this question, and taking from the German
system j ust what suited him. It is insisted that Germany does
not endow research in the manner contemplated here, and only
stimulates, encourages, and rewards original investigations on a
practical basis and as the outcome of practical success. “ Germany
does not build national laboratories in the void and set men to
look for things that £ may be useful ’ when people are taught
them.” No ! She begins at the beginning, training her manu¬
facturers and organising her universities upon a thoroughly
practical system which is in touch at every point with the com¬
mercial needs of the people. National laboratories are set up later,
“to co-ordinate and harmonise private and public efforts, to supply
wants which are actually felt, and to give information specially
demanded.”
British Universities, it is contended, do not turn out the right
sort of men, and our manufacturers do not demand the right sort
of information. The universities cram men with book knowledge,
and test it by everlasting examinations. As a result they turn
out pedagogues very competent to cram and examine in their
turn, but possessing neither ability nor inclination to deal with
the application of science to affairs. In Germany, on the other
hand, science training deals with things, not only with books, it
places its men according to the ability they display in conducting
actual investigations and solving practical problems for themselves.
When those men leave college they gladly enter the laboratories of
manufacturers, where they are entirely at home and immediately
useful, and manufacturers are equally glad to have them, and to
pay them for research conjoined with practical direction of existing
processes. It is not to be wondered at, therefore, that British
manufacturers who try book-made men of science find them upon
the w'hole of less use than intelligent foremen, and we are forced
to the conclusion that, if Germany be really pushing us out of
markets in which success depends upon the continuous application
of science to affairs, the reason is, as recently stated in this J ournal,
“ lack of enterprise, disinclination to depart from old-fashioned
habits, unsatisfactory business methods, and support of fads.”
Mr. George Herbert Murray, C.B., who succeeds Sir Alfred
Milner as Chairman of the Board of Inland Revenue, on the
appointment of the latter as High Commissioner for South Africa,
has been for some time past a principal clerk in the Treasury. He
has also served in the Foreign Office, as secretary to the Commis¬
sion for negotiating a new commercial treaty with France, and as
secretary to the Royal Commission on Trade (1885), in addition to
acting as private secretary to Sir Charles Dilke, Mr. Gladstone,
and Lord Rosebery.
Carbolic Acid Tempers Steel Tools, according to the
Engineer, which quotes from a French source. M. Levat, who re¬
commends its use for this purpose, tempered one cold chisel in
water, and another in a solution of carbolic acid, after both had
been heated to a cherry red. The chisels were then set to work on
extra hard wrought iron, and it was found that the one tempered
in water became notched after a short time, whilst the one
tempered in carbolic acid remained perfectly intact. A second
test was made with two puddled steel bars, which were heated to
white heat and tempered in water and carbolic acid respectively.
The bar tempered in carbolic acid showed a much finer fracture,
which reflected like a mirror when filed, and its carbon contents
were not increased, butinthe bending test itshowed more elasticity
and pliability than the other, while its hardness made it more
suitable for tools.
An Institute for Teaching Botany is badly needed in London,
and it is satisfactory to find that there is some hope of such an
institute being established in connection with the Royal Botanic
Gardens. Mr. William Martindale is taking a characteristically
active part in urging the claims of London to possess a Botanical
Teaching Institute, and there is little doubt that the Royal
Botanic Society will establish itself more firmly and show a better
reason for its existence, if it lends its aid to the furtherance of the
scheme to be proposed at the meeting on Saturday afternoon. In
connection with this matter Mr. W. Harrison Martindale’s description
of the Botanical Institute and Garden at Marburg (see p. 174)
possesses especial interest. In this direction, as in some others,
Germany leads the way, and perhaps for once it might be well,
as Mr. William Martindale urges, to copy German methods.
The Chemists’ Assistants’ Association holds its nineteenth
annual dinner on Thursday next, March 4, the place of entertain¬
ment being the King’s Hall, Holborn Restaurant, and the time
8 p.m. Mr. Charles Morley, President of the Association, will
take the chair, and is promised the support of a number of pro¬
minent pharmacists and medical men on the occasion. Mr. A. R.
184
PHARMACEUTICAL JOURNAL.
[Feb. 27, 1897
Melhuish, one of the honorary secretaries of the dinner committee,
writes to say that the committee has arranged a good musical pro¬
gramme, and is sparing no efforts to ensure a successful and enjoy¬
able evening. He also asks that those who have not yet secured
tickets should be reminded that they may obtain them by apply¬
ing to any of the stewards.
“ Electrical Currents in the Human Body” was the subject of
an interesting lecture at Toynbee Hall, by Professor Victor
Horsley, on Saturday last. The lecturer pointed out that the man
to whom we are most indebted for the practical application of
electricity — at any rate of being the discoverer of the fundamental
principles — was Michael Faraday, who was not a physiologist, but
dealt with the phenomena of electricity in dead materials,
such as metals. Professor Horsley then proceeded to explain,
by means of a few simple experiments, the actual position of
affairs with regard to the existence of electricity in the
living body. Owing to ignorance, he said the subject had un¬
fortunately been selected by fraudulent quacks in order that they
might the more easily plunder their victims. Apart from this,
however, although the subject had not yet been anything like
mastered, still the vast amount of progress which had been made
in connection with it during the last few years, demonstrated to
the full that the study of electricity in the human body will occupy
an important part in medical science in years to come.
The Universal Trade Association is an anti-cuttng organisa¬
tion, having its headquarters in Detroit, Mich., U.S.A. It is
described as a corporation consisting of retail druggists for the
purpose of manufacturing and selling “patent labels,” to be
employed on proprietary preparations. The control of these labels
in the United States is to be delegated to an association of retail
druggists, called the United Trade Society, which is to be
empowered to carry into effect the plan devised to prevent cutting.
Thus, it is proposed that manufacturers shall purchase the labels,
which are numbered consecutively, and attach them to their pack¬
ages. The profits arising from the sales of the labels are to be divided
amongst the druggists, and the system is to be worked by a
central bureau. Any goods bearing the labels found in the pos¬
session of cutters may be “ taken up ” by agents of the Society
nd returned to the manufacturer, who must redeem them.
Finally, the Society will from time to time publish the names of
all manufacturers and wholesalers supporting it. The best that
can be said of this plan is that it is ingenious ; the worst, that it is
too complicated to be workable. Indeed, it appears doubtful
whether anyone striving his utmost to devise the most involved
system possible could have excelled the organisers of the U.T.A.
in ingenuity.
Ammonium Sulphocyanide is not Poisonous. — According to
Dr. Heffter, who has tested the sulphocyanide used in photography
for its alleged toxic properties, and has declared them absent.
On the Continent, observes the Photographic News, one of the
chief reasons for what Dame Quickly terms “ an old abusing of
God’s patience and the King’s English ” is the perverse manner in
which foreign druggists refuse sulphocyanide of ammonium for
the toning bath, “ because it is a poison.” As might
have been expected from a careful German savant, Dr.
Heffter proceeded cautiously, experimenting at first with animals
before testing the substances on his own body. Cats and
rabbits had various sulphocyanides injected in large doses into the
blood and introduced into the stomach, and as they took
no harm Dr. Heffter boldly and safely swallowed a gramme of
ammonium sulphocyanide. Of course, the experiments were con¬
fined to the sulphocyanide ordinarily used in photography, and did
not extend to the sulphocyanides of lead, barium and mercury,
which, containing for their base metals noxious to human health,
are more or less poisonous.
The Decennial Festival Dinner in aid of the Benevolent Fund
will be held at the Hotel Cecil, Strand, W.C., on Tuesday, May 18,
1897. It will take the place of the usual dinner of the members of
the Pharmaceutical Society and their friends, and the chair will
be taken by Mr. Walter Hills, the President of the Society. A
preliminary list of Stewards will be found in our advertisement
pages, and we are desired to state that the Committee will be glad
to receive the names of any gentlemen who may be willing to act
in that capacity. The liability of each Steward on this occasion is
limited to the price of one dinner ticket, and inability to attend
need not prevent anyone from guaranteeing to contribute a guinea.
Indeed, the more people who purchase tickets and do not attend
the dinner the greater will be the extent to which the Fund will
benefit. Mr. Richard Bremridge will be glad to receive applica¬
tions for tickets at 17, Bloomsbury Square, W.C.
A Picture of American “ Pharmacy” is given by the Bulletin,
of Pharmacy, which describes how an enterprising New York
druggist has recently purchased a third store, of which he
proposes to make a first-class pharmacy. These are a few of the
enticements he is about to offer the public : Telephone, messenger
service, postage stamps, private letter boxes, American express
money orders, American express call, carriage call, theatre ticket
agency, Journal and World advertisements, time-tables, bulletin
guides, etc. This, it is observed, is broad-gauge enterprise, and
the question is asked whether it is deserved by the public ?
The X Rays can now penetrate through any diameter of the
throat and abdomen, according to an article in the Deutsche Medi~
cinische Wochenschrift, describing experiments carried out by
Doctors Schjerning and Kranzf elder in the medical section of the
German War Ministry. Hittorf tubes, constructed for sparks of
15 to 20 Cm. length, were employed in the experiments, and less,
perfect images were obtained by passing the X rays in the direc¬
tion of the transverse diameter of the chest and the pelvic basis.
The exposure was comparatively short, but this was due more to>
the greater intensity of the rays than to an increase in the sensi¬
bility of the plates. Exposures of twenty and thirty minutes
sufficed for the skull and the pelvis, whilst radiographs of the hand
required only half a minute to two minutes, and those of the-
elbow and the leg joints from two to ten minutes. The fluorescent,
screen employed allowed the movements of the heart and
diaphragm to be observed.
A Fluorescent Screen, combining the maximum of efficiency'
with the minimum of cost, has hitherto been a great desideratum
in X ray work. Tungstate of calcium is low in price, but pos¬
sesses the disadvantage of low efficiency, and better fluorescent
substances, like barium and potassium platinocyanide, are expen¬
sive. Dr. Melckebeke, however, recommends the double fluoride
of ammonium and uranium (Ur202Fl24 NH4F1), obtained by pour¬
ing a solution containing one part of ammonium fluoride into one
containing two parts of uranium nitrate. The crystalline deposit,
formed is washed writh cold water on a filter and dried. The
brighter fluorescence of this compound permits of a considerable
curtailment of the exposure ordinarily required for the X rays, and
by the use of screens coated with the double fluoride, one experi¬
menter, using ordinary appliances, has been able to reduce the ex¬
posure from sixty to five minutes in radiographing the human luuu/d.
Feb. 27, 1897]
PHARMACEUTICAL JOURNAL.
185
LITERARY NOTES.
In ‘Tutorial Chemistry’ (Parti., Non-metals), by Dr. G. H.
Bailey, the treatment adopted by the author differs somewhat from
that adopted in most elementary text-books on the same subject ;
and on examination one finds in this evidence that the writer, from
his own standpoint, is endeavouring to meet deficiences in existing
elementary text-books. The book impresses one as having been
written by a teacher in personal contact with beginners, on account
of the endeavours made in many places to explain difficulties
which constantly afflict the chemical tyro. One is very glad to
find proofs constantly given for the formulae used for the various
substances dealt with, as well as direct experimental proof
in concrete form. The chapters on Air, Waters, and Fuels maybe
particularly commended for the interesting material they contain,
and cannot fail to interest the student by showing him how a know¬
ledge of chemistry furnishes an explanation of many of the pheno¬
mena of his daily life. A useful chapter is given at the end on
Chemical Calculations, in which, among other things, the reciprocal
relation of the volume of 1 gramme to the weight of 1 litre of hydro¬
gen is clearly set forth, showing the student how he should use the one
or the other constant, according to the nature of the problem to be
solved. The desirability of this is so obvious that one is surprised to
find how seldom the explanation is given in elementary works. The
information given in the book is accurate, and written in a clear
and easy style. We have, however, noted an obvious misprint on
p. 62 of ferrous sulphide for NiS, and on p. 152 the error that
“Bone-ash is obtained by the dry distillation of bones.” The
term sulphate of lime is used in several places, and no mention is
made of the origin of the metre, only its equivalent in inches being
given.
* The Progress of Medical Chemistry,’ as described by Dr.
J. L. W. Thudichum in a reprint of articles published
in the M ediccU Press, is somewhat unintelligible to ‘ ‘ mere
chemists.” Having read the book, one can hardly feel
that chemistry would have progressed less had it never been
written. The analysis of various gummy precipitates produced by
the addition of such reagents as lead acetate to various animal
fluids seems to have furnished Dr. Thudichum with opportunities
for constructing empirical formulae, from which he derives
much satisfaction. Certain other persons have, however,
objected to these, but Dr. Thudichum dismisses these
people (p. 27) as “ mere chemists who .... make demands
which, if accepted, would make any effectual study of biological
chemistry impossible.” It is evident, therefore, that the “mere
chemist ” is not wanted, since it appears that he is inconveniently
particular concerning the purity of substances he subjects to
analysis. To make this clearer, Dr. Thudichum avoids terms used
in common chemistry as much as possible. For instance, on p. 89,
we have: “The polybenzoylic esters are the more labile, the spano-
benzoylic esters however, the less deciduous chemical compounds,”
and Chapter VII. is devoted to some derivatives of “ New Emunc-
tory Cohols.” With regard to these it appears (p. 89) that “during
chemolysis with soda a portion of urochrome ester becomes at last
quite insoluble in boiling alkali ; it is not changed. It is thus
seen that as the research progresses it increases in complication ”
—a conclusion with which everyone will agree. Another
peculiarity of Dr. Thudichum is the use of the term “ Atomic
Weight ” for what is commonly regarded as “ Molecular Weight”
— thus the atomic weight of the substance C4H7N30 -2H20 is 149,
and of another C70H140N2Oa, 1216. The contents of the book are
mainly contentious, largely personal and monotonous to read : the
monotony is relieved, however, by an occasional incursion into the
domain of “ Punch.” For we find Chapter IX. devoted to “ Sup¬
posed Carbohydrates as supposed sources of fatty Acids from
Urine, and a New Mode of obtaining an unearned Increment of
Literary Reputation by Mock Research ” ; and Chapter XVI. to
“ A Shady Side of Biological Science — the Ghosts of Spurious Re*
searches,” which affords some illustration of the fertility of brain
in material as well as psychic products.
‘ Memoranda ’ is the modest and unpretentious title of an ex¬
cellent little book published by Messrs. Hearon, Squire and Francis,
of 38, Southwark Street, S.E., at the price of two shillings. It
includes a well-arranged alphabetical list of remedies, “princi¬
pally ex-pharmacopoeial and new to medicine ” ; similar lists of
photographic chemicals, the doses and uses of unofficial drugs and
chemicals, animal preparations, antitoxin serums, select pharma¬
ceutical preparations, liquid extracts, and oleates. There are also
numerous tables embodying much useful information, a list of
medical terms, a capital index, and several blank pages for notes.
‘ Useful Notes for Everyday Practice ’ is a booklet on some¬
what similar lines, but compiled especially for the use of members
of the medical profession, by Messrs. Allen and Hanburys, Limited,
London. It contains articles on the treatment of disease by thera¬
peutic serums, and the therapeutics of animal extracts, together
with notes on dieting, etc., in various morbid conditions, informa¬
tion respecting poisons and their antidotes, and so forth.
‘The Medical Annual and Practitioner’s Index’ is a most
useful work of reference for medical men. It has now reached
its fifteenth year of publication, and contains more than seven
hundred pages, occupied for the most part by articles contributed
by leading practitioners. A therapeutic review of the past year
is followed by a handy dictionary of new remedies and a dictionary
of new treatment in medicine and surgery. Then come between
forty and fifty important articles on special diseases ; lists of new
inventions, improvements in pharmacy, and dietetic articles, par¬
ticulars concerning asylums, training institutions, homes of various
descriptions, societies, medical and scientific newspapers, etc., etc.
Altogether, it is a most conveniently arranged work, and one that
becomes more and more indispensable as years roll on. It is pub¬
lished by Messrs. J. Wright and Co., Bristol, at Is. 6 d. net.
‘ Herbal Simples Approved for Modern Uses of Cure,’ by
Dr. W. T. Fernie, has increased in bulk considerably since its
first publication, eighteen months ago, there being more than two
hundred extra pages in the second edition, just published. It is inte¬
resting to read in the preface to this edition the author s pleasantly
worded and amusing criticisms of the critics of the original work,
and satisfactory to find that “ certain botanical mistakes pointed
out with authority by the Pharmaceutical Journal have been duly
corrected.” To this extent, therefore, the book is now better than
it was before, excellent as it was at the outset, and it must be
added that descriptions are now included of fifty additional
simples. Beyond this, the author advances a higher claim than
has been made hitherto for the paramount importance of the:
whole subject. Without discussing this claim, it may be said that
the book is an excellent summary of the subject of which it treats,
and should be in the hands of everyone interested in that subject*
Despite the greatly increased size of the book, the publishers
Messrs. John Wright and Co., of Bristol— have produced the new
edition at a very slightly advanced cost, the price now being 6*.
186
PHARMACEUTICAL JOURNAL.
[Feb. 27, 1897
‘ Aid* to Bacteriology,’ by Messrs. T. H. Pearmain and C. G.
Moor, is small and compact, and altogether well adapted for what
may be regarded as its main object — that of serving as a primer
for the use of those who are entering upon the serious study o^
the subject. It will doubtless surprise many to find what a mass
of useful information is crowded into the one hundred and
fifty pages of this book, but it is also satisfactory to note
that the matter is well arranged and of an extremely practical
nature. The introduction constitutes a model essay on microbes and
their peculiarities, and this is succeeded by descriptions of the
apparatus and methods employed in bacteriological research,
together wdth details concerning the preparation of nutrient
media, in which superfluous words will be difficult to find. The
subsequent chapters deal with the methods of the spread of disease,
disinfection, immunity, etc. ; characters of the chief pathogenic
organisms ; micro-organisms other than bacteria ; products of the
metabolism of organisms ; the bacteriological examination of wrater,
air, and soil ; and the characters of some commonly occurring
pathogenic and non-pathogenic organisms not described in the
earlier chapters. F or medical students and chemists in particular,
therefore, here may be found bacteriology in a nutshell. The price of
the book is 3s. 6 cl. , and the publishers are Messrs. Bailliere, Tindall
and Cox, King William Street, Strand, London.
‘ Economic Plants,’ the valuable work on the useful plants
of the Dutch East Indies by D. M. Greshoff has reached its third
part. The plants, of which the botany, chemistry, and useful
properties are fully discussed, are Hernandia peltata, Meissn. ; Calo-
phyllum inophyllum, Linn. ; Eurycoma longifolia, Jack. ; Euchresta
Horsfiddii, Benn. ; Derris elliptica, Benth. ; Pterocarpus indicus,
Willd. ; Barringtonia speciosa, Forst. ; Styrax benzoin, Dryand ;
Ccesalpinia sappan, Linn. ; and Cedrela serrata, Royle. The illus¬
trations are life-size, andthe treatment is exhaustive, the most recent
publications in other countries having evidently been consulted.
‘Elementary Bandaging and Surgical Dressing’ is a book
that should need little to be said in its favour, since it has now
reached its seventh edition. Originally written by the late
Walter Pye, F.R.C.S., it has been revised and in part re-written
by Mr. G. Bellingham Smith, of Guy’s Hospitol. Concerning
bandages, splints, etc., and their application, the dressing of
wounds, burns, and scalds, and the treatment in the first instance
of accidents and emergencies, as much information is imparted
here as is likely to be required by all but surgical experts, and
even they might do worse than carry a copy of the book in their
pockets. It is profusely illustrated, and has been adopted by the
St. John Ambulance Association. It is published at 2s. by Messrs.
John Wright and Co., of Bristol.
‘ The Proceedings of the American Pharmaceutical Associa¬
tion ’ continues to be the best summary of the year’s wTork in
pharmacy and allied subjects, published in the English language.
That the excellent abstracts of papers continue to be regarded
as the most important part of this portly volume seems to be in¬
dicated by the fact that more than two-thirds of it is devoted to
them. Our American cousins are noted for their exceptional skill
in compiling and editing works of reference, and the Committee on
Publication of the American Pharmaceutical Association con¬
tinues to keep to the front in that respect.
‘ The Wonders of the Microscope,’ by Edward Poulson, is a
slight production of sixty pages, published by Messrs. Houlston
and Sons, Paternoster Buildings, E.C., at the nominal price of
fourpence. The author has attempted to combine the study of
theology and that of Natural History with but imperfect success.
PARLIAMENTARY NOTES AND NEWS-
The Patent Office still seems to be a legitimate target for
complaints, though it harbours no Deputy chaff- wax now, and the
days of the Hanapers are past. Captain Phillpotts (Torquay)
charges it with fostering foreign monopolies, and instances the case
of the trade in aniline dyes. The gallant captain is instructed
that a foreigner can, by taking out a patent in England, prevent a
process from being carried out in this country, .though he is under
no obligation to exercise it here himself. The result is that the
grant of letters patent in such a case is equivalent to the grant of
a monopoly — an open market in Great Britain, and no competition.
This is a very serious thing, and the thanks of the trading com¬
munity, and especially that portion of it engaged in the chemical
trade, are due to Captain Phillpotts for questioning the President
of the Board of Trade on the subject. In reply, reference was
made to Section 22 of the Patents Act 1883, as being all sufficient,
and the country must perforce put up with the hardship the
member for Torquay complains of, for there is no intention at the
Board of Trade to move for an alteration in the law.
Admiral Field, the hon. and gallant Member for Eastbourne,
has been much distressed to learn that a London theatre is offer¬
ing for the public entertainment a piece founded upon certain
amiable weaknesses of England’s greatest naval hero. In the
opinion of Admiral Field such entertainments are calculated to
bring the Naval Service into disrepute by holding up to public
derision the personality of famous officers. He therefore rebuked
the Lord Chamberlain for passing such a play, and asked whether
it was proposed to withdraw the licence now that the full gravity
of the case had been pointed out. Naturally, the question was
responded to by a direct negative, for the Public Censor had been
unable to find anything objectionable in the book of words sub¬
mitted to him. Thereupon the Admiral solemnly gave notice that
he would bring the subject up for further consideration when the
House came to deal with the Lord Chamberlain’s salary. One feels
impelled to ask whether the Society of Apothecaries or the Phar¬
maceutical Society might not, with equal show of reason, ask for
an injunction to restrain the production of “Romeo and Juliet” on
the ground that the art and mystery of medicine and pharmacy
embodied in the person of the apothecary in that tragedy is not
presented in a reputable light !
Calcium Carbide. — In reply to Mr. Kearley, the Home Secre¬
tary has given an assurance that the dangers attending the
storage and conveyance of this substance have been occupying the
serious attention of his Department for some months. As a result
of the consideration accorded to the subject by the Inspectors of
Explosives, it is intended to take advantage of Clause 14 of the
Petroleum Act, and apply, by an Order in Council, the provisions
of the Act to Carbide. It was intimated also that a memorandum
would be issued to local authorities suggesting the precautions to
be adopted for minimising the risk attaching to storage. No one
should be disposed to object to this substance being placed under
supervision, but it is a moot point whether the provisions of a
notoriously defective Petroleum Act will be quite effective when
applied in such a case. The Home Office Memorandum will be
awaited with some interest.
The Petroleum Committee has been practically re-constituted,
and will recommence its labours at an early date. The evidence
to be taken will chiefly relate to the construction of petroleum
lamps.
Feb. 27, 1897]
PHARMACEUTICAL JOURNAL,
187
IWEETIflGS Of SCIENTIFIC SOCIETIES
- » -
Chemical Society, Thursday, February 18. — Mr. A. G.
V ernon Harcourt, F. R. S. , President, in the chair. — The first paper
by T. S. Dymond and F. Hughes was on
The Oxidation of Sulphurous Acid by Potassium
Permanganate.
Experiments by the authors on this subject led them to believe
that there was something more than sulphuric acid produced on
oxidising sulphurous acid by potassium permanganate. The
apparatus used was that employed by Dunstan and Dymond for
the titration of nitrites, and as oxygen is a source of error,
the water used in all the experiments was boiled in order to
get rid of dissolved oxygen. A crystallised substance
was obtained from the oxidised solution after the removal
of sulphuric acid and manganese oxide. It was difficult to obtain
pure, but it was eventually proved to be an intermediate product,
viz., dithionic acid, S205. Further search for other products gave
negative results. It appears that in titrating sodium sulphite the
conditions of dilution, temperature, and acidity have no influence
whatever on the amount of permanganate volumetric solution re¬
quired for oxidation. Sodium sulphite, 0’4 gramme, was used in
every case, and it was found that the permanganate used remained
uniformly at about 18'8 C.c. Any slight difference in
some of the experiments was attributed by Mr. Dymond,
who read the paper, to oxygen, perhaps accidentally
present. Under certain conditions sulphuric acid only is
formed. The President referred to the influence of the oxygen
of the water, and also manganese sulphate in the process of
oxidation, and Dr. Alexander Scott, of the Davy-Faraday
Laboratory, inquired if manganic salts had been tried. Mr.
Dunstan also spoke.
Dr. Collie next followed with a paper on
The Production of Pyridine Derivatives from Ethylic-/3-
Amido Crotonate.
This was a paper dealing with the substances formed from aceto-
acetic ether, which condenses in all sorts of curious ways, and is
interesting as being the starting point of alkaloids. Many different
substances have been obtained from the amido compounds of aceto-
acetic ether, and acids have been produced by saponifying them,
two of the acids producing oxypyridine compounds. Dr. Collie
stated that the production of various isomeric bodies was one of
the chief points in his paper. Dr. Forster, after the reading of
the paper, placed a few formulas on the board, and drew attention
to an analogy which seemed to exist between some camphor
bodies and some of the substances described by Dr. Collie. This
was the thin end of the wedge for a little conversation on
camphor, and Dr. Kipping somewhat diffidently inquired if he
might be permitted to introduce a few words on the constitution
of this substance. After Dr. Collie’s reply a large proportion of
the audience withdrew to the coffee-room.
Mr. Dunstan was then called upon in the absence of the author
to read the paper on
SODAMIDE AND SOME OF ITS SUBSTITUTION DERIVATIVES,
by A. W. Titherley, M.Sc., Ph.D. He read it quickly as usual,
and in abstract. Sodamide, which has the formula NaNH2, was
described, as well as its action on certain oximes whereby a series of
sodium derivatives is obtained. Acetoxime and sodamide give
rise to this reaction : — -
(CH3)?CNOH + NaNH2 = NII:) + (CH3),CNONa.
Sodium benzamide and formamide can iikewise be produced. These
salts dissolve in alcohol, and with alcoholic solution of silver
nitrate produced silver salts. Further results will be communicated
later on.
Rubidamide,
by the same author, was also read. This substance is obtained by
heating rubidium in ammonia gas. Its composition was rather
difficult to determine, on account of its highly deliquescent nature.
The determination of the ammonia, however, shows that its formula
is RbNH.,. This substance has been compared with sodamide,
potassamide, and lithamide. The melting points stand thus
Sodamide, NaNH2 . 155° C.
Potassamide, KNH2 . 270°-272° C.
Rubidamide, RbNH2 . 2S5°-2S7° C.
Lithamide, LlNH2 . . 3S0°-400<J C.
Great difficulty was experienced in determining the melting point
of lithamide. Rubidamide is decomposed by water and also by
alcohol, and there is thus an exact parallel between the amides of
the alkali metals. — Mr. Bloxam and Dr. Rideal spoke. The last
paper read was “ On the Spectographic Analysis of Some Com¬
mercial Samples of Metals, of Chemical Preparations, and Minerals
from the Stassfurt Potash Beds,” by W. N. Hartley, F.R.S., and
H. Ramage. This is a continuation of work already done speci¬
fying the metals found spectroscopically in earths and commercial
metals. Alkali metals, etc., are present in steel, but chromium
and nickel are removed in the process of manufacture. The authors
prove, and they took particular care to do so, that the various
elementary impurities in the substances examined actually existed
and were not merely accidental, and they suggest that the exami¬
nation of railway metals on these lines might be productive of
some good. — Dr. Rideal said that he had confirmed the presence
in commercial aluminium of calcium, and attributed it to bauxite.
—Before the papers were read the President announced the elec¬
tion of the following officers and Council : — ■
President. — Professor Dewar, M.A., F.R.S.
Vice-Presidents. — Professor Ramsay, Ph.D., F.R.S. ; Professor Emerson
Reynolds, F.R.S. ; Mr. Horace T. Brown, F.R.S.
Council.— Messrs. Haycock and Messel, and Dr. T. K. Rose.
Dr. F. D. Chattaway was elected an Auditor.
It was also announced that the Longstaff Medal had been
awarded to Professor William Ramsay for his late scientific achieve¬
ments.
The following papers were taken as read : — “ Dissociation Pres¬
sure of Alkyl Ammonium Hydrosulphides,” by J. Walker, D.Sc.,
and J. S. Lumsden, Ph.D. “Supposed Condensation of Benzol
with Ethyl Alcohol : a correction,” by F. R. Japp, LL.D., F.R.S.
“ The Viscosity of Mixtures of Miscible Liquids,” by T. E. Thorpe,
LL.D., F.R.S., J. W. Rodger.
Society of Arts. Wednesday, February 24. — There was a
large attendance at this meeting, the special attraction being the
reading of a paper on — -
The Production of Colour by Photographic Methods,
by Sir Henry Trueman Wood, Secretary of the Society, who, in
introducing the paper, stated that instead of dealing merely with
a single method he should endeavour to submit a brief resume of the
whole question of colour photography. He then described the present
method of dealing with the “negative,” showing the utter unsuita¬
bility of present processes for producing pictures in colour, or any¬
thing beyond pictures in light and shade. He also touched upon
the efforts made by numerous scientists to discover the process of
producing colours, from 1782 until the present time, and expressed
the opinion that the process which, at all events theoretically, most
nearly realises the idea of producing colours by the direct action
of light is that of Professor G. Lippmann, who first exhibited photo¬
graphs by his process in 1891. The idea was first thought out by
Lord Rayleigh, but Prof. Lippmann was the first to realise the idea in
practice. He placed a transparent sensitive film in immediate con¬
tact with a mirror, the mirror being composed of mercury. He found
that light of any colour falling on the film, passing through it and re¬
flected back along the same line by the mercury mirror, produced
in the film a series of strata, because there were points in the path
of each ray of light where the waves cancelled and re-inforced each
other. Where they cancelled one another there was no chemical
action ; where they re-inforced one another the chemical action
was increased. Thus he obtained, by the action of light, a
structure capable of showing, when illuminated by white light,
light of the same colour as had produced it. Experiments proved
the truth of his theories, and after some time M. Lippmann was
able to produce not only an image of the solar spectrum, but also
actual camera pictures from coloured objects, which, when
illuminated by white light, gave back the colours of Nature.
Unfortunately, they are by no means easy of production, nor are
they capable of reproduction, as ordinary photographs are. They
can be seen by the naked eye, but are only visible as coloured
pictures when viewed at a certain angle. Looked at directly, or
by transmitted light, they show no colour at all. The experiments
of Mr. Ives were next dealt with, his idea being that if several
pictures could be taken, each showing the proper tone and grada¬
tion of one of the primary colour sensations, and these pictures
could be combined into one, a picture with all the colours of Nature
would result. Chassagne’s and other interesting processes were
also described.
188
PHARMACEUTICAL JOURNAL.
[Feb 27. 18^7
THE WORLD Op PHARMACY.
- + — -
BUSINESS MEETINGS.
Chemists’ Assistants’ Association, Thursday, February 18:
Mr. C. Morley, President, in the chair. — There was an exception¬
ally large attendance to hear the following lecture on — •
THE THERAPEUTICS OF EMERGENCIES.
BY H. MACNAUGHTON- JONES, M.D., M.A.O.', M.CH., F.R.C.S.I. AND E.
The Ethics oe Counter Prescribing.
When you did me the honour of asking me to deliver a lecture
before your Association I hesitated before giving my assent for
two good reasons. In the first place I was doubtful of my being
able to spare the necessary time to prepare a lecture on any sub¬
ject which would repay this Association for listening to it, and, in
the second, I was doubtful of my ability to so handle the subject I
should select as to present it to you in a new, and at the same time
a practical, light. I knew that since I had first addressed you
various other well-known medical authorities had brought before
your consideration many topics of medical interest indirectly
touching on your professional calling. I have now, as I have had
all my life, a rooted objection to lecture for the mere sake of lec¬
turing, and I believe only in an ultimate result from any effort to
impart information which gives the listeners some practical, and,
may I say, some portable, form of knowledge ready to hand in
emergency without reference to any encyclopsedia or text-book.
There are certain facts connected with the everyday work of each
of us which require to be tabled in the tablet of memory without
any necessity of looking for them second-hand in a work of refer¬
ence. Though we cannot carry with us in our cerebral convolutions
an “ Enquire within upon everything,” we should have there for
ready consultation an “ Enquire within upon some things,” which
all of us must expect in the natural course of events
to be brought some time or other in contact with. If
I succeed to-night in fixing even a few useful and
practical facts on your memories, the knowledge of which
may possibly enable you in sudden emergency to relieve suffering,
to anticipate more serious consequences, or even to save an organ
or a life, I shall be amply repaid for any trouble this lecture may
have caused me. And here let me say, that it is no formally pre¬
pared effort on my part — I simply had no time for this. I was
working in Berlin when your invitation reached me, and I was then,
and have been since, employing all my spare time in fulfilling some
literary engagements I was bound to complete. You must, there¬
fore, extend to me your charitable consideration in listening to
these somewhat informal suggestions.
The Influence of the Pharmaceutical Training.
You have had, I understand, several lecturers of repute here who
have dealt with topics of pathological and therapeutical interest
bearing on different organs of the body, and your attention has
been occupied, not only with subjects of a general physiological
nature, but with such special organs as the eye, the ear, ancf the
larynx. And judging by the programmes of the subjects treated here,
which I have seen from time to time, one cannot fail to be struck
with the wide range of investigation and research which is included
in the syllabus of your discussions and yearly courses of lectures.
There is a fair inference to be drawn that pharmaceutical assis¬
tants, at least in this metropolis, form a body of highly intelligent
and capable men, whose general information on matters entirely
outside the region of the art they are trained, and profess to
practise, tends to give them broad and liberal views, not only with
regard to that art itself, but to all scientific and social questions
relating thereto. Nor can there be any greater testimony to your
careful training, the education you have received towards developing
exactness in your methods and experiments, and the caution with
which all your manipulative procedures are conducted, than the
fact that out of the millions of prescriptions daily dispensed
throughout the country, it is the rarest thing to have any mistake
in manipulation, any error of judgment in compounding, or mis¬
direction as to the use and application of the remedy. I say this
here, not in the least from any desire to please or flatter, but from
an honest appreciation on my own part of what I owe to the
pharmacist in the exactitude and care with which prescriptions,
demanding fine subdivision of dangerous remedies and their per¬
fect combination, are dispensed. Nor am I the less appreciative
from the fact that several years of my early life were spent in the
acquisition of that same method of compounding, the drudgery of
which apprenticeship I have never had any reason to regret. I
only refer to these traits which the calling of the pharmacist is
specially calculated to develop in order to urge that the very
qualities that are essential to make you good pharmacists
are also those which are most likely to find you ready in
the emergency of sudden accident or illness, calm and resource¬
ful in the face of unexpected difficulty, and which are at the
same time preventive of rash meddling and fussy interference.
Such lectures as you have had in your Association must, I take
it, have excited your interest and directed your attention more or
less to the causation of disease, and the relation which the physio¬
logical action and dosage of drugs bears to its cure. Indeed, you
would be unworthy of being regarded as intelligent, not to say
thoughtful, men if it were otherwise. Your special concern in
these subjects as pharmacists must surely centre round their
particular relationship to the application of that knowledge
imparted to you in your pharmaceutical capacity. Otherwise, I
should see but little advantage in the instruction which it is
possible to convey in a single lecture on such matters.
The Title of the Lecture.
Now, there are a few things I wish to say with regard to the
title of the subject matter of this lecture. It is all very well as
long as one glides along on good solid ice, keeping a safe and
reasonable distance from treacherous water. Only the foolhardy
run the risk of immersion by encroaching upon the thin crust of
the interdicted area. So it is with regard to certain vexed ques¬
tions — the wise and prudent avoid them. Still, it must frequently
happen, that advance in any direction, whether it be in science or
in art, in a calling or an exercise of athletic skill — witness our
Rugby football — is only to be acquired by an exhibition of that
very foolhardiness and rashness which the more cautious avoid
and condemn. And incidentally let me ask, for a moment
leaving thecbeaten track, is it not well occasionally to remember
and recognise the fact that “rashness,” even to the point of
foolhardiness, and sometimes beyond this, has been the quality
of all others to which the progress of the human race, of
civilisation, and of our own empire, owe the most? That is,
that rashness and daring, combined with audacity, which the
world generally counts as such, a rashness in which all considera¬
tions of self and self-interest are forgotten, and only the enthu¬
siasm — fatalism and fanaticism, if you will — of the devotee remains.
But such thoughts would entice us widely apart from the sub¬
ject we are considering. Indeed, touching on recent events, they
would carry us with the “Fram” to the North Pole, with a few
unarmed Englishmen to the Impi entrenchment of the Matabele,
and take us, not without some sad reflections, somewhere near the
sources of the Nile. While on the other hand, speaking of
medical occurrences, they would bear us back to such acts as that
of the Boston dentist, Horace Wells, which directly led to the
application of ansesthesia ; to the bold innovation of the Kentucky
surgeon, Benjamin MacDowell, which led up to our modern
abdominal surgery in women ; and, referring to more strictly
scientific and social gains, to Franklin and his kite, and Stephenson
and the “ Coo.”
Dangers of Counter Prescribing.
To return to my subject, let me at once state that, using the
term in its ordinary sense, I do not approve of pharmacists “pre¬
scribing.” It is incontrovertible that there must be elements of
danger, at times of considerable danger, attached to such
prescribing, no matter how simple such prescription may be. A
dose of Epsom salts, given in certain conditions, may indirectly
lead to the death of a patient, but then, on the other hand, the
same may be said of a mutton chop, as Sir Thomas Watson pointed
out. It all depends upon the circumstances in which the Epsom
salts or chop are given. To induce diarrhoea in a person sickening
for typhoid fever may have disastrous consequences, while to give
prematurely a mutton chop to the same patient in a condition of
convalescence may be equally dangerous. Nor can we get out of
the difficulty by assuming that the advised remedy is harmless.
The negative results of such action may be as hurtful as those
positive consequences I have just referred to. Delay in doing
the right thing is often as serious to the patient as indiscreet haste.
More deplorable still is that ignorance which prompts the
administration at the wrong time, or under contra-indicating
Feb. 27, 1897]
PHARMACEUTICAL JOURNAL.
180
circumstances, some unsuitable drug. And it must be always
borne in mind that some of the most fatal of acute diseases are
ushered in by the sudden appearance of symptoms which may not
in themselves appear to be serious, and which can be closely
simulated by those that are of every-day occurrence in the case of
transient affections of comparatively little moment. Even of still
greater importance is the fact that it is just in this class of affec¬
tions that a false step can never be retraced, and that any delay in
the application of the right remedy may be fatal.
Its Abuse and Consequences.
I see no excuse whatever, either as a matter of expediency or in
the light of philanthropy, for that class of prescribing which
affords a pretext to mean and penurious people of obtaining quasi¬
medical advice by buying a bottle of physic, or patent medicine,
over the counter. It is, as a rule, a shabby method of evading the
necessity of paying the doctor, and if successful defrauds a hard-
worked professional man of that which should by right find its way
into his pocket. Be it remembered, too, that the poor and impecu¬
nious are not the greatest sinners in this respect. The wealthy
stockbroker, and the wife of the rich city merchant, are common
offenders, and they are just the persons that the pharmacist finds
the greatest difficulty in refusing, though he knows that they are
trying to obtain an equivalent for proper medical advice on the
cheapest possible terms. Such seekers in search of information
generally come fresh, with addled brains, from the study of some
domestic work on medicine, or more orthodox medical encyclopedia.
Nothing is harder for the chemist’s assistant than to evade the
cross fire of “my lady’s” or “Mr. Midas’” questions as to what
is good for this or that condition, or under what circumstances
such and such a patent medicine may be taken. Nay, I confess
that it is well nigh impossible and contrary to all his interests to
expect him to do so. The question is a wide one, involves many
issues and interests, and has to be viewed from a broad and liberal
standpoint, for in it the public, as well as the pharmacist and
doctor, are interested. I maintain that the medical profession, in
its present struggle for existence amidst gross and unblushing
hospital abuses, cheap, so-called philanthropic enterprises, public
dispensaries, clubs, friendly and benevolent societies, and all the
other avenues by means of which ways are found to deprive the
struggling practitioner of his livelihood, is now more than ever
justified in regarding with a jealous eye any further inroads that
threaten to cripple its resources and imperil its ethical relations to
the public. At the same time, of this be sure, that the medical
profession as a body will never allow any selfish interests to stand
between its sense of what is right and the duty it owes to the
State and the public.
Duty and Privilege of the Pharmacist.
I hope that by this time you are not rehearsing to yourselves
the story of Balaam and Balak while listening to some of these
observations on the question of “ counter-prescribing.” But if
you should be mentally linking my personality with that of that
inoffensive animal who was the source of Balaam’s discomforture,
you will also kindly bear in mind a well-known fable which
indicates what results are likely to follow when that same animal
is alternately ridden, carried, or driven, to suit the interest,
bias, or prejudice of any individuals or class of the community.
I quite admit that it is well nigh impossible to draw the line
and say where the privilege and duty of the pharmacist cease,
beyond which his liberty of action must be curtailed. I admit
further that the whole tendency of modern thought, despite trades
unionism and caucases, is in the direction of individual freedom of
action. The liberty to do that which is right must ultimately
prevail, no matter how vigorous maj be the attempt, however
well-meaning, to curtail and imperil tne right of such independent
action, the motive springs of which are transparently pure and
right. What would be said of the man casually left in charge of the
Humane Society’s appliances, who hesitated to use them to save a
ife, because the authorised servant of the Society was absent ?
What should we say of the railway subordinate who, in the ac¬
cidental absence or sudden illness of the signalman, hesitated to
turn the points in view of an approaching collision ? And what
would be said of a pharmacist’s assistant who waited for the
coming of the doctor, in the face of a recent suicidal act of poison¬
ing, to administer the antidote which he had ready to hand?
It is, then, not a question whether any such right of action
serves, or is contrary to, this or that interest. It resolves itself
simply into the higher and wider issue of the best interests of the
State and the public, and the inherent right and duty of every
individual to serve these. To what end have we public lectures
on health, ambulance courses, popular works on health by dis¬
tinguished physicians, and popular journals on health and disease,
written for the railway bookstall ? Are not all these cheap methods
of educating the people how to doctor themselves without the aid
of either pharmacist or physician ? This they are, thanks to all
these means, always doing, and in daily increasing numbers,
since the competition in educating and training amateur doctors,
both male and female, has become so great.
Object of the Lecture.
So far as my remarks to-night are concerned, I wish it to bo clearly'
understood that I am referring only to those instances of absolute
emergency, where there is no immediate medical assistance at
hand, and where the delay necessary in procuring it may be
fraught with serious consequences to the sick or injured person.
I have deliberately chosen the title of ‘ ‘ The Therapeutics of
Emergencies ” in order to point out certain conditions under which
the pharmacist is justified in affording aid to a person who is taken
suddenly ill, or is accidentally injured. I am not dealing with the
giving of prescriptions for ordinary ailments. How far it will
ever be possible to prevent or restrain what is called “counter¬
prescribing ” it is not my place to inquire. I fear that the “pick-
me-up” of the early-morning-man-about-town, the “comforting
cordial” of the phlegmatic woman, the “liver tonic” of the irri¬
table dyspeptic, the dinner pill of the over-eating gourmand, the
worm powder for the puling child, the liniment for the “back¬
ache,” and a thousand and one patent combinations with their
widely advertised “miraculous” effects, will ever be had and
recommended for the asking. On the other hand, I maintain that
it is no part of the pharmacist’s work to usurp the prerogative of
the medical practitioner, and convert the chemist’s shop into a
consulting room or surgery.
Correlation of Medicine and Pharmacy.
And there is another strong point with regard to this question,
and that is the correlative trust and sympathy that should exist
between this great outpost of medicine and medicine itself. Phar¬
macy has ever been, and always must be, the active commissariat
in the advance of medical science. By and through your calling
we carry the attack into the enemy’s country. You furnish our
transports, you are always in our van, and ever adapting your¬
selves to the difficulties which beset our invading columns. There¬
fore, it is that each should look mutually to the other for loyal
support, and an inviolable offensive and defensive alliance. The
interests of both are best served by such a cordial understanding,
and anything that tends to weaken it, or to create distrust, jealousy
or angry feeling on either side, is greatly to be deprecated by both.
Let me now briefly, in the time at my disposal, cite as illustra¬
tions of these introductory comments some common contingencies
which will serve to exemplify their force and application. I select
some in which the pharmacist, in the unavoidable absence of the
doctor, may be called upon to give temporary assistance or advice
as regards the best thing to be done at the moment, or to be left
undone, pointing out in a few of these the danger that may attend
any meddlesome or injudicious interference, no matter how
apparently justifiable such action may appear to be.
It will be my endeavour to show that “masterly inactivity,”
pending well-directed and decisive medical action coming from the
responsible quarter, is often infinitely the safest course for the
chemist to pursue.
In the time at my disposal I shall have to be rather hurried in
the comments I make on some of these contingencies. As I had
not time to write these hints and suggestions, it is my intention to
put these together in a small booklet of three or four pages, and to
send a copy to each member of the Association, and then you will
have them ready to hand for reference.
Remarks on Various Emergencies.
Dr. Macnaughton- Jones then proceeded to discuss those
accidents to the eye which are of more common occurrence.
He pointed out that such wounds as stabs with sharp
instruments, or gunshot wounds, might, before being sent to
the doctor, have such a mydriatic as atropine instilled ; at
the same time he showed that in certain wounds the use of a
mydriatic is dangerous, and that therefore the best thing to do
in such cases is simply to occlude the eye with a little cotton¬
wool and light bandage, and send the case straight for medical
advice. To drop atropine into the uninjured eye, so as to
... 190
PHARMACEUTICAL JOURNAL.
[Feb. 27, 1897.
anticipate sympathetic trouble, was often useful. He entered
into the dangers of the indiscriminate use of heat and cold
applied to the eye, pointing out the serious consequences that may
arise from the application of either in certain cases. The value of
the magnet in removing steel particles resting on the cornea of the
eye was touched on, as also the best means of removing foreign
bodies from under the upper eyelid. All other cases of injury
should be sent immediately for medical advice. In the instance
of lime entering the eye, a weak solution of vinegar should be
used to thoroughly wash out the particles, and a little castor oil
and atropine subsequently dropped in, while an alkaline wash
should be employed immediately for any corrosive acids. Dr.
Macnaughton- Jones dwelt on the imprudence of any attempts to
remove foreign bodies from the ear, the only safe thing to do being
to syringe the ear, and that not too forcibly. No effort at extrac¬
tion should be made. The danger of poulticing an ear, or of
trifling with ear-ache, especially in the case of children, was
insisted upon. Warm fomentations, and the use of cocaine, were
allowable.
Foreign bodies in the nose should not be interfered with by the
pharmacist. The value of cold, through exciting reflex action, in
checking bleeding from the nose, was well known. Both matico
and hydrastis were useful, by plugging the nostrils with dossils of
cotton-wool saturated with the tincture and extract, in checking
the bleeding temporarily, but in old people, and those who are
“bleeders,” medical advice should be had at Once.
For burns and scalds, immediate exclusion of the air by wrapping
the part in cotton-wool was the principal thing to secure. Lint
saturated with lime-water and oil, and a little Friar’s balsam, is an
old and valuable application.
A scalp wound was best attended to by a doctor at once, but a
pharmacist might safely disinfect it and cut the hair.
The temporary adjustment of a wound in the throat was all that
can be achieved before a doctor arrives. The head should be well
depressed oh the chest, and kept in that position.
A matchbox is always at hand, wherewith to make a light
finger splint for a wounded finger, and a cork wrapped in lint
placed in the palm of the hand and the fingers bound firmly over
it will temporarily arrest bleeding from the palm.
The lecturer showed the advantage of flexion of the joints in
checking bleeding from these, and of the graduated compress
made with a small piece of cork and pads of lint gradually
increasing in size, for arresting bleeding from a blood-vessel.
Shock and collapse were what had to be feared from wounds of
the abdomen. Collapse must be treated by an injection of brandy
into the bowel, or a subcutaneous injection of ether.
A kick in the testicle, or other injury there, caused severe shock
and often bleeding. A capital suspensory bandage might be made
out of a pocket-handkerchief folded triangular-wise, and ice might
be applied to the injured part.
The care with which hot 'baths should be Recommended, espe¬
cially in the case of children, and the importance of the tempera¬
ture, was insisted upon.
If a person came complaining of bleeding from a tonsil, after its
removal, in the absence of the doctor a good mixture to sip was of
tannic acid, with gallic J acid, in the proportion of three parts of
the former to one of the latter (360 grains and 120 grains, in a few
ounces of water) ; half a teaspoonful to a teaspoonful of this to be
slowly sipped.
If a child should be brought with a scald in the glottis from
Sucking the pipe of a kettle, send immediately to a surgeon.
Tracheotomy may be required.
In the case of frost-bite, the important point to recollect was to
raise the temperature very slowly, hence the value of cold friction,
as with show and with alcohol. There should be no indiscreet
haste.
The lecturer then showed artificial limbs which had been rapidly
put up in splints extemporised from the sides of old millinery
boxes, and rolls of straw, wadding, and strips of old flannel. He
strongly advised every pharmaceutical assistant to take out a
Course of “ first aid ” lectures
The various methods of applying artificial respiration in the case
of drowning were referred to, and Sylvester’s method demonstrated.
The relative advantages of various caustics, preference being
given to nitric acid applied with a pointed stick into the cavity
made by the tooth, was entered into in dealing with bites of a
dog suspected to be mad. Many dogs were accused of hydro¬
phobia who were as sane as his hearers.
The mode of reducing a jaw dislocated from yawning was
humorously described. The application of a roller to the chest for
broken ribs, and the extreme care with which insensibility from
apoplexy, from alcoholic poisoning, or from opium must be distin¬
guished, were fully discussed.
In a case of suicidal hanging use artificial respiration until the
doctor arrives.
The ambiguous nature of such symptoms as costiveness, colicky
pains in the abdomen, and other apparently simple abdominal
troubles was forcibly impressed on his listeners by Dr. Mac¬
naughton- Jones, and the risk of mistaking such simple cases when
intestinal obstruction or strangulated hernia were present was not
to be forgotten. The lecture concluded with a reference to the
use of the stomach pump and syphon stomach tube, and the
poisons in which the use of both was justifiable or contra-indicated,
while those poisons in which time in the application of the anti¬
dote was everything were touched upon.
Exeter Dispensary, Saturday, February 20. — At the annual
meeting of the subscribers and friends of the Exeter Dispensary,
Mr. R. Y. Turner, the assistant dispenser, was appointed resident
dispenser and secretary in the place of the late Mr. R. Challice at
a salary of £200 per annum, and Mr. A. Sayer and Mr. Stone were
appointed as assistants at a salary of £85 per annum. — The full
Committee recommended that Mr. Sayer be the second dispenser,
and that he be expected in due course to qualify himself ; also that
Mr. Stone be third dispenser. The Committee further recom¬
mended that an allowance to Mrs. Challice, the widow of the late
resident dispenser and secretary, of £25 a year be granted, to be
voted annually by the General Court of Governors. —
The Rev. H. W. McGrath moved, and Mr. J. Carter
seconded the adoption of the report, but Mr. H. Michel-
more thought it was a serious matter to take £25 a year
out of the funds of the Institution when they were requiring extra
support, and he moved an amendment that no grant be made, this
being seconded by Mr. A. O. Sellefant. — Mr. H. Gadd, J.P.
(Vice-President of the Exeter Association of Chemists and
Druggists) said they wanted to regard Mr. Challice’s services with
the greatest feeling of kindness. Mr. Challice had received until
comparatively recently what he (Mr. Gadd) considered a small
salary. For the last- ten years Mr. Challice’s salary had, he
admitted, been fairly generous. If Mr. Challice had applied for
an increase a few years ago he Avould have had it, but he went on
without doing so, and, consequently, the Committee did not think
he needed one. Mrs. Challice was forty-eight years of age, and of
two daughters had one who was afflicted, and, he presumed, would
not be able to do anything to earn a livelihood. It might be said
that Mr. Challice ought out of his salary to have made provision
for his widow and family. Probably Mr. Challice ought to have
done so, but he was in a peculiar position for a benevolent-hearted
man, and he (Mr. Gadd) knew that (Mr. Challice
could not keep his hand out of his pocket when
distress came before him, and that was the sole reason
why he had not done anything for his widow and family.
He suggested that instead of an annuity, three years’ salary — £600
— should be placed in the hands of trustees to see that the money
was judiciously expended, and that Mrs. Challice had an oppor¬
tunity of securing a livelihood and caring for her children in a way
desired. He further suggested that by selling out the £9548
Consols and making equally safe and more profitable investments
the £600 could be secured. A long discussion followed, the
majority of the speakers being in favour of a grant,
whilst others did not think any funds should be made
out of this charity money. — Mr. Alderman Jones, J.P. , said Mr.
Challice had been a faithful servant for fifty years. He was injured
in the service of the Institution, and if he had applied the
Committee would have given him a pension. He (Mr. Jones)
could not think that now the subscribers would allow the widow
to go to the workhouse. The Committee had asked their legal
adviser whether the annuity could be legally voted, and under¬
stood that if approved by all the subscribers it could be paid. —
Mr. W. Wreford thought there was a great deal in favour of
making a payment in a lump sum. It would probably be more
beneficial and preferable to an annuity involving a discussion
every year. He considered, however, that £250 or £300 would be
a handsome sum to give. — Mr. Michelmore eventually withdrew his
amendment in favour of Mr. Gadd, who proposed that £300 be voted to
Mrs. Challice.— Mr. J. A. Loram seconded Mr. Gadd’s amendment.
Mr. Challice began in 1862 with £72 a year as an assistant dispenser ;
1865 his salary was raised to £120 with residence; in 1871 to £150 ; in
Feb. 27, 1897]
PHARMACEUTICAL JOURNAL.
191
1874 to £175 ; and in 1884 to £200 with residence since 1865. The
meeting must do an act of simple justice to the widow and
daughters. There was a time when Mrs. Challice would have been
in a better position, but owing to loss of money in the Liberator
and other societies she was now in straitened circumstances. —
In the course of further discussion, Dr. Woodman, as one of the
consulting staff of the Dispensary, said he hoped the meeting
would not let it go forth to the public that the Institution, after
having the life-blood of a man, as in the case of Mr. Challice, could
turn the widow into the streets or the workhouse. — Mr. Gadd’s
amendment was eventually carried by an overwhelming majority,
only four hands being held up against it, and the report as
amended was adopted.
Ulster Pharmaceutical Association, Thursday, Febru¬
ary 18, Mr. W. Prott in the chair. — A musical and literary meeting
of the members was held in the “ I.O.F.” Chambers, 5, Royal
Avenue, Belfast, when a large and representative gathering of both
pharmaceutical chemists and chemists and druggists of Belfast and
vicinity were present. The programme for the evening’s entertain¬
ment was of a very attractive nature. A sumptuous tea was served
at eight o’clock ; after which Mr. George Camlin read a most ex¬
cellent paper, entitled, “AChemist’s Life,” andan excellent musical
programme was then gone through, each item being enthusiasti¬
cally received.
Plymouth, Devonport, Stonehouse and District
Chemists’ Association, — Wednesday, February 17.— J. H
Bailey, Vice-President, in the chair. At a special general meeting,
held at the Foresters’ Hall, a motion was passed to rescind the recent
contract for parcels with Messrs. Curtis from London, owing to a
misunderstanding, and a fresh one made with The Globe to
members of the Association as follows : — 2s. per month for parcels
under 12 lbs. , one only from the same house daily, but the number
unlimited from different houses; above 12 lbs., 2s. 3 d. per cwt., not
deducting the former but including it in the cwt. The Special
Sub-Committee appointed to consider correspondence re C.A.M.
W.A.L. brought forward a resolution, which was adopted and
forwarded to the Secretary at Bristol. The Secretary of the Trade
Section, Mr. Condy U‘Ren, gave the result and list of replies, to a
circular sent out to members, re the New Trade Section recently
formed, which was considered very satisfactory, and the committee
were requested to proceed with the same, as a preliminary drawing
up a few rules, etc., to be confirmed at a general meeting
subsequently.
Liverpool Pharmaceutical Students’ Society, Thurs¬
day, February 18. — Mr. John Jones in the chair. — Among the
miscellaneous communications, which are always a strong point
Avith the “students,” Mr. Pierson mentioned that of late he had been
devoting some time to experimenting with menthol, in order to
arrive at the most presentable method of administering it in com¬
bination with other medicines in mixture form. His results were,
that if it be dissolved in spirit and then diluted with thin muci¬
lage, the menthol soon separates ; if dissolved in olive oil and then
emulsified with gum acacia a smooth mixture can be obtained,
and if rubbed up with powdered gum alone, and then the liquid
menstruum added by degrees, a good mixture is the result. — Mr.
Prosper II. Marsden said that, at the Liverpool Royal Infirmary,
in their menthol mixture consisting of —
Menthol . . . 5i.
Tinct. Card. Co . 3i.
Aq. Chlorof. . ad. Jxx.
The addition of S.V.R. §i. was necessary to get a clear mixture.
A root found in a sample of Spigelia root was shown by Mr.
Griffiths with a request that it should be identified, if possible, by
the members. According to Mr. P. H. Marsden, it was the
Carolina pink, Phlox Carolina, N.O. Polemoniaceae. A prescription
containing plumb, acet., pii. ; zinc, sulph., ,fss., to be divided into
twelve powders, had been dispensed by the President recently,
who found that a pasty mass was formed on rubbing the ingredients
together. When dried separately on a water-bath and then mixed,
the ingredients did not react and remained pulverulent. The
lecture on
Engravers and Engraving,
subsequently delivered by Dr. J. R. Logan, proved to be, as was
anticipated, of an extremely interesting nature. In mentioning
the various styles and branches of the art, the lecturer illustrated
his remarks by means of wood, steel, and copper plate examples
of the fine line, etching, mezzotint, and aquatint methods, all of
which illustrations were in the best of artistic style and taste.
Bradford and District Chemists’ Association, Tues¬
day, February 16.— Mr. Dunn in the chair.— Mr. W. Gardner,
Head Master of the Chemical Department of the Bradford Tech¬
nical School, lectured to the members of the above Association on
Modern Alchemy.
In opening his lecture he referred briefly to the early history of
alchemy, when it was associated with magic and physic. When
it became a separate science an experimental era was inaugurated,
and matter was believed to be one elemental principle, with four
partially interchangeable forms— earth, air, fire, and water.
Proceeding to review the efforts to discover a method of effecting
the transmutation of metals, which was one of the chief objects of
alchemy for centuries, he pointed out that there was a germ of
truth in the idea. Modern chemists believe that many metals
which are at present treated as elements are not elements at all,
and that in the future all known substances may be found to be
merely different manifestations of one element. At the same time
it is extremely unlikely that anything in the nature of trans¬
mutation of metals will ever be found practicable. In the
fifteenth and sixteenth centuries alchemy degenerated into mere
charlatanism and imposture.
Undoubtedly, observed the lecturer, the most sti’iking result
of modern chemical research has been the synthetical or artificial
production of natural products. In every direction the chemist, not
content with probing into Nature’s secrets by the mere analysis of her
products, has attempted to rival her in the actual economic produc¬
tion of many valuable articles which until lately were considered
to contain some vital organic principle, the result of some pecu¬
liar vital force, which it would always defy the art of man to
reproduce. Only quite recently it was thought that substances
which were the product of organic life, either animal or vegetable,
were essentially distinct in a chemical sense from the solids,
liquids, and gases which constituted inanimate nature. Thus
chemistry was divided into the organic and inorganic branches.
The synthetical production of such essentially organic products as
acetic acid, oxalic acid, and alcohol has, however, effectually
broken down this distinction, and now the terms organic and
inorganic were retained merely as terms of convenience. Many of
the most notable triumphs of synthetical chemistry, many of the
striking examples of modern alchemy, have been won in the field
of colour chemistry, which was closely related with the dyeing-
industry.
Before proceeding to deal with this branch, Mr. Gardner con¬
sidered briefly the various methods of producing and enriching
gas for illuminating purposes. The economical application of
heat in manufacturing processes has made great strides of late
years, and in the opposite direction, by the application of extreme
cold, Dewar and other workers have obtained marvellous results. It
is not possible to foresee the ultimate results of investigations
carried on at such extremely low temperatures as 200° C. below
zero, but it is probable that new light may be thrown on many
questions of great theoretical interest, such as the nature of
chemical affinity. It has already been established that under
these conditions almost all bodies emit a fluorescent light
after being excited, while even the most chemically active
substances appear incapable of entering into chemical union
with other bodies. Again, a considerable measure of success
has attended recent attempts to produce gems artificially.
The composition of gems is, of course, readily ascertained by
analysis, and a French chemist, Moissan, has succeeded by
the application of great heat and pressure in preparing artificial
rubies sufficiently large for jewelling watches, and diamonds which
can be employed for cutting and polishing natural gems, arming
the heads of drills, etc. It is, however, improbable that stones
of sufficient size to form valuable gems will be produced by the
present methods.
In perhaps no industry have the advances due to chemical
discoveries been more marked than in the art of dyeing.
The developments have been largely due to the production,
by artificial means, of a vast number of colouring matters
from coal tar, a few of them identical with dyes which exist
naturally in certain plants, but the greatest number being
absolutely new products. After showing a large number of
experiments to exhibit the manner of preparing various dyes,
192
PHARMACEUTICAL JOURNAL.
[Feb. 27, 1897
Mr. Gardner went on to say that many of the essences and
alkaloids which impart to natural products their peculiar flavour,
smell, or medicinal properties have also been made by laboratory
reactions. Tea and coffee owed their value as beverages largely
to the presenfce of an alkaloid known as theobromine or caffeine,
and within the last few months this has been for the first time
synthetically produced. Just as there are many artificial dyes
which have no prototypes amongst natural products, so there are
now several artificial substances which have been found of great
value medicinally. Among such are antipyrine, antifebrine,
etc. , and it is interesting to remember that medicine owes
these drugs to the colour industry, because they were first pro¬
duced in those monumental examples of the value of technical
education— the great colour works of Germany.
The physiological action of drugs is largely dependent upon
and governed by their chemical constitution, though physical
properties, such as solubility and volatility, were also very im¬
portant. As an example of the influence of chemical constitution,
the antiseptic and poisonous properties of certain aromatic deriva¬
tives was considered. Thus phenol (CgH5'OH) is both powerfully
antiseptic and an irritant poison, and resorcinol (C8H4(OH)2) more
active in both respects. On the other hand the three cresols
(CJL'CHvOH) while equally antiseptic are much less poisonous,
•meta-cresol B 4v xOH (3) ^av’nS the least lethal action. The
poisonous action is still further diminished by the intro¬
duction of a sitlpho group (S03H), while the antiseptic effect
is increased by substituting iodine for hydrogen in the molecule.
For this reason the di-iodo-cresol sulphonic acid is coming into
extensive use. In many manufacturing processes enormous
economies due to chemical research have been effected. The appli¬
cation of chemistry to hygiene and sanitation is daily bearing the
noble fruit of increased health and happiness to thousands, while
the value of chemistry to the agriculturist in connection with the
proper nutrition of crops has at last been settled on a secure basis.
In the midst of all these well- won triumphs, however, it must be
remembered that in many directions the boundaries of knowledge
lurve been advanced little since mediaeval times, and, as Lord Salis¬
bury has said, “We live in a small oasis of knowledge surrounded
by a vast unexplored desert of impenetrable mystery. ”
Proprietary Articles Trade Association (Hull), Thurs¬
day, February 18. — Mr. W. Stanning in the chair. — The chemists
of Hull and district met to cpnsider the aims and objects of the
Proprietary Articles Trade Association, and amongst those present
were Mr. Glyn-Jones, Mr. A. Sheffield, Mr. C. B. Bell (Hon. Sec.
and Treasurer), Mr. B. M. Stoakes, Mr. H. W. Hammond, Mr.
Thomas Marshall (Beverley), Mr. Charles Hobson (Beverley),
Mr. A. Markham, Mr. A. Crowther, Mr. James E. Dealing (Goole),
Mr. L. S. Selle, Mr. W. Attley, Mr. F. E. Lambert, Mr. Thomas
Henny, Mr. E. Howarth Earle, Mr. G. R. Foulston, Mr. W. H.
Walton, Mr. H. Schofield, Mr. J. Richardson, Mr. J. Oldham,
and others. Letters of regret for absence were read from Mr.
Ryley, Mr. Hoyles, and Mr. Saltmer.
"The Chairman said he was very pleased to see such a good
muster of chemists, not only of Hull, but also from a distance.
He thought their presence was a sign that the intolerant state of
affairs at present existing should be put an end to. Other towns
had expressed their opinions, and they thought it only right the che¬
mists in this wide district of Yorkshire should have an opportunity
of expressing their opinions on the question of the terms of sales
of proprietary articles. One thing he thought was rather a weak¬
ness, and that was the action taken up by some of the largest pro¬
prietary article manufacturers, such as Mr. Beecham, and also
Mr. Owbridge, of Hull.- — Mr. Glyn-Jones then proceeded to
explain the position of the Association, after which Mr. Richard¬
son moved : —
“ That this meeting of the chemists in Hull and district desires to express its
hearty approval of the object of the P.A.T.A., and pledges itself to support it
in every way possible."
He said they were pretty well all in the same box as regards this
matter, and he hoped all would avail themselves of the very valu¬
able machinery which was within their grasp to deal with it. It
was high time something was done to alter the state of affairs they
had been suffering from.
Mr. Earle seconded the motion. He referred to the wisdom of
pointing out the difference between the proprietors who had
placed their articles upon the list, and those who were thoroughly
in favour of the scheme. — Mr. Sheffield asked how the P.A.T.A.
proposed to deal with the wholesale houses which had not joined
the Association, and had no intention of doing so. — Mr. Richard¬
son desired to know how the co-operative stores would be affected. —
Mr. Foulston expressed himself in favour of having face prices.
He did not know whether, in supporting the P.A.T.A., they
would be supporting an Eldorado on a bubble. If it was an
Eldorado, what was it going to do for them ? He did not think
it was possible to coerce the proprietors. They should fight the
“ patent medicine men ” in every way. They were the enemies of
the chemists from beginning to finish. For showing goods, chemists
should insist on payment. ' It seemed to him that the present
methods of the P. A. T. A. would not benefit the drug trade.
Mr. Hobson argued that the Association was more likely to aid
the proprietors to obtain enhanced prices than to aid the chemists
in getting enhanced profits. — Mr. Hammond thought the effect of
the movement would be to make the cutting stores raise their
prices. That would open the eyes of the public.
Mr. Hearing thought the trade had not sufficient backbone.
The majority of chemists at Goole favoured this Association.
Mr. Walker said that since he adopted the practice of speaking
plainly to customers, he had not lost a single one, whilst he got a
little more profit on patent medicines. He thought the time would
soon come when they would get the face value.
Mr. Glyn-Jones dealt with the various points raised in the dis¬
cussion, and said he did not think they need have the least fear
that the proprietors would ever go to the stores, or that the stores
would support the proprietors unless they, like the chemists, were
able to make a profit.
The motion was carried with but one dissentient.
Mr. Stoakes proposed : —
“ That this meeting desires to convey to the various proprietors of proprietary
articles the advisability of their adding their articles to the ijrotective list,
and that the Secretary of the Hull Association be asked to convey this resolu¬
tion to the leading proprietors.”
He said chemists were all aware of the very powerful position
that the makers of these proprietaries held, and if they were able
to bring them upon the side of the Association a great deal of
work would be done. As it was they were all heartily sick of the
proprietary article trade as it had been conducted of late years.—
Mr. Sheffield seconded the motion, which was carried unani¬
mously. ... . .. _
Mr. Lambert moved —
“ That the Hull Chemists’ Association be requested to ask that it be the local
executive for the P.A.T.A. in the Hull district.”
Mr. Walton seconded the motion, and it was also passed without
opposition.
Proprietary Articles Trade Association. — Election of
Council, March, 1897- — The following is a list of candidates for the
retail section : —
Barnes, W. R., Upton Manor, London.
Cocks, J., 8, Edgscumbe Street, Stonehouse, Devon.
Cooper, A., 80, Gloucester Road, South Kensington, London.
Davies, J. T., 13, Walter Road, Swansea.
Garrett, T. P., 33, Commercial Street, Newport.
Groves, R. H. , Market Place, Blandford.
Hessell, J., 143, Highgate Road, London.
Jones, W., 2, High Street, Birmingham.
Pickard, S. N., 74, Manningham Lane, Bradford.
Rowsell, F., 74, High Street, Exeter.
Seely, H. W., 14, Southgate, Halifax.
Spyer, N., 13, Gledhow Terrace, South Kensington, London.
Warren, F. W., 340, Harrow Road, London.
Williams, J., Broadfield, Davenport, Manchester.
Wokes, T. 8., Grassendale, Liverpool.
Voting papers will be issued to members on or about March 2, and
the election will take place the week following.
Feb. 27, 1897]
PHARMACEUTICAL JOURNAL.
193
SOCIAL MEETINGS.
Brighton Junior Association of Pharmacy, Wednes¬
day, January 17. — Mr. Williamson in the chair. — This was a
musical and social evening. The programme was carried out
under the direction of Messrs. T. Little and Beckwith, and was
admirably sustained by Messrs. A. J. Davies, Day, W. Lauder,
Colway, J. King, 0. Hebb, Little, and Beckwith.
Nottingham and Notts. Chemists’ Association, Tues¬
day, February 23. — The annual dinner of the Nottingham and
Notts. Chemists’ Association was held at the Albert Hotel, Derby
Road, Nottingham, Mr. R. FitzHugh, President of the Associa¬
tion, occupying the chair, and Mr. A. Middleton (Vice-President)
and Mr. J. Wilford (Hon. Treasurer) the vice-chairs. It was a
very successful and pleasant little function, among those also
present being Messrs. A. Eberlin (Hon. Sec.), A. C. Vallance, J.
R. Spencer, Parkhouse, Gill, Hare, Jackson, W. Widdowson, A.
Beilby, S. Cook, J. Radford, R. Beverley, E. Gascoyne, Brown,
Allum, Clark, F. R. Sargeant, W. H. Smith, E. E. Turton, J
Davis, Freeman, Roberts, Shacklock, Dudley, Smith, Ball, R
Widdowson, J. P. Bailey, S. Parr, Wilford, Junr., etc. The
loyal toasts were given from the chair, and enthusiastically
honoured. — Mr. F. R. Sargeant proposed the toast of
The Pharmaceutical Society of Great Britain.
He said he felt it to be a great honour to propose the
toast. If he had been asked to submit the toast ten years
ago, he should have said something after this style: “You had
better get somebody else,” and would have simply thrown
mud in the face of the Pharmacentical Society. But some
people had to be touched through their pockets, and it was in that
way that he was first led to see the usefulness and value of the
Pharmaceutial Society. Ten years ago a proposal was made
that their Association should establish a dispensing class, and he
thought something like three years elapsed before anything
came of it. They were short of funds, or for some reason or
other the finance Committee did not feel disposed to launch
the scheme, but the Pharmaceutical Society gave them a
handsome grant of twenty-five guineas. That led him to
believe that the Pharmaceutical Society did take an interest
in junior and kindred societies, and gave them some help in order
to make them flourish. When they came to look at what the
Society was founded for, he did not think it had fallen short of its
ideal. The Society was founded in 1841 for the purpose of ad¬
vancing chemistry and pharmacy, promoting a uniform system of
education amongst those who carried on the business of chemist
and druggist, and lastly to provide a fund for the relief of dis¬
tressed members and associates of the Society and for their widows
and orphans. With regard to the Society in Edinburgh, no one
would say a word against the Society in that particular. The
Society had gone as far as it possibly could in that direction.
They had now examinations which kept out of their ranks
men who, by their lack of education, were unfit to become
chemists. And then it had shown its interest in other societies,
while the Benevolent Fund was in a fairly flourishing
condition, and it did a great deal of good to those who needed its
benefits. In the matter of protection the Pharmaceutical Society
had done as much as it could for them. If it had not done more
it was the fault of chemists, because they had not supported
it more loyally. The Society prosecuted grocers and others who
would sell poisons, and in that direction it had done as much as it
possibly could. The great point was this — that as a body, they
did not support the Pharmaceutical Society as they ought to do. He
believed there were fifty-five or sixty chemists in business there, and
he thought he was right in saying that only twenty-five supported
the Pharmaceutical Society. What could a society do in legal and
parliamentary matters when it had not greater support behind it
than that. If it could say it had the general body of chemists
behind it, then he was perfectly sure it could do more than it did.
He thought the Pharmaceutical Society was the best body they could
support in England. This was the diamond jubilee of the Queen,
and he should like every chemist in Nottingham to become sub¬
scribers to the Society, and also that every chemist who subscribes
to the
Benevolent Fund
should double his subscription. One suggestion he would
like to make to the Pharmaceutical Society, and that was
that when a young man went up for his examination in six
subjects, supposing he passed four of them he was a ploughed
man, whereas in the medical profession the student could go
up for the others. He thought that was very hard. He
begged to couple with the toast the name of a gentleman who was
far more burning in his enthusiasm for the Pharmaceutical Society
than he was. He referred to Mr. Bolton, the local secretary.
Mr. Bolton, in replying, said his task had been made very easy that
night because of the speech of his friend, Mr. Sargeant. On behalf
of the Pharmaceutical Society, as its local representative, he thanked
Mr. Sargeant for his eloquent speech on behalf of the Society. Mr.
Sargeant had spoken of the education of the Society. The only mis¬
take of that Society lay in the fact that it was something like thirty
years before its time. It laid down in 1852 this fact : that every
young man entering in their business should receive a proper tech¬
nical instruction to fit him for their trade. They now saw that the
demand the Society then made was quite right. That was neither
the time nor the place to go through the leading facts in the history
of the Society to prove that it was worthy of their support. There
was just one thing he would like to refer to, however. One of the
leading features of the Society was that it had stood up for the
protection of the interests of the chemists and druggists in the
country ; it had never been behind in that matter, and such had
been the justice and fair dealing for which it had stood up, that
it had always had at its back some of the most respected
men in the House of Parliament. It was acknowledged on ■ all
sides that last year was a very barren year as to political benefits
to the community, but during that year there were four Bills
brought forward of the very greatest importance to chemists
and druggists. He wished to point them out so that those who
asked :
“What is the Good of the Society?”
might see that the Society had been a very useful organisa¬
tion to the trade, and had prevented laws from being
placed on the Statute Book that would have been very
derogatory to them as a body. Of the four, the first and
foremost was the law relating to the adulteration of drugs,
the second referred to weights and measures, the third was
in reference to the sale and storage of petroleum, and
the last and most important of all was the registration
of limited liability companies. In all these questions the Society
came to the front in the interests of their trade. The Pharmacy
Act was made abortive in consequence of the decision in the
Higher Court that a company could do what a single individual
could not. They all knew that a Bill came before the House, and
that the Pharmaceutical Society obtained the assistance of the
British Medical Council and the Veterinary College of Surgeons
with the object of getting added to that Bill a clause which was of
the greatest importance, the clause being to protect their personal
professional titles from abuse by irresponsible and impersonal
limited liability companies. That clause was backed by no other
than Lord Herschell himself. It passed the second reading, and
was sent to a Select Committee. Some of their friends began to
say it would never become the law of the country, but
what did they find? Already in the present Parliament
the Bill had been read a second time, and had been referred to
the same Seleco Committee, so that it stood exactly where it did
in the last Session. If they only supported the Society by becom¬
ing members and subscribing liberally, and giving it their moral
support, then it would be able to take up such harmful questions
as he had referred to, and with strengthened power, be able to
prevent them getting on to the Statute Book. There was one
little point he would like to refer to. Those of them who saw the
Pharmaceutical Journal
would probably have noticed an admirable editoral article
on army dispensers. A school had been formed by the Army
Service Corps, wherein men could pass an examination of the
most simple kind, and in the most rudimentary manner, after the
least possible training. Andnotonly was Tommy Atkins going to be a
dispenser to his brother soldiers after the smallest instruction, but a
claim was being made to the Local Government Board on his behalf
that he might be admitted as dispenser to Boards of Guardians.
They could all see what a serious thing it would be to flood the
country with men totally unfitted to fulfil those duties. If chemists
did not support their Society, the result was that it was not able
to do the work which they expected of it, and in future years there
would be a deal of complaining that so little in this directi -n had
been accomplished. With regard to the Benevolent Fund, last
year the Society paid £2795 in grants and annuities. This year
was the diamond jubilee of Her Majesty, and they were anxious
that something should be done on the lines foreshadowed by Mr.
194
PHARMACEUTICAL JOURNAL.
[Feb. 27, 1897
Sargeant. He was glad to hear that gentleman was so enthusiastic,
because he (Mr. Bolton) had received that day from the central
authority in London a few very important sheets of paper which set
forth the advantages of that Fund. He had no doubt that Fund
would always receive the utmost sympathy from chemists in
Nottingham. This year he hoped they would be able to do more
than they had done in the past to support a fund about whose use¬
fulness, value, and needs there was no question, because every
pound given to it went to the object for which it was devoted.
Nothing was used for clerical or printing expenses or for salaries,
so that he hoped they would remember that charity began at home.
He thanked them very much for the way in which they had re¬
ceived the toast.
Mr. A. C. Yallance proposed “ The Nottingham and Notts.
Chemists’ Association,” which he described as a pattern associa¬
tion for the way in which it looked after the interests of chemists
and pharmacists. He thought, however, that the Association did
not pay sufficient attention to the social side of their calling.
The President first replied to the toast. He said he had been
President of the Association for the last fifteen or sixteen years,
and he hoped the chemists of the town would make the Association
a greater success than it had been in the past, and he for one
would be most happy to help carry out any suggestion that would
tend to bring that desired end about.
Mr. J. Wilford, Treasurer, remarked that the Association was in
a flourishing state financially, the classes kept up in numbers, and
the young men got a splendid education at University College.
Mr. A. Eberlin, the Hon. Secretary, also acknowledged the
toast. He said he took it that the primary function of their Asso¬
ciation was education. He could assure them that this year they
had exceeded anything they had done before. The Association
was in a most flourishing condition as regarded its educational
matters. The classes had been well attended ; the numbers
exceeded those of any previous year, and the reports he had
received from the College authorities were of the most encouraging
nature. Somebody had referred to their Association as the pattern
Association, and he thought as regarded educational matters it
was undoubtedly the pattern Association. He thought no provincial
town had an association in which there were educational advantages
such as they possessed in Nottingham. Frequently he received
requests from kindred associations for details as to their manner
of working, and it seemed to him that theirs was looked upon
as the most flourishing Association in the provinces on educa¬
tional matters. He wished he could say the same as regarded
their apprentices generally. He did not wish to harp in a
pessimistic tone, but he should like to see a greater number of
them members of the Chemists’ Association. He would suggest
that the best way of promoting his health, would be to reply to
the notice they received from him as soon as they could. That
would be far better than drinking his health, and it would not
only promote it, but prolong his life.
Other toasts followed.
LEGAL INTELLIGENCE.
PROCEEDINGS UNDER THE PHARMACY ACT.
Prosecution at Airdrie.
At the Sheriff Court House, Airdrie, on Friday, 19th inst.,
the cases of Bremridge v. David Lees, and John E. Miller came
before Sheriff Mair at a pleading diet in Chambers.
Mr. Robert Watt, solicitor, Airdrie, instructed by Mr. P.
Morison, S.S.C. Edinburgh, prosecuted, and Mr. Brock, of
Messrs. Brock and Ballantyne, solicitors, Glasgow, appeared for
the defence.
Defendant David Lees was charged with selling, in the shop of
Dr. Arthur, 1, High Street, Airdrie, laudanum on two occasions
and Powell’s balsam on a third occasion to an agent of the
Registrar.
Defendant appeared, and on his behalf Mr. Brock made a
lengthy statement, objecting to the relevancy of the complaint on
several grounds, which were repelled by the Sheriff ; a question as
to the quantity of opium sold being reserved to be dealt with if
necessary on the merits.
Defendant then pleaded not guilty, and the case was adjourned
to Monday, March 1, for trial.
On the case against JohnE. Miller being called, a medical certifi¬
cate was produced, certifying that he was|too ill to attend, and the
case was adjourned till May 7. He was charged with selling a
belladonna plaster in the shop of Dr. Arthur, 1, High Street,
Airdrie, to an agent of the Registrar.
PROCEEDINGS UNDER THE FOOD AND DRUGS ACT.
The Sale of Adulterated Glycerin.
At the Birmingham Police Court, on the 19th inst., Frank Clent,
of No. 1, Cooksey Road, was summoned for selling glycerin not of
the substance and quality demanded. The prosecution was con¬
ducted by Mr. Hiley (assistant Town Clerk), on behalf of the Health
Department, and Mr. Philip Baker, solicitor, defended.
Mr. Hiley informed the Bench that, so far as he was aware, that
was the first prosecution in Birmingham with reference to adul¬
terated glycerin, and there were two summonses issued against
two persons Avho were wholesale druggists, charging them with
selling glycerin largely adulterated with dilute glucose syrup.
About the end of January the inspector under the Food and Drugs
Act found a considerable number of penny bottles of glycerin being
sold in small shops, and inquiries revealed the fact that the article
was in many instances supplied by the defendant. On February 4
a dozen bottles were purchased at defendant’s shop, and on the
article being analysed it was found to contain a large percentage
of syrupy sugar, which, instead of possessing healing properties,
had no medicinal value whatever. Each of the bottles was labelled
“Pure Glycerin.” After the summons was issued defendant
called at the Health Department, and admitted he knew the
glycerin was adulterated, and asked that the proceedings might
be stopped.
Annie Bennett spoke to purchasing a dozen bottles of glycerin
from defendant, for which she paid Id.
Inspector Jones and Chief Inspector Parker deposed to conversa¬
tions they had with defendant. Parker said that defendant told
him he knew the glycerin was adulterated. Others were doing it,
he said, and he was forced to do so.
Dr. Hill, the city analyst, said that the sample he received from
Jones proved, on analysis, to contain 45 per cent, of dilute glucose
syrup, or syrup of stai'ch as it was called. Glycerin should con¬
sist of a sugar extracted from fats and oil mostly by steam, or in
soap making as a by-product. It was a pure syrup, and was a drug
endowed with active medicinal properties. It was used as a
medicine itself, and as a vehicle for other medicines. Nearly one
half of the sample he analysed consisted of the starch he had men¬
tioned, which was a sugar artificially manufactured by chemical
means from common starch. It possessed no medicinal proper¬
ties, and was not a drug in any way. Glycerin in its general form
was not explosive. That described by him in his analysis would
not be injurious. It would only have half its proper value.
Mr. Baker : Concerning the- value, is it a fact that it would be
very difficult to sell a bottle of pure glycerin at a penny ?
Dr. Hill : Glycerin is cheap enough, about 8 d. a pound. It is
not a question of cost with me, it is a question of purity.
Mr. Baker asked the magistrates to deal leniently with defen¬
dant, who, since the proceedings were taken against him, had had
the misfortune to have his shop and uninsured stock destroyed by
fire.
Mr. Ryland (Chairman of the Bench) said that although that
might be the first case brought forward, they could not look upon
it as the first case of adulteration. Even people possessed of no
chemical knowledge must know they must not supply articles
adulterated like the one in question. A penalty of £5 and costs
was imposed.
The defendants in the second case were George Turley and
Edward Law, trading as Turley and Co., wholesale druggists, 59,
Edgbaston Street. The charge in this case was that of selling
glycerin containing 40 per cent, of glucose syrup, and the
defendant Turley, who appeared, pleaded guilty.
The purchase of a dozen bottles on January 28 was proved, and
Dr. Hill certified that the glycerin contained 40 per cent, of
glucose syrup.
Defendant asked permission to make a statement, and said that
during the last twelve months the price of glycerin had gone
nearly from £40 to £80 per ton. People who had been in the
habit of getting a certain size bottle for one penny for years-
demanded a similar one now. When the price increased they
sent out half-sized bottles, but the people would not have them,
and their travellers said that as other people were "selling the
adulterated article they would have to do so if they were to
Feb. 27, 1897]
PHARMACEUTICAL JOURNAL.
195
keep their trade together. The article in question was never
bought for medicinal purposes, but only for rubbing on the hands.
Glucose was one of the most harmless preparations in the world.
Mr. Ryland said that what defendant said showed that the
glycerin was adulterated to make it saleable at the price.
Mr. Carter (Justice’s Clerk) remarked that it was extraordinarily
difficult to make some people understand the Food and Drugs Act.
In that case the defendant was giving himself away.
Defendant : These bottles should have been labelled * ‘ Glycerin
Compound,” and then it would have prevented me being here. I
have been in the trade twenty-five yeai’s, and I have never been
summoned before, and samples have been taken from my place
many times. Under the circumstances, I ask you to deal as
leniently with me as you can.
Mr. Ryland : This may be the first time you have been found
out, but it is not the first time of adulteration. Therefore you
will have to pay £5 and costs. I think you will do well to get a
copy of the Food and Drugs Act and read it through.
HIGH COURT OF JUSTICE.
Hunyadi Janos and Uj Hunyadi Waters.
On the hearing of the action of Saxlehner v. the Apollinaris Co.
being resumed on Thursday last, the following gentlemen were
called as witnesses, Mr. Charles Joseph Rees, of Gray’s Inn Road ;
Mr. Thomas Hudson, of Liverpool ; Mr. Thomas F. Abraham
(Clay and Abraham), Mr. James Thomson, Mr. Robert Buchanan,
managing-partner of the Glasgow Apothecaries Co. ; Mr. Adam
Gibson, wholesale chemist, Edinburgh ; Mr. Augustus W. Orr,
Dublin ; Mr. Thompson, of Thacker and Hobbs ; and Mr.
Samuel Parker Boyd, of Boyd and Boyd. The effect of
these gentlemen’s evidence was that “Apenta” might be
passed off and accepted as Hunyadi J anos water previously sold
jjy the Apollinaris Co. Mr. H. D. Skinner then deposed to having
visited thirteen different towns in the United Kingdom, where
he had obtained from chemists bottles of “Apenta” in response
to his request for “Hunyadi Janos” water.
Sir Frank Lockwood, in opening the case for the defendants,
sketched at considerable length their relationships with the late
Mr. Saxlehner, after first correcting a mistaken impression of Mr.
Richter, the plaintiff’s manager, that the cost of defendants’
springs in Buda-Pesth was 100,000 florins, it being 400,000 florins,
the purchase being made in the open market and with the full
knowledge of Mr. Saxlehner. He indignantly repudiated the
suggestion that there had been a deeply-laid plot, dating back to
1876, to take the contract from Mr. Saxlehner and to convert it to
defendants’ personal ends. The hardship of this suggestion was
the more keenly felt by the defendants, seeing that they spent
not less than £39,000 in advertising the plaintiff’s water, and
thereby converting an absolutely insignificant trade into one of
world- wide renown. Not a tittle of evidence had been given to
show that after defendants ceased to take plaintiff’s water her
previous profits were diverted to them. There was, in 1885, a
dispute, followed by proceedings, between the defendant company
and Saxlehner as to the quality of the water, and in 1887 a judg¬
ment was given in respect of a Hunyadi water called Arpas. Until
the alteration of the law in Hungary in 1895-6 there were any
number of springs used and waters sold there under as many
names with the prefix Hunyadi, and time after time Saxlehner
tried but failed to get them off the register, until the amended law
placed him in possession ; and but for the defendant com¬
pany’s action there could be no doubt a similar result would have
followed here, and plaintiff would have been unable to say that for
twenty years he held a monopoly in the water in this country.
As to the defendants’ registration of the trade mark, when it was
discussed between them and Saxlehner, whilst they insisted
on their right and at first refused to transfer it to his name,
eventually they consented to that course. And to show their bond
fides, when efforts were in 1888 about to be made in New York to
dissolve injunctions granted against some of these “Hunyadi”
waters, defendants asked Saxlehner to join in or bear the expense
of contesting the cases in support of their mutual interests, but he
declined. The dissolution of these injunctions being allowed to
pass unopposed, operated in defendant’s mind in introducing their
diamond mark.
Mr. J ustice Kekewich here intimated that the learned counsel
need not further deal with that part of the case, as he was satisfied
there was no substantial ground for complaining of the use of that
mark.
Sir F. Lockwood said this mark had been used by defendants
from 1887, with regard to five waters, and from 1890 on four others ;
the total sales being 355,000 bottles, demonstrating the ground¬
lessness of the charge that the defendants’ was a fraudulent con¬
spiracy. As further proof of the real feeling of the defendants, he
pointed to the fact that when in 1891 ’ Mr. Justice Romer gave a
decision with reference to Hungarian Aperient Waters, they
withdrew all the show cards they had issued bearing those words,
circularised their customers, and from that time had not used the
phrase in their advertisements ; they also put on their Diamond
Star label, a note that it was simply to indicate that the water so
sold was imported by the Apollinaris Company ; and for taking pro¬
ceedings at Saxlehner’s request, against persons using
the word “Hunyadi” the Hungarian Courts actually
fined them as “stiff-necked litigants.” He should prove
that the springs from which' ' defendants draw their
water were in tbe same district, and possessed all the quali¬
ties of the plaintiff’s, and some which were superior, The whole
operations of the defendant company were open and above board,
and when the Hungarian Courts, On an ex parte application,
expunged their names from the register in that country, after a
short time for consideration, they offered to withdraw the use of
the word here, and by that offer they 'still loyally stood. The
“ Apenta ” label was expressly designed to prevent mistakes, and
he submitted that, being absolutely distinct from the plaintiff’s,
the defendants were entitled to use it?* ‘
Mr. Julius Prince, the former seotetary, and now a director of
the defendant company, was then called, and after giving certain
evidence, the further hearing was adjourned to Tuesday.
When the case was resumed on Tuesday last, the court was filled
with chemists and druggists, some fifty of whom, it was rumoured,
had been subpoenaed to speak to other Hungarian waters having
for some years been sold in this country as “ Hunyadi,” and that
the get-up of the defendants was, of such a character as plainly
to distinguish it from that of the plaintiff.
Mr. Julius Prince, the defendants’ managing director, having
given evidence as to the circumstances under which they acted,
and the efforts they made by the issue of 30,000 circulars to
explain their position, and the adoption of the word “Hunyadi”
as one common to the trade and used on a number of Hungarian
waters sold in the United Kingdom,
Sir Frank Lockwood called what he afterwards described as
wholesale and retail samples of a mass of evidence as to the sale of
Hungarian waters as “ Hunyadi” and the adoption and probable
effect of the defendants’ diamond trade-mark.
The gentlemen called included Mr.: T. H. W. Idris, who said
among other things that he had heard of customers who bought
“Hunyadi” ab a lower price than his firm charged, but on
investigation they found it was nob “Hunyadi Janos,” which was
the only kind his firm sold.
Mr. Thomas Best, of Henrietta Street, Cavendish Square, Mr.
Sloper (Randall, Sloper, and Co.), of Southampton, and Mr. Alex¬
ander Bottle, Dover. The latter gentleman said that if a customer
applied for “ Hungarian bitter water ” he should supply “ Hun¬
yadi J&nos,” because that was the original water.
Dr. James Welsh, of Dublin; Mr. W. Page, of Ramsgate; Mr.
Andrew Morrison, of Glasgow; and Mn John Ray, manager to
Taylor’s Drug Company, of High Holborn, who had had twenty
years’ experience in the mineral water trade, were also called, and
Sir Frank Lockwood, in summing up the defendants’ case, said
that as owners of springs in the same district as Saxlehner’s, finding
the competition in what they regarded as a word common to the
trade, they in self-defence adopted it, as identifying their water,
and in the belief that they were entitled to use it in connection
with what had become recognised as their diamond trade mark.
He did not hesitate to attribute to Saxlehner’s influence over the
authorities in Hungary their decision ex parte to grant him the
exclusive use of the word in that district, but when the dafendant3
heard of this they altered their label, which was now so distinctive
from the plaintiff’s as justified his submission that it was not
calculated to mislead.
Mr. Justice Kekewich intimated that he should grant a limited
injunction restraining the use of the word “ Hunyadi,” but invited
Sir Frank to address himself to the question of an inquiry as to
damages.
Sir Frank Lockwood submitted that no damages having been
either pleaded or proved, his lordship would nob enlarge the relief
asked for. 0 . 1
Mr. Warrington having been heard on the same side,
196
PJTARMACEUT I CAL JOURNAL.
[Feb. 27, 1897
Mr. Warmington, in reply, on his lordship suggesting that he
proposed to deal somewhat severely with the matter of costs, sub¬
mitted that the plaintiff was driven to this litigation in order to
protect her own interests. He had not concluded his address
when the Court rose for the day.
On Wednesday Mr. Warmington continued his argument in
reply, with a view to showing that the plaintiff was entitled to
the full costs of the action, and cited several decisions of the
House of Lords to show that he was justified in the course he had
pursued in opening the case, and in the evidence he bad adduced.
He also urged that the plaintiff was entitled to an account of
profits, for which he cited Lever v. Goodwin, the sunlight soap
case.
Mr. Warrington having made some comments on the cases cited
in reply by Mr. Warmington, his lordship reserved judgment.
CORONER’S INQUEST.
The Unrestricted Sale of Chlorodyne.
The Manchester City Coroner held a lengthy inquiry on Feb¬
ruary 23, touching the death of Annie Salter, sixteen years of age,
small ware weaver of Maple Street, Hulrne, Manchester. On
February 20 the girl purchased three pennyworth of chlorodyne,
saying she wanted it for a cough. On the following Monday she
was found lying in bed, unconscious, and died at the Royal
Infirmary from chlorodyne poisoning. An open verdict was
returned, and the Coroner, commenting upon the purchase of the
poison by the deceased, said if the sale of chlorodyne had been
stopped long ago many lives would have been saved. If it was to
be used at all, it ought to be sold with the utmost caution, and
never to children. It had been the opinion of coroners for years
that the free sale of chlorodyne ought to be stopped.
NEW REMEDIES.
[ Inventors and manufacturers are invited to submit specimens of
novelties, descriptive notices of which will be inserted for the informa¬
tion of readers of the Journal. Whenever possible, illustrative blocks
adapted to the width of the Journal columns should accompany the
particulars sent. Address : Editorial Department, 17, Bloomsbury
Square, W.C.\
Chelidonine Salts as Anodynes. — Chelidonine phosphate and
chelodine sulphate are colourless crystalline salts easily soluble in
water ; the tannate is a whitish yellow powder almost insoluble in
water, soluble in spirits of wine. It contains 53 -5 per cent, of
pure alkaloid. These chelidonine salts are recommended for alvine
pain, and as a sedative in ulceration of the stomach in place of
opiates. The dose is from 10 to 20 centigrammes. — Ph. Zeit.,
xlii., 107.
Fumitory in Skin Diseases. — The aqueous extract of Fumaria
parvijlora is recommended in doses of 0 '5 to 2‘0 Gm. as a specific
for leprosy, cancer, eczema, and similar diseases. It acts as
a laxative and as diuretic. — Ph. Zeit., xlii., 107.
Monol ; Calcium -Permanganate. — Bordas suggests “monol”
as a synonym for calcium permanganate, which he finds to be an
antiseptic and germicide more powerful than the corresponding
potassium salt. We cannot regard the synonym as necessary ; the
chemical name of the salt is not indefinite as monol is, nor
unwieldy as are those of some synthetic bodies where an abbreviated
and terse name is a necessity for lay use.
Bismuth Tribromophenol as an Antiseptic. — Cumston states
that of all the groups of antiseptics, bismuthum tribrompheny-
licum, or, as it is also termed, “xeroform,” is recognised as the
most active, first, because it contains, besides 49 per cent, of
oxide of bismuth, 50 per cent, of triobromophenol, while other
products only contain from 10 to 20 per cent, phenol cresol, or
naphthol ; and, secondly, tribromophenol is more antiseptic than
phenol. It is a fine yellow neutral powder, which does not decom¬
pose when exposed to light ; its odour is slightly carbolic, it is
tasteless, and does not irritate the mucous membrane of the diges¬
tive tract. The author strongly recommends this substance to the
profession as a safe and sure antiseptic, and in many respects
superior to iodoform or other powders of tbis class. — Bos. Med. and
Sur.Jour., cxxxvi., 37. ...
NEW IDEAS.
Vinolia Sachet
Sffi/anckau, (^r
LONDRES KCW-YORK
PERFUMES AND TOILET ARTICLES.
Messrs. Blondeau et Cie, of Malden Crescent, evidently
intend to keep pace with the times, and are constantly adding-
novelties to their list. During the comparatively few years this
firm has been established they have come to the front, and mean
to' stay there if one may judge by the care, ingenuity, and taste
devoted to their productions. One of their latest methods for
publicity is to present free to buyers of one gross of perfumes a
specially designed display
counter card holding three
dozen tiny samples of the
different odours, which can
be retailed at 3d. or given
away to customers when
thought advisable. Vinolia
Sachets, comprising six¬
teen different kinds, each
in an elegant envelope,
printed in subdued tints,
and bearing a small artistic
vignette, are amongst the
latest novelties. A smaller
size of the well-known Vestal Vinolia Soap, three tablets in
a box, and retailing at 4s. (id. , has recently been added for
the convenience of those not requiring the
larger size. As our readers are aware, Messrs.
Blondeau supply some of their preparations
in decorated porcelain vases ; these can now
be obtained without lettering, so that when
the contents have been used the vases are
more suitable for ornamental purposes. A i§j
further concession to the convenience of Ife
consumers is that the Blondeau Perfumes
are supplied with sprinklers instead of
stoppers. There are now thirty-six varieties
in this series, and amongst the most popu¬
lar are white rose, violette cle parmes, and wood
violet. For those who require an antiseptic
dentifrice Messrs. Blondeau provide a Carbolic
Tooth Powder in (id. and Is. patent metal boxes. Violet Powder-
in a new style, put up in J-lb. tins, to retail at Qd., and anew
series of cheap Toilet Soaps, six in a box, and retailing at 2d. a
tablet, each with an embossed figure of Britannia, are also
amongst recent additions. The latest novelty is Savon Violette-
de Parmes ; both box and wrapper are tastefully decorated with
floral device, printed in violet, and forming a welcome addition
to the Favourite Perfume Soaps.
.
LACTOMALTINE.
A special feature of this preparation is that combined with tho
well-known properties of malt extract are incorporated milk and
cream, thus forming what the makers describe as “an ideal flesh¬
forming food,” containing, they claim, all the elements necessary
to make a “nutritious, palatable, and strengthening” preparation,
which surpasses cod-liver oil preparations by reason of its efficacy
and stability, the fats of the milk and cream replacing the oil.
The Lactomaltine Company, whose address is 35, Snow Hill,
London, E.C., also places it on the market in conjunction
with hypophosphites. Both preparations are well made and
presentable. The get-up of the packages is also attractive,
and the sticky corks in the uniquoly-misshapen bottles are neatly
covered with celluloid caps.
CHEAVIN’S MICROBE-PROOF FILTERS.
The filtering medium employed by the Fulham Pottery and
Cheavin Filter Co., Ltd. , is in the form of “ candles ” or bougies,
which are composed of a kind of unglazed porcelain of very fine
texture. They can be used as drip filters or as pressure filters by
suitable connections with a supply tap. An examination has been
made of one of the former, having a capacity of 2g gallons, and fitted
with five filtering tubes. This, when kept continually filled with
ordinary tap water, delivered filtered water at the rate of six
pints per twenty-four hours. The filter effects a complete-
Feb. 2?, 1837]
PHARMACEUTICAL JOURNAL.
197
separation of even the most minute suspended particles— yielding,
for instance, a colourless filtrate when finely divided ultramarine is
suspended in the water. Experiments on a pressure filter con¬
taining one filtering tube gave the following results. The water
pressure being equal to a column of mercury 16 inches in height,
filtered” water was delivered at the rate of three pints per hour. The
mechanical parts of these pressure filters are well made and finished,
and easily removed and replaced after cleansing. With regard to
its sterilising power the following experiments were conducted
with the pressure filter. The filtering tube was boiled in water
for one hour, afterwards being replaced in such a manner as to
avoid risk of contamination. The water, delivered at a pressure
equal to 16 inches of mercury, was then turned on, and 1 C.c. of the
filtrate added to separate gelatin culture tubes at the following
intervals
(1) One minute after turning water on
(2) One hour ,, ,, ,,
(3) Two hours ,, ,, ,,
The tubes were then incubated for five days at 37° C. , and all
gave negative results. A fourth gelatin tube inoculated with
unfiltered water from the same supply was turbid, and showed
abundant evidence of the presence of micro-organisms.
COD-LIVER OIL WITH HYP0PH03PHITE3.
Pharmaceutical skill is displayed to advantage in the excellent
emulsion prepared by Messrs. J. Robinson and Co., of Norwich.
It is of agreeable odour and taste, and not too thick to pour
easily. Yet the emulsion contains 66 per cent, of cod-liver oil.
Everything combines, therefore, to recommend the Norfolk
Emulsion of Cod Liver Oil with Hypophosphites as a first-class
pharmaceutical preparation, likely to be of great benefit by reason
of its tonic and nutritive properties.
TOILET SOAPS AND PERFUMERY.
Of the making of soaps, and converting them into toilet soaps,
there is no end, but the fact that each fresh lot of specimens ex¬
amined seems in some respect uncommon and therefore attractive
would appear to prove that in this direction, as in others, competi¬
tion is decidedly healthful. French soaps are usually most
attractive, but those prepared by Messrs. Bergmann and Co. , of
Dresden, are not likely to suffer by any amount of comparison.
The Almond Soap and Lily-Milk Soap may be singled out for
special reference, whilst the firm is also to be warmly commended
on the excellence of its extract Double d’Opoponax. Mr. L. Brager,
of 13, Grindlay Street, Edinburgh, is the British agent.
COCA-KOLA WINE.
A combination of the properties of coca, kola, and quinine is
offered by Messrs. Potter and Clarke, of Artillery Lane, E. , in
their Coca-Kola Wine ; which is attractively put up in half-pint
bottles to retail at one shilling each. The wine possesses all the
elegance usually associated with the firm’s preparations, and
appears to be at least as good as anything of its kind on the
market.
CYMRALIS WATER,
Natural mineral waters of home production should be widely
patronised if possessing sufficient merit, and the Cymralis Water
seems to meet every requirement of a pure table water. It is of
exceptional organic purity, contains a small proportion of
mineral constituents, and is very slightly alkaline. The water is
also aerated to the right degree, and is in no degree inferior to
foreign natural mineral waters. The proprietors are Messrs.
R. Ellis and Son, Ruthin, North Wales.
AUTOSPRAYS ANH AUTOCLAVES.
The Medico-Hygienic Inventions Company, Limited, of 63,
Queen Victoria Street, E.C., has quite recently been formed for
the purpose of introducing to pharmacists and the medical profes¬
sion such new inventions, etc., as represent the progress of modern
science, especially in its relation to the healing art. A good begin¬
ning has been made xvith two distinct novelties, viz. , Monnet’s Auto¬
sprays and Trillat’s Autoclave for disinfection by formaldehyde
vapour, the patent rights over the United Kingdom for both which
inventions have been secured by the Company. Mr. Michael
Carteighe is Chairman of the Board of Directors, the other members
being Messrs. Robert W. Greeff, Gustave Pertsch, and Heinrich
Helbmg (Managing Director). The Company looks for support
chiefly amongst chemists and the medical profession, to whom the
advantages of its products specially appeal, and they invite appli¬
cation from chemists who are willing to become sub-agents. The
autosprays are solutions of active medicaments in a liquid of low
boiling-point, and are contained in glass tubes having capillary
outlets, through which the liquid is capable of being forced by the
elastic tension of its own vapour. When nob in use, the orifice of
the tube is closed by an ingeniously-constructed metallic cap,
which effectually prevents loss by evaporation. On removing the
cap and inverting the tube a jeb of liquid issues as a fine spray,
Monnet’s “ Autospray” in Use.
which may be directed against any surface or into any cavity
requiring medication. The solvent evaporates immediately, leaving
the medicament (be it iodoform, carbolic acid, menthol or other
drug) distributed in a uniform layer and finely divided condition
on the surface which has been exposed to the action of the auto¬
spray. The solvent is practically uninflammable ; a stream of ib
may even be directed through a gas-flame without danger. A
great number of substances readily lend themselves to the method ;
amongst those actually in use may be mentioned collodium, carbolic
acid, corrosive sublimate, creolin, eucalyptol, iodine, ichthyol,
iodoform, naphthol, oil of mustard, resorcin, salicylic acid, etc.
The autospray is evidently more cleanly than the time-honoured
lotion or ointment, and the ease, readiness, and rapidity with
which ib may be applied are obvious advantages.
The second novelty pioneered by this company is the autoclave,
an apparatus for the disinfection of rooms and houses after infec¬
tious diseases by Trillat’s system of disinfection by formaldehyde
vapour. It is a well-established fact that formaldehyde, the germi¬
cide which rivals mercuric chloride in its inhibitory influence on
pathogenic organisms, acts to the greatest advantage when em¬
ployed in the state of vapour. Indeed, powerful as the disinfectant
properties of the commercial solution are known to be they do not
compare with the germicidal power of this agent when in the
gaseous condition. Hitherto disinfection of rooms has been brought
about either by diffusing formaldehyde solution in the form of spray or
by generating it in the apartment by the partial oxidation of methy-
lic alcohol in a specially constructed lamp. Both of these methods are
open to serious disadvantages in practice, nor is the evaporation of
the solution more satisfactory on account of the tendency of the
formaldehyde to polymerise on heating. The Autoclave, however,
in conjuction with the special liquid, now overcomes these diffi¬
culties, and affords an abundant supply of gaseous formaldehyde
free from aqueous vapour and the solid para compound. The prin¬
ciple of its action depends on the fact that when commercial formal¬
dehyde solution is heated in a closed vessel with a water-retaining
salb, such as calcium chloride, under a pressure of 45 to 60 lbs. to
the square' inch, pure formaldehyde vapour is freely disengaged.
198
PHARMACEUTICAL JOURNAL.
[Feb. 21, 1897
The apparatus manufactured in England by the Medico-Hygienic
Inventions Company consists of a strong copper vessel (capable
of withstanding a pressure of 150 lbs. to the square inch), sup¬
ported on a stand, and furnished with a stop-valve, thermometer,
pressure gauge, and removable cover, the latter being secured
by bolts and a rubber ring. Attached to the stop-valve is three
or four feet of fine copper tube of about 1/16 in. bore, the
object being to insert this in the keyhole of the apartment. The.
following is the usual method of disinfecting a room on Trillat’s
system : —The Autoclave having been filled to about two-thirds with
the patented solution formochlorol (commercial formaldehyde solu¬
tion and calcium chloride), the cover is screwed down, the petro¬
leum vapour lamp lighted beneath the apparatus, and the
exit tube inserted in the keyhole of the door of the apart¬
ment to be disinfected. In about half an hour’s time
the guage indicates a pressure of 50 to 60 lbs., the stop- valve is
then opened and the gaseous formaldehyde, as a blue vapour,
passes into tho room. After the expiration of an hour or more,
or when the evolution of vapour ceases, the tube is withdrawn,
the keyhole stopped, and the formaldehyde allowed to act on the
objects in the room for the space of five or six hours. Disin¬
fection may then be considered to be complete and the room
cleared by free ventilation. Formaldehyde vapour has been sho vn
by repeated experiments on the Continent to be most thorough in
its effects, for with the exception of a few very resistant non-
pathogenic organisms all disease- producing bacteria are destroyed
by ib. Under Trillat’s system the whole of the operations can be
conducted from the outside, so that the attendant is not compelled
to enter an infected apartment, nor need the furniture of the room
even be disturbed. Ordinary materials, all dyes in common use,
metal?, &c , are not affected or injured in any way by the action
of formaldehyde during the disinfecting process.
OBITUARY.
Bradley. — On February 14, Edwin Sylvester Bradley, Chemist
and Druggist, Ashbourn. Mr. Bradley had been a member of the
Pharmaceutical Society since 1869, and for the last twelve years
had devoted a great deal of time to the public service, being Chair¬
man of the Ashbourn Urban District Council and of several com¬
mittees of that body, Chairman of the Board of Guardians, and of
the Gas Company. He also represented Ashbourn on the County
Council, was one of the esteemed assistants of the Grammar
School, and also a member of the Governing Body of the School.
For well nigh a century and a half the family of Bradley has been
associated with not only the trade, but every good work in Ash¬
bourn, so that the news of Mr. Bradley’s death caused widespread
sorrow, reference being made to the sad event at all the places of
worship in the town . The funeral took place on Wednesday, the
17th inst., amidst universal regret. Aged 57.
Howe. — On February 16, Joseph Mason Howe, Chemist and
Druggist, Egremont, Cumberland. Aged 50.
Taylor. — On February 17, John Taylor, chemist and druggist,
Ipswich. Death occurred rather suddenly at Blakenham,
where he had gone for a day’s fishing. Shortly before five
o’clock he packed his fishing tackle and started along the tow-
path towards Claydon Station, but had not proceeded far when
he began to stagger. A man ran to his assistance, but he
gradually sank to the ground and died. An inquest was held,
and a verdict returned in accordance with the medical evidence,
that death was due to syncope of the heart. Aged 72.
PUBLISHERS’ NOTICE.
COVERS FOR BINDING.
Cloth gilt-lettered covers for binding the half-yearly volume of
the Pharmaceutical Journal are Supplied by the Publishers, at
a charge, including postage, of Is. 6d. each.
All Orders and Remittances should be Sent to the
Publishers, 5, Serle Street, London, W.G
NOTICES TO CORRESPONDENTS.
All Communications foi1 the Journal must, be Addressed to
the Editor, 17, Bloomsbury Square, London, and not in
any case to individuals supposed to be connected with
the Editorial Staff ; no responsibility can be accepted
unless this rule be observed. Communications for the
Current Week’s Journal should reach the Office not later
than Wednesday, but news can be Received by Telegraph
until 4 p.m. on Thursday.
Advertisements and orders for copies of the Journal must be addressed to
the Publishers, 5, Serle Street, Lincoln’s Inn, London. Choques and money
orders should be made payable to “ Street Brothers.”
Correspondents should write in ink, on one side of the paper only, and must
authenticate the matter sent with their names and addresses— of course
not necessarily for publication. No notice can bo taken of anonymous
communications.
Drawings for illustrations should be executed twice the desired size ; clean
sharp lines being drawn with a pen and liquid Chinese ink. Shading by
washes is inadmissible. Photographs can be utilised in certain cases.
Names and Formulas should be written with extra care, all systematic names
of plants and animals being underlined, and capital letters used to commence
generic but not specific names.
Reprints of articles cannot be supplied unless authors communicate with
tho Editor before publication.
LETTERS TO THE EDITOR.
Help for the Benevolent Fund.
Sir, — -In furtherance of the appeals which have already appeared
in tho Pharmaceutical Journal (pages 198 and 119) we would take
the opportunity afforded by the special issue to press home the
claims of the Benevolent Fund, on every one connected with the
trade — employers, assistants, and apprentices — and to again urge
in connection therewith, the special fitness of this present year
for a big effort to obtain increased subscriptions or donations to
this charity. We would suggest that local secretaries should solicit
the assistance of their brother chemists, so that personal appeal
may be made at every place of business and the necessities of the
Fund be duly set forth. We are satisfied that only good can result
from the adoption of such measures. Where there is no local
eecretary, surely some energetic and sympathetic chemist will rise
to the occasion and make it his special duty.
(Signed) Wm. L. Currie,
Local Secretary for Glasgow.
John Smith,
Local Secretary for Liverpool.
February A), 1S97. Harry Kemp,
Local Secretary for Manchester.
Sir,— I consider that I am quite sufficiently taxed — 2 l-v. to the
Society and 2s. 6 d. to the Benevolent Fund per annum — but
perhaps others would subscribe if the Fund was administered
differently. On the principle that “ those who will not work,
neither shall they eat,” I would say, those who will not contribute,
neither shall they participate or be eligible for assistance or
support out of the Fund. The 2s. 6 d. per annum is within the
reach of any willing subscriber, and yet as each voting paper
comes round we find about half of the “ recommended candidates
or applicants” are those whose records of subscriptions to the
Society or Fund are “blank.” Never in all the days of their
prosperity have they considered it worth while to contribute a
humble 2s. 6 cl. per annum, and yet when the dark days come upon
them, they fly for help to the very Fund which for so many years
they have ignored. It is not fair to the old subscribers that they
should be cold-shouldered to make room for those who have never
subscribed, but if every chemist will send his mite, this Fund will
lie greatly assisted, and we shall all have a title to its benefits of
which we may or may not need to avail ourselves. But while
A. B. and C. stand an equal chance of becoming an annuitant, when
only A. has lifted a finger to help on the Benevolent Fund, which
B. and 0. have ignored, it seems to me to offer little inducement
to would-be subscribers, and rather a recommendation to keep .tho
subscription in one’s pocket.
Portsmouth, February 20, 18971 Herbert II. Bailey.
Sir, — For some little time the question of how best to celebrate
this glorious reign of Her Most Gracious Majesty the Queen, with
special reference to the Benevolent Fund, has been engaging the
attention of my brother local and divisional secretaries in the
Fbb. 27, 1897]
PHARMACEUTICAL JOURNAL.
199
Midlands. And it is thought that the annual supper (held in
May) of the Midland Pharmaceutical Association should be
altered to a Benevolent Fund Dinner, to which ladies be invited
to be present. A special meeting of the Council is to be held at
an early date to consider the matter. In the meantime we shall
be glad if the wholesale houses and those gentlemen in the dis¬
trict who propose to give a special subscription or donation will
communicate their views to Mr. F. J. Gibson (president of the Mid¬
land Pharmaceutical Association), Wolverhampton, or to
Birmingham, February 22, 1897. Charles Thompson.
Local Secretary.
Solubility of Iodine in Cod-Liver Oil.
Sir, — Can you give me any information, or refer me to any
book, on the subject of the solubility of iodine in cod liver oil V
Does it combine chemically with the oil or only dissolve in it,
and does the solution keep unchanged ? If any of your corre¬
spondents will give their experience, I shall be extremely grateful,
as I have had to prepare some, and find it variable in its keep¬
ing properties.
Ventnor, February 20, 1897. M. Gibson.
A Minor Man’s Grievance.
Sir,— A brother in “ trade” — call it what you like, a “ trade ” it
is — when talking on matters pharmaceutical the other week, gave
me some rather startling facts concerning the manner in which
pharmacy is conducted in the West of Scotland. He has some¬
where about fifteen years’ experience, and having passed his Minor
exam. , lie sought out fresh fields and pastures new, with a good
object in view, viz., better salary. He applied to various whole¬
sale houses for a change, but met with no good results. He was
plainly told that qualified men were not much in demand in
the west, as the bulk of the dispensing, etc., was in the hands of
the medical men who kept open shop (with few exceptions) with
unqualified assistants. Having failed to attain his object, he
thereafter looked out for a suitable place to open a business on his
own account, and here again arose the same barrier. Now, what
inducement has any young man got to enter the pharmaceutical
line at all ? If company concerns (as we hear) are knocking things
all to sticks in England, then these doctors’ shops are the bane of
contention in Scotland, and to whom have we to look for redress ?
Apparently neither the Pharmaceutical Society nor the General
Medical Council is much inclined to interfere, and what object
has the Glasgow and West of Scotland Pharmaceutical Association
in view ?
February 23, 1897. An A. Ph. S. (82/28).
*x* The capacity of the Pharmaceutical Society to deal with the evils referred to,
must depend upon the extent to which it is a co-partnership of the trade.
If that were more generally the case the interests of chemists and druggists
might he protected even more effectually than those of the medical profession
can he protected by the General Medical Council.— [Editor, P./.]
On Check Tills.
Sir,— The very best till of the present day is the “ National
Cash Register,” No. 79. You press the button ; it does the rest,
as follows : — Displays the amount of customer’s purchase ; prints
a type- written receipt, which is dated and numbered ; adds the
total up as fast as the money is taken ; keeps a duplicate record of
every transaction on a separate roll inside. It keeps assistants
careful in handling the cash. The easiest and quickest till to use
after the first three or four days. It settles all disputes, such as
wrong change, etc. It costs £50. and is worth three times the
amount.
Torquay, February 23, 1897. E. A. Holloway.
A Case of Impersonation.
Sir, — A few weeks ago I engaged an assistant to manage a
branch business. I engaged him as a qualified chemist, and found
the name given on the Register for 1896, the address being a
large dispensing house in the West-end. I accidentally discovered
that he was not a qualified man, and that he was impersonating
his brother, who had passed the Minor but was now in a
foreign land. Inquiries at the registered address showed that the
qualified brother had left this large establishment some seven or
eight years, but no alteration had taken place in the address. It
seems to me radically wrong that a man should be allowed to use
an address which he has left for so long a period, and I think some
standing rule ought to be adopted in this and similar houses, that
all assistants leaving should immediately give notice of change of
residence to the Registi’ar. E vidently the annual communications
from the Society had been forwarded to some known address by a
friend at court. Such communications should, I contend, be re¬
turned to the Society, and ought to be plainly marked on wrapper
In case of removal return to sender. Failing this, I propose
that the Society should send a clerk round to all the large London
establishments previous to the publication of the Register to find out
all such cases, and that the provincial local secretaries should have
the responsibility of doing so in their districts. I have no doubt
there are numerous cases of impersonation going on in the country,
and I think that to avoid such cases some means of identification,
such as height, appearance, etc. , should be taken when successful
candidates get their certificates. If the statements of a former
assistant I had are to be relied upon, a certain chemist in a provincial
town is now carrying on business in his name, the latter being
qualified. I may say I have no means of proving this case, but
only repeat the statement made to me as an argument in favour of
some means of identification.
London , February 23, 1897. Chas. J. Rees.
*V* Our correspondent’s suggestion would very considerably increase the expense
involved in the maintenance of a Register, the whole of which is now borne by
subscribers to the Pharmaceutical Society, though as matter serving tli
general interests of the trade, it should be a charge on all registered personso
—[Editor, P.J. ]
Nitrous Acid in Aqua Destillata.
Sir, — In your latest and most useful departure, the “Students’
Page,” which, to use a hackneyed expression, supplies a long-felt
want, I observe it is stated last week that the starch and
potassium iodide test is to detect nitrous acid in aqua destillata.
That is so, but in a note communicated to the Edinburgh
Chemists’ Assistants’ and Apprentices’ Association {Ph. J. [3],
xx., 415) I expressed the opinion that the addition of a few drops
of acetic acid would be advantageous, as the test would then
detect nitrites as well. The present U.S.P. test is for nitrites,
and not for nitrous acid alone, and it seems desirable that we
should copy their example. This note is meant merely as a
slight amplification of your remarks under aqua destillata on the
Students’ Page.
Leith, January 22, 1897. George Coull,
The Alleged Conversion of Cinchonine into Cinciionidine.
Sir, — As soon as information of Koenigs and Husmann’s
important paper on this subject arrived at Howards and Sons
factory I repeated there the experiment described, using perfectly
pure cinchonine, and obtained the same yield of cinchonidine — 5
per cent. I cannot understand why Dr. Paul and Mr. Cownley
were unable to effect the transformation ; their fractionation of the
product before attempting to precipitate the cinchonidine tartrate
should not affect the result, and in other respects they appear to
have followed Koenigs’ method. The cinchonine I used was pre¬
pared from bisulphate, free from all other alkaloids, even from
hydrocinchonine ; it was crystallised from alcohol, and the alkaloid
left in the mother liquor, made into neutral hydrochloride, gave no
precipitate with Rochelle salt at the same strength used for pre¬
cipitating the cinchonidine afterwards produced. Cinchonidine
tartrate began to precipitate a few seconds after Rochelle salt
was added to the solution obtained by Koenigs’ process, and the
alkaloid obtained from it by soda was purified by conversion into
tetrasulphate. This crystallised readily from 10 per cent, solution
in* alcohol, and that fact alone is almost enough to prove its
identity.
Stratford, near London, E. , G. E. Shaw,
February 23, 1897.
Ferrous Phosphate.
Sir, — Without wishing to appear hypercritical, I should like to
point out what, from a commercial point of view, may be looked
upon as a serious objection to Mr. E. J. Evans’ suggested formula
for ferri phosphas. The present B.P. proportions are almost theo¬
retically correct ; therefore it seems wasteful to increase the quan¬
tity of sodium phosphate in the manner proposed. Further, rever¬
sion to the use of sodium acetate in place of the bicarbonate
appears to be a retrograde step, in view of the fact that Howie
has very completely shown the loss of ferrous phosphate that
resulted from using the 1867 process, owing to the solubility of the
ferrous salt in acetic acid. Mr. Evans’ process evidently makes an
excellent product, but it is not an economical one. When
we have a subject for investigation in the Conference Blue List
200
PHARMACEUTICAL JOURNAL.
[Feb. 27, 1897
entitled, “ Tlie Utilisation of Waste Products in Pharmacy,” it
behoves us to take every available opportunity of indicating how
waste may be avoided, although we may not be able to utilise the
waste product.
Leith, February 20, 1897. Georue Coull,
The Amateur Prbscriber at it Again.
Sir, — They are at it again ; this time there is a pair of them.
One is a party, male or female, presumably the latter, who writes
under the pen-name of ‘ ‘ Aunt Miranda ; ” the other is a lady called
Mrs. Minnie L. Dowie. My wife takes in, or takes out, a publica¬
tion called Woman’s Life, and sometimes when my gigantic intellect,
wearied with the labours of the day,1 requires a rest, I pick it up
to discover the very latest way of eating bananas, and whether or
not there is any prospect of the crinoline coming in again. In the
issue of February 13 1 came across the following gem “ A good
depilatory is ‘ Depilene,’ and may be .safely used and re-used, and
one of the best is — •
Calcium . . 6 draolims.
Auripigmentum . .. . . | drachm.
Amylum . 6 drachms,”
There can he no doubt that 1 ‘ Aunt Miranda ” has not the faintest
ghost of an idea what these three ingredients are. “ Minnie ”, in the
Weekly Scotsman of Feb. 20, also has a cacSethes for prescrib-.
ing metals, but her taste is more exclusively alkaline. In answer
to°a correspondent’s query regarding the taking out of marking
ink stains from linen, she recommends trying the following : — -
“ Dissolve 1 07.. potassium in 4oz. water ; and with a camel’s-hair
brush . . . ,” etc. In all human probability the first formula
was for calcium oxide, and the second for potassium cyanide. But
supposing that by some mischance the querist got possession of
1 oz. potassium and dissolved it in 4 oz. water, the question — whether
‘ 1 Minnie” would be responsible or not for the inevitable injury to her
fair correspondent’s features — might form a most interesting subject
for a law-plea. I think it high time that the legislature made it
penal for these amateur prescribers to scatter their mischievous
recipes broadcast through the country.
February 22, 1897. Locul.
ANSWERS TO QUERIES.
[Queries addressed to the “ Editorial Department, 17, Bloomsbury Square, W.C.,”
will be replied, to in the Journal as early as possible after receipt, but the Editor
cannot undertake to reply to them through the post, nor is it always possible to publish
answers the same week. Questions on different subjects should be written on separate
slips of paper, each of which should bear the sender’s name or initials. Readers
requiring working formula for special preparations, and intimating their icants to the
Editor, will be assisted as far as may bepracticablc. The word “parts," when %ised in
formulas, invariably indicates parts by weight. A nonymous queries will be ignored.]
Removing Inkstains from Paper. — The composition of ink
is so variable at the present day that it is difficult to advise you as
to what to use, the more so since your paper seems to be of a
delicate texture. In some cases the prolonged application of a
paste of citric acid gives good results, but it is apt to leave the
paper brittle. If the document is a valuable one you should make
some experiments on a similar piece of paper first. You might try
citric acid. If the ink is solely an iron gallotannate one you will
probably succeed. [ Reply to Scribo. — 78,43.]
Ferric Salicylate. — The colour of the solution of ferric sali¬
cylate depends greatly on the degree of dilution of both the iron
salt and the salicylate. When both are very dilute the colour is a
bright purple, hut if stronger solutions are used it is deep red.
You may obtain the salt by mixing salicylic acid with excess of
freshly precipitated ferric hydrate, then allowing to stand in a
warm place for forty-eight hours, then filtering off the solution,
evaporating to a syrupy consistence, and scaling. W e have not
been able to obtain the salt in a crystalline form, nor are we aware
that it has been obtained in that state. As it appears to be soluble
in acetone, you might try crystallising it from that medium. Pre¬
sumably the formula is Fe2(C7H503)6. [Reply to Minerals.— 79/3.]
Fruit and other Cordials. — You will find recipes for these in
Cooley’s ‘ Cyclopaedia of Practical Receipts,’ edited by W. North,
published by J. and A. Churchill. The articles you name are
enumerated under the head of Liqueurs, vol. II., pp 973 to 976.
You can borrow the work from the Pharmaceutical Society’s
Library. [Reply to D. A. — 80/10.]
Disposing of Old Clean Corks.— Probably these can be re¬
worked for some technical purpose, if you have enough of them
you will very likely be able to get a price. Send a fair sample to
Messrs. Bussey and Co., 200, High Street, Boro, S.E. , or to the
London Cork Company, Limited, 50 and 52, Haymerle Road,
Peckham, S.E., and state how much of the bulk you have.
Possibly some linoleum makers would buy of you if you have
plenty, say some tons. [Reply to L. O.— 79/36.]
Paste for Labels on Tins. — (a) Flour, 8 ounces ; sugar,
4 ounces ; boiling water, q.s. to make a stiff paste. While hot
add powdered corrosive sublimate, 2 drachms. Stir until nearly
cool. Label “Poison.” (b) Shellac, 2 ounces; borax, 1 ounce ; water,
16 ounces. Boil together until shellac is dissolved. In either case
the surface of the metal should be freed from oil by rubbing with a
cloth moistened in a solution of ammonia. [Reply ffiH. W.— 79/13. ]
Oil of Spike. — True oil of spike is obtained from Lavan¬
dula spica, a native of maritime Southern France, where its dis¬
tillation is an important industry. “Spike” is the corruption of
“aspic,” the colloquial French term. Much of the commercial
spike oil is little more than turpentine flavoured with the genuine
“ essence d’ aspic.” [Reply to J. II. S. — 79,37.]
Delivery of Journal. — We are glad to have the details of your
complaint as to the non-delivery of the Journal, and hope to hear
from you again, in case of any similar failure in delivery. [Reply to
Member. — 81/2.]
Acidity of Moorland Water. — The amount of acid that will
be volatilised in the steam generated in a boiler at 20 lbs. pressure
will be infinitesimal when dealing with even an “ acid ” moorland
water. The action of the water will be far more serious to the
boiler itself than to any other part of the system employed. You
should accurately titrate the acidity of the water from time to
time by means of standard alkali, and then add milk of lime in
such quantity per gallon as is indicated by the titration, or slightly
in excess of that quantity. Give preference to logwood as an
indicator, since the acid of moorland water seems most sensitive
to that. [Reply to Humic Acid. — 80/36.]
Mould on Extract. — Any vegetable extract is liable to become
mouldy if exposed to moisture and warmth. The pot cannot have
been properly closed. [Reply to S. H. — 80/30.]
Hop Ale Syrup for Aeration. — Essence of hop ale, 2 ounces ;
soluble essence of ginger, 1| ounces ; syrup, 9 pounds. Mix.
“ Syrup ” the bottles in the usual way before charging. If you
want to make a fermented hop ale add 5 gallons of water to the
above quantity of syrup, and ferment with a little compressed
yeast. — [Reply to D. A., 82/15.]
Tonic Syrup. — For a general tonic you cannot do better than
use ferri et quinime citras. The following will give you a tonic
syrup which is both elegant in appearance and palatable : —
Citrate of iron and quinine, 40 grains ; simple elixir, B. P. C. ,
4 fluid ounces ; simple syrup, 4 fluid ounces. Mix. Dose : One
tablespoonful for an adult, a dessert spoonful for a child.
[Reply to W. W. — 80/16.]
Petroleum Emulsion. — Liquid vaseline, 4 ounces ; powdered
gum acacia, 2 ounces ; glycerin, 1 ounce ; calcium hypophosphite,
72 grains ; sodium hypophosphite, 72 grains ; orange flower water
to produce 15 fluid ounces. Add the acacia to the oil in a mortar,
mix and add at once 5 ounces of orange flower water, rub well
until an emulsion is formed ; then add the hypophosphites
dissolved in 2£ ounces of orange flower water, to which the
glycerin has been added. [Reply to W. W. — 80/16.]
CORRECTION.
Dr. Matthew’s Steam Distillation Apparatus. — In the second
illustration of this apparatus, on page 134, the condenser tube D
should have been represented as dipping into the liquid G.
COMMUNICATIONS, LETTERS, etc., have been received from
Messrs. Adams, Arnott, Atkins, Bailey, Barker, Bennett, Bilson, Bird, Blythe,
Clarke, Cocks, Coull, Cowley, Cownley, Eberlin, Farr, Francis, Gibbs, Gibson,
Glyn-Jones, Goodall, Hill, Hogg, Holloway, Ingham, Jones, Kemp, Kirkpatrick,
Macfie, Macnaughton-Jones, Martindale, Miller, Morgan, Potter, Ranken, Rees,
Righton, Shaw, Simpson, Sowerby, Tasker, Tayler, Thompson, Wardleworth,
Wood, Wyleys,
March 6, 1897]
201
PHARMACEUTICAL JOURNAL.
THE PROD0CJION OFf AMPHORJN jjCHINA.
BY AUGUsVb£E\ M.A. ,
Corresiiondih^pftfethbcr of the Pharmaceu/ical Society.
\ S* /
The camphor tree, CiSt^anj/b^um^ camphor#, Nees et Eberm, is
indigenous to Japan, Formbaft, and thtf*8 central and southern
provinces of China. It has been known to the Chinese from ancient
times, but apparently until 300 or 400 years ago only as a valuable
timber tree.
The camphor first in use was undoubtedly the Malay
camphor, and, as Hanbury says (‘ Pharmacographia,’ p. 511), “at
what period and at whose instigation the Chinese began to manu¬
facture camphor from the camphor laurel is not known.” Hanbury
further states that “ the camphor of European commerce is pro¬
duced in Formosa and in Japan, and we have no evidence that any
is now manufactured in China, although very large trees, often
from 8 to 9 feet in diameter, are common ; for instance, in Kiangsi,
and camphor wood is an important timber in the Hankow market.’
The latest references to camphor production (‘ Index Florae
Sinensis,’ ii., p. 371) further would confirm this, viz., “ Kwang-
tung, common around Pakhoi, but not utilised (Playfair).” Again,
“Dr. Henry states that the wood is much used in Central China,
but no camphor is extracted.”
Until a few years ago, then, no camphor was produced on the
mainland of China, but it is interesting to note that the camphor
industry has been started in China, and that there are signs that
it will become important. This is all the more noteworthy, as
Formosa has become Japanese territory, and it seemed likely that
camphor would become an entirely Japanese article, not a desirable
contingency in view of the fact that the Japanese Government is
striving to establish a monopoly in the production of camphor in
Formosa, and has no doubt in contemplation the creation of a
large revenue by enhanced prices in the future.
For a history of the vicissitudes of the camphor trade in Formosa
itself the reader is referred to the Chinese I. M. Customs’ ‘Decen¬
nial Reports for 1882-91,’ pp. 439, 466. En passant, this is a most
valuable work for all questions connected with Chinese commerce,
the history of the treaty ports, etc. It is replete with
information of all kinds, and is illustrated with maps, plans, and
diagrams.
Growth of the Chinese Camphor Industry.
The growth of the camphor industry on the mainland of China
is shown by the following facts taken from various China Customs’
Yellow-books. From the ‘ List of Chinese Medicines,’ misc.
series, No. 17, which gives details of the trade in drugs of all
kinds for the year 1885, it appears that camphor was unknown as
a product of the mainland, except in the single province of
Chekiang, there being the small export that year from Ningpo of
25 piculs. Ningpo exported 32 piculs in 1889, 40 piculs in 1890,
and none since apparently. The Customs’ ‘ Trade Reports ’ for
the different years show the gradual appearance of camphor pro¬
duction in other parts. Kowloon exported 88 piculs in 1888, 106
piculs in 1892, 87 piculs in 1893. This was conveyed in junks, and
its provenance is doubtful, but it was perhaps from the province of
I^wangsi. Canton exported 122 piculs in 1893, 37 piculs in 1894,
and 237 piculs in 1895. This is Kwangsi camphor. The Pakhoi
Trade Report for 1894 states that the first record of the article was
in 1892 ; in 1893 the export was 23 piculs, which increased to
128 piculs in 1894, and “it comes from Lu-chuan, near Yii-lin-
chou, and is likely to grow in importance, as plantations in that
and other places in the neighbourhood are coming to the bearing
age.” In the Pakhoi Trade Report for 1895, the export is given
Vol. LVIII. (Fourth Series, Yol. IV.). No. 1393.
as 596 piculs, and the writer says that this gratifying increase is
due to the extended cultivation in Kwangsi. In Formosa only
old and enormous camphor trees are utilised, and I am inclined to
doubt of the existence of camphor plantations in Kwangsi ; the
camphor produced is more likely to be from old forest trees. The
Chinese at any rate did not plant any trees with a view to the
manufacture of camphor.
Export of Camphor from China.
In 1895 the exports of camphor from different Chinese ports
was : — Foochow, 187 piculs ; Amoy, 668 piculs; Canton, 237 piculs;
Kowloon, 68 piculs, and Pakhoi, 596 piculs. In the Fukien
province there aue large forests and camphor trees abound. Some
years ago a party of Japanese went into the interior of Fukien to
manufacture camphor, but nothing came of this attempt. The
Foochow export is probably the product of this province,
but that of Amoy is doubtful, as it may be Formosan camphor
smuggled over to the mainland in junks. The export of the other
three ports is produced in the Kwangsi province, and this will
probably grow into large figures if camphor continues high enough
in price to encourage the Chinese in its manufacture.
To sum up, the production of camphor on the mainland of
China is an affair of the last few years. It began in Chekiang, but
has practically ceased in that province. In Kwangsi it commenced
a short time ago, and promises to develop into importance. The
Fukien product is only trifling so far.
NOTE ON GLYCERINUM AMYLI.
BY JOHN HENRY PEARSON.
For some time past I have had occasion to make glycerinum
amyli according to the instructions of the British Pharmacopoeia,
and have found that after a time the glycerin and water separate
from the mass. I have invariably used wheat starch, although the
Pharmacopoeia admits of the use of wheat, maize, or rice, and does
not in this particular instance, or indeed in any instance in the
official preparations of starch, state which should be used, although
it is known that different products are obtained when different
starches are used. The preparation was introduced many years
ago by the late Mr. Schacht, of Clifton, and I am informed that he
usually used arrowroot, although in his instructions ( Pharm . J oum .
[2], viii. , 210) he does not state what variety of starch powder
should be used. The formula of the present Pharmacopoeia
is apparently based upon the work of Mr. W. Willmott,
which is recorded under the title of “ Notes on Plasma,”
in the Pharmaceutical Journal [3], ix., 815, but here, again, the
kind of starch is not specially alluded to. Mention is made of the
proneness to deliquescence of this preparation, which is the great
fault I have to find with it when used as a base. Now it seemed
to me that the remedy was to be found in a method suggested by
Mr. Boa (Pharmaceutical Journal [3], xii., 682) for obviating a
similar evil which attached to confectio sulphuris, namely, the
addition of a minute quantity of powdered tragacanth. I have
made experiments with this in view, and find that it is worthy of
recognition and a place in the official formula, for it is, in my
opinion, an undoubted success. The mass remaining homogeneous
and inseparable, while batches which have “gone wrong ha\e
been brought to their proper condition by the addition of a
judicious quantity of tragacanth, this amount being dependent
upon the uses to which the preparation is put by the prescribei.
For my purpose the use of one grain per ounce of finished product
was a sufficient quantity.
202
PH ARM AOEU TIC AL JOURNAL.
[March 6, 1897
THE DETERMINATION OF ALKALOIDS.*
NOTES ON SOME OF THE PHARMACOPCEIAL PROCESSES.
BY E. H. FARR, F.C.S., AND R. WRIGHT, F.C.S.
In treating of this subject, we intend to confine our remarks
chiefly to the determination of the morphine in opium and its
preparations, merely touching on certain other methods of
alkaloidal assay.
In the analysis of a drug like opium, containing as it does so
many alkaloidal and other substances, it must naturally be a
matter of difficulty to isolate and determine the precise proportion
of any single constituent present, and it is not to be expected
that any process can be devised to which no objection can be
raised.
The process, now official, has been subjected to much criticism,
and not infrequently, also, decried in certain quarters as inaccu¬
rate. For our own part we are inclined to think that for general
pharmaceutical use no better process has yet been published, and
we make this statement after comparing it with many others.
For pharmaceutical use a process should be as simple as possible
whilst retaining a fair degree of accuracy. Both these conditions
are fulfilled by the official process, but we think that in the next
edition of the British Pharmacopoeia it might be somewhat
amended, and thus made slightly more accurate.
We will now consider the various steps of the process and
certain precautions necessary to ensure the best results being
obtained.
In the first place 14 grammes of powdered opium and 6 grammes
of freshly-slaked lime are rubbed into a smooth and uniform paste,
with 40 cubic centimetres of water, then 100 cubic centimetres
more water added, and the mixture stirred occasionally for half an
hour, to facilitate the reaction of the lime with the various con¬
stituents of the opium.
In the next place 104 cubic centimetres are filtered off, that
volume of filtrate being supposed to represent 10 grammes of
opium after the action of the lime. In contact with lime, morphine
forms a soluble compound, whilst most of the other alkaloids
present do not, and the acid constituents form insoluble lime com¬
pounds. The filtrate, therefore, should contain the whole of the
morphine with small proportions of the other alkaloids, and a
little extractive matter amounting in all to 30 or 40 per cent, of
the opium used. Of course these soluble matters increase the
volume of liquid, and for that reason 104 cubic centimetres are
taken instead of 100. Naturally the exact amount would vary
with different samples of opium, but it would be superfluous to
determine the precise volume in each case, as the variation is not
important so far as our experience goes.
After the measured quantity of 104 cubic centimetres is placed
in the bottle 4 gx-ammes of ammonium chloride, 50 cubic centi¬
metres of ether, and 11 cubic centimetres of rectified spirit are
added, and the mixture shaken at intervals during half an hour,
then set aside for twelve hours. The ammonium chloride decom¬
poses the morphine compound with formation of calcium chloride
and ammonium hydrate, and liberation of morphine. Any of the
other alkaloids present are dissolved out by the ether, together
with traces of morphine, whilst the presence of the rectified spirit
in the aqueous layer enables the morphine to assume more readily
the crystalline form. The proportion of alcohol must not be too
high, because in that case more morphine would be retained by
the mother liquor, though at the same time the crystals produced
would be larger.
After standing for twelve hours the ethereal layer is removed
and the contents of the bottle rotated with a further quantity of
* Read before the Chemists’ Assistants' Association (see p. 218).
20 cubic centimetres of ether to ensure the removal of all bodies
soluble in that liquid. Finally the crystals of morphine are col¬
lected on counterpoised filters, washed with a little distilled water
and then di’ied, first by pressing between filter paper, then at a
gentle heat, and finally at 96° to 100° C., until it ceases to lose
weight, when the product is supposed to be anhydrous.
The opium used should be in very fine powder, though this is not
stated in the official directions. We have found that a loss occurs,
amounting sometimes to as much as 5 per cent, of the morphine
present, when opium in coarse powder has been used.
Though morphine is supposed to become anhydrous when dried
at 100° C. until constant, and Squire states so in his ‘ Companion to
the B.P.,’ such is by no means the case with the morphine obtained
in the B.P. assay process, though it may be so where the alkaloid
has been deposited from a solution containing a higher proportion
of alcohol (some large crystals of morphine prepared by one of us
in that way became anhydrous when dried in the water-oven for
1 \ hours). Dott has recently called attention to this fact in a note
published in the Pharmaceutical Journal and we can fully
corroborate his statement. Different samples operated upon by our¬
selves and dried in the water-oven until constant lost the following
further percentage when heated for an hour at 110° C. : — 1 '60, 5 ’44,
5 84, 5-93, 6-50, 174, 6’61, 5’31.
The dried morphine invaluably contains some impurity, and will
never neutralise the theoretical amount of standard acid.
There is, as we have already stated, a loss of morphine in the
mother liquor and ether from which it has been precipitated. This
loss amounts on an average to 1 gramme for every 100 cubic centi¬
metres of filtrate operated upon.
We shall presently show that if the foregoing sources of error be
eliminated from the process it will yield results very closely
approximating to those afforded by the best of other published
processes. We will now consider the case of extract of opium.
This preparation, consisting as it does of the soluble portion of
about twice as much opium, may be assayed like the drug, using,
however, but half as much to the same quantities of other
ingredients, and first dissolving the extract in a portion of the
water.
In the assay of the liquid preparations of opium, new
factors come into operation, and any process for the determination
of morphine in those preparations must take into consideration the
amount of extractive matter present, and the proportion removed
on treatment with the lime. Naturally these will vary in different
samples, so that any figure based upon them could be only an
average, and must not be looked upon as a constant quantity.
Some years since we published a modification of the B.P. pro¬
cess, adapted for the determination of the morphine in tincture of
opium, but we have since found that the results yielded by it are
slightly too high, owing to the liquid taken for analysis repre¬
senting more than its own volume of the original tincture, from
insufficient allowance being made for the loss of volume caused by
removal of extractive matter on treatment with lime. With a
slight modification to correct that error it yields excellent results,
and would be equally applicable to the assay -of the liquid
extract of opium.
The details are as follow : — Take 80 cubic centimetres of ther
tincture and evapoi'ate by a gentle heat until the volume is reduced
to about 20 cubic centimetres ; mix this thoroughly in a mortar
with 3 grammes of freshly-slaked lime, and dilute with water to
85 cubic centimetres, stirring occasionally during half an hour ;
then filter into a 4-oz. bottle having a wide mouth fitted with an
accurately-ground stopper, 50 cubic centimetres, add 2 grammes
of ammonium chloride, 30 cubic centimetres of ether and 5 cubic
March 6, 1897.]
PHARMACEUTICAL JOURNAL.
203
centimetres of alcohol ; shake well at intervals during half an
hour, then set aside for twelve hours. Next remove the ethereal
layer by means of a pipette, rotate the contents of the bottle with
a further 15 cubic centimetres of ether, and when the latter has
completely separated, remove it as before by means of a pipette
and filter through counterpoised filter papers placed one in the
other. Wash the filter with a little ether, and then let the residual
ether evaporate from the paper. Next collect the whole of the
crystals on the inner paper, rinsing the last portions out of the
bottle and washing the crystals with morphinated water until the
washings are colourless. Dry the crystals, at first by pressure
between folds of filtering paper, then at a gentle heat, and finally
at 110° C. for an hour, then weigh.
Take ’3 gramme of the crystals and dissolve in a slight excess of
jjj sulphuric acid and titrate back with jtj soda solution, using
litmus paper to indicate the end reaction.
To the amount of pure anhydrous morphine in the- total amount
of the crystals, as indicated by the titration, add ’05 gramme,
representing the average amount of morphine lost in the process.
The combined weights multiplied by two will be the percentage
of morphine in the liquid.
We append a table showing the relative results by the process
just given in comparison with those afforded by Dott’s and by
Teschemacher and Smith’s processes on five different samples of
tincture of opium.
Process followed.
Percentage of morphine found in the
samples.
•
A
B
C
D
E
Modified B. P. Process.. . .
1-06
1-03
1-10
1-02
1-05
Teschemacher and Smith’s .........
1-04
1-02
1-08
1-00
1-03
Dott’s . .
1-01
1-01
1-09
1-01
1-06
The Drying oe Alkaloids.
The question has been recently raised as to the drying of
alkaloids by the heat of boiling water. Hitherto this has been
the only official process, but it has been shown that in the case of
morphine at least the temperature thus obtained is not sufficient to
ensure the expulsion of all the water. In the case of the alkaloids
of cinchona and the salts of quinine, however, perfect desiccation
may be obtained, though this is accomplished by no means so
rapidly as when the air bath At a higher temperature is used. In
the case of alkaloidal residues and extractive matters, a great
deal depends upcn the way in which the drying is carried out.
If the round-bottomed dishes in general use are employed, and
care be nob taken to prevent it, the alkaloidal or extractive
matter collects at the bottom of the dish in a dense fused mass,
and desiccation under these conditions will take place very slowly.
On the other hand, if a dish with a flat bottom be employed,
the substance spreads itself out in a thin film over a large sur¬
face, and desiccation is rapid, rarely taking more than two hours.
The following results obtained on determination of quinine in
citrate of iron and quinine will show admirably the contrast : —
Weight at the end of each hour when
dried in the hot water oven.
vY eight after being heated
1 hour in the hot air
bath at 120° C.
1 hr.
2 hrs.
3 hrs. 1 4 hrs.
1
5 hrs.
6 hrs.
In flat dish . .
•447
•442
•442 j
•442
In round dish
•409
•446
•443 | -442
1
•441
•441
•441
Quininas Sulphas.
Mr. Cownley, in a recent paper in the Pharmaceutical Journal,
has pointed out the fact that the official sulphate of quinine is very
unstable and gradually loses water of crystallisation on exposure
to the air, until but two molecules are retained, when it becomes
constant. He also stated that when the anhydrous salt is exposed
to the air it rapidly absorbs two molecules of water. We take
this opportunity of corroborating his facts and supporting most
emphatically his contention that the sulphate with two molecules
of water should replace the one now official in the B.P.
As an instance of the rapidity with which anhydrous sulphate of
quinine re-absorbs water, we may mention that 1 gramme of the
salt exposed to the air by one of us in the laboratory absorbed
•015 gramme in seven minutes, so that it must be cooled in a desic¬
cator, and weighed as quickly as possible.
Quinin.e Hydrochloras.
This salt when dried is even more hygroscopic than the sulphate
In six minutes a quantity of ’026 gramme of the anhydrous salt
exposed to the air gained ’017 gramme, and in three hours it had
resumed its original weight with two molecules of water.
THE TEACHING OF BOTANY.
On the Desirability op Establishing an Institute for the
Teaching of Botany in the Royal Botanic Gardens.*
BY W. MARTINDALE, F.C.S., F. I. INST.
I gather from a short history published in our Quarterly Record
No. 36, 1888, by the late Secretary, Mr. W. Sowerby, that the
Royal Botanic Gardens were permanently established by Royal
Charter in 1839, on the present site, and that a Scotsman, Mr.
R. Marnock, who had been Curator of the Sheffield Botanic
Gardens, became the Society’s Curator, and laid out the grounds.’
Since then, through many vicissitudes, it has been truly said that
the Royal Botanic Gardens have done more for Botanical teaching
than any other in Britain, by supplying medical and other schools
of London with living specimens. On examining Mr. Marnock’s
work, one is struck with the admirable plan he adopted in laying
out the classified plants in natural orders grouped together
according to their affinities, as well as by the arrangement of the
trees and shrubs in groups which enabled the student to com¬
prehend systematic botany with greater facility than would be the
case in stiffly arranged parallel beds. In the graceful plots, in
varying patterns, representing the natural orders, he attempted to
convey to the student by their size the comparative number of
species which belonged to each order, thus the importance of the
orders which were capable of being so displayed was seen at a
glance.
My personal recollections of the Gardens extend back to the year
1863, when in the early mornings of that spring and summer I
attended the lectures and demonstrations of our late revered member
of the Council, Professor Bentley, who for many successive years
gave courses of instruction on structural and systematic botany in
connection with the Pharmaceutical Society. This, I understand,
is the nearest approach to systematic scientific teaching that has
been attempted' in the Gardens. Bentley had a love for his sub¬
ject, and inspired the same in his students. I began early the
study of field botany as an amateur, and, as it is necessary for my
calling, I felt the need of systematic instruction afterwards.
Botany is essentially a practical science, it requires specimens
to teach it, and in place of dissecting the often half-withered
specimens at some distance from where they have been grown, the
student could best utilise them by receiving his instruction, es¬
pecially on systematic and structural botany, in an institute which
might, for example, be established in these Gardens. He would
here see in great variety numerous plants for further study in their
natural condition. Typical specimens are a necessity for study,
and it is the search for these and the more or less rare species
which grow wild that creates the love for the science and adds the
charm to field botany. Who, as a botanist, has not in his botanical
rambles made life-long friendships ? And as the season now
approaches many will join in going to explore the “ bank where
the wild thyme blows.” My memory clings to an excursion made
with a friend to Highgate Wood a little later in the year than
this, in which we found Euphorbium lathyris and other to us then
unknown plants. We in imagination crossed the Rubicon at the
Read before the Royal Botanic Society (see p. 217),
204
PHARMACEUTICAL JOURNAL.
[Maech 6, 1897
bottom of the wood, and returned laden with a vasculum filled with
botanical spoils.
The utility of the science of botany is universal, and the study
of it should be more especially necessary to the agriculturist,
gardener, colonist and emigrant, medical and veterinary practi¬
tioner, and to the pharmacist, but the teaching of the science in
London has latterly been more neglected than it was even thirty
years ago, the reason of this being that for the medical examina¬
tions, more especially those of the Conjoint Board, botany is not
such an essential subject as it was formerly, a very elementary
knowledge being all that is necessary for any but tne university
and pharmaceutical examinations.
*■ Among the institutions in London teaching botany there are
those of the Royal College of Science (South Kensington),
University College, the Pharmaceutical Society, King’s College,
the Royal Veterinary College, the Birkbeck and Polytechnic
Institutes, the several medical schools of the hospitals, and a
number of private schools, but, except in the first few mentioned,
there is little efficient teaehi«g dorm, a»d none of them have
gardens attached ; therefore their facilities for teaching are
limited. It is true that at the Physic Gardens, Chelsea, there are
a dozen lectures given during the summer annually, but the scope
of their work is limited. These gardens grow most herbaceous
plants well, with the exception of some of the Rosacece and Cruci-
ferse.
This leads to the reflection, Why are our Royal Botanic Gardens
not more utilised for teaching purposes — I mean the systematic
teaching by lectures, demonstrations, and classes — as well as for
botanical investigations, for which they are so well adapted ?
I have visited several of the celebrated botanic gardens of the
world, that of Mr. Thomas Hanbury at Mortola, Sir Francis Cook’s
at Montserrat, near Cintra ; the late Asa Gray’s in connection with
Harvard University ; the Acclimatisation Gardens in the Bois de
Boulogne, and the Jardin des Plantes, Paris, as well as the
botanical gardens at Lisbon, Edinburgh, Glasgow, and Oxford, not
including Chatsworth and Wilhelmshohe, which may be taken as
purely ornamental gardens, but I was most impressed with those
at Marburg, in connection with the university. Here, when I
took my son to enter as a student, I noticed the admirable manner
in which the teaching of botany in its various branches is carried
out in the German University system. The completeness of their
scientific and technical training is in many respects worthy of our
admiration and imitation. It is to be regretted, therefore, that
with the excellent beginning our Gardens had, the Royal Botanic
Society has not more fully embraced the opportunities for scientific
teaching.
This leads me to the consideration of our proposal to establish
an institute for the teaching of botany, as well as for the promotion
of botanical research, in the Gardens, particulars of which I
submit.
Minute of a Scheme for Establishing an Institute for
the Teaching of Botany in the Royal Botanic Gardens.
With the opportunity afforded by a renewal of the lease of the
Gardens, the Council of the Royal Botanic Society is endeavouring
to resuscitate one of its functions, which in some degree from
want of funds has hitherto been imperfectly performed, that of
Education.
According to its Charter its main object was : — “ The promotion
of Botany in all its branches, and its application to Medicine,
Arts and Manufactures, etc.,” and the Charter was granted for
“ promoting the said science of botany,” which of necessity
includes education.
The Council therefore hopes to establish an “Institute of
Botany” in conjunction with its functions as Botanical Gardens,
entirely or partly under its own control, as may hereafter be
decided upon.
The Botanical Institute to be established would be similar to
those on the Continent, and the work done would be similar to
that performed by the establishments in Edinburgh, Dublin,
Oxford, and Cambridge, in connection with the Botanic Gardens
there, which institutions are under the control of the respective
Universities. In Germany, Switzerland, and Holland, several of
these Institutes are affiliated with their Universities, and they are
nearly always attached to or surrounded by Botanic Gardens, so
that students of the Institutes have the most ample opportunity
of studying plants in the living state. The Institute at Marburg
is surrounded by such gardens and conservatories, and similar
Institutes with gardens attached exist in Paris (in connection
with the Jardin des Plantes), in Berlin, and at Dorpat, Amsterdam,
Leyden, Groningen, as well as many others, not forgetting that at
Genoa, founded by Mr. Thomas Hanbury, and that in Paris in
connection with the Ecole Superieure de Pharmacie.
The functions of the Institute would be: — (I.) On the purely
scientific side, the practical teaching of botanical science in its
various branches, more especially in connection with vegetable
physiology, anatomy, histology, and pathology, as well as con¬
ducting scientific research on botanical subjects.
(II.) On the economic and technical side, the diagnosis of the
diseases and parasites of plants ; the estimation and the value of
timbers and their selection in regard to resistance to strain,
moisture and decay ; the study of vegetable fibres, their strength,
fineness and the methods of cleaning and preparing them from a
commercial point of view ; the methods of separating and gathering
indiarubber and gutta-percha, and collecting them as free from
extraneous matter as possible ; and the same in regard to gums,
resins, and drugs. These are points of great economic interest to
the colonist and emigrant.
(III. ) The study of grasses and cereals, as well as of cruciferous
and leguminous plants for the guidance of agriculturists ; and
of horticulture in its various branches for the gardener and fruit¬
grower.
(IY.) The study of the tea and coffee plants, as well as of
arboriculture generally, would also form part of the curriculum of
the Institute. The enormous colonial interest in these subjects
increases yearly, and they are of great importance to the whole of
the British Empire.
(Y.) Bacteriology as a separate study would probably not be
within its scope, except so far as it concerns botanical research,
the diseases of plants, and agriculture.
A special function of the Institute would be the teaching of
vegetable physiology — the study of living plants, and the working
of a physiological laboratory for botanical investigation to aid and
to meet the practical requirements of the colonist, the agriculturist,
the gardener, and the merchants who deal in tea, coffee, tobacco,
timber, drugs and vegetable products generally.
The Royal Botanic Gardens have at the present a museum,
lecture theatre, and small library and herbarium, which would form
the nuclei of larger collections in connection with the proposed
Institute.
Their easy accessibility from the railway stations and medical
schools, and their central and open position in Regent’s Park,
render the site of the Royal Botanic Gardens unique for the
purpose of plant culture, and the study of plant life by those who
have to pursue other studies simultaneously.
The need of a Botanical Institute for the purpose above men¬
tioned is greatly felt by colonists and those intending to emigrate,
who now go to Germany in considerable numbers to obtain instruc¬
tion. Many of these might profitably spend a session at a
Botanical Institute if such existed in or near London, as few of
them emigrate before they are of age.
It is to be regretted that London, whose wealth in great measure
is dependent on its importation and distribution of products from
the vegetable kingdom, offers little opportunity for the educational
study of the plants from which these are obtained.
Kew may be referred to as offering such opportunities, yet they
do not teach at Kew, but require trained workers, such as a
teaching Institute might supply.
The functions of the proposed Institute would not be the same
as those of the Imperial Institute, any more than of Kew. The
Imperial Institute undertakes the investigation of products ; prac¬
tical botany and the study of plant life are not within the scope of
its work.
London, as the great centre of the Empire, with its enormous
population and capital, is not like a small university town depend¬
ing on its students only, so that, if once established, the Council of
the Royal Botanic Society has every reason to believe that the
Botanical Institute would be an educational success. The medical,
pharmaceutical, and scientific schools would doubtless supply
many of its students.
Botany originally had its foundation on pharmacy, it was to
define accurately the plants for use by the herbalist and physician
that it sprang into the position of a science, and originally the
Botanical Gardens were known as Physic Gardens. Naturally,
therefore, pharmacists take great interest in Botany, and the
Pharmaceutical Society has been a liberal subscriber to the Royal
Botanic Gardens since their foundation.
Eventually, the Council of the Royal Botanic Society hopes that if
such a Botanical Institute be founded, it will become affiliated
March 6, 1897J
PHARMACEUTICAL JOURNAL.
205
with the London University, and be recognised as one of the
teaching schools in connection with the reconstructed university,
but whether the London University be reorganised, or not, the
Botanical Institute would still have a valuable field of labour, as
have all the other institutions that it is proposed to affiliate to the
University.
As an example of the need for the better study of botany, how
few agriculturists know the grasses of their pastures ; they are in
fact left to the birds or Nature to sow, or to the survival of the
fittest, which in many cases means the most unfit, or as they are
generally called, weeds. To combat this, the agriculturist requires
to know what grasses will form his best fodder. Little has been
done in this respect in this country compared with what has been
done in Canada, the United States, Belgium, Holland, and
Germany, and even by the Portuguese at Busaco.
The appointment of Director, Special Lecturers, Demonstrators,
etc., are matters of detail.
I have received letters from several eminent botanists and
professors expressing sympathy with the scheme.
Mr. Thomas Hanbury writes from Mortola, February 24 : — -
“ In answer to yours of the 20th enclosing minute of a scheme for
establishing a botanical institute in connection with the Royal
Botanic Society, I would say that so far as I am able at this
distance to judge, the plan appears to me to be admirable, and
worthy of active support from all those who desire to see proper
facilities given in London for additional botanical teaching. The
Botanical Institute I built at Genoa five years ago proves a
complete success, and is used by about 110 students on the average.”
Professor Arthur Meyer writes from Marburg, February 18
(Translation): — “I am pleased that you are about to give the
Science of Botany a new status in London. The plan you develop
in the scheme you sent me is very good, only under the heading of
‘Functions — Scientific’ in conjunction with practical teaching, I
should mention ‘ Scientific Research,’ for the reason that a good
Teacher must in every case be an Investigator, and in accordance
with this a few words concerning ‘ Scientific Research ’ should
be added. This addition would not cause the Institute to change
its aim, which should principally be that of Teaching. I should
be very pleased if you would send me a copy of the scheme in its
finished form, a- I take a very great interest in the matter.”
The functions of the Institute such as I have suggested would
in no way interfere with the gardens fulfilling the social objects of
the Society, and of being, according to the Charter, “extensive
botanical and ornamental gardens within the immediate vicinity of
the metropolis.”
In conclusion, I have not mentioned the subject of examinations,
a fact that a friendly critic pointed out with approval, as he con¬
demned the working for mere examinations as being a failure ;
still, although it is not contemplated that our educational work
should be for that object alone, yet no doubt our curriculum would
be obliged to adapt itself to the requirements of some of the
examining bodies.
Neither have I mentioned finance, but I think the wealth of
London, for example, the City merchants and companies, by setting
“ their heads and purses together (the two great forces of civilised
humanity) ” should come to our aid, and that a Government grant
might also be obtained, if the scheme be trustworthy and properly
supported.
In this year we commemorate the longest reign of any British
sovereign, that of Her Most Gracious Majesty, our Patron. With
Her Majesty here Flora jointly reigns, and annually our queen of
flowers, Victoria regia, makes a magnificent display.
Established almost contemporaneously with the accession of our
beloved sovereign, this Society has enjoyed her patronage from the
first, and in commemoration of the late Prince Consort, the most
illustrious of our past Presidents, I think the establishment of an
Albert Institute of Botany, a project which would have been after
his own heart, would be a fitting culmination of the work the
Society has been doing during the six decades of Her Majesty’s
reign.
Iodine Vasol “Hell” is a new iodine preparation for external
use, containing 7 per cent, of iodine organically combined. It
produces a mild and prompt iodine action without the local
irritation which results from the use of iodine tincture. Disagree¬
able odour and soiling of the linen are also avoided. Favourable
results from the preparation are reported from medical quarters. —
Zeitsch. d. cdlg. oester. Apoth. Ver., li., 53.
PHARMACEUTICAL SOCIETY
MEETING OF THE COUNCIL.
WEDNESDAY, MARCH 3, 1897.
Present :
Mr. Walter Hills, President.
Messrs. Allen, Atkins, Bateson, Bottle, Carteighe, Corder
Cross, Gostling, Grose, Hampson, Martindale, Park, Savory
Symes, and Young.
In the absence of Mr. Harrison, the Vice-chair was taken by Mr.
Hampson.
The minutes of the last meeting were read and confirmed.
The President said he had received a letter from the Vice-
President regretting his inability to be present that day on account
of a slight attack of influenza. He was sorry to say that the same
cause was keeping Mr. Newsholme away. He might also refer to
the sad bereavement which since the last meeting had befallen
their colleague, Mr. Johnston, of Aberdeen. He was sure every
one deeply sympathised with him in the greatest sorrow which
could happen to any man.
The Late Mr. Schacht.
The President read a letter he had received from Mrs. Schacht,
dated February 9, in which she expressed her heart-felt apprecia¬
tion of the very kind message of sympathy with herself and family
lately sent by the Council. She apologised for the delay in writing,
but said she could not allow any hand but her own to do so. This
gave him the opportunity of saying that at the meeting of the
General Purposes Committee on the previous evening there was a
very general desire expressed that they should have on the walls of
the Council Chamber a portrait of their departed and honoured
friend. One of their colleagues was in a position to say that there
was a very good portrait in existence, of which a replica could be
obtained for a comparatively moderate sum. Two gentlemen had
kindly undertaken to put the matter in operation, and he thought
it very probable that a number of Mr. Schacht’s friends would
like to join in the movement. He therefore mentioned the
matter in public, and had no doubt there would be an immediate
and hearty response.
Election of Members.
Pharmaceutical Chemists.
The following, having passed the Major examination and
tendered their subscriptions for the current year, were elected
“ Members” of the Society : —
Daniels, Herbert Joseph ; Dartford. i Morgan, Henry Brunt ; Waterloo.
Ellington, Charles Sampson ; Sutton. | Tunbridge, Francis F. A. ; London.
Chemists and Druggists.
The following, who were in business before August 1, 1868,
having tendered their subscriptions for the current year, were
elected “ Members” of the Society
Armitage, Nathaniel ; Leeds. | Sewelson, David ; Manchester.
Poulson, Edward ; London. ' Smith, John Fi'ederick ; Coed Poeth.
Uttley, William ; Hull.
Election of Associates in Business.
The following, having passed the Minor examination, being in
business on their own account, and having tendered their subscrip¬
tions for the current year, were elected “Associates in Business” of
the Society : —
Brown, Sidney S. ; South Molton.
Ellul, Lawrence ; Malta.
Ferguson, John ; Perth.
Ferriday, Alfred James ; Liverpool.
Gregory, William Joseph ; Ware.
Harsant, Frank Worsley ; Epsom.
Homer, Thomas William ; Leeds.
Wilson, Wl
Kelly, John Waterson ; Liverpool.
Leighton, Thomas Taylor ; Leyton.
Nurthen, Frederick William ; London.
O'Dell, John Denis ; Hull.
Roberts, Robert ; Carnarvon.
Shepherd, Joseph Henry ; Woodville.
Sutherland, Alexander ; Baltasound.
l ; Langlaagte.
Election of Associates.
The following, having passed the Minor examination and
206
PHARMACEUTICAL JOURNAL.
[March 6, 1897
gendered their subscriptions for
‘‘Associates ” of the Society : —
Anderson, James ; Dundee.
Buckley, James Arthur ; Blackpool.
Elkingtcn, Charles John ; Rugby.
Sturrock, James N.
the current year, were elected
Lennox, James ; Edinburgh.
Long, James Christmas ; Boscombe.
Saunders, Alfred Woods ; Maldon.
Law ; Linlithgow.
Election of Students.
The following, having passed the First examination and
tendered their subscriptions for the current year, were elected
“ Students ” of the Society
and it might be mentioned that the will bequeathing the legacy
was made many years ago, when the deceased was quite a young
man.
The President said he was very pleased to hear what Mr.
Carteighe had said with regard to their late friend Mr. Thomas. He
(the President) had not had the pleasure of anything more than a
slight acquaintance with Mr. Thomas, and was, therefore, all the
more pleased to think that one who was so well known amongst
them had been mentioned in this kind way by Mr. Carteighe who
knew him so well.
Report of Benevolent Fund Committee.
The report of this Committee included a recommendation of
grants to the amount of £32 in the following cases : —
Abrey, Richard B. Henry ; Battersea.
Alexander, Thomas B. ; South Shields.
Allen, Archibald Clive ; Lichfield.
Andrews, Bertram L. M. ; Royston.
Balfour, Andrew Common ; Jedburgh
Bazley, Bertie William ; Gloucester.
Burton, Harry Osborne ; Liverpool.
Chaff, Thomas Waycott ; Paignton.
Curtis, Herbert N. R. ; Brighton.
Davies, Ralph Cecil ; Milford Haven.
Delves, Charles Broughton ; Exeter.
Dodd, David ; Manchester.
Douglas, Mary Ann T. ; Edinburgh.
Elvery, Herbert F. ; Southampton.
Evans, John Richard ; Brierley Hill.
Glascock, John Laybank ; Norwich.
Griffin, Alfred Buckle ; London.
Hackett, John ; Shepherd's Bush.
Hartley, William James ; Blackpool.
ITowse, Leonard Augustus ; Croydon.
Hymans, Herbert ; London.
Jackson, Herbert ; Grimsby.
Jones, John Lee ; Ebbw Vale.
Williams, Josiah 1
Kermode, John William ; Castletown.
Low, John Hill ; Fraserburgh.
McCartney, Walter ; Darwen.
McGregor, James ; Cullen.
Melbourn, Newell Ewens ; London.
Miller, Donald George ; London.
Molson, Algernon Heauley ; Sleaford.
Perkins, George Mitchelson ; Evesham.
Phillips, Ivor Reginald ; Abergavenny.
Ramsay, Robert Sparks ; Dundee.
Reynolds, Frank ; Droitwich. "
Shaw, Samuel ; Whaley Bridge.
Siggers, Clement ; Colchester.
Simpson, Francis Ernest ; Bloxham.
Snow, Harris Charles ; Maldon.
Strang, Duncan ; Callander.
Tanner, William Edward ; Cheltenham.
Thomson, Charles Samson ; Ayr.
Th waits, George Rose ; Edinburgh.
Verrall, Ada ; Swanboro'.
Warren, George Hope ; Bournemouth.
Webster, Digby ; Chester.
Wilkie, John Matthew ; Montrose,
rm as D. ; Bradford.
The names of the following persons, who had severally made the
required declarations, and paid a fine of one guinea, were restored
to the Register of Chemists and Druggists
Thomas Wokes Carlton, High Road, East Finchley, N.
Thomas Watts Coslett, IT, Jamaica Row, Birmingham.
James Hood Thomson, 51, Beaconsfield Terrace, Northampton.
Several persons were restored to their former status in the
Society upon payment of the current year’s subscription and a-
nominal restoration fee of one shilling.
A former Pharmaceutical Chemist member (aged 69), who had a grant ast
year, and whose position is now worse than it was then. (Oxford.)
The widow (aged 64) of a registered Chemist and Druggist, whose husband died
in January. She is now recovering from the effects of an operation, and hopes
later to be able to obtain a situation. (London.)
A Chemist and Druggist member (aged 71), and subscriber to the Fund. Was
in business for twenty-five years but had to give up in 1891. (Mabletliorpe.)
The widow of a registered Chemist and Druggist (aged 56) who has had four
previous grants, the last in October, 1895. (London.)
One case was deferred for further information, and three others the Committee
declined to entertain.
Mr. Bottle (as Chairman of the Committee) moved the adoption
of the report and recommendations. There was nothing calling
for any special comment in the cases which came before the Com¬
mittee.
The motion was at once carried unanimously.
Library, Museum, School, and House Committee.
Library.
The report of the Librarian had been received, including the
following particulars : —
Attendance
January . '{Evening'::::::
Circulation of Books. Total.
January . 204
Total.
Highest.
367
23
106
14
Town.
Country.
101
103
Lowest. Average.
3 14
2 6
Carriage paid.
£1 7s. 10pi.
Donations to the Library had been announced ( Pharm , Joum.,
February 13, p. 127), and the Committee had directed that the
usual letters of thanks be sent to the respective donors.
The Committee had recommended that Collin’s ‘ Guide Pratique
pour la Determination des Poudres Officinales ’ be purchased for the
Library in London.
Museum.
The Curator’s report had been received, and included the fol¬
lowing particulars
Attendance. Total. Highest. Lowest. Average.
Report of Finance Committee.
The Secretary read the report of this Committee, which was of
the usual character, recommending various sums for payment.
The President, in moving the adoption of this Report, said there
was nothing calling for special comment. It would be noticed that
a statement was given of the expenditure of the North British
Branch during the year 1896. All he had to say with regard to that
was that they were much indebted to their friends, the Executive
in the North, for the careful way in which they had managed the
finances of the Society. With reference to the Benevolent Fund, they
had among the donations a legacy of £100 left by the will of their
late esteemed friend Mr. Thomas. There was a subscription
of twenty guineas from the Pharmacy Club, as well as a subscription,
£2 15s. 4c?., collected at the Annual Supper of the Students attending
the classes at the Royal Dispensary, Edinburgh, sent by Mr.
William Duncan, and also £3 collected at a conversazione of the
Glasgow Pharmaceutical Association, and forwarded by Mr. Laing,
of Glasgow. These indications of the interest taken in the
Benevolent Fund by various classes of chemists and under various
circumstances were very gratifying.
Mr. Carteighe said he was quite sure the Council would be glad
to receive the donation from the Executors of the late Mr. Thomas,
it having been sent free of legacy duty. Mr. Thomas was a
Divisional Secretary, and formerly a pupil in the Society’s School.
Although they were very thankful for the legacy, he thought it
would have been a good thing for pharmacy if he had been spared
for some years to exercise the considerable amount of abibty which
he possessed in its behalf. Mr. Thomas was attached to the
Society and had been left by his father in well-to-do circumstances,
.TaT1,ln™ /Day . 547 40 8 . 21
January . \ Evening . 41 8 1 2
Several donations had been received {Pharm. Journ., February
13, p. 127), and the Committee had directed that the usual letters
of thanks be sent to the respective donors.
The Secretary read the report of this Committee, which con¬
tained nothing but routine matters.
The President moved the adoption of the report and recom¬
mendations, which was at once agreed to.
The Annual Meeting.
It was resolved that the 56th Annual Meeting of the Society be
held on Wednesday, May 19, at 12 o’cl ck.
It was also resolved that the preparation of the annual report be
referred to the Library, Museum, School and House Committee.
The Sale of Calcium Carbide.
The President said a paragraph had appeared in the daily press
stating that certain regulations were being made with regard to
the storage of calcium carbide, and the Secretary had that
morning received a letter from the Home Office which he would
read.
The Secretary accordingly read a letter which had been
received from Colonel Majendie, dated March 2, enclosing a copy
of an order in Council (see p. 212) which would be published in the
London Gazette on that evening. With regard to the memorandum
which the Department proposed to send to local authorities on
application, copies had not yet been received from the printers,
but one should be forwarded as soon as received.
March 6, 1897.]
PHARMACEUTICAL JOURNAL.
207
The President added that the memorandum referred to in
Colonel Majendie’s letter was a document which was to be supplied
by the Home Office to local authorities on application, giving in¬
structions how the order was to be carried out. They were
promised a copy of that in a few days.
Mr. Symes asked if the idea in applying to the Home Office was
to ascertain whether the regulations which applied to the storage
of large quantity of this substance would apply equally to such
small quantities as might be kept by chemists.
The President said he could hardly answer the question at the
moment ; he merely wished to let the Council know that informa¬
tion had been sent from the Home Office, and the order in
Council had been furnished, but as it had only just been received,
he had not had time to look into it, and further information would
soon be forwarded.
Mr. Symes said he hoped that the point he had mentioned would
be kept in view. The Petroleum Acts contained certain regulations
which contemplated the storage of large quantities, and he believed
that on representations being made some slight modifications were
introduced in favour of chemists and druggists, enabling them to
keep small quantities of benzine which would otherwise come
within the Act. He hoped the same good offices would be invoked
in this case if necessary, so that unnecessary inconvenience might
not be experienced by chemists.
The President said the point mentioned by Mr. Symes should
not be forgotten.
The International Congress at Brussels.
The President read a letter which he had received from M.
Duyk, acquainting him with the fact that the Association Generale
Pharmaceutique de Belgique were organising the Eighth Inter¬
national Pharmaceutical Congress, to be held in the month of
August next, at Brussels, on the occasion of the 50th anniversary
of the foundation of that Society. The letter stated that the
Belgian Pharmaceutical Association numbered more than 700
members, and was one of the most ancient professional societies
in that country. The writer begged him to use all his influence
with his colleagues and the pharmacists of this country generally
to induce them to participate in the Congress. There seemed to
be some little doubt in his (the President’s) mind as to
whether this could rightly be styled the Eighth Inter¬
national Congress of Pharmacy. The Seventh Congress
was held at Chicago, and at its close, a Committee,
of which Mr. Carteighe was a member, was appointed to
make arrangements for the holding of the Eighth Congress.
He had asked Mr. Carteighe if he had been approached
on the matter, and he understood that he had not. He did not
wish to throw any cold water on what would be no doubt a
very interesting meeting, more or less of an international char¬
acter, but on the question of official recognition he thought he
should rather wait to hear what Mr. Carteighe had to say on
the matter. At the same time he was quite sure that
their best wishes went with their pharmaceutical brethren
wherever they were, and he took this opportunity of
carrying out the wishes of the writer of the letter,
in making known to his colleagues, and through the press to the
pharmacists of this country generally, that there would be a
Congress in August in Brussels, and to that Congress all pharma¬
cists were invited, and that a very cordial welcome awaited them
there. He also wished to congratulate the Belgium Pharma¬
ceutical Society on their fiftieth anniversary.
Mr. Carteighe said many of them had received a printed
circular with reference to this Congress, which he confessed
he did not quite understand. He did not wish to say any more
than that he hoped their friends in Belgium would have a suc¬
cessful meeting, and he knew that they would do all in their power
to make it a success. So far as he knew and had been able to learn
the Committee of the Seventh Congress had not been approached
in regard to the next meeting, and in that sense the Congress to
be held in August was not the ordinary successor of the Seventh.
It was usual in all such cases for representatives from one or two
different parts of the world to write to the President of the Stand¬
ing Committee to make suggestions as to the holding of the next
meeting. It appeared that there was just a little confusion among
their Belgian friends, and he simply wished to put himself right
as being one of the Committee, by saying that this Congress had not
been organised on any formal offer sent from Brussels, but never¬
theless lie wished them every success. The Presidents of the
various organisations in different parts of the world were a little
sensitive on matters of routine, and it might, therefore, save any
friction if he mentioned what he did.
Dr. Symes called attention to the fact that the British Pharma¬
ceutical Conference was also fixed for the month of August, and he
hoped that it would not be spoilt by the fact of the Congress in
Brussels being held in the same month.
Mr. Carteighe observed that the International Pharmaceutical
Congress was started with very much the same objects as the
British Pharmaceutical Conference. There had been a meeting at
Paris, Breslau, Vienna, London, Brussels, and St. Petersburg.
The invitation from Milan was withdrawn at the last moment with
the permission of the Standing Committee of the Sixth Congress.
General Purposes Committee.
The Secretary read the portion of this report which dealt with
the examinations (see page 210). It stated that the Committee
recommended the report of the Sub-Committee for adoption. This
report recommended (a) That the First examination of the Society
be discontinued after June, 1900, and that there be substituted in
lieu thereof the production of certificates of approved examining
bodies covering a wider area of preliminary knowledge. ( b ) That
after 1898 the fee payable in respect of the qualifying examination
be ten guineas, (c) That the modified bye-laws submitted by the
Sub-Committee for carrying these changes into effect be read a
first time at the Council Meeting on the following day.
The President said it would be remembered that last year a
resolution was passed by the Executive of the North British
Branch to the effect that the time had arrived for making the First
examination a more efficient test of a candidate’s general know¬
ledge. This resolution, being sent to the Council, was referred
to the General Purposes Committee, which delegated its considera¬
tion tq^i sub-committee, which, having gone very carefully into
the subject, reported last evening to the General Purposes Com¬
mittee to the effect which had just been read. The report dealt
practically with two subjects, the First examination and the fee
payable in respect of the qualifying examination, and on each of
these he would say a few words. The third suggestion
as to the bye-laws was merely the carrying into effect of
the other two. With regard to the Preliminary examina¬
tion, there was a general consensus of opinion that the time had
come when it should be taken in hand and, being of such import¬
ance — though he believed most persons were agreed about — it would
be well to say a few words upon it. In the first place, he would
refer to some words, probably written by Jacob Bell, which
appeared in an editorial paragraph in the Pharmaceutical J ournal
so long ago as January 1, 1848. The Preliminary was then called
the classical examination, and the writer of the article said, “ The
object of this examination is to ascertain whether the candidate
has acquired that elementary knowledge which is essen¬
tial as a ground work of the education of the phar¬
maceutical chemist.” Then after making some apology for
what he considered the comparatively moderate character of
the existing examination, which was then perfectly voluntary, in
very elementary Latin and arithmetic, he concluded with the
following words, to which he wished to draw special attention :
“ We hope that it will in process of time be found practicable and
expedient to extend the course of study required for this examina¬
tion, feeling persuaded that an elementary acquaintance with
physics and mathematics is of great importance, and that some
knowledge of modern languages might be added with advantage.
These views had been endorsed from time to time by thoughtful
members of the calling ever since, and as far as his experience went
the Council had never forgotten the subject ; but it was a matter
in which it was desirable, if possible, that the opinion of the whole
body should be unanimous. The examination was now generally
regarded as inadequate, and for several reasons. Education had
advanced in every class of life, and it was highly important that
the general education of the pharmacist should bt kept up to the
level of modern requirements. The qualifying examination had
also in recent years become more thorough and extended, and
there were large numbers of failures. It seemed to the C ommittee
very hard that young men should be led into taking up a calling
for which they were utterly unfit, and that it would be much kinder
to let them know by the nature of the Preliminary examination that
a very considerable amount of knowledge was required befoie
they could obtain the qualification necessary to carry on
business. This matter had been specially before the 1 harma-
ceutical World for the last three or four years, and in 1895,
when there was a special meeting of the Society to
203
PHARMACEUTICAL JOURNAL.
[March 6, 1897
consider some alterations in the bye-laws, the general conversation
turned mainly on the question of the Preliminary examination,
though it was not then dealt with. Again, in 1891, at a meeting of
the Chemists’ Assistants’ Association, a unanimous vote was passed,
after a long and interesting discussion, that the scope of the
Preliminary examination might well be extended. There had
also been discussions in Scotland at which similar resolutions
had been passed, besides the resolution which he had
already mentioned, which had led to the present inquiry. He might
also infer from the public utterances of the Government
Visitor of their examinations that they had his sympathies in the
matter. In his report in March, 1895, I)r. Stevenson said a large
number of candidates presented themselves who had but a very
defective education, and in March, 1896, he said that the weak¬
ness in Latin and arithmetic of some candidates even who passed,
manifested itself at the later and more important qualifying ex¬
amination. All this showed that there was a feeling abroad
that the present Preliminary examination was not up to the re¬
quirements of modern times, and he might also refer to the
numerous letters which had appeared in the Pharmaceutical Journal
during the last few years. There were two ways of dealing with
this examination, it could be made more stringent in the present
subjects, or the scope might be widened. The first
was soon brushed aside by the Sub-Committee, feeling
that though it might keep a few more doubtful men out, it
would not do what was really desired — attract young men of better
general education into the calling. There was a general consensus
of opinion as to the advisability of widening the area of the
examination, but when they came to matters of detail there was
not quite the same agreement. He thought, however, that the
Committee had adopted a wise course, considering what was
required by other bodies ; it was decided that the examination for
general education required by the General Medical Council was
the one which would best meet the case. The fresh subjects which
it would introduce were Euclid (first three books), algebra (simple
equations), and a modern foreign language. This examination
could not only be recommended on its merits, but by adopt¬
ing it the young men who passed it would be in a position,
if they desired, to enter the medical, dental, or veterinary profes¬
sions, and the Institute of Chemistry, without having to pass a pre¬
liminary examination in arts. He was lately informed that a large
number of young pharmacists made inquiries at the General
Medical Council on this point, and he found that up to a certain
time the Preliminary examination of the Pharmaceutical Society
was recognised pro tanto for the medical preliminary, but it would
no longer be recognised in any way. It was obviously impossible
to conduct an examination in six subjects on one day, and the
Committee therefore thought it would be wise for the Society to
at once give up conducting its own Preliminary examination, and
hand over the duty to properly constituted bodies, whose special
function it was to conduct such examinations. The College of
Preceptors carried out four such examinations yearly, two in
June and December in London, Birmingham, Bristol, Leeds,
Liverpool, and at other centres as required ; and in March and
September at a very large number of centres. He had before him
a paper showing that at Christmas last these examinations were
held at over one hundred centres, and there would, therefore, be
no insuperable difficulty in the way of young men getting
examined. The question would, of course, be raised, though not
probably in that room, whether the game was worth the candle.
He would say, in the first place, that it was not fair to induce young
men, deficient either in mental power or education, to apprentice
themselves to a calling, only to find later on that they were unable to
obtain the qualification which the law prescribed. Even in the Pre¬
liminary about 50 per cent, usually failed, and the same might be
said of the Minor ; and a considerable number, therefore, after
trying in vain to pass the examination, remained unqualified
assistants to the end of their days. If the result of the proposed
change was to induce a better class of men to enter the calling, and
so encourage better education amongst those who proposed to enter
pharmacy, he thought the failures in the qualifying examination
would very soon diminish in number. On the Continent the
standard of preliminary knowledge required was much higher than
in England. In France anyone who wished to become a first-class
pharmacien had to pass a very high-class examination which
included English, mathematics, algebra, physics, etc. In Germany
before a young man could enter for the assistants’ examination,
he had to go through a three years’ curriculum in one of the
gymnasia, and in Russia the standard of preliminary education
required was equivalent to the matriculation examination for the
London University ; in fact, in the case of Professor Greenish,
the authorities at Dorpat would not receive the matriculation
certificate of the London University, showing how stringent they
were. With regard to Scotland, he held the College of Preceptors
were prepared to conduct examinations there if desired, but there
were several other bodies who undertook this duty whose
certificates were accepted by the General Medical Council, so that
there would be no difficulty in the way of their Scotch
brethren. He need hardly say that there were various
examinations accepted other than those of the College of
Preceptors. He had in his hand a long list of those
accepted by the Medical Council, and of course the Council
would accept them also. It was not proposed that this
alteration should come into force until after June, 1900, because
it would not be fair to interfere with the interests of any
young men who had already entered the calling. Passing now to
the second recommendation, that after 1898 the fee payable by
candidates on entering for the qualifying examination should
be ten guineas, the Committee had come to the conclusion
that as this included not only the examination fee itself,
but also registration for life, five guineas was altogether
inadequate. It must be remembered that the majority
were content with the Minor examination, and of those who passed
it about four-fifths were not in any way connected with the Society,
and did nothing to support it. At the same time they were regis¬
tered for life, and their interests were looked after by the Society
as well as those of its members and Associates. Every prosecu¬
tion instituted by the Society in accordance with the Act of Parlia¬
ment and in fulfilment of a public duty was more or less an
advantage to all those on the Register, but, unfortunately, most
of them were not connected with the Society, and it was only fair,
therefore, that the fee should be raised to the sum mentioned.
In the medical profession there was a registration fee for life in
addition to all the examination fees, and in the legal profession a
considerable sum had to be paid annually. He hoped he had said
sufficient to show generally what were the feelings of the Sub-
Committee and the General Purposes Committee with regard to
the point. The number of new bye-laws looked rather formidable,
but he had called attention to practically the only two points
which required special consideration. In the matter of the Pre¬
liminary examination he took the greatest possible interest, and he
was exceedingly glad that it had fallen to his lot to move that the
amended bjm-laws be read a first time.
Mr. Carteighe, in seconding the resolution, said he did so with
great pleasure, because he had been associated with the subject
very intimately for the last fifteen years. He had had opportunities
of addressing his brethren throughout different parts of the
United Kingdom a few years ago when the question of whether
education was worth the candle was frankly discussed. He had
succeeded in showing at every meeting he attended that education
did pay in a purely commercial aspect. If there was any opposi¬
tion to a change of this kind it would be by those who were unable
to appreciate the fact that it was not possible in these days to suc¬
ceed in any calling in life without a fair amount of education. The
raison d’etre of their calling was that they should possess an amount
of technical knowledge superior to that of their customers. It was
due to those who were upon the Register that those who came after
them should have the requisite knowledge. The students were
required to have an elementary knowledge of chemistry, physics,
and botany, and it was absolutely impossible for anyone to com¬
prehend the most elementary text-books, unless his preliminary
knowledge was greater than the three subjects at present
required, viz., Latin, arithmetic, and English. The fatal
objection to the old Preliminary examination was that youths
imagined that they could be crammed for it, and it was
obvious that the smaller the number of subjects the easier it
was to cram for an examination. The object of the Preliminary
examination was to see that the candidate had general knowledge
of the ordinary school subjects, and if he had not that knowledge
he had better not come into pharmacy. He did not look despond-
ingly on the future of pharmacy ; though no doubt the number of
retail pharmacies in which a large business was done was smaller
than it was thirty years ago ; still, from his own experience, he
must say that the prospects of the registered chemist and druggist
were distinctly better than they were thirty years ago. He believed
the average income of a chemist to be better, though he could not
prove it, and he believed there was a good professional livelihood
to be made in the future as in the past, notwithstanding the
March 6, 1897]
PHARMACEUTICAL JOURNAL.
209
amount of competition by companies, by the young man who
entered the calling with proper preliminary training, and who was
willing to work. The opinions of all thoughtful men went to show
that the best test of preliminary knowledge should be a wide one,
and not exact too great an amount of knowledge of each subject ;
in fact to adopt as far as possible the tests of those subjects that
would be taught in ordinary schools. The next point was that there
had been until recent years a strong tendency on the part of
corporations to retain all the power in their own hands with regard
to the Preliminary examination, as well as the others. This had
been generally abolished now, and in future regulations in regard
to universities he had no doubt it would be made a disqualification
that a body like theirs, which carried out technical examinations,
should also be able to examine in arts. The Apothecaries
Company was the latest survival of the Medical Corporations to
have a Preliminary examination, but that he believed was
either going or gone. Then, again, it was a mere
farce to say that the Society conducted the Pre¬
liminary examinati m even now, because it was really being
done by the College of Preceptors, and it was now proposed
not to pass it on to that body specially, but to all the examining
bodies which did that kind of work. It might be said that the
number of these bodies was not large, but practically they
could get any amount of that kind of work done if they
had sufficient candidates. In Scotland, the Institute of Scot¬
land, which was a body corresponding to the College of
Preceptors, was actually doing the same kind of work, and gave
facilities for examinations practically all over Scotland.
It would be recognised by the Government that the Society had
done a wise thing when they ceased to interfere with the general
education of the candidates, and accepted the certificates of
bodies specially chartered to do this particular kind of work.
The list of subjects looked formidable, but was only what any
pharmacist would think ought to be added to the existing
three. In Ireland elementary chemistry was included in the
Preliminary examination, which was far superior to the English
examination, and if they succeeded in getting a high standard
of candidates, they were to be congratulated in the course
they were pursuing. In choosing the subjects of the
examination it was considered desirable to make it of such a
character that the certificate when obtained would enable the
recipient to pass the portals of other professions in addition to
their own. The time had gone by when they could afford to
sit in a pharmacy and watch other people working for them.
They had now to work for themselves, and that being so,
in the interests of humanity they ought to insist that those
who were going to fight the battle of life on this field should
be properly equipped for the combat. As to the fee for the quali¬
fying examination, he advocated many years ago the payment of a
registration fee, and tried to persuade his then chief, Mr. Sandford, to
impose one, but was not successful. It appeared to him that everyone
coming on the Register ought to contribute to the expense of
conducting pharmaceutical affairs. A registration fee of five
guineas was exacted by the General Medical Council, and he
thought they had a right to ask the same. A great deal of the
past work of the Society had been of advantage to all registered
men, and so would be its work in the future. He could imagine
many questions arising, in which the Pharmacy Acts would be
involved, which would put the Society to great expense,
and all those who benefited by its action ought to contri¬
bute in some measure to that expenditure. But apart from
all that, the name of every man on the Register was
published annually, and he was protected in many ways,
for which some acknowledgment might fairly be asked.
If they valued their calling cheaply, they would themselves be
valued cheaply. He appealed to all thoughtful men throughout
the country who took an interest in the future of pharmacy to
forget their early struggles ; and he would impress upon all those
who raised the cry of cui bono that it was for the young men to
decide these questions.
Mr. Hampson supported the new bye-laws in their entirety, and
regretted that the Scotch members were not there, because he was
sure they would have heartily supported the resolution. He looked
upon the increasing of the fee as a necessity in view of the greater
responsibilities of the Society and the need for the sinews of war to
be strengthened.
. Mr. Martindale also supported the resolution, especially with
regard to the part relating to the Preliminary examination. He
did not think that the proposed increase in the fees was a very
harsh matter when they considered what was being done in other
bodies. The effect would be that the candidates would come
better prepared for the examination, and the fee being ten guineas
they would not care to leave much to chance. The examinations
under the present system scarcely paid their way, as although the
fees received would cover the expense of the examiners, there was
not much left for the larger buildings that had been required, so
that the additional charge for the qualifying examination was a
fair and just one. It might be thought that they would be shutting
out men from coming into the trade, but the numbers who came
up for examination negatived that idea. Even the public cried
out that there was a chemist at every corner.
Mr. Symes said he thoroughly approved of the proposed altera¬
tions. He might refer to the fact, which might perhaps be lost sight
of, that several other bodies besides the College of Preceptors held
examinations, so that under the new bye-laws the facilities offered
would be quite as great as at present. He could not conceive
there being any real opposition to this proposal. It was well
known that men who knew a great deal about one or two sub¬
jects were not those who succeeded best, but rather good business
men with a good all-round knowledge. It was obvious that as
their examination had remained practically the same for fifty
years, while in every other direction large advances had been
made, they were much behind the times, and unless some
improvement were introduced pharmacists would lose. the confidence
which the public had hitherto reposed in them as educated men.
He heartily approved of discontinuing the Preliminary examination
on their .own account. It had often been his lot to officiate as
superintendent, and his experience was that those who passed were
generally boys fresh from school, whilst older men came up again
and again and sometimes did not pass at all. It was quite clear
that this examination should be passed immediately on leaving school,
and should be regarded as the conclusion of the scholastic period,
rather than as a portion of the professional training. With regard to
the increased fee, it was well known that he advocated that every
man who passed the examination should become a member of the
Society, and should pay an increased fee in consideration of his
membership. He wanted every man who qualified as a pharmacist
to come into closer connection with the working of the Society,
and to feel that the work done by it was not merely for the sake
of its own members, but for the benefit of the craft at large.
Mr. Atkins wished to record his emphatic support of the pro¬
posed alterations, which he thought were necessary to keep them
on at all parallel lines with the movement of education outside.
The Society would become fossilised if it did not move forward.
They had the credit, which he thought they deserved, among
the traders of the country of being the most educated, and it
would be a most disastrous thing if they sacrificed that position.
He thoroughly agreed with widening the area rather than in¬
creasing the depth of the subjects touched upon. The only thing
he would join issue with Mr. Carteighe upon was his optimistic
views of the prospects of the trade. He believed the initial test
which they now proposed to strengthen was a most merciful
thing, and it was only right to inform candidates generally,
that only those who were educated in every sense, both educa¬
tionally and technically, could enter the business.
Mr. Allen also supported the resolution, and spoke of his experi¬
ences when superintending the Preliminary examinations, at which
the schoolboy was conspicuous by his absence, the majority being
men of over twenty-one, who were hopelessly puzzled by the
simple questions put before them. The effect of passing the new
bye-laws would be to compel the Preliminary examination to be
gone in for at the schoolboy stage. If they wanted to know
whether the Preliminary examination as now conducted was suffi¬
cient they had only to ask their own students, who would one and
all say that if they had been compelled to pass the proposed
examination they would have been better able to understand their
after studies.
Mr. Bottle said on no occasion had he felt greater satisfaction
than he had now in supporting a resolution for a proposed amend¬
ment. He looked upon the widening of the Preliminary examina¬
tion as being the best thing they could introduce in the interests
of the candidates. It would not only give them an advantage in
their progress in pharmacy, but it also opened the door to them in
dentistry and veterinary.
The President said he did not wish to curtail the discussion,
though he was glad to find that it had been all on one side, every¬
one agreeing that the proposed changes were wise and prudent.
He was glad Mr. Symes had called attention to the fact that the
210
PHARMACEUTICAL JOURNAL.
[March 6 1897
College of Preceptors was not the only body whose examinations
would be available to candidates. With regard to the point raised
by the same gentleman as to compulsory membership, it could
not be effected by bye-law, and he feared there would be some
difficulty in getting power from Parliament to carry it out. But
apart from that, his view was that if a better educated class of
young men were induced to enter the calling they would be
likely to support the Society which had done so much in the past
to promote education in its widest form, and that, as time went on,
a larger and larger proportion of those who passed would become
loyal supporters of the Society. They might be assured that
whether the qualified men subscribed their guineas or not, the
Council would go on trying to do their best in the public interest,
and with that public interest was involved the interest of every
man on the Register. In conclusion he moved formally that the
amended bye-laws be read the first time in accordance with the
provisions of the Charter.
The motion was carried unanimously.
The Council then went into Committee as usual to consider the
legal portion of the Committee’s report. This included a report
from the solicitor as to matters in hand, and recommended proceed¬
ings in certain other cases which had been reported to the Com¬
mittee.
On resuming, the report and recommendations of the Committee
were adopted, and special resolutions were passed authorising the
Registrar to take' proceedings against the parties named.
PROPOSED NEW BYE - LAWS.
Present By e= Laws.
Stat. 11. All persons who shall tender themselves to” the
1852, Examiners for examination in accordance with the Charter
sec' vm' and the Statute, 1852, or the Act, 1868, shall be examined
in their knowledge of the Latin language, in English
Grammar and Composition, and Arithmetic, which Exami¬
nation shall be called the First Examination. Such of the
said persons as shall desire Certificates of competent skill
and qualification to be registered as Chemists and Drug¬
gists under the Act, 1868, shall be examined in or produce
certificates of having previously passed in the First Exami¬
nation, and having been registered as Apprentices or
Students, and shall be examined in the translation and
dispensing of Prescriptions, in Botany, in Materia Medica,
in Pharmaceutical and General Chemistry, Physics and
Posology, and in their knowledge of the law relating to the
sale of Poisons, which examination shall be called the Minor
Examination ; and such of the said persons as shall desire
Certificates of competent skill and qualification to exercise
the business or calling of Pharmaceutical Chemists shall
produce Certificates of having been previously registered
as Chemists and Druggists, and shall be examined in more
extended knowledge of Bo' any, Materia Medica, Chemistry,
and Physics, or any two of them, which examination shall
be called the Major Examination.
Act 1868, 12. All persons who shall tender themselves to the Ex-
see. vi. aminers for examination, under the provisions of the Act,
1868, excepting only those specified in the next following
Bye-law, shall be examined in the Minor Examination.
Act 1868, 13. All persons entitled to be registered as Chemists and
sec. iv. Dmggists on passing a modified examination, who shall
tender themselves to the Examiners for examination under
the provisions of the Act, 1868, shall pass the Modified
Examination, which the Council of the Pharmaceutical
Society, with the consent of the Privy Council, have
• declared to be in their case sufficient evidence of skill and
competency to conduct the business of a chemist and
Druggist, as the same is set out in the Schedule hereto, or
such other modified examination as may in like manner be
declared such sufficient evidence.
Act 1868, 14. The Examiners may grant or refuse to such persons
sec. vi. ag }iave tendered themselves for the First Examination, the
Minor E xamination, and the Maj or E xamination respectively,
as in their discretion may seem fit, Certificates of com¬
petent skill and knowledge and qualification ; and lists of
such persons shall be delivered by the Examiners to the
Registrar.
Charter, 15. All persons shall, before registration as Apprentices
Act 1868 ’ or Students, pay a fee of Two Guineas and pass the First
aec. vii. ’ Examination, whereupon they shall be registered as
Apprentices or Students*
Proposed Bye=Laws.
11. Prior to July, 1900, persons desiring certificates of competent
skill and qualification to be registered as Chemists and Druggists
under the Act 1868, shall be examined in their knowledge of the
Latin language, in English Grammar and Composition, and
Arithmetic, which Examination shall be called the First Examina¬
tion. Persons intending to present themselves for this Examination
shall give to the Registrar notice in that behalf and pay a
fee of Two Guineas not less than 14 days prior to the day which
has been appointed for the holding of the said Examination.
All persons who pass the said Examination shall be registered as
“Apprentices or Students.” After June, 1900, persons desiring
the said certificates of competent skill and qualification under the
Act 1868, shall deliver to the Registrar on behalf of the Board of
Examiners a certificate of having passed an Examination in English
Grammar and Composition, in the Latin language, and in one
modern foreign language, and also in Algebra, Arithmetic and
Euclid, conducted by any or either of the examining bodies which
shall have been previously approved for the purpose by such
regulations as are specified by the last preceding Bye Law, and
shall pay a fee of Two Guineas, whereupon, if the Board of
Examiners shall so see fit, they shall be registered as Apprentices
or Students.
12. Persons intending to present themselves to the Examiners for
examination in accordance with the Charter and the Statute, 1852,
or the Act, 1868, and having been registered as Apprentices or Stu¬
dents, shall be examined in the translation and dispensing of prescrip¬
tions, in Botany, in Materia Medica, in Pharmaceutical and General
Chemistry, Physics and Posology, and in their knowledge of the
law relating to the sale of poisons, which Examination shall be
called the Minor Examination.
13. Persons desiring certificates of competent skill and quali¬
fication to exercise the business, or calling, of Pharmaceutical
Chemists shall produce bo the Registrar evidence of having been
previously registered as Chemists and Druggists, and shall be
examined in more extended knowledge of Botany, Materia Medica,
Chemistry, and Physics, or any two of them, which Examination
shall be called the Major Examination.
14. Persons who shall tender themselves to the Examiners for
Examination, under the provisions of the Act 1868, excepting only
those specified in the next following Bye Law, shall be examined in
the Minor Examination.
15. Persons entitled to be registered as Chemists and Druggists
on passing a modified Examination, who shall tender themselves
to the Examiners for examination under the provisions of the Act
1868, shall pass the Modified Examination, which the Council of
the Pharmaceutical Society, with the consent of the Privy Council,
have declared to be in their case sufficient evidence of skill and
competency to conduct the business of a Chemist and Druggist,
as the same is set out in the Schedule hereto, or such other
modified Examination as may in like manner be declared such
sufficient evidence.
Mabch 6, 1897]
PHARMACEUTICAL JOURNAL.
211
Stat.
1852,
sec. viii. ;
Act 1868,
sec. vii.
Stat.
1852,
sec. x. ;
Act 1868,
sec. vii.
Stat.
1852,
sec. x.;
Act 1S68,
sec. vii.
Charter,
line 253.
Charter,
line 253.
Act 1868
sec. vii.
Charter,
line 253.
AH 1868,
sec. vii.
16. All persons desiring registration as Assistants under
the Statute, 1852, or as Chemists and Druggists under the
Act, 1868, excepting those named in the next following
Bye-law, shall pay a fee of Five Guineas if previously regis¬
tered as Apprentices or Students, or otherwise a fee of
Seven Guineas, and pass the Minor Examination, where¬
upon they shall he registered accordingly.
1 7. All persons entitled to be registered as Chemists and
Druggists on passing a modified examination, and desiring
so to be registered, shall pay a fee of One Guinea and pass
the Modified Examination, whereupon they shall be regis¬
tered accordingly.
18. All persons desiring registration as Pharmaceutical
Chemists under the Statute, 1852, shall pay a fee of Three
Guineas if previously registered as Chemists and Druggists
by virtue of having passed the Minor Examination, or
otherwise a fee of Ten Guineas and pass the Major Exami¬
nation, whereupon they shall be registered accordingly.
19. All persons intending to present themselves for
examination in the First Examination shall give to the
Registrar notice in writing of their intention in that behalf
not less than fourteeen clear days prior to the day which
has been appointed for the holding of the said examination.
20. All persons intending to present themselves for
examination in the Major, the Minor, or the Modified
Examination, shall give to the Registrar notice in writing
of their intention in that behalf on or before the fifteenth
day of the month immediately preceding that in which
the Examination is to take place.
i 21. All notices of intention to attend for examination
shall be to attend on the next occttsion of the Examination
being held, and all fees in respect of examination and
registration shall be payable on the giving of notice of
intention to attend for examination, and in no case shall
any fee paid in accordance with the Bye-laws be remitted
or returned.
22. No person shall be admitted to the Major or the Minor
Examination who shall not have attained the full age of
fwenty-one years, nor unless he shall satisfy the Examiners
that for three years he has been registered and employed
as an apprentice or student, or has otherwise for three
years been practically engaged in the translation and
dispensing of prescriptions. Persons who have passed the
Minor Examination at least three months previously may
be admitted to the Minor Examination, and all other
persons desirous of passing the Major Examination may
make application to the Board of Examiners for special
leave in that behalf.
23. Persons who have attended and failed to pass an
examination shall not be entitled to attend on any future
occasion within an interval of three months therefrom,
nor unless and until they shall have given renewed notice
of intention to attend an examination, and shall have paid
fees as follows : —
(a) In respect of a Major Examination, Two Guineas ;
(b) In respect of a Minor Examination, Three Guineas ;
( c) In respect of a First Examination, One Guinea ; —
in cases of renewed notices for examinations to be held before
the expiration of one year, computed from the first day of
the month wherein the Examination was held in respect of
which the original fee was paid. In all other cases fees of
amounts corresponding with the fees paid on the original
notice shall be paid.
16. The Examiners may grant or refuse to such persons as have
tendered themselves for the Minor Examination and the Major
Examination respectively, Certificates of competent skill and
knowledge and qualification ; and lists of such persons shall be
delivered by the Examiners to the Registrar.
17. All persons desiring registration as Chemists and Druggists
shall in respect of an examination, to take place prior to the end
of 1898, pay a fee of Five Guineas, arid shall in respect of an
examination, to take place after 1898, pay a fee of Ten Guineas,
and shall in either case pass the Minor Examination or the Modified
Examination, whereupon they shall be registered accordingly.
18. Persons desiring registration as Pharmaceutical Chemists
under the Statute, 1852, shall pay a fee of Three Guineas and
pass the Major Examination, whereupon they shall be registered
accordingly.
19. Persons intending to present themselves for examination in
the Major, the Minor, or the Modified Examination, shall give to
the Registrar notice in writing of their intention in that behalf on
or before the fifteenth day of the month immediately preceding
that in which the Examination is to take place.
20. All notices of intention to attend for examination shall be to
attend on the next occasion of the Examination being held, and all
fees in respect of examination and registration shall be payable on
the giving of notice of intention to attend for examination, and in
no case shall any fee paid in accordance with the Bye Laws be
remitted or returned.
21. All persons shall, at the time of giving notice of intention to
present themselves for the Minor Examination satisfy the Registrar
that they have attained the full age of twenty-one years, and have
been registered as “ Apprentices or Students,” and that they have
for three years been practically engaged in the translation and
dispensing of prescriptions.
22. Persons who have attended and failed to pass an examina¬
tion shall not be entitled to attend on any future occasion unless
and until they shall have given renewed notice of intention to
attend an examination, and shall have paid fees as follows : —
fa) In respect of a Major Examination, Two Guineas ;
(b) In respect of a Minor Examination, or a Modified Examina¬
tion, Three Guineas ;
(c) In respect of a First Examination, One Guinea ; — •
in cases of renewed notices for examinations to be held before the
expiration of one year, computed from the first day of the month
wherein the Examination was held, in respect of which the original
fee was paid. In all other cases, fees of amounts corresponding
with the fees paid on the original notice shall be paid.
212
PHARMACEUTICAL journal.
[March 6, 1897
PARLIAMENTARY NOTES AND NEWS-
Early Closing Legislation seems as far off as ever. This
session 'has been specially fortunate for private members, who have
had their Tuesdays and Wednesdays untouched by Ministers. Yet
the promoters of the Early Closing Bills have derived no advan¬
tage therefrom. Even the unopposed Half-Holiday Bill of Mr.
Duncombe fails to reach a second reading. Despairing of carrying
his measure through in the orthodox manner, Sir J ohn Lubbock
has given notice that on March 23 he will • call attention to the
excessively long hours of labour in shops, and will move a reso¬
lution in relation thereto.
Calcium Carbide will on April 1 next become subject to the
provisions of the Petroleum Act, 1871, and no person after that
date may keep carbide unless he is licensed in that behalf by
the local authority of his district (see next column). The
“local authority” in the City of London would be the Lord
Mayor and Court of Aldermen, and in Greater London
the London County Council, as the legitimate heritors
of the functions of the Metropolitan Board of Works.
In provincial boroughs, the mayor, aldermen, and burgesses acting
in council are empowered to grant licences, and in places other
than boroughs the local Improvement Commissioners or trustees,
or local board, would become the legal licensing authority. Where
there is no mayor, or commissioners, or board as aforesaid, appli¬
cation for a licence under the Petroleum Act would have to be
made to the justices in petty sessions. In Scotland, places within
the jurisdiction of the Police Commissioners, or bodies acting as
commissioners, are subject to the licensing authority of those
commissioners; places not within such j urisdiction have a “local
authority” in two or more justices of the peace sitting as
judges in the Justice of Peace Court. It is curious to note that
any harbour within the jurisdiction of an harbour authority is, for
the purposes of the Petroleum Act, wholly subject to the harbour
authority, though the place may be part of a borough or may be
within the sphere of a “ local authority.” The licence to keep may
cost anything up to five shillings, and the “authority ” granting the
same may attach such conditions as they may deem fit in the in¬
terest of public safety. It would be as well for chemists and
druggists to consult the Petroleum Act, 1871, which is printed in
the Society’s Calendar for 1897 (2s. of the Secretary).
There will be Difficulties in giving effect to the Order in
Council, owing to inherent defects in the Act of 1871. Local
authorities may be indifferent, or may be sufficiently wise to know
that calcium carbide cannot be treated like inflammable oils, and
they may therefore object to apply the Act. Well, there is no power
to compel them to do so. True, the Board of Trade may make the
regulations in the case of a defaulting harbour authority, but that
would not help matters much. There is some ground for believing,
too, that proceedings under the Summary Jurisdiction Acts not
infrequently result in what is equivalent to fining the prosecuting
body. What authority cares to spend several pounds of the rate¬
payers’ money in prosecuting a person for an offence which the
magistrates may estimate at Is. and costs ?
Mr. Herbert Lewis (Flint Boroughs) is proposing to call the
attention of the Attorney-General to the recent decision by which
the House of Lords upheld the sacred right of an individual to
form himself into a corporate body for the purpose of taking over
his own business. Mr. Lewis no doubt means well, but he must
be of an exceptionally sanguine nature if he expects any very satis¬
factory results to accrue from his appeal to the Government to
check the abuses arising under the present Companies Acts.
Adulteration.— In reply to Mr. Killbride the President of the
Local Goverment Board has announced that the prospects of
introducing a Goverment Bill dealing with adulteration depends
upon the progress of public business. The Goverment Bill would
be a comprehensive one, dealing with the whole question of
adulteration.
Companies Bill. — The Select Committee held its first meeting
on the 1st inst. , and having elected its Chairman, settled various
points of procedure. It is evidently going to perform its duties in
a very leisurely fashion, for the next meeting is three weeks hence,
and it is not proposed to meet much oftener than once in three
weeks. This looks very much like a shelving of the subject for
another Session.
THE SALE OF CALCIUM CARBIDE.
ORDER IN COUNCIL.
At the Court at Windsor, the 26th day of February, 1897.
Present :
The Queen’s Most Excellent Majesty in Council.
Whereas it is provided by the Petroleum Act, 1871, that Her
Majesty may, from time to time, make, revoke, and vary Orders
in Council directing that the said Act or any part thereof shall
apply to any substance, and that the said Act or the part thereof
specified in any such Order shall, during the continuance of the
Order, apply to such substance, and shall be construed and have
effect as if such substance had been included in the definition of
petroleum to which that Act applies, subject to the following
qualifications : — •
1. The quantity of any substance to which this Act is directed
by Order in Council to apply which may be kept without a licence,
shall be such quantity only as is specified in that behalf in such
Order, or if no such quantity is specified, no quantity may be kept
without a licence.
2. The label on the vessel containing such substance shall be
such as may be specified in that behalf in the Order.
And whereas the Petroleum Act, 1879, and the Petroleum
(Hawkers) Act, 1881, are to be construed as one with the Petroleum
Act of 1871, and may, together with such Act, be cited as the
Petroleum Acts, 1871 to 1881.
And whereas carbide of calcium presents dangers similar to
those presented by petroleum.
Now, therefore, in pursuance of the above-mentioned provisions
of the Petroleum Act, 1871, Her Majesty is pleased, by and with
the advice of Her Privy Council, to order and prescribe that the
under-mentioned parts of the Petroleum Acts, 1871 to 1881, shall
apply to the said substance, carbide of calcium, in the same
manner as if the said substance were Petroleum, to which the Acts
apply, viz. : —
The whole of the Petroleum Acts, 1871 to 1881, except : —
(а) So much of Section 6 of the Petroleum Act, 1871, as specifies
the nature of the label to be on the vessel, in lieu of which the
label shall be as hereinafter provided.
(б) So much of Section 7 of the Petroleum Act, 1871, as relates
to the exemption from such Section of small quantities under cer¬
tain specified conditions', and no quantity of carbide of calcium
may be kept except in pursuance of such licence as in the said
Section 7 is provided.
(c) So much of Section 11 of the Petroleum Act, 1871, as relates
to the testing of samples taken by an Officer of the Local Authority
under the powers conferred by such Section.
(d) So much of the Petroleum Act, 1879, as relates to the testing
of Petroleum.
(e) So much of the Petroleum Act, 1881, as relates to the Hawk¬
ing of Petroleum.
The label on the vessel containing the said carbide of calcium
shall bear in conspicuous characters the words ‘ ‘ Carbide of Cal¬
cium : Dangerous if not kept dry,” and with the following
caution : — “ The contents of this package are liable, if brought
into contact with moisture, to give off a highly inflammable gas,”
and with the addition —
(a) In the case of a vessel kept, of the name and address of the
consignee or owner.
(b) In the case of a vessel sent or conveyed, of the name and
address of the sender.
(c) In the case of a vessel sold or exposed for sale, of the name
and address of the vendor. The Order shall come into effect on
April 1, 1897. 0. L. Peel.
Mabcji 6, 1897]
PHARMACEUTICAL JOURNAL.
213
Pharmaceutical Journal.
A Weekly Record of Pharmacy and Allied Sciences.
ESTABLISHED 1841.
Circulating in the United Kingdom, France, Germany,
Austria, Italy, Russia, Switzerland, Canada, the
United States, South America, India,
Australasia, South Africa, etc.
Editorial Office: 17, BLOOMSBURY SQUARE, W.C.
Publishing aqd Advertising Office : 5, SEQLE STREET, W.C.
LONDON: SATURDAY, MARCH 6, 1897.
THE COUNCIL MEETING.
Last Wednesday both the Vice-President and Mr.
Newsholme were prevented from being present at the meet¬
ing of Council by attacks of influenza, and on mentioning
the cause of their absence the President also referred to the
bereavement which has befallen Mr. Johnston, as calling
for the sympathy of his colleagues. The President then
read a letter received from Mrs. Schacht expressing her
appreciation of the kind message sent to her from the
Council. At the same time he showed a photograph of a
portrait of Mr. Schacht from which a replica could be
obtained for a moderate sum, to meet the desire expressed
that such a portrait should be added to the collection now
hanging on the walls of the Council chamber.
The additions to the Society comprised nine Members,
twenty-two Associates and forty-seven Students.
The report and recommendations of the Finance Com¬
mittee were adopted without comment, except by the
President, who pointed out that a legacy of £100 had been
left by the late Mr. Harrv Alma Thomas to the Benevolent
Fund, that the Pharmacy Club had sent a subscription of
twenty guineas, Mr. William Duncan a subscription of
£2 15s. 4 cl., collected at the annual supper of the students
attending classes at the Royal Dispensary, Edinburgh, and
that Mr. Laing had sent £3 collected at a conversazione of
the Glasgow Pharmaceutical Association, all gratifying
indications of the interest taken in the Benevolent Fund.
Mr. Carteighe mentioned that the legacy was left by the
late Mr. Thomas in a will made many years ago, when he
was quite a young man.
On the recommendation of the Benevolent Fund Com¬
mittee, four grants, amounting in all to £32, were ordered
to be paid.
Reference was made to a communication from the Home
Office on the storage of calcium carbide, and the order in
Council therein mentioned will be found on the opposite
page. A memorandum of instructions will be issued by the
department for the guidance of local authorities.
Dr. Si mbs expressed a hope that in regard to any regula¬
tions made for keeping calcium carbide the Council would
exert its influence to secure for chemists such modifications
as were made in the case of benzine.
In connection with the proposed International Pharmaceu¬
tical Congress at Brussels, the President mentioned the
receipt of a letter from the President of the Executive Com¬
mittee, Dr. Fernand Ranwez, and the Secretary General,
M. Duyk, stating that the Congress is to be held in August
next in connection with the fiftieth anniversary of the
General Pharmaceutical Association of Belgium, and expres¬
sing a hope that the Society would take part in the Congress.
A question was raised as to whether the Committee appointed
at Chicago to make arrangements for the next international
congress had been communicated with on the subject, and
Mr. Carteighe, who is a member of that Committee, stated
that he was not aware of any step in that direction, but
thought there might be some little confusion amoDg their
Belgian friends on the point.
A portion of the report of the General Purposes Com¬
mittee was read, stating that the report of the Sub- Commit¬
tee appointed to consider the subject of the Preliminary ex¬
amination had been approved, and was recommended for
adoption by the Council. It recommended that the first ex¬
amination of the Society should be discontinued after June,
1890, and that there should be substituted in lieu of it the
production of certificates of approved examining bodies
covering a wider area of preliminary knowledge. This re¬
commendation provides in a satisfactory manner for the re¬
moval of objections which have long been urged against the
defective character of the Preliminary examination which
has hitherto been the first step towards pharmaceutical
qualification.
Another recommendation was that after 1898 the fee pay¬
able in respect of the qualifying examination should be ten
guineas. This change has been recommended from con¬
sideration of the circumstance that the fee payable on passing
the qualifying examination provides for registration of in¬
dividuals during their life as well as for the actual examina¬
tion, and consequently that the persons benefited by regis¬
tration should contribute to the cost of the work it involves.
Both these recommendations will probably meet with very
hearty approval, as being calculated to promote the best
interests of registered chemists as educated members of a
body in whom the public can have confidence. The remarks
of the several members of Council who spoke in reference
to these recommendations did not in any way partake of the
nature of a discussion, but rather indicated a perfect
unanimity of opinion as to the desirability of the changes
recommended (see p. 207). In accordance with that general
agreement, the draft of necessary modifications in the Society’s
bye-laws, submitted by the sub-Committee, wras read a first
time, and the other recommendations were adopted.
BENEVOLENT FUND SPECIAL APPEAL.
The Secretary of the Manchester District Committee de¬
sires us to say that a further list of donations to the Benevolent
Fund, promised as a result of the special appeal, particulars of
which appeared with a preliminary list in last week’s
Journal (p. 180), will be published next week. We are
glad to learn, also, that a meeting of assistants and appren¬
tices is to be held in Manchester, on Wednesday evening
next, for the purpose of forming a committee to further the
214
PHARMACEUTICAL JOURNAL.
[Mabch 6. 1897
same object. Lists have not yet been received from Glasgow
and Liverpool, though we hope to be able to announce the
arrival of such in an early issue. Meanwhile we shall be glad
to notify extra subscriptions and donations from individuals
in any other districts than those mentioned.
THE TEACHING OF BOTANY.
An Institute for Teaching Botany, on the lines suggested
by Mr. William Martindalk (see p. 203), should prove of
national importance to the people of the greatest colonising
country the world has ever seen. Lor though the Royal
Gardens at Kew can supply scientific and technical informa¬
tion of the kind required by colonists and travellers to a
practically unlimited extent, no means are provided there for
systematic instruction in botany, even on the purely economic
side. Experts may find at Kew everything they require to
facilitate research in botanical subjects and their work be bene¬
fited accordingly, but ordinary students in any branch of the
science are not at home there, and find it difficult to assimi¬
late even a limited quantity of the good things provided.
Moreover, it is difficult to see how more direct educational
facilities could be provided at the Royal Gardens, such a
development being quite outside their scope.
But the Royal Botanic Gardens accomplish much from
a directly educational point of view, some seven hundred
students making use of the facilities they offer, whilst
nearly sixty thousand specimens from living plants are dis¬
tributed to students and teachers annually, and already the
Royal Botanic Society’s Gardens serve as the source of
specimens for the numerous teaching bodies in London. But
there seems a sufficient opening for a new teaching institute
in connection with the Gardens, which need not in any way
trespass on ground that is now efficiently covered by exist¬
ing teaching bodies. Lor, if the work of tuition can be
performed on the spot better than in places some distance
removed from the Gardens, there seems to be no sufficient
reason why even elementary botany should not be taught
there, as it must be preferable to study the subject practically
in the midst of suitable living material, rather than to cram
it in college class rooms or from books alone.
On the economic and technical side, however, the chief
value of the projected scheme seems to lie. Lor though study
and research in vegetable physiology, anatomy, histology
and pathology are essential, yet they are already more or less
suitably provided for elsewhere. On the other hand, in this
country, it is not easy to gain instruction respecting the
diseases of plants, the value of timbers, the preparation of
vegetablefibres, and the collection of indiarubber, gutta-percha,
gums, resins, and drugs. Nor do the needs of agriculturists
and arboriculturists receive anything like the amount of atten¬
tion they deserve. Everything, therefore, seems to favour
the idea that a British institute for the teaching of botany,
if properly established and equipped, should prove a great
success, and there can be little doubt that it ought to be
situated in or near London, whilst of the limited number of
places that might be available for the desired purpose, the
Royal Botanic Society’s Gardens appear to possess
exceptional advantages. Much will require to be done, of
course, before the project can be regarded as even fairly
on the way to realisation, but there seems to be sufficient
force behind the movement to go far towards overcoming
all initial difficulties. Mr. Martindalk, in particular, appears
to be very much in earnest about the matter, and when he
takes a thing in hand he is not apt to let it languish.
ANNOTATIONS.
The Annual Meeting of the Pharmaceutical Society, which
is this year to be held on Wednesday, May 19, will be the fifty-
sixth occasion of the Council meeting the Members to discuss the
previous year’s work and its results, and the fifty-fifth similar
meeting held at No. 17, Bloomsbury Square. As the decennial
dinner on behalf of the Benevolent Fund will be held at the Hotel
Cecil on the previous day, it may be anticipated that the annual
meeting will be much more largely attended than usual, especially
in view of the important changes effected and proposed by the
present Council during its year of office.
Evening Meetings of the Pharmaceutical Society will be held
both at London and Edinburgh next week, this being rather an
unusual occurrence. At Bloomsbury Square, on Tuesday, Mr.
John C. Umney will read a paper on “ The Commercial Varieties
of Fennel and their Essential Oils,” and it will be interesting to
know whether he has found any such difference in the oils as he
has already shown to exist in those extracted from English and
Indian dill fruits. A paper will also be read by Mr. William
Martindale on “The Preservatives of Pharmacopceial Preparations.”
At this meeting the chair will be taken by the President, Mr.
Walter Hills, at the usual time, eight o’clock.
The Edinburgh Meeting .will be presided over by Mr. J. Laid-
law Ewing, the popular Chairman of the Executive of the North
British Branch. A paper on “Essence of Ginger” will be read
by Mr. W. S. Glass, and a “ Note on a Sample of Scammony,” by
Mr. T. W. Thomson. Recent additions to the Museum and
Library will be exhibited and referred to by the Assistant-Secre¬
tary, Mr. J. Rutherford Hill, as far as time may permit. The time
of assembly in this case is nine o’clock, an hour later than in
the case of the London meeting.
If the Pharmaceutical Society could do all that writers in
daily newspapers credit it with power to do, there would be slight
reason to trouble about the few things it could not do. But all-
powerful though the Society may appear to uninformed pressmen,
it does not yet take precedence of Health Committees in suppres¬
sing public nuisances other than the illegal sale of poison. The
necessity of this disclaimer is caused by the comments of a writer
in the Birmingham Daily Mail, who seems to have a curiously
exaggerated idea of the extent to which the Pharmaceutical Society
can interfere with the retailing of medicaments.
Small Shopkeepers in the Huckster Line, he correctly
observes, cannot be prevented from doctoring the poorer classes
with cheap pills, as even the Birmingham Health Committee has
no power to interpose unless the medicine is not of the substance
and nature demanded. “ This is where the difficulty comes in,”
he continues. “ The manufacturers of these cheap pills make no
pretence as to their quality. They are credited with possessing
great curative powers, and, in short, are said to cope with every
affliction, from corns to broken legs.” Unfortunately, in this
country exceptional latitude is given to the vendors of quack
medicines, whereas on the Continent none but a properly qualified
medical man is allowed to prescribe for a patient. But in England
the small huckster is permitted to thrust on ignorant people any
of the cheap and nasty nostrums he may be vending, and it is
difficult to see on what ground the Pharmaceutical Society
can be expected to interfere, aS suggested, or how it should
take the matter in hand and prevent further mischief. The
persons who can best prevent, mischief in this direction are the
March 6, 1897]
PHARMACEUTICAL JOURNAL.
215
people who encourage the sale of quack remedies by purchasing
and using them. Until such persons are content to abstain from
doctoring themselves it is quite hopeless to endeavour to stem the
flood of rubbishy and often injurious physic.
The Students’ Page shares the fate of much other interesting
matter this week, in being displaced by the extra numerous and
lengthy reports of different societies and associations, although
the present number contains four extra pages. But oppor¬
tunity will thus be afforded for the more perfect digestion of the
large supply of excellent mental pabulum provided for our student
readers last week. It ought hardly to be necessary at the present
day to devote so much space in a weekly publication to such infor¬
mation as we are now providing for students, and especially
junior students, but there is little doubt that text-books for
pharmaceutical students are remarkably lacking at the present
time in the matter of details that are not generally available. In
connection with almost every department of knowledge having a
direct bearing on pharmacy, there seems to be room for a good
practical text-book. Failing the production of such aids, how'
ever, and in the hope of inducing young students to acquire a
more thorough knowledge of the principles upon which pharmacy
is based, space will be found in the Journal for what is required,
as frequently and regularly as circumstances will permit.
The Notes on Practical Pharmacography undoubtedly fill an
important gap, and already the complimentary references made
in relation thereto have been many. The idea upon which the
notes are based is that of supplementing existing text-books, and
as far as possible bringing the subject up to the level of present-
day knowledge. To this end the best sources of information
accessible are being freely drawn upon, and the work of Holmes,
Squire, Vogl, Moeller, Tschirch, Oesterle, Planchon, Collins and
others utilised as far as possible. It would obviously
be impracticable to quote authorities for every statement that is
made, but the utmost care is being taken to accept nothing except
upon good authority, and to verify the statements made as far as
possible. Not least among the advantages offered by this series
will be the gradual completion of what may fairly be regarded as
a pharmacographic atlas, such as has long been a desideratum in
this country. Germany and France are well supplied with such
atlases, but enterprise has been lacking to furnish British pharma¬
cists with similar aids. The illustrations of drugs are prepared by
a skilled artist under careful supervision by an acknowledged
authority in organic materia medica, and the histological drawings
are reproductions of those by leading pharmacognosists.
The Students’ Dinner held last week should prove an excel¬
lent advertisement to the School of Pharmacy. It was the first
occasion on which a School Dinner, properly so called, had been
held, and as such was a great success, one of the most striking
things in connection with it being the representative character of
the assembly. The students of to-day, of course, turned up in force,
together with the whole of the School Staff, but there werealso present
honoured representatives of the students of the earliest days, and
of the older teachers, in addition to members of prominent
city firms and many of the officials of the Pharmaceutical
Society. Excellent speeches were delivered by several of the
students, giving promise of fine oratorical displays in the not far
distant future. On the whole the change, by which the annual
dinner has come to be that of the School of Pharmacy rather than
of the Pharmaceutical Football Club only, must be described as
not the least attractive of those that have taken place during the
past twelve months.
The Bristol Pharmaceutical Association is desirous of culti¬
vating the social side of pharmacy, and to that end intends to hold
a dinner on Wednesday, March 10. The tastefully got -up circular
announcing that event has been sent, it is believed, to every
chemist in Bath, Clevedon, and Weston-super-Mare, as well as
Bristol, but in case anyone has been inadvertently overlooked, the
Honorary Secretary, Mr. B. Keen, wishes it to be understood that
all members of the craft will be welcome. Tickets (4s. 6d. each)
may be obtained on application to him at 90, Park Street, Bristol.
Death of Mr. Arthur Tyrer. — The deepest regret will be felt
by all friends of Mr. Thomas Tyrer at the unspeakably sad acci¬
dent which has resulted in the loss of his second son at the early
age of twenty years. Mr. Arthur Tyrer was studying at Marburg,
and had been engaged in an investigation of Chelidonium majus,
which is now attracting some attention on account of its medi¬
cinal properties. The result of this research was to have formed
the subject of his “arbeit” or thesis, which would have been
presented on taking his degree. A few days ago, howeimr,
whilst swimming in the river Lahn with some fellow students,
he suddenly called out that he had the cramp, and before
assistance could reach him he sank and was drowned. The river
is, of course, much swollen at this time of the year, and the body
had not been recovered when the latest intelligence arrived. The
deceased was a very promising student, and great hopes were
centred in him by his father, who now finds them dashed in a
manner that must render him the object of universal sympathy in
pharmaceutical and chemical circles.
Dispenserships in the Naval Medical Service are now, we
understand, to be open to persons holding the licence of the
Pharmaceutical Society of Ireland to act as pharmaceutical
chemists. The decision cannot, however, be carried into effect
until an Order in Council has authorised the change. We are
given to understand that appointments under the new regulations
will be made by open competition, and that such competitions will
be conducted by the Civil Service Commissioners.
The Proprietary Articles Association is already supported
by many grocers, and is now extending its sphere of operations to
dealers in photographic materials. At the instigation of the
Photographic Dealer, a meeting attended by prominent members
of the trade was held at Anderton’s Hotel, Fleet Street, E.C., on
Wednesday afternoon last, and it was then decided to take steps
to form a photographic branch of the P. A. T. A. For some time
past Messrs. R. and J. Beck, Limited, and the Thornton-Pickard
Manufacturing Company have done their best to prevent cutting ;
and more recently Messrs. W. Butcher and Son have followed
their example in striving to maintain retail prices. Apparently,
the makers of medicines, druggists’ sundries, etc., are not the only
ones who are feeling the reaction due to the reduction of retailers’
profits.
The Postmaster-General is to have an opportunity of proving
the legality or otherwise of demanding return postage on un¬
delivered newspapers when returned to the senders, the Strand
Newspaper Company having decided to fight the matter as one of
principle. This is only one of the numerous ways in which news¬
paper proprietors are continually being unnecessarily worried by
the postal authorities, who are apt to pose too much as dictators.
216
PHARMACEUTICAL JOURNAL.
[Maech 6, 1897
LITERARY NOTES.
The * Proceedings oe the Chemists’ Assistants’ Association ’
for 1895-96 is just published, and contains the papers and discus¬
sions of the past session, together with full particulars of all the
meetings, lists of members, patrons, officers, etc. The hundred
pages thus occupied show what a power for the improvement of
pharmacy the Association continues to be, and that it yet remains
as vigorous as ever. Moreover, it is in a healthy financial position,
and thus well able to afford the luxury of furnishing its members
with a complete record of the year’s work. It is published by the
Association at half-a-crown.
Squibb’s ‘ Epiiemeris ’ appears so rarely nowadays that one is
apt to forget its existence and overlook the useful part it has
played in the past. The issue for January, 1897, serves therefore
as a useful reminder on both points. More than 250 pages are
devoted to recent developments in materia medica, pharmacy,
therapeutics, and collateral information, the monographs being
arranged in alphabetical order so that reference is greatly
facilitated. Even the Rontgen rays find a place here, in a
well-illustrated article, and every one who may be privileged to
receive a copy of the work should find it of great value. It is
published by the Messrs. Squibb, at Brooklyn, New York.
Von Sudthausen’s ‘ Guide for the Use of Doctors and Apothe¬
caries ’ is a capital pronouncing dictionary of medical and phar¬
maceutical terms. There are two volumes — English-German and
German -English — and all the terms are conveniently classified.
The English equivalents halt occasionally, but not to the extent
of rendering them unintelligible, though they are somewhat
amusing at times, and those who may have occasion to dispense
German prescriptions or read German medical and pharmaceutical
books and papers will find the work of considerable use. It is
published by Eduard Besold, of Leipsic, at five shillings.
‘ Knowledge ’ for March opens with an attractive illustrated
account of Nansen’s voyage, and altogether offers a rare treat to
naturalists, amongst the other contributions being articles on the
Victorian Era in geography, the origin of some domestic animals,
the vegetation of Australia, the chemistry of the stars, and the
life-history of the common tiger beetle. The names of the writers
are those of experts in their respective subjects, and a cheaper
record of current science— popular and yet exact — would be
difficult to find.
‘ Natural Science ’ is more advanced in style, but equally
interesting in its subject matter. In the March number, Dr.
Alfred Russel Wallace treats of ‘ ‘ The Problem of Instinct ” ; Pro¬
fessor Anton Fritsch of “ Fresh- water Biological Stations”; and
H. M. Bernard of “The Light-Sensations of Eyeless Animals”;
whilst various writers deal with the topic* of “ Human Evolution.”
‘ Science Gossip ’ seems to have settled down fairly after its many
vicissitudes, and comes out fresher than ever, month by month.
The inevitable Nansen article appears on the first page of the
March issue, and a rare feast is afforded for all lovers of Nature
in the varied communications on biological subjects.
MEETINGS Of SCIENTIFIC SOCIETIES
- ♦ -
Linnean Society of London, Thursday, February 18. —
Dr. D. H. Scott, F.R.S. , Vice-President, in the chair. — Sir
William Roberts, Mr. J. M. Lowson, and Mr. W. H. Betts were
admitted, and the Hon. Charles Ellis and Mr. G. E. Lodge were
elected Fellows of the Society.
A Wren’s Nest in a Rook’s Body.
Mr. J. E. Harting exhibited under a glass case the nest of a wren
built of moss in the dried body of a rook which had been hung up
as a scare-crow in Gloucestershire. Similar instances of the kind
had been recorded (‘ Essex Nat.,’ ii., 205, and iii. , 25). He called to
mind the nest of a swallow in the dead body of an owl mentioned
by Gilbert White, and referred to other cases which had been
collected by a former president of the Society (Bishop Stanley,
‘ Hist. Birds’). For instances of nests of the hoopoe placed in the
desiccated bodies of unburied men he referred to the experience
of Pallas in Russia and of Swinhoe in China.
Morphology and Anatomy of some Nymph.eace^e.
On behalf of Mr. D. T. Gwynne Vaughan, Dr. D. H. Scott
gave the substance of a paper on the Morphology and Anatomy of
certain Nymphceacece. Dealing first with the embryonic leaves, he
showed, by the aid of lantern-slides, a series of transitional forms
between the earliest leaf, which is acicular, and those of the mature
plant. As regards the vascular system, the whole central region of
the rhizome in Victoria regia was shown to be permeated by a number
of separate bundles irregularly anastomosing ; the more peripheral
bundles appearing to be arranged in a definite manner, forming a
limiting zone, the outermost phloem-strands of which do not run in
a vertical but in an obliquely horizontal direction. In Nymphcea and
other genera, the vascular system is not limited by such a peripheral
zone. Nothing corresponding to a plerome could be distinguished in
the apex of the mature rhizome of Nymphcea or of the floating
shoots of Cabomba aquatica. In those species of Victoria, Nymphcea,
and Nuphar which were examined, and also in Cabomba aquatica
and Ndumhium speciosum, the adventitious roots do not arise in¬
discriminately upon the vascular bundles scattered in the ground-
tissue of the rhizome, but are borne upon some which appear to
be specially set apart for that purpose, and form a structure es¬
sentially similar to a stele, which reaches the greatest perfection in
Victoria regia. In species of Nymphcea which produce many roots
at each leaf -base the root-bearing stele is perfectly constituted, but
in others, and in Nuphar, the vascular bundles are few in number,
and are not arranged with sufficient regularity to constitute a
stele, although they bear exclusively the adventitious roots. In
Nelumbium speciosum the seedling was shown to be remarkable on
account of the complete abortion of the primary root, and also on
account of the complexity exhibited by the vascular system in the
earliest or epicotyledonary internode. The rhizomes of Nymphcea
Jlava and N. tuberosa bear a number of small tubers on stalks, or
stolons, of varying length, 'wherein the vascular system exhibits a
polystelic arrangement, the bundles being grouped around three
to five different centres to form so many steles, consisting of three
or four bundles each. When the tubers which are borne at the
ends of these primary stolons germinate, they give rise to a number
of narrow secondary stolons, which in turn produce new rhizomes
at their extremities.
The Adhesive Discs of Ercilla Spicata.
Mr. J. H. Burrage read a paper on the adhesive discs of Ercilla
spicata, Moq. He showed, with the aid of lantern-slides, that the
adhesive organs were developed endogenously immediately above
the axils of the leaves, and that each was made up of a mass of
parenchyma with a central plate of tracheids in connection with
the bundles of the stem at the base of the disc. It appeared also
that hairs which force their way into the crevices of the support
are formed from a special layer of columnar cells beneath the
epidermis, resulting in the exfoliation of the latter. After a time
the walls of the cells in the external layers of the discs become
suberized, a periderm being eventually formed from a definite
cambium just outside the vascular plate. It was further shown
that while absolute contact was necessary for complete develop¬
ment, discs of various sizes might occur some distance
from the support, possibly stimulated to growth by a moist
environment. It was found that a few discs gave rise to small
March 6, 1897]
PHARMACEUTICAL JOURNAL
217
roots, and as the walls of the cortical cells were invariably suberized’
they could not act in a normal manner. While there was no
evidence to show that they were anything but climbing organs, a
comparison with parasite suckers, such as those of Guscuta,
suggested the possibility that the discs were not far removed from
acting parasitically.
Royal Botanic Society, Saturday, February 27. — Mr.
Birkett in the chair. — A large number of Fellows and visitors
were present at this meeting to hear a paper read by Mr.
William Martindale on the advisability of founding an
Institute in connection with the Royal Botanic Society for the
purpose of teaching systematic botany (see page 203). — The Chair¬
man, when calling upon Mr. Martindale to read his paper,
expressed the opinion that if the scheme could possibly be carried
out it would redound much to the honour of the Society. At the
conclusion of the paper Mr. Birkett spoke very favourably of the
scheme brought forward by Mr. Martindale. The subject, he said,
was one of very great interest, and one which might possibly be
carried out if Fellows of the Society and other gentlemen interested
in botany would take it up warmly, but it was one of those things
which require three or four strong-minded people to work at
heart and soul, as it cannot be carried through without.
He had great pleasure in proposing a vote of thanks
to Mr. Martindale for the excellent way in which he had
brought the subject before them. — Mr. Pembroke Stephens, Q.C.,
referring to the fact that there were present in the room a number
of eminent scientists practically interested in the matter, said the
subject was one which for some time had been under the considera¬
tion of the Society, but it had been through the energy and pains
which Mr. Martindale had put to it that it had been brought into
practical shape. The Council would now be very glad to launch
the idea, and to be assisted by the views and advice of those who
are interested. If some step could be taken of a practical nature
to collect opinions and to obtain information, it would be a very
desirable outcome of that day’s proceedings. The Council would
therefore be glad to hear the views of anyone interested in the
subject. — Dr. Scott, of Kew, thought the scheme which Mr. Mar¬
tindale had sketched was one which would at once command the
sympathies of botanists generally. He considered that at present
there was great need in London for a botanical institute.
With regard to the question of teaching, he was of opinion that
there could be no doubt whatever as to the great desirability of
botanical teaching being conducted where original research may
be carried out on the spot, and no place was more suitable for the
purpose than the Gardens of the Society. Teachers of botany in
London constantly felt very painfully the want of a garden in
which to give practical instruction to the students. While his
entire sympathy was with the plan, which he believed would be of
the greatest possible advantage if the teaching take a practical
direction, Dr. Scott thought that in establishing such an institu¬
tion great care would have to be exercised so as not to enter
into any undesirable competition with the existing institutions. —
Professor Oliver, University College, re-echoed very heartily the
opinions expressed by Dr. Scott. He believed that botanists, not
only those in the Metropolis, but others in university towns,
would hear with great pleasure of the progressive movement pro¬
posed by Mr. Martindale. He thought that botanists generally
would willingly assist the scheme, not only in a platonic manner,
but by active operations, and would be glad to form themselves into
an unofficial committee to, if so desired, confer with the Society on
any practical suggestions. — Mr. G. W. Bell thought Professor
Oliver’s suggestion to form an unofficial committee for the purpose
of carrying out the scheme to be a very good one. — Professor
Henslow, of St. Bartholomew’s Hospital, agreed with all that had
been said by Mr. Martindale and the other speakers as to the
usefulness of a botanic institute, but to establish such an
institution would involve the expenditure of a great amount of
money, and he questioned whether a sufficient number of students
could be found to employ the necessary staff of teachers.
Botanists of the old days were mostly medical men, but from
what he knew of the present medical students they would
learn exactly what they were obliged to learn and not one
item more, and he did not believe they would take advantage
of a botanic institute. He doubted whether they would
et many lady students even, except, possibly, a few teachers,
ut apart from that, there would be the question as to how the
overlapping of other existing institutions could be got over. —
Mr. E. M. Holmes, Curator of the Pharmaceutical Society’s
Museums, did not believe there would be any great difficulty in
procuring students, he was of opinion that many men who were
thinking of going abroad as agriculturists would gladly take
a course of training in practical botany before leaving England.
Commercial men too, he knew, would be very glad in many cases
to send their young pupils to an institute where they could gain a
practical knowledge of the plants used in their particular business.
From the number of applications he was continually receiving for
botanical information he felt quite sure there was a good opening
for teaching of that sort. He thought it would be a great pity if
the Council could not see their way to establish an institute. — Pro¬
fessor Greenish, of the Pharmaceutical Society, added his testi¬
mony to that of Mr. Martindale and others who had spoken in
favour of the scheme. Both from a teacher’s point of view,
and also as an old student, he was strongly of opinion that
it was highly desirable for a botanical institute to be situated
where suitable material can readily be obtained for the pur¬
poses of instruction. — Professor Sydney Ringer did not agree
with Professor Henslow in thinking that students will only
take just a sufficient amount of trouble in order to acquire the
necessary knowledge to pass the examinations and no more. He
thought if the Gardens of the Botanic Society were better developed
students would come. As a practical man, he advised the
Council to begin carefully the work of establishing a bettef system
of teaching botany in the Gardens and to gradually extend their
operations. — Mr. M. Carteigiie, after remarking that what botany
he knew was acquired in the Society’s Gardens and Museum, re¬
ferred to the large number of petty institutions in London where
botany is supposed to be taught, and said he thought if the Council
could establish an institute for the teaching of practical botany it
would probably absorb all the feeble teaching he had mentioned.
Had he been asked twenty years ago if there was room for such an
institution he would have said “ No,” but biology of itself is an
intellectual work that commends itself to the nation, and there is
an interest growing up amongst the public at large in the
subject, and apart from that, the training involved in the
research itself is second to none in fascination, and at
the same time of benefit to mankind. On the ground of original
research in this particular subject, an endeavour should be made
to establish a technicum, and if men were put in who were capable
of making original research, he believed they would attract a large
number of pupils ; but whether they did or whether they did not,
if they were able to turn out good work only, he was of opinion
the public at large would support it. People were beginning to find
that there is a great deal of good in knowing about botany. Mr.
Carteighe thought it a disgrace that in London there should be
no means of obtaining that particular kind of knowledge which
is capable of being obtained at the Botanic Gardens, and
if the Council went boldly to the public with a workable scheme
they would be supported. — Mr. Rubinstein, Professor Farmer,
and Dr. Boxall also spoke favourably of Mr. Martindale’s scheme,
reference being made to the progress Germany had made in this
direction. — The Chairman then announced that the matter would
be adjourned to be considered by the Council, and stated that if
any gentlemen interested in the subject would like to be appointed
on the committee to work the scheme, they would be glad to
receive their names.
Royal Institution, Monday, March 1.— Sir James Crichton-
Browne, M.D., F.R.S., Treasurer and Vice-President, in the chair.
— At the General Monthly Meeting the following were elected
Members: — Mr. F. J. Beaumont, Major C. T. Blewitt, R.A., Mr.
J. F. L. Brunner, Mr. James Cadett, Mr. J. C. Carter, Mr. John
Cohen, Mrs. Thomas Collier, Mr. J. G. Craggs, Mr. T. Donaldson,
Mr. Henry Edmunds, Mrs. Henry Edmunds, Mr. G. S. Elliot,
Mr. W. A. Frost, F.R.C.S., Mr. W. T. Garnett, J.P., Mr.lH. A.
Harben, Dr. F. Hewitt, Mr. F. W. Hildyard, Mrs. George King,
Mr. H. Leitner, the Rev. J. D. Parker, Mr. E. M. Preston, Mr.
J. M. Richards, Colonel G. Sartorius, Mr. F. H. Schwann, Dr.
W. R. Smith, Mr. H. A. Stern, Mr. C. J. Stewart, Mr. G. L.
Stewart, Mrs. A. D. Waller, and Mrs. J. Lawson Walton.
Peronine, a New Morphine Derivative. — Merck has intro¬
duced the chlorhydrate of the benzylic ester of morphine, under
the name of peronine, as a substitute for codeine. In therapeutic
action it ranks between morphine and codeine, and is specially
serviceable in the spasmodic cough of phthisis. The dose is from
two to four centigrammes in pills or in tea, — Bull. Commerc.}
xxv., 38.
218
PHARMACEUTICAL JOURNAL.
[March 6, 1897
THE WORLD OF PHARMACY.
- ♦ - -
BUSINESS MEETINGS.
Chemists’ Assistants’ Association, Thursday, February 25.
—Mr. C. Morley, President, in the chair. — Mr. E. H. Farr read a
paper entitled — •
Notes on Some of the Pharmacopceial Processes for the
Determination of Alkaloids,
by E. H. Farr, F.C.S., and R. Wright, F.C.S. (see p. 202). At the
conclusion of the paper the President opened the discussion by re¬
marking that this was a very opportune time for bringing the
subject of the present notes forward in view of the forthcoming revi¬
sion of theB.P. — Mr. F. C. J. Bird said that the authors were well
qualified from their long experience to treat on the subject of alka-
loidal assay. When assay processes were first introduced they
rendered great service in showing defects, but that certain pre¬
parations, like those of nux vomica, for instance, though made
from standard extracts, might yet be of different strengths. Then,
too, a sample of opium might be assayed by the B.P. process
and yield one result, but when a different process was
followed, and “any trustworthy method” was permissible, quite
a different result might be obtained. He considered the use
of morphinated water a very great improvement. He had tried
Messrs. Farr and W right’s published process on several occasions
in comparison with that of Teschemacher and Smith and obtained
very concordant results. He wished to know whether Messrs.
Farr and Wright had had any experience with Fliickiger’s process.
— Mr. Robinson inquired whether the presence of a small propor¬
tion of glycerin in an extract of opium would interfere with its
assay.— Mr. Moore was glad to see that titration of the morphine
was advocated, as he considered it very necessary to do so. He
had experienced the advantage of using flat-bottomed
dishes for drying extractives, etc., and some time since
had tried to get some nickel dishes of that shape
from an apparatus firm. They stated that they had often
had inquiries for them, but that the makers were in the habit
of making them round, and did not seem disposed to make them
of any other shape. — Mr. Guver inquired whether Mr. Farr
had ever tried aluminium dishes, because they could be had with
flat bottoms. — In reply, Mr. Farr said that with reference to Mr.
Bird’s remarks as to difference of strength, of course the other alka¬
loids present in opium and the brucine in the nux vomica had their
physiological effect, and two standardised preparations of either
opium or nux vomica might not have the same physiological
effect, owing to the variable proportions of those alkaloids present.
With reference to Fliickiger’s process, they had tried it on three of
the samples, and the results afforded by it were much lower than by
the other three. Samples A, B, and C were the samples in question,
and proportion of morphine indicated was as follows : A, '762 ;
B, ‘787 ; C, '870. The presence of a small proportion of glycerin
was of no importance in the assay of opium preparations, as
morphine was not very soluble in it.
Plymouth, Devonport, Stonehouse and District
Chemists’ Association (Junior Section), Wednesday, Feb¬
ruary 24. — Mr. Geo. Breeze, J.P., President, in the chair.— A
lecture was given in the Plymouth Technical School by Dr. W.
Cheyne Wilson on the
Rontgen Rays.
There was a splendid attendance numbering about 130, including
about forty ladies. Amongst those present were Messrs. C. J.
Park, J. Cocks, J. Burns Brown, B.A., B.Sc. ; Cantle, E. A.
Hodge, J. A. Buckley, A. D. Breeze, F. W. Hunt, C. T. Weary,
J. Harvey Bailey, J. R. Johnson, H. D. Davey, etc. After showing
electrical experiments which led up to the discovery by Professor
Rontgen, the lecturer placed about sixty photographs on the screen
illustrating the surgical and medical use of the rays, which have
been tried, though as yet unsuccessfully in cases of consumption
and cancer. Knowing that the bacillus of the former are killed by
heat, it was thought that by applying the rays for a short time
each day to the patient’s chest they would kill the bacteria, but up
to the present no success has been obtained. In cancer the few
cases that have been tried have been relieved for a short time by
reducing the swelling, thus allowing the patient to breathe more
freely, but each case has proved fatal. What the so-called X rays
really are has not yet been ascertained, but Dr. Wilson expressed
the opinion that they are modifications of light or vibrations of
ether, moving so rapidly that they are not visible to the naked eye,
though they can be demonstrated by special means.
Brighton Junior Association of Pharmacy, Wednes¬
day, February 24. — Mr. C. G. Yates in the chair. — A debate took
place on the
Proprietary Articles Trade Association,
being opened by Mr. W. Howes, who moved the following resolu¬
tion : —
“That this Association approves and wishes to support the objects of the
Proprietary Articles Trade Association.”
In the course of his remarks Mr. Howes said he quite agreed with
the movement, and wished it every success, and thought that it
would prove a great benefit to chemists, but at the same time he
was afraid that the advantage would not be permanent, as the
P.A.T.A. was bound to fail ultimately by reason of the middle¬
man. By this he meant that a man could buy a large quantity
of the protected articles at the minimum wholesale price and
supply them to retailers at a fraction above that price without
their signing the usual agreement, and that, therefore, they
could sell them below the minimum retail price fixed under
the P.A.T.A. rules, and he was afraid, therefore, that this
would prove the cause of the failure of the whole scheme.
Chemists should refuse to stock any preparation which did not
bear an adequate profit, and in the case of the majority of
proprietary articles the profit is certainly not sufficient. — Mr.
A. T. Jeeves thought the P.A.T.A. a useless and superfluous
organisation, organised by manufacturers and owners of proprietary
medicines, etc. , to suit their own ends, to put a trifle better profit on
the articles in order to tempt the chemist to push the sale of them
instead of his own preparations. With regaid to the agreements
not to sell below the stated minimum prices, he considered that
they were useless. — Mr. Feltwell spoke in support of the motion,
and said the remarks of the introducer in regard to middlemen
would not stand at all. The plan would not work, as supplies
would be refused a second time. But even if the P.A.T.A. fails in
its primary object, it would have done an enormous amount of
good work in causing chemists to combine, and it should be sup¬
ported on that account. Messrs. A. H. Cubit, C. A. Blamey, and
C. G. Yates also spoke, the last mentioned observing that it was
quite natural for everyone to feel that they would like to do as they
pleased as regarded the prices at which they sold goods, but should
we not rather, to further our own interests and those of the trade
in general, make one in a combination to effect the desired end ?
One of the great results of the work of the P.A.T.A. was the com¬
bination of the trade, and several new chemists’ associations have
been formed in consequence of it. — The motion was then put to
the meeting and carried by a very large majority.
Edinburgh Chemists’, Assistants’, and Apprentices’
Association, Friday, February 26. — Mr. J. McBain, President,
in the chair. — The first paper read was by Mr. Alexander Suther¬
land o*n —
Accuracy.
The author said we who live in “the foremost files of time”
were “the heirs of all the ages.” Yet it was common to
brand much of the work and record of the past as inaccurate,
and to scoff at our heritage. His purpose was to sug¬
gest that all should so study accuracy in adding their
portion of work to the total of the past that their heirs might find
no inaccuracy therein. He gave several examples of how large
numbers of people might be wholly misled by even a small in¬
accuracy of statement, and how a single inaccuracy might shake a
reader’s confidence in the whole of what was otherwise a true
record of really good work. In recording original work there
were three different ways in which there must be accuracy: —
First, there must be accuracy in preliminary knowledge.
They must have a thorough grasp of the elementary
principles involved in the work in hand ; without this accurate
work was impossible. Secondly, there must be accuracy
in their methods and manipulat on. This was illustrated by
reference to the question of percentage solutions. Thirdly they
must be studiously accurate in the interpretation and recording o
March 6, 1897]
PHARMACEUTICAL JOURNAL.
219
results. Then if somebody read the record and said that X did
that a hundred years ago, and Y did that a thousand years ago,
if their work was accurately done, they would have all the glory,
and would not trouble themselves a bit about being anticipated
by X and Y. Quite a lot of their modern ideas and of their modern
work was “ made on the Continent” ages ago, and the only credit
they could have was that they had taken the ideas and tried to
make them accurate.
The next paper was by Mr. George Lunar, on
The Specific Gravities of the B.P. Preparations.
The author, in an exhaustive and elaborate paper, explained the
theory on which the method of determining specific gravities is
based, and the precautions to be observed in the manipulations and
deductions so as to ensure accuracy. He pointed out that with
three exceptions condensation took place in preparing all the dilute
acids, liquors, and spirits of the Pharmacopoeia. The exceptions
were liquor ferri acetatis and spiritus chloroformi, in which cases
no change of volume occurred, and liquor ammonia where there
was an actual expansion of 0 "46 per cent. He suggested that this
ready and useful physical method of determining purity might be
greatly extended to liquids as well as solids, and it was to be
expected that this would be done in the forthcoming Pharmacopoeia.
Aberdeen Junior Chemists’ Association, Friday,
February 26. — This being “Magazine Evening,” the following three
papers were read by the Editor, Mr. Douglas : — (1) “ Suggestions
for the Future.” This paper set forth some good suggestions for
the benefit of the Committee and Association of next session. (2)
“ Tobacco Smoking.” The writer treated both sides, for and
against smoking ; showing its ills and merits. (3) “ Suggestions
for Increasing the Popularity of the Association.” The writer
gave a brief account of the very successful session now almost
closed, at the same time pointing out some new methods of working
the Association, and the adoption of his suggestions would add
much to the Association’s attraction for the embryo chemists. All
three papers received a good discussion.
Liverpool Chemists’ Association, Thursday, February
25. — Mr. A. C. Abraham, President, in the chair. — Mr. T. E".
Lescher, son of Mr. F. Harwood Lescher, and Mr. Charles Sharp,
F.L. S., were elected to membership. An interesting communi¬
cation respecting balsam of copaiba was made by Mr. Michael
Conroy, who said it was his wish to direct attention to the
large number of factitious samples of balsam which had recently
come under his notice. Of the adulterated samples but
few came from copaiba-producing districts, and in these
cases the adulterant was generally a fixed oil, easily
detected by its causing the residue left on evaporation to
be pasty and not easily powdered, as the genuine balsam residue
should be. In performing this test care should be taken that all
the essential oil is evaporated thoroughly, or the result with the
residue is apt to be misleading ; however, after a few experiments
with a genuine sample, there should be no difficulty with the test,
which is most reliable. Other samples he had examined were
entirely factitious, being made of common resin and oil of turpen¬
tine, and being offered at little more than half the market value of
genuine balsam. They responded to the evaporation test and those
of the Pharmacopoeia, but their true nature was readily detected by
their odour, particularly when gently warmed. Some samples, again,
offered at 3 d. or 4 d. per lb. below the market value of true copaiba bal¬
sam, were mixtures of genuine balsam and more or less of the factitious
article previously mentioned. These samples were the most diffi¬
cult to detect, in fact, if the adulteration be kept within certain
limits an expert even would easily be deceived. These balsams
are generally shipped from Hamburg to this country, and it is as
well for buyers to be on their guard against them. —In the discus¬
sion following, the President observed that Mr. Conroy had
rendered them a valuable service by bringing this important item
before them. The tests for balsam of copaiba had always appeared
to him to be somewhat open to criticism, and the balsams
under notice seem to have been adulterated with gurgun
balsam ; at least they gave him that impression. Had
Mr. Conroy tested for gurgun balsam? An interesting point
about this communication was that the only adulterants found in
the copaiba from South America were fixed oils, whilst all the
factitious samples were of continental origin. — Mr. Cowley
wished to know if Mr. Conroy had employed the American test,
consisting in dissolving the balsam in acetic acid, adding nitric
acid, and warming, when a purple colour would be formed if
gurgun balsam were present. Were not the physical constants of
use in determining the presence of adulterants? The resin
adulteration should show a high acid number Mr. Prosper H.
Marsden thought, and the specific gravity might be observed as a
guide. — Mr. Conroy, in replying, said he had not met with gurgun
balsam as an admixture in copaiba for many years. At one time it
was a very common adulterant. The test mentioned by Mr. Cowley
he had not tried, and as for the physical constants he would say
that nothing was more variable than copaiba, for good Maranham
yielded about 30 per cent, volatile oil, whilst Para contained 70 per
cent., the resin necessarily varying proportionately, hence with
such a wide difference it was impossible to rely upon the specific
gravity, etc. , as trustworthy guides. — Mr. J. Smith, local secretary
of the Pharmaceutical Society, pleaded for the Benevolent Fund
and the movement in connection therewith in celebration of the
Queen’s record reign. — The matter was referred to the Council
for consideration as to the best means for attaining the objects
Mr. Smith desired. — A paper was then read by Mr. Cowley on
“Vinum Colchici.” This appeared in last week’s Journal, page 173.
Bradford and District Chemists’ Association, Tues¬
day, March 2. — A lecture on “ Australia,” with lime-light illus¬
trations, was delivered before the members of the above Associa¬
tion by Mr. A. J. Bray, of Leicester, who has spent some
considerable time in the Australian Colonies. He gave a very
interesting account of the rise and development of the various
districts, and the industries peculiar to the different parts of the
Continent, illustrating his remarks with views of the early and
present condition of some of the principal towns, typical views of
gold mining, sheep and cattle farming, and the prolific vegetation
found there.
Midland Pharmaceutical Association Trade Com
mitee, Monday, March 1. — Mr. W. Jones in the chair. — The
following resolution was passed : —
“ That this Committee having considered the recent circular of Messrs. Elliman
re their new size of embrocation, are of opinion that the adoption of such a
course, especially after the firm’s many years’ labour in the opposite direction
will tend to damage not only the well-known reputation of the firm’s fair
and honourable dealing, but will also induce substitution and competition
where such is not now the case, and they hope Messrs. Elliman will see the
wisdom of placing their new size at once under their protection scheme, or
withdrawing it altogether.”
The Committee also had under consideration the carriage of
small parcels from London, and they hope to be able to make
satisfactory arrangements with the carriers for the benefit of
members.
SOCIAL MEETINGS-
School of Pharmacy, Friday, February 26. — The Students’
Annual Dinner was held in the Queen’s Room, Holborn
Restaurant, which was filled to its utmost limit by “ passed ”
and present students from the “ Square,” who had assembled
to partake of an excellent dinner. In previous years this event
has been connected with the Pharmaceutical Football Club,
but on this occasion it was thought advisable not to confine it
to the Club, but by associating the dinner with the School,
thus to include the whole of the students. The result proved to
be highly satisfactory, the affair being a great success. The Dean
of the School, Professor Greenish, occupied the chair, amongst
those present being the President, Mr. Walter Hills, Mr. Michael
Carteighe, Dr. B. H. Paul, Dr. J. Attfield, Messrs. R. Hamp-
son, J. Ince, E. M. Holmes, J. T. Humphrey, T. H. W . Idris,
G. B. Francis, J. C. Hyslop, J. Moss, A. C. Wootton, T. Morley
Taylor, R. G. Guyer, F. C. J. Bird, J. 0. Braithwaite, and
many others. The spur tables were presided over by Messrs.
R. Bremridge, Matthews, Robinson, Tebbutt, Dr. Lapworth, Pro¬
fessor J. Norman Collie, and Professor J. Reynolds Green.
— After dinner Professor Greenish proposed “ The Queen,” the
toast being enthusiastically responded to amid musical honours.
He then called upon Mr. M. Carteighe to propose the toast of the
evening, “ The School of Pharmacy.” — In the course of a bright
and witty speech, Mr. Carteighe gave a brief history of the
220
PHARMACEUTICAL JOURNAL.
[MARCH 6, 1897
School from its commencement, describing the difficulties
encountered by those who were anxious to make the School
thoroughly efficient for the training of technical pharmacists, and
dwelt at considerable length on the importance of a thorough
pharmaceutical education, mentioning as a proof that the School
of Pharmacy has been extremely successful in this direction, the
fact that since its establishment many distinguished men had been
turned out from the School, two of whom were present at the
dinner, in the persons of Ur. Paul and Mr. Joseph Ince. He knew that
in referring to Mr. Ince he was not saying that which was strictly
true, but although he was not in the School, he was of it. After
referring to the changes made in the School during the past year,
the speaker expressed his belief that as a result of the change, men
will be produced in the future who will be in the same position in
regard to pharmacy as the university men are in regard to medicine.
He saw no reason why in the future the School should not be
affiliated with the new Teaching University of London, and every¬
one who attended the complete course at the School be in touch
with the various degrees which that body will corfer.
Mr. Carteighe, speaking of the teaching staff of the School,
mentioned first the name of Professor J. Reynolds Green, observ¬
ing that the Council knew to their cost what a great interest he
took in his particular department, the biological operations of the
School having led to an enoi’mous increase in various forms of
expense, and when it came to the establishment of a histological
laboratory, Mr. Carteighe humorously remarked, ‘ ‘ My ! you
should have seen the faces of some of our colleagues on
the Council.” Nevertheless they formed the laboratory and
it had been of great service to the students. Referring
to Professor Greenish, Mr. Carteighe said, “ He is one of our
own boys, and I am very proud of him ; I am proud of him
because he has gone abroad, and by studying there has learnt
something of importance and is free from that insular prejudice
which so often characterises men educated in this country.” With
regard to Professor Collie he had some difficulty in saying all he
would like to say about him. He had heard him lecture, had seen
him in the laboratory, and had seen him working his blow-pipe.
Whatever Professor Collie did, he had a way of imparting instruc¬
tion which indicated that there are few things he does not know.
Speaking of the newly-appointed demonstrators, Ur. Lapworth and
Messrs. Ashby and Frye, and their old friends, Mr. Wilson and
Mr. Williams, he thought he was justified in saying that with the
assistance of these, the energy of the pupils, and the enthusiasm
the professors put into their work the Council have every reason
to hope that the opportunities for acquiring real knowledge are
certainly now to be attained in 17, Bloomsbury Square. The toast
was then heartily responded to.
Professor Greenish, in reply, thankedMr. Carteighe forthe kindly
way in which he had referred to those connected with the School
of Pharmacy. No one had taken more interest in the progress of
the School than the ex-President. When certain changes were
introduced in the histological department, no doubt the councillors
did pull a long face over it, but if it would be any consolation to
the present President, Mr. Hills, he (Mr. Greenish) might say that
very probably in the future there will be something wanted which
Will compel them to pull longer faces, it being necessary that the
education of the pharmacists should be carried further thanithas been
in the past, and therefore it is desirable and necessary that the
School should be properly equipped. The Council up to the
present had never hesitated to equip it properly, and he had no
doubt that although they might pull a long face, the necessary im¬
provements would be made. The School staff had their hearts
in the work and they all did their very best for the students —
In the name of his colleagues he thanked them heartily for the
enthusiastic way in which they had received the toast.
Mr. E. A. Umney, in replying on behalf of the students, said the
Pharmaceutical Society in founding the School and since had
always had at heart the perfection of pharmaceutical education,
as a result it was only necessary to look around to see that those
who hold the foremost positions in the pharmaceutical world are
in most instances * ‘ Square ” men.
Mr. F. A. Upsher Smith, Bell Scholar, in proposing “The Phar¬
maceutical Society,” referred to the past history of the Society
and the purpose for which it was organised. Comparing the pro¬
gress made by the Pharmaceutical Society since its formation in
1841 with its sister societies, the Society of Apothecaries, which
was incorporated in 1617, the College of Physicians, 1518, and
the College of Surgeons, 1460, Mr. Smith thought there was very
much hope for the younger Society. It was with great pleasure
he asked those present to drink to its success. The toast was
cordially received, the President replying.
Mr. Hills expressed his thanks for the kind way in which
the toast had been proposed and received, and said he was
exceedingly glad to meet the present scholars of the School on that
occasion, because he was one of the old scholars, although he
feared he was not a distinguished one. He had been raised to a
position which he felt his unworthiness to occupy, but he would
yield to no one in his desire to promote the higher education ol
pharmacists. His predecessor had referred to the time when
certain expenses were suggested with regard to the histological
laboratory, and in doing so had turned to him as though he was
one of those who objected to it. He thought his colleagues would
bear him out when he said that he was not one who kicked at that
expense. He was of opinion that no money of the corporate body
could be better spent than in the promotion of real and sound
education. Sometimes it was asked, “ What is the use of the
Pharmaceutical Society ? ” He did not propose to answer that
question in full, as he did not think the gentlemen
present wanted to be told that. One result of doing
away with the Society would be to relieve the President and
one or two others of a great deal of work. With respect to educa¬
tion, it seemed to him that their predecessors had not the diffi¬
culties to contend with that those of the present generation have
to meet. In the last generation, if a man had integrity, honesty,
industry, and common-sense business abilities, he made a very fair
income, but now something else is required. He thought that the
School of Pharmacy is now in a more hopeful position
than it has been at any previous time, and he hoped
that next year it will be in a still more satisfactory
position, seeing that the School is being worked on the
right lines and in the right direction. Nowadays more is
required than the old qualities of industry, integrity, etc. , and
he believed that in the future the knowledge gained at the School
will be of considerable commercial value to the students, and
the question of success will not depend so much as to whether
they get a halfpenny more or a halfpenny less for some proprietary
article, but will depend on those sciences on which the art of
pharmacy is founded, and on the fact that a man is a better and
more able pharmacist than his neighbours. He would also urge
upon all the necessity of supporting the Benevolent Fund, and
asked his young friends present not only to make the best use of
their time while at the School of Pharmacy, but to be loyal to the
Pharmaceutical Society, as it had done good work in the past, and
is capable of doing good work in the future.
Ur. J. Attfield then proposed the toast of “ The Old Students,
which was drunk with enthusiasm, Mr. Frederick Bascombe re¬
sponding. Professor Green, in a humorous speech, gave the toast
of “The Students’ Association,” Mr. Ashby and Mr. Wilson
replying. — Professor Collie, while proposing “The Football Club,
made several observations as to the practical use of sport of all
kinds. Mr. Matthews replied, and Mr. Wilfred Lean afterwards
proposed the health of the Chairman, which was received with
musical honours and briefly responded to. Uuring the evening an
excellent musical programme was carried out by Messrs. Rubeck,
Smorthwaite, Epton, Pettinger, Tebbutt, E. Umney, and Lean.
The proceedings terminated with a vote of thanks to the Secretary,
Mr. Tebbutt.
Cambridge Pharmaceutical Association, Friday, Feb¬
ruary 26. — The President, Mr. Alderman Beck, F.C.S., in the
chair. — A smoking concert was held at the Prince of Wales’ Hotel,
there being a good attendance of members and friends. — Mr. E.
Wethered, of Pembroke College, delighted the audience with his
remarkably able conjuring. The trick with the ring and pill-boxes,
being most appropriate for the occasion, caused much merriment.
The solution of a half-crown in a tumbler of water and the subse¬
quent finding of the same in a lemon, freshly cut, was equally
interesting and extraordinary, as was also the trick with a shilling
and envelopes made out of the covers of a weekly paper. Several
tricks with cards were successfully performed. The programme
included songs by Messrs. H. Uewhurst, A. L. Peel, A. F. Heald,
whose rendering of the “ Soldier’s Song ” was much appreciated,
A. G. Peck, E. Moss, Moore, and Greef. A banjo duet by Messrs.
Lockhart and Marshall was much enjoyed. Mr. C. J. Smart also
gave a recitation. Votes of thanks to the Chairman, the performers,
and the Hon. Sec., Mr. E. Saville Peck, concluded a most enjoy¬
able evening.
March 6, 1897]
PHARMACEUTICAL JOURNAL.
221
Edinburgh Pharmacy Students’ Supper, Friday, Feb¬
ruary 26.- — Mr. William Duncan, Principal, in the chair. — The
Ninth Annual Supper of the Pharmacy Students connected with
the Royal Dispensary School of Pharmacy took place in the West
End Cafe, Princes Street. Messrs. W. G. Mackenzie and C. M.
German acted as croupiers. About 80 were present, including
Messrs. J. Laidlaw Ewing, P. Boa, D. MacLaren, George Coull,
J. R. Hill, etc. The loyal toast being duly honoured, the Chairman
proposed “ The Pharmaceutical Society and the Boards of
Examiners,” which was replied to by Mr. J. Laidlaw Ewing,
Chairman of the N. B. Executive and of the Board of
Examiners for Scotland. In his reply Mr. Ewing drew
special attention to the claims of the Benevolent Fund,
.and the effort that was being made in connection with the
Diamond Jubilee of Queen Victoria’s reign. On a happy sugges¬
tion of the Chairman a collection for the Fund was immediately
.taken, amounting to £2 15s. 4 d., and later in the evening a
gentleman handed another sum of 10s. to Mr. Hill for the Fund.
The other toasts were “The Pharmaey Students,” proposed by
Mr. D. MacLaren and acknowledged by the Chairman ; “ The
Ladies,” proposed by Mr. W. E. Pilgrim and acknowledged by
Mr. P. Boa; and the “Chairman and Croupiers,” proposed by
Mr. G. Coull and acknowledged by the Chairman. In the course
■of the evening Messrs. Haley, Gilchrist, and England, on behalf of
their fellow-students, presented to Messrs. Duncan, Mackenzie,
And German, respectively, a silver tea-urn, a silver ink-stand, and
.a gold pencil case, as a token of esteem. With vocal and instru¬
mental music and recitations, a most enjoyable evening was spent,
.and the end of the programme was reached at 1 a.m.
NEW REMEDIES.
[The notes given under this heading embody recent suggestions in
Aherapeutics. They cover both new drugs and preparations, and old ones
under new aspects. The word "parts” is used to represent parts by
weight, both for solids and liquids .]
Cacodyl Compounds for Therapeutic Use. — Acidum caco-
-dylicum (dimethyl-arsenic acid), As(CH.3)20(0H), forms odourless,
oblique, rhombic prisms which are easily soluble in water and
alcohol, and which melt at 200° C. Sodium cacodylicum,
As(CH;!).2ONa, is an amorphous white powder, soluble in water,
and is recommended in place of the usual arsenic compounds.
Doses of 025 centigramme internally, or 10 centigrammes sub-
cutane are well borne. — Pharm. Zeit., xlii., 106.
Benzacetin as an Anti-Neuralgic and Anodyne (phenacetine-
‘carbonic acid, or acetamidosalicylic acid). — Occurs in colourless
•crystalline needles, difficult to solve in water, easily soluble in
alcohol ; melting point 205° C. Benzacetin forms salts with bases
which are easily soluble in water, such as lithium benzacetin. Both
the pure benzacetin and the lithium salts are promptly effective
for neuralgia. Doses of 0'5 to 1 '0 Gm. are ordered for sleepless¬
ness and nervous excitement. — Pharm. Zeit., xlii., 107.
Creosote in the Treatment of Pleuro-Peritoneal Tuber¬
culosis in Children. — Thoma has given the following enemata
for the treatment of pleuro-peritoneal tuberculosis in children. At
the outset each enema contained 150 grammes of emulsified cod-
liver oil and 0’5 gramme of creosote, but after from eight to ten
days 1 gramme of creosote. In the first case Thoma gave in the
-course of a few days 1 5 gramme creosote ; diarrhoea ensued, and
the enemata had to be discontinued. After a few weeks it is as
well to suspend the treatment for five or six days and begin again.
The taste of the creosote did not appear to be noticed by the
children ; the appetite was at first slightly impaired, but subse¬
quently improved. By this method it is possible to reKeve the
-/disorder of the bowels so frequent in this illness. Thoma states
in conclusion that it is, of course, inexpedient to generalise from
,two cases as given in his experience, especially as the children were
not very ill and were treated promptly ; but keeping in mind the
comparatively short duration of the treatment and the necessity
for preserving the appetite and the digestive functions as unim¬
paired as possible, it appears that enemata of cod-liver oil and
creosote are well tolerated and give good results. — Lancet, i., 97,
159.
LEGAL INTELLIGENCE.
PROCEEDINGS UNDER THE PHARMACY ACT.
Prosecution at Airdrie.
At the Sheriff Court House, Airdrie, on Monday, March 1, the
case of Bremridge v. David Lees, came before Sheriff Mair for trial
(see ante, p. 194).
Mr. T. B. Morison, advocate, Edinburgh, and Mr. R. Watt,
solicitor, Airdrie, appeared for the prosecutor, and Mr. Brock,
writer, Glasgow, for the defendant.
Before witnesses were called Mr. Brock asked the Sheriff to
amend the complaint in accordance with his ruling at the pleading
diet, so that the words “recited Act” should read “the Phar¬
macy Act, 1868.” The Sheriff declined to make the alteration.
Mr. Brock then produced a medical certificate to show that one
of his witnesses for the defence was seriously ill, and his absence
would prejudice his client’s defence.
Mr. Morison said he would not found his case on anything
the witness could speak to, and his absence would make no
difference.
The Sheriff declined to adjourn the case.
J. Rutherford Hill deposed that he was instructed by the
Registrar to make enquiry and institute proceedings in this case.
He produced the Register of Chemists and Druggists for 1896 to
prove that David Lees, the defendant, was not duly registered.
He also produced the two bottles of laudanum and the bottle
of Powell’s balsam mentioned in the complaint. These he
had analysed and found about two fluid drachms of
laudanum, equivalent to about 8 grains of opium, in each of the
two bottles, and in the Powell’s balsam of aniseed not less and
probably more than 0T grain of morphine, equal to 1 grain of
opium. All three bottles were duly labelled poison, and had on
them the address of the seller. There was a recorded case in which
2 fluid drachms of laudanum had proved fatal to an adult. One
grain of opium had killed an aged person. One-sixtieth of a grain
of opium had killed a child. In cross-examination, Mr. Hill said
it was not correct to describe laudanum as not containing opium,
it was practically a solution of opium in proof spirit. What was
not dissolved consisted almost entirely of inert matter and impurities
which got mixed with the opium in the process of gathering it. If
the proof spirit were evaporated off, what remained could be pretty
accurately described as purified opium. It would be most mislead¬
ing to say laudanum contained no opium. He had not attempted
to ascertain the ingredients of balsam of aniseed other than the
morphine, which he had carefully separated in the solid state. He
thought some of the other ingredients were liquorice, balsam of
tolu and oil of anise. It was not a patent medicine, and he was
surprised to hear that any one at this time of day should think it
was. It was a proprietary medicine and for that reason bore a
government stamp as provided by the Medicine Stamp Act.
Mr. Brock attempted to make the witness produce confidential
correspondence passing between witness and the Registrar and the
local Secretary, Mr. Harvie, to support his opinion that the prosecu¬
tion was not in the public interest but merely a piece of personal
animus between Mr. Harvie and Dr. Arthur, in whose shop the
poisons were sold.
Mr. Morison objected to any such evidence, and the Sheriff
refused to allow it.
Alexander Spence and Joseph Tait proved the sale of the poisons
by the accused.
Mr. Morison said that was his case.
Mr. Brock said he had now to state three objections as a bar to
this case being sustained. He could not rightly state these
objections till he saw the evidence against him. His first objection
was that the prosecutor must attend and produce his evidence
, that he had been duly appointed as Registrar, and the date of his
' appointment. Secondly, the complainer said the offence was com¬
mitted at or near the shop, but it was proved that it was committed
in the shop. The locus, therefore, was not correctly stated, and
that had been held fatal in a case of day poaching, where the
offence was said to have been committed at or near a wood.
Thirdly, the Register produced was not properly authenticated as
correct as the original Register specified in the Act, and was,
therefore, of no use as evidence.
The Sheriff repelled all three objections.
For the defence Mr. Scotland, burgh assessor, was called to prove
222
PHARMACEUTICAL JOURNAL.
[March 6, 1897.
that the tenant of the shop 1, High Street, was Dr. Arthur, and the
proprietrix, his wife, Mrs. Arthur.
Mr. Thomas Hart registered chemist, deposed that he had
always regarded Powell’s balsam as a patent medicine. He
thought all medicines bearing the Goverment stamp were patent
medicines. In cross-examination he said he had never seen or
heard of letters patent for Powell’s balsam, and he admitted that
he had no clear idea of the difference between a proprietary and
a patent medicine.
Mr. John Harvie, chemist and local secretary, Airdrie, said he
was a member of the Pharmaceutical Society. Shown a bottle
bearing his name and the words “ Astringent mixture,” he said
it was not a proprietary medicine. He declined to state its con¬
tents. Powell’s balsam was a proprietary but not a patent medicine.
Mr. Brock : Your assistants are unqualified ; are they, Mr.
Harvie ?
Mr. Morison : I object to this question, and to the whole line of
interrogation by which Mr. Brock has repeatedly attempted to
drag in the affairs of third parties to-day. These have no bearing
whatever on this case, and we have nothing whatever to do with
them here.
Mr. Brock : I am entitled to show, my Lord, that this is not a
bond-fide prosecution but persecution by Mr. Harvie, who has been
making offensive charges against Dr. Arthur in connection with
medicines supplied to the hospital in his capacity as a town
councillor, and has been boasting of what he would do to Dr. Arthur.
The Sheriff : I refuse to allow these questions to be put. Any
amount of animus will make no difference in the case of a charge
of this kind.
Dr. Arthur said Lees was an apprentice with him, and had been
about a year at the business. He had always wished to have a
qualified assistant to keep his shop, but he had found it quite
impossible to get one. He was five or six times in the shop every
day, and his medical assistant would be as often in, and he thought
that was quite sufficient supervision. He thought he must have
been in the shop when the laudanum was sold. Laudanum did
not contain opium, and was not a preparation of opium. You
might as well say that cheese was a preparation of milk, or that
beer was a preparation of hops. Powell’s balsam, he thought, was
a patent medicine, and it was so described in the invoices of the
wholesale house who supplied him. Mr. McAdam, of the Glasgow
Apothecaries’ Company, had told him it was impossible to get a
qualified assistant for him.
Mr. Morison then asked for a conviction Dr. Arthur was per¬
fectly aware of the requirements of the Pharmacy Acts, and this
was an open and flagrant defiance of the law. He therefore asked
for the full penalty and costs.
Mr. Brock said the prosecution had miserably failed and he
pressed now all his objections. Looking to the Act of 1868 he said
no charge could be made against a doctor’s assistant, and he held
that all the judges were wrong on this point. He therefore asked
that the charges be found not proven.
The Sheriff said the case was an important one. Fortunately
most of the arguments for the defence had already been disposed of
by authority which could not be disputed. He would not person¬
ally express any view as to the policy of the Pharmacy Acts.
Having cited the judgments in the English Courts and in Tomlin¬
son’s case in the Scotch Courts, he said that, though he had grave
doubts as to what was the real interpretation of the Pharmacy Act,
1868, he could not in face of these decisions come to any other
conclusion than that the offences charged were relevant and had
been clearly proved. This was the first case of a doctor’s assistant
that had been before him, and he thought it would be sufficient to
impose a penalty of 5s. for each of the first two offences, and 10s.
for the third offence, with £2 for expenses.
Mr. Brock intimated that the case would be appealed to the High
Court of Justiciary.
Police Prosecution under Section 17.
At Bow Street Police Court on Saturday last, before Mr. Lush-
ington, Joseph Wallace, homoeopathic practitioner, of 4, Albany
Terrace, Regent’s Park, and Arthur Russell Salsburjq bookseller,
Oxford Street, were summoned for selling a poisonous drug to a
person unknown to them without inquiry, without labelling it as a
poison, and without being registered under the Pharmacy Act.
Mr. Bodkin prosecuted for the Treasury, and Mr. Young defended.
Mr. Bodkin said that in consequence of information received a
detective was sent by the Treasury, on November 16, to visit the
defendant Wallace at his house in Albany Terrace, Regent’s Park,
where a medical periodical was published, devoted, among other
things, to the recommendation of “ Wallace’s Specifics.” The one
in respect of which these summonses were issued was known as
Specific No. 1. Detective-sergeant Boswell told Wallace he was
investigating a case of death said to be caused by taking this
specific. Wallace supplied him with a bottle of the medicine,
after affixing a medicine duty stamp and a label bearing the word
“Poison.” On January 12 Detective-sergeant Allum went to the
house of the same defendant and asked for a bottle of the same
mixture, saying he had been sent by a chemist. He was supplied
without inquiry with one of the bottles, on which there was no
poison label. The bottles were handed to Dr. Luff, one of the
official analysts to the Home Office, and he found that the prepara¬
tion contained a considerable proportion of aconitine, the quantity
present being such that one-sixth of the contents of the bottle
might probably prove fatal, and a whole bottle would mean almost
certain death. At any rate the contents of the bottles were such
as to bring the medicine within the scope of the Act.
Francis Boswell, a detective-sergeant in the S Division, stated
that on November 16, in company with Sergeant Dixon, he went
to Wallace’s house. Witness told him he was a detective-sergeant,
and asked him if he was a proprietor of Wallace’s No. 1 specific,
which was supposed to have caused the death of a gentleman in
London. Mr. Wallace said he very much regretted the gentle¬
man’s death. He stated that, theoretically, it was a poison, but
practically not. Mr. Wallace denied that anyone had died from
drinking his specifics, and said it was more probable the man had
died from taking other drugs, and that he had probably drunk
something in mistake for rum. Deceased had drunk Wallace’s
specific in mistake for rum and afterwards died.
Detective-sergeant Allum, of the S Division, stated that on
January 12 he went to Mr. Wallace’s house and asked for
Wallace’s No. 1 specific. Mr. Wallace at once handed him a
bottle of the specific, for which witness paid. It was not labelled
“ Poison.”
Formal evidence was given to show that Mr. Wallace is not a
member of the Pharmaceutical Society.
Dr. Arthur Luff, one of the official analysts to the Home Office,
stated that he received, on January 15, a bottle from Detective-
sergeant Boswell. It contained a fluid ounce of brownish liquid.
He tested it in various ways, and came to the conclusion that it
contained aconitine. The equivalent of one-sixth of an ounce of
tincture of aconite had proved a fatal dose, and he had found that
this specific and tincture of aconite produced identical effects.
Aconitine was probably the most active poison known.
Mr. Young, for the defence, said the preparation was not
considered a poison. Aconitine was present, but only in infinitesimal
quantities. The defendant Wallace was a homoeopathic chemist,
and said it was against his principles to employ such a drug except*
in the most minute proportions.
Mr. John B. Coppock, of Preston, analyst to the Lancashire
County Council, said it would require about thirteen bottles of this
mixture to provide a fatal dose. He was of opinion that one bottle
would not do an adult any harm.
Mr. Lushington said it was evident from the evidence of Dr.
Luff that the mixture contained more than an infinitesimal quantity
of poison. It had been suggested that Mr. Wallace might get out*
of that difficulty by making the mixture a patent medicine.
Possibly he might do so, but in that case he would have to make a
disclosure as to what the medicine was composed of. Until that
was done, it was his duty -to label every bottle “ poison,” and to
make an entry in a proper book of the persons to whom he sold it.
Mr. Wallace would be fined £5 and £10 10s. costs on the first
summons, and £5 and 2s. costs on the second. The Magistrate
ordered Salsbury to pay £2 10s. with respect to each of the two
summonses.
OBITUARY.
Howard. — On February 4, George Howard, chemist and druggist,
Hooley Hill, Lancs. Aged 55.
Sanson.- — On February 24, Edwin Sanson, chemist and druggist,
Barrow-in-Furness. Aged 60. Mr. Sanson was one of the
oldest tradesmen in Barrow, and in 1887 was elected a member
of the Town Council, retiring from office in 1890, without-
seeking re-election. The funeral took place on Friday, Febru¬
ary 26, and was largely attended by tradesmen and the lead¬
ing men of the town.
March 6, 1897.]
PHARMACEUTICAL JOURNAL*
223
LETTERS TO THE EDITOR.
Solubility of Iodine in Cod-Liver Oil.
Sir, — In reply to Mr. Gibson’s inquiry about cod-liver oil and
iodine, the oil contains large but somewhat variable quantities of
unsaturated fatty acids, which more or less readily combine with
the free iodine. Unless the iodine is in excess of the amount
required by these acids, the colour will be discharged. The fact
that cod-liver oil will absoi’b the iodine is not a very serious
matter from the therapeutical standpoint, though, of course, to a
pharmacist who desires to dispense an article uniform in appear¬
ance it is somewhat annoying to find the brown tint disappearing.
As far as my experience goes, the only remedy lies in taking the
precaution, if possible, of always using the same oil or, at any
rate, oil of the same quality, and also to stock the preparation in
dark blue bottles with as little exposure to the light as possible.
London , March 2, 1897. R. Glode Guyer.
Sir, —Shortly before leaving Weymouth and practical pharmacy
I made some experiments on the combination of iodine with fatty
•oils, but before I had gone very far my notes mysteriously dis¬
appeared, and the inquiry came to a sudden end. A few months
later I was at the Antipodes among the kangaroos. I must there¬
fore trust to my memory for the little information I can give to
Mr. Gibson. My attention was called to the subject by observing
that a solution of iodine in carbon bisulphide and olive oil was
gradually losing colour, which, indeed, finally disappeared under
the influence of diffused light, the containing vessel being full and
well corked. Several other oils were found to exhibit the same
reaction, but not all with the same intensity. Almond oil was the
best, then came olive, cod-liver, and castor. The carbon bisul¬
phide having been evaporated by a very gentle heat aided by a
current of air, the oils proved tasteless so far as iodine was con¬
cerned. Chloroform was tried, and proved as effective, as the
bisulphide was not so easily got rid of. I cannot remember the
proportions I employed, but perhaps 4 grs. of iodine to the fluid
ounce would be near the mark. A curious property of these
solutions, or, more correctly, combinations, was the fact that when
heated carefully by water-bath to a moderate temperature, say
120° F., the iodine was thrown out of combination and the colour
restored. Whether if left to itself for a time, greater or less, the
solution would have recovered its colour I had not an opportunity
of ascertaining. I think not. I found that prolonged keeping (for
two months perhaps) developed a little colour, which I attributed
to oxidation through imperfect corking. It would be interesting
to have these points cleared up by Mr. Gibson if he has the time,
or possibly by the Research Laboratory officials.
Poole, March 2, 1897. Thos. B. Groves.
Unguentum Hydrargyri Nitrates.
Sir,— Anything that comes from the pen of Mr. P. W. Squire
deserves to be regarded with the utmost respect, and I have
therefore read with great interest his communication on the above
subject in your issue of the 27th ult. It was, I believe, at my
suggestion, made some fourteen years ago, that the directions for
preparing this ointment were modified in the 1885 B.P. The 1867
edition directed the acid solution of mercury to be added to the
lard and oil while both were “hot,” the temperature being
increased till the necessary frothing took place. I proposed, in
■order to ensure uniformity in the ointment, that the temperature
be definitely fixed at 212° F., and this was done. The experience
of many years has, however, convinced me that the specifying of
the temperature was unnecessary, because the temperature must
always rise considerably above 212° F. before sufficient frothing
takes place. It really, therefore, does not matter very much
whether the solution of nitrate of mercury be added when the
fats are a few degrees under, or for that matter a few degrees
over 212° F.
It is a question, regarding which difference of opinion may exist,
as to what ought to be the nature of this ointment, and doubtless
every pharmacist must in the end be guided by his own judgment.
Taking the history of the ointment as my guide I have for myself
concluded that it ought to be as nearly neutral as possible :
Certainly that it ought not to be excessively acid. It was re¬
commended in the old dispensatories as an eye ointment, and
clearly no eye could possibly receive any benefit from the application
of an ointment containing a considerable percentage of free nitric
acid. If we grant this condition there need be no difficulty about
temperature, for it stands to reason that the higher the temperature
employed the less free acid will there be in the ointment. I noticed
this very clearly in my experiments fifteen years ago, and ever
since I have used a fairly high temperature, in no case certainly
lower than 211° F.
It will be gathered from these remarks that there are some
points on which I differ from Mr. Squire. I do not find for instance,
and never have found, that a high temperature during the process
darkens the ointment. I have repeatedly made it at a very high
temperature, using an oil bath for example, and since Mr. Squire’s
article appeared I have made several experimental batches at from
300° F. to 350° F., and in every case the colour and consistency are
simply perfect. I admit that prolonged heating will decompose
the ointment, but decomposition should not take place so long as
there remains any free nitric acid, and long before the acid is driven
off it is perfectly certain that all frothing or “ effervescence ” must
have ceased,
Nor do I agree with Mr. Squire’s suggested process. I have
always held that the U.S.P. process — adding the mercuric nitrate
solution after the ointment has cooled— was bad, and Mr. Squire’s
is not much better. An ointment so prepared must be, from the
very nature of the case, exceedingly acid ; it is, in fact, an oint¬
ment of mercuric nitrate plus free nitric acid. No doubt citrine
ointment always does contain some free acid, but, as I have already
said, the less it contains the better ; with this proviso, however,
that an absolutely neutral ointment is not to be desired, inasmuch
as its keeping properties would be very poor, and, moreover, such
an ointment could not be satisfactorily made by the present
method. An ointment prepared according to Mr. Squire’s process
looks very well, and, I should say, will keep very well, but it is, I
think, too acid. I have made quite a large number of samples
during the last two days, and I have estimated the percentage of
free nitric acid in three of these. Taking the mean of three deter¬
minations, in each case I find that a sample of ointment prepared
by Mr. Squire’s process contains 3 '78 per cent, of real nitric acid ;
a B.P. ointment contains 3*0 per cent., and an ointment prepared
at an initial temperature of 300° F. contains 2d per cent. Person¬
ally, I prefer the last of the three.
Mr. Squire thinks “ it is important that the temperature should
be kept as low as possible after the addition of the mercuric solu¬
tion ” ; but here again I disagree. The temperature should be
sufficiently high to cause free frothing after the mercuric solution
is added. Were the mercuric nitrate solution a neutral one, or
even only slightly acid, his suggestion might be adopted, but with
a strongly acid solution, such as is employed, the result could not
but be, in my opinion, very unsatisfactory.
With all deference, therefore, I submit that the adoption of the
suggestion put forward by Mr. Squire would be a retrograde step.
Hawiclc, March 2, 1897. Thos. Maben.
Adulterated Saffron.
Sir, — I have just seen a sample of croci stig. (not my own,
luckily) certified by analyst to contain 36 per cent, of BaS04, and
find him correct. This was obtained from a city house of first-class
repute, and my note may induce brother pharmacists to look up
their stock.
March 1, 1897. Verb. Sap (83/14).
The P.A.T.A.
Sir, — In opening the case for the P.A.T.A. Mr. Johnston intro¬
duces the “ average chemist — the kind composing the bulk of the
craft ” — and makes him dance to music which is of his own (Mr. J.’s)
setting, and which, I believe, the average chemist cannot follow.
Mr. Johnston says, “ I know very well that he could persuade his
customers to have his own preparations twenty times in the hun¬
dred, but how about the other 80 per cent. ? ” Does this mean that
the average chemist has a number of preparations of his own,
representing so many of the advertised nostrums, and that he is
able to sell his own when another is asked for to the extent of 20
per cent, of all orders for proprietary articles ? Or does it mean
that the average chemist covers the whole of the ground with his
substitutes (imitations would be a better word), tackles even “ th*
worst specimens of cut goods,” but fails in four cases out of every
five ? In either case I deny that those composing the bulk of the
craft are such a herd of imitators. Will your readers allow Mr.
J ohnston’s type of the average chemist to pass unchallenged ?
March 1, 1897. Midlothian (83/14).
224
PHARMACEUTICAL JOURNAL.
[MARCH 6, 1897.
On Check Tills.
Sir, — I can endorse the remarks made by two correspondents in
the Journal re “ O’Brien’s Check Till,” as the most suitable one in
the market at present for chemist’s use. I see another correspondent
has brought before your notice the “ National Cash Register,”
which, he says is perfection. I quite agree with him, but the cost
is out of all proportion to the advantages to be derived from its
use. I would not be surprised any day at seeing introduced by
some American firm a till on the principle of the “National Cash
Register,” at say £10. I do not write without experience of each
of the above tills, as in the last pharmacy I was in there were two
“ National Cash Registers” at the counter and an O’Brien at the
compounding department.
Belfast , March 1, 1897. Saml. Hogg.
Sir, — Referring to a letter signed “E. A. Holloway” in last week's
admirable issue, I beg to say that £50 appears to me quite an un¬
necessary price to pay for a check till, as I have been using for
more than two years one made by T. O’Brien, Liverpool (for which
I paid the modest price of £3), and I find it answers every purpose
for checking required in a chemist’s business, being worked with
ease and rapidity. I observe this till is advertised in the Journal
of February 27, and also that Mr. O’Brien sends it on trial for
fourteen days. “ Enquirer ” can therefore try one without risk.
Exeter , March 1, 1897. J. Bartleet.
Sweating the Dispenser.
Sir, — In reply to a letter signed “Anti-Sweater,” I hope you
will kindly give me space for a few remarks. I agree with him
that we are worked too hard and the pay is inadequate, but I must
take exception to his explanation of how the work is done. I have
been dispenser at several large institutions in London for the last
fourteen years, and nine of those years have been divided between
three of the largest infirmaries. I have always weighed or
measured every powder or liquid, and have never met with any
dispenser who guessed. As your correspondent says he visited one
of these institutions (infirmaries) to see “ how it was done,” he
must have made a very unhappy choice, and I think
in fairness to us all he ought to give the name of the
infirmary where such gross negligence existed. If the dis¬
penser has no self-respect, where was the medical superintendent,
whose duty it is to see after this department, and what price the
Government inspector ? I am sure if the Local Government Board
were acquainted with the facts of the case they would soon cause
an inquiry to be made, and someone would suffer. I should be
glad to know if the dispenser in question is a lady, one of the
Army qualification, or a qualified chemist. I am no novice at the
work, and yesterday dispensed 360 prescriptions. The Editor has
my name and address, and is at liberty to give it to “Anti-
Sweater,” and if he would come and see me at any time in hours
(9 to 6) I should be glad to prove to him that, although we (as quali¬
fied chemists) are so inadequately paid, yet the dispensing is
carried out conscientiously.
February 16, 1897. “ Dispenser ” (81/35).
Holiday Science.
Sir, — The very sensible proposals made under the heading
“Natural History Notes” in your special issue are I think cal¬
culated to improve the personal interest taken in the Journal. It
has occurred to me before now that it would be interesting if members
of the trade could be induced to communicate to you the names of
the subjects and special departments of these which interest
them in matters scientific (or even literary and artistic) outside
as well as directly bearing on pharmacy. By sending to you
under one cover as many separate cards — p.c. size — and each
with separate address, as represent the subjects presently and
actively interesting the subscriber, you might find time to assort
these and communicate the results in one form or another to your
readers. In order to protect contributors it might be as well to
stipulate that a corner of the card should be cut off when it was
desired to remain anonymous, adopting at the same time a nom de
‘ plume ; while those who were disposed to be active or helpful, if
occasion arose, might attach the word “active ” to theirs. If this
suggestion approves itself to you, I think, considering the very
intelligent interest manifested in philological subjects on a recent
occasion, that you should make the range of subjects include as
large a field as possible in literature, science, and art.
March 1, 1897. “ ScoTcn Chemist” (83/12).
*** We are always glad to receive suggestions from readers, and to learn the
nature of the information that interests them more particularly. Accord¬
ingly, communications of the nature suggested will.be gladly received.
[Editor, P.J. ]
ANSWERS TO QUERIES.
Copra.— This is the name given to the dried kernels of the coco
nut. [ Reply to Pharmacist. — 81/21.]
Poor Law Dispensership. — Apply to the Secretary, Local
Government Board, Whitehall, S.W. [ Reply to J. F. — 82/36.]
Minor Examination. — You must be twenty-one years old before-
presenting yourself for this examination. [Reply to R. C. — 82/38. ]
Book on Decimals. — We do not know the book you mentions,
[Reply to S. H.— 83/8.]
Pereira Medal.— There is no practical test imposed in the
examination. [Reply to W. A. K. — 83,3.]
Names of Surgeons. — We cannot undertake to give recom¬
mendations in such cases. Ask your local medical man. [Reply/
to G. A. T.— 83,24.]
Edison-Lalande Battery. — The paragraph you quote contained
an obvious mistake ; it should have specified six Edison-Lalande.
cells, not one. [Reply to Volta. — 80/23.]
Metol. — This is the sulphate, hydrochlorate or oxalate of
mono-methyl-para-amido-meta-cresol, which has the formula —
C6H3OHCH3NHCH3. [Reply to W. B. L.— 81/5.]
Milk Preservative.— If anything has been added to milk for
preservative purposes, the seller will be liable to prosecution under
the Sale of Food and Drugs Acts. The only plan that can safely
be resorted to is to sterilise the milk and preserve it in sealed;
bottles. [Reply to Lactis. — 82/4.]
Jalapin. — The information you require is given in Squire’s;
1 Companion,’ the ‘ Extra Pharmacopoeia,’ Attfield’s ‘ Chemistry,2
and other works of reference, some one of which you ought to have,
access to. Our space must be reserved for information that is not.
so readily available. [Reply to S. H.— 81/26.]
[Several Answers to Queries are unavoidably held
over.]
CORRECTIONS.
Benevolent Fund List. — The Secretary desires us to notify'
the following corrections in the Local List of Subscriptions and
Donations received during 1896, prepared by him and published
with last week’s Pharmaceutical Journal
Lockerbie, James, is of Edinburgh, not Dumfries.
Nuthall, Edwin (Norwich). The name was mis-spelt NuttalL
Williams, Stephen, is of Hove, not Bristol.
Woolley, S. W., London, 5s. This name was omitted.
Coca-Kola Wine. — Messrs. Potter and Clarke point out that
the bottles containing this wine are Apollinaris Pints, and contain
almost a pint each instead of half a pint as stated last week. The
wine can be sold without a licence.
PUBLICATION RECEIVED.
Tannalbin. Pp. 16. Knoll and Co., Chemische Fabrik, Lud-
WIGSHAFEN, a/Rh.
COMMUNICATIONS, LETTERS, etc., have been received from
Messrs. Austen, Barrass, Bartleet, Baxter, Bird, Brawn, Buckley, Bullivant,
Clarke, Coats, Cowley, Cummings, Farr, Faulkner, Forret, Glyn-Jones, Goodall,
Groves, Guyer, Harris, Henry, Hill, Hogg, Jones, Keen, Kemp, Knight, Maben„
Macaulay, Moore, Moultrie, Nuthall, Pearson, Philip, Pike, Potter, Smith
Thompson, Waddington, Warrell.
PHARMACEUTICAL JOURNAL
225
March 13, J897J
THE COMMERCIAL VA1
lAL OILS.
C. UMNEY.
37 ft
[ETIES OF FENNEL AND
BY, 4 d?
In a' coSn^tmiciiti-Oiv ma$Wro the British Pharmaceutical Con¬
ference at ihv(*'j6b(|}, <\fyo(Pharrn. Journ. [4], iii., 91), I gave the
principal characfjbf?ToF Japanese fennel and its essential oil. I also
noted some comparisons between this particular variety and the
French and Indian fennels and their essential oils.
A specimen of the Japanese fennel fruit had been previously
examined and reported upon by Mr. Holmes ( Pharm . Journ. [3],
x. , 262), who stated that it had a taste at first strongly resembling
that of anise.
The shipment, reported on at Liverpool, was described as
“anise” by the firm of drug brokers who offered it for sale. The
smallness of the fruit was misleading to a casual observer, and it
was not surprising that the fruits were, in the hurry of business,
mistaken. •
Mr. Kirkby subsequently, in a letter to the Ph. J. [4], iii., 175,
expressed doubt as to whether the mis-naming was wholly to be
attributed to this cause, and he questioned whether it was not
rather due to a nearer approach than usual to the anise odour.
He also recorded observations on a sample obtained from
a shipment of Roumanian seeds which he had examined, and
which agreed in every particular as to form and structure with
fennel, the average length being 4 Mm. , and the odour decidedly
anise like. He concluded his letter with the question, “ Is there
a variety of fennel having a small fruit, and having a more pro¬
nounced anise odour than the larger kind usually found in
commerce ? ”
As so many varieties of large and small fennel exist, and as the
genus from which the fruits are obtained is a very widely distri¬
buted one, I thought that considerable differences were not
improbable, and with the object of making a comparison of all
obtairable varieties, I have procured fruits from as many countries
as possible, and from them distilled the essential oils.
The principal use for fennel is as an ingredient in compound
liquorice powder, for which purpose it is included in the British
Pharmacopoeia, and for this the demand is considerable.
It is also' official in the Pharmacopoeias of Austria, Bel¬
gium, Denmark, Holland, France, Germany, Hungary, Norway,
Italy, Portugal, Russia, Spain, Sweden, Switzerland, and the
United States.
While the oil is unofficial in the British Pharmacopoeia, and is
but little used in this country, it nevertheless finds a place in all
the pharmacopoeias enumerated (the Italian only excepted), and is in
considerable demand on the Continent of Europe. It is used in
the United States Pharmacopoeia in place of the fruits in compound
liquorice powder to obviate the difficulty that is experienced in
grinding fennel rich in essential oil to fine powder, unless it be
operated upon with the sulphur and sugar placed under suitable
millstones.
The descriptions of the fruits differ, and whilst the German
Pharmacopoeia III. describes the fruit as about 8 Mm. long)
doubtless intended to be the Saxon variety, the United States
Pharmacopoeia says 4 to 8 Mm. , and the British Pharmacopoeia
from 1/5 to 2/5 inches, which would include almost all the
varieties, both small and large, many of which would be
excluded by the description of the German Pharmacopoeia.
The principal source of the oil distilled in Germany is not how¬
ever the Saxon fruits, because their fine appearance causes them
to realise a price for druggists’ use, out of proportion to their
essential oil value, unless, as sometimes happens, the crop is
Von. LVHI. (Fourth Series, Yol. IV.). No. 1394.
sufficiently plentiful to compete in price with those of Galicia,
Southern Russia, and Roumania.
Fennel is indigenous to the countries bordering the Medi¬
terranean, but extends to Britain on the north and to Persia and
India on the south, and China and Japan in the east ; with the
exception of India, these countries fall within 25 degrees of
latitude (30° to 55° N. ), and the apparent unsuitability of the
hotter climate of India to the fruit will be referred to subsequently.
All the better known varieties are ascribed to F. capillaceum, with
the exception of the Indian fruit, which is referred to F. pan-
morium, D. C., although this even is generally regarded as a variety
only of F. capillaceum. The Sicilian variety of fennel is referred
to F. piperitum, and the Japanese variety cannot be definitely
determined until the plants grown from them, of which two are
exhibited, are more fully developed.
The fruits vary considerably in size, the smallest (Japanese) being
about 3 to 4 Mm. in length, whilst the largest (the Saxon) are
frequently 10 Mm. in length.
The first table shows the comparative sizes of the different
varieties of fruits, as well as other characters, and also their
respective yields of essential oil.
Fennel Fruits.
Variety.
Average
length.
Average
length of
vittse
in transve
Average
breadth of
vittse
rse section
Percentage
of oil.
Odour and taste
of oil.
Mm.
Mm.
Mm.
1. French (sweet) . .
7-8
•11
•04 to -05
2-1
Sweet, anise¬
like, and fatty
2. ,, (bitter) . .
4-5
•18 to -2
•07 to '08
Not distilled
—
3. German (Saxon). .
8-10
•2 to "22
"07 to '08
4-7
Sweet and very
camphoraceous.
4. Indian .
6-7
•1
•03 to -04
•72
Sweet and anise¬
like
5. Russian .
4-5
•2
•04 to -05
4-8
Very camphor*
aceous
6. Galician .
5-6
•2 to -22
•08 to '10
4-4
Very camphor¬
aceous
7. Persian .
6-7
•15
•05
1:7
Sweet and anise¬
like
8. Japanese .
3-4
•15 to -16
•07 to -OS
2-7
Very sweet and
camphoraceous
Description op Fruits.
French (sweet). — The fruits (Nos. 2 and 9) are oblong, cylindrical,
about 2 to 3 Mm. in width, frequently slightly arched, and from
7 to 8 Mm. in length, very prominent ridges, with smooth surfaces,
and a pale yellowish-green colour.
French (bitter).- — The fruits (No. 5) are usually only about 4 to
5 Mm. long, and 2 Mm. in width, when mature scurfy on the
furrows, their ridges being somewhat less prominent and colour
darker than the sweet variety.
1 2 345 6 7 S 9 10
A. — Fennel Fruits. — 1, German; 2, French (curved sweet) ; 3, Galician; 4r
Russian; 5, French (hitter); 6, Indian; 7, Japanese; 8, Persian; 9, French
(straight sweet). B.— Italian Anise Fruit.— (All drawings natural size.)
German. — The fruits (No. 1) are about 8 to 10 Mm. in length, 3 to
4 in width, ovoid-oblong, slightly curved, the five ridges, on each
mericarp very conspicuous, the lateral being distinctly the largest.
They are grown principally at Lutzen-W eissenfels, in Saxony,
and also in Thuringia ; and though partially discontinued some few*
years ago, the cultivation has been recently increased and com¬
petition entered into with Galician and Roumanian fruit.
Indian. — The fruits (No. 6) are usually more oblong and slightly
226
PHARMACEUTICAL JOURNAL.
[Mabch 13, 1897
shorter on the average than the French variety, being generally
from 6 to 7 Mm. long, straight, and browner in colour. Very large
shipments reach this country from Bombay, but the fruits are as a
rule much mixed with stalks, and very dry.
Russian. — The fruits (No. 4) are usually very clean and free from
stalks, etc., from 5 to 6 Mm. long, from 1| to 2 Mm. wide, and
the mericarps very easily detachable from one another. The colour
is usually brownish-green, the ridges very distinct. The fruits
imported from Roumania are practically the same as this variety.
Galician. — The fruits (No. 3) are very similar to the Russian and
Roumanian varieties, very clean, about 4 to 5 Mm. long, from 1 to
4 Mm. wide, the mericarps of the mature fruits easily detachable
from one another. The ridges are very prominent.
Persian. — The fruits (No. 8) when mature are about 6 to 7 Mm.
long, and less than 2 Mm. in width, straight, the ridges prominent,
and the colour very green. The particular shipment which has
been used for the distillation of oil contained a considerable number
of stalks and immature fruits, and was shipped to London from
Busheir, on the Persian Gulf. I am not aware that any previous
shipment has been made from Persia to London.
J apanese. — The fruits (No. 7) are very small, about the size of anise,
from 3 to 4 Mm. long and from 2 to 3 Mm. wide, ovoid, not curved,
and of a pale greenish-brown colour. They have no hairs such as
are characteristic of anise fruit. The shipment of those previously
reported on was made from Yokohoma, and considerable arrivals
have since taken place, all of which have been particularly clean
and free from stalks.
The odour and tastes of the fruits show certain differences, but
as they are entirely dependent on the essential oils, it will be
more convenient to refer to them subsequently after treating of
those bodies.
Microscopic Examination.
Microscopic examination of the transverse sections of the fruits
show the same general characters, viz. , that each mericarp has five
ridges, varying in prominence, some more obtuse than others, with
four vittse on the face and two usually on the commissure, although
occasionally as many as four, all surrounded by a brown tissue.
French (sweet). — Ridges very prominent, notably those at the
extremity of the commissure ; the vittse large, the length of each
being about *11 Mm., and the breadth about -04 to ‘05 Mm.
The pericarp varies from ’12 Mm. at the vittse to nearly three
times that thickness at the ridges.
Fennel Fruits, T. S.— 1, French (bitter); 2, Indian ; 3, Russian; 4, French
(•weet) ; 6, German ; 7, Japanese ; 8, Persian ; 9, Galician. 5, Italian Anise
Fruit, T.S. (Highly magnified).
French (bitter). — Mericarp much flattened, nearly twice as long
at the commissure as broad, the ridges at the commissure pointedly
prominent. The vittse six in number, arranged similarly to the
sweet variety, and about "2 to ’22 Mm. in length, and "07 to
•08 Mm. in width. The pericarp is somewhat thick.
German. — The section of the fruit shows prominent ridges, the
vittse frequently duplicated, seven or eight in number. They are
very large, varying from ‘2 to -22 Mm. long and about '07 to ‘08
Mm. broad. The pericarp is very evenly distributed round the
fruit, and about '2 Mm. in thickness.
Indian. — The length and breadth of the outline of each section
of mericarp is practically the same, the ridges less prominent
than in the French sweet variety and the vittse very small, only
about -1 in length and '04 in width, and in many hardly observable.
Russian. — The outline of the section of mericarp is oblong, the
length nearly double the breadth, as in the bitter French variety.
The pericarp, however, is very thin, and readily distinguishes the
two varieties. The ridges are not very prominent, the vittse about
•2 Mm. long, about '04 to ‘05 wide.
Galician. — The section shows that the mericarp is nearly twice
as long as broad, the ridges fairly prominent and the vittse very
long. They vary in length from '2 to ’22 Mm. and in width from
•08 to '10, the pericarp being even and of practically the same
breadth as the vittse.
Persian. — The section of the mericarp shows less curved surfaces
and the outline generally more angular than the other varieties,
none of the ridges being at all prominent. The vittse are six in
number, the size of each being about '15 Mm. long, -05 broad, and
the pericarp very regular and thick, about ‘2 Mm. even in the
thinnest portions.
Japanese. — The characters of the section differ from those of
most of the other varieties, most nearly approaching the bitter
French variety in outline, being oblong, the length considerably
more than the breadth. The ridges are not prominent, the vittse
on the commissure having length, '] 5 to T6 Mm., and breadth from
•07 to '08 Mm. , the others slightly smaller. The pericarp is very
regular, about T5 to "2 Mm. in width.
Essential Oils.
The proportion of oil in the different varieties varies very con¬
siderably, and follows very closely the size of the vittse, the highest
yield obtained being 4*7 per cent, from German fruits, the lowest
only ’35 per cent, from a sample of Indian fruits. These latter
were much contaminated with stalks, etc., and the yield was
equivalent to ’72 per cent, calculated on the fruits only present.
The low proportion of oil yielded by the Indian 'fruits makes
it quite clear why the aroma of this variety is comparatively so poor.
The principal characters of the essential oils, and those of the
features which are of the greatest importance, as bearing more
especially on the composition of the oils and consequently the
odour and taste of the fruits, are included in the second table.
Essential Oils.
Source.
Sp. gr.
Optical rotation
in a tube of
100 Mm.
Melting point
after
solidification.
Percentage
of
fenchone.
Anise . . .
•983 at 20° C.
- 1
15°'5 C.
None.
French Fennel (1) . .
•976 at 15° C.
+ 16-0
12-c’5 C.
None.
„ (2)
•980 „
+ 16-5
ll°-7 C.
• None.
Persian Fennel .
"977 ,,
+ 14
ll°-2 C.
3-4
Indian
•968 „
+ 21
8° ‘2 C.
6-7
J apanese
•975 ,,
+15-5
10°-0 C.
10-2
Saxon
•974 „
+22
6«'l C.
22-5
(1) l
•966 „
+22
4»-0 C.
19-3
Galician
” (2) j
■965 ,,
+ 20
6°-2 C.
18T
Russian
M .
•967 „
+ 23
4° -4 C.
18-2
Specific Gravity. — This varies between ‘965 and ‘980 at 15° C.
The specific gravity at 25° of anethol is *975, and the specific
gravity of those oils containing relatively the largest percentages
of anethol are the highest, one of the oils distilled from French
fruits having as high a specific gravity as '980 at 15° C. The
specific gravity at 19° C. of fenchone is -94fi.
March 13, 1897.]
PHARMACEUTICAL JOURNAL.
227
Optical Rotation. — From +6 to +22 in a tube of 100 Mm. This
difference is due principally to the variation in proportion of the
terpenes present, pinene, phellandrene. Anethol is inactive to
polarised light, whilst pure fenchone is very strongly dextro¬
rotatory.
Freezing Point. — This is principally influenced by the proportion
of anethol (m.p. 21°-22° C. ) present, but fenchone, when kept at a low
temperature, also solidifies to a mass of hard crystals, which re¬
melt at 6° C.
Fractionation indicates fairly clearly the relative proportions of
anethol (b.p. 234° C.), fenchone (b.p. 192-193° C.), and terpenes of
lower boiling point. The proportion boiling above 225° C. is
greatest in the oils distilled from French fruits, whilst the per¬
centage boiling below 220° C. is greatest in those containing the
most fenchone, viz., the Saxon, Russian, Galician, and Japanese.
Constituents. — The principal constituents of all the fennel oils
examined to which reference has been already made are the two
terpenes, pinene and phellandrene, and anethol and fenchone.
The two terpenes do not appear to affect the odour or taste of
the oils. Pinene is present in all the oils examined, and phellan¬
drene in appreciable quantity in the Indian and French varieties.
Variation in the relative proportions of the other two constituents?
however, causes the widest and most material difference, for whilst
the proportion of fenchone varies from 3 per cent, in the Persian
oil to over 18 per cent, in the Galician and Russian oils, in the
French oil it is practically absent.
Fenchone closely resembles its isomeride, camphor, having a
similar pungent odour, and naturally these varying percentages
make an immense difference in the pungency of the oil (and seeds),
and as it (fenchone) is reduced by sodium and alcohol to its
corresponding fenchyl alcohol, C10H17OH, the yield being quanti¬
tative, the proportion present is easily determined by this means
and estimation of the alcohol by the acetylation process. All the
oils examined contain anethol, most being present in the oils
distilled from French and Persian fruits, of which the high
melting point after solidification and the proportion boiling above
225° C. is evidence.
Having reviewed the characters of many of the commercial
varieties of fruits, one is better able to consider whether any real
reason exists for the confusion of some of the smaller varieties of
fennel fruits with anise fruits and also, which is more important,
to form an opinion as to the most suitable for pharmaceutical use.
F ord and Crow (Pharm. J ourn. [3], xviii. , 342) have pointed out that
Dr. Porter Smith was wrong in stating that the Chinese confound
the fruits of Pimpinella dnisum with those of Fcenicvlum capil-
laceum , as the umbelliferous aniseeds are not known in Hong Kong?
but the name that star anise has received (eight-cornered fennel)
indicates clearly that the similarity in odour between it and fennel
is duly recognised.
Dymock (‘Mat. Med. of W. India,’ 308) states that, according
to Mr. M. Sheriff, fennel and anise have been confounded together
in Arabic Persian works on materia medica, and although the
difference in the seeds is evident on careful scrutiny, the odour of
Persian fennel fruits is decidedly closer to anise than any of the
small varieties of fruits examined, the percentage of anethol being
very high and the fenchone comparatively low.
The oil from the French sweet fennel fruits is also very similar
to this variety, but the character of the fruits renders confusion of
them impossible. The oil possesses to a marked extent, in addi¬
tion, the same fatty odour which is present in oil of anise
{Pimpinella anisum ), and distinguishes it from the star anise oil
( Illicium anisatum).
The Indian fruits contain so little oil that their use is not
recommended, but in odour the oil appears to stand almost midway
between that of the Persian and Japanese fruits. It seems
probable that the hot climate has a detrimental effect on the
proportion of oil, and in consequence the odour of the fruits.
The oils of the Saxon, Galician, and Russian varieties vary
but little in pungency, and this is due to similar proportions of
fenchone, and slight differences only in the percentage of anethol
which they contain.
The Japanese fruits do not approach so nearly as French or
Persian to the odour of anise, although less pungent than the
Saxon, Galician, and Russian varieties, and it seems clear that the
misnaming of the fruits in the first instance was solely due, as I
originally stated, to their resemblance in point of size to anise.
Although several parcels of Japan fennels had previously been
offered at drug sales in London’asjanise, during the last few months,
the consignments have been correctly catalogued as fennel.
Reviewing, then, the results obtained, I am of opinion that the
Russian, Roumanian, Galician, Japanese and Saxon varieties are
best adapted for pharmaceutical use, with a preference
for the last named. In these fennels the percentage of oil is
greatest, the flavour more decidedly agreeable, and the fenchone
present is probably not without marked carminative properties.
These fruits answer all the characters as to size, etc. , of the drug
fennel as officially described both in the British and United State
Pharmacopoeias.
My thanks are due to my friend Mr. E. W. Lucas for the photo¬
graphs of the fruits and sections, and to my assistants, Messrs.
J. O. Braithwaite and R. S. Swinton, for help in the microscopical
and experimental portions of this paper respectively.
ON THE PRESERVATIVES OF PHARMACOPCEIAL
PREPARATIONS.
BY WILLIAM MARTIN DALE.
In the work of compiling formulas for the use of medical prac¬
titioners and pharmacists, care is necessary to test the keeping pro¬
perties of the various solutions and preparations, and having prepared
and kept a number of these preparations, I thought a few notes on
them might prove interesting. They are purely pharmaceutical,
and must not be considered as having bacteriological importance.
The vehicle mostly used for the internal administration of medi¬
cines, of course, is water in some form or other, but distilled water
alone is recognised by the Pharmacopoeia, and probably this, as
frequently met with, is more defective from a standard of purity
than most preparations in the Pharmacopoeia. It is even more
prone to develop minute organisms than many of the spring waters
that are to be met with, although these may contain inorganic
salts, which render them unsuitable as solvents and vehicles in
which to administer medicinal preparations. So much has distilled
water obtained this evil reputation that a bacteriologist of emin¬
ence is reported to have said that one of the best incubating fluids
was a certain manufacturer’s distilled water.
Various means have, therefore, been adopted for sterilising it
and rendering it aseptic for pharmaceutical use, such as keeping
it in a cool place, and of course free from dust, and having it
recently well boiled and cooled. The best and only method to be
depended upon, however, care having been taken to select a good
water for distillation, as well as to refuse the firsfc and last products,
and to ensure freedom from contamination afterwards, is to have
it freshly distilled ; in fact as regards the whole of the preparations
of the Pharmacopoeia, they should be as freshly prepared as
possible, and the use of preservatives should be avoided unless
absolutely necessary, but from a practical point of view we cannot
228
PHARMACEUTICAL JOURNAL.
[Maech 13, 1897
do without them. For example, the public demand for pills is
now that they must be well preserved and look nice, although they
may be nsoluble.
Alcohol. — The most common preservative used officially is alcohol
•in one form or another ; it is true it is not used solely as a preserva¬
tive but as a solvent ; it enters more or less into the composition
of nearly all our tinctures, liquid extracts, wines, and many of our
official solutions. The germination of most of the micro-organisms
■occurring in aqueous solutions of vegetable and animal substances
is inhibited by the presence of 20 per cent, by volume of absolute
alcohol, but it is inhibitory only, and in this proportion or upwards;
it is in no way germicidal, as on evaporation the ancesthetised
germs, if I may so term them, readily take up life and propagate.
This applies to most of the volatile antiseptics, in fact, few
antiseptics are germicidal except those that are destructive to
organic tissues, such as strong mineral acids, alkalies, and
halogens. Exceptions to this are cai’bolic acid, creasote, and
weak solutions of corrosive sublimate, which act probably by
-coagulating the albuminous substance of the microbe. Wines I
have mentioned ; unless fortified, from their very origin, that of
fermentation, they are too weak to prove of useful service in
pharmacy, and in fact medical wines are anachronisms.
Glycerin. — The abuse of alcohol has led those who take extreme
views on this subject to endeavour to use other solvents and pre
servatives for pharmaceutical preparations. Among these, avoiding
•-ethylic alcohol, whose physiological properties are too well known, *
they have selected glycerin, which is but another alcohol whose
•action physiologically is not so well ascertained, nor is it so
inhibitory to. the development of micro-organisms. Its strong
solvent action on vegetable extractives, its non-volatility, and its
stability in other respects would have rendered glycerin a usefu
pharmacopceial solvent, but although it has been tried again and
again and was made official, more especially in preparing some o
the liquid extracts of the United States Pharmacopoeia, it has
not met with general acceptance. It nevertheless has a curious
preservative action over some inorganic compounds in preventing
oxidation. For example, black mercurial lotion can be preserved
in its normal black colour by the addition of 5 per cent, by volume
of glycerin, but I find that 10 per cent, of mucilage of tragacanth
will produce the same result, and have the advantage, from its
viscosity, of holding the mercurous oxide well suspended; the
addition of both these to this preparation would be an advan¬
tage. It has further been suggested that glycerin should be
used to preserve sublimate solution, especially the official
liquor hydrargyri perchloridi, as it has been thought necessary
that this solution requires presei’ving, from the chemical, not,
of course, from the biological point of view. But both glycerin
•and alcohol added to this solution, especially if exposed to light,
■cause a reduction of the salt and deposition of mercurous chloride,
as in the official solution of the Codex, which contains 10 per cent,
of alcohol. Notwithstanding statements to the contrary, I find
that a simple solution of mercuric chloride in distilled water, or
even in spring waters containing supercarbonate of lime in solu¬
tion, is more stable than it is with a preservative added, especially
one of such a nature as chloride of ammonium in the official solu¬
tion. This, as I showed so long ago as 1870,* instead of being a
preservative, forms a double salt in solution (sal alembroth plus
an excess of chloride of ammonium), and the solution, if
prepared with common water in place of distilled water,
or even if prepared with distilled water and diluted, throws down
a quantity of one of the white precipitates of mercury. To such
an extent is this the case that I found in preparing a pint of the
official solution with New River water in place of distilled water,
that 2-7 grains of this precipitate was deposited, thus about one-
fourth of the mercurial salt was rendered insoluble in preparing
the solution, and more deposited on further dilution with the
water. In fact, a time arrived when there was scarcely a trace of
mercury salt in solution, and as this preparation is most largely
used in hospitals where common water is always used to dilute
the medicines, it leads to very discrepant results therapeutically.
It has also been suggested that chloride of sodium should replace
chloride of ammonium in the official solution, as this salt
is largely used in making the sublimate tablets for the
convenience of surgeons’ use, but I have found that although
sodium chloride helps these tablets to disintegrate readily it
has no advantage, in fact it is detrimental to the keeping
properties of the solution. I have here two specimens prepared
in November, 1895, with water from the Brighton constant
supply, which is a very calcareous water ; one is a simple solution
of the perchloride, and the other has an equal weight of pure
chloride of sodium added. The latter you will observe has deposited
much more than the former, in which there is hardly a trace of
deposit. This strongly illustrates the undesirability of tampering
with solutions in order to make them, as we consider, more stable,
in fact, with few exceptions no preservative should be added to
a pharmacopceial preparation unless the label indicates boldly that
it is there. While on the subject of mercuric salts, I should like
to illustrate the importance of having our lime water of full
strength, and well preserved.
In making the yellow mercurial lotion of the B.P., which has
18 grains of sublimate to 10 ounces of lime water ; if the lime
water be only three-fourths, or from keeping, so low as one-half the
pharmacopoeial strength, a brick-red preparation, an oxychloride,
is produced, rather than the yellow mercuric oxide.
Acetic Acid. — Of other preservatives, which are also solvents used
officially, acetic acid of varying strengths is employed, as in acetum
cantharidis and acetum scillse. This, as I notice Professor
Remington recently points out,* was much employed in the
pharmacy of the ancients, sometimes combined with honey to form
oxymels, of which we have inherited both the vinegar and oxymel
of squill. Acetic acid has the disadvantage, however, unless in a
very concentrated form, of growing micro-organisms abundantly,
and the fungi and animalcuke developed in brown vinegar must be
well known to all of you. Acetic acid, therefore, besides being
incompatible with alkalies, is not a good preservative, although in
some cases it may be a useful solvent.
Sugar. — Of the preservatives used officially which are not solvents,
this is employed most extensively, not only with us, but in
France and in the United States ; in fact, so much is this the
case in France, that Mr. Ince once remarked in this room that
French pharmacy might be summed up in the one word, “ sugar.”
On account of its palatability it of course meets with favour, espe¬
cially among children. It enters into the composition of all the
syrups and lozenges, and most of the confections and powders, and
is a useful preservative from oxidation of the ferrous preparations,
such as the saccharated carbonate of iron, mixture of iron, Blaud’s
pill, and iodide of iron pill. It also preserves lime in solution, as
in the well-known liquor calcis saccharatus, of a strength about
sixteen times that of the official lime water ; if a pure marble lime
be used, I find as much as 1 ‘77 per cent, is dissolved, or 8 T6 grains
in a fluid ounce. This preparation is more conveniently made by
using an equivalent weight of syrup, i. e. , three ounces in place of
two of sugar, and adding it to nineteen ounces of distilled water
* Pharmaceutical Journal [2], vol. xi., p. 544.
American Journal of Pharmacy, March, 18P7, p. 121.
Makch 13, 1897]
PHARMACEUTICAL JOURNAL.
229
containing the lime in suspension. The “caking” which is apt
to occur is thus avoided.
Salicylic Acid. — The well-known uses antiseptically of this for
surgical purposes, although prohibited from being used for pre¬
serving wines in France, have rendered it serviceable in preserving
the official solution of hydrochlorate of cocaine, which contains
1J per mille of the acid, with 10 per cent, of the cocaine salt. I
find that this solution, even if diluted with four times its volume
of water, still keeps free from fungoid growths. The use of this
acid might be objected to in the solution, because salicylic acid
forms with cocaine an indefinite compound rather than a salt, the
so-called salicylate of cocaine ; but it appears not to throw the
hydrochloric acid out of combination, and has proved very service¬
able in preserving the solution of this cocaine salt, which has a great
tendency to develop fungoid growths. The salicylic compound
appears to be allied to the benzoic compound, benzoyl-ecgonine.
It forms a pasty mass which has not, that I am aware of, been
studied. If any defence were needed for using a preservative,
perhaps this official solution of cocaine is 3, typical case. The use
of this solution of salicylic acid, per mille, which is nearly
saturated, as a vehicle, might be extended to other solutions, for
example, the official solution of sulphate of atropine, but I have not
found this solution, if made with a well-crystallised salt, prone to
grow fungi. Its use, however, cannot be extended to the hypo¬
dermic injection of morphine ; if a solution of tartrate of morphine,
1 in 12, or even 1 in 20, be prepared in it, a crystallised salicylate
of morphine separates. 16£ tartrate keeps well alone.
Of the salts of morphine suitable for hypodermic injection, the
tartrate seems to be now favoured ; the acetate solution, prepared
by dissolving pure morphine in just enough acetic acid, has till
lately been mostly used, but it has the objection of possessing a
tendency to decomposition and becoming muddy and dark-
coloured. Still I have two solutions here over 18 years old, no
extra sterilising precautions were taken when made ; they are
well preserved and are perfectly transparent, although they have
slightly changed colour. One is of the strength of 1 grain in
6 minims, which I advocated in a paper in 1870,* the other is
1 grain in 12 minims. A small dose is generally preferred for
hypodermic injection, but the strength of 1 grain in 6 minims is
considered now to be dangerously strong in the hands of an un¬
skilled operator. The more nearly saturated, however, the
aqueous solution of any salt or crystalline principle is, the better
it will keep ; in fact, it was a curious argument of an advocate for
spontaneous generation that there was a debatable land between
that of crystallisation and the germination of organisms in these
solutions — that is, between the growth of crystals and of
organisms ; this applies widely in pharmacy, as we well know,
in keeping syrups for example. A nearly perfect syrup consists
of two parts of sugar and one of distilled water ; kept at a uniform
temperate heat, this neither crystallises nor grows fungi ; and our
solid medicinal extracts are preserved if they contain no excess of
moisture.
Further, these remarks especially apply to the official solutions
of acetate and citrate of ammonium, which are much better kept
in a concentrated form.
The salicylic acid solution cannot either be used for preparing
the hypodermic injection of aponforphine ; a 1 per cent, solution
of the hydrochlorate of apomorphine prepared in it gives a
quantity of a crystalline deposit.
Hydrochlorate of apomorphine in aqueous solution rapidly
develops a green colour ; this has been attributed to the influence
of ammonia in the atmosphere, but although a drop of solution of
* Pharmaceutical Journal [2], vol. xi., p. 480.
ammonia does develop the green colour immediately, it is
apparently not due to this alone. This salt is now prepared much
purer than formerly, and it is also not so soluble. The official
strength of the hypodermic injection, 1 grain in 50 minims, i.e., 1
in 45 ’5 parts, of camphor water is not held in solution at 60° F.
Dott gives the solubility in water as 1 in 50 '89, Squire as 1 in 56 to 60.
I find 1 part in 60 of boiled and cooled distilled water dissolves, but
turns green within a few hours, but if acidulated with a trace of
hydrochloric acid, say an equal weight of the official diluted
hydrochloric acid, the colour is preserved, but it is rendered less
soluble. More than a 1 per cent, solution, if acidulated, is not
certain to keep free from crystals at the variable temperatures to
which it may be exposed, and less than the quantity of acid I
have named does not keep it free from colour.
Sulphurous Acid. — A trace of sulphurous acid, say one-quarter
per cent., added to a 2 per cent, solution of the apomorphine salt
keeps the solution for a moderate time, but not indefinitely, and
the use of such a deoxidising agent is not desirable, as its action
on the apomorphine salt is not clearly understood. Nevertheless,
sulphurous acid is largely used as a preservative of such prepara¬
tions as orange wine.
Boric Acid. — Of the preservatives suggested for keeping
apomorphine injection, boric acid has been mentioned, but this I
find, in a solution containing 2 per cent, of each, boric acid and
hydrochlorate of apomorphine, forms an opaque white jelly, and
even with 1 per cent, of each a curious translucent jelly is formed,
quite unsuitable for hypodermic injection. Boric acid has been
recommended and is used largely for preserving solutions for
hypodermic injection, but as a solution of it, 1 in 30 parts of water,
which is nearly saturated, will itself develop some peculiar fungi,
I can see little advantage in employing such a preservative
pharmaceutically. Mr. Lee has mounted a specimen of a torula
which has been grown in a saturated solution of boric acid in
distilled water.
Camphor Water. — The same remarks apply to camphor water,
the favourite of Raspail, as to boric acid. It is a weak inhibitor,
and it further has the disadvantage of the camphor being volatile.
Camphor water is official as the solvent of atropine in the solution
of sulphate of atropine, but oculists complain of the irritating
action of camphor on the eye.
Chloroform. — The addition of chloroform to vegetable infusions
and other aqueous preparations of vegetable and animal sub¬
stances was recommended by Mr. J. B. Barnes* in the proportion
of from one-eighth to one-half per cent, by volume. The addition
of chloroform as an inhibitory in suspended pharmaceutical opera¬
tions is of great service, and it has the advantage that by gently
warming the solution for a short time it can be easily dissipated,
but it has also the disadvantage that the chloroform evaporates too
easily for prolonged preservation, yet I have tried the experiment
of preserving fruit (damsons) in stoppered bottles, adding [about
one three-hundredth part of their weight of chloroform to them.
The preservation was complete, but the flavour of the chloroform
was not dissipated by even baking the fruit in pies.
Hydrate of Chloral has been used as possessing similar properties
to chloroform, being more readily soluble and less volatile, but its
taste is nauseous.
Carbolic Acid. — The odour and flavour of this most powerful
antiseptic is against its use for internal administration, excepting
for hypodermic injections ; it is the best preservative of ergo tin in
aqueous solution. Boric acid in this solution fails ; Mr. Severn
kindly infected for me three solutions of ergotin with Penicillium
glaucum ; No. 1, without preservative added, developed in forty*
* Pharmaceutical Journal [3], voL v., p. 441
230
PHARMACEUTICAL JOURNAL.
[March 1?, 1897
eight hours ; No. 2, with 1 per cent, of phenol added* is un¬
developed yet, after five days ; No. 3, with 2 per cent, of boric
acid, developed on the side of the bottle, just above the surface of
the liquid, in seventy-two hours. Creosote also, although one of
the best preservatives, as its name indicates, is not admissible,
on account of its odour.
Cherry Laurel Water. — This is recommended in France for pre¬
serving hypodermic injections. So, also, are the distilled waters
of meadow sweet and eucalyptus. I am not aware that
Formaldehyde has been much used pharmaceutically, although it
has, I understand, been used for milk preserving for some time.
Its peculiar action on gelatin in rendering it insoluble would tend
to prove that it was not desirable for internal administration, as it
might seriously interfere with digestion.
Hypophosphorous Acid. — This and citric acid are employed
commercially to prevent the change of colour of the ferrous
syrups ; as traces only are needed, it may be considered a venial
offence. But preservatives are sometimes used, or are added even
officially, which are often disadvantageous. For example we have
two arsenical solutions official, one acid and the other alkaline. A
simple solution of arsenious anhydride in water of the same
strength, coloured if desired, is perfectly stable. It would be com¬
patible with both acids and alkalies, and might take the place of
both the official solutions.
Carbonic Acid. — This in solution in water is inhibitory to organic
growths, and is largely used in preparing carbonated waters and
“Fluid Magnesia,” but otherwise it is not of much service.
Benzoic Acid. — For preserving lard and some official ointments
the melted fats are macerated with powdered benzoin, by which
means they obtain an agreeable odour and become impregnated
with benzoic acid. Both these tend to preserve the fats from
becoming rancid. But in using these fats for preparing the oint¬
ments of the alkaloids, apparently some change takes place ; they
become discoloured, and in the case of cocaine we know, as I have
before mentioned, a comparatively inert compound of benzoyl-
ecgonine, etc. , is formed, so that the use of benzoated lard is to be
avoided for preparing these ointments.
Paraffin Basis. — Where quick absorption is not required, the
preservative action of the soft paraffins renders them all that can
be desired, as also is oil of theobroma for suppositories.
Aromatic Waters and Essential Oils.- — The oils of clove, cinnamon,
peppermint, and many others are preservatives ; so are their
aqueous solutions, but I can only mention them.
Heat and Cold. — A gentle heat assists the incubation of nearly all
micro-organisms ; a greater heat, that of boiling water for example, is
a steriliser ; whereas a still higher temperature is a disorganiser,
and is destructive to all organic growths. Cold, on the contrary,
the freezing point of water and below, as a rule, is only inhibitory
to the development of the lower organisms, their vitality is but sus¬
pended, and they spring into life again with the first application
of a gentle warmth. It may appear irrelevant to my subject, but
the important bearing preservatives haveon our food supplies, includ¬
ing frozen meat, makes them of great importance commercially. In
fact, in viewing the pharmaceutical aspect of preservatives, I have
but touched the fringe of the subject of their utility. Without
the aid of boric acid and other preservatives, many of our articles
of daily food would be at famine prices. In such a condensed
population as that of London, it would now be almost impossible
to supply the necessary quantities of butter, milk and fish in a
fresh condition. We have long been dependent to a great extent
on the importation of flour and corn. The same has now become
the case in regard to our animal food products.
PRACTICAL PHARMACOGRAPHY.
STRUCTURAL CHARACTERISTICS OF SOIRE IMPORTANT DRUCS
AC n NIT I RADIX.
Aconite Root.— Eacine d’Aconit. — Sturmhutwurzel.
The Powder of this
Dill Fruit. — Fr. Fruits d’Aneth. — Ger. Dillenfriichte.
Macroscopic Characters. — The dried fruits of Peucedanum graveo-
lenSy as met with in commerce, may be of British or Indian origin,
but preference should be given to the former, since there is a
difference in the oil yielded by the two fruits. The British variety
(Fig. II. , A) consists mostly of the separate brown meri carps, which
are oval in shape and have five equidistant filiform ridges. Of
A1 A2 B1 B2 C
Fig. II. — Anethi Fructus. — A, British fruit (nat. size) ; Al, convex side of rneri-
carp (magnified) ; A2, flat side of mericarp (magnified) ; B, Indian fruit (nat. size);
Bl, convex side of mericarp (magnified) ; B2, flat siue of mericarp (magnified) ;
C, transverse section through mericarp (magnified).
the latter, three are prominent at the back and the other two are
merged in the broad thin margin or wing. Indian dill (Fig. II., B)
is more elliptical in form than British, more convex at the back,
and looks narrower and longer, but in reality there is very little
difference in size between the two varieties. The Indian fruits are
often stalked, however, and their mericarps are united. In
colour also they are paler than the British fruits when seen in
bulk, whilst their taste is rather more pungent. On an average, dill
fruits are about 3 to 4 Mm, long and 2 to 3 Mm. broad.
Microscopic Characters. — The pericarp of the fruit (Fig. III.} con¬
sists of thin-walled, tabular, tangentially-elongated cells, those in
March 13, 1897]
PHARMACEUTICAL JOURNAL.
231
the outer rows being small and colourless. The inner rows con¬
sist of larger cells, which are brown in colour, especially those
near the vittse or oil receptacles. The endocarp is a single
VB
Fig. III. Anethi Fructus. — Transverse section of mericarp. V vitta ; VB,
vascular bundle ; E, endocarp ; End, endosperm, (x Abt. 60.) After Berg.
row of tangentially-elongated, yellowish cells, which are very
regularly arranged and rectangular in transverse section.
Through each’] ridge runs a strong vascular bundle, and large
vittse alternate with the ridges, whilst two occur on the flat
surface or commissure of each mericarp. The endosperm consists
of somewhat thick-walled, polygonal cells, which contain oil and
granular proteid matter.
ANISI FRUCTUS.
Anise Fruit.— Fr. Fruits d’Anis vert.— Ger. Anis.
Fig. IV. Anisi Fructus.
— A, Russian, B, Maltese,
(nat. size) ; C, magnified ;
D, do. longitudinal section.
Fig. V. Anisi Fructus.
Transverse section
Macroscopic Characters.— There are several
commercial varieties of the dried fruits of
Pimpinella anisum — Maltese, Alicant, Ger¬
man, Russian, and Chilian— differing from
each other in size, colour, flavour, and rela¬
tive freedom from impurity. The Maltese
and Alicant fruits are larger than the others,
and leave a more acrid and bitter after-taste.
The first-mentioned is
brownish-green and the
second yellowish -green in
colour, whilst the German
and Russian are greyish-
green. The Chilian fruits
are mixed with much foreign matter, so that
their colour is not readily discernible, and the
mericarps are generally separated more or
less. The average size of anisi fruits is about
5 Mm. long and 2 Mm. broad. They are
mostly undivided and attached to a slender
pedicel, ovoid in form, and covered with
minute, simple, erect, somewhat adpressed i r ch'Vud
hairs (Fig. V.). Each mericarp is marked by oesterle.
five ridges, two of which are lateral.
Microscopic Characters. — The structure of anise fruit resembles
that of dill and other umbelliferous fruits, but the numerous short,
cone-shaped hairs
developed from
the epidermal
layer are very
characteristic, as
are also the un¬
usually numerous
vittas (Figs. V.
and VI. ). Of
these there are
sixteen to thirty
in each mericarp,
the largest oc-
Fig. VI. Anisi Fructus.— Transverse section of meri curring in the
carp. V, vitta ; VB, vascular bundle ; E, endocarp ; End> commissure. A
endosperm, (x Abt. 50.) After Tschirch and Oesterle. further "note¬
worthy peculiarity is the thickening of the seed-coat at the com¬
missure.
The Powder is greenish-brown, with characteristic odour and
taste. In it may be distinguished (Fig. VII. ) the short, conical,
unicellular hairs, either isolated or attached to fragments of
the epidermal layer ; fragments of the parenchyma, scleren-
chymatous cells, and portions of vascular bundles from the
pericarp ; and small pieces of the seed-coat and endosperm,
together with cluster crystals of« calcium oxalate and aleurone
grains from the cells of the latter. Traces of the vittse appear
in small particles and, even in fine powder, fragments may some-
Fig. VII. Anisi Fructus. — 1. Transverse section through pericarp and seed-
coat ; ep, epidermis ; o, vitta ; en, endodermis. 2. Portion of epidermis, showing
hairs and stoma. 3. Two layers of parenchyma from seed-coat. 4. Vittte, as seen
in longitudinal section, (x Abt. 160.) After Moeiler.
times be found in which two or more of these oil receptacles are
united, as shown in the illustration.
ANISI STELLATI FRUCTUS*
Star Anise Fruit.— Fr. Anis Etoile. — Ger. Sternanis.
Macroscopic Characters.- — The fruit of Ulicium verum is about
3 to 4 Cm. in diameter, and consists of eight follicles or carpels,
each of which ends in a straight point and contains a single seed.
A C
Fig. VIII. Anisi Stellati Fructus. — A, back ; B, Front ; C, curved stalk ;
D, carpel. (All natural size.)
These follicles are arranged horizontally on a curved footstalk or
peduncle, and touch each other only at the inner margin. They are
slightly open, showing the dark brown seeds within (Fig. VIII.).
The fruits of Illicium religiosum, which are poisonous, are only about
232
PHARMACEUTICAL JOURNAL.
[Mabch 13, 1897
Cm. in diameter, and the tips of their carpels are incurved, whilst
the stalks are not curved. The seeds in this species are yellowish-
A D B C
Fig. IX. — Anisi Stellati Fructus (false). — A, back ; B, front ; C, straight
stalk ; D, carpel. (All natural size.)
brown and more exposed than in Illicium verum, owing to the carpels
being more widely open than in the latter species (cf. Figs. VIII.
and IX. ). They do not possess any anise odour.
Microscopic Characters. — A transverse section through a carpel
(Figs. X. and XI.) shows a compact outer coat of irregularly
S B
polygonal, tabular cells with sto¬
mata, and inside this a layer of
loose brown parenchyma, which is
strongly developed at the back of
the carpel. In this tissue are found
vascular bundles, large oil cells, and
curiously shaped sclerotic cells or
idioblasts, which also occur plenti-
' * fully in the fruit stalks. Along the
Fig. .X.— -Anisi Stellati Fructus. ventral suture the parenchyma is
sclerotod, and the smooth
S, stone cells lining inner walls ; B, inner walls of the carpel near the
bast cells (magnified). After Tscbirch opening are lined with closely -
and Oesterle. fitting, almost cubical cells. The
cavity of the carpel occupied by the seed is lined with palisade
tissue. Similar b.ut more strongly thickened palisade cells
occur in the outer layer of the seed-coat, and under this tissue lies
a single layer of cells thickened on one side. Next in order,
proceeding inwards, come the spongy parenchyma and the
inner layer of the seed-coat, the latter containing crystals
of calcium oxalate. The upper layers of spongy paren¬
chyma are irregular and peculiarly sclerotised. The endosperm
consists of soft-celled, oily parenchyma, which contains no starch.
1
2
VB
3
4
Fig. XI. — Anisi Stellati Fructus. — Section through wall of carpel. O, oil-cell ;
VB, vascular bundles ; 1, epidermal layer ; 2, parenchyma, containing oil-cells ;
3, schlerenchymatous cells ; 4, ditto lining inner wall ; 5, layer of palisade cells,
lining seed cavity. (Highly magnified.) After Tschirch and Oesterle.
The Powder is yellowish-brown, with characteristic odour and
taste. The bulk of it consists of the reddish-brown parenchyma
of the carpels and the colourless fragments of the sclerenchymatous
elements, including different kinds of stone cells — cubical and
staff-shaped stone cells from the inner lining of the carpels, sclero¬
tised parenchyma, stone cells from the seed-coat, and finally
detached sclerotic cells or idioblasts from the stalks. In very fine
powder these different kinds of schlerenchymatous cells, on account
of their size, are seldom found whole. The prettily marked,
wavy thickenings of the cuticle (Fig. XII,, 1) covering the
carpels is characteristic, as are also the spongy parenchyma of
the seed-coat and the prismatic crystals of the: inner seed-coat
(Fig. XII., 9 and 11).
Fig. XII. — Anisi Stellati Fructus. — 1. Epidermis. 2. Palisade tissue lining
cavity of carpel. 3. Stone cells lining walls of carpel near opening. 4. Ditto
viewed longitudinally. 5. Parenchyma, transverse section. 6. Ditto, viewed
longitudinally. 7. Schlerenchymatous tissue from seed-coat. 8. Ditto viewed
transversely. 9. Spongy parenchyma of seed-coat. 10. Palisade tissue of seed-
coat, viewed from above. 11. Inner layer of seed-coat, showing prismatic
crystals. 12. Endosperm. 13. Sclerotic cell or idioblast from fruit stalk, (x Abt.
160.) After Moeller. _
PHARMACEUTICAL SOCIETY
EVENING MEETING IN LONDON.
At the evening meeting of the Society, held on Tuesday, the 9th
inst. , the President, Mr. Walter Hills, took the chair at 8 o’clock.
The first paper read was on —
The Commercial Varieties of Fennel and their Essential Oils,
by Mr. John C. Umney. The paper is printed at page 225, and
gave rise to the following discussion : —
The President said he had referred to Hanbury’s ‘ Pharmaco-
graphia’ to see what fennel was used for, but as far as he could see it
was only employed for compound liquorice powder ; he should be glad
to know if it was used in any other way in this country. Of
course, it was used in veterinary practice and in the manufacture
of cordials. Seeing that compound liquorice powder was now so
largely used, it was important to see that the fennel used had a
due proportion of the essential oil, and it was interesting to note
that that proportion seemed to vary with the size and number of
the vittae.
Mr. Chas. Umney said this paper showed clearly that wholesale
druggists had been in the habit of buying the very worst kind of
fennel seeds, for at the last auction he saw a ton of the East Indian
variety sold, and they were thought rather good, though it was now
Maech 13. 1897]
PHARMACEUTICAL JOURNAL.
233
evident that they contained the smallest proportion of essential
oil. Probably hot climates, such as that of India and Persia, were
not so well suited to the plant as a more northern latitude. He
recently saw a large quantity of seed sold which came from the
Black Sea, probably from South Austria or Russia ; they were very
small, and until quite lately passed under the name of anise in the
catalogues. Seeing that the specific gravity varied as much as
from 9-80 to 9-63, it was evident that the tests for the oil could not
be quite so exact as one would like. The optical characters also
seemed to vary considerably, and it was remarkable that while the
Persian only rotated 14°, the Indian rotated 20°. During the last
few years the consumption of fennel seeds in this country had been
enormous, and this paper gave very valuable data to those who
wished to study the subject further.
Mr. Holmes said they were much indebted to Mr. Umney for
this paper, which contained one or two points of practical
importance, especially in view of the new pharmacopoeia. So far as
one could judge from the figures given, if anethol were desired to be
given, oil of anise should be used, but if something different were
required, an oil containing a large proportion of fenchone should
be employed. The sweet French oil appeared to contain prac¬
tically no fenchone, but nearly all anethol. The Saxon, Russian, and
Galician oils appeared to contain approximately the same percentage
of fenchone and anethol, and the highest percentage of essential
oil, and seemed best adapted for use in medicine. There were
also interesting botanical questions arising out of this subject.
On the table there were specimens of the large fruited sweet
Bologna fennel, Foenicidum piperitum, and the bitter French
fennel, and also the Fceniculum vulgare which was cultivated
in this country. These were all different in the character and
outline of the leaf ; but the plants Mr. Braithwaite had grown
from Japanese seed corresponded much more nearly with the
F. piperitum than with the large sweet fennel. Botanists knew
that the fennel which was often found growing wild near the sea
was very different in leaf to that which was cultivated, the seg¬
ments of the leaves being shorter and more succulent, and it was
evident, therefore, that the plant was very variable. These
differences were not, he thought, sufficiently attended to. So far
as he could gather from the specimens under the microscopes,
there were two main groups, one the Japanese, which had several
rows of oil-secreting cells (?) round the vittse, whilst in the bitter
French there were two or three rows, and in the Saxon two,
whilst in the others there appeared to be only one row. This
was a difference in structure which seemed almost to indi¬
cate a distinct species. The Saxon seemed almost like a
hybrid between the ordinary fennel and the F. piperitum, but how
far further investigation would show that to be the case he could
not say. The Japanese seemed to occupy a somewhat anomalous
position, it contained 10 per cent, of fenchone, and its melting
point was 10° C., indicating that there was a large amount of
anethol, and would therefore have a strong taste of anise, which,
taken in conjunction with its small size, would account for its
coming into commerce under that name.
Mr. Martindale said the flavour of anise and fennel oil was of
very great service in aromatic waters, especially with children, being
sweet and not pungent. That was probably due to the absence of
fenchone and the presence of anethol.
Mr. Braithwaite said the Japanese fennel exhibited was from seed
sown last year ; it was now beginning to throw up a flowering stem
and it would probably flower in June. He had several plants of the
same growth under shelter, and fifty or sixty in the open, which
naturally were not so forward. The shape of the leaf in the seed¬
lings when they first germinated was more like that of a carrot than
ordinary fennel. At any rate there was none of that filiform leaf
which characterised garden fennel, but these plants were as yet
only in an immature state, and one could hardly tell what they would
look like when they grew older. When he first examined the Japanese
fennel seeds under the microscope he was pleased to find they were
different to any others he had then seen, but he had since found that
the bitter French variety was almost identical, though he did not pro¬
fess to be a microscopist. Still, it seemed to him that the vittse were
constructed on the same lines : In each the secreting cells extended on
either side, forming a more or less continuous ring surrounding
the inner integuments. The Saxon fennel, also, showed a some¬
what similar structure, but there the cells formed a uniform ring
round the vittse, whilst in the Japanese and bitter French these
cells all ran towards the margin of the seed, or nearly so. He
had been looking up the subject, and found that hardly any two
descriptions agreed, so that it appeared as if plants cultivated
in different localities varied greatly in their characteristics. This
was quite borne out by the present paper, and it would appear that
fennel was partly subject to the influence of soil and climate, as was
the case with many of the Umbelliferse. Another point in which
the Japanese and bitter French fennels agreed and differed from
the sweet fennel and the Saxon was the appearance of the costse or
ridges. This paper showed in a vivid manner what interesting
subjects cropped up in the London drug market, and the advantage
of keeping a sharp eye on what happened there. The whole thing
had arisen from the fact of Japanese fennel being introduced
under the name of anise seed, though it did not require very
great skill to distinguish them, and it was quite evident that Mr.
Chas. Umney had not forgotten what he learned in that school
about materia medica, or as it was now called, pharmacognosy.
Mr. Lucas said it was quite evident that the Indian variety of
fennel ought not to be admitted into the Pharmacopoeia, and he
would ask Mr. J. C. Umney if there were any other way of excluding
it than by the size of the vittse, which were very small, about one-
quarter that of any of the other varieties.
Professor Greenish said it was a great pleasure to listen to a
paper which dealt with the histology of a drug, as well as its
chemistry. He would point out that the measurements of the
vittse given in the table referred only to the breadth and length of
the transverse section, but it was quite easy to isolate the vittse
from the fruit, when it would be found that they
were of an elongated form, tapering at each end, and
thus it followed that the size in the transverse section
would vary with the point at which the section was taken.
It would be well, therefore, to note in the table that the section
should be taken at some particular point in the fruit. Another
point well worth consideration in dealing with drugs of any kind —
bark, seeds, or fruit — was the difference found in different speci¬
mens taken not from one parcel, but from different parcels. He
had examined many different fennel seeds, Saxon, Indian, French,
and Japanese, and as far as he could remember, his results agreed
very fairly with those obtained by Mr. Umney. A remark had
been made that in some seeds there appeared to be several rows of
secreting cells surrounding the vittse, in which the oil was pro¬
duced. As a matter of fact, these vittse were surrounded
in their younger stages by only one row of secreting cells, and the
oil was secreted, not in the cell itself, but in the wall of the cell
which bordered on the cavity, so that there would not appear to
be any possibility of more than one row of secreting cells. The
appearance of two or three rows was probably produced by the
section assuming an oblique direction, giving a view under the
microscope of several cells, which were not really one behind the
other, but one above the other in the fruit. After the oil had been
discharged the cells collapsed and became infiltrated with a brown
substance, called vittine, which made the cell less conspicuous
even than before. The only way to ascertain whether the
Japanese fennel did really form more than one row of secreting cells
would be to examine the fruit in the younger stages of growth.
Dr. Attfield said it might be taken for granted that any new facts
which Mr. Umney had brought forward would be carefully con¬
sidered by the compilers of the Pharmacopoeia. He should like to
ask whether the seeds and oils examined represented the growths
of various years as well as of various countries.
Mr. J. C. 'Umney, in reply, said the only use of fennel in this
country, so far as he had ascertained, was for compound liquorice
powder. On the Continent it was used largely for liqueurs. The
difference in the rotatory power of the Persian and Indian oils was
due to the fact there was more anethol in the Persian,
and that having no rotatory power it lessened the rota¬
tion of the oil. As had been remarked by Mr. Holmes, there
was a large percentage of anethol in the Japanese fennel oil ; as
far as could be ascertained by fractionation. Some showed as much
as 75 per cent. , whilst in some of the Galician and Roumelian it
was as low as 62 or 65 per cent. Professor Greenish had remarked
on the difficulty of cutting sections at the same level in the fruit.
Of course this was an important point, but as far as possible fully
grown fruits had been selected, and the sections taken from the
middle, in order that the sizes might be as nearly as possible com¬
parable. The only two opportunities he had had of distilling the
oil from different seasons’ fruits were in the case of two Galician
and two French samples. In the former case the results were
remarkably similar, and in the latter not widely different.
The President, in moving a vote of thanks to Mr. Umney, re¬
marked that if Indian fennel did not yield sufficient oil there were
other parts of the Empire — on which the sun never set — in which it
234
PHARMACEUTICAL JOURNAL.
j March 13, 1897
could be grown with a sufficient percentage, even if the demand
for compound liquorice powder should become still greater. He
would include in the vote of thanks Mr. Lucas, who had prepared
the microscopic sections, and Professor Greenish who had shown the
lantern slides.
The next paper was read by Mr. William Martindale, and
consisted of
Notes on the Preservatives of Pharmacopceial Preparations.
It is printed at page 227, and gave rise to the following
discussion : —
The President said the subject was so large as to be rather
difficult to comment upon, and he must confess that in the result
he felt somewhat bewildered as to what method could be relied
upon except either heat, or cold, or absolute purity.
Mr. Ince said the ideas now prevalent with regard to the pre¬
servation of medicinal preparations were very different to those
formerly current. For instance, with regard to distilled water, the
plan adopted for years and years, especially in the case of aromatic
waters, was to add a little alcohol. That had now been discarded,
as it was found to be one of the best ways of promoting decomposi¬
tion, the alcohol becoming converted into acetic acid. The rule
now was to add nothing whatever which could by any possibility
change the chemical or therapeutical character of the preparation.
The only feasible method of securing purity in distilled water was
to have it freshly prepared as required, and the same rule applied
to many other things, particularly to mercurous oxide. There
ought to be a well-understood limit to the meaning of the word
“ preservative.” Some people seemed to think that it meant that
a particular liquid or solid might be kept unchanged through the
ages, but that was not required. Practically a reasonable length of
time, differing with different preparations, should always be under¬
stood. As sugar had been mentioned in connection with French
pharmacy and his own name, he might say that he was
sufficiently French to recognise the extreme value of sugar as a
preservative. He might mention two cases as illustrations, one,
confection of Cassia fistula, of which he had to make large quantities
at one time, and which would not keep beyond a fortnight, at the
outside, and in some states of the atmosphere not so long, and the
other a preparation of Iceland moss, both of which kept well for a
considerable time when a certain quantity of sugar was added.
He congratulated Mr. Martindale on his paper, and particularly
on the practical illustrations he had given in connection with it.
Mr. Sage said acetic acid was an excellent solvent in many
cases, but certainly acetum scillae, acetum colchici, and acetum
ipecac, did not keep well. Some time ago he had to
examine a number of acetse which had all gone wrong, having
thickened and formed a jelly-like mass, though they were obtained
from several sources, and he found this change was due to the
Bacillus xylimus, which formed a large amount of cellulose round
each individual cell. He found this was obviated by warming to a
temperature of about 150° F. With regard to distilled water, he
did not think it was so bad as it was made out, and the fault lay
rather with the retailer than the manufacturer. He should like to
know whether in speaking of ointment of cocaine Mr. Martindale
referred to the muriate or the pure alkaloid. He believed the
ideal preservative of the future was formaldehyde, the use of
which for manufacturing purposes gave the best results.
In the milk trade it was largely used, the addition of half
a pint of a 20 per cent, solution to a churn of milk being
quite sufficient to keep it for eight or ten days, according
to the weather, and in that proportion it was practically an inert
body. It was only in a strong solution that it formed an insoluble
preparation, which was put on the market as a dressing under the
name of glucol.
Mr. Martindale said he meant the pure alkaloid when he
referred to cocaine ointment. The aceti were probably prepared
better if heated, but in the case of acetum scillse it might heighten
the colour. He still had a very poor opinion of distilled water, the
only remedy being to have it freshly distilled.
The President then moved a vote of thanks to Mr. Martindale,
which was carried unanimously.
Holzine. — According to Aufrecht, holzine, a newly introduced
antiseptic liquid, is composed of menthol andformic aldehyde, 17 '5 ;
methylic alcohol, 81 5. The proprietor, however, states that the
liquid contains from 60 to 70 per cent, of formic aldehyde. — Pharm.
Zeit., xli., 672.
THE SALE OF CALCIUM CARBIDE.
HOME OFFICE MEMORANDUM.
With a view to assisting Local Authorities in dealing with
applications for licenses to keep Carbide of Calcium, the following
observations as to the character and prevention of the risks
attaching to such keeping have been drawn up : —
1. Carbide of Calcium is a solid substance which, while not
itself inflammable, evolves, when brought into contact with
moisture, a gas (acetylene) which is of a highly inflammable
character.
2. This gas when mixed with air or when under even slight
compression becomes powerfully explosive.
3. Carbide of Calcium, unless carefully manufactured from suit¬
able materials, is liable to contain impurities which, when the
carbide is acted on by water, evolve phosphoretted or siliciuretted
hydrogen, gases which, when evolved in appreciable quantities,
would render the acetylene produced liable to spontaneous
ignition.
4. In addition to the risks indicated above, acetylene gas is
capable of forming an explosive compound when brought into
contact with copper.
5. The character of the apparatus to be used in connection with
the production of acetylene gas from Carbide of Calcium is inti¬
mately connected with the question of safety ; for example, grave
risk may arise from the heat developed by a too rapid conversion
of the carbide into acetylene gas ; or from the apparatus per¬
mitting escape or leakage of gas which is being formed, or not
allowing a free passage of the gas from the generator into the
holder and so causing excess of pressure in the generator or other
part of the apparatus.
6. Risk might also arise if proper provision were not made for
dealing with the residue of the Carbide of Calcium which has been
used for making acetylene gas (viz., lime), as such residue might
contain Carbide of Calcium which has escaped decomposition.
It will therefore be obvious that Local Authorities, in granting
licenses for Carbide of Calcium, should have regard to the fore¬
going risks, and with that view should make provision : —
(a.) For the exclusive use of hermetically closed packages for
the keeping and conveying of Carbide of Calcium.*
(b. ) The adequate ventilation of the place where the Carbide of
Calcium is present.
(c. ) The prohibition of any powerful compression of the gas
produced in the apparatus or receptacles employed.
(d. ) The keeping and use of pure Carbide of Calcium only, and
the establishment of efficient arrangements for the sampling and
testing of the Carbide.
(e.) The exclusion of copper from all vessels or apparatus used
with or for Carbide of Calcium and the gas produced therefrom.
(/.) The use only of an apparatus which the Local Authority
have satisfied themselves, under competent advice, is of a safe and
suitable character, and the prohibition of the employment for the
manipulation of such apparatus of any person other than a
properly instructed and capable operator.
(gr.) The safe disposal of the residue and the prohibition of its
introduction into sewers, cesspools, etc., unless mixed with at
least ten times its bulk of water.
It will, in all cases, be for the Local Authority very carefully to
determine whether the premises proposed to be licensed are
themselves suitable for the purpose, regard being had to the
formidable consequences (from fire or explosion) which might
result from the careless or imperfect observance of any of the
imposed conditions, especially in dwellings or in places or premises
where large numbers of persons are liable to assemble.
VIVIAN DERING MAJENDIE, Colonel,
H.M. Inspector of Explosives.
* The 9th Section of the Petroleum Act specifies among the conditions, which
may be included in a license under that Act, the mode of carrying within the
district of the Licensing Authority.
Mabch 13, 1897]
PHARMACEUTICAL JOURNAL.
235
Pharmaceutical Journal.
A Weekly Record of Pharmacy and Allied Sciences.
ESTABLISHED 1841.
Circulating in the United Kingdom, France, Oermany,
Austria, Italy, Russia, Switzerland, Canada, the
United States, South America, India,
Australasia, South Africa, etc.
Editorial Office: 17, BLOOMSBURY SQUARE, W.G.
Publishing ai\d Advertising Office : 5, SERLE STREET, W.C.
LONDON: SATURDAY, MARCH 13, 1897.
PROPOSED AMENDMENT OF THE FOOD
AND DRUGS ACT.
The Bill introduced by Mr, Kearley to consolidate and
amend the law relating to the Sale of Food and Drugs bears
upon the face of it evident indications of having been
inspired by the Society of Public Analysts. The draft of a
Bill prepared by the Council of that Society some two years
ago has probably been the basis upon which Mr. Kearley’s
Bill has been constructed. In regard to its most important
feature, the establishment of a Board of Reference — competent
to consider and decide the various questions arising in the
administration of the law for preventing fraudulent and
injurious adulteration — there cannot be any doubt as to the
great need for such an authority, or that a properly con¬
stituted Board would be very useful from every point of view.
But while Mr. Kearley’s Bill is entitled to approval, so
far as the recommendation of such a Board of Reference is
concerned, it does not appear to be the better for the mani¬
pulation by which it has been evolved from the draft of the
Society of Public Analysts. Some of the definitions in the
second clause are far from being satisfactory, for instance,
that of the term “ drug” as meaning any substance vegetable ,
■animal, or mineral used in the composition or preparation of
medicines. Here the words we have italicised are certainly
open to objection as leaving out of account a number of
substances used as drugs which do not come under any one
of the three classes. Again, the definition of the word
Xi butter ” seems superfluous.
The penalties to be imposed and the proposed advertise¬
ment of convictions, either in newspapers or on the premises
of persons convicted, in such manner as the Court may order,
do not appear to be inappropriate in cases where there is good
Teason for the conclusion that fraudulent or injurious
adulteration has been practised deliberately, but there is no
lack of evidence that a conclusion to that effect may some¬
times be arrived at without sufficient reason. In such
instances unmerited hardship might be inflicted under the
influence of such prejudices as are not unfrequently
manifested in regard to the subject of adulteration. To
take the case of such an article as coffee, there can be no
doubt that a large proportion of the community have
no idea of attaching to this word the meaning that a
public analyst or any person of refined taste would have. In
deciding that the sale of a brown powder consisting chiefly of
chicory is an offence to be punished, and not merely a necessary
compliance with an imperative popular demand, the circum¬
stances of the sde must be taken into account. Without
any desire to defend or palliate that practice of adulteration
which is said to be a form of competition, it may be con¬
tended that the ex cathedra opinions sometimes put forward
as to what articles of food and drink should be, cannot be
accepted as the basis on which an Adulteration Act is to be
administered. The offences described in the fifth clause of the
Bill do not very materially differ from those in the existing
Act, but there is a very proper provision that absence of
prejudice to the Inspector purchasing an adulterated article
shall not be a good defence to a prosecution. This provision
admits the paternal nature of the legislation it is true, but there
is no reason for attempting to conceal a fact that is so evident,
especially when the attempt would entail risk of failure in
bringing an offender within the scope of the law. The
qualifications introduced by the use of the words “ injurious
to health” and other corresponding phrases are left in Mr.
Kearley’s Bill as they stand in the existing Act and, in all
instances where they apply, the services of the Board of
Reference would be required to decide on the questions raised
in regard to any ingredient added to or abstracted from an
article of food, drink, or drug.
The proposed constitution of the Board of Reference is
somewhat remarkable. The need of medical and chemical
knowledge is admitb d by the proposal that two of its
members shall be nominated by the General Medical Council
and the Institution of Chemistry respectively, and that the
principal officer of the Government Laboratory at Somerset
House shall be a member of the Board. Technical interests
are also considered by the proposal that the Local Govern¬
ment Board, the Board of Agriculture, the Pharmaceutical
Society, the London Chamber of Commerce, and the Associa¬
tion of Chambers of Commerce of the United Kingdom shall
each nominate a member of the Board, but why the Society of
Public Analysts should nominate two members of the
Board is not so easily comprehensible. As the Society con¬
sists chiefly of members who are public functionaries
engaged in the work requisite for the administration of the
law, they would be in almost all instances more or less con¬
cerned in the prosecutions instituted and, though not
exactly interested parties, at any rate in such a position
as to disqualify them from acting as members of the
Board of Reference. Modesty has so far prevailed in
this recommendation that it is suggested the Society of Public
Analysts shall be represented by only one-fifth of the Board,
whereas the original idea was that the Society’s nominees
should constitute one-half of the Board, and it may be
expected that when the matter comes to be considered by the
House of Commons a further elimination of the. Society’s
representatives will take place. This is probable from con¬
sideration of the fact that the kind of service which Public
Analysts would be able to render as members of the Board
would be fully provided by the Somerset House Chemist and
the nominees of the Institute of Chemistry and the Pharma¬
ceutical Society. The constitution of the Board of Reference
is the most important point to be considered in regard to
amendment of the Food and Drugs Act, because it is probable
that it would in reality constitute a tribunal for the decision
of almost all cases of prosecutions, and having power against
which there would appear to be no provision for appeal.
PHARMACEUTICAL JOURNAL.
[Mabch 13, 1897
236
ANNOTATIONS
The Western Chemists’ Association of London has been first in
the field with an announcement of a discussion on the proposed new
bye-laws of the Pharmaceutical Society. This discussion will take
place on Wednesday next, March 17, at the usual place of meeting
- — the Westbourne Restaurant, Craven Road, W. — and is to be
opened by the President of the Association, Mr. J. W. Taplin.
Members and Associates of the Society in and about London should
find this an excellent opportunity for expressing their approval
of the proposed bye-laws, and so strengthening the hands of the
Council. A discussion on the same lines will take place under the
auspices of the Cambridge Pharmaceutical Association on Friday,
March 19.
The Abolition of the Preliminary Examination is not a
matter that should require much consideration. As a test of
ordinary scholastic education for persons proposing to adopt
pharmacy as a profession, the examination is totally inadequate.
More than that, it is capable of exercising a mischievous influence,
by affording a basis for the unfounded supposition that pharmacy
is a calling requiring but a slight intellectual outfit. The effects
of such notions as this are apparent on all sides, and the sooner,
therefore, the examination is abolished, and’ pharmacy put upon a
similar footing to other professions in the matter of preliminary
education, the better for all parties concerned — the public, regis¬
tered chemists, and candidates for qualification.
The Proposed Fee for the Minor Examination may be
regarded as being equally a matter of course. It is unreasonable
that a minority of the members of the trade, because they choose
to band themselves together voluntarily for the advancement of
their calling, should be called upon to bear the expense attending
administration of the Pharmacy Act while the majority contribute
nothing, though sharing equally the incidental benefits. And this
fairly represents the position of affairs with respect to the registra¬
tion of chemists and druggists and the administration of the
Pharmacy Acts in the public interest. It may be contended then that
the examination fee should be sufficient to cover the cost of the
examinations, of maintaining the Register, and provide ample
means of meeting the cost of enforcing or supporting the Acts.
The Registered Chemist and Druggist at present secures
advantage at no cost to himself and furnishes nothing towards the
expense of administering the protective sections of the Pharmacy
Acts. The best possible means of providing for these registration
and administrative expenses would be the payment of an annual
registration fee by all chemists and druggists, but failing powers
to enforce that, resort must be had to an increase in the amount
of the qualifying examination fee, which is, to all intents and
purposes, also a life registration fee, and, even with the increased
amount, exceedingly cheap.
A Permanent Defence Fund, for the protection of pharma¬
ceutical interests generally, is an additional desideratum, and such
a fund can only be accumulated if the income of the Pharma,
ceutical Society, as an administrative body, is fairly in excess of
its expenditure. There is no reason whatever why the income of the
Society as a voluntary association of pharmacists should be
devoted to the protection of outside interests, but there is every
reason why each person who obtains the legal qualification should
contribute a reasonable amount in defence of that qualification.
Such an amount each person will, under the new bye-laws, be called
upon to pay, and that is nothing but what common justice
demands. Supporters of the Society will be required to pay the
increased fee, no less than non-supporters, and their annual
subscriptions in addition. They will still, therefore, occupy
the position of paying more in proportion towards the
advancement of pharmacy than their fellows wdio disapprove of
union in self-defence.
A Pharmaceutical Field Night is the term that seems fitly to
apply to the Evening Meeting on Tuesday. Both Mr. Umney and
Air. Martirdale dealt with points of great practical importance, and
the meeting more nearly approached the ideal of what such assem¬
blies should be than has been the case for some time past. The
desirability of a knowledge of the histology of drugs being
possessed by pharmacists should be manifest to all who study Air.
Umney’s paper. In addition, it may not be amiss to observe that the
screen projections from sections of fruits, which were exhibited
during the evening, indicated the desirability of a more practical
acquaintance with the details of photo-micrography than is
generally possessed.
The Pharmaceutical Football Club has been able to arrange
an interesting fixture for Saturday afternoon, March 20, when the
past and present students of the School of Pharmacy will be
matched together. The “ Old Boys ” team has been got together
by Air. A. F. Surfleet, and will include many regular players in
the “ Square ” teams during the past five years. The match will
take place at Wormholt Farm, Shepherd’s Bush, and it is hoped
that many old students and friends will endeavour to be present,
as the occasion promises to be one of considerable interest.
A Case of Substitution is reported by the Times of India, which
is curious as showing to what legal absurdities an apparently
insignificant transaction in a chemist’s shop may give rise. A pre¬
scription ordering “ Cream of Malt and Cod-liver Oil ” was sent to
be dispensed in Madras, without any particular preparation being
specified, and the assistant supplied an article of a different make
to that which the patient had been in the habit of taking. Thereupon,
the customer commenced criminal proceedings against the assistant,
and succeeded in inducing the Presidency Magistrate to convict
the defendant, and fine him Rs. 200. An appeal to the High Court,
however, resulted in the conviction being promptly and properly
quashed, and as the local paper remarks, the moral of the case is.
that when a man wants a particular preparation he should always
be careful to specify the maker’s name.
The Kinninmont Prize, consisting of a gold medal and books,
will be offered for competition in Alay or June, and intending com¬
petitors must send in their names to the Secretary, Mr. W. L.
Currie, 223, Byres Road, Dowanhill, Glasgow, before the end of
April. The subjects of examination are botany, magnetism and
electricity. Assistants in Glasgow, or the counties of Argyle,
Ayr, Bute, Dumbarton, Dumfries, Kircudbright, Lanark, Renfrew,
and Wigtown are eligible to compete, if they have been engaged
in the district for the six months previous to the date of exami¬
nation, or others who have served their apprenticeship in any of
the places named but have removed within twelve months of the
date of examination.
MARCH 13, 1897]
PHARMACEUTICAL JOURNAI
23 7
The Liverpool Chemists’ Association holds its annual dinner
on Thursday next, March 18, at the Adelphi Hotel, well known
to those who attended the last Conference. Tickets (5s. each) may
be obtained of Mr. H. 0. Dutton, Rockferry. From Liverpool,
also, we have received an intimation that the Major Examination
Courses are about to commence in the School of Pharmacy,
University College. Courses have been arranged in chemistry,
physics, botany, and materia medica.
Local Organisation in Pharmacy continues to proceed apace,
and it is satisfactory to note that towns which are too small to
carry on independent associations satisfactorily are uniting their
efforts to form district associations. The latest indications of this
tendency are forthcoming from districts so far apart as Dundee
and North Staffordshire. The Committee of the Dundee Chemists’
and Druggists’ Association is appealing to all members of the craft
in some fifteen towns in the district, to form a new association
covering the whole of the county of Forfar and district. A merely
nominal subscription has been decided upon, and the first general
meeting and annual dinner will be held at an early date. The
North Staffordshire and District Chemists’ Association began
operations on Thursday last, when officers were elected, and a
dinner was held to smooth the wheels. Finally, we learn that an
association has been formed at Oxford, as a result of the activity
of the P.A.T.A. in the district.
The Late Sir Benjamin Richardson was so fortunate as to
be bound apprentice to a surgeon in a country district in Leicester¬
shire, on leaving school. That, of course, was the regular custom
in the medical profession in those days, and had a good deal to
recommend it. In Sir Benjamin’s latest work — ‘ Vita Medica ’
— which has just been published, and may be regarded as a
retrospect of his career, he repeats what he often said during
his lifetime — that this method of introduction to the pro¬
fession, now practically abandoned, was the best that could
be, and ought to have remained untouched. It was, he
observed, a fruitful source of income to all respectable prac¬
titioners, and kept them well up to the mark ; it also made good
openings for introductions and practice, was warmly appreciated
by the public at large, cultivated well a common field, and effected
a sound and general good. “ The chief benefit was to the student
himself, for he learned early in life all the practical branches he
afterwards most needed ; he soon acquired as ‘ the young doctor ’
the style and manners of the medical man ; he learned the mode of
entering the sick-room, and of conversing with the sick ; he
practised naturally the true etiquette of physic. ” And no one can
gainsay that these are advantages the lack of which is not easily
compensated for.
Army Medical Compounders are not required to know much of
what a dispenser ought to know, as was shown in these pages a
few weeks ago (ante, p. 131), and it would appear that the
authorities are slowly beginning to realise the fact, as they propose
to add elementary chemistry to the list of subjects in which
examination will be compulsory after May 31 next. But the
knowledge of chemistry required will be of little use to the
individual as a compounder and dispenser, for the questions to
be asked must be within the limits of Harrison and Bailey’s
‘ Chemistry for All,’ a very good book for juveniles but
absolutely useless as a text-book for dispensers. It was
written, we believe, to meet the requirements of the curious
‘‘alternative” first stage in inorganic chemistry (theoretical) of
the Science and Art Department, which specifies an extremely
limited acquaintance with solution, air, water, carbon, sulphur,
chlorine, acids, alkalies, ammonia, lime and clay, lead, iron,
copper, mercury, sodium, acetic acid, tartaric acid, fat and oils,
sugar, starch, gluten, and spirit. Presumably four “comprehen¬
sive” questions (vide p. 131) will be asked about all these things,
that being the number in each subject which commends itself to the
intelligence of the Army Medical Staff, or those under whom they
act. But why should pharmacists learn so much science, if so
little will suffice for accurate compounding and dispensing ?
East India Opium is the . subject of a recent return to the
House of Commons. This shows that during tlje year 1894-95,
537,556 acres of land was under poppy cultivation in British India,
39,765 chests of opium was manufactured in the Government
factories, and 68,834 chests were exported to China and other
countries from India. In Central India and Rajputana, 322,945
acres of land was under poppy cultivation, but no correct
information is forthcoming respecting other Native States.
Excise opium is manufactured for local consumption in India.
It is packed in chests containing 1 maund and 20 seers each, and
the consistence of the opium when manufactured is about 90°.
Provision opium is manufactured at a consistence of 75° at the
Patna (Behar) Factory, and 71° at theGhazipur (Benares) Factory,
and is intended for export. It is packed in chests, each of which
contains 1 maund, 28 seers and 2 chittaks, or 140^ lbs. The
Medical opium made at the Patna (Behar) Factory and supplied to
the Medical Department, and to Charitable Medical Institutions in
India, is not included in the figures given in this return. The
average quantity of this opium annually manufactured during the
four years ending with 1894-95 was— cake opium 410 lbs.,
powdered opium 677 lbs.
Lieutenant Dan Godfrey, who has during so many years contri¬
buted towards the enjoyment of visitors to pharmaceutical gather¬
ings, has been the recipient of a handsome and gratifying testimonial
from the past and present officers of the Brigade of Guards, on the
occasion of his retirement after forty years’ service as bandmaster
of the Grenadier Guards. The presentation, which consisted of a
large silver salver with tea and coffee service and kettle, was made
at the Guards’ Club, by General Prince Edward of Saxe- Weimar.
The Bristol Pharmaceutical Association Dinner, a detailed
report of which is unavoidably deferred until next week, along
with other interesting matter, was held on Wednesday night and
is described as having been a great success. Mr. B. Allen, Presi¬
dent of the Association, occupied the chair, and Mr. Charles
Townsend, J.P., the vice-chair. The toast of “The Pharma¬
ceutical Society of Great Britain” was proposed by Mr. E. Young
and ably responded to by the Local Secretary for Bristol, Mr. B.
Keen, who spoke at some length and much to the purpose.
Popular Weeklies publish a great deal of rubbish,' in the form
of special articles of such unutterable foolishness that we consider
it both unnecessary and undesirable to refer to them as a rule. A
copy of Cassell's Saturday Journal, sent by a correspondent, con¬
tains an article entitled “ Dodges in the Drug Trade,” which is in
no degree more remarkable for its inaccuracies than other similar
effusions, except that the writer — if he knows anything of the
subject — has betrayed his connection with the family of Ananias
more palpably than is usual in such instances. This much being
said, it seems unnecessary to comment further on the matter.
238
PHARMACEUTICAL JOURNAL.
[Mabch 13, 1897
PHARMACEUTICAL SOCIETY.
DONATIONS TO THE LIBRARY AND MUSEUM.
At a meeting of the Library, Museum, School and House Com¬
mittee, held on Wednesday, the 10th inst., the Librarian presented
the following report of donations : —
To the Library (London).
Philosophical Society of Glasgow : — Proceedings, vol. 27.
T. B. Browne, Limited, London : — ‘ The Advertiser's ABC,’ 1897.
Mr. Joseph Ince, London French’s ‘ Art of Distillation,’ 1653.
American Pharmaceutical Association : — Proceedings, 1896.
Chemists’ Assistants’ Association, London : — Proceedings, 1895-96.
University of Durham : — Calendar, 1897.
Mr. J. Barker Smith, London : — 1 Quantitative Estimation of Urine,’ 1897.
Botanical Society, Edinburgh ; — Transactions and Proceedings, 1894-96, vol.
20, parts 2-3.
Radcliffe Library, Oxford : — Catalogue of Books added during 1896,
The following donations were reported by the Curator : — •
To the Museum (London).
The Director, Royal Gardens, Kew : — Leaves of Rhytidophyllum tomentosum, from
Jamaica; leaves of Rhus juglandifolia, from Guayaquil.
Professor L. Planchon, Montpellier : — Authentic specimens of the root of Alkanna
tinctoria ; roots of Chrysobalanus Icaco and Strychnos, M'Boundou ; stem of Acalypha
Neo-Caledonica ; barks of Richeria grandis, Tecoma pentaphylla and Quercus
coccifera ; twigs and leaves of Combretum Raimbaulti ; leaves of Orchis militaris,
adulterated saffron ; fruits of Angrcecum fragrans, Panda oleosa, Poga oleosa,
Quassia africana, and Terminalia mauritanica.
Mr. H. Haensel, Pima-on-the-Elbe : — Specimens of Thuringian Fennel Fruits
and of the Oil distilled from them, Oil of African Sandalwood, and Frejar Oil ;
Fruits of Amomum Daniellii.
Messrs. Wright, Layman, and Umney, London : — Specimen of adulterated
Saffron ; Leaves of Zataria multiflora ; and the specimens of the Fennel Fruits
and Oils of Fennel, exhibited at the Evening Meeting.
Mr. J. O. Brathwaite, London : — The Microscopic Sections of Fennel Fruits
exhibited at the Evening Meeting.
Mr. H. Collier, Guy’s Hospital : — Specimens of Esoga Nuts.
Mr. J. Moss, F.I.C., London : — Specimens of five West African remedies.
IWEETIflGS Op SCIENTIFIC SOCIETIES
- ♦ -
Chemical Society, Thursday, March 4. — Mr. A. G. Vernon
Harcourt, F.R.S., President in the chair. — In many respects this
meeting was an exceptionally interesting one, so much so indeed
that the new unwritten law regarding the time taken by
authors to say all they had to say in half an hour was entirely
forgotten or ignored, and Dr. Sydney Young, the first con¬
tributor, was allowed to occupy an hour and a quarter,
Mr. Heycock being another transgressor in this respect.
Before proceeding to the papers a question was asked by Mr.
C. E. Cassal as to why the name of a certain candidate was
withdrawn from the Ballot-List. At the mention of the candidate’s
name, everyone of course looked up his certificate, and it was at
once apparent that there was something out of order, for it read
more like a business card than anything else. Mr. Cassal was
informed that the matter had been settled by private letter.
Professor Armstrong put in a few words and then the matter
dropped. The first paper was on
Some Hydrocarbons from American Petroleum,
its first instalment being “Normal and Iso-Pentane,” by Sydney
Young, D.Sc., F.R.S., and G. L. Thomas, B.Sc. Another paper
by Dr. Sydney Young, read by him immediately after the first, was
entitled “ The Vapour Pressures, Specific Volumes, and Critical
Constants of Normal Pentane, with a Note on the Critical Point.”
Dr. Young had no difficulty in satisfying at least the chemical
portion of his audience of the identity of iso-pentane obtained from
petroleum or chemically prepared. The physicists, however, were
not so easily convinced, and Professor Armstrong went the length
of saying that the matter had not been proved. American
petroleum is a very complicated mixture of hydrocarbons, olefines,
pentanes, and naphthenes, and Dr. Young mentioned as a curious
fact that the aromatic hydrocarbons distil before their true boiling
oints. The author had some trouble in separating the naphthenes,
ut had no difficulty with the aromatic hydrocarbons, pentanes,
and olefines. A diagram of the distilling apparatus was drawn on
the board, and Dr. Young described the progress of the oil through
a dephlegmator into a still-head, the temperature of which was
regulated in an ingenious way by means of a revolving spiral or
screw, then through a condenser into the receiver.
The second paper was chiefly composed of figures, and those, like
railway time tables, only become interesting when it is necessary
to consult them. In the discussion which followed upon these
papers, the President had a good deal to say, as he had had some
experience in American petroleum. He had always taken the
precaution of purifying the crude material first of all with sul¬
phuric acid and caustic soda, and he thoroughly agrees with
Dr. Young as to the identity of iso-pentane obtained from the
natural source or prepared chemically. He could detect no differ¬
ence in “illuminating” experiments. Professor Thorpe at this
stage entered the room, and seemed somewhat surprised when
the President suddenly asked him if he could say anything on 'the
subject. As the Professor has done work in this direction, how¬
ever, he soon saw how matters stood, and then threw in his vote
with the chemists. He had started with amylic alcohol, and isolated
the iso-pentane by different methods. — Dr. Young, in answer to Pro¬
fessor Thorpe’s question as to how he had prepared his iso-pentane,
said he had done so by means of the copper-zinc couple and amyl1
iodide. — The viscosity, Professor Thorpe went on to say, was abso¬
lutely identical in all his experiments, even when the pentanes had
been prepared by different individuals, and By different methods ;
therefore, he said, they were not dealing with two different sub¬
stances. — Dr. Armstrong could not understand the aromatic
bodies clinging to each other in a way not in accordance with their
boiling points. — Dr. Young replied, and the next paper was taken.
On the Freezing-Point Curves of Alloys Containing Zinc,
by C. T. Heycock, F.R.S., and F. H. Neville. It is unfortunate
that some idea of the personality of an author cannot be instilled
into a report ; suffice it to say, however, that Mr. Heycock held
his audience spell-bound for the best part of an hour, and he
contrived to serve up a dish of the dry bones of science in the
most savoury manner imaginable. His paper commenced with a
description of the effect of zinc when added to certain metals,
depressing the freezing point in some cases. The freezing point
curve of an alloy of zinc and cadmium, and of tin and zinc are at.
first almost the same, but the latter afterwards lies above that of
the former, and so on with other metals, such as aluminium and
bismuth. Mr. Heycock can discover no evidence of chemical
products, but considers that they are simply solutions. Some metals
raise the freezing point. Silver, gold and copper do so. In these latter
alloys, however, Mr. Heycock says chemical compounds are formed,
and that it is not altogether improbable that we should have the for¬
mulae AgZn, AgZn2, AgZn;}. The silver-zinc alloy at a high tempera¬
ture — 300° C. or higher — and then suddenly cooled, has the curious
property of turning a red or pink colour, and this coloration is only
superficial. The alloy is naturally a grey colour, just like silver or
zinc. The phenomenon, Mr. Heycock has proved, is not brought
about by oxidation, and he is quite in a dilemma as to what the
cause of it is. The alloy is brittle and cannot be rolled. The next-
paper was by A. H. McConnell and E. S. Hanes on—
The Oxides of Cobalt, Cobalt Dioxide, Cobaltous Acid,
AND COBALTITES.
The authors state that they have made some investigations
upon the action of various oxidising agents on the three known
oxides of cobalt, viz. : CoO, Coa04, and Co203, with the object of
determining the part played by oxidation in the technical manu¬
facture of the pigment cobalt blue. Their paper is a critical
review of the present state of our knowledge of the subject, and
the evidence they bring forward shows that when cobaltous
hydrate is acted upon by chlorine, bromine, hydrogen peroxide,
and other oxidising agents, a new oxide of cobalt is formed
which is partially soluble in water, forming cobaltous acid,
analogous to manganous acid present in the manganites.
This cobalt dioxide and cobaltous acid have hitherto been re¬
garded as hypothetical compounds. The authors also show that
when the oxidation is conducted in the presence of an alkali
carbonate or acid carbonate, a deep green solution of extraordinary
colouring power is obtained. One part of cobalt can be easily
detected by this method in 100,000 parts of water. Mr. McConnell
who read the paper, handed a bottle containing the delicate green
solution to the President, and the colour was distinctly visible
from the benches. The green colour is due to potassium or sodium
cobaltite, according to the alkali employed. These new
compounds, or rather newly discovered compounds, are very
unstable, and up to the present the authors have not been able
to isolate them. But from analyses of this green solution
they show that cobaltous acid forms alkali cobaltites on the type
of potassium cobaltite, to which they assign the formula K.2OCo02.
March 13, 1897]
PHARMACEUTICAL JOURNAL.
239
A number of interesting reactions of these new compounds are
described, which prove that the views put forward in explanation
of this green colour by Mr. R. G. Durrant, M.A., in two recent
papers read before the Society are altogether untenable. The
last paper was on
A New Synthesis in tiie Sugar Group,
by H. J. H. Fenton, M.A. The author gave the gist of his paper
very briefly, as it was already long past the usual hour for closing.
It appears that this new body is dihydroxymaleic acid. — Among
the papers taken as read was one entitled “ A Synthesis of Citric
Acid,” by W. J. Lawrence, B.A., Ph.D.
THE WORLD Op PHARMACY.
- 4 - -
BUSINESS MEETINGS.
British Pharmaceutical Conference, Wednesday,
March 3. — Dr. Symes, President, in the chair. — At a meeting of
the Executive Committee, on the motion of the President,
seconded by Mr. Atkins, the Secretary was requeestd to send to
the widow of the late Mr. Schacht a letter of condolence and an
expression of the deep respect and admiration in which her hus¬
band had been universally held by the officers and other members
of the Executive of the British Pharmaceutical Conference. — A
letter was read from Mr. D. Hooper, resigning his position
as Colonial Secretary for the Presidency of Madras, in consequence
of his departure from Ootacamund for Calcutta. Mr. Hooper
was cordially thanked for his services, and upon his nomina¬
tion, Mr. W. E. Smith, of Madras, was elected as his successor.
— The following gentlemen were appointed as a Sub-Committee to
revise the Blue List previous to its distribution amongst
members : — Professor Greenish, Messrs. Bird, Moss, Naylor, and
J. C. Umney. — An application was received from the Liverpool
Pharmaceutical Students’ Association to be supplied annually
with a copy of the Year-Book. It was decided to grant the
request. — A circular was read from an International Pharma¬
ceutical Congress to be held at Brussels in August, inviting the
co-operation of members of the British Pharmaceutical Conference,
The President was requested to acknowledge its receipt, and to
express the sympathy of the Executive with the objects of the
proposed Congress. — Nine gentlemen, having been duly nominated,
were elected bo membership.
Liverpool Pharmaceutical Students’ Society, Thurs¬
day, March 4. — Mr. John Jones, President, in the chair. — Mr.
R. C. Cowley read a paper on
The Analysis of Fatty Oils.
The report of this lecture is unavoidedly deferred. In the dis¬
cussion which followed, Mr. T. H. Wardleworth confessed that
he was somewhat disappointed that Mr. Cowley had not mentioned
any tests by which the genuineness or otherwise of cod-liver
oil could be proved. During the recent high prices which cod-liver
oil brought, it was more than ever necessary to guard against
adulteration with other fish oils, and he had found that for this
purpose the B. P. test was absolutely useless; could Mr. Cowley
indicate a better one ? — Mr. Peirson asked if there was any ready
and good means of distinguishing between almond oil and oil
of peach kernels, whilst Mr. Marsden wished for a good test for
nut oil, and mentioned that of Mr. Holmes, depending on
the nutty flavour given off when the oil adulterated
with nut oil is poured on hot mashed potatoes.
Mr. Cowley had not mentioned the detection of hydrocarbon oils,
nor had he said that he had used the viscosimeter advised by
Boverton Redwood. — In reply, Mr. Cowley said that there was no
single test that he could mention as being of use in cod-liver oil
examination, and he agreed that the sulphuric acid test was not of
the slightest utility for distinguishing admixture of other fish oils.
For olive oil the nitric acid test was the best all round, whilst for
proving that the adulterant was nutroil, the presence in that oil of
arachidic acid gave a ready means of accomplishing the detection
by throwing it out as a lead salt which, unlike oleate of
lead, is insoluble in ether. The iodine absorption test he
had found very good for fixed oils, though he agreed with
what had just been said as to its uncertainty where essential
oils are concerned. He could not say that he had any great
experience in the use of the viscosimeter, nor could he give Mr.
Peirson the test he required for distinguishing peach kernel oil
from almond oil. Hydrocarbon oils, including rosin oil, were
easily found out by the manner in which an oil responded to the
saponification test. — Mr. H. Wyatt, jun., said that he had come
across a test for peach kernel oil in an Italian journal, depending
on the production of a precipitate of the small quantity of benzalde-
hyde naturally contained in the oil when a strong solution of an
alkaline bisulphite is added, but he could not say anything with
regard to its utility.
SOCIAL MEETINGS-
Chemists’ Assistants’ Association, Thursday, March 4.
— The nineteenth annual dinner of the Association was held at the
King’s Hall, Holborn Restaurant. The gathering was a record
one, the company numbering about two hundred and seventy.
Mr. C. Morley, President of the Association, occupied the chair,
and was supported by Mr. Walter Hills, President of the Pharma¬
ceutical Society, Sir William H. Broadbent, M.D., Professor H. G.
Greenish, Dr. Macnaughton-Jones, Dr. J. Attfield, and Dr. Symes.
There were also present : Messrs. R. Bremridge, J. C. Umney,
C. B. Allen, F. Clarke, G. Hodgkinson, J. J. Ward, A. Cooper,
J. W. Taplin, A. J. Philips, Mackey, J. Moss, H. C. Wright,
J. O. Braithwaite, F. C. J. Birdand many others. Messrs. E. W. Hill,
R. G. Guyer, Strother, Melhuish, Moore, Solomon, andE. W. Martin
presided over the spur tables. — At the conclusion of the repast
the Chairman proposed the toast of “ The Queen,” which was
enthusiastically responded to, and accompanied by the singing of
the National Anthem. — Mr. C. E. Robinson followed with the
toast of
“The Medical Profession.”
In a short and effective speech he alluded to the friendly relations
existing between the medical profession and pharmacy, and
coupled with the toast the names of Sir William Broadbent and
Dr. Macnaughton-Jones. — Sir William H. Broadbent, who was
received with much applause, expressed his thanks for the way in
which the toast had been honoured, and said he was much impressed
by the excellent and impersonal manner in which it had been proposed
by Mr. Robinson. He represented the sympathy which existed
between them and the medical profession, and the expression of
that sympathy was his presence with them that evening. As a
rule public dinners were on his list of things to be avoided, but on
that occasion he felt it a privilege to be the guest of an association
which had accomplished such great results. The interests of the
medical profession and pharmacy were bound up together, their
pursuits were similar, and they were all concerned in the mitigation
of human suffering. Their education had that for its object ;
that was the tie which linked them together and constituted them
an important branch of the medical profession. He should
remember that dinner with great satisfaction, and thanked them
on behalf of the great profession which he had the honour to
represent. — Dr. Macnaughton-Jones also responded, concluding
by alluding to the services rendered by pharmacy to medicine in
connection with the action of drugs.- — At this point variety was
introduced into the proceedings by the taking of a flash-light
photograph of the entire company, and Mr. A. Ralph Melhuish
next proposed
“ The Pharmaceutical Society’.”
He said he was very pleased to see all branches of pharmacy so well
represented, both scientific, examining, and literary. The toast
of ‘ ‘ The Pharmaceutical Society ” was like that of the Queen, they
always expected it, they always got it, and they always honoured
it. Sometimes, it was true, the Society was criticised at their
meetings, but they always recognised that it was doing good work,
and that only through the Society could any lasting benefit accrue
to the trade of pharmacy. He deplored the want of support by
the majority of the trade, and hoped that chemists and druggists
would in the near future be allowed equal right with members. — -
Mr. Walter Hills, in responding, said the C.A.A. had been
always loyal and a source of strength to the Pharmaceutical
Society, and knowing the members were loyal at heart,
the Council of the Society could bear their criticisms. The time
of the annual election was near at hand, and in this connection he
might remark that fifty years ago there were seventeen London
members of Council out of twenty-one, and there were now five.
It was essential for the interests of the Society to have a fair
proportion of London members of Council, and it did not need
even the arithmetic of the Preliminary examination to calculate
what that proportion would probably be as years rolled on. He
240
PHARMACEUTICAL JOURNAL.
[March 13, 1897
would ask them to bear that fact in mind on the day of election.
He had a secret to divulge to them (which next morning would be no
longer a secret) in reference to the Preliminary examination. After
June, 1900, that examination would no longer be conducted by the
Pharmaceutical Society, but students previous to registration would
be required to produce the certificate of some approved examining
body. Practically, the examination was that demanded as a pre¬
liminary by the General Medical Council, and would stand good
for entry on either medical, veterinary, or dental studies. Besides
the ordinary subjects, those of Euclid, algebra, and a modern
foreign language were included. He looked particularly to them
as younger men for support and assistance to carry this scheme to
maturity, for it was in a sense their own, a meeting of the C.A.A.
in 1891 having passed a resolution in favour of the change now
proposed. Strong men and not weak ones were required
for the advance of their calling, and by widening the
scope of the examination a different class of men would
be brought into their ranks. Every strong man raised,
and every weak one lowered both their social and financial
standard. He trusted they would attend at the annual meeting
and show the present Council that the general feeling was with it.
He thanked them for their kind reception of the toast, and looked
to the Chemists’ Assistants’ Association to provide active and
energetic members of the Society, and in the future good
examiners and capable occupiers of the presidential chair.
Dr. J. Attfield (in the unavoidable absence of Mr. J. Harrison,
J.P., of Sunderland, Vice-President of the Pharmaceutical
Society) gave the toast of the evening,
“The Chemists’ Assistants’ Association,”
and in alluding to his long connection with the members in many
ways remarked that the objects of their Association were practically
the same as what they were many yeais ago. He found that
they endeavour to interest assistants in their calling by giving
prizes for the best essays and practical work, encouraging
pharmaceutical research, and promoting good-fellowship
amongst their members. He complimented them on the success
which had attended their efforts, as evidenced by the reports of
the proceedings, both scientific and social, which appeared from
time to time in the pharmaceutical press. A terrible amount of
envy and jealousy existed amongst pharmacists, and although all
were offered welcome to the Pharmaceutical Society, one only out
of every three or four responded to that noble invitation. It
was a sad and melancholy reflection. In 1849 the number
of pharmaceutical associations could be counted on the fingers
of one’s hand, but now the example of the Pharmaceutical
Society, and that of the British Pharmaceutical Conference
(which might be called the peripatetic Pharmaceutical Society)
had been generally followed throughout the country, an in¬
dication that pharmacists were gradually learning to pull
together. In a short time they would be in possession of a new
pharmacopoeia, which might contain questionable pharmacy, and
perhaps questionable chemistry ; they might even find on every
page something to be altered. But let them make it their aim and
duty to work in the direction of producing a better pharmacopoeia
during the next decade than the one which would appear at the
end of the year. If the Pharmacopoeia was to be worthy of an
enlightened country like theirs, research must be made by phar¬
macists all over the kingdom, and the results dealt with by a com¬
mittee of the Pharmaceutical Society in London, so that it might
be raised to the proud position of the best pharmacopoeia in the
world. Long might they prosper and do good work, and long
might they have on their Council such names as those of Mr.
Melhuish, Mr. Guyer, and their President, Mr. Charles Morley.
— Mr. Charles Morley, who on rising to respond was received
with musical honours, said he considered individual isolation was
a source of weakness in any community, and, speaking phreno-
logically, the 'thought that if there was such a bump, that of
“splendid isolation” was exceptionally well developed in the
average pharmacist. Their Association tried to remove this, and
also that want of esprit de corps alluded to by Dr. Attfield. They
were not sufficiently supported by chemists’ assistants, but he
hoped the future would see a large accession to their ranks. They
cultivated the social side as well as the scientific in the form of
Cinderella dances, conversazione, smoking concert, and social
evenings, but he did not think they could spare any more of the
scientific nights for those purposes. Light refreshments were
provided at their ordinary meetings, and . certainly most
excellent value was returned for the annual subscription of five
shillings. Mr. Morley concluded amidst enthusiastic applause.
Mr. W. Moore in a short speech proposed the toast of
“The Visitors”
to a rapidly thinning audience, and in response Dr. Symes, referring
to the comparatively non-representative character of the member¬
ship of the Pharmaceutical Society, stated that the Society did not
represent the bulk of their calling. He advised all young men to
join the Pharmaceutical Society, and the British Pharmaceutical
Conference, which latter body did much to promote sociability
and good feeling. He considered that jealousy among pharmacists
was now not more than one-tenth of what it was many years ago,
and this was due, in great part, to the Conference meeting in
different parts of the country. The members of the local com¬
mittee, brought together for arranging the details of the visit, often
found that although rivals perhaps, and competitors in business, ah
heart and socially, they were all ‘ ‘ very good fellows,” and so friendli¬
ness and good-fellowship were promoted in that particular district.
An excellent musical programme greatly contributed to the
enjoyment of the evening, Messrs. Jamieson, Thorne, Brandon
and Thomas were the vocalists, Mr. A. C. Mackadam accompanying
at the piano. The hour being late when Dr. Symes finished
speaking, the audience had been greatly diminished, but the few
who remained joined in singing “ Auld Lang Syne” with great
energy, and this concluded perhaps the most successful of the
many successful annual dinners of the Chemists’ Assistants’ Asso¬
ciation.
Edinburgh Chemists’, Assistants’, and Apprentices’
Association, Friday, March 5.— The annual supper of the Asso¬
ciation took place in the Imperial Hotel, Market Street. — Mr.
James McBain, President, occupied the chair, and Messrs. G.
Sinclair, Vice-President, and J. D. Sinclair, Hon. Sec., acted as
croupiers. — Mr. G. Sinclair, in proposing
“The Pharmaceutical Society of Great Britain,”
referred to the proposed new bye-laws, and remarked that it was
high time that all registered chemists who joined the Society
should be admitted to a direct voice in the management of the
Society’s affairs. — The toast was acknowledged by Mr. W. L.
Currie, who expressed agreement with what had been stated by
Mr. Sinclair. He would go further, and make every man who-
passed the Minor examination eligible for a seat on the Council.
He referred to the relatively small number of registered chemists
who joined the Society, and expressed a strong opinion that no-
improvement was to be expected till some effective change was
made to consolidate the Society on a truly democratic basis. — Mr.
J. A. Forret proposed
“ The Edinburgh Chemists’, Assistants’, and Apprentices’'
Association,”
which was acknowledged by the Chairman. — Mr. W. L. Currie
proposed “ The Edinburgh Chemists’ District Trade Association/’
and Mr. J. Bowman replied. — Mr. J. Rutherford Hill pro¬
posed “The Edinburgh Pharmacy Athletic Club,” and “The
Edinburgh District Chemists’ Golf Club,” the former being
acknowledged by Mr. D. Maclaren, and the latter by Mr. G.
Lunan. — “ The Ladies” was proposed by Mr. J. Sivewright, and
acknowledged by Mr. G. Coull, and “ The Chairman and
Croupiers,” by Mr. Duncan. Songs, recitations, and instru¬
mental pieces were contributed by Messrs. W. L. Currie, W.
Duncan, Rowland, A. Murray, J. Bowman, jun., P. Barneveld,
Shiels, Butchart, and Sid. Cornish, and Mr. James Crichton
acted efficiently as accompanist. — In the course of the evening, on
the suggestion of the Chairman, a collection was taken for the
Benevolent Fund, amounting to £1 15s. 0 d.
Brighton Junior Association of Pharmacy, Wednes¬
day, March 3. — Mr. W. W. Savage in the chair. — The last musical
and social meeting of the 1896-7 session was attended by a very
large number of members and friends, and an excellent programme
was rendered.
Edinburgh District Chemists’ Golf Club, Thursday,.
March 4.— A meeting was held in the Pharmaceutical Society’s
House, 36, York Place, Edinburgh, of those favourable to the
formation of a new golf club, distinct from the Pharmacy Athletic
Club. — Mr. George Lunan, who occupied the chair, moved that
the meeting form a new club, to be called “The Edinburgh Dis¬
trict Chemists’ Golf Club.” — This was seconded by Mr. James
Stott, and unanimously agreed to. A constitution and rules were
March 13, 1697]
PHARMACEUTICAL JOURNAL.
2U
then drawn up, the subscriptions to be 10*. 6 d. for honorary, 7 s. 6 d.
for ordinary, and 2s. 6 d. for apprentice members. The following
office bearers were then elected : — Honorary President, Adam
Gibson, F.C.S, ■; Captain, George Lunan ; Vice-Captain, H. D.
Alexander ; Secretary, James Stott ; Assistant-Secretary, John
'Greig ; Treasurer, W. B. Cowie ; and as members of Committee,
Messrs. Baker, Dey, Laing, Lyon, Paterson, G. Robertson, and
Stewart.
LEGAL INTELLIGENCE.
PROCEEDINGS UNDER THE PHARMACY ACTS.
Prosecutions at Glasgow.
At the Sheriff Court House, Glasgow, on Friday, March 5, a
■number of cases of prosecution instituted by the Registrar under
the Pharmacy Acts, 1852 and 1868, Mr. Richard Bremridge, came
before Sheriff Bremner Lee. — Mr. T. B. Morison, advocate, Edin¬
burgh, instructed by Messrs. Martin and Barrie, writers, Glasgow,
-appeared for the prosecutor.
The first case was against James Tulloch, assistant in the shop
of Dr. Aitken, 378, Rutherglen Road, Glasgow, who was charged
•with selling a bottle of Powell’s Balsam of Aniseed to an agent of
the Registrar on November 28.
Mr. Richardson, solicitor, who appeared for defendant, said he
would plead guilty in the event of the Sheriff deciding against him
•on certain objections to the complaint which he had to state. He
objected that the species faeti did not come within the provisions of
the Act. His client was charged with selling Powell’s balsam, but
that was not included in the Schedule to the Act. They might as
well charge a painter with selling a wallpaper containing arsenic. In
t ie second place he objected because of insufficient specification,
in asmuch as only Sections 1 and 15 of the Act were cited. Section 2,
•which described a poison, should also have been cited. He com¬
plained also of general vagueness and ambiguity. He was not
directly charged with selling morphine, but the complaint went on
■to say he sold Powell's balsam. Lastly, this complaint bore to be
brought under the Summary Procedure Acts, 1864 and 1881, and
he complained that its terms were not in conformity with the
schedules attached to these Acts. The defendant was cited to
“appear to this complaint.” The woi’ds had no meaning, and it
should have been “ appear to answer to this complaint.”
Mr. Morison said these objections were all unfounded. The
■defendant was charged with selling morphine, and it was to give
him fair notice of the nature of the charge against him that the
prosecutor explained that when sold the morphine was contained
in a bottle of Powell’s balsam sold by him. This point had been
clearly decided in the case of Bremridge v. Armson, in 1894
J2 Q„ B. D. , page 720), where it was stated that poison in a cup of
tea or a bottle of wine did not cease to be poison. It was
•quite unnecessary to cite Section 2, defining a poison. One might
.as well cite the section defining a chemist and druggist. These
.•section 3 were incorporated in the phraseology of Sections 1 and 15,
which constituted the offence here. The phrase “ to appear to a
complaint” was in constant use, and could mean only one thing. If
his Lordship wished he could add “and answer,” but he thought
±he meaning was perfectly clear without these words.
Mr. Richardson said the authorities quoted had no bearing on
.this case, because the objections had been put in after the trial,
whereas he was now putting the objections in before the trial. In
Piper’s case, too, it was proved that the quantity of poison might
be infinitesimal, and in that case it would not be struck at by the
Act.
The Sheriff repelled all the objections.
The defendant then pleaded guilty, and the Sheriff imposed a
modified penalty of £2 and £1 Is. of expenses.
The next case was against— Miss J. Noble, assistant in the shop
•of Dr. Barrie, 155, Eglington Street, Glasgow, who was charged
•with selling laudanum and Powell's Balsam to two agents of the
Registrar on November 28.
The defendant pleaded not guilty, and her employer, Dr. Barrie,
was allowed by the Sheriff to speak for her.
Mr. J. Rutherford Hill produced the Register of Chemists and
•Druggists for 1896, which proved that defendant was not duly
.registered. He also produced the bottle of laudanum and the
bottle of Powell’s balsam mentioned in the complaint, which he
had analysed and found to be poisons within the meaning of the
Act, 1868.
Alexander Spence and Joseph Tait proved the purchase of the
poisons, and declared that defendant was alone in the shop.
Dr. Barrie said there were no witnesses for the defence. He was
sure this must have been a mistake on the part of his assistant if
she sold these poisons, for she had instructions from him not to
sell poisons except when he was in the shop, and he felt sure she
never did so. These poisons were sold at his consulting hour, and
that enabled him to say he must have been in the shop°when they
were sold. He would be either in the front shop or in the consult¬
ing room. His assistant was not in the habit of selling poisons,
except when he was in the shop.
Mr. Morison said, on the contrary, his information was that the
defendant was regularly employed in selling poisons in this shop
when Dr. Barrie was not present. Otherwise there would have
been no complaint.
The Sheriff, addressing the defendant, said I am very sorry, but
I must hold you guilty. I do not think you are so much responsible
for these offences as Dr. Barrie is. "They are really more his
than yours. But these are very grave offences which he has
allowed you to commit, and I must impose a modified penalty of
£1 for each offence, and £1 Is. of expenses.
The next case was against Archibald Taylor, assistant in the
shop of Dr. Robertson, 90, Main Street, Gorbals, Glasgow, who
was charged with selling laudanum, on November 28, to an agent
of the Registrar.
Defendant appeared and pleaded not guilty. He conducted his
own case, and denied that he sold laudanum.
Mr. J. Rutherford Hill produced the Register proving that
defendant was not registered. He also produced a 2-drachm
bottle containing the laudanum mentioned in the complaint, which
he had analysed and found to contain opium and to be laudanum.
The bottle was not labelled “ Laudanum” nor “Poison.” It had
on it the words “ 15 drops in the castor oil.” Cross-examined
by defendant, Mr. Hill said the contents of the bottle had all the
appearance of laudanum, and it certainly contained a considerable
quantity of opium.
Defendant : Did you estimate the quantity of morphine ?
Witness : No, I only proved the presence of opium in quantity.
Defendant: Well, you are not an analyst at all. If you weie
you would know that you cannot test laudanum with less than an
ounce.
Witness : On the contrary, there is still quite sufficient in the
bottle for another analysis.
Alexander Spence and Joseph Tait proved the sale of laudanum.
Defendant said he had no witnesses. He denied that what he
sold was laudanum. The Pharmaceutical Society had been
watching him for two or three years to catch him selling poisons,
and he had refused them on two occasions before. The witness
Spence came to him for a bottle of castor oil and something
to relieve a pain, and he gave him something to the best of his
ability.
The Sheriff, having examined the bottle of laudanum, said
defendant had produced no evidence to show that what he sup¬
plied was not laudanum. It had been clearly proved that lauda¬
num was asked for, and he must also hold it proved that laudanum
was supplied. He therefore found the defendant guilty, and
imposed a modified penalty of £2 and £1 Is. of expenses.
The next case was against M. J. McArthur, assistant in the
shop of Dr. Lawson, at 506, Cathcart Road, Glasgow, who was
charged with selling laudanum and also cantharides as an ingre¬
dient in a blister dispensed by him on November 21, and a bottle
ofBudden’s “Balsam of Horehound and Coltsfoot” on November 28,
to two agents of the Registrar.
Mr. Brownlee, solicitor, appeared for the defendant, and said he
had also formally to tender the objections stated by Mr. Richardson,
although these had been repelled. He had also to state that
defendant had served a regular apprenticeship and had had con¬
siderable experience. He had also been up for his examination in
January, when he unfortunately failed in only one subject.
The defendant then pleaded guilty.
The Sheriff said he thought the plea that defendant had had
considerable experience was rather against him. He must be all
the better aware that what he had done was a dangerous and
242
PHARMACEUTICAL JOURNAL.
[March 13, 1897.
illegal act, and it was an aggravation of the offence to say that he
committed it with his eyes open. He therefore found him guilty,
and imposed a modified penalty of £1 for each of the three offences,
and £1 l.s. of expenses.
Other three cases were withdrawn by the prosecution.
Prosecution at Hamilton.
The case of Bremridge v. Miss Helen Robb, assistant in the
shop of Dr. Grant, at Blantyre, near Hamilton, came before Sheriff
Davidson in the Sheriff Court House at Hamilton, on Tuesday,
March 9.
The defendant, Miss Robb, assistant in the shop of Dr. Grant,
at Blantyre, near Hamilton, was charged with selling, on
November 3, to an agent of the Registrar a quantity of morphine
as an ingredient in a bottle of Kerr’s “Horehound, Honey, and
Tamarinds.”
Mr. Louden, of Archibald and Louden, solicitors, Hamilton,
instructed by Mr. P. Morison, S.S.C. , Edinburgh, appeared for
the prosecutor. Mr. Arthur Frame, of Hay and Cassels, solicitors,
Hamilton, appeared for defendant.
Mr. Frame said his client pleaded guilty. She had been for a
number of years engaged in doctors’ shops, but it was only about
eighteen month since she entered the shop of Dr. Grant. She
had never before sold patent medicines, and was not aware that
it was wrong to sell them in the way she had done. He was
also instructed to say that Dr. Grant intended to give up this
shop and supply medicines only from his own house. This was
the first case of this kind in the district, and he asked that a
small penalty only should be inflicted.
Mr. Louden said these proceedings were instituted, not for a
close corporation, but in the interests of the safety of the public.
The Sheriff : I am quite satisfied on that point. It is clear that
the Act is passed to secure the safety of the public.
Mr. Louden said he had to ask for the full penalty in this case, for
it was clear, at least, that Dr. Grant must know that his assistant
could not lawfully sell poison. There had been several prosecutions
for the sale of this very article in Ayr and at Greenock, and these had
been fully reported in the daily press. There had also been several
cases in Glasgow and at Airdrie. Though this article appeared so
innocent-looking at first sight, it really contained a powerful poison,
and had the evidence been called it would have been proved that it
contained sufficient morphine to be fatal to a child. Defendant
could hardly plead that she did not know it was a poison, but both
on the outside wrapper and on the label on the bottle it was stated
to contain poison, and to be therefore labelled poison. His Lordship
would see this from the bottle and wrapper which he now handed
\ o him.
The Sheriff, having examined the bottle and read the label upon
it, asked if there was no means of getting at the makers of these
proprietary medicines containing poisons, so as to compel them to
have more regard to the public safety in their distribution.
Mr. Louden said the Act only gave power to deal with the actual
seller. The action of the Registrar had compelled makers to label
these articles poison, but they did it in such a way as to make it a
mere technical compliance with the letter of the Act. It was not
rightly a compliance with the purpose of the Act.
The Sheriff said he thought it was a pity there was no power of
dealing with the maker. The name of this compound and the
appearance of the liquid were such as to lead any ordinary
member of the public to think it was a perfectly innocuous mix¬
ture. It was only after reading over the label very carefully that
one discovered, at the very end of a lot of printed matter, that it
contained such a deadly poison as morphine, and the word
“poison” occurred only in ordinary type in the body of the
printed matter, at the very end, and in such a way that it might
very readily escape observation. The labelling in this case seemed
to be done designedly so as to suggest that it was merely
technically poison, and that morphine was present in an infini¬
tesimal quantity. It appeared, however, that this compound with
such a dangerously tempting name — “Horehound, honey and
tamarinds ” contained sufficient morphine to be fatal to a child.
He thought it was distinctly contrary to the public interest that
these compounds should be sold in this way to the public, who, in
ignorance of their injurious properties, might use them indis¬
criminately. He regretted that the Act did not apparently give
power to compel the makers to label them in a prominent and
proper manner. This being the first case that had come before
him in this Court, he imposed a modified penalty of £3 with
£2 14. s. 4 d. of expenses.
PARLIAMENTARY NOTES AND NEWS-
The Petroleum Committee recommenced its meetings on
Friday, March 5, when Mr. Mundella was appointed Chairman.
The examination of witnesses was deferred till the following
Tuesday. Naturally the new Committee will have to consider the
evidence of its predecessors, and it is a curious example of Parlia¬
mentary procedure that the Chairman had to obtain an Order of
the House before the evidence of the Committees of 1894 and 189&
could be referred to the sitting Committee. We may, by way of
reminder, state that the task of the Committee is defined by the
terms of reference to be “ to inquire into the sufficiency of the law
relating to the keeping, selling, using, and conveying of petroleum
and other liquids, and the precautions to be adopted for the pre¬
vention of accidents with petroleum lamps.”
Companies Bill. — As was foreshadowed last week, Mr. H,
Lewis’ question, based upon the House of Lords’ decision in Sala
mon’s case, did not elicit any very satisfactory answer. The
Attorney-General, in reply, whilst expressing his sense of the
necessity for an amendment of the law relating to companiest.
showed his current knowledge of the Government efforts in tha,
behalf by wrongly naming the committee to which the Bill has
been referred. A Bill has already been introduced into the House
of Lords by the Board of Trade, said in effect, the honourable
and learned gentleman, and it is now before the Standing
Committee on Law. As a matter of fact, that Committee is a
House of Commons Committee, which is just now quite busy
enough with the Bill amending the Preferential Payments in
Bankruptcy Act, 1888. The select Committee, which is now
leisurely dealing with the Companies Bill, is a Lords Committee,
and has no connection with the Commons Standing Committee.
There does not seem very much ground for hope when the Crown
Law officers are so indifferent that they do not trouble to
accurately inform themselves of the progress of a Government Bill
on the subject.
Science and Art Department.— There appears to be a suspicion
that the administration of this Department is open to improve¬
ment — indeed, it is not the first time Parliamentary inquiry has
been urged and made into the way they do things at Kensington.
A Select Committee of fifteen members has now been charged to
investigate the question of the administration and cost of the
museums of the Science and Art Department. On that Committee
Lord Balcarres, and Mr. John Burns, Dr. Farquharson and Mr.
Bhownaggree, Sir J. Gorst, and Mr. Bartley find themselves asso¬
ciated, so that the public may be assured that the work will not be
carried out from one point of view only. Certain members of the
Committee have already shown their interest in their work by
writing letters to the Times, and Lord Balcarres has fortified him¬
self with the knowledge of how many previous Committees have
inquired into museums connected with the Department since
March, 1877.
Sir W. H. Dyke created some amusement by notifying that he
contemplated turning himself into a Light Railway Company
under last year’s Light Railway Act, and asking if he was likely to
be harshly dealt with in consequence. Sir Richard Webster re¬
plied that there was no connection between the two subjects, and
that Mr. Lewis had in his mind the raising of money by debentures
issued by trading companies which are really one man.
Weights and Measures. — The Government intends to intro¬
duce last year’s Bill legalising the use of metric weights and
measures. Mr. Ritchie has announced the fact, and considerable
satisfaction will be felt thereat in commercial circles.
Steresol as an Application to Sore Nipples. — Steresol forms
an admirable application to erosions of the breast. After washing
the parts with boric acid solution, a layer is applied, ten minutes
after a second coat is put on, and fifteen minutes later a third.
After the lapse of another quarter of an hour the nipple may be
used in nursing the infant. Steresol is absolutely harmless to the
child, and does not in the least affect the flow of milk. It acts as
a germicide and as a mechanical protective agent, preventing the
lips of the infant from touching the sore parts. — Bull. Gen. de
Therap. , cxxxii., 38.
March 13, 1897.] PHARMACEUTICAL JOURNAL. 243
LETTERS TO THE EDITOR.
On Counter Prescribing.
Sir, — In common, doubtless, with many others, I read with
interest your report of Dr. Macnaugh ton -Jones’ lecture before the
Chemists’ Assistants’ Association last Thursday week, and pro¬
bably his very judicious and friendly remarks concerning pharma¬
cists as a body and their relation to the medical profession will be
enerally endorsed, but the question of counter prescribing, which
e dealt with a,t some length, is one of considerable importance to
chemists, and it seems to me there is a side to that question which
doctors, as a rule, are inclined to ignore, and therefore, sir, with
jour permission (and you have never yet refused me the hospitality
of your columns on the rare occasions when I have sought it) I
should like to make a few observations, which seem to me not un¬
called for, seeing that the matter is one concerning the well-being
■of our craft itself, and if I trespass unduly upon your space I must
invoke your kindly consideration. All who are familiar with that
instructive and entertaining work, the ‘Progress of Pharmacy,’
will be aware that for centuries members of the different branches
■of the healing art have quarrelled among themselves almost
incessantly ; the jealousy and rivalry between physicians and
apothecaries, and subsequently between these latter and the drug¬
gists, together with the uncertainty of their respective rights and
privileges, are there very clearly and humorously described. I
fancy that even to-day peace and tranquillity do not pervade the
entire ranks of that august profession ; physicians feel aggrieved
that they are by a rigid etiquette prohibited from touching any¬
thing which ever so remotely resembles surgery, whilst their con¬
freres of the College of Surgeons practise medicine right joyously,
and scatter prescriptions right and left with a light heart ; the
rank and file, too, murmur grievously against the habit that is
largely increasing among people, who ought to know better, of
■combining together and securing medical attendance for them¬
selves and their families by a small monthly payment, instead of
“having the doctor,” as formerly, when occasion required.
Everyone, I think, admits the necessity for the revision and con-
solidation of the various Acts relating to the practice of medicine
(and may I add pharmacy), and possibly when Parliament can
spare a little time for useful and unpretentious legislation some-
thing may be done, nor will it be too soon, for surely there is no
other civilised country where such unblushing charlatanism exists in
so many forms.
All this may seem beside the mark, but it is distinctly germane
to the subject in hand, for there can be no doubt that notwith¬
standing the amiable remarks which distinguished medical men
from time to time permit themselves to make with regard to
chemists, as to the practice of pharmacy being an essential branch
of the healing art, and so on, the great majority of practitioners do
not so regard us. Now I am not going to discuss the relative
merits of doctors and pharmacists as individuals, though it might
be safely affirmed that in general culture and information the
latter would not suffer by a comparison with the former, but I say
emphatically that chemists have just as much right to complain of
doctors dispensing their own medicines (to say nothing of their
supplying in many cases all sorts of “sundries” and° medical
accessories) as the latter have to complain of counter prescribing.
I have heard it said, and so doubtless have many others, scores of
times, by various people — women as a rule — “Oh, my doctor is so
careful and takes such an interest in his cases, he always makes up
his medicines himself” (sancta simplicitas /). Occasionally one
has been tempted to point out that accuracy is far more assured,
and the risk of error greatly diminished, when medicines are
dispensed by a qualified pharmacist than when hurriedly put
together by a tired practitioner or his unqualified deputy. At
this time of day it is of course puerile to speak of “ the confidence
which exists between doctor and patient,” necessitating the
former being his own dispenser ; and indeed, theoretically speak¬
ing, it is idle to discuss the question at all, the interest and safety
of the patient are far more secured when the functions of pre-
scriber and dispenser are kept separate ; the latter acts as a very
necessary and salutary check upon the former, minimising error
and ensuring accuracy. The arguments in favour of this position
are too numerous and obvious to be mentioned, but there is one
which seems to me unanswerable, viz., that Great Britain is the
only civilised country in the world where the practice of doctors
dispensing their own medicines obtains ; the Englishman may lay
that flattering unction to his soul. All over the Continent the
position of medical men and pharmacists is clearly defined and
inviolably distinct ; even in Ireland they are far in advance of us
in this respect. It may be said, “but on the Continent pharmacists
do not prescribe,” true, but the answer is short and triumphant,
let doctors give up dispensing and chemists will soon drop
prescribing.
A few words as to doctors’ dispensing. A firm of surgeons with
an extensive practice often keep a dispenser, as likely as not a
promoted errand boy ; well and good, so long as he is qualified ;
and they supply, as well as medicine, such things as cod-liver oil,
malt extract, and all the various articles which come under the
name of medical accessories ’and surgical appliances. If doctors
desire to be traders, small wonder if chemists aspire to be pre-
scribers. Or take the ordinary G. P. , who has his hands pretty full
and does not keep either an assistant or dispenser, yet manages to
include the important function of dispensing in his multifarious
occupations. True his wife, if he is lucky enough to have one, or
other feminine assistance, may be available. There is a grim
humour about doctors’ dispensing that, to the initiated, is
extremely diverting. I am perfectly aware that certain excuses,
when any are thought necessary, are forthcoming for this practice
on the part of medical men, and four may be mentioned as being
perhaps the commonest. (1) That doctors cannot afford to give up a
lucrative part of their business, (2) that patients would not be willing
to pay a fee to both doctors and pharmacists, (3) that the wholesale
houses look up medical men so assiduously, supplying them with
stock mixtures, pills, etc. , thereby largely doing their work for them,
and (4) that in many parts of the country, where doctors are located,
there is no chemist. Now, of these, No. 2 may be at once dis¬
missed, as it is not to be supposed that this part of the work is given
in, at least with the better class, and with the poorer patients an
arrangement could easily be made with any neighbouring chemist.
In No. 1 we see readily the interest of the doctor, but not so easily
where that of the patient comes in. No. 3 is in my opinion almost
a fatal one, as that practice of having things cut and dried for
them is likely to make a medical man forget how to prescribe
altogether, and rely more and more on other people’s formulie to his
own and his patients’ detriment ; while if he does not happen to
have the drug which first suggests itself as desirable in any par¬
ticular case, he naturally enough uses something else. No. 4 seems
more valid on the surface, but as is the case in other countries, I
have no doubt that if the chemist got the dispensing, wherever there
was any dispensing to be had, a chemist would soon plant himself.
Of your patience, sir, indulge me a little longer, it is but rarely
that I trouble you, and the subject is one upon which so much
might be said. Now as to counter prescribing itself. Dr. Mac-
naughton- Jones admits the difficulty of avoiding it sometimes, and
in fact, as things are atpresent it is impossible. Let it be remembered
too, that counter prescribing is not illegal any more than doctors,
dispensing (the former may be inadvisable, and equally so the latter)
but when any and every journal takes upon itself to give medical
advice to, and prescribe for its readers, often in the most ludicrous
fashion, surely there is nothing unreasonable in an intelligent phar¬
macist, when asked to do so, giving suitable remedies for simple
complaints ; but, further, it is safe to assume that the practice is
wide-spread ; and yet, do we ever hear of any untoward result
from counter prescribing ? I rather fancy we should do so, and
promptly, were it called for ; a fatal error on the part of a medical
man in making up medicine would not necessarily become public,
but the unhappy chemist who overstepped the limits in pre¬
scribing (or for the matter of that, made a mistake in dispensing)
would hear of it and sharply. In any case, I wonder whether more
risk is incurred when a trained and skilled chemist prescribes over
the counter suitable and reliable medicines which his experience
has taught him to be indicated than when he hands over a bottle
of somebody’s “ universal elixir,” a never-failing remedy which a
benevolent government allows to be sold by all and sundry, pro¬
vided it bears a stamp.
Now, sir, let me say in conclusion that personally I do not favour
counter prescribing, and have done what I could in a small way to
discourage it. An experience of several years in different cities of
the Continent, as well as in dispensing establishments in England,
has convinced me that the functions of prescriber and dispenser
should not be combined ; but when I hear the unfortunate chemist,
who is ground beneath the upper and nether millstones of what
are practically doctors’ shops on the one hand, and the hopeless
inadequacy of the Pharmacy Act on the other, abused for counter
prescribing, I feel that there is something to be said for him, and
244
PHARMACEUTICAL JOURNAL.
[ If Arch 13, 1897.
that it ought to he said. My object in writing has not been, as
a superficial critic might suggest, to advocate the pecuniary and
selfish interests of the pharmaceutical body, but simply to demon¬
strate that if medical men usurp the functions for which the phar¬
macist, at great labour and cost, has especially equipped himself,
i.e., the preparation and dispensing of medicines, they must not be
surprised if chemists entrench upon a province which doctors
regard as their own, and do a little in the way of counter
pr escribing.
North Finchley, N., March 1, 1897. T. Edward Earrass.
Nitrate of Mercury Ointment.
Sir, — When discussing this preparation I think that the appear¬
ance and keeping properties of the ointment should be kept
separate from the question of acidity. Any pharmacist can judge
of the former, but the condition in which' the mercury exists after
the preparation of the ointment is, and has been, a disputed point,
and although several guesses have been made, not one of them has
been satisfactorily explained. In Mr. Maben’s letter, printed on
page 223 of the Journal, he remarks “the adoption of the suggestions
put forward by Mr. Squire would be a retrograde step. ” In one sense
it would be so, for the results of my experiments tend to show
that the instructions of the 1864 and 1867 editions of the BritishPhar-
macopoeia may be better than those of 1885. The earlier directions
read : “Dissolve the mercury with the aid of a gentle heat ; melt
the lard in the oil by a steam or water bath in a vessel capable of
holding six times the quantity ; and while the mixture is hot add
the solution of mercury, also hot, mixing them thoroughly. If the
mixture do not froth up, increase the heat till this occurs.” Now,
the latter sentence recognises the fact that the ingredients may
both be hot when mixed and yet not sufficiently so as
to cause effervescence, and this would be the case if the
temperature should not exceed 190° F., then the ingredients
would be further heated on a steam or water bath until frothing is
produced, which would happen before it reached 212° F. (100° C. ),
and chemical action having been started, the temperature would
rise rapidly to between 230° F. and 240° F. even on a water bath.
Now these are precisely the conditions which I have found to yield
the best results, and which are most easy to control, when the
Pharmacopoeia method of treating the lard and oil with the nitrate
of mercury is adopted.
There are one or two points in Mr. Maben’s letter which require
elucidation. He has “estimated the free nitric acid” in three
samples of ointment, and the figures given are 3 ‘78 per cent.,
3‘0 per cent, and 2‘1 per cent. One would like to know the
"process by which these figures were obtained, and the grounds for
assuming that the nitric acid was in the free state. In the case of
acid solution of nitrate of mercury none of the ordinary indicators
will distinguish between mercuric nitrate, and mercuric nitrate
with excess of nitric acid, and therefore the quantity of free acid
cannot be determined in the solution by direct titration.
When reading the first part of Mr. Maben’s letter, one is apt to
conclude that he recommended a temperature of 212° F. (100° C.)
or thereabouts, to which both the mercuric nitrate solution and
the fats should be heated before mixing, but later in the letter he
states that he prefers “ the ointment prepared at an initial
temperature of 300° F.” He also speaks of making several batches
at 300° F. to 350° F. This might convey the impression that both
the mercuric solution and the fats are heated to that temperature
before they are mixed, but I presume that is not so intended.
Immediately below this Mr. Maben remarks, “Mr. Squire thinks
it is important that the temperature should be kept as low as
possible after the addition of the mercuric solution. But here again
I (Maben) disagree. The temperature , should be sufficiently high
to cause free frothing after the mercuric solution is added.” But I
distinctly stated the conditions under which the ointment should be
made, and they include the free frothing aboj/e alluded to. “A
satisfactory ointment can be made by the latter method if the
temperature be kept as low as possible,” the latter method
described in my paper, resembles the B.P. process, but the
ingredients are mixed at between 80° C. (176° F. ) and 90° C.
(194° F. ) instead of 100° C. (212° F. ), and the mixture being heated
on a water bath, brisk effervescence ensues at the temperature
there given ; it is not 300° F. or anywhere near it, nor does any
further effervescence take place if the heat be increased to 300° F.
I have ascertained by experiment that the solution of mercuric
nitrate (made for the ointment as directed in B. P. 1885) boils at
about the same temperature as the nitric acid (250° F. ). I am,
therefore, quite at a loss to understand why 300° F. to 350° F.
should have been selected as the temperature for the process. It
is much above the boiling point of the mercuric solution, and there¬
fore nothing like so manageable as the lower temperature; it
also is quite unnecessary for the production of the brisk effervescence.
London, March 9, 1897. P. W. Squire.
ANSWERS TO QUERIES.
German Herb or Weed. — Probably Galium aparine, but you
should have sent a larger sample. [ Reply to W.B. — 83/24.]
Ink for Rubber Stamps. — Take of aniline violet or any other
soluble aniline colour, 2 drachms ; glycerin, 6 drachms ; methylated
spirit, 1 ounce ; gum acacia 6 drachms ; water 4 ounces. Dissolve.
[Reply to Kino. — 79/26.]
Herb used by Kaffirs. — This consists of the female flowers and
leaves of Tarchonanthus camphoratus (see Lindley and Moore,;
‘ Treasury of Botany,’ and Pappe, ‘ Flora Capensis Medica,’ 3rd.
ed., p. 22). [Reply to “ Ben Nevis.” — 83/7.]
Glycin. — This developing agent is one of a class of substituted
paramido-phenols, and is formed by the substitution of one of the
hydrogen atoms in the NHS group by an acetic acid residue, and is-
formed by the action of chloro-acetic acid on amidophenol, and it
has the formula C6H4OHNHCH2COOH, and is oxyphenylglycin.
[Reply to W. B. L. — 81/5.]
Ferridcyanide Reducer.— The action of the ferrideyanide in
the ferridcyanide and hypo reducer is first the formation of silver
ferrocyanide — 2Ag2 -+- 2K„Fe.(CN)]2 = Ag1Fe(CN)6 + K4Fe (CN)fi.
The silver ferrocyanide then dissolves in the hypo, forming silver
hyposulphite and sodium ferrocyanide. Ag4Fe(CN)s + 4Na2S 0->
= 4AgNaS203 = Na4Fe(CN)6. [Reply to W.B.L.— 81/5.]
Glycerin Cream for Chapped Hands, etc.— Bitter almonds,
1 oz. ; sweet almonds, 3 ozs. Bleach and beat into a paste with
3 drachms of almond oil and 2 drachms of powdered curd soap
gradually add 12 ozs. of rose water, and strain through double
muslin. To 3 ozs. of glycerin of borax add 1 oz. of spirit and 5 oz.
of any compound bouquet, such as opoponax, and 5 ozs. of water.
Mix this with the emulsion, and add more rosewater to make up
to 1 pint. [Reply to W. W. — 80/16.]
Acid Fixing Bath. — Theoretically, the addition of any acid
must decompose the hypo first, according to Seyerwitz and
Chicandard, into 2S02 ^OhU This would be decomposed into-
NcigSCXi -+■ H2S 4- SO, •+■ S, and the sulphurous acid would react-
with the hyposulphite, and form acid hyposulphite*
S°2 + HiS03 = 2NaHS03 + S. The H2S and SOa would
then react and form pentatliionic acid, 5H2S + 5S0.2 = 4H_,0 +
H.;S506 +S5. Still, if only sufficient organic acid is added to just
set free sulphurous acid, and yet leave sulphite in excess, the-
bath will not precipitate sulphur. This we have proved by trial.
[Reply to W. B. L. — 81/5.]
[Several Letters and Answers to Queries are un¬
avoidably held over, owing to pressure on our space.J
PUBLICATION RECEIVED.
Die Fabrikation der Kunstlichen Mineralwasser und-
anderer moussirender Getranke. By Dr. B. Hirscii and-
Dr. P. Siedler. 3rd. Edition. Pp. 393. Price 8s. Brunswick .
Vieweg und Sohn. 1897.
OBITUARY,
Laws.— On March 1, John Laws, Chemist and Druggist,,
Marylebone. Aged 84.
Cupit. — On March 6, Alfred Cupit, Chemist and Druggist, New
Brampton, near Chesterfield. Aged 70.
COMMUNICATIONS, LETTERS, etc., have been received from
Messrs. Austin, Bird, Churchill, Coleman, Coull, Cowley, Cracknell, Duncan,,
Elliott, Farr, Fitch, Forret, Gibson, Goodall, rGrier, Jlcap, Hill, Hogg, Holmes,,
Ingham, Johnson, Johnston, Jones, Keen, Kemp, Kennedy, Kerr, Marsden.
Matthews, Miller, Naylor, Owen, Parsons, Pickering, Pollard, Smith, Squire-/
Tallis, Turner, Umney, Williams.
PHARMACEUTICAL JOURNAL
245
March 20, 1897J
r%*5i
IYING&B0X FOR PILLS, ETC.
1 35- f
J 'J‘ "•
« Corresponding Member of the Pharmaceutical Society.
V _a. N. : 1 *—~ ,> ■if. M
y.In a, recent is^ue^ the Journal (see last volume, p. 546) a
description is giyeri of a convenient drying-box suitable for phar-
maceuticlu purposes, in which lime is used as the desiccating
agent. For nearly three years past a similar drying-box has been
used in the Bengal Medical Store Depot with considerable’ advan¬
tage. Working in Calcutta for many months in the year with air
fairly well saturated with moisture, it is necessarily a matter of
difficulty to dry preparations by exposure to air. A teak-wood box
was accordingly constructed, lined with tin, and fitted with two lids,
the inner one being coated along its sides with felt and resting on
ledges similarly fitted, like the inner lid of an ice chest. At the
bottom of the box a movable tin tray was placed, which contained
a charge of about 25 lbs. well-burned lime in small lumps, the sub¬
stances to be dried being placed in perforated zinc trays, supported
by battens over the lime.
A desiccating material is perhaps better adapted for drying
pills, even when volatile oils are absent, than a current of warm
air. If heat be employed the pill is heated throughout, and there
is a tendency for the mass to become uniformly hard. When a
drying agent, however, such as lime, is used, it is probable that as
the surface is first desiccated, and becomes hard', moisture from
the interior of the pill is with difficulty expelled, and a more easily
soluble pill is the result.
Obviously for pills containing volatile oils, etc. , the drying-box
is incomparably superior to desiccation by exposure to air. In
drying pills containing camphor, or volatile oils in the drying-box,
the following expedients might also be advantageously adopted to
still further save loss from volatilisation. Place in the drying
box a shallow dish containing the volatile oil, etc. , present in the
pill. The air span of the drying box would consequently be
rapidly saturated by the easy evaporation of this oil, etc. , and loss
from the pill mass checked.
COMMERCIAL GINGERS AND ESSENCE OF GINGER.*
BY W. S. GLASS.
With the object of obtaining a satisfactory essence of ginger,
Jamaica, Cochin, and African ginger have been experimented with,
and the following table gives the percentage results of the examina¬
tion, the results as regards oleo-resin, obtained by Thresh (‘Year-
Book,’ 1879, p. 438), Frank and Siggins ( Proceedings Amer. Phar.
Assoc., 1888, p. 311), and Riegel (‘Year-Book,’ 1892, p. 168), being
quoted for comparison
Author.
Thresh.
Frank and
Siggins.
Riegel.
Jamaica .
Cochin .
African .
Moisture.
9-33
11-00
8-00
Ash.
5-3
4- 6
5- 5
Extract
or
oleo-resin.
5- 00
4-33
6- 33
Extract
or
oleo-resin.
3-290
4"965
8-075
Extract
or
oleo-resin.
5-00
(A 6-17
1 B 7-00
Extract
or
oleo-resin
5
The extract was prepared by exhausting 300 grains of ginger
with ether and evaporating at a low temperature till a soft,
resinous mass remained, possessing in a high degree the pungent
and aromatic odour and taste of ginger. The African variety
required most ether, and yielded a higher percentage of extract.
It will be seen that the results obtained differ from those of
Thresh, and correspond with those of Frank and Siggins and
Riegel. It may be concluded, therefore, that while African ginger
* Read at an Evening Meeting in Edinburg-h.
Vol. LVIII. (Fourth Series, Yol. IV.). No. 1395.
is unsuitable for many pharmaceutical purposes on account of its
brown, coarse appearance, it yields the highest percentage of oleo-
resin and the strongest essence. A soluble essence possessing all the
flavour of the ginger can be readily prepared by adding to 1 fluid
ounce of the essence 3 drachms of powdered pumice-stone and
shaking occasionally during twelve hours. Then add gradually
3 fluid ounces of distilled water, shaking after each addition ; let
stand for six hours and filter.
NOTE ON A SAMPLE OF SCAMMONY.*
BY I. W. THOMSON.
Some time ago a parcel was handed to me marked “ Scam-
monium,” accompanied by a statement that it contained 84-864
per cent, of scammonin, and that there might be no mistake, gave
the chemical formula, which is generally accepted as representing
that body, C33H66014. It was said to be of German origin.
A very cursory examination of the sample so completely belied
its certificate of character that I concluded it could hardly claim
more than a very remote relationship with scammony.
Having mentioned the circumstance to Mr. Hill, he suggested
that I might exhibit the sample and submit the result of my
examination of it at an evening meeting.
The sample consists of irregular broken pieces, apparently
portions of a cake, about half an inch in thickness, greenish-black,
hard, and horny, breaking with a resinous fracture, and very
difficult to powder. On submitting it to a systematic examination
the following results were obtained : — •
I Soluble in ether . 0-4 per cent.
,, ,, alcohol . . . . „ . 20 „
„ „ water . . . 420 „
Starch and a little cellular tissue . 43 "0 ,,
Moisture . 12 '0 ,,
100-0
It yielded 2T2 per cent, of ash, of which 0'93, equal to 43-6 per
cent., was soluble in water. The ash contained K, Mg, Ca, Fe,
and Si, as carbonate, sulphate, and a trace of chloride.
The water-soluble portion was evidently gum, apparently gum
arabic. The insoluble portion consisted very largely of starch,
with a small quantity of cellular tissue.
So far as I know the specimen is unique, and the Germans must
think us very gullible when they attempt to foist such an article
upon us as scammony.
CONTRIBUTION TO THE KNOWLEDGE OF STRYCHNINE
DRUGS.t
BY G. SANDER.
Herr Sander has investigated the nature of strychnic or igas-
uric acid and the different methods for the determination and the
separation of strychnine and brucine, as many varying and con¬
tradictory statements have been made on this subject.
The acid existing in the official strychnine drugs, A ux vomica
and Fabae St. Ignatii, has been generally described as “ igasuric
acid,” and the plant bases as existing in the drug as igasurates.
Although igasuric acid has been regarded as a form of
tannic acid, it has not been ascertained to which class o
tannins it belonged. In order to obtain further information
respecting this acid, Herr G. Sander prepared in the first instance
some purest possible material. The pure acid was obtained by
fractional precipitation of a cold alcoholic extract with lead
* Read at an Evening Meeting in Edinburgh.
t Inaugural dissertation from the Pharmaceutical Institute of the University
of Strasburg ( Archiv der Pharm., 235, 2, 133).
246
PHARMACEUTICAL JOURNAL.
[March 20, 1897
acetate, and the lead precipitated decomposed with sulphuretted
hydrogen. The acid so prepared was an amorphous brownish-
yellow substance, which could be easily rubbed down and powdered.
The acids obtained from both drugs appear from many agreeing
reactions to be identical. A series of reactions with ferric chloride,
lead acetate, silver nitrate, bromine, etc., pointed to a marked
agreement with caffetannic acid. When the “igasuric acid” is
treated with potash it is split up into another acid with formation
of a sugar. This acid proved to be caffeic acid. The so-called
igasuric acid is then nothing more than caffetannic acid, but
whether the alkaloids exist in the drugs in combination with this
acid must remain for future investigation.
The various methods for determination of the total alkaloids in these
drugs — dependent upon precipitation with Mayer’s reagent, potassic
ferrocyanide, tannic acid, or on titrating with acid the residuary
alkaloids extracted by solvents — are unsatisfactory. The titration
value of the two alkaloids strychnine and brucine being different,
■correct results are only to be obtained when the proportion of the
two alkaloids in the mixture is known. A method must therefore
be sought that should give a pure alkaloidal residue which could
be weighed as expressing accurately the amount of the total alka¬
loids. Keller’s process was found to be the best to give a pure,
white crystalline alkaloid without any admixture of impurity, and
this process he adopted.
For the determination of the relative proportion of the two
alkaloids, he obtained very satisfactory results by the method
-which consists in destroying the brucine with potassic perman¬
ganate and estimating the strychnine by difference.
Sander in this way has found there is a constant proportion in
the amount of stiychnine and brucine existing in these drugs. In
nux vomica and its preparations the percentage of strychnine in
the total alkaloids varied between 43 ‘9 to 45 ’6, and this cor-
• responds, for the higher figure, to a mixture of one molecule of
strychnine with one of brucine.
In St. Ignatius beans the proportion of strychnine is from 60 -7 to
'62 -8, and for 62 '9 this gives a ratio of one molecule of brucine to
two molecules of strychnine.
It is, therefore, probable that in both seeds the alkaloids exist in
a simple constant proportion.
PRACTICAL RADIOGRAPHY.
V.— PLATES AND SCREENS.
Notwithstanding the many trials which have been made to
•determine the most suitable plate for radiography, we seem as far
•off as ever from obtaining any satisfactory definite results. In
•some hands the best results have been obtained on extremely rapid
plates, whilst in others slower plates have yielded better results.
At present there seems to be no definite relation between
the sensitiveness of the plate to daylight and the X rays.
Several firms of plate makers have placed special plates on the
market for X ray work, and in our hands all have given good
results. They are the Cathodal plate of the Imperial Dry Plate
Company, of Cricklewood, the Rontgen plate of the Sandell Works
Company, Thomas’ Cathode plate, and Edwards’ Cathodal plate.
The latest introduction in this way is the X ray paper of the East¬
man Photographic Materials Company, and whilst this has been
proved to be quite as quick as plates, it has thp advantage that
each sheet is packed in a black envelope all ready for use. Another
advantage of this paper is that it can be bandaged round a limb,
and, therefore, closer contact ensured with the body. It must not be
forgotten, too, that the results obtained with this paper show the
bones white on a black ground, and therefore there is no need to
print from them again, and further, though this applies, of course,
to plates as well, that a dozen or more envelopes may be placed
one on top of the other and prints obtained on the twelve at once,
which for lecture purposes is an advantage.
There is only one special point in connection with the development
of radiographs, and that is that the development must be pushed a
great deal further than is the case with ordinary negatives, and so
far the best results have been obtained with metol and hydroquinone,
which is rapid, gives good density, and does not stain.
Fluorescent screens may be bought commercially, but for those
who wish to make their own the following directions may be useful.
The salt most generally used at the present time for making the
screens is platino-cyanide of barium, which is not only expensive,
but which differs considerably in its fluorescent properties, which
depend to some extent apparently on its crystalline form. As far
as possible the crystals should be uniform in size, and a sheet of
Bristol board of the required size should be coated with enamel
collodion, made by dissolving 7 grs. of pyroxylin in § oz. of ether and
A oz. of alcohol and dusting the platino-cyanide over the collodion
whilst still tacky. The best way of doing this is to place it in a chip
box with the top knocked out and a piece of not too fine muslin
stretched over the top by means of the rim lid. As even
a coating as possible should be given, and the screen should
be uniformly yellow.
The finest platino-cyanide can be obtained from C. A. Kahlbaum,
Chemische Fabrik, Schlesischestrasse 35, Berlin S.O., who has
prepared a special form for radiography. Other firms, other than
English manufacturers, Avhom it is not necessary to mention, are
Chemische Fabrik auf Aktien, Miillerstrasse 170, Berlin N., E
Merck, Chemische Fabrik, Darmstadt, and Dr. Schuchardt, of
Gorlitz.
Calcium tungstate, so strongly recommended by Edison, has
proved much inferior in our hands to the platino-cyanide, and
this is said to be due to the difficulty of obtaining it of the proper
crystalline form.
Melckebeke’s double fluoride of uranium and ammonium, de¬
scribed in the last volume of the Journal, at page 366, is almost as
good as the platino-cyanide, but it is better to crystallise it in a
dish, and then dry and powder on to the screen rather than crystal¬
lise on the card direct, as was suggested by the authors.
Within the last few days it has been stated abroad that opal
glass makes a far better support for the fluorescent salts than card,
but this seems somewhat anomalous, as glass certainly stops more
X rays than card.
To conclude, in giving the followTing addresses of firms who supply
tubes and coils, it must be distinctly understood that only actual
manufacturers with whom the writer has had dealings are men¬
tioned, but there are doubtless many more who can supply all that
is required equally well. For induction coils : — W. H. Cox, Cursitor
Street, Chancery Lane, E.C. ; S. Bottone, Electrician, Wallington;
F. S. Allsop, 97, Queen Victoria Street, E.C. ; King, Mendham
and Co. , Bristol ; Schmidt and Haensch, Berlin ; Siemens and
Halske, Berlin; Gaiffe and Cie, Paris; Hurst and Co., 53,
Leadenhall Street, E.C. For tubes : — Cossor, 67, Farringdon
Road, E.C. ; Miller, Gray’s Inn Road ; Hurst and Co., J. J. Hicks,
8, Hatton Garden.
To Fasten Metal to Glass. — A suitable cement is obtained
by boiling 3 parts of colophony and 1 part of soda in 5 parts
of water. Of the resulting soap 50 parts are well mixed with
100 parts of gypsum. When dry, this cement is said to be
perfectly impenetrable to fat oil and petroleum.— Pharm. Zeit-s. f.
Bliss., xxxv., 861.
March 20, 1897.]
PHARMACEUTICAL JOURNAL.
247
THE PLOUGH COURT PHARMACY.
( Concluded from page 167.)
At the time William Allen and Luke Howard entered into part¬
nership, chemistry was beginning to undergo the great change
inaugurated by Lavoisier, and the application of chemical know¬
ledge in various branches of technical art was attracting general
attention, either in actual practice — as in the use of chlorinated
alkaline liquors for bleaching — or experimentally, as in the
extraction of alkali from common salt, and the production of gas
for illuminating purposes.
Both the partners in the Plough Court firm were then
young men of twenty-seven and twenty-five, so that the
stimulus of youthful enthusiasm as well as the remark¬
able scientific developments of the period when they com¬
menced their joint business career, can well be understood to
have exercised considerable influence upon them during the con¬
tinuance of the partnership, which lasted for several years.
It is, however, difficult at the present time to realise what must
have been the position of a manufacturing chemist in 1797, or to
comprehend, without some reflection, how limited was the range of
his operations and how much his work was beset with difficulties
which are now scarcely conceivable. At that time chemical
industry was confined to the production of soap, the mineral acids,
and some saline compounds then used in medicine. Among the
latter, mercurial preparations held an important place, and some of
these appear to have first received attention by the firm of Allen
and Howard. The early laboratory account books of the firm men¬
tion ammoniacals, caustic potash, borax, argentic nitrate, and cream
of tartar, as well as ether, benzoic acid, and refined camphor, which
were then articles of the materia medica, citric, tartaric and oxalic
acids, etc.
About the year 1804 the laboratory was removed from
Plaistow to larger premises at Stratford, and in 1807 the
partnership was dissolved, William Allen continuing the retail and
dispensing business in Plough Court, while Luke Howard retained
the manufacturing laboratory at Stratford as a separate concern.
Notwithstanding much anxiety with regard to the responsi¬
bilities of an extending business, Allen had steadily continued the
study of chemistry and natural philosophy. He had been elected
a member of the Physical Society at Guy’s Hospital, had assisted
in the formation of the British Mineralogical Society, and regu¬
larly took part in the proceedings of the Askesian Society, as
shown by the following entries.
1800. 28th January.—" W. H. Pepys making experiments for the new gas
from nitrate of ammonia, for the Askesians. Lecture, Mr. Bradley.
Atkesian Society — many visitors. Tupper and I breathed the gaseous
oxide of azote. It has a remarkably inebr'ating effect.”
27th February. — “ Experiments on respiration. Present : — Astley
Cooper, Dr. Bradley ; Allen, of Edinburgh ; the two Lawsons ; and J.
Fox. We all breathed the gaseous oxide of azote. It took a surprising
effect upon me, abolishing completely at first all sensation ; then I had the
idea of being carried violently upward in a dark cavern with only a few
glimmering lights. The company said my eyes were fixed, face purple,
veins in the forehead very large, apoplectic stertor, etc. They were all
much alarmed, but I suffered no pain, and in a short time came to myself.”
About that time Allen became a member of the Royal Institution
and a note in the diary shows that he attended the opening lecture
in March, 1800. In the following year, when Humphry Davy — the.
Penzance apothecary’s apprentice — had been drawn from the
“ scientific aberrations ” of Dr. Beddoes’ Pneumatic Institution to
become Professor at the Royal Institution, the interest attaching to
him led Allen to be present with his friends W. H. Pepys and
Richard Phillips, at Davy’s first lecture on galvanism. This lecture
Allen describes as “ a most capital one,” predicting also that Davy
"bids fair to rise high in the philosophical world.” Subsequently
Allen became intimate with Davy, and closely associated with him
in the work of the Royal Institution.
Botany was also a subject to which William Allen paid attention,
and in the summer of 1801, after an excursion in Essex, he speaks
of having had a rich feast of botany with his friends L. Dillwyn
and J. Woods, looking over the specimens he had collected, and of
having found one very good thing — the Juncus acutus. He had
for some time past been delivering lectures on chemistry at Plough
Court, and at one of them he mentions having had an audience of
sixty, including among the number Dr. Relpb, Astley Cooper, Dr.
Bradley, and T. Poole.
Allen’s scientific work was then attracting much notice, and he
was frequently called upon to make chemical analyses or to conduct
experiments requiring skill and accuracy. The Plough Court es¬
tablishment also became celebrated as a repository of chemical
reagents, to the preparation of which Allen had directed his atten¬
tion with much success. A collection of them was exhibited at the
National Institute, in Paris, by Professor Pictet, of Geneva, and
attracted particular notice from the chemical members.
Towards the end of 1801 there is a note of a visit with W. H. Pepys
to the Royal Institution, where Davy showed them “ a fine experi¬
ment of Dr. Wollaston’s, in which common electricity is seen to
decompose water like galvanism,” and another of the deflagration of
charcoal.
In the following year Allen was invited by Dr. Babington to join
him in delivering lectures on chemistry at Guy’s Hospital, a pro¬
posal which he accepted on the earnest recommendation of Astley
Cooper. His first lecture there was delivered on February 13,
and there is the following note in reference to it.
•Rose early— getting ready for experiments at the Hospital. I felt dis¬
tressingly low and anxious— gave my first lecture there, at which Drs.
Babington and Curry were present, and Astley Cooper came in. I got
through much to my satisfaction and apparently to that of the class. It
began and ended with loud plaudits/'
Allen was at this time in frequent communication with Davy, he
was elected a President of the Physical Society at Guy’s Hospital,
and in 1803 took part withDrs. Lettsom, Bradley and Pole inform¬
ing an institution for cow-pox inoculation. During that year he
describes a botanical excursion with several friends. After
breakfasting at Harrow they set off on foot over the cornfields to
Morpeth Field, after the Fritlillaria without success ; but found
the Helleborus viridus a scarce plant in those parts, the Ophio-
glossum and Vinca major; they dined at the Kings Head, Harrow,
and set off home at six.
In a note dated July 4, 1803, reference is made to the following
letter from Davy inviting Allen to deliver a course of lectures at the
Royal Institution.
Dear Allen,
Our managers have formed a plan of instituting different lecture on
parts of natural philosophy in the next season.
The terms will be liberal. Would you like to deliver in the theatre of
the Institution the course on natural philosophy that you have given
at Guy’s? Think about it, and let me know what your feelings
are. I should have called on you, but I have been ill, and am not yet
well. I go out of town to-morrow.
I am, dear Allen, with very great regard, yours, H. Davy.
A few days later John Dalton, of Manchester, visited AlleD, haviDg
been one of those requested to lecture at the Royal Institution, and
they discussed the matter.
Sympathetic mention is here made of the accidental drowning
248
PHARMACEUTICAL JOURNAL.
[March 20, 1897
of Jonathan Middleton, who had been for several years one of
Allen’s assistants at Plough Court.
In the same year there are notes of interviews with the Com¬
mittee of the Royal Institution on a subject of lectures, of a dinner
with Hatchett and Davy at Hammersmith, the discussion of a
paper by Tilloch on Electricity at the Askesian, and on Dalton’s
introductory lecture at the Royal Institution that “ he appeared
too much depressed with a sense of the audience.” Allen’s own
lectures in the following year do not appear to have been quite
free from a similar influence.
1804. 24th January. — '■ Set off between eleven and twelve for the Royal
Institution to give my first lecture— introductory nd the general pro¬
perties of matter— felt much at presenting myself before such an
audience, but got on exceedingly well ; Hatchett and Sullivan came to
me after the lecture, and many expressed their gratification.”
The lectures were, however, successful, and Allen was requested
to deliver another course in 1805.
In the course of the next two years William Allen visited Corn¬
wall and Cambridge, where he was courteously received by several
of the professors and heads of Colleges.
In August, 1805, serious alarm was caused by an outbreak of fire
at Plough Court, caused by the breaking of a bottle of nitric acid
which did considerable damage before it was extinguished.
The following year Allen married Charlotte Hanbury, and then
took up his residence at Stoke Newington. The work connected
with the slave trade took up much of his time up to the passing of
the Bill for abolition in 1807, but scientific work was continued, and
notes in December, 1806, record attendance at the Royal Society, when
Davy’s paper on “ Decomposition by Galvanism ” was read, as well
as the commencement of experiments with Pepys on the combus¬
tion of charcoal and respiration, which were continued for some
months. In March, 1807, Davy was ill, and at his request Allen
delivered a lecture for him at the Royal Institution “ under very
difficult circumstances, as the audience had been given to expect
new discoveries.”
In the arrangements for chemical lectures atGuy’s Hospital, Dr.
Marcet was now associated with Dr. Babington and William
Allen. The first part of the paper on Diamonds was read at the
Royal Society in June, 1807.
In the following November Allen assisted, together with Davy,
Dr. Babington, and several others, in the institution of the
Geological Society at a dinner at the Freemasons’ Tavern. A few
days later a visit to the Royal Institution with Pepys is recorded,
when Davy showed them “ his new experiments on the decompo¬
sition of potash and soda,” by which oxygen was driven off, and
“ a new substance produced, in little globules, which has the
properties of a metal.” He adds : “ Pepys and I concluded we
would cheerfully have walked fifty miles to see the experiment.
Here is another grand discovery in chemistry.” In the same
month Allen was elected a Fellow of the Royal Society, and
admitted after introduction by Sir Everard Home, the surgeon.
Shortly after the Act for the Abolition of the Slave Trade
received the Royal assent, Allen attended a meeting of the Friends
of the Civilisation of Africa, at which the Duke of Gloucester pre¬
sided, and “The African Institution” was formed. Wilberforce,
Lord Spencer, Roscoe of Liverpool, and Owen, Chaplain to the
Bishop of London, spoke, and thanks were voted to Wilberforce,
Granville Sharp, the Royal Duke and T. Clarkson. “ It was a most
satisfactory meeting — several bishops were there.”
An entry on April 12, 1808, records a visit with Luke Howard to
Basil Montague, in Lincoln’s Inn, where they met Frederic Smith,
and inaugurated a society “ to diminish the number of capital
punishments.” Another in May relates to the paper on respiration.
11 Pepys and I want up to Davy with it on seventh day ; he finds it hard work
to give up his favourite idea ot the absorption of azote ; he, however, seems,
though reluctantly, to yield to the evidence of our experiments ; this is quite
as much as we could expect, seeing it overturns almost all his experiments on
this subject ’
Another interesting note on June 30 describes the reading of
Davy’s paper on the decomposition of the earths, when mention was
made of the “ information from Berzelius, of Stockholm, as to the
decomposition of ammonia by galvanism, showing that it also has
metallic properties.” Later in the year Allen, together with Davy
and Pepys, visited Children at Tonbridge, to experiment with a
large galvanic battery, and in November he wrote to Davy declining
to continue the lectures at the Royal Institution. In June, 1809,
the second paper on respiration was sent to the Royal Society, and
subsequently Allen received from John Dalton, of Manchester, the
following letter relating to it
“I have read with great interest your two papers on carbonic acid and
respiration, and upon the whole am very well pleased with them. I
wrote a paper two or three years ago on respiration, which will perhaps
appear in our next volume. The results of my experiments led me to
conclude that all the oxygen which disappears is to be found in the car¬
bonic acid : there is one very striking difference in our experiments— the
medium of air respired with me, loses only four or five oxygen per cent, and
gains nearly the same acid, the conclusion you obtain from respiring the
same air as long as possible is very remarkable— I cannot make up my mind
upon it. I was glad to see your results on charcoal, etc., so clear and
definite.”
In July, 1813, Allen, together with Wilson Lowry, and Dr. Thomp¬
son, again visited Children at Tonbridge, where they found a great
assemblage of English chemists, including Wollaston, Tennant,
Davy, Hatchett, etc. and carried out a number of experiments. On
April 16, 1814, an entry shows that in the twentieth lecture of the
course at Guy’s, Allen “ showed iodine for the first time,” and within
six months after the announcement of its discovery by Courtois at a
meeting of the National Institute of France. Another entry in
November shows that he had been elected a member of the Royal
Society Council.
The courses of lectures on chemistry and natural philosophy at
Guy’s Hospital were continued by Allen for twenty-five years, but
the difficulty of the work under the pressure of other engagements
was often referred to incidentally in the diary. Chief among these
were the various philanthropic undertakings with which Allen was
connected. In the course of 1808 he became associated with
Joseph Lancaster in the educational work which had then been
carried on by him for some few years under the patronage of Lord
Somerville, the Duke of Bedford, and subsequently of the King
and several members of the Royal family. Owing to deficient
capacity for business management of his enterprise, Lancaster had
become involved in serious financial embarrassment, which compelled
him to place his affairs in the hands of a committee consisting of
Joseph Fox, William Allen, John Jackson, Joseph Foster, William
Carston, and Thomas Sturge. In the prosecution of this work much
time and labour were given by Allen to the keeping of regular ac¬
counts, and when the Lancasterian Institution was formed in 1812, his
acceptance of theoffice of treasurer threw upon himadditionalrespon-
sibility. While thus occupied Allen was brought into communication
with the Duke of Kent, who was an active supporter of the Lancas¬
terian Schools, and took part in the formation of the British and
Foreign School Society in 1814. About that time Allen was con¬
sulted by the Duke as to his private affairs, and in consequence of
the advice given by him as to needful retrenchment, Allen became
trustee of the Duke’s estate during his absence abroad ; he was thus
the means of rendering a service which was acknowledged by the
Duke of Kent in very gratifying terms. Our Queen has never for-
Mabch 20, 1897]
PHARMACEUTICAL JOURNAL.
249
gotten the kindness done to her father, and has on many occasions
shown her respect and affection for the Society of Friends.
Shortly after Allen’s intimate association with the Duke of Kent
he was introduced to the Emperor of Russia and the KiDg of
Prussia when they came to London in 1814, after the abdication of
Napoleon Buonaparte. Very remarkable religious intercourse
resulted, especially with the Emperor Alexander, which was main¬
tained subsequently when Allen paid long visits to Russia and other
continental countries. During one of these visits in 1816 Allen’s
wife died at Geneva. Eleven years later, and soon after the death
of his daughter, Allen married again, Mrs. Grizell Birkbeck, and in
writing to a friend, communicating his intention, he said, “ Should
this step appear singular, let it be remembered that the despensations
through which I have had to pass, have been singularly afflictive.”
In 1836 he again became a widower.
establishment of Messrs. Allen and Howard as an apprentice and,
in the course of a few years, he had acquired an important position in
the business, eventually becoming a partner. Under his direction the
pharmacy was re-arranged in accordance with the great improve¬
ments resulting from general scientific progress during the latter
part of the eighteenth century, and the following entries in Allen’s
diary show that in 1813 the management of the business was
almost entirely in Barry’s hands : —
January. — “John Barry took stock without me — this is the first time for
nineteen years that I have not been actively engaged in it.”
„ 29. — “This month has been a very busy one, but John T. Barry
has taken almost the whole weight of the business off me.”
Besides carrying out a complete re-organisation of the estab¬
lishment, Mr. Barry introduced, among other improvements,
the use of angular bottles for keeping such poisons as were admitted
Another very onerous undertaking in which Allen was concerned
was the industrial establishment of Robert Owen, at New Lanark,
with which he was connected for twenty-two years, and it gave him
much anxiety on religious grounds. The establishment of an
agricultural colony at Lindfield, in Sussex, about 1821, was a source
of greater satisfaction. Writing of this colony in 1830, Allen says : —
“ My object in taking Gravely Farm was to prove, by an experiment under
the public eye, that it is possible to render the agricultural labourer inde¬
pendent of parish relief, even with his present very low wages, by letting
him have a little land upon fair terms, and directing him in the cultivation
of it. This experiment has succeeded.
Since the dissolution of the partnership with Luke Howard, in 1807,
the entire responsibility of the Plough Court business had devolved
upon William Allen and, with the increasing demands of his other
occupations, the need of assistance was no doubt felt.
About the year 1 804 J ohn Thomas Barry bad entered the Plough Court
upon the dispensing shelves. A method devised by him for pre¬
paring extracts in vacuo attracted considerable attention. In addi¬
tion to his various scientific and pharmaceutical pursuits he was
closely associated with William Allen in philanthropic work and
took a very active part in the endeavours to obtain abolition of
capital punishment, being largely instrumental in bringing about
an alteration of the law in that respect.
The rearrangement of the pharmacy then carried out by Mr. Barry
is represented in tbe accompanying illustrations.
The marriage of William Allen with Charlotte Hanbury in 180 6
had also led to occupation being found at the Plough Court estab¬
lishment for his wife’s nephews, Daniel Bell Hanbury and Cornelius
Hanbury, and the management of the business soon devolved upon
them, together with John Thomas Barry, under the style of Allen
Hanburys and Barry.
There is yet to be recorded another phase of William Allen’s
250
PHARMACEUTICAL JOURNAL.
[Maeoh 20, 1897
active life which is of especial interest to chemists and druggists.
The chaotic state of affairs prevailing in regard to the practice of j
medicine and pharmacy at the end of the last century, in conse¬
quence of the absence of authoritative qualification for the exercise
of either occupation, had become as prejudicial to those so ;
engaged as it was to the general public.
There was then no provision for medical education beyond
apprenticeship and attendance at the lectures of private teachers,
or at the hospitals. The physician’s degrees granted by the Univer¬
sities of Oxford, Cambridge, and Edinburgh — the only recognised
qualifications — were taken by very few, and the Society of Apothe¬
caries was still without power to confer qualification to practise
medicine. But the growing importance of apothecaries as medical
practitioners throughout the kingdom and the want of a competent
jurisdiction to restrain ignorant persons from practising, naturally
directed attention to the necessity of establishing a legal qualifica¬
tion on the basis of systematic education. Under the leadership of
Mason Good, George Mann Burrows, Robert Upton, Anthony Todd
Thomson, and other apothecaries engaged in medical practice, an
organisation was formed, with the title of The Associated Apothe¬
caries, in order to obtain the necessary reform. The attempt to
provide a remedy was not confined to the practice of medicine, but
was also intended to have the effect of regulating the practice
of pharmacy, so that chemists and druggists would thus have been
subjected to the control of the apothecaries. The fundamental
principle that educational training and legal qualification were
essential for the pharmacist as well as for the practitioner of medi¬
cine, was reasonable enough ; but the chemists having acquired by
long usage a prescriptive right to the practice of pharmacy,
objected to being placed under the control of the authority which
the apothecaries proposed to establish for regulating the practice
of pharmacy as well as their own medical practice.
When the Associated Apothecaries endeavoured, in the early part
of the present century, to obtain legislative regulation of the practice
of medicine and pharmacy, some provisions of the Bill introduced
into Parliament with that object were considered by chemists and
druggists to threaten the position they had then acquired as com¬
pounders and dispensers of medicine. At a public meeting of
chemists and druggists held on March 4, 1813, and presided
over by Mr. Hudson, of the Haymarket, a committee was ap¬
pointed to take steps for opposing the Bill. William Allen was a
member of that Committee, and its first meeting was held at his house
in Plough Court on March 5, 1813. The following entries in the diary
are interesting and show that no time was lost.
6tli March. — “ Called on Wilberforce, Whitbread, etc., on the Apothe¬
caries’ Bill. This is a new cause of anxiety, and much of
the labour of opposing it will devolve upon me.”
15th. — “ Globe, Fleet Street, 4 o’clock, committee on Apothecaries’ Bill.”
29th. — " Apothecaries Bill withdrawn on account of opposition.’
The energetic action then taken led to temporary withdrawal of
the Bill ; but in view of the fact that it was to bs again introduced,
the Committee was made a permanent committee for the future
protection of the interests of chemists and druggists, William Allen,
W. B. Hudson, and Edward Horner being appointed trustees of the
fund raised for the purpose.
During the next two years negotiations between the Associated
Apothecaries and the Society of Apothecaries resulted in the pro¬
duction of a Bill by the latter body, which again excited the
opposition of chemists and druggists and is referred to in the
following entry in Allen’s diary : —
6th March, 1816. — “ Went with J. Barry to Freemasons’ Tavern to attend a
general meeting of chemistB and druggists on the Apothe¬
caries’ Bill— agreed to petition against it.
In the protracted negotiations which led to the removal of objec¬
tionable provisions from that Bill — eventually passed as the Apothe¬
caries Act, 18\5 — William Allen took an active part, continuing to act
as a member of the Committee and as trustee of the funds originally
subscribed in 1813 by chemists and druggists for opposing the Bill
of the Associated Apothecaries.
By the compromise then effected chemists and druggists main¬
tained their claim to the making up of physicians’ prescriptions
and generally to carry on the practice of pharmacy, while the pro¬
vision that no person should “ practise as an apothecary ” without
the qualification required by the Act, gave to apothecaries the
recognition, as medical practitioners, which they had long desired.
In both respects the passing of this Act had a beneficial effect,
though the precise interpretation of “ practising as an apothecary ”
has been matter of dispute and cannot be distinctly ascertained,
even from the language or general tenour of the Act.
The next occasion on which William Allen took a prominent part
in proceedings for the protection of chemists and druggists was in
connection with the Medical Bill introduced into Parliament in
1841, with objects somewhat similar to those of former Bills, and in
reference to it there is the following entry in Allen’s diary : —
12th February. — “ Hawes’s Bill about Chemists and Druggists is trying
to us. I have been requested to take the chair at a public
meeting of the trade on the second day, but am not up to it."
At the time Allen was suffering from an attack of influenza, but he
became a member of a committee appointed at the meeting held on
February 15, 1841, at the “ Crown Anchor ” to watch and oppose the
Bill in the interests of chemists and druggists. After the idea of
forming a society of chemists and druggists had been conceived at
the historic tea-party at the house of Jacob Bell, another public
meeting was held on April 15, 1841, to give effect to that idea and
the proposition that an association should be formed under the
title of the Pharmaceutical Society of Great Britain for the purpose
of increasing the respectability of chemists and druggists and pro¬
tecting their permanent interests, was moved by William Allen and
seconded by John Bell.
15th April. — “ Trade meeting at the Crown and Anchor, Strand. The
Pharmaceutical Society of Chemists and Druggists was
unanimously formed. ”
As one of the forty members of committee who were
then requested to frame laws and regulations for the government of
the Society, William Allen took part in drafting the laws of the
Society and, at a public meeting held on June 1, his motion for
passing the laws was seconded by John Bell. Two other partners in
the Plough Court firm — J. T. Barry and Daniel Bell Hanbury — were
also among the forty members of Committee who were then con-
stituted the first Council of the Society and, by general con¬
sent, William Allen was solicited, in recognition of the distinguished
position he occupied, to become the first President of the Society.
This circumstance is recorded in the diary as follows
1st June. — “The Pharmaceutical Society organised. I am appointed
President of the Council.”
The state of Allen’s health did not generally admit of his taking
the chair at the evening meetings of the Society which had been
commenced in May and were continued during the year. He
appears, however, to have attended the Council meetings and to
have taken an active part in the business of organisation.
15th July. — “ Attended the Council of the Pharmaceutical Society ;
passed the bye laws unanimously ; a very satisfactory
meeting. Our Vice-President, C. J. Payne, is a very
clear-headed, sensible man. Jacob Bell is indefatigable,
and one of our most useful members.”
In making arrangements for conducting examinations the Council
March 20, 1897]
PHARMACEUTICAL JOURNAL.
251
sought assistance from the College of Physicians and, in reference
to this, there is the following entry in Allen’s diary : —
17th November. — “ Received » letter requesting me to come to town to
join a deputation of the Pharmaceutical Society to the
College of Physicians to-morrow— an unpleasan inter¬
ruption, but must go."
He was then at Gravely Cottage, Lindfield, where he had latterly
spent much of his time.
Towards the end of the year, when proceedings relating to
medical reform required the Council to communicate with the
Secretary of State, a deputation was sent to the Home Office, and
the following entry in Allen’s diary is the last one in which the
Society is mentioned : —
1st Jany., 1812. — “ Interview with Sir James Graham on the subject of
the Pharmaceutical Society, together with C. J. Payne
and Jacob Bell. He received us very cordially. I in¬
formed him of the origin, nature, and extent of the
Society, and my friends also gave satis 'actory explana¬
tions. He promised that nothing should be done
bearing upon our trade without communicating with
me, which we acknowledged as very kind.”
In the same month he sent an address, which was read at the
evening meeting, pointing out the great importance of the Society’s
educational work and the especial necessity of “a competent
knowledge of chemistry ” as the foundation of a chemist and
druggist’s qualification.
At the first annual meeting of the Society, held at the “ Crown
and Anchor” in May, 1842, William Allen presided and congratulated
the members on having established a Society to provide for
their own protection and the benefit of the public, by promoting
education and obtaining the strength that results from union.
At the evening meeting of the Society in August the chair was
taken by the President and a prize was awarded to Robert
Bentley as the successful competitor at the conclusion of Dr.
Thomson’s lectures on botany.
The last occasion on which William Allen took part in the
proceedings of the Society was the second annual meeting, in
May, 1843, when he occupied the chair. After that time increasing
infirmity prevented him from attending to public business, and on
the 30th of December, 1843, at the age of 73, William Allen’s
earthly life closed peacefully at Gravely Cottage, Lindfield.
The further history of the Plough Court Pharmacy may be very
briefly summarised.
After the death of William Allen the firm was for several years
represented in the Council of the Pharmaceutical Society by Daniel
Bell Hanbury, who was afterwards appointed Treasurer, and con¬
tinued to hold that office until 1867. In the year 1868 he retired
from the business, and died in 1882 at the advanced age of 88.
J. T. Barry retired from the business in 1856, and since that time
the style of the firm has been Allen and Hanbury. Barry
died in 1864. Daniel Hanbury, the eldest son of D. B. Hanbury,
entered the business as a pupil at the age of sixteen, eventually
becoming a partner. He was a student in the laboratory of the
Pharmaceutical Society during the first session of 1844-45,
and soon afterwards commenced to contribute papers to the Phar-
vnaceutical Journal on the subject of pharmacology, which were
followed in 1874 by the publication of ‘ Pharmacographia,’ in con¬
junction with Ihe late Professor Fliickiger. In 1855 he was elected
a Fellow of the Linnean Society, and in 1873 of the Royal Society
— the fourth pupil in the Plough Court Pharmacy that had acquired
this distinction. His work in connection with his favourite sub¬
ject is too well known to require further mention here, and his
early death in 1875 at the ege of 49 was a very great loss to phar¬
macy as well as to science.
PHARMACEUTICAL SOCIETY.
EVENING MEETING IN EDINBURGH.
The second evening meeting in Edinburgh of the present session
was held in the Society’s Hall, 36, York Place, on Friday, March
12, at 9 o’clock, Mr. J. Laidlaw Ewing in the chair. The first
paper read was by Mr. W. S. Glass, on
Commercial Gingers and Essence of Ginger.
It is printed at page 245, and after reading it the author ex¬
hibited a percolator, costing a few pence, made of a cylindrical
zinc tube, 7 inches long and 3 inches in diameter, and closed
at one end with a concave zinc plate having perforations in
the central portion. Broken glass to the depth of about an inch
is placed in the bottom of the percolator and the ginger, in fine
powder, packed in layers above it. With such an apparatus a
pint of essence can be prepared in a reasonable time with very
small loss of spirit. When the ginger is exhausted the residual
spirit is driven out with water and reserved for future use.
Mr. J. B. Stephenson said he had for a long time taken a con¬
siderable interest in the making of essences, and the essence of
ginger was one of the most satisfactory examples of the process of
maceration. But he had never used any but the Jamaica ginger.
He imagined that he noticed a different flavour in the Cochin and
African.
In answer to Mr. Lunan, Mr. Glass said he did not separate the
essential oil from the oleo-resin.
Mr. Lunan referred to a similar paper which had been read
some years ago, the author of which used alcohol instead of ether,
and if he remembered right it made a better preparation. As to the
point which Mr. Glass had brought out that African ginger made
the most pungent essence, he had proved his point, but he doubted
if it would be so aromatic as Jamaica ginger.
Mr. Thomson asked if the percentage mentioned by Mr. Glass
had been obtained from the alcoholic or ethereal extract.
Mr. Glass said from the ethereal only.
Mr. Cowie asked if Mr. Glass considered the ether extract
superior to the alcohol. They would require to have some reason
for adopting ether instead of alcohol.
Mr. J. R. Hill said there was some force in what Mr. Stephen¬
son said that the paper was not by any means limited to discussing
essence of ginger. It was somewhat wider in its scope, and dealt
with three varieties of ginger. He thought Mr. Glass pretty well
confirmed the work of previous experimenters in proving the large
percentage of oleo-resin obtained from the African. It was alleged
that it had a harsh flavour as compared with J amaica. In these
essences Mr. Glass had shown them that the difference was not
important — at least not so very pronounced as to make so great a
difference in the practical use of these essences for flavouring
purposes. He had always had the impression that the Pharmaco¬
poeia only recognised Jamaica ginger, but that only proved his
ignorance. On looking up he found the Pharmacopoeia itself
stated no limit as to where the plant came from. Squire, in
his book, limited it to the West Indies and India.
As the ginger used was got from the West Indies and India, it
seemed reasonable to extend the field a little and take in African
and Cochin ginger, as well as being available for use. The
Jamaica ginger was very extensively used, and first-class
pharmacies excluded African and Cochin. But he did not see there
was a sufficient reason for that. It was rather keeping to old
tradition than selecting the finest variety for pharmaceutical
purposes. If cultivators saw that the produce of other districts
was being used it might result in their sending into the market a
better article. Mr. Glass’s percolator was a cheap piece of pharma¬
ceutical apparatus. Many used a glass percolator, but it had the
disadvantage of being very fragile, and not so easily replaced as
this practically indestructible percolator. It would not do to use
a zinc percolator in all circumstances, because the metal might be
acted upon and dissolve, but in the case of ginger there was no
danger of the zinc being dissolved.
Mr. Glass, in reply, said he had been asked if ether was
superior to any other solvent in extracting constituents. He did
not know if it was superior. He had the authority of Thresh and
Riegel also for saying that ginger yielded all its active constituents
to ether, alcohol, or chloroform. He took that for granted. He
thought it would be found that ether really extracted all the con¬
stituents.
252
PHARMACEUTICAL JOURNAL.
[March 20, 1897
Mr. I. W. Thomson then read a —
Note on a Sample of Scammony,
which is printed at page 245.
Mr. Rutherford Hill said he had had an opportunity of examin¬
ing the sample, and his results confirmed those just stated by Mr.
Thomson. The ether extract was decidedly oily, and seemed to
contain a small quantity of a fixed oil. When dissolved in caustic
potash solution it was reprecipitated on the addition of hydro¬
chloric acid, and this fact seemed to indicate that what¬
ever. the resin was, it was not scammonin. The alcoholic
extract consisted of brown-coloured extractive matter
which was not at all resinous. The portion soluble
in water he at first thought might be gum tragacanth,
but though some tragacanth might be present, it was
evident from the action of alcohol on the mucilage that it consisted
chiefly, if not entirely, of gum arabic. The insoluble portion
consisted almost exclusively of starch granules, which seemed to be
wheaten starch. There was a very small proportion of cellular
tissue which seemed to consist of portions of some root or stem,
and there \Yas a little dark earthy matter. A portion of the sample
was dried and with difficulty reduced to powder, when it bore a
passable resemblance to powdered scammony. It had also a
faint though quite recognisable aromatic adour, which had
a rather suggestive resemblance to that of genuine scammony.
The adulteration of scammony was a thing of very frequent
occurrence, and the peasants seemed to practise it systematically
before bringing their produce to market. It had often happened
that samples containing starch had been met with, and some of
them had contained as much as 50 per cent. But in all the
instances he had seen reported the samples contained a consider¬
able quantity of resin, and this sample seemed to differ from all
others in the fact that it contained practically none.
Mr. Cowie said that the experiments he had made on two
specimens corresponded with those made by Mr. Hill, except that
he found copper in the colouring of one, and there was a distinct
percentage of iron in the other. One contained a large amount of
wheaten starch. The consistency of the scammony appeared to
indicate tragacanth ; it was so hard and difficult to powder. The
other specimen contained no copper but lead. The percentages
soluble in ether were, he thought, 1 '933 in one, and the other 2 per
cent. The ash in the first was 1 '62, and in the other 2T4. Rice
starch was used to adulterate scammony. The ether soluble
extract was extremely oily, and the decoction gave a very strong
smell of scammony, much more so than one would expect from the
amount extracted.
Mr. J. R. Hill said that on examining the ash of the specimen
he had, he did come across what he considered a rather doubtful
evidence of lead, and that rather confirmed what Mr. Cowie had
said.
Recent Donations.
The Assistant-Secretary then directed attention to the books
recently added to the Library and to the donations to the Museum.
The latter included a specimen of Persian fennel fruit sent by Mr.
J. C. Umney, and a specimen of false packed Lima sarsaparilla
sent by Messrs. Hodgkinson, Treacher and Clark, per Mr. J. S.
Ward. The specimen contained two large pieces of stone. — On
the- motion of the Chairman, votes of thanks were awarded to the
authors of papers and the donors of books and specimens.
LEGAL INTELLIGENCE.
PROCEEDINGS UNDER THE PHARMACY ACTS.
Prosecutions at Airdrie.
At the Sheriff Court House, Airdrie, on Monday, March 15, a
number of cases of prosecution instituted by the Registrar under
the Pharmacy Acts, 1852 and 1868, Mr. Bremridge, came before
Sheriff Muir. Mr. Watt, Solicitor, Airdrie, instructed by
Mr. P. Morison, S.S.C., Edinburgh, appeared for the prosecutor.
The first case was against Hugh Barclay, assistant in the shop
of Dr. H. C. Reid, 50, Bank Street, Coatbridge, who was charged
with selling laudanum on November 4, and Powell’s balsam
of aniseed on November 21 last, to an agent of the Registrar.
The defendant pleaded guilty, and sentence was reserved.
The next case was against Thomas Whiteford, assistant in the
shop of Dr. Munro, 90, Main Street, Coatbridge, who was charged
with selling laudanum on November 4, and prussic acid, chloro¬
form, and morphine on November 21 last to an agent of the
Registrar.
Defendant pleaded guilty, and sentence was reserved.
The next case was against Peter Fenton, assistant in the shop
of Dr. White, 13, Bank Street, Coatbridge, who was charged with
selling laudanum on November 4 to an agent of the Registrar.
Mr. Wm. Orr, solicitor, Coatbridge, appeared for defendant,
who pleaded guilty, and sentence was reserved.
The next case was against David Ogilvie, assistant in the shop
of Dr. Murray, 128, Bank Street, Coatbridge, who was charged
with selling Budden’s Balsam of Horehound, on November 21 last, to
an agent of the Registrar.
Mr. J. H. Russell, solicitor, Coatbridge, appeared for defendant,
who pleaded guilty, and sentence was reserved.
The next case was against David Mcllwraith, assistant in the
shop of Dr. Martin Thomson, 141, Graham Street, Airdrie, who
was charged with selling laudanum, on November 4, and bella¬
donna and Bow’s liniment, on November 21 last, to an agent of
the Registrar.
Defendant pleaded guilty.
Mr. Watt said he had to ask for a conviction and penalty in each
case. It had been freely admitted that these proceedings were
taken in the public interest.
The Sheriff : Where has that been admitted ?
Mr. Watt : It is stated in the preamble to the Act of 1868 that it
is expedient for the safety of the public.
The Sheriff : Oh, yes ; but I want you to show me where it has
been admitted by the judges ?
Mr. Watt : It is stated by the Lord Justice Clerk in the Tomlin¬
son case, and the same general view runs through the whole of the
judgments in the English cases. The Society has no desire to sue
for merely vindictive penalties, but I must ask for such a penalty
as will put a stop to the practices here complained of. In a
similar case in the Hamilton Sheriff Court the other day a penalty
of £3 with £2 14s. 4 d. of expenses was imposed.
Mr. Orr said it was said that the prosecution was not vindictive,
but it was very strange that though this Act had been in force for
thirty years, and doctors’ shops had been conducted in Coatbridge
all that time just as they are now, no person had ever before been
proceeded against in Coatbridge. He did not think the Pharmacy
Act was ever intended to cover such acts as those charged in these
complaints. But the defendants were only assistants, and had no
means to conduct an expensive defence, and therefore they had
pleaded guilty. He had also to complain that this Society had no
justification for hanging up these charges since the month of
November.
Mr. Watt said the delay was necessary, and could easily be
explained.
Mr. Orr said the defendants should have been told at the time
or very shortly thereafter of the offence, so that they might get up
evidence to rebut the charges made by these professional
witnesses. It might have been proved that the doctor was
resent when the poisons were sold. He might have been in the
ack shop. These professional witnesses were paid by the Society
to scour the country and secure convictions against such persons
as the defendants. He had also to complain that the articles sold
here, such as Powell’s balsam, were sent out to the doctors by the
makers without any label upon them to indicate that they con¬
tained a poison.
Mr. Russell said he concurred in the remarks made by Mr. Orr,
and further, he questioned whether these prosecutions were really
in the public interest. It was strange that they were all against
doctors’ assistants, and he made bold to say that the law was far
more frequently broken by unqualified assistants in the shops of
pharmaceutical chemists than in doctors’ shops.
Mr. Watt said the parties here had pleaded guilty, and he did
not admit the statements made on the other side, which would
have been disproved if the evidence he possessed had been called
for. There had been prosecutions in Airdrie of a similar kind to
those before the date of these offences. As to the statement about
Powell’s balsam, he showed the Sheriff the bottle sold in this case.
March 20, 1897]
PHARMACEUTICAL JOURNAL.
253
which bore a label on the outside wrapper stating that it contained
morphine, and was therefore labelled “Poison.”
Mr. Orr : The one I have here is not labelled “Poison.” It is
Budden’s balsam.
Mr. Watt : You mentioned Powell’s balsam. There have been
several prosecutions for the sale of Budden’s balsam in the
Greenock Sheriff Court, which were fully reported in the local
newspapers. The inner label bears the word “Poison,” and it is
well known to contain poison.
The Sheriff said that in giving judgment in cases of this kind
he was not perhaps entitled to express an opinion as to
the policy of the Pharmacy Acts. But he would have had no
hesitation in doing so were it not that sitting here as Sheriff
it might be considered presumptuous on his part if he said what
would be understood as condemning an Act of Parliament. He
was, however, perfectly warranted in saying that were it not for
the decisions which had been given under these statutes in the
Courts of England and Scotland, he would have had very great
difficulty indeed in finding that the parties charged before him to¬
day came within these Acts at all. Looking to the 15th Section of
the 1868 Act, he could easily see the possibility of holding
that it did not apply to assistants at all, but was
directed solely against unqualified owners of shops. He
must express his great surprise that in all these cases the
parties who own the shops are duly qualified medical practitioners,
and he did not think it wras ever intended by the Act that their
assistants should be selected and brought here for punishment. As
he had already said, he had very great difficulty in holding that
they came within the Act. He was struck by the remark made by
Mr. Orr that this Act was passed in 1868, and that for thirty years
this practice of having unqualified assistants in doctors’ shops had
been allowed to go on in Coatbridge without question till now.
It was said by the prosecutor that these proceedings were taken
in the public interest. On the contrary he had a very strong
suspicion that behind all this, some private interest of which they
knew nothing was involved. It was still more remarkable that
Airdrie and Coatbridge should have been chosen as the happy
hunting ground for all these cases. He would like to ask Mr. Hill
what had been done in such large cities as Glasgow, Edinburgh,
and Dundee.
Mr. Watt said he was informed by Mr. Hill that there had been
several cases in each of these towns during recent years.
The Sheriff : That may be so, but I would like to ask Mr. Hill
if he has had any cases against the Glasgow Apothecaries’ Company
in Virginia Street, or the Apothecaries’ Company in Glassford
Street, in Glasgow. There must be a number of unqualified per¬
sons in these places who are breaking the law every day.
Mr. Watt : I am informed that in all cases where a complaint is
made to the Registrar proceedings are taken if evidence of an
offence is obtained, and chemists’ assistants have been prosecuted
in a number of instances. But the Registrar cannot take action
unless information is lodged.
The Sheriff : I do not see why these professional witnesses
should be sent into this district to trap these doctors’ assistants and
bring them here for punishment, and to mark my disapproval of
the action of the Pharmaceutical Society in this matter, and my
condemnation of the proceedings in these cases under the
Pharmacy Acts, I will inflict a nominal penalty of 2s. 6 d. on each of
the defendants, with 2s. 6 d. of expenses.
In the case against John E. Miller, assistant to Dr. Arthur,
1, High Street, Cross, Airdrie, which had been adjourned by the
Sheriff to May 7, on account of the illness of the defender, the
Registrar, taking into consideration the serious illness of the
defender, and the fact that he has ceased to act as assistant to
Dr. Arthur, has withdrawn the charge against him.
PROCEEDINGS UNDER THE FOOD AND DRUGS ACT.
What is Glycerin and Lime Juice?
At Brentford Police Court on Saturday last, before Mr. Montagu
Sharpe, chairman, Mr. J. Allen Brown, and other justices, William
Leighton, chemist and druggist, of Hanwell, Middlesex, was sum¬
moned at the instance of Walter Tyler, Inspector under the Food
and Drugs Act to the County of Middlesex, for having sold a
bottle of glycerin and lime juice not of the nature, substance, and
quality demanded.
Mr. W, A. Davis, solicitor, defended. The proceedings were
brought under the 6th Section of the F ood and Drugs Act, and
the facts showed that the sample was purchased in the ordinary
way. The defendant declined to have it divided, therefore, half
was sent to the public analyst, who certified as follows : “I am
of opinion it contains no glycerin. The sample has undergone no
change that will interfere with analysis.”
It was urged for the prosecution that the compound was a drug,
glycerin being mentioned in the British Pharmacopceia, and also
that very little so-called glycerin and lime juice contained glycerin.
Mr. Davis, for the defence, submitted that the compound con¬
tained glycerin. The certificate of the analyst should have set
out the actual parts and ingredients, which would have materially
helped the defence. His client prepared the compound himself,
and used ingredients which in themselves would create glycerin.
He had done all he could do, and if the drugs failed to do what
they should do, he could not be held liable.
Mr. Edward Bevan, the analyst who granted the certificate in
the case, called by the defence, stated, in reply to questions, that
he did not analyse the mixture with a view to finding out what it
actually contained. He only devoted his attention to tracing what
it did not contain. It contained olive oil and, he thought, alcolite
as well.
Mr. Davis : And is it not a chemical fact that when mineral oil
is mixed with alcolite it forms glycerin? — It depends entirely upon
the way in which you mix them and treat them.
Mr. Davis : Will not alcolite fetch glycerin out of mineral oil ? —
No, it would want treating with caustic soda.
Mr. Davis : It cannot be formed without it ? — No.
Mr. Davis : If saponification takes place it might be formed?— Yes.
Mr. Davis : Will you say whether it did or did not take place ?
—No.
The Chairman : As a fact, there may be the materials to produce
it, but it had not taken place ? — Yes, exactly.
The Chairman: Every chemist should see that it takes place, not
leave it to chance.
Mr. Davis replied in that event he would have to open the bottle
again and test it himself. That would be impossible.
The Chairman : I am not a chemist, but to my lay mind nothing
should be left to chance.
Mr. Allen Brown : Under the most favourable circumstances
would olive oil and alcolite produce a sufficient quantity of glycerin
to satisfy you ? — No.
Mr. Davis : Have you examined many samples with the same
result ? — Yes ; and I have found none contain glycerin.
Inspector Tyler : Are you sure you heard the question rightly ?
You say you never found glycerin in this compound ?
Mr. Bevan : With the exception of one sample, in which there
might have been a little glycerin.
The Chairman : Why not put glycerin in it ?
Mr. Davis : I am not a chemist. I can’t tell you.
The Chairman : There must be a conviction. It is the first case
of its kind, and we hope manufacturers will be more careful. The
fine will be 20s. and costs.
At Sunbury Petty Sessions on Monday, before Mr. J. Ashby,
chairman, and other justices,' Thos. Mann, chemist and druggist,
of Park Terrace, Hampton Hill, Hampton, Middlesex, was simi¬
larly summoned.
The evidence disclosed that Wm. Churchman, assistant to
Inspector Tyler, purchased from the defendant a bottle which bore
a label as follows : “Lime Juice and Glycerin. Apply with sponge
or brush. Effectually cleanses the skin and hair. It allays irrita¬
tion and produces a fine silky and brilliant texture for the hair.
Shake the bottle before using.” A portion was sent to the analyst,
whose certificate was as in the foregoing case.
Inspector Tyler, in cross-examination by the defendant, admitted
that the bottle did not appear to have been opened when pur¬
chased.
The defence was that the defendant had sold the compound
exactly as it was received from the wholesale makers, “F. New-
bery and Sons, London,” and the defendant put in a declaration
by a gentleman at Manchester, stating the compound contained
glycerin.
The Bench declined to receive the document unless the writer
was to be called.
The defendant thereupon elected to have the remainder of the
sample sent to Somerset House for analysis, and the case was
adjourned.
254
PHARMACEUTICAL JOURNAL.
[March 20, 1897
THE STUDENTS’ PAGE.
NOTES ON THE PHARMACOPOEIA.
Butyl-Chloral Hydras. — The constitutional formula for this is
OTT
CHj'CHCPCCVCH-^qjj The reactions which occur in making
it are complicated: the main feature may, however, be remem¬
bered, namely, that it is a polymerisation product. Aldehydes as
a class are very prone to form such — for instance, two molecules of
acetic aldehyde polymerise to form aldol (an aldehyde-alcohol) —
CHsO -0 -H + CH3C -0 -H = CH3CH( OH) -CH2 -C '0 H.
Aldol.
This polymerisation has changed one aldehyde grouping into an
alcoholic one — hence the name ald-ol. Aldol easily loses water, and
is converted into crotonic aldehyde —
CH3-CH(0H)-CH2-C0H-H20 = CH;j-CH:CH-C-0-H.
Aldol. Crotonic aldehyde.
Crotonic aldehyde, as may be seen by inspecting its formula, is
derived from butylene, a member of the ethylene (unsaturated)
series. Butyl-chloral was formerly (and erroneously) supposed to
be a tri-chloro-derivative of crotonic aldehyde, and was called in
consequence croton-chloral hydrate. Crotonic aldehyde forms a
chloro -derivative by the action of chlorine,
CH3-CH:CH-C0H + C12 = CH3'CH:CC1C0H + HC1,
and this chlorcroton aldehyde, being an unsaturated compound,
takes up two atoms of chlorine to form butyl-chloral. We started
with aldehyde containing two carbon atoms in the molecule, but
obtain a butane derivative containing four, owing to the poly¬
merisation previously mentioned. The test with solution of potash
is intended to distinguish it from chloral, which yields chloroform
and formic acid, the acid reacting with the alkali to form alka¬
line formate,
CC13
H
C-O-H-
. OH
Butyl-chloral, however, yields allylene dichloride and formic
acid when acted upon by caustic potash. It first forms a tri-chloro
derivative of propane (C3H8), just as chloral yields a tri-chloro
derivative of methane.
CHo-CHCl-CCL
H
C-O-H
OH
but the tri-chloro propane
Chloroform is not further acted upon,
loses an atom each of chlorine and hydrogen by the action of
potash, and allylene dichloride results : —
CHs-CHCl-CHCla = CHs-CCl : CHC1 + HC1,
Allylene dichloride.
Allylene dichloride has an aromatic odour which somewhat
resembles that of chloroform. It is, however, easily distinguished
by the iso-nitrile reaction (see Chloral Hydras).
Calcii Hypophosphis. — The anhydride corresponding to hypo-
phosphorous acid, which would have the formula P20, has not been
obtained in the free state. Compare this acid with those derived
from the two higher oxides, P403 and P205.
P20(?) + 3H20 = ' 2H3P02.
P203 + 3Ho0 = 2H3P03.
P2Og + 3H20 = 2H3P04.
Although according to these formulae each acid contains three
atoms of hydrogen, the first is monobasic, the second dibasic, and
the third tribasic, i. e. , one, two, and three atoms of hydrogen
respectively are replaceable by metals to form salts. For this
reason the formulas for the first two are often written H2PH03 and
HPH202 to indicate this difference in behaviour of the hydrogen
atoms. An explanation is furnished by the usually accepted
constitutional formulae for these acids.
/OH .OH .OH
OPC-H OPC-OH OPcOH
XH \H NOH
Hypophosphorous Acid. Phosphorous Acid. Phosphoric Acid,
in which it is seen that the number of hydroxyl (OH) hydrogen
atoms corresponds to the number of atoms replaceable. These
formulae also help to explain the behaviour of the three
acids to nascent hydrogen— the first two yield PH3, but phos¬
phoric acid does not. The formation of PH3 is probably determined
by the direct connection of hydrogen to phosphorus, the three
atoms of hydrogen in phosphoric acid being connected with oxygen.
Compare the behaviour of sulphurous acid 02S and
OTT
sulphuric acid 0.2S <Cqjj towards nascent hydrogen.
The formation of calcium hypophosphite by the P. B. method is
attended by the evolution of PH.?. The PH3 is never pure, as
several secondary reactions take place, which will be discussed
under “ Sodii Hypophosphis.” The equation usually given for
this reaction —
2P4 + 6H20 + 3Ca2(HO) = 3Ca2(PH202) + 2PH3
is simplified by the hypothetical interpretation that phosphorus
is oxidised to P20, PH3 being formed in equivalent quantity by
reaction with water —
: h2
0 r
: 2P H2
0 6P =
h2
0
The 3P20 unites with water to hypophosphorous acid, P20 + 3H20 =
2H3P02 and this is neutralised by the calcium hydrate with forma¬
tion of calcium hypophosphite.
The ash left by ignition is chiefly pyrophosphate and meta¬
phosphate of calcium, a part of the hypophosphite being oxidised
to phosphate at the expense of another part, the phosphorus of
which is consequently reduced to PH3. Insolubility in rectified
spirit distinguishes it from the sodium salt, which is soluble.
Hypophosphites and hypophosphorous acid are easily oxidised
into phosphates, hence they act as reducing agents. Mercuric
chloride is first reduced to mercurous chloride (white precipitate)
and then to metallic mercury (grey precipitate).
(i.) H3P02 + 2(OH2) + 4HgCl2 = H„P04 + 4HC1 + 4HgCl.
(ii.) H3P02 + 2(OH2) + 4HgCl = H3P04 + 4HC1 + 4Hg.
As in many other similar reactions, water plays an essential part
in the reactions. Lead acetate produces a precipitate in the solu¬
tion if any phosphate be present (phosphate of calcium is produced
by some of the secondary reactions referred to in the manufacture
of the hypophosphite). The reaction with permanganate of
potassium, which is employed as a quantitative test for purity,
results in the formation of phosphate by oxidation, the perman¬
ganate being reduced to hydrated manganese oxide.
THE FLOWERS OF MARCH.
Two or three natural orders can be conveniently studied during
this month. The Cruciferae are represented by two garden plants,
Arabis alpina and Cheiranthus cheiri, and by the wild plants
Cochlearia danica, Draba verna, Capsella Bursa pastoris, and the
rarer species Hutchinsia petroea and Teesdalia nudicaulis. When
collected for examination, specimens with well-developed fruit
should be selected, so as to obtain some idea of the characters of
the sub-orders Siliquosce, Siliquosce latiseptce, and Siliculosce angusti-
septce. The Arabis and wallflower belong to the first, having a narrow
elongated fruit with two nearly flat valves. Cochlearia and Draba
belong to the second, which is characterised by the fruits consist¬
ing of two convex valves, with a replum or membrane of their own
width between them. Capsella belongs to the third, in which the
valves are bent or folded, so that the replum is narrower than the
valves and forms a visible line in the centre of the fruit. The sub¬
divisions of this large order depend upon the way in which the
radicle is folded in the seed, the principal variations being when it
is folded along the edge of the cotyledons (accumbent), upon the
back of one cotyledon (incumbent), or lies between the folded
cotyledons (conduplicate). These may easily be seen by soaking seeds
of wallflower, Virginian stock, and white mustard in tepid water, and
placing them on wet flannel in a saucer in a warm place. As- the
testa or seed-coat bursts, the position of the radicle becomes
evident ; or a section may be cut through the seeds with a sharp
penknife or razor.
The gentian family is represented by Gentiana acaulis, a
favourite garden flower. The opposite entire, hairless leaves, the
twisted aestivation, one-celled ovary with parietal placentation and
marcescent corolla should be noted as characters of the order. The
Thymelaeaceae are exemplified in Daphne laureola and D. mezereum.
The coloured perianth, imbricate aestivation, one-celled ovary with
pendulous ovule, and the remarkably tough, finely-fibrous bark
should be observed as characteristic features of the order. In
D. mezereum the leaves are deciduous and the flower purple, in
D. laureola the leaves are evergreen and the flowers greenish-
yellow. The Lauraceae and Elaeagnaceae are nearly allied to this
family, but the former have usually valvate anthers and the
perianth in two rows, the latter have an erect ovule and leaves
usually covered with elegant scales.
March 20, 1897]
PHARMACEUTICAL JOURNAL.
2b 5
Pharmaceutical Journal.
LONDON : SATURDAY, MARCH 20, 1897.
THE SOCIETY’S JOURNAL.
On various occasions remarks have been made at the
annual meetings, in reference to the financial relations of
the Journal, which have been indicative of misconception as
to the conditions under which the Journal is produced, and
though the explanations offered on those occasions have
shown that there is not any ground for the supposition that
the Journal is a drain upon the Society’s funds, there is still
need for some further elucidation of the matter.
At the second anniversary meeting of the Society after the
passing of the Pharmacy Act, when the project of a weekly
publication was under consideration, the late John Mackay —
who always took a deep interest in the success of the Pharma¬
ceutical Journal as being one of the most important features of
the Society’s work — prepared a comprehensive statement of its
financial history. He then showed that, during the twenty-
eight years of its existence as a monthly publication, the
average cost of the Journal to the Society had amounted to
£604 a year, inclusive of postage, and that the number of
persons to whom it was supplied being on the average 2462,
the cost of the Journal to each subscriber had been at the
rate of about five shillings a year. This fact was put forward
in support of the change then contemplated and in answer
to the extreme views that were held on the subject by some.
For the first eleven years after weekly publication commenced
the details of expenditure and of revenue from advertisements
and sales were not published in the annual financial statement,
but only the balance of the one amount over the other. The
data given were, however, sufficient for the purposfe of show¬
ing the actual cost of the Journal to the Society and, during
those eleven years, it amounted on the average to <£765 a
year, inclusive of postage. The number of subscribers to the
Society of all classes was, on the average, 4700, so that the
cost of the Journal to each subscriber was at the rate of
3s. id, a year, inclusive of the large number of copies supplied
gratuitously to honorary members, societies and others.
Prom the year 1881 it was the practice to publish full
details of the expenditure, etc., and during the fifteen years
up to the end of 1895 the cost of the Journal amounted on
the average to about £1200 a year. This increased cost
was partly due to the larger number of subscribers to the
Society, increased circulation, enlargement of the Journal,
publication of supplementary matter and various other cir¬
cumstances ; but, including postage, it did not, on the average,
amount to more than 4s. id. a year for each subscriber to the
Society, taking the number of members, associates, and
students during the fifteen years to have been on the average
5600.
The publication of details of expenditure and of revenue
from advertisements and sales, during this latter period, shows
that, including the cost of postage, the outlay on the Journal
has amounted on the average to £5655 a year, so that the ex¬
penditure in its production has been at the rate of more than
20s. a year for each subscriber to the Society. It may have
been that some misapprehension has been created by the
magnitude of that expenditure, though in point of fact it
has been, for the most part, covered by the annual revenue
from advertisements and sales, so that, taking the whole
period of fifteen years, the Journal has been far from dis¬
advantageous ; for subscribers to the Society have had a
return amounting in some cases to nearly the whole of their
subscription, and in others to double as much.
Within the last few years the changes made in connec¬
tion with the Journal, in pursuance of the suggestions
of Mr. R. A. Robinson as well as many other members of
the Society, have entailed an expenditure greater than that
shown for the average of the last fifteen years ; but it has been
in compliance with a very general demand on the part of the
subscribers to the Society and the result has met with such
very general appreciation and approval as to furnish great
satisfaction and encouragement. Other advantages have
also been secured by the recent changes, but this is not the
place to enter into a consideration of them. The object
now in view, in referring to the Journal, is to show that the
actual cost of its production has amounted to only a
small fraction of each subscriber’s annual contribution, for
which the Journal has been no inconsiderable return. The ex¬
planation given is intended for the information of those who
are co-partners in this concern ; the data on which it is based
are taken from the audited financial statements published
each year, and they can be easily verified by any one. If
the prosperity of the Pharmaceutical Journal be viewed in
any quarter with jaundiced eyes, perhaps even by some
members of the Society, the facts above mentioned ought at
least to be sufficient to refute the suggestions of interested
detraction. — Quare fremuerunt gentes l
THE PROPOSED NEW BYE-LAWS.
The discussion of the proposed new bye-laws at the
meeting of the London Chemists Association, reported at
page 259, furnishes a most gratifying illustration of the good
effects resulting from union and association among members
of the pharmaceutical body. Never has there been such un¬
qualified expression of gratitude to the Council as fell from the
speakers on that occasion. Each and all of them fully appre¬
ciated the beneficial influence of its endeavours to promote
the best interests of chemists and druggists, and to make
them a body deserving the respect of the medical profession
and the public generally. There was — by permission of the
President— a contrary and somewhat exotic statement of
circumstances supposed to have an opposite tendency ; but
though patiently listened to, it met with most emphatic dis¬
approval and condemnation.
The report of the meeting should be an excellent object
lesson to individuals who think to further their private
interests by sowing dissension in the ranks of the members and
associates of the Pharmaceutical Society. If there be one
feature more marked than another in persons connected with
the Society, it is the almost absolute unanimity with which
they loyally support their elected representatives in all cases
of grave emergency and constitutional importance. A few
members here and there, whose business interests seem inevit¬
ably hostile to those of the body which claims their
allegiance, may feel impelled at times to protest against
movements tending to benefit the Society as a whole ;
but common decency should at least prevent them from
descending into the arena and openly flaunting their desire
that private interests should prevail over public policy.
256
PH ARM ACE UTIC AL JOURNAL.
[March 20, 1897
ANNOTATIONS.
The Proposed New Bye-Laws have attracted a certain measure
of attention, and the comments made thereon reveal the usual
amount of misconception as to what is possible and what
it is desired to effect at the present time. It was ex¬
plained last week that the powers possessed by the Pharmaceu¬
tical Society do not permit the Council to call upon each
registered person to pay an annual registration fee. For the same
reason it is not at present possible to admit chemists and druggists
generally to full membership of the Society, nor is it possible or
desirable to compel associateship in the case of all who pass the
qualifying examination. Such changes as these would require an
amending Act of Parliament, and not a mere alteration of Bye-
Laws, and the present is not a favourable moment to introduce
Bills into the legislative chambers. The idea that a separate
charge can be made for examination and registration respectively
is also impracticable. Although it is customary to speak of the
Minor Examination fee, the fact must not be lost sight of that
it is in reality a registration fee, according to the terms of the
existing Bye-Laws, passing the examination being there regarded
as simply one condition of registration.
The Registration Fee imposed by the Act of 1852 has no
bearing upon the present case. It related to a purely voluntary
qualification, whereas registration under the Act of 1868 relates to
a qualification that is compulsory for all who clesire to practise as
chemists and druggists. Section VII. of; that Act left the fees pay¬
able for examination and registration to be fixed and determined
by Bye-Law, and as it now stands, Bye-Law 16 stipulates
that “all persons desiring registration as . chemists and
druggists under the Act, 1868, ..... shall pay a fee .
and pass the Minor examination, whereupon they shall be registered
accordingly.” Nothing is said about examination fees, properly
so-called, until we come to Bye-Law 23, which specifies the amounts
payable in the case of unsuccessful candidates attending on
subsequent occasions. Hence it is clearly manifest that the Pharma¬
ceutical Council in drafting the existing Bye-Laws, and the Privy
Council in sanctioning them, regarded the initial payment as being
primarily in the nature of a registration fee.
Registration as a Chemist and Druggist was first under¬
estimated at three guineas, apparently in forgetfulness of what
perpetual registration might involve, or in the hope that most
registered chemists would become members of the Society.
It has proved too little, and now it is proposed to make
the fee fairly cover all incidental expenses by raising it to ten
guineas. It will still remain the lowest fee charged for pro¬
fessional registration in this country, and should be approved by
all men on the Register as offering a means of relieving the
pressure in their ranks. The fact that the registration fee is
payable before qualification should have a healthy influence in
restraining those who are not properly educated from presenting
themselves for examination. Even in cases of failure no
hardship will be inflicted, as the same supplementary fee as at
present will be payable on the next occasion. Of course, if
anyone should be so foolhardy as to present himself for ex¬
amination before he could reasonably expect to pass, he must
be prepared to pay the penalty of a second registration fee.
In such cases, however, sympathy would be distinctly out of
place.
The Advantages Derived by future chemists and druggists,
by virtue of having paid the increased registration fee, will
remain as at present, but much enhanced in degree. Thus, in
addition to securing permanent registration, with all the
advantages accruing therefrom, every chemist and druggist will
benefit from the extra power conferred upon the Pharmaceutical
Society by a permanent increase in its income, to administer the
protective sections of the Pharmacy Acts, and to extend the sphere
of its Benevolent Fund. Up to the present those outside the
Society have reaped a proportionally much larger share of all these
benefits than those who regularly contribute to its funds, and
there is perhaps little reason to believe that this disparity will
be remedied in the immediate future. Both in defence and attack
the members and associates of the Society are left to bear the
brunt of the fray, and it is but reasonable, therefore, that a little
of the financial burden should be shifted on to the more numerous
shoulders of those who might otherwise be content, like so many
of their predecessors, to take all and give nothing.
The Proceedings in Scotland, reported last week and in the
present issue of the Journal, serve as a concrete instance of the
manner in which steps taken by the Society benefit the whole
craft, at no expense to any except the proportionately small
section who regularly contribute to the corporate funds. The
Glasgow cases were of the old familiar sort, the defendants being
unregistered persons in the employment of medical men with
so poor an idea of the dignity of their calling that they must
needs envy and intercept the small profits that should
rightfully accrue to local pharmacists. At Hamilton the
Sheriff was impelled to speak very forcibly concern¬
ing the danger to the public arising from the use of infinitesi¬
mal type on labels to indicate that proprietary preparations are
poisonous, and the consequent risk of such preparations being
regarded as innocuous mixtures. In Airdrie, on the other hand,
the utmost lack of sympathy with the Society’s efforts to protect
the public was manifested by the Sheriff, and the unfortunate
spectacle was presented of the dispenser of justice (sic) taking a
strongly partisan view of the proceedings of a public body which
was only endeavouring to carry out its statutory obligations. The
Evening Dispatch, a second-rate Edinburgh news-sheet, edited by
a pawky individual with a fine sense of the fitness of things,
expresses the opinion that if a Sheriff ventures to suggest that the
officials of the Society are conducting prosecutions for some
private interest, the public may conclude “that the Sheriff is abso¬
lutely incompetent for his post,” unless there is something deplor¬
ably wrong with the method of the prosecutions. Since it is well
known that there is nothing wrong with the method of the pro¬
secutions, except it be conducting them too openly and fairly, the
public will be compelled to fall back upon the alternative so
appropriately expressed by the Evening Dispatch, as that paper cer¬
tainly ought to be in a position to gauge the matter correctly,
whether it does so or not. But whatever may be thought on this
point, our Scottish friends owe it to themselves to put this matter
straight, and they should not hesitate to take such steps as will pre¬
vent the recurrence of these too frequent scandals in their cour ts.
The Benevolent Fund seems to be appreciated in Manchester
more than elsewhere, if we may judge from the great activity
there displayed in seeking to augment the amount of money at
present available for specially pharmaceutical charitable purposes.
The Committee organised by Mr. Kemp has promptly secured pro¬
mises of extra donations to the extent of more than seventy
pounds, and we now publish an intimation of the fact that the
March 20, 1897]
PHARMACEUTICAL JOURNAL
257
chemists’ assistants and apprentices in the Manchester district
are about to devote their energies to the same laudable purpose, ex¬
pressing their loyalty at the same time that they assist those of
their craft who have fallen out, or may yet fall out by the way.
The arrangements made at other centres are not yet, we under¬
stand, in a sufficiently advanced state to enable the organisers to
publish any results of their respective appeals.
A Food and Drugs Millennium, from a certain point of view,
ought to be the outcome of the action of the local authorities
responsible for the administration of the law, as illustrated at
Brentford Police Court. Inability to find arsenic in so-called
arsenical soap has been followed by failure to detect glycerin in
a preparation sold as “Glycerin and Lime Juice.” Presumably,
lime juice was found, though that circumstance is not clear
from the report of the case. But really, after earning un¬
dying fame by another failure — inability to find glycerin,
to wit, where it never professed to exist — it would have been super¬
fluous to stoop to report the discovery of the presence of lime j uice
which was equally absent. Regarding the wonderful perspicacity of
the magistrates we do not venture to speak. Readers will
doubtless be overcome with awe at the depth of their wisdom and
struck with the prettiness of their humour. It is clear, however,
that the High Court of Justice need not lack cases for appeal yet
awhile, and equally clear that olive oil emulsified with an alkali to
form a hair dressing must drop one at least of its familiar names in
Middlesex. Parenthetically, it may be remarked that the name
always was a foolish and peculiarly unsuitable one for the mixture.
But when did hair oil become a food or a drug, and what will the
Middlesex Dogberrys next bring within the scope of the Sale of
F ood and Drugs Act ?
The Warning about Saffron adulterated with barium sulphate,
which a correspondent published in our pages a fortnight ago
(ante, p. 223), has now been justified by facts. A tobacconist in
the Caledonian Road has been prosecuted by the Islington Vestry
for selling saffron containing the enormous proportion of thirty-six
per cent, of barium sulphate, and the defence raised was that it
had been sold in the condition in which it was bought from “ a
firm of wholesale chemists.” It would be interesting to know who
the “wholesale chemists” are. Moreover, it would be instructive
to learn why the plea that defendant was not a chemist but “a
tobacconist who also sold ‘patent medicines,’ ” should have entitled
him, on conviction, to consideration at the hands of the magistrate,
Mr. Bros, who simply ordered the payment of costs. Are chemists
alone to be singled out for the infliction of heavy fines when articles
that may be used for medicinal purposes are sold of inferior
quality ? Or, is it to be assumed that the public requires protec¬
tion against chemists, and not against other tradesmen who are
continually encroaching on the chemist’s legitimate domain ?
Justice should, at least, be dealt out with an even hand.
The Samples of Drugs examined during 1895, under the Sale
of Food and Drugs Act, numbered 1439, and according to the
twenty -fifth annual report of the Local Government Board, of that
number 158, or IDO per cent., were adulterated. The percentage
was practically the same as in 1894 (11 '2). The principal articles
condemned were 39 out of 123 samples of “nitre” (? spirit of
nitrous ether), and 33 out of 195 of “rhubarb” (? tincture of rhu¬
barb). “ Proceedings were taken in 69 cases, and 57 small fines
were inflicted, amounting in all to only £27 Is. 6 cl. Apart from
one fine of £5, the average of the fines was about 8s.” This
is all the information concerning adulterated drugs that
the Local Government Board vouchsafes to give, though
in addition to these scanty particulars it would be interesting
to know the class or classes of retailers from whom samples were
purchased, how many were chemists and druggists, and so forth.
But this would be quite opposed to precedent, and presumably,
therefore, out of order in a Government publication. Meanwhile
it is safe to say that the proportion of cases in which chemists were
fined was very infinitesimal indeed. The Medical Press apparently
jumps to the conclusion that the condemned samples were such as
might have been supplied by persons who dispense physicians’
prescriptions, but such a conclusion is quite unwarranted, grocers,
unqualified dealers in drugs, hucksters, and possibly medical men
who dispense their own prescriptions being responsible for nearly
all sales of adulterated drugs. Amongst the miscellaneous articles,
with which public analysts have been busy, is classed bees¬
wax, which was found deficient in 23 out of 52 cases, whilst cocoa
was adulterated in 56 out of 182, vinegar in 23 out of 375, pepper
in 8 out of 1599, lard in 26 out of 1663, and spirits in 702 out of 4241.
The Royal Institution programme contains the announcement
that, on Thursday next, March 25, Profossor W. Boyd Dawkins
F.R.S. will begin a course of three lectures at the Royal Institution
on “ The Relation of Geology to History.” The first lecture of
this exceptionally attractive series will deal with “ The Incoming
of Man,” the second with “ The Frontier of History in Britain,”
and the third with “ Roman Britain.” The Friday evening
discourse on March 26, will be delivered by Sir William Turner,
F.R.S. , his subject being “ Early Man in Scotland.”
‘ The Medical Register ’ for 1897 is a ponderous tome of nearly
sixteen hundred pages, and is accompanied by ‘ The Dentists’
Register,’ occupying two hundred and thirty pages more. From
the former we gather that there were 34,478 persons registered at
the end of December last, as against 33,601 at the end of the
previous year. The number added by registration during 1896
was 1385, less than any year since 1891, and the number restored
(52) was the lowest since 1878. The number of names removed
from the Register during 1896 was 560. The ‘ Dentists’ Register 5
for 1897 shows that 4860 persons were qualified to practise dentistry
at the close of the past year. Of these, 1519 were licentiates in
dentistry, and 24 foreign (American) dentists. Only 30 of the
remainder possess any surgical qualifications, the large number of
3287 being persons who have made a declaration to the effect that
they were bona-fide engaged in the practice of dentistry at the
passing of the Dentists’ Act.
The Post Office Test Case, respecting the right claimed by
the authorities to charge return postage on undelivered news¬
papers, came on atBowStreetPoliceCourt, on Wednesday, March 10,
when arguments were heard, and the magistrate, Mr. Vaughan,
reserved his decision. In giving that decision on Wednesday last,
Mr. Vaughan referred to the contention of the defence
that there was no power under the Statute for making a demand
for payment of services in returning undelivered papers to the
senders. He pointed out that a Treasury warrant had been issued
to that effect, and he held that such a warrant had the force of
an Act of Parliament. In the case under consideration
there were fresh duties imposed upon the Postmaster-General ;
fresh services were rendered ; and for those fresh services it was
perfectly clear that the claim of one halfpenny for returning each
paper was one in regard to which there could be no possibility of
refusal without an infringement of the law. Therefore, he must
make an order for the payment of the sum claimed, and the costs
of the summons.
258
PHARMACEUTICAL JOURNAL.
[March 20, 1897
THE WORLD Op PHARMACY.
- + - -
BUSINESS MEETINGS.
North Staffordshire and District Chemists’ Associa¬
tion, Thursday, March 11. — In December last a few representative
pharmacists of the North Staffordshire district convened a meeting
at Stoke-on-Trent, at which Mr. Glyn-Jones was present to ad¬
vocate the claims of the P.A.T.A. At the conclusion of the
meeting, which was A’ery successful and representative, it was
suggested that a chemists’ association should be formed for the
district for the object of advancing pharmacy, protecting the
legitimate trade interests, and promoting friendly intercourse
among the chemists and druggists. The value of such an associa¬
tion was at once and unanimously recognised, and then and there
steps were taken to ensure it being carried out. Mr. Edmund
Jones (Hanley) was asked to undertake the duties of hon.
secretary and the organisation of the association. The result
has been highly satisfactory, and on Thursday, last week,
a large number of the chemists and druggists of the dis¬
trict met at the North Stafford Hotel, and the previous
resolution was confirmed. Subsequently the following gentle¬
men were elected to fill the official positions for the first
year : — Alderman J. Averill, J.P. , Stafford, President ; Messrs.
J. W. Moore (Hanley) and F. Adams (Stoke), Vice-Presi¬
dents ; Edmund Jones (Hanley), Hon. Secretary ; and F. Weston
Poole (Newcastle), Treasurer and Librarian. The following were
elected to form the committee : — Messrs. G. Fisher, R. Prince, J.
Knight, W. Poole, C. J. Wain, T. Charles, J. F. Hewitt, S. C.
M’Kee, G. Viggars, T. C. Cornwell, D. H. Oxen, G. R. Hankinson,
W. Marson, R. G. Emery, F. Jacks, W. Jenkins, W. B. Allison,
W. Westhead, and F. Fowkes. Nearly forty gentlemen
offered their names for enrolment as members.
Pharmaceutical Society of Ireland, Wednesday, March
3.— The President, Mr. W. F. Wells, jun., in the chair. The
monthly meeting of the Council took place at 67, Lower Mount,
Street, Dublin, at three o’clock. There were also present the
Vice-President (Mr. Downs), Messrs. Grindley, Beggs, Professor
Tichborne, Dr. James, N. Walsh, Hayes, Conyngham, Bernard,
and Whitla (Belfast). — The President congratulated Dr. Walsh,
who had been co-opted a member of the Council, on his taking
his seat amongst them for the first time. — A letter from the Lords
Commissioners of the Admiralty informed the Council that it had
been decided, subject to the authority of Her Majesty in Council,
that licentiates of the Pharmaceutical Society of Ireland should be
eligible as dispensers in the Royal Navy. — A letter from the Local
Government Board dated February 13, intimated that Mrs.
Greer, who had received a contract for the supply of medicines
to the Granard Union, had, with the consent of the
guardians, withdrawn from that contract. — The President
said the objection of the Council to Mrs. Greer having
such a contract was that she was not qualified to sell poisons,
and the Local Government Board, by sanctioning such a
contract, would be lending themselves to an evasion of the law.
He hoped they would have no more of such contracts. The
President stated the conclusions arrived at by a Committee to
whom the subject of the awarding of medals to the best candidates
for the year at the Licence Examinations had been referred. They
recommended a gold medal to the best candidate who obtained not
less than 240 marks out of a possible 300, and also not less
than 65 in each of the separate branches of examination ;
and a silver medal to the second best candidate who scored not less
than 230 out of 300, and of 60 in each of the sub-divisions. The
Pharmaceutical Chemists’ Assistants’ Association had offered
to give two medals ; but the Committee were not in favour
of more medals, and thought that instead a third prize of books
should be given on minima of 200 and 55. The Committee, after
fixing the marks, had found that in two years, since 1893, six
candidates had scored over the minimum now fixed for the gold
medals. The highest marks obtained were 262 on the general total,
and 83, 90, and 89 in the separate branches. A discussion took
place as to whether the Pharmaceutical Chemists’ Assistants’
Association offer of a medal should be accepted. Some members
thought that to do so would lower the prestige of the Society, and
that the Council should do whatever was required in the matter,
the Association being recommended to give prizes to its own
members for work done by them. Eventually the recommenda¬
tion of the Committee as to the gold and silver medals was
adopted, and a resolution was passed, thanking the Association
for the offer, and recognising the spirit in which it had been
made. Other business having been disposed of, the Council
adjourned.
Pharmaceutical Chemists’ and Apothecaries’ Assis¬
tants’ Association of Ireland, Friday, March 5. — Mr. W.
McCarthy, L.P.S.I., President, in the chair. — Dr. J. A. Walsh
read an interesting paper on
Crystallography,
in which he described the origin of crystals, and the laws
governing their formation. The nomenclature of crystals was
given in detail, and their relationship to each other illustrated
by a series of examples. Diagrams of cubical crystals were also
shown, and the properties of the goniometer explained by means of
large coloured drawings.
School of Pharmacy Students’ Association, Friday,
March 12. — Mr. H. Marston Morgan in the chair. — The papers
arranged for the evening were “ Electricity,” by Mr. A. Miles,
and “ The Dispersion of Seeds,” by Mr. H. E. Matthews, but
the former was postponed at the author’s suggestion. Mr.
Matthews illustrated his subject with numerous specimens. At
the close Mr. E. M. Holmes, F.L.S., gave further interesting
details regarding these, and members engaged in a somewhat
animated discussion on controversial points raised by the paper,
all expressing their thanks to the writer for the interesting manner
in which the subject had been put before them. It was proposed
that the Association should hold a debate on some subject bearing
upon the calling of pharmacy. The choice of the particular subject
was left until the next meeting.
Chemists’ Assistants’ Association, Thursday, March 11.
— Mr. Charles Morley, President, in the chair. — In opening the
proceedings, Mr. Morley referred to the fact that the paper down
on the programme for that evening was one by Mr. Thomas Tyrer
on “ Scientific Education,” but owing to the recent painful cir¬
cumstance, whereby he had lost one of his sons, Mr. Tyrer did not
feel equal to giving his paper that night, but he had promised at
some future date to read it before the Association. When the sad
event occurred Mr. Peter MacEwan kindly promised to take Mr.
Tyrer’s place, and he would therefore bring before the meeting a
short paper on
Science and the Imagination.
Mr. MacEwan said that had time permitted, he would have
elaborated his remarks into something like “The Place of the
Imagination in Science and the Influence of Science on Imaginative
Literature,” but it was only possible that evening to gnaw the
bones of the matter. The common notion is that science is all
sober fact, without imaginative relief, and uninfluenced by
imaginative powers, hut the greatest scientific conceptions, those
generalisations or theories which have carved out fresh paths of
progress and research, are the conceptions of imaginative men.
From Aristotle to Newton in past generations, and from Darwin
to Kelvin in the present, there have been such men, whose thought
was as epoch making as their work. Mr. MacEwan after quoting
a passage from the writings of Edgar Allan Poe bearing on the
subject, then proceeded to show that many of the scientific leaders
and writers, such as Davy, Lavoisier, Dalton, Lord Kelvin, Kekule,
Van der Waals, Crookes, Lippmann, and Rontgen have been and are
reputed for their imaginative powers, and have by that influence
created new lines of practical effort, in which men just as competent
but less imaginative have failed. Referring to the wonderful in¬
fluence that imagination has had upon scientific literature, he men¬
tioned the efforts of Tyndall and the power he had to make abstruse
facts plain things to the uninitiated. So with Huxley and others.
Speaking of general literature and those who purposely use
scientific facts as the base of imaginative narrative, he instanced
the illusive power, analytical reasoning, and scientific insight of
Edgar Allan Poe, and regarded him as a master hand in this par¬
ticular cult. Possibly he derived his inspiration on the psycho¬
logical side from Voltaire’s “ Zadig” and the value of physio¬
logical facts from Mary Goodwin’s “Frankenstein,” but Poe was
a scientist as well as a tale writer, and astronomy, chemistry and
physics were as familiar to him as aeronautics, psychology and medi-
March 20, 1897]
PHARMACEUTICAL JOURNAL.
259
cine. Mr. MacEwan commented on the methods of Zadig and the
influence which they now have on medical diagnosis, explaining,
however, that the methods are much older than Voltaire. The
writings of Verne, Robert Barr, Conan Doyle, H. C. Wells, etc.,
were referred to, and passages of almost prophetic power quoted
to show that when exact knowledge is allied with imaginative
effort, the result appears convincing even to scientific persons.
The inaccuracies of some such writers were also touched
upon, and in conclusion he expressed the opinion that the
reason why so few novelists have handled science intelligently
and systematically is that a scientific training aborts imagina¬
tive tendencies ; the combination of the power of experi¬
mental accuracy and imaginative facility being rare. — Mr.
Morley in expressing his thanks to Mr. MacEwan, spoke of the
pleasure and interest with which he had listened to the paper.- —
Mr. Tickle added his thanks to those of the Chairman. He was
struck by the fact that so many scientists are non-imaginative,
and that imaginative men are usually not good workers ; he thought
Mr. W. Crookes to be one of the exceptions to the rule, as he is not
only a good worker but must also be an imaginative man. — Mr. C. J.
Strother, after having read the lifeof Edgar Allan Poe, who had been
referred to by Mr. MacEwan, had come to the conclusion that his imag¬
ination was fed largely upon alcoholic spirits, and he thought Poe’s
example in that direction was not one to imitate. — Mr. E. W. Hill,
Vice-President, said he had expected to hear a satirical view of
the connection between imagination and science, the general idea
being that in the advancing knowledge of the present day there is
no scope for the imagination. He, however, believed it to be the
inventive faculty which enabled great men to bring forth new
light on scientific subjects, although sometimes men allowed their
imagination to carry them to ridiculous conclusions.— Mr.
MacEwan briefly replied to the remarks made by the speakers,
after which a vote of thanks was accorded to him for his paper.
Proprietary Articles Trade Association, Wednesday,
March 10. — -Meetings of the Manufacturers’ and Wholesalers’ Sec¬
tions were held to elect respective representatives to Council.
Result : — Manufacturers : Messrs. M. Beetham, Cheltenham ; J.
E. Garratt (Frog in Your Throat) ; W. A. Gilligan (Liebeg’s Extract
of Meat Co.) ; H. J. Hall (Stephen Smith and Co.) ; H. S. Norris
(Condal Water Co., Ltd.); Thos. Powell, Ltd., Vitalia Co., W.
Lambert and Co. Cha§. Sanger); Bovril, Ltd. (J. Shorrock). Whole¬
salers : Messrs. Barclay and Sons, Ltd. ; Bleasdale, Ltd., York;
Butler and Crispe, London ; Evans, Gadd and Co. , Exeter ; Hirst,
Brooke and Hirst, L -eds ; Maw, Son and Thompson, London ; Morris
and Jones, Liverpool ; John Sanger and Sons, London ; W. Sutton
and Co., London; Jas. Woolley, Sons and Co., Manchester.
Retail Section : The voting papers for the election of this section
were counted by Mr. G. R. Barclay, and Mr. W. W. Goodall,
Chemist, Fulham Road, with the result that the following ten
gentlemen were elected : —
W. Jones, Birmingham
J. Cocks, Stonehouse . .
S. N. Pickard, Bradford
H. W. Seely, Halifax . .
J. Williams, Manchester
774
751
737
71S
707
A. Cooper, South Kensington . . _
W. R. Barnes, Upton Manor .
T. P. Garrett, Newport . _ ..
P. Rowsell, Exeter .
T. S. Wokes, Liverpool .
The first eight were members of the retiring Council.
088
044
613
501
553
Western Chemists’ Association (of London), Wednes¬
day, March 17. — Mr. J. W. Taplin, President, in the chair.— The
business of this meeting was to discuss the new bye-laws proposed
by the Council of the Pharmaceutical Society. The subject
attracted a fairly large assembly. Amongst those present were
Messrs. H. Cracknell (Secretary), J. C. Hyslop, J. H. Mathews, G. S.
Taylor, W. Warren, F. Andrews, R. H. Parker, Davis, A. C. Wootton,
Dr. B. H. Paul, E. Marsh, P. MacEwan, Philips, and others. —
The President, Mr. Taplin, before opening the discussion,
announced that he had received three telegrams from Messrs.
W. Martindale. R. Bremridge, and C. Morley, expressing their
regret at not being able to be present.
The Proposed New Bye-Laws.
Mr. Taplin then said the topic for discussion this evening,
the proposed new bye laws of the Pharmaceutical Society,
is one, I believe, over which there can be but little diversity
of opinion in the trade. Every chemist to whom I have had
the opportunity of mentioning this subject has expressed
himself in favour of these proposals. Whatever our opinions
may be respecting this subject, it will be well to ap¬
proach it with a calm and judicial frame of mind. No doubt
the proposed new bye-laws have come as a surprise, a pleasant
surprise, I hope, to the majority of chemists. That they will meet
with general support and approval almost goes without saying.
The abolition of our First examination and the substitution of one
more comprehensive and by thorough approved examining bodies will
be of great advantage to the pharmacist of the future. It is to be
hoped that the Pharmaceutical Society will see its way to add the
very necessary proviso that three years shall elapse between the
registration of the student and the time when he will be allowed
to present himself for the Minor examination. In nearly every
instance the future candidate will have passed the examination
required for his registration as a student when at school and before
entering the calling of a pharmacist, thus leaving most of his sub¬
sequent time during the three years he has to be practically engaged
in the translation anddispensingof prescriptions free for that purpose
and for shaping his studies for the Minor, which he will be eligible to
pass as at present at the age of 21. No doubt every gentleman here
has read of the extended scope the First examination is to take, and
the footing the candidate will be placed upon. At a later date
should he wish to enter either the medical, dental, or veterinary
profession, the Preliminary that will satisfy the Pharmaceutical
Society will also satisfy the examiners of any one of those Societies.
The second proposal which we have to consider is that of increasing
the fee for the Minor from five to ten guineas after the year
1898. Up till that time the present fee of five guineas
will hold good, but in 1899 the increased fee will be ten guineas.
Personally, I should like to see the increased fee deferred until
1900 ; it would then enable any student now on the Register to
present himself for examination at the reduced fee. The Council
in its wisdom has come to the conclusion that the lower fee is
an insufficient sum for the purposes of examination, registration
and subsequent protection of a man from unqualified opposition?
Since 1868 the Pharmaceutical Society has held a very different posi¬
tion to what it held prior to that date. In 1868 the Pharmacy Act
became law and the Society a State Institution, drawino- its
revenues from several sources, principally from the examinations
registration fees, and the subscriptions of members, associates and
students. Everyone will admit that for the work it is doing it must
have a plentiful supply of the sinews of war. Who should find these
supplies ? Certainly those who desire the benefits of registration
and protection. After all, twelve guineas as the inclusive fee for
registration as a student, and then the examination and registra¬
tion as a qualified chemist, is not much to demand when one
remembers for that sum of twelve guineas the Society protects the
chemist from the unqualified trade for the whole time his name is
upon the Register without getting another sixpence from him, and
we cannot shut our eyes to the fact that it is a much more costly
affair to administer the Pharmacy Act now than it was. The many
prosecutions which have taken place, and those that will have to
be undertaken, are from a pecuniary point of view carried out at a
great loss to the Society. I am sorry to find that one of our prin¬
cipal journals has attacked this question with a bias one would
hardly expect from such a quarter. In the Chemist and Druggist
I note the Society is charged with the serious offence of aim i no- at
adding to the features of its own J ournal the characteristics of a
trade newspaper, and that in so doing the income provided by
increased fees has been swallowed up, with the result of a financial
fiasco. The Chemist and Druggist need have no apprehen¬
sion about the financial position of the Pharmaceutical Journal.
Everyone who knows anything about it knows that the Pharma¬
ceutical Journal is on a sound basis, and is repaying for the
capital sunk in order to make the Journal fulfil the conditions of
being the first Pharmaceutical Journal in the world, as Mr.
Carteighe told the last annual meeting. If my memory is not
treacherous ; he also expressed the opinion that it was not desirable
to publish every detail respecting the working of the Journal.
The Pharmaceutical Journal is the official organ of the Society,
and if the Society sees fit to do all in its power to increase its
circulation by fair means, so as to assure its financial success, so
much the better for that Journal. Why the Pharmaceutical Journal
should be singled out for attack I cannot conceive, it reminds me
somewhat of the old adage, if you have no case abuse the other
side. He then moved the following resolution : —
“ The Western Chemists’ Association of London, having read and considered the
proposed new bye-laws of the Pharmaceutical Society, are in full accord
therewith. They beg to tender their hearty support and co-operation in the
efforts of the Pharmaceutical Society to advance the education and interests
of chemists generally.”
. Mr. Warren briefly seconded the resolution,
260
PHARMACEUTICAL JOURNAL.
[Maech 20, 1897
Mr. R. H. Parker led off the discussion, and in an admirable
speech expressed his cordial approval of the alterations. He advo¬
cated a higher and more stringent examination, both for the Pre¬
liminary and the Minor, and was in favour of a registration fee being
fixed which would cover all the expenses which naturally arise
during the time a man is connected with the trade. Personally,
he preferred the payment of a lump sum of £21 when a man passed
his examinations, which should not only put him on the Register,
but make him, de facto , a member of the Pharmaceutical Society
for life. — Mr. Wootton came next, and endeavoured to show that the
Pharmaceutical Council, in making the proposals was actuated by
self-interested motives, and not for the benefit of the trade generally.
He was of opinion that it required the increased revenue to help
in running the Pharmaceutical Journal in unfair competition
with its rivals. He pointed out that already the members of the
Society, in return for their yearly guinea subscription, received
back, in the shape of the Journal, etc., value to the extent of at
least 17s. per annum, and occasionally as much as 35s., which he
contended was not right, as it must come from the surplus left
over from the examination fees. — Mr. J. C. Hyslop, in a quiet but
effective speech, repudiated the idea that the Pharmaceutical
Society was working for its own interests, such statements, he
said, had been made for the last forty years but were never proved.
He was in entire accord with the proposals, and could not under¬
stand why the other trade journals should so bitterly oppose them,
until he saw the expression “ Unfair Journalistic Competition.”
Then he saw through the opposition. He could understand jealousy
among children, but such jealousy as was betrayed in the articles
which had appeared in the Chemist and Druggist and the
British and Colonial Druggist he could not understand ; com¬
mercial rivals should be more generous and manly. He referred in
high terms to the good work done by the Society in the past, and
could see no reason why those who in the future were to
reap the benefits of the Society’s labour should not
contribute their share of the expense. — Mr. Davis also upheld
the propositions of the Council, although he thought the passing
of a good Preliminary examination was no criterion of a lad’s
ability to pass the future examinations. With reference to the
£10 10*'. fee, he did not see why it should be postponed until
1900, as suggested by Mr. Taplin, but thought it should
come into force immediately. — Mr. Andrews was entirely in
accordance with the proposals of the Council with regard to
the Preliminary examination, but had not come to any definite
conclusion with respect to the higher fee. — Mr. W. Warren
thought the higher fee would press hard on no one, and that all
who paid the fee would get their money’s worth. With reference
to Mr. Wootton’s remarks, he thought they were a splendid ad¬
vertisement for the Society’s Journal, especially when he stated
that the members get 35s. for their guinea. Mr. Wootton had
imputed a motive to the Council, but he (Mr. Warren) was of opinion
there seemed to be more motive in the journalistic opposition. —
Mr. Marsh quite approved the alterations, and made a suggestion
to the effect that when the higher fee of £10 10s. came in force
each newly registered man and student should have the Pharma¬
ceutical Journal sent to him free for at least twelve months. — Mr.
Davis supported that suggestion, as he believed it would be a
great help to men working for the Major examination, and would
be an incentive to them. — Mr. Taylor heartily agreed with the
proposals of the Council, and condemned in very scathing
terms the journalistic attacks that had been made. All
whom he had spoken to about the increased fee believed it to
be the right thing. He expected that those who never did
anything but say disagreeable things about the Society would
oppose it, and these very men would also be the first to ask to be put
on the Benevolent Fund when they were in trouble. — Dr. Paul said
some of the speakers had suggested a registration fee instead
of an examination fee, and he wished to point out that the
fee now paid is like the examination itself, one of the two condi¬
tions necessary for registration. — Mr. Phillips spoke in favour of
the alterations, and the resolution was then put and carried
without a dissentient vote.
The Approaching Council Election.
Mr. Andrews brought forward a matter connected with the
election of Councillors, and asked those present to do all they
could to return more London members to the Council. At present
the work pressed very heavily on the few Londoners, and it was
necessary they should be better represented.— The names of
Messrs. Parker, Hyslop, Warren, and Phillips were mentioned
for nomination as candidates.
SOCIAL MEETINGS.
Bristol Pharmaceutical Association, Wednesday,
March 10. — The first dinner of the members of the Bristol Phar¬
maceutical Association took place at Stuckey’s Restaurant, and
was a great success. The President", Mr. B. Allen, was in the
chair, supported by Councillor Bennett, Messrs. Algernon Warren,
Moss, Hermann, Stroud, Cole, White, J. Chandler, J. G. Plumley,
G. T. Turner, Dibble, Sleight, Barry, R. R. Groome, Hart
(Clevedon), H. J. Dalgleish, J. T. Good, Moore, G. W. Isaac,
B. Keen, T. Buxton, W. Hickman, E. Young, Nethercott, J. T.
Davies, J. Evans, E. Whiston (Bath), L. Vigis (Bath), Pitchford,
J. Allen, F. W. Wintle, H. E. Boorne, F. Luxton Jennings,
Berry, Troake, Jones (Birmingham), Smith, etc. Apologies for
absence were read by Mr. Keen from Mr. Walter Hills, President
of the Pharmaceutical Society (who also sent a telegram of good
wishes), Mr. Chas. Townsend, and Mr. Park (President of the
Plymouth Association). — The President gave the usual loyal
toasts, after which Mr. E. Young submitted that of
“ The Pharmaceutical Society of Great Britain.”
He had a feeling of sincere loyalty for the Society, and believed
that any advance in pharmacy must come from the Society. It
was democratic in its constitution, and he hoped to see Associates
swelling the number of the Council. He thought it was their duty
to support the Society on these grounds, and because it was a
terror to evil-doers and administered the Benevolent Fund without
charge, not even as much as the 1| per cent, that the Indian
Famine Fund cost to administer. He coupled the toast with the
name of their respected Hon. Sec., Mr. Keen, who in strict con¬
fidence had told him that the response was a load upon his mind. —
Mr. B. Keen replied. He was very much in the position of the
man who was bathing and lost his clothes, for Mr. Young had
stolen his speech. He had but recently taken up the local secre¬
tary’s duties, and really their old friend Mr. Stroud ought to have
been responding. But after a, history of fifty years there was no
need for justification of the Society. Its aims and objects were
well known. It was not, and never had been, a mere trades union.
It was something higher and better than that, while he believed,
if properly interpreted, it would include that too. Its objects had
been to elevate the individuals who practised pharmacy in educa¬
tion in its broadest and most liberal sense — scientific, moral, and
intellectual — -in the belief that if t.ie individual were
raised, so the corporate body would become more respected
and successful. That was necessarily a work of time.
It was not thirty years since the Pharmacy Act was passed, and
while that was a long time in the life of an individual, it was not
long in the life of a society of that kind, and if they compared the
past with the present, they would have to admit that some pro¬
gress had been made. There were giants in those days, but taking
the average run of chemists of those days and comparing them
with the average men of to-day they must admit that there was a
higher type, and that a great advance had been made in culture
and refinement. There were those who asked “ Why should I join
the Society ? It would be no pecuniary benefit to me.” He would
reply that it was not everything that could be measured by pounds,
shillings, and pence, and that it was something to be associated
with a society which had such high aims. It was easy to criticise
the Society, but it was better to join the Society and help to
form its policy and share in its work. The proportion of chemists
in Bristol who were members of the Society was very large, and
indeed, if he went to look for new members he hardly knew where
to go. Bristol had between forty and fifty subscribing members.
Referring to the work of the Society, he said it kept the Register,
which was no small thing, because it gave members of the craft
their legal status. It conducted prosecutions at a great
cost for the benefit of all members of the craft, and
it managed a Benevolent Fund, every penny of which
went to the object for which it was given. In a
meeting of chemists nowadays it was customary to speak in a
pessimist strain, and to say that they were all going to the dogs.
He thought, however, that there was still room for the conscien¬
tious and painstaking educated pharmacist. They must be
educated men, and they must combine among themselves to do as
they would be done by. He would ask them to avoid any personal
identification with the rampant patent medicines of the present
day. He did not say they were not to sell Cockle’s pills, or
Seigel’s syrup— they could not help it — but let them avoid too
March 20, 1897]
PHARMACEUTICAL JOURNAL.
261
close identification with those goods. It was not for the welfare of
pharmacists to do so. — Mr. Algernon Warren gave
“ The City and Trade op Bristol,”
and observed that if the drug trade had not advanced in propor¬
tion to other trades it must be owing to the abnormal health of the
city. — Councillor Bennett replied, and referred to the great
growth of the city in the last forty years. — Mr. G. T. Turner
proposed “ The Visitors,” and offered a hearty welcome to
them. — Mr. Whiston (Bath), and Mr. Vigis, of the same city,
replied, the former suggesting a doubling of subscriptions to the
Benevolent, Fund for this Diamond Jubilee year. — Mr. J. G.
Plumley proposed “ The Bristol Association,” and after a reference
to its educational work said now that it had been taken up by
other educational bodies, they had decided to meet quarterly and
discuss trade questions, to which meetings he invited Bath
chemists. — Mr. J. Chandler having replied — Mr. Jones spoke of
the work of the P.A.T.A. in Birmingham, and advised chemists
to join that Association. — Mr. T. Buxton gave “ The Chairman,”
and that concluded the toast list. Some excellent music was
provided by a glee party.
North Staffordshire and District Chemists’ Asso¬
ciation, Thursday, March 11. — At the conclusion of the meeting,
reported on page 258,
The Inaugural Dinner
of this Association was held in the Large Hall of the North Staf¬
ford Hotel. The chair was taken by Alderman J. Averill, who
was supported by Messrs. W. Go wen Cross, J.P. (Shrewsbury),
Rymer Young (Warrington), Councillors of the Pharmaceutical
Society ; F. Adams (Stoke), and J. W. Moore (Hanley), Vice-
Presidents of the North Staffordshire Association ; Edmund Jones
(Hanley), Hon. Sec. ; M. Conroy (Evan, Son and Co., Liverpool),
F. J. Gibson (Wolverhampton), President of the Midland Associa¬
tion ; F. H. Alcock (Birmingham), W. Prosser (Birmingham), W.
Brinson (Liverpool), T. C. Cornwell (local secretary for Hanley),
I. H. Heap, J. D. Furnival, J. H. Waldron, W. Elmitt, R. T.
Christopher (Hanley), R. G. Emery, R. D. Holt (Stoke), R. Prince
(Longton), — Hemingway, W. Jenkins, F. Jacks (Stone), W. Marson,
W. Westhead, F. Fowke (Stafford), C. J. Wain, D. H. Oxen, — Hale,
W. Poole, — Saunders (Newcastle-under-Lyme), T. Charles (Burslem),
G. Viggars, S. C. M’Kee (Tunstall), G. R. Hankinson (Uttoxeter),
W. Goodman (Eccleshall), Dr. Hind (Stoke), and W. B. Allison,
(N. S. Infirmary). — The Secretary read a large number of letters of
apology and congratulation. Mr. Walter Hills, President of the
Pharmaceutical Society, wrote : “lam much obliged to you for
your kind and cordial invitation to be present at the proposed
meeting and dinner of the North Stafford Chemists’ Association.
I regret, however, that circumstances do not permit me to accept
it.” Mr. Hills remarked that his regret was lessened by the
fact that Messrs. Cross and Young would expound to them, with
ability and earnestness, the benefits accruing to the trade by the
existence of the Society — benefits which would be still greater and
more generally felt if it had more loyal support from all on the
Register of chemists and druggists. Mr. Bremridge, Secretary of
the Pharmaceutical Society, wrote expressing his pleasure that the
chemists and druggists of North Staffordshire recognised the
dangers of isolation and had determined to associate themselves
locally in one body. He hoped that the Association would
in time become a potent factor in effecting the long hoped for
union among British pharmacists, for which the Society had so
long worked. Mr. G. S. Woolley (President Manchester Chemists’
Association), while being unable to be present, owing to illness,
wished every success to the Association, feeling that the chemists
were acting wisely in binding themselves together for mutual
protection. — The Chairman, in proposing “ The Queen, the Prince
and Princess of Wales, and the rest of the Royal Family,” com¬
menced a series of what proved to be excellent after-dinner
speeches. He referred to the fact that shortly the record reign
would be celebrated, and said that chemists and druggists should
be as enthusiastic as any other body of men over the event, because
during the time the Queen had sat on the Throne more advance
had been made in science and commerce than at any previous
period in the history of the country. — Dr. Hind next gave —
“Success to the Pharmaceutical Society.”
He said he had often met in the room in which they were then
assembled members of the profession to which he belonged. They
had a somewhat kindred society to the one which they were then
inaugurating, and he hoped the North Staffordshire Chemists and
Druggists’ Association would be as successful in the purposes for
which it was formed as the one to which he belonged. He had no
doubt it would be. Neither did he doubt that it would be a great
power for political reform, there were many things that Parlia¬
ment would have to do for chemists and druggists. His Associa¬
tion had shown that union was strength, and that nothing could
be done by isolation. The more one met with one’s
rivals the more corners were rubbed off, and stupid
rivalry was changed into friendly competition. He coupled with
the toast the names of Messrs. Cross, Young and Cornwell.
Mr. Cross, in responding, referred to the kindness that had been
extended to him personally, and the enthusiastic manner in which
the toast of the Pharmaceutical Society had been received. In
some assemblies the toast was not received so cordially, and the
reason was not very difficult to see. It was simply because the
majority of chemists knew so little about the work of the Society,
and they did not keep in touch with it, although it was doing all
it could for the chemists and druggists, whether they were
members of it or not. Such societies as the North Staffordshire
would do much to remedy that feeling of indifference, because it
would keep them closer in touch with the parent society in London.
He once knew a very eloquent pharmacist, who, on being taken to
task for the apathy he displayed towards the Pharmaceutical
Society, said “Well, what has it done for me ?” He (Mr. Cross)
asked him if he was a member of the Society, and receiving a reply
in the negative, asked him what the Ancient Order of Foresters or
any other society would do for him if he was not a member. But
the fact was that the Pharmaceutical Society did very much for
those who were not members and were not really entitled to be
benefited by it.
Many Hours op Anxious Deliberation
were spent in benefiting the trade generally. He had only to refer to
the fact that unqualified traders met with no partiality and no very
kind treatment from the Council, which punished them on every op¬
portunity, to show that the legitimate chemists were protected by
the Society. They had local secretaries in all the centres, and any
report as to illegal practices was investigated. The lawyer’s
bill was about a thousand pounds per annum, a fact which showed
that the trade was getting something from the Society. It had been
hoped that chemists and druggists would secure exemption from
serving on juries, but intelligent jurymen were so difficult to find
that he thought it likely they would have to enjoy the privilege of
being summoned a little longer. After referring to the new Asso¬
ciation in hopeful terms, Mr. Cross spoke of the advisabilty of
closely
Cementing the Union
between themselves and the medical men. They had a great deal
in common. Some chemists might object to medical men dispen¬
sing their own medicines, but the medical profession was over¬
crowded, and some of them had to do so to gain a living. It was
no reason for quarrelling with them. In conclusion, he wished
every success to the new Association, to which he would always be
willing to render assistance.
Mr. Rymer Young, in adding his thanks for the manner in
which the toast had been received, also spoke of the benefits
which outside chemists received from the Society for which they
did not pay. He referred jocularly to the cycling assistants, and
said that if they could find money to buy bicycles he did not see
why they could not find ten pounds to have their names on the
Register for ever and ever. Touching upon the question of the
proposed alteration in the matter of
The Preliminary Examinations,
he said that at present the examination could be passed by any
Board School boy of the fourth or fifth standard, or at any rate
such a boy would be expected to be able to pass it. He did not
see any reason why the alteration which would take place in
1900 should not be brought about at once. The alteration would
do away with a great deal of the scandal which undoubtedly was
attached to their trade, because that scandal was caused to a great
extent by illiterate boys being taken as apprentices who, although
they might ultimately pass their Preliminary, could not possibly
get through the “ Minor.” It was these lads who eventually became
the men who sold everything but the scheduled poisons. If the en«
262
PHARMACEUTICAL JOURNAL.
[MAech 20, 1897.
trance examination was made stiffer, that would be done away with.
— Mr. T. C. Coen well said that since he joined the Pharma¬
ceutical Society, twenty-five years ago, he had never been able to
follow its work as closely as he could have wished, but he had ever
recognised that it was doing a good and beneficial work. A great
many of the trade had no idea of the benefits. In one year alone,
one man in that district had had to pay fines amounting to £25 for
practising illegally. He was most gratified by the proposed change
in connection with the Preliminary, and the only drawback, as
Mr. Young had said, was that it could not come into operation
for three years.
Mr. F. J. Gibson proposed
“The Noeth Staffoedshiee Chemists’ Association,”
and said that the meeting augured well for the future suc¬
cess of the Association. — The Peesident, in responding, said he
believed the Association would prove of great advantage to them
in their several tradings. It would enable them to discuss measures
for the advancement of the trade, and may be they would be able
to strengthen the hands of the Pharmaceutical Society. He thanked
Messrs. Cross and Young for their attendance as representatives
of the Council of the Society, and expressed his conviction
that the more they knew of the doings of that Society
the more they would appreciate its existence and the privilege
of membership. — Mr. E. Jones, Secretary, also responded.
He hoped he would always be able to give the Pharmaceutical
Society the support it deserved, and was sorry that it was not
always so unanimously supported as it was that night. — Mr.
Moeson gave the “Medical Men,” Messrs. W. P. Oulton and
W. Allison (North Staffordshire Infirmary) , responding. —
“ The Visitors ” was proposed in a neat speech by Mr.
J. W. Mooee, and Messrs. Peossee (Birmingham), M.
Coneoy (Liverpool), and F. Haeeis Alcock (Birmingham)
humorously replied. — “The Wholesale Houses” and “The
Ladies” were given by Messrs. C. J. Wain and I. J. Heap
respectively. Messrs. W. Beinson (Evans, Son and Co., Liver¬
pool) and C. Aedwinckle (Messrs. Hirst, Brooke and Hirst)
responding for “The Wholesale Houses,” and Messrs. Peince,
Elmitt, and It. Cheistophee for the fair sex. — Mr. Aedwinckle,
following the offer of £5 from a member, promised a guinea on
behalf of his firm and another from himself towards starting a
library in connection with the Association. — During the evening
songs were given by Messrs. C. L. Forrester (Royal Apollo Glee
Singers), T. C. Cornwell, E. Jones, and W. Brinson, and Mr. D. H.
Oxen gave several recitations, a very convivial time being spent.
It was the unanimous opinion of the gathering that the meeting
was the most successful, enthusiastic, and enjoyable of the kind
ever held in North Staffordshire.
Aberdeen Junior Chemists’ Association, Tuesday,
March 9. — To mark the close of a very successful season, a
Cinderella dance was held in the Royal Hotel. The ballroom was
prettily decorated, and dancing commenced at 8.30, a large
company being present. Music was furnished by Mr. G. Wright’s
band. Mr. M. K. Booth acted as M.C. , while Mr. Charles Philip
was Secretary of the Committee of Arrangements. A very enjoy¬
able evening was spent. Photographs have been taken of the
Association Committee placed in a group. The original picture
is to be presented to the senior association, and large-sized repro¬
ductions of the same will be for sale at 2-s. fid. each, Mr. J. Porter,
of Hardie and Co., being the photographer.
Edinburgh Pharmacy Golf Club, Wednesday, March 10.
—Mr. James McBain, President, in the chair. — This was the first
meeting of the Golf Section of the Edinburgh Pharmacy Athletic Club
on its new basis as a fully constituted golf club. The following office¬
bearers were elected : — Captain, John Greig ; Vice-Captain, Thomas
Welsh ; Secretary, David Harley ; and as members of Committee,
Messrs. Gibb, Birnie, Forret, Walker, and Horsburgh. The rules
were then considered and revised, and it was decided that no extra
sum should be paid over and above the annual subscription to the
Athletic Club, the Committee of the latter having undertaken to
defray all the expenses. It was intimated that in addition to the
present trophies a medal would be presented for competition by
Mr. David McLaren.
PARLIAMENTARY NOTES AND NEWS.
The Committee of Council on Education is a body concern¬
ing which much speculation has been indulged in. The mystery
surrounding its composition, however, has now been dissipated
by Sir J. Gorst — the Vice-President — who, in reply to Mr. Carvell
Williams, disclosed the personnel of the Committee as follows : — The
Lord President, Marquis of Salisbury, the Secretaries for the
Home, Colonial, and War Departments, the Chancellor of the
Exchequer, the First Lord of the Admiralty, and Sir John Gorst.
There would seem to be some ground for the taunt that the essen¬
tial qualification for a seat on the Committee is an entire absence of
knowledge of matters pertaining to public education. The House
has a keen sense of the ludicrous, and received Sir John’s announcement
with evident enjoyment. Mr. Carvell Williams attempted to still
furtherdraw the Vice-President by asking if the Committee ever met,
but the effort was futile. It is a singular thing that though there
are among Privy Councillors men of high scientific attainments
and educational experience, the Committee of Council nominally
charged to watch over Public Education is a mere departmental
amalgamation of ministers, whose chief official interests lie
outside education altogether !
The Postal and Telegeaph Seevice is to reap the benefit of
the facilities for rapid transmission and delivery offered by the use
of the bicycle. Mr. Hanbury, as the representative of the
Postmaster-General, has stated that two systems are being
tried in twenty-two provincial towns — in the one system the
machines being provided and maintained by the Post Office, and,
in the other, being obtained by and belonging to the officer using
them. The use of cycles in the delivery of telegrams in country
places will greatly reduce the present charge of one shilling a mile,
and the authorities have arranged to substitute, when practicable,
a messenger mounted on a cycle for the present horse-mounted
man, and to charge at the rate of fourpence a mile.
Select Committees are the order of the day. The latest is the
assembly of gentlemen appointed to inquire into the working of
the Merchandise Marks Act, 1887, the provisions of which do not
seem to act in such a beneficial manner as the commercial
community ten years ago anticipated they would. Naturally, Sir
Howard Vincent is a member of the Committee, and he will no
doubt urge the merits of the Bill which was introduced by him
early this Session, and ignominiously rejected by the House. The
Committee consists of ten Ministerialists and six of the Opposition,
and met for the first time on Friday for formal business.
The Peteoleum Committee is meeting twice a week now. At
a recent meeting Mr. Coroner Hicks was examined, and expressed
himself with characteristic vigour against the deadly paraffin lamp
of the earthenware reservoir type. Metal holders, says Mr.
Braxton Hicks, should be the only kind allowed.
The Vivisectionists have a champion in Mr. Swift MacNeill, the
Nationalist member for South Donegal. On the 12th inst. he asked
for an explanation of the official report for 1895, from which it
appeared that 200 or 300 animals were tortured in a single
experiment. He also wished to know generally the nature of the
supervision exercised by the Home Department in respect to
experiments performed by licensed persons on living animals.
The reply of the Home Secretary should dispel all suspicion
in right-minded people that the certificates of the
Department are abused or made use of to cover the
perpetration of gross and unnecessary cruelty. The number of
animals used is not in excess of the experiments made, but in fact
rather less. Inspectors both inspect registered premises, and are
often present during the performance of experiments ; moreover,
they see the bodies of the animals on which experiments have been
made and are in a position to report any irregularities. Certificate
A (permitting anaesthetics to be dispensed with) is never issued
except for trivial operations, and in every case precautions are
adopted to prevent unnecessary pain. The chief safeguards against
abuse of the privileges granted under the licence are to be found,
said the Home Secretary, in the character of the persons holding
the licence, and in the stringent conditions under which such licences
are given, which it is the duty of the inspectors to see observed,
March 20, 1897.]
PHARMACEUTICAL JOURNAL.
263
SOME NEW IDEAS.
LETTERS TO THE EDITOR.
CHEAPER SANITARY TOWELS.
The value of Southall’s “Sanitary Towels” has been long
'established, and the introduction of a “towel” to be sold at a
halfpenny (less than the cost of washing) should enable them to be
used by all classes. Southall Brothers and Barclay have had
large experience, extending over many years, with absorbent
materials of all kinds, and the fabric of which their new “ sani¬
tary towel” is composed possesses the necessary qualities in a
.marked degree. This material is manufactured under a Pro¬
visional Patent (No. 20,040), from a mixture of finely divided
cellulose and “ dimatos,” the newly-discovered infusorial earth,
for the handling of which Southall Brothers and Barclay hold
the sole right throughout the world. The “ dimatos,” which is
lighter than magnesia and capable of absorbing more than six
times its weight of liquids, is very intimately incorporated with
the cellulose, and the resulting material, in addition to being
Highly absorbent, possesses remarkable diffusive properties, so that
when enclosed in an envelope of absorbent wool wadding it forms
a pad peculiarly well adapted for the purpose for which it is
intended. Instead of losing its soft and elastic properties and be¬
coming pulpy when wet, Southall Brothers and Barclay’s patented
material possesses all the valuable diffusive properties of cellulose,
combined with the elasticity of absorbent cotton. The introduc¬
tion of the halfpenny “ towel,” made from this material, supplies a
want, the existence of which is obvious, and it should soon acquire
the popularity which it deserves.
DEVONSHIRE CREAM AND MALT EXTRACT.
A preparation containing twenty-five per cent, of the richest
Devonshire cream, incorporated with malt extract, is offered by
Messrs. Evans, Gadd and Co., of Exeter, as a substitute for
cod-liver oil, under the name of “ Ambrosia.” It is well made
and extremely palatable, and put up in wide-mouth, stoppered
bottles to retail at half-a-crown each. These are enclosed in
dainty cardboard cases, and supplied to retailers on very favourable
terms, whilst the article is included in the P.A.T.A. list, so that
the profit will be protected.
SOLIDIFIED SOUPS.
Anything bearing the name of Messrs. E. Lazenby and Son may
be expected to prove of excellent quality, and only a minimum of
•courage is required, therefore, on the part of anyone who thinks of
experimenting with the firm’s “ Solidified Soup Squares.” These
are prepared with a beef basis, and are intended for the speedy
improvisation of soups of all kinds — mulligatawny, pea, julienne,
, green pea, haricot, carrot, household, etc. From any one of the
“squares,” which retail at sixpence each, a pint and a half of
excellent soup can be prepared in less than half an hour.
USEFUL INFORMATION AS AN ADVERTISEMENT.
Messrs. Thomas Christy and Co. send a copy of a small
•pamphlet entitled “ Nuggets,” which they have recently published
with a view of increasing the sale of Messrs. Stearns’ Wine of Cod-
Liver Oil. In addition to information concerning the wine, various
.useful facts are interspersed throughout the pamphlet, and chemists
in various parts of the country who stock the preparation referred
to may, on application, have as many copies free as they can
judiciously distribute.
CHARITY, ART, AND HUMOUR.
The Leeds Poor Children’s Summer Holiday Fund has for its
object the provision of a three weeks’ summer holiday in the
country for delicate children of poor parents. The average cost is
less than twenty shillings per child, but though the expense is
small the boon conferred is great. In aid of the Fund, Mr. Fred
Reynolds produces every year a ‘ Comic Guide to the Leeds City
Art Gallery,’ which is sold at sixpence per copy, and the nett
result of the sale in previous years has amounted to £15 13s. 9 d.
This year’s production is extremely funny, and one could almost
imagine the originals of the caricatures themselves laughing at
these grotesque and very counterfeit presentments.
The Benevolent Fund Special Appeal.
Sir, — At a meeting held in Manchester, on W ednesday, March 10,
to consider the best steps to take to augment the Benevolent Fund
in commemoration of the sixtieth year of the Queen’s reign, it was
unanimously decided to form a special fund, to be called the Man¬
chester and District Chemists’ Assistants’ and Apprentices’ Dona¬
tion to the Benevolent Fund. It was also resolved that, as far as
possible, a personal call should be made on every assistant and
apprentice in the district to solicit donations thereto. And that an
endeavour should be made to increase the number of annual sub¬
scribers to the Benevolent Fund. To give effect to these resolu¬
tions the following were elected as a committee, with power to
add to their number : — ■
J. Bates.
L. N. Burch.
R. G. Gourlay.
A. Midgley.
A. Ogden.
H. Oldhaih.
G. W. Overend.
W. Rimming-ton.
Hon. Sec., J. Riding.
A preliminary list of donations will appear in a subsequent issue
of the Journal. Donations will be received and transmitted by
any of the above-mentioned committee.
March 11, 1S97. J. Riding.
When is Food Taken ?
Sir,— You have kindly opened your columns to students, with¬
out restriction of age, so far as I can learn, and you answer many
various questions. Would you tell me when “ food ” is taken ? I
notice that younger members of the Faculty, especially, have
taken to translating the hard words in prescriptions, I suppose out
of consideration for the infirmity of dispensers, as it cannot be any
defect in their own stiffer and stiffer education. So that we get
directions of this sort — “ Sumt. fss. ex aquae between meals.” It
is generally “ ex aquae,” unless the quantity is specified, and
then it is “ex aqua §ss.” ! !
Hybrid directions of this sort present no practical difficulty,
because the dispenser can render the sentence into good English.
But when the man of science and all knowledge writes “ A table¬
spoonful to be taken three times daily after food,” it would be pre¬
sumptuous to depart from his ipsissima verba, which the patient
can read. And yet I cannot understand the terms. “After
food” is not an English expression. I can only imagine that
it is a translation of “post cibum” or “ cibos,” as older physicians
used to write, and we used to translate “after meals” periods of
fairly regular recurrence inmost households. But “food,” what
is it ? and when taken ? Some people say alcohol is poison, and
others say it is “ food.” Is medicine to be taken after a
“ B. and S. ” ? or may a man, going out for the day, take three
biscuits and a dose of medicine after each, so as to get it all over
before he starts, for surely a biscuit is “food”? I think I have
seen some advice to our craft lately about our use of language, by
an eminent surgeon. Could not the Faculty also improve their
English? This puerile rendering of “post cibum” is on a level
with that of a tyro who should translate the good old London
Pharmacopoeia “ 1^. Opii contriti uncias tres,” “take of contrite
opium three ounces.”
March 6, 1897. Inquirer (84/5).
Sweating the Dispenser.
Sir, — I also consider your correspondent “Anti-Sweater” un¬
reasonable in his remarks about the work done in hospitals and
dispensaries. Holding, as I do, the post of dispenser in one of
these institutions, I must really protest against these exposures.
He may be relating what he actually saw, and his remarks may
apply to the work of most of us, but why not turn the blind optic
to our failings ? And why does he make our mouths water by
comparing us to the carpenter, the plumber, and the baker, when
these gentlemen draw at least double our wages (vide recent
advertisements in the Journal) ? Are we respected, or is our work
considered of any importance by the doctors, nurses, or porters ?
Why, the latter would scorn to exchange waistcoats with us, know¬
ing that if they did they would soon fall in the estimation of the
public. It is monstoous to insinuate that we as a body should
require a course of training either at Bloomsbury Square or any¬
where else to fit us for our work of doling out ointments in saucers,
mixtures in gin bottles, pills in paper, linseed meal in pillow-cases
and coal bags. Our ambition (Not. a bene : I am speaking for all of
264
PHARMACEUTICAL JOURNAL.
[March 20, 1897
us) is to partake sooner or later of that beautiful Benevolent Fund
of yours, towards which, by the way, we don’t contribute, before
we take our last sleeping draught. The Editor has my name
and address, but I am not at home to inquisitive people.
March 6, 1897. Blad R. O’Lard (84/13).
Sir,— In reply to “Dispenser’s” letter in the Journal, March 6, I
hardly think he can be in earnest when he invites me to give the
name of the institution referred to in my previous letter ; for
whilst we may say what we have seen, we may not always say
where we have seen it, for obvious reasons. As to the Inspector,
how often has “ Dispenser” had a visit from him in the fourteen
years he has been in the service ? In writing, I had no thought of
condemning the hundred and eighteen dispensers employed in the
Poor Law service, but those guardians who attach no more
responsibility to the dispensing of medicines than they do to the
distribution of stores, and expect a dispenser to do five hundred
bottles a day, this being at the rate of one bottle a minute for
eight and one-third hours daily. To fill, cork, and label any article
at such a rate is, I believe, impossible.
If “Dispenser” does three hundred and sixty prescriptions in
one day without proper assistance, I contend he does too much,
and unless he anticipates a premature end, should discontinue it.
In reply to his query if the dispenser mentioned in my letter was
a lady, Army man, or qualified chemist, he held none of these
qualifications. In the fifth annual report of the Local Government
Board, 1876, it states the position of dispenser in these institutions
is one of great importance. What has happened that they should
think differently twenty years later and open the appointment to
men with only the Army qualification ? I think it is much to be
regretted that any qualification short of that of a registered
chemist and druggist should fit a man for these appointments, and
hope those guardians who think so too will see to it.
March 9, 1897. Anti-Sweater (84/20).
The Proposed New Bye-Laws.
Sir, — I have read with interest the report of the Council meeting
and the discussion on the Preliminary and Minor examinations,
and am quite in accord with the line of thought and procedure. I
have all along thought that the Preliminary examination was too
easy and not in keeping with the noble position of a pharmacist,
and think the changes suggested more appropriate. No one should
grumble either at the advanced fee for the Minor, providing for
life-long registration as a chemist and druggist. There are
already too many chemists, but it must be remembered that
more than half of the drug stores of this country are not
registered, and the Society should have powers to do more
to close them. Then, again, as a member of a body of directors
known as the Sands-Cox Benevolent Sick Society, I got
a rule passed that all patients should get their advice from the
doctors in the area, the medicine to be dispensed by the qualified
chemists in the same area, but the public met in force with the
doctors to protest against this procedure, and were successful
in having this law rescinded, so that the members now
go to the doctors for their medicine as heretofore. It is
very discouraging to qualified men to find doctors do their own
dispensing, and to be hemmed in on all sides by unqualified quacks.
Again, would not qualified chemists subscribe to the Society and
take more interest in its affairs if they were allowed to act as
representatives on the Pharmaceutical Council ? I feel sure that
if more encouragement were given to Minor men in this way the
Society would get more support. It is of the greatest importance
that the Pharmaceutical Society and qualified chemists should be
more in sympathy, and in touch the one with the other.
Birmingham, March 6, 1897. Josiah Austin.
Sir, — The raising of the standard of the Preliminary examination,
I am sure, will meet with general approval ; in fact, it would ha ve
been a good thing had it been done several years back. The Minor
fee appears to offend a few, but there is no doubt it will raise the
standard of the trade and keep out those unfit to occupy such a
responsible position, and personally, I should like to see the £5 5s.
registration fee increased to £10 10.$. The Council is unable
to get Bills passed by reason of so many keeping out of the Society
after passing the Minor, and I would suggest that each new chemist
should become an associate, and by so joining together we should
be able to get numerous privileges which are at present utterly im¬
possible. This suggestion may be altogether impracticable, and
require a new Act of Parliament, if so, I should be glad to be put
right ; if not, to me it appears better than as at present proposed.
Plymouth, March 13, 1897. J. Arthur Buckley.
Sir,— I am pleased to see that the Council of the Pharmaceutical
Society is at length taking steps to raise the standard of education
required of those entering the chemist’s calling. In that respect
the new bye-laws certainly deserve cordial support, for I have
always considered that the modicum of education which enables a
youth to pass the present Preliminary is by no means sufficient to
fit him for his after career. With reference to the increase in the
fees for the Minor, the alteration appears to be necessary from the
point of view of the Society, and having regard to the perpetual
cost of maintaining the Register and enforcing the Pharmacy Act,
I fail to see that the total fees will form an exorbitant amount.
Uck, field, March 15, 1897. E. H. Farr.
Sir, — If the increased fee for the Minor examination is to be
understood as a charge for registration, as stated by the President
and others, how can a second fee of ten guineas, chargeable after-
twelve months from the failure to pass, be justified ? There should
not be two fees for one registration. Would it not be better to-
pass a bye-law making a separate charge for registration, payable
at the time of registration. Section 10 of the 1852 Act clearly
empowers the Council to do this. It reads, “Every such person,
who .... shall have obtained a certificate of qualification ....
shall be entitled to be registered .... upon payment of such a
fee or fees as shall be fixed by the bye-laws.” No one could reason¬
ably object to paying a fee for registration, and it would be much
more cheerfully paid after the examination is past than before it.
I would suggest this course as a matter of policy, as nothing
should be done which would cause young men to have an unfriendly
feeling towards the Society, either before their examinations or in
after life. If the first charge of ten guineas be adhered to, I would
urge that in cases of failure to pass the fee be three guineas on any
or each subsequent occasion, but it seems to me that it would be
better to keep the two charges distinct and have a fee for ex¬
amination, payable as at present, and a fee for registration,
payable at the time of registration.
Edinburgh, March 15, 1897. . . Claude F. Henry.
Sir, — Now that the Council of the Pharmaceutical Society has
boldly faced the question of the Preliminary examination and
increased the Minor fee, both of which, as you say in your current
issue, should certainly be regarded as matters of course, I would
strongly urge that attention should be turned to alteration in the
status of Minor men, on the lines which have already been fre¬
quently put forward in your columns. It is a complete anomaly
that men who have passed the examination which gives them their
qualification as chemists, should not be able to become “ Members”
of the Society. In my humble opinion, that, is one of the chief
reasons why the Pharmaceutical Society does not include the whole
of the craft. There is no doubt that the Minor (a complete
misnomer, by the way) is practically the examination, and the
Major is merely an excrescence which will in course of time die a
natural death. It is u ndeniably becoming less and less popular,
and it would be better if it were entirely abolished, the Minor being
divided into three or more stages as is done in the qualifying
medical examination. However, leaving this question for the-
present, my immediate point is, that Minor men who form the
great majority and backbone of the craft, ought to be members of
their own society, and not Associates merely — they will nob
feel that it is their own society until they become so.
March 13, 1897. “ Spero” (85/4).
*** Some of the suggestions offered in the correspondence on this subject could
not be carried into effect without fresh legislation, as explained at page 256.
Detailed reference will be made to this matter at an early date. — [Editor, P.J.i.
The Sale of Food and Drugs Act.
Sir, — That the Society of Public Analysts will soon be stigma¬
tised as a Society of Public Nuisances, if they continue to bring such
frivolous actions as many lately brought, goes without saying. Such
preparations as lime juice and glycerin are simply toilet articles, and
not properly speaking either food or drugs, and wrho was prejudiced
by arsenical soap sine arsenic. Honest men are brought to filthy
Police Courts on the most scandalous pretences to herd with pros¬
titutes, thieves, and brawlers of all sorts. Can we not as a body
protest against such annoyance with some chance of success ? It
would seem advisable that a committee should be formed for self-
March 20, 1897]
PHARMACEUTICAL JOURNAL.
265
protection, and to see that defensible cases are properly defended ;
one would not mind subscribing a reasonable sum annually for
such a purpose. The Sale of Food and Drugs Act is being abused
by ignorant J.P.’s and tricky inspectors for purposes for which it
was not intended. For instance, limes and glycerin was an inven¬
tion for purely decorative purposes, and has been sold as such for
many years, and is known to the trade and the public by that
name only. A defence on that ground alone would have saved the
gentleman convicted the other day. Again, the Food and Drugs Act
defines a drug as a medicine for internal or external use, therefore
when not required for medicinal purposes the same article ceases
to be a drug (vide the case in which beeswax sold by a grocer was
held not to be a drug, lately reported in Ph. J. ). The average
magisterial cranium is proof against a technical defence, but one
addressed to common (very common) sense may sometimes arrive
there. Perhaps a label declaring an article (not for medicinal use)
might be of some service. Goodness only knows what an Inspector
expects when asking for “ Lait Virginal,” for instance. Hoping
my suggestions may be of use to someone,
London, March 16, 1S97. E. Warrell.
The Proprietary Articles Trade Association.
Sir, — Your correspondent “Midlothian” has discounted the
value of his criticism on the above by his modesty in withholding
his name. If he had given that we might have been better able to
tell whether he was a gentleman who had personal acquaintance
with the subject whereof he wrote, or whether he was merely
stating what he conceived to be the state of things in general,
from observation of his corner of the isle in particular. I will now
try to give him a little additional information. He was nearly
correct when he supposed I meant that “ the average chemist has
a number of preparations of his own, representing so many adver¬
tised nostrums, and that he is able to sell his own when another is
asked for, to the extent of 20 per cent, of all orders for that pro¬
prietary article.” Correction : The said “ own preparations ” need
not necessarily represent, or be imitations of, the nostrums, so long
as thej' are as good as, or better than, the latter for their specific
purpose. “Midlothian ” denies that those composing the bulk of
the craft are a herd of imitators.” So do I. “ Herd ” is a word
usually applied to oxen and swine, and pharmacists are neither.
For present purposes the members of the craft may be divided
into two classes : — (a) Those whose life has been principally passed
in “ the good old times,” and who have never altered their business
methods. ( b ) Those who have been brought up with an enviro-
ment of cutting and struggle. Some of the former have been able
to afford the luxury of business conservatism (probably “Mid¬
lothian” is one of them) ; some have not, and in consequence have
either succumbed or are moribund. The vast majority in the
second group (b) have adapted their system of business to their
new surroundings by meeting the competition in the sale of pro¬
prietaries, and by running a number of specialties of their own.
They have acted on the maxim — “Make as much show of cutting as
you can, and do as little of it as you can.” In the nature of things,
group (a) must be an ever-lessening quantity, and group (b) an
ever-increasing one. Those in the latter group push their own
things on every available occasion (P.A.T.A. goods excepted) ; in
other words, they substitute. Parenthetically, I might here define
substitution, in the sense in which I am using it, as “counter¬
recommendation, or the art of inducing your customer to buy what
you would like him to take in lieu of what he thought he would
like, without attempting to deceive him.” It is as unlike fraudu¬
lent imitation as a “ Welsh rabbit ” is to its four-footed namesake.
With regard to the extent to which it is practised, I will not pretend
to speak for the “ Midlothian ” region, but I assure him that I know,
from personal inquiries and observation, that the custom is widely
prevalent in the large towns of England. I believe almost any of
the commercial travellers or editors of trade journals will corrobo¬
rate this. Statistics published in the Pharmaceutical Journal (in
1890, I think) show that such was the case then, and there is cer¬
tainly more rather than less now. “Twenty per cent.” is, I
believe, a fair estimate of the number of successful “pushes”
accomplished by the “average chemist,” though some put it at a
higher figure. In the case of a man of gumption and tact it need
not be less than 25 per cent, all round. The proprietor of Carter’s
pills has stated that forty people out of every hundred who ask
-for that medicine get persuaded to have the dealer’s own. Up-to-date
•chemists and store-assistants appear to be about equally proficient
in the “gentle art” — though probably the latter would bear the
palm. Finally, I shall always maintain that if an advertiser will
not protect the price of his article when he can now so easily do so,
the retailer is justified in ousting that article whenever he can, in
any way or by any wile consistent with honour and integrity.
London, March 6, 1897. William Johnston.
Sir, — In your splendid issue of February 27 the case for and the
case against this Association was stated ; in my humble opinion
the latter squashed the former. However, be that as it may, I am
opposed to the P.A.T.A. principally on three grounds : (1) It does
not serve the object for which it exists ; (2) it increases the sale of
quack remedies — a thing not to be desired ; (3) it affects individual
freedom of action to a malevolent extent. In proof of these state¬
ments I may say: (1) A chemist who “cuts” has no difficulty
whatever in buying what he wants from a friendly brother chemist,
the stricture of the “black list ” not affecting him ; it only touches
about twenty houses, and all of them, or nearly all, are “ stores” ;
(2) “patent” medicines never heard of before are now getting a
cheap advertisement through this mushroom Association ; when
customers ask me about these quack remedies I say I can’t recom¬
mend them, and thus discourage their sale as much as possible ;
(3) I can’t do better than say, with Dr. Macnaughton- Jones in his
recent address, that “the whole tendency of modern thought,
despite trades unionism and caucuses, is in the direction of
individual freedom of action. The liberty to do what is right must
ultimately prevail, no matter how vigorous the attempt to curtail
and imperil the right of such independent action.” Mr. Glyn-
Jones, the energetic Secretary of the P.A.T.A. , has done his best,
but I am afraid he only “ beats the air.” Quite true many chemists
•in England have taken kindly to the movement, but the quiet
chemist-cutter has been going on as usual, not hindered by any.
I am surprised at the mild criticism hitherto offered, but perhaps
the indefatigable Secretary will yet get his eyes opened and see
the futility and abortiveness of his efforts.
March 9, 1897. “ Catalysis ” (SI/24).
Solubility of Iodine in Cod-liver Oil.
Sir, — I am afraid that in my desire for brevity I put my query
in such general terms that I did not make my difficulty plain.
Both the gentlemen who came to my assistance seem to think that
I wish to preserve the brown colour of the solution. It is not the
disappearance of the colour, but its unexpected and apparently
capricious reappearance that troubles me. The oil is intended for
internal use, and the doctor tells me that he has found, though not
in my dispensing, the reappearance of the colour, followed by dis¬
tressing symptoms in the patient — burning sensations, nausea, and
loss of appetite. I avoided this danger by warning the nurses not
to give any oil that had darkened, but to return it to me at once.
I have had three bottles out of about twenty brought back in this
way. The difference can hardly have been in the oil, as all the
bottles were from the same cask. I dissolved the iodine in pure
ether and divided the solution between the four or five bottles I
had to prepare each day. The variation may have been caused by
the difficulty of dividing the ether solution with perfect accuracy.
What I want to know is whether the combination of iodine and cod-
liver oil is a stable one, and whether pushing the iodine to the
limit of absorption, Y\ gr. to the fluid ounce, lessens the stability
and makes it more liable to separate. I find no difficulty if I put
a little under the full quantity. I have told the doctor that I
cannot undertake to give the full Y gr. at present, and he is satis¬
fied with the smaller dose, but I should like to know whether it is
possible to keep the full quantity in ■ combination. I shall do my
best to find this out by experiment, but if anyone else has succeeded
in doing so it would be encouraging to hear of it.
Ventnor, March 7th, 1897. M. Gibson.
Ungues tum Hydrargyri Nitratis.
Sir, — Briefly stated, the questions at issue between Mr. Squire
and myself are these. Does the process suggested by him produce
a more acid ointment than the B.P. process, and if it does, is it an
improvement? As to the former, any pharmacist may satisfy
himself by actual experiment that it does produce a more acid
ointment ; and as to the latter, every pharmacist will have his own
opinion. My opinion is that the more acid ointment is not an
improvement, and hence I consider that the adoption of the pro¬
cess recommended by Mr. Squire, namely, to add part of the acid
at a high temperature and thereafter at a lower temperature the
solution of mercuric nitrate, would be a decided mistake.
Hawick, March 16, 1897. • Thos. Maben.
266
PHARMACEUTICAL JOURNAL.
[Mabch 20, 1897.
ANSWERS TO QUERIES.
Recipe fob Emulsion. — We shall be pleased to assist you if you
will send your name. [ Reply to A. T. J. — 85/1.]
Via vi Capsules and Tablets.— The preparations you name are
to be obtained from the British Viavi Company, Oxford Street, W.
[ Reply to Medical. — 82/40.]
Tesla Coil. — (1) Glass may be used instead of vulcanite. (2)
375 is quite near enough to the statement “ about 400 ” to be right.
(3) About a five-inch spark. [ Reply to J. P.N. — 83/22.]
Cheap Saline. — The following will give you approximately the
article you require : — Sodium bicarbonate, 40 ounces ; tartaric acid,
35 ounces ; sugar, 25 ounces. [ Reply to C. T. I). — 83/39.]
Minor Examination. — You must have attained the full age of
twenty-one years on or before the fifteenth day of the month
immediately preceding that in which the Boards of Examiners
meet, and they meet in January, April, July, and October.
[Reply to J. A. C. — 85/12.]
Specific Volumes. — We know of no work treating solely of
specific volumes. You will find a good article on the subject in the
last edition of Watts’ ‘ Dictionary 5 (Morley and Muir), vol. iv.
The practical specific volume of acetic aldehyde is 56 -6, .as deter¬
mined by Ramsay. [ Reply to Major. — 82/45.]
Decoloration of Tincture of Iodine. — According to Hager, the
solution contains tri ethyl-ammonium iodide, which decomposes
in course of time into triethylamine and ethyl iodide, with sodium
iodide. Remington states that, on prolonged standing, a crystalline
precipitate of sodium tetrathionate sometimes forms in the liquid.
{Reply to C. T. J.— 84 7.]
Label Paste for Gold Paper Labels. — Best glue, 2 parts ;
gum acacia, 2 parts ; simple syrup, 1 part ; water, q.s. Cover the
glue with water and let it soak twenty-four hours. Then dissolve
with gentle heat, add the gum acacia and the syrup and about 6
parts of water. If necessary, add more water when cold. When dry
coat with good white copal varnish. [ Reply to Countryman. — 83/23. ]
Books for the Minor Examination. — Attfield’s ‘Chemistry’
(Gurney and Jackson) ; Muter’s ‘ Analytical Chemistry ’ (Simpkin) ;
Green’s ‘ Botany,’ Vol. I. (Churchill) ; and Southall’s ‘ Materia
Medica ’ (Churchill) should suffice, in addition to the books you
have. Cross and Cole’s ‘ Modern Microscopy ’ (Bailliere) gives the
instructions you require about mounting microscopical objects.
[Reply to C. T. J. — 84/7-]
Hair Curling Fluid. — Borax, 3 ounces ; carbonate of potash,
2 drachms ; gum acacia, 1 drachm ; spirit of camphor, 1J fluid
ounces ; spirit of rosemary, 1^ fluid ounce ; hot water, 40 fluid
ounces. Dissolve the solids in the water. When cool add the
spirit. On retiring at night wet the hair with this and arrange
loosely, or roll in paper as usual while wet with the liquid.
[Reply to Semper Idem. — 84/6].
Hair Wash with Bay Rum and Yolk of Egg. — If you use good
bay rum as the menstruum with the yolk of egg, you need not
fear decomposition, as the alcohol present will prevent it.
A little glycerin of boric acid added as well will further ensure the
preservation of the liquid. The egg yolk should be rubbed down
first perfectly smooth with the glycerin of boric acid, then a little
rose water added, and lastly as much bay rum as the price of the
article will permit. The egg will separate, so you must label the
bottle “ To be shaken.” [Reply to K. — 84/14.]
Measurement of High Temperature. — Yes, the expansion pro¬
ceeds regularly, but at such a high temperature as you refer to
the copper would probably be attacked by the air. You must use
a porcelain air thermometer or a platinum resistance thermometer.
In an arrangement described in the Comptes rendus, xcvii., 1053, a
current of cold Avater is allowed to pass through a spiral copper
tube placed in the furnace, and so regulated that each rise of ten
degrees in the temperature of the water corresponds to a thousand
degrees in that of the furnace. [Reply to H. S. B. — 83,25.]
Fireproof Paint.- — There are many formulas and patents for
this. One which is stated to give good results is finely powdered
glass 20, finely powdered porcelain 20, any stone in fine powder 20,
quicklime 10, sodium silicate 30, or sufficient to make a workable
mass. It may then be mixed with any pigment, such as ochre or
any other tint. All the ingredients must be in the finest possible
powder. Two coats should be applied, the second about six hours
after the first. Several patent paints are made with asbestos,
which is ground in water and then mixed with potassium or sodium
silicate. [Reply to Semper Idem. — 84/6.] ■
One-Solution Intensifier. — A good one-solution intensifier
can be made by mixing copper sulphate, 100 grs. ; potassium
bromide, 100 grs. ; distilled Avater, 10 ounces. “ Directions for-
use : — Immerse the negative in this till bleached, wash and re¬
develop with hydroquinone or metol. This solution may be used
as a reducer by merely allowing the negative to be superficially
bleached and then washing and refixing.” You would find this
preparation much preferable to any uranium intensifier and*
much cheaper than platinum, besides being likely to attract
amateurs, as it can be used both for reduction and intensification,
[Reply to Anglo-Hibernian. — 83/26.]
Fireproofing Timber. — One of the simplest methods is to
saturate the timber with solution of tungstate of soda ; if this is-
done in a vacuum chamber, by means of which the Avood is partly
deprived of the air contained in its cells, a very satisfactory result
will be obtained. Payne’s process consists in treating wood under
these conditions first with solution of sulphate of iron, and then,
Avith chloride of calcium ; calcium sulphate is thus precipitated in
the tissues of the timber, which is rendered incombustible and
much more durable. There are several other methods besides these,
phosphate of ammonia and tungstates being most useful. A coat
of common whitewash is an excellent means of lessening the com¬
bustibility of soft wood. [Reply to Semper Idem. — 84/6.]
Ginger Beer. — The following will give you a very good brew : — -
Sugar, 6ozs. ; bruised ginger, ljoz. ; cream of tartar, 3 ozs. ; one lemon
sliced; boiling water, 1J gallon. Pour the water on the ingredients,
and infuse for two hours, then strain. When the temperature of the
liquid has fallen to 100° F. , add a few pieces of compressed yeast,
and let it stand to ferment for twenty-four hours in a warm place,
then bottle off'. You may, if you like, aerate the above infusion-
in an ordinary soda-water machine without fermenting, or may
make a bright ginger syrup Avith soluble essence of ginger and a
little lemon, and aerate this after svruping in the ordinary way,
but the aerated ginger beer is not nearly so palatable as the old-
fashioned fermented “ginger pop.” Of course a much more
palatable preparation can be produced by using larger quantities
of sugar than given above, but then the alcohol produced will be
in excess of what is permitted by the Excise in the case of beverages
sold without a licence. [Reply to J. B. M. — 83/36.]
OBITUARY.
Stocker. — On March 9, George Stocker, aged 11, son of Mr,
George Stocker, chemist and druggist, Exeter. The circumstances
attending the death of the boy are peculiarly sad. Whilfr
standing engaged in conversation with a companion a large
St. Bernard dog collided with him, and he fell, striking his head
with considerable force, rendering him unconscious for a few
minutes. He walked home and went to bed, where he remained-
conscious for some time, but about five hours after the accident he
lost consciousness and, notwithstanding medical aid, died. His skull
had been fractured, and there was an effusion of blood on the braim.
Much sympathy is felt for Mr. and Mrs. Stocker and family.
Pratt. — On January 28, Josiah Pratt, Chemist and Druggist^.
Wolverhampton. Aged 69.
Taylor. — On February 17, John Taylor, Chemist and Druggist,
late of Ipswich. Aged 72.
Payne. — On March 8, William Henry Payne, Chemist and Drug*
gist, Ashton-under-Lyne. Aged 73.
Ryder. — On March 10, Thomas Frederick Ryder, Chemist and
Druggist, Manchester. Aged 65.
COMMUNICATIONS, LETTERS, etc., have been received from
Messrs. Blythe, Chambers, Christy, Coltart, Dearden, Farr, Hayles, Henry, Hill,
Howie, Jackson, Jesper, Jones, Kenney, Lake, Line, Lunan, Maben, MacEwan,
McFadden, Morris, Peck, Philip, Richardson, Robins, Shaw, Speedie, Summers,
Thompson, Warrell, Wilmer.
Mabch 27, 1897.]
PHARMACEUTICAL JOURNAL.
267
THE ANTIQUITY AND HISTORY OF THE MORTAR.
BY C. J. S. THOMPSON.
The mortar is the most ancient of pharmaceutical implements,
its earliest use carrying us back to prehistoric times, when the
early Briton bruised his grain in the hollow of a granite boulder.
There is little doubt indeed that mortars were employed for the
purpose of - bruising and reducing hard bodies to powder, centuries
before medicine as an art was thought of or known.
The name is derived from the Latin word mortarium, which is
probably from the root mordeo, to bite, akin to the Sanscrit mrid,
to grind or to pound ; the literal meaning of the word being a
vessel in which substances may be pounded with a pestle.
The origin of the mortar appears to have been identical with
that of the mill or quern, as it was called in ancient times.
The primitive implement used by prehistoric nations for
the purpose of crushing their grain, was simply made by hollow¬
ing out a cup-shaped hole in a block of stone or granite, and
pounding the grain placed in this receptacle with a smaller stone
of suitable form. These grain-crushers composed of stone,
together with stone rollers and pounders, have been found in the
circular huts of the Britons in several parts of North Wales.
This method was also used by the early J ews before the Christian
era for crushing their spices and gums, the knowledge of which
they doubtless gathered from the Egyptians during the captivity.
In many of the ancient Egyptian papyri we find directions given
to bruise certain herbs and roots, although no mention is made
of the implement used for that purpose, but we
have proof that mortars were employed by the
Egyptians from many ancient carvings of stone
still extant. It is interesting to note that the
mortar has also been known to several Oriental
and savage races from time immemorial, and in
the mortar employed by the pharmacist to-day
we have an implement that links us, not only
with prehistoric man, but also with the savage
races of the world. In Africa, mortars and
pestles of wood have been used from a period of
unknown antiquity for the purpose of crashing
grain. The one illustrated in Fig. 1 is composed of wood, and
was brought from Central Africa. In India, stone mortars with
wooden pestles have for centuries been
used for shelling and pounding rice.
Fig. 2 represents a Cingalese mortar of
stone, from 2 to 3 feet in height, taken
from a drawing of the seventeenth cen¬
tury. Coming to the time of the Roman
Empire, we have the first real evidence of
the use of the mortar for pharmaceutical
purposes. Medicine and pharmacy allied,
in the time of Celsus, had become practi¬
cal arts, and we know from the prepara¬
tions described by that author that prac¬
tical appliances were necessary. Thus the malagma used as an
application to the skin was a kind of soft mass directed to be
beaten up to the consistency of a thick paste, and the ingredients
of the catapotia were often ordered to be bruised before being
mixed.
Roman mortaria composed of earthenware are very commonly
found, and many examples may be seen in most of our museums,
among other Roman remains. They were chiefly made for
culinary use, and although they vary very little in pattern, the
sizes are numerous. The larger ones were, as a rule, very strongly
made, and all had a thick divided rim with a rounded moulding.
Vol. LYHI. (Fourth Series, Yol. IY.). No. 1396.
Fig. 2.
The inside was roughened with splinters of flint, or hard stone, or
hard burnt earthenware, which was fixed on with a kind of
“ slip” or liquid clay, with which the Romans finished their ware.
A wooden pestle was used
with these mortaria, which
were, no doubt, chiefly em¬
ployed for triturating and
mixing various condiments
for domestic use. The
Roman mortarium shown in
Fig. 3 is 28 inches in
breadth, and bears the
stamp of the maker’s name, showing it to be the work of one
Publius Raso.
Some of the smaller mortaria found are composed of a very white
clay of a vitreous character, burnt hard like porcelain, and are
non-absorbent. These were probably used for mixing more deli¬
cate condiments. There were large manufactories for mortaria in
Britain, situated chiefly in the South of England at the mouth of
the Thames, and in Essex and Staffordshire. From these factories
there was a considerable export trade to Rome and Gaul.
Roman mortars of stone are much rarer, and the one depicted in
Fig. 4 is a unique specimen. It was with little doubt at one time
used for pharmaceutical purposes. Composed of stone, with a
solid square base, it stands about 12
inches high, and is about 8 inches
broad. The notches at the corners are
evidently intended for fixing it down
on a wooden table or slab to keep it
steady when being used for pounding
or breaking up hard substances. Closely
akin to mortars were the querns or
small mills, used for grinding purposes
from the Roman period. In shape they
somewhat resembled the mortar, but
were covered in at the top, having a hole in the centre through which
the pestle was worked. They were
made of stone and wood. .A beautiful
example of a wooden quern, depicted
in Fig. 5, is now in the possession of Mr.
E. W. Cox, to whom I am indebted for
the sketch and other particulars. It
stands 13 inches high, and is made of
very hard wood. It is an exquisite
specimen of the turner’s art, some of
the side mouldings being of great
delicacy, no thicker than a fine needle,
yet are perfectly true in every par¬
ticular. The pestle was worked through
the hole in the centre of cover. These
wooden querns were used during the
sixteenth and seventeenth centuries.
There is little doubt that marble succeeded stone as a material
for making mortars, and this brings us down to mediaeval times
when the apothecaries, combining the practice of medicine and
pharmacy, became wielders of the pestle.
The value of the mortar as a pharmaceutical implement was
recognised by these early practitioners, and was given the most
prominent position in their shops, and so the pestle and mortar
became a symbol or trade sign of pharmacy.
The great bell-shaped mortar, which was of considerable
capacity, usually stood mounted on a solid block of wood neai the
centre of the shop, the huge pestle, 3 feet or more in length,
268
PHARMACEUTICAL JOURNAL.
[Mabch 27, 1897
being suspended from a long wooden spring beam by a chain and
ring. One can readily picture the youthful
apprentice, clad in jerkin and trunk hose,
exercising his muscles with the ponderous
pestle, and with what mingled feelings he
would essay the task of pounding half a
hundredweight of aloes to begin his day’s
work and give him an appetite for his midday
meal. These large mortars were usually
bell-shaped in form, as illustrated in Fig. 6,
and composed of iron or bell metal. The
smaller mortars of this period were made of
brass, copper, or
bellmetal, and were
occasionally orna¬
mented with some
symbol or device.
They were often
elegant in form,
and usually stood
in bright array on
the shop counter.
Fig. 6. The pestles had
flat tops and double ends, so that either end could be used for
pounding.
The bell metal mortar, depicted in Fig. 7, dates from the time of
Oliver Cromwell, and bears the arms of the Commonwealth on
its side. It was probably once the
property of an official State apothe¬
cary. The brass mortar shown in
Fig. 8 is peculiar in shape, and is
supported by four short legs. It
dates from the early part of the
seventeenth century, and round
the middle are inscribed the letters
of the alphabet. Fig. 9 represents
a particularly handsome example
of the brass mortar of the seventeenth century. Copper mortars
when polished have a very elegant appearance, and are somewhat
rare. One specimen in possession of the writer is depicted in
Fig. 10. A very fine bell-shaped mortar of brass was found in
Chester about two years ago, and is now deposited in the museum
of that citjr. It stands nearly two feet high, and dates from the
early part of the eighteenth century.
Small brass mortars were also formerly much used by house¬
wives in the stillroom, for various domestic purposes, and may
Fig. 9. Fig. 10.
often yet be found ornamenting the kitchen mantel-shelf in old
country houses.
During the last and the early part of this century Italian marble
was largely employed for making mortars, but with the intro¬
duction of Wedgewood and composition ware, which is lighter,
more durable, and less liable to be acted on by chemicals,
marble mortars have now almost gone out of use with phar¬
macists. Small antique mortars of bronze are still to be found
in many French pharmacies, often bearing some symbol or device,
such as St. Michael and the dragon. They are generally much
prized by their possessors.
LEGAL HINTS FOR PHARMACISTS.
Stills.
The use or even the possession of a still in the United Kingdom
is illegal, unless the person keeping or using is licensed to do so.
The duty is 10s. per annum, and the licence expires on July 5.
It is transferable to a succeeding owner or user, and the penalty for
unlawfully keeping or using is £50. In cases where a person first
becomes liable to duty subsequent to October 10 in any year, a
proportion only of the duty is levied. Thus, a person setting up a
still on any day between J uly 5 and October 10, would have to
pay the full duty ; if the commencement be between October
Hand January 5 following, a payment of 7s. 6 d. would suffice,
and so on in a like ratio.
Exemptions are made in favour of what the Board terms
“ Professional Chemists,” but this does not necessarily mean
persons who are registered under the Pharmacy Acts. The designa¬
tion is in fact used to indicate persons engaged in teaching chemistry,
or carrying on analytical investigations, and the nature of whose work
does not give rise to any suspicion of the manufacture for sale of
spirituous articles. Any person, however, who desires to carry out
experiments involving the use of a still or retort, or who wishes
to employ, for manufacturing non-spirituous articles, apparatus
coming within the official conception of a still, may obtain exemp¬
tion from duty by applying to the Board through the excise officer
of his district. The general idea upon which the Board acts in
granting these concessions seems to be that no objection exists to
distillation apparatus which cannot be used or made efficient for
the manufacture of spirit or spirituous mixtures. Thus makers of
coal gas need not take out a licence in respect of their retorts, nor
is the distillation of tar and tar products interfered with.
It may be well to add, with reference to exemptions, that
though a person may be keeping or using a still or retort for per¬
fectly bona-fide scientific purposes — in fact, for purposes which the
Board would have no hesitation in sanctioning — yet if that person
omits first to obtain official permission to keep and use the
apparatus, he will be regarded as an offender and treated accord¬
ingly until he either obtains a licence or the Board’s leave to act
without one. The Board has secured convictions against persons
who have elected to consider that the application for permission to
use a still is merely an unnecessary piece of formality.
Definition. — The precise interpretation put upon the word
u Still ” by the authorities is not clearly known, but from the
foregoing considerations it may be assumed that, strictissime, it
covers everything capable of being used or fitted for use in the
conversion of a liquid to its gaseous form. It has been urged that
glass tubing and the domestic kettle might be made to come
within the description, and perhaps there may be some logic in the
argument, but at any rate the authorities have not shown any
disposition to stretch the interpretation to such a point. The
exhibition of glass retorts in the window of a shop where chemical
apparatus was sold has, however, been known to provoke a visit
from a Revenue officer.
Entry. — The premises of a licencee may be entered by an Excise
officer at any time, but if at night, i. e. , between 11 p.m. and
5 a.m., the entry must be made in the presence of a constable.
A still must not be removed from one portion of a licencee’s
premises to another without notice duly given to the Board, and
of course the same prohibition applies to removal off the premises.
Thus it practically obtains that no person can cease to keep or use
a still without notice.
A still licence may be suspended or revoked if the licencee be
convicted of any offence against the Spirits Act, but actual cases
of this are very rare.
In Scotland. — No still may be of a greater capacity than fifty
gallons, unless special permission be obtained from the Board.
Note.— These observations are not applicable to licensed distillers,
rectifiers, and vinegar makers.
Fig. 7.
Fig. 8.
MABCH 27, 1897]
PHARMACEUTICAL JOURNAL.
269
PRACTICAL PHARMACOGRAPHY.
ARM0RACIA2 RADIX.
Horse Radish. — Fr. Raifort. — Ger. Meerrettig.
Macroscopic Characters. — The root of Cochlcaria armor acia is
used in the fresh state, its average length being about 20 Cm. , and
Fig'. I. — A rmo raci^e Radix. — One-fourth natural size,
its diameter 2 to 2| Cm. It is cylindrical, somewhat flexible, and
externally whitish or, on drying, pale brown. There are very few
branches to the root, and it is marked with a few transverse scars.
When bruised and wetted it gives off a pun¬
gent odour, whilst it has a burning taste and
a flavour resembling that of mustard.
Microscopic Characters. — A transverse
section of the root shows a central column
or stele, consisting of parenchyma loaded
with small starch granules, but with minute
vascular bundles scattered over its surface,
and more crowded near the cambium ring. In
the upper portion, or rootstock, these bundles
formaringof wedges just inside the root-bark.
ANTHEMIDIS FLORES.
Chamomile Flowers.— Fr. Camomille Romaine.— Ger. Romische
Kamillen.
Macroscopic Characters.— The flower-heads of Anthemis nobilis
may occur in commerce in three forms— double, semi-double, and
single or Scotch chamomiles— but the last-named are seldom met
with. Double chamomiles, which are chiefly imported from Saxony,
France, and Belgium, consist of a large number of ligulate florets
surrounded by a ring of membranous bracts or phyllaries. Inthesemi-
A B
FI F F2 E
Fig'. III. — Anthemidis Flores. — A, double flower head; B, single do., cut verti¬
cally through middle ; C, D, flower heads of Matricaria chamomilla, cut vertically
through thalamus ; E, central floret of chamomile, with palea ; F, ray floret of
ditto, with phyllaries, FI and F2. (A, B, C, D, natural size ; B, F, enlarged.)
double variety, which are mostly grown in this country and usually
known as “single” chamomiles, a few of the central florets
remain tubular, whilst in the Scotch chamomiles, which alone are
properly termed “single,” there is only a single outer row of
white ligulate florets, the central ones being tubular and yellow.
On carefully removing the florets from any of the three varieties,
the central portion of the flower-head is seen to be covered with a
number of chaffy scales (palese) or membranous bracts, one of these
occurring at the base of^each floret. If the flower-head be cut
vertically through the middle, it will be seen that these palese
stand on a solid, conical thalamus or receptacle. The limb of the
calyx is not developed in the florets, the ovary, therefore, not being
crowned with pappus, but the tube of the calyx adheres to the ovary.
The flower-head of the German chamomile, Matricaria chamo¬
milla, somewhat resembles that of the single Roman chamomile, but
in the former the receptacle is hollow and there are no palese, so
that when the florets are removed the conical, hollow receptacle is
left bare. The double flowers of Pyrethrum parthenium, again,
have a nearly flat receptacle and no palese.
Microscopic Characters.— The surface of the tubular corolla
presents pluri- cellular glands which, when viewed from above,
appear oval in shape, with a dark centre ; viewed sideways
they appear to contain about six cells with a sac-like cavity above
them. The cells of the upper part of the tubular florets are
papillose.
ARNICA RHIZOMA.
Arnica Rhizome. — Fr. Rhizome d’Arnica. — Ger. Wohlverleiwurzel.
Macroscopic Characters. — The rhizome of Arnica montana is
collected in spring or autumn, and occurs in commerce in slender
Fig. IV.— Arnica Rhizoma. — A, natural size ; B, transverse section (enlarged),
pieces about 5 to 10 Cm. in length, and about 3 to 5 Mm. thick.
It is often crowned with the remains of greyish-green, finely
wrinkled leaves, and bears on its under surface scattered, wiry
5 4 3 2 1
Fig. V. — Arnica Rhizoma. — Transverse section (x abt. 60), showing (1) outer
bark (2) inner bark, (3) oil-ducts, (4) woody bundles, and (5) pith. (After Berg.)
rootlets, 6 to 8 Cm. long. At intervals of about 6 Cm. the rhizome
sometimes gives off branches which give it a jointed appearance.
The outer surface is dark brown, and on the upper side are found
the scars left by fallen leaves.
Microscopic Characters. — A transverse section of the rhizome
shows a moderately thick whitish-grey bark, the inner part of
which contains a ring of oil-ducts. The woody portion of the
8 7 6
Fig. VI.— Arnica Rhizoma.— Longitudinal section (x abt. 120), showing (6)
vessels, (7) oil-duct, (8) starchy parenchyma. (After Berg.)
rhizome consists of light yellow wedge-shaped bundles, separated
by broad white medullary rays, and enclosing a whitish pith. In the
rootlets the bark is white internally and also contains oil-ducts.
Fig. II. — Armoracue
Radix. — Transverse
section (natural size).
270
PHARMACEUTICAL JOURNAL.
[Mabch 27, 1897
BOTANIC GARDENS OF THE WORLD.
VI.— KEW GARDENS (continued).
Peter Good, a Kew gardener, in 1796 was sent to Calcutta to
bring home Smith’s collection. In 1801 he was appointed assistant
to Robert Brown, the botanist attached to Flinder’s voyage of
survey of the coast of Australia. Through him Kew derived its
fine collection of Proteacece. Good and Brown made large
collections at King George’s Sound and surveyed the whole south
coast of New Holland. Good died of fever at Sydney, June, 1803,
but his collection of seeds was forwarded to Kew.
The next special collector was George Caley, who was sent out by
Banks in 1801 to collect plants for Kew in New South Wales. He
lived for about ten years in the colony and sent home a number of
plants, e.g., Livistona, australis, one of the most notable ornaments
of the Palm House till it was taken down in 1876. From 1816 to
1822 he was Superintendent of the Botanical Gardens at St. Vincent.
He died at Bayswater, 1829,
In 1803 another Kew gardener, William Ker, was sent out to
collect in China. He introduced Lilium tigrinum and Lilium
japonicum. The well-known flowering shrub, Kerria japonica ,
perpetuates his name. After visiting Java and the Philippines, be
became Superintendent of the Royal Botanic Garden, Ceylon, 1812,
and during the course of the next year visited Adam’s Peak, on
which he discovered many new plants. He died in Ceylon, 1814.
Alexander Moon, a collector for Kew at Gibraltar and on the
Barbary Coast, succeeded Ker as Superintendent at Ceylon, and
sent plants to Kew from that island. He died in 1825.
Allan Cunningham, appointed botanical collector to Kew by
Banks in 1814, spent two years in Brazil with James Bowie, who
had entered the garden in 1810. In 1817 Cunningham enriched Kew
with bulbs and succulents from the Cape of Good Hope. In the
Orange River States he discovered the beautiful Amaryllidaceous
plant, Imantophyllum Aitoni. Early in 1817 he joined Oxley’s
Australian Expedition for exploring the Lachlan and Macquarie
Rivers, and subsequently was attached to Captain King’s expedition
for surveying the coast of Australia. He visited various parts of
the east and west coasts of that continent, and also Tasmania,
New Zealand, and Norfolk Island, making everywhere extensive
collections. Among the new plants introduced by him were
Araucaria Cunninghamii, Laportea gigas, and Archontophcenix
Gunninghamii. In 1836 he became Superintendent of the Sydney
Botanic Gardens and died three years later, leaving his numerous
manuscripts and private herbarium to Kew.
David Lockhart, a gardener at Kew, sailed in February, 1816, as
assistant to Christian Smith the botanist, in Captain Tuckey’s
ill-fated expedition to the Congo. He sent to the gardens a
number of plants, e.g., Gardenia longiflora, and in 1818 was
appointed Superintendent of the Botanic Gardens, Trinidad, where
he died in 1845. “ Between the years 1823 and 1825 a considerable
number of species of orchids were received from Trinidad, for¬
warded by Mr. Daniel Lockhart, the Superintendent of the Gardens,
among which were the first plants of Stanhopea insignis, Oncidium
papilio, Lockliartea, elegans, Catasetum tridentatnm, Ionopsis pallidi-
dora, and others, all of which were epiphytal, and many of them
being sent growing on portions of branches as cut from the trees,
which being accompanied by instructions from Mr. Lockhart as to
how they should be treated, led to the successful cultivation of
epiphytal orchids. The interesting aquatic, Pontederia crassipes ,
was introduced at Kew by Lockhart from Trinidad.
L’heretier de Brutelle, a French botanist of some reputation,
came to England in 1786, and made a study of the Kew collections
which he subsequently utilised in his “Sertum Anglicum, sen plant ae
rariones, quae in hortis juxta Londinum imprimis in horto regio
Kewensis excoluntur.” The plates, of which there were thirty-four,
were the work of Redoute, the celebrated French botanical artist.
L’heretier speaks in warm terms of the resources of the gardens,
and describes many of Masson’s introductions.
William Cobbett for a time (about 1773) was employed as a
gardener at Kew, and attracted the notice of William IV. while
he was sweeping the grass plot round the foot of the pagoda.
A more noted work than that of L’heretier was the ‘Delineations
of Exotic Plants cultivated in the Royal Gardens at Kew,’ drawn
by Francis Bauer. Published in 1796, it contains an interesting
Preface by the younger Aiton. Bauer was an Austrian who came
to England in 1788 and was attached as draughtsman to Kew
Gardens by Banks. From Aiton’s Preface we learn that the
Directors of the East India and the Sierra Leone Companies as
well as the Government of Jamaica sent presents of plants to Kew.
Bauer worked for fifty years at the gardens. “ In the delineation
of plants he united the accuracy of a profound naturalist with the
skill of the accomplished artist. . . In microscopical drawing he
was altogether unrivalled, and science will be ever indebted for his
elaborate illustrations of animal and vegetable structures of which
invaluable specimens are preserved in the British Museum and in
the University of Gottingen.” Niepce, the original discoverer of
what is called the Daguerreotype, resided about the year 1827 in
Kew, and induced Mr. Bauer to submit his discoveries to the Royal
Society.
William Townsend Aiton succeeded his father in the superintend¬
ence of Kew Gardens in 1799. Ten years later with the assistance
of Dr. Dryander, librarian to Sir Joseph Banks, he published a
second edition of his father’s works in five volumes, and in 1814
issued a Catalogue or Epitome of the species contained in the five
volumes for the use of practical gardeners. In 1822 Mr. Aiton
began an important undertaking. He commissioned drawings to
be made of the new and unfigured plants in the garden. The first
artist he engaged was Thomas Daucauson (a young gardener from
the Royal Botanic Garden at Edinburgh), who had a talent for
drawing plants. Aiton finding that he was “ qualified to draw the
plants sufficiently accurately for him to be identified, in time he
was entirely occupied in drawing, which he continued to do till the
summer of 1826, when he unfortunately became insane. . . He
was succeeded by George Bond, then a young gardener at Kew, who
was employed in drawing for nine years, when in 1835 he became
gardener to the Earl of Powis at Walcot. . . The number of
subjects drawn by these two artists amount to about two thousand,
of which about seventeen hundred were drawn by Mr. Bond. On
Mr. Aiton’s retirement in 1841, his garden, library, record plant-
books, papers and drawings were removed to his own house, and on
his death in 1849 the whole of his immense correspondence was
burned by his brother, John Aiton. . . Some time after John
Aiton’s death, Mr. Attwell-Smith, Mr. Aiton’s heir, was pleased to
return them (the drawings and plant record books) directed to the
care of Sir W. Hooker. These drawings are now incorporated with
the immense collection of botanical drawings and prints preserved
in the Kew Library.”
There is a brief but interesting notice of Kew Gardens in Patrick
Neill’s ‘Journal of a Horticultural Tour,’ 1817. “We then looked
into the Botanic Garden, where I found Mr. Begbie the foreman, an
old acquaintance. The hothouses are not placed in any regular
form, but scattered over the garden. In one of them Mr. Begbie
drew attention to a plant o the Cactus cocldnillifer which had
been brought to Britain with the cochineal insect feeding upon it.
There was still a considerable number of the insect feeding upon
MABCH27, 1897]
PHARMACEUTICAL JOURNAL.
271
the plant. In another of the houses he showed os a new species of
Passiflora having edible fruit ( Passiflora edilis). The plant had
fruit upon it at this time. It is of an oval shape, purple coloured,
about the s'ze of a small hen’s egg. It has sometimes been served
up with the dessert at tbe Royal table.”
The first Himalayan rhododendrons were introduced in 1818,
Dr. Wallich sending the seeds of R. arboreum from Nepaul to Kew
and Edinburgh. The largest at Kew in 1889 was a tree twenty-
three feet high.
The present Kew Herbarium was originally Hunter House, the
property of Robert Hunter, a friend of the elder Aiton. At the
instance of Sir Joseph Banks, it was purchased for the King in
1818, and a room on the ground floor was fitted with bookshelves
in 1820, but apparently was not used at the time. Banks and the King
both died in 1820, and three years later George IV. sold Hunter
House to the nation. Its use for herbarium purposes did not
commence till 1852. The library of the Royal Gardens is an
addition to Hunter House on the north.
George IV. bought Hunter House within the garden area, closing
and throwing into the garden the old road from Kew Green to
Brentford ferry, and he erected iron gates in the centre of the green.
When in 1824 Professor Schultes of Landshut visited Kew, he was
“disappointed, particularly in the plants which grow in the open
air, which are not so accurately named as those in the Gottingen
Botanic Garden, superintended by Schrader : sometimes the same
species is marked with two different names. The garden at Kew
consists of a fine park and of a large botanical garden cf about
twenty acres. . . . The Botanic Garden at Kew is surrounded
by high walls and is intersected with long squares. With regard
either to its plan or its nine or ten stoves, it will not bear a com¬
parison with those of Malmaison, or the Grand Duke of Weimar, of
Prince Esterhazy at Eisenstaadt, or even with the botanical division
of the Imperial Garden at Schonbrunn.”
The Arboretum at the time of the Professor’s visit was about five
acres in extent, and contained the first introduced plant of Aucuba
japonica. The herbaceous ground was south of the Arboretum,
while the pleasure grounds extended from the Palace to the Pagoda
“for a full mile.” The Botanic Garden and Arboretum at that time
consisted of a series of enclosures surrounded by walls, most of
which have since been removed.
No collectors were sent out from Kew during the reign of
George IV., but two Kew gardeners, Frazer and Morrison, sent home
p’ants to it.
Thomas Frazer sailed for St. Helena in 1821, and on his return
brought back a twig of the weeping willow that grew by
Napoleon’s tomb. It was one of the lions of Kew till it was cut
down in 1867. He also introduced Buddleia madagascariensis, the
cabbage tree of St. Helena.
William Morrison in 1828 brought home from Trinidad a large
collection of seeds, plants, and dried specimens. When the Swan
River Colony was founded in 1829, Sir James Stirling, the Governor,
took Morrison with him as gardener. Through his instrumentality
many of the Swan River Proteacece were introduced at Kew.
William III. in the early years of his reign took a great deal
of interest in the gardens. A plan for a spacious palm house,
prepared by Wyatville, met with his approval, but the scheme was
subsequently abandoned, the KiDg removing from Buckingham
Palace the great architectural conservatory which stands near
the main gate. Up to the year 1848 it was used as a palm house.
Then the larger growing kinds of Australian plants, such as
Myrtacece, Leguminosce, and Proteacece. These were removed in
1863 to the Temperate House, and it is now kept for Aroidce and
other plants requiring an extreme tropical treatment.
A collection of living orchids was brought over from Trinidad in
1833 by George Aldridge. He was the son of John Aldridge, who
for many years was foreman of the Royal Kitchen Garden at
Kensington, and afterwards was Superintendent of the Royal
Kitchen and Forcing Garden at Kew.
George Barclay, gardener at Kew, 1833 to 1835, was in the latter
year appointed botanical collector to H.M.S. “Sulphur,” which was
about to proceed to western South America for surveying purposes.
The Sandwich, Fiji, and other Pacific islands were visited. Barclay
visited England with his collections in 1841.
Nathaniel Wilson, despatched to Jamaica to cultivate coffee in
1847, sent the tree fern and other fsrns, the lace bark tree and
many other plants home to Kew. He made a special study of fibre
plants, and his collections formed one of the earliest contributions
to the Economic Museums at Kew. Subsequently he became one of
the curators of the Botanic Gardens at Bath.
Aiton secured the opening of Kew Gardens to the public. In
1819 they were only open to tbe public every Monday during the
summer. By the year 1838 he succeeded in getting them open
unreservedly to visitors except on Sundays.
After the death of William III. a committee was appointed by
the Treasury to inquire into tbe state of Kew Gardens. It consisted
of Dr. Lindley and two practical gardeners, one of whom was Sir
Joseph Paxton.
They reported that the garden occupied “ fifteen acres, of which
part is Arboretum, and the rema'nder filled by stoves and green¬
houses, borders of herbaceous plants, Spaces left for the arrange¬
ment of greenhouses, plants in the open air in summer, offices,
yards, etc. The Arboretum contains many very fine specimens of
hardy exotic trees and shrubs, but the collection is not very
extensive, and the plants are too much crowded. The collection of
Herbaceous Plants appeared to be inconsiderable. A certain
number were marked with their names written on painted sticks,
others were unnamed, no systematical arrangement was observable
with the exception of Grasses, of which there is an extensive
collection named.”
John Smith, at that time foreman, and subsequently the first
curator of Kew after it became a national establishment, accounts
in part for the severity of the report by the fact that the preceding
winter had been one of the severest on record. “ The herbaceous
collection if it had been examined in summer and time taken,
would have been found to contain about 2500 species of the
perennial plants arranged according to the Linnasan system.”
The report said that the ten stoves and greenhouses were ex¬
cessively crowded, but admitted that the plants, especially those
from New Holland, were well attended to. From other sources we
know that the collections of Cape and New Holland plants were
incomparable.
Smith also showed that Kew had supplied many of the colonies
and botanic gardens of Europe with rare plants, e.g., Mauritius and
New South Wales, St. Vincent, Jamaica, and Trinidad received
European fruits suitable to their climate, and a large collection of
succulent plants was sent to Calcutta. The collections of European
Botanic Gardens were also enlarged by gifts from Kew. In 1<97
230 species of plants were sent to the Grand Duchess of Russia.
After the peace of 1814 Professors Wendland, of Hanover, I ischer,
of St. Petersburgh, Martins, of Munich, Link and Otto, of Berlin,
Reinhardt, of Leyden, and Sagasca, of Madrid, visited Kew from
time to time, and selected many species for their Gardens.
In 1839 Lord Surrey, the Lord Steward, tried to convert the
greenhouses and pits into vineries and pine stoves, but public
opinion forced him to desist. He actually offered the Kew plants
at first to the Royal Horticultural Society for the garden at
272
PHARMACEUTICAL JOURNAL.
[MARCH 27, 1897
Chiswick, then to the Royal Botanic Society for their garden at
Regent’s Park, but both learned Societies refused to accept them,
and in 1840 the Earl of Aberdeen obtained a guarantee in Parlia¬
ment that the plants would not be removed. A few days later, the
botanic garden was transferred to the charge of the Commissioners
of Woods and Forests, with the sum of £800 annually towards the
expense of maintaining the same.
Towards the end of 1840 Aiton resigned.
Sir William Hooker, Regius Professor of Botany in the University
of Glasgow, was then appointed Director of Kew, and a new era
opened for the Gardens.
THE LATIN OF PHARMACY.*
BY GEORGE COULL, B.SC.
“For ourselves, we can say that we have not shrunk from any
pains, with a view to the most perfect publication of this work :
not, however, so as to presume that it will content every one, nor
can we confidently assert that it is free from error ; which, if any
one note with a snarl, let him at least consider, not only the great
variety but the vast difficulty which such a work embraces ; and it
is to be hoped he will not be offended by a few trifling blemishes.
But we have said enough.” Thus runs part of the self-complacent
preface to the Pharmacopoeia Londinensis, 1809, translated by
Hector Campbell, M.D. Nowadays, those responsible, or rather
he who is responsible, for the compilation of the British Pharma¬
copoeia does not look upon fair critics as “ snarlers,” but gives
every suggestion made due consideration. Therefore, if any of my
criticisms appear too trifling, I am enboldened to believe that they
will not be considered “ noted with a snarl.”
English being now the language in which the national Pharma¬
copoeia is printed, the Latin in it is confined to the names of the
drugs, chemicals, and preparations it contains, yet even in this
limited sphere it might be amended. It is a great pity that there
is such a marked decadence in the knowledge and use of Latin in
medicine. It is possible that the Royal College of Physicians of
Edinburgh is responsible to a certain extent for this, as it was the
first of the three British colleges to issue a pharmacopoeia in
English. This occurred in 1839. Two years afterwards another
edition, the last E. P., was published also in English. The last
Dublin Pharmacopoeia, 1850, was likewise in the vernacular, while
the London College adhered to Latin down to the very last in 1851.
Mr. J oseph Ince, who stands easily first in the Pharmaceutical
Classical Tripos, believes the time will come when the official
pharmacopoeia of every country will be again issued in Latin,
though an edition in the vernacular might also be published ; con¬
sequently, in framing the nomenclature of a pharmacopoeia, the
genius of the Latin language should be followed as closely as
possible. To that I would add, never sacrifice the purity of your
Latin by exchanging a word used by the Romans for a manu¬
factured one in order to be consistent with the Latin of the pharma¬
copoeia. When, therefore, there is a good Latin word which the
Romans employed to express exactly the same thing that we use
the English equivalent for, why is a new word coined, as the
euphemistic term is ? In the Addendum, 1890, gelatine is intro¬
duced and latinised as gelatinum. I much prefer the term
gluten or glutinum, both classical Latin, or perhaps glutinum
pur ifica turn.
Bourn coriis glutinum excoquitur. — Plin.
Glue is obtained from the hides of oxen. This is practically the
definition of gelatin in the Addendum. Gray’s ‘ Supplement,’ 1831,
gives gluten commune for cake glue.
Some years ago a correspondent of the Pharmaceutical Journal
said resinum should replace resina. Imagine ! dismissing by a
scrape of the pen a word used by Pliny and Martial, in favour of
a mongrel production of the end of the nineteenth century because,
forsooth, it has the same termination as the alkaloids have. This
is where the craze for consistency lands us.
The introduction of the word oleatum has given rise to some
discussion regarding its suitableness. It does seem unfortunate
that we should have two Latin words in use, oleas and oleatum,
both translated oleate, but differing from each other chemically
and physically. The confusion is intensified by the genitive of
each being capable of contraction to oleat. Of course the B.P.
should be our guide, but such ambiguity is not desirable. I think
Pollard’s suggestion to revive the old word oleamen or oleamentum
for the official mixture of oleate and oleic acid — the so-called
oleatum — is eminently worthy of consideration, leaving the
English for it to the literary taste of the Editor of the Pharma¬
copoeia. Theriaca is given in Latin dictionaries as meaning
anything good against poisons, an antidote. It was afterwards
applied to special remedies and finally to a preparation of opium
flavoured with aromatics. ‘ Pharmacographia ’ says: “How it
came to be applied to molasses, we know not.” I would suggest
a return to the London and Edinburgh pharmacopoeial name
sacchari hex, or name it syrupus aureus or even molasses.
Another example of the introduction of a hybrid word in place
of a pure Latin one is antimonium for stibium. The derivation of
antimony is usually given, Gr. avri, against, and Fr. moine, a monk,
whilst stibium = otI(3i, was employed Dy Pliny and Celsus to desig¬
nate native sulphide of antimony. In the P.E. 1792, stibium was
given as the nomen vulgarium ; antimonium as the nomen pro-
prium ; in 1817 antimonium was said to be the nomen mutatum,
and sulphuretum antimonii, the nomen novum ; this was changed
in 1841 to antimonii sulphuretum, sulphuretof antimony. It is thus
seen that antimonium was applied to the native sulphide just as
stibium originally was. If therefore it is conceded that we ought
to use classical Latin when we can, then we should certainly revert
to the use of stibium. There has been a talk for many years now
of an international pharmacopoeia, and the adoption of pure Latin
words for official articles would help a little towards that most
desirable end. Kalium and natrium have not such a good case as
stibium, but considering that they are the names from which the
chemical symbols of the metals are derived and that they are much
used on the Continent I think we could adopt them without any
loss of dignity. There are other Continental fashions which meet
with almost universal disapproval, one of these is that
(to my ears) uncouth way of naming salts, as magnesium
sulphuricum, kalium carbonicum, ammonium choratum for
magnesii sulphas, potassii carbonas, ammonii chloridum respec¬
tively, or the equally abhorrent magnesicus sulphas. There is a
growing tendency to take Germany as an authority on spelling in
chemistry, this is more apparent in the United States than here.
The present U. S. P. has naphtol and naphtalinum included for the
first time, and spelt in the German text-book manner, though I am
pleased to note the ‘Arzneibuch’ retains the ultimate “ h” in these
words. Now I protest against this copying of German spelling.
The word was spelt vapda by the Greeks, naphtha by the Romans,
and it is naphtha in our own language. I hope, therefore, that
our authorities will make a firm stand against this Teutonic
degradation of the word.
We occupy a position of “ splendid isolation” in regard to the
gender of nouns in -as -atis by making them feminine in defiance of
the pharmacopoeias of the world ; and I say if we are convinced we
are right, let us maintain that position. I am reluctantly compelled
to join issue with Mr. Ince on this matter. In an article in the
Journal* some years ago, he comes to the conclusion that because
all other countries make carbonas masculine we ought to do the
same. The only trustworthy evidence adduced was in favour of
its remaining feminine, viz. , if it made the genitive in atis then
there was no doubt it ought to be feminine. Professor Oldberg’s
opinion was quoted, it was only an opinion and backed by no proof
whatever; “that as there was no classical authority, there was
nothing to prevent him making carbonas masculine or any
gender he pleased. Let them stand as masculine ” was Oldberg’s
ipse dixit. When I state that this gentleman read a paper before
the American Pharmaceutical Association in 1889, in which he
gravely suggested abandoning the use of the genitive entirely, I
am altogether astonished that a purist like Mr. Ince should have
cited him as a witness. As this is rather an important matter not
on account of the issue depending on its settlement, but on the
principle of deciding between right and wrong, it is necessary to
consider the evidence for and against the different genders.
Pharmacopoeias are not of much use in deciding which gender is
correct, as they change about in quite a bewildering manner.
P.E. 1817 gave it masculine, carbonas ferri prajcipitatus ; 1841
changed it to neuter, ferri carbonas saccharatum ; P.D. 1826 also
made it neuter, calcis carbonas prcecipitatum. The P.L. 1809 to
1851 most consistently and correctly gave it feminine, sodse
subcarbonas exsiccata in 1809 and 1824, and sodae carbonas exsiccata
in 1836 and 1851. It was masculine in the U.S.P. 1850, feminine
in 1860 and 1870, and back to masculine in 1880 and 1890.
The first published criticism on the latinity of the B.P. 1885
was by an anonymous correspondent in the Journal, + signing
himself “X. Y. Z.” His letter was taken up solely with
* Read before the Glasgow Pharmaceutical Association.
* Pharmaceutical Journal [3], xx., 871.
t Pharmaceutical Journal [3], xvi., 324,
Mabch 27, 1897]
PHARMACEUTICAL JOURNAL.
273
the gender of nouns in -as. He submitted that they are by
form substantives of the third declension, to which the
feminine gender is least appropriate. They certainly are nouns of
the third declension, but nearly all nouns in as of that declension
are feminine. “ X. Y. Z.” said that the nearest approach to them
is latinised Greek nouns in as, that they approximate more to
adamas, or still more closely to fas and nefas, which are neuter.
He therefore submitted that carbonas, sulphas, tartras, etc., are
neuter. Now the rule given in Latin grammars is — nouns in as are
feminine, except vas, vasis, which is neuter ; the other exceptions
are Greek nouns in as -Stis, which are neuter ; nouns of Greek
origin in as -antis, as adamas -antis, which are masculine, as are
also nouns in as of the first declension. Fas and nefas follow the
rule, according to which all indeclinable nouns are neuter. Thus
“ X. Y. Z.’s” criticism is disposed of. Further, derivative words
usually retain the quantity of the words from which they are
formed ; we have carbo -onis, therefore carbonas. Again, as in the
end of a word is long, as piStas -atis, therefore carbonas -atis. I
repeat, then, Mr. Ince’s words that if we are to use Latin we ought to
follow the genius of the language ; and I would- add, follow the
ordinary rules of grammar in determining gender instead of adopt¬
ing arbitrary methods of settling that point at each revision of a
pharmacopoeia. It would be interesting to know upon what
grounds the U.S.P. Revision Committee in 1880 stated that
“ it had been shown that the change to feminine in 1860 had been
based on error.”
There are several cases where the latinity of the Pharmacopoeia
is obviously weak. Argenti et potassii nitras should be nitrates.
Liquor arsenii et hydrargyri iodidi should have iodidorum ; it was
introduced into the P.D. as liquor arsenici et hydrargyri hydrio-
datis, and when included in the B.P., 1885, the opportunity was not
taken to correct the grammar, although the nomenclature was
altered to make it consistent with modern custom. The B.P.C.
Formulary Committee rise to the occasion with their syrupus ferri
et quin into hydrobromatum and their syrupus ferri, quinin* et
strychnin* phosphatum. The Latin of the formulary is very good,
but I should like to know the principle by which cascara sagrada
is considered indeclinable, while guarana is capable of declension.
Because lapis calaminaris prseparata is given as a synonym that is
no reason for making lapis feminine. But perhaps it has been
done intentionally to make it “ consistent ” with calamina
pr separata, or taking a more generous view of the matter
let us think it was purely an oversight, which, although
very trifling, should not have occurred. Uv* is the
official name for raisins, following the precedent of 1864
and 1867, and uvse pass* is given as a synonym because it
was the term used in various London and Edinburgh pharma¬
copoeias. In Latin dictionaries uva is given as meaning a bunch
or cluster of grapes. Pereira and ‘ Pharmacographia ’ translate
raisins as uv* pass* ; when necessary to distinguish them from
currants they are called uv* pass* majores, the latter being uv*
pass* minores. Fliickiger and Hanbury further inform us that
the Hebrews were acquainted with raisins, uv* pass* occurring
in the Vulgate, and being rendered dried grapes to distinguish
them from fresh. Uv* pass* ought undoubtedly to be promoted
to the position of official name, and uv* dismissed altogether.
Ovi albumen is translated egg albumen, and described as the
liquid white of egg in the B.P., its sole use being for making the
solution of albumen in the appendix. Here again’ we have an
example of the sacrifice of a good classical term for a coined word ;
ovi album was used by Celsus for white of egg, and why should
not we do so also ; besides, it would be more consistent with ovi
vitellus, yolk of egg.
Shortly after the present pharmacopoeia was published in 1885,
several complaints were made regarding the gender of rhamnus,
the critics declaring that it should be feminine. Rhamnus pur-
shiana has been included in the U.S.P. , 1890. Smith gives
rhamnos i f. = pdfivos, buckthorn, and does not give rhamnus
at all. Ainsworth gives rhamnus i m., and Latin gram¬
mars, including Smith’s ‘Principia Latina,’ after the rule which
says names of trees are feminine, expressly state that rhamnus is
masculine, cytisus and rubus are generally masculine, and larix,
lotus, and cupressus are sometimes masculine. It is considered
masculine by Christison and Pereira, and all the specific adjectives
I have come across are masculine — niger, sanguineus, infectorius,
amygdalinus, catharticus, etc. So upon the whole I think it
should be allowed to stand. It was Saul who said that “ modern
Latin scholars are agreed that rhamnus is feminine, and ‘ Pharma¬
cographia ’ had recognised this by styling buckthorn rhamnus
cathartica.” Pollard, in replying, said that “modern Latin
scholars may agree to use the feminine if they please, but they
cannot make the language wrong that was used by the Romans.”
I most heartily endorse Pollard’s remarks.
Then, again, why have we departed from the old way of declining
rosmarinus ? Is this also due to modern scholars ? Besides the
fact that oil of rosemary was in the P.E., 1792, as oleum
essentiale summitatum rorismarini, and in 1817 as oleum
volatile rorismarini officinalis, and the spirit was in P.L., 1746 and
1788, as spiritus rorismarini (it was in 1809 that spiritus rosmarini
first appeared), we have the authority of Horace, Od. 3, 23, 16, for
marino rore, and also Columella, a writer on husbandry who
flourished about the same time as Horace, for rorismarini. Pliny
calls it rosmarinum, which, as ros is masculine, cannot be declined
as two. words, but simply as one. If, however, we retain ros¬
marinus as the nominative, the genitive ought surely to be
rorismarini.
(To be continued.)
LEGAL INTELLIGENCE.
PROCEEDINGS UNDER THE PHARMACY ACTS.
Alleged Unlawful Sale of Poison.
Pharmaceutical Society v. Lyons.
At the Bow County Court on the 22nd inst. before His Honour
Judge French, Q.C., the Council of the Pharmaceutical Society of
Great Britain sued James Lyons, of 36, Green Street, Upton Park,
chemist’s assistant, for selling poison contrary to the provisions of
the Pharmacy Act, 1868.
Mr. T. R. Grey, instructed by Flux, Thompson, and Flux,
appeared for the Society. Defendant appeared in person.
Mr. Grey stated that the action was for a penalty of £5 under
Section 15 of the Pharmacy Act for selling poison. Defendant was
an unqualified assistant in the employ of Mr. J. James at 36, Green
Street, Upton Park, where he sold poison, viz. “ Laudanum.” By
the 15th Section of the Statute it was made unlawful for any
person who was not a registered chemist and druggist to sell poison.
There was only one case that it was necessary to call the attention
of the Court to, and that was the case of the Pharmaceutical
Society v. Wheeldon, which decided that the unqualified assistant
of a qualified master who in the absence of his master sells poison
is liable for penalties.
His Honour : What becomes of the penalties ?
Mr. Grey : Section 14 of the Act of 1852 deals with the applica¬
tion of penalties.
His Honour : How do you make defendant liable?
Mr. Grey: Defendant sold the poison — he was not acting
under the supervision or control of any qualified person, and his
employer was miles away.
His Honour : Is a chemist not entitled to have any assistant he
likes ?
Mr. Grey : Of course he may employ whom he likes, but an
unqualified assistant may not sell poison ; if he does he is liable.
His Honour (to defendant) : Did your master superintend your
making up this mixture ?
Defendant : No, he was at the other shop.
His Honour (to Mr. Grey) : Prove your case.
John Partridge (examined by Mr. Grey) : I went to 36, Green
Street, Upton Park, on November 14 last. It was a chemist’s shop.
There was only a boy in the shop when I went in. Defendant
came from the back of the shop. I asked him for two-pennyworth
of soap liniment and two pennyworth of laudanum. Defendant
put the articles together in my presence. I sealed the bottle up
on the evening of the day on which I made the purchase. I handed
the bottle to the analyst. It was as I received it except for the
sealing-wax over the cork and the date which I put upon the label.
His Honour : Did you require this for your own purposes?
Witness : No. I was sent by the Pharmaceutical Society to
make a purchase.
Mr. E. J. Eastes, F.I.C., examined by Mr. Grey: I am an
analyst. I received the bottle from last witness. I carefully
analysed the contents, it contained soap liniment and laudanum. I
determined the laudanum by the presence of “morphine.” There
was nearly half an ounce of laudanum in the bottle.
274
PHARMACEUTICAL JOURNAL.
[March 27, 1897
His Honour : Half an ounce of laudanum for twopence ? What
is the price of laudanum ?
Witness : It varies from 4 d. to 6 d. per ounce.
His Honour (to defendant) : What do you charge for laudanum ?
Defendant : Sixpence per ounce ; one-third of an ounce for two¬
pence.
His Honour (to Mr. Grey) : Do you ask me to convict on this
evidence ; this is not, to my mind, a bona-fide, purchase ? It has
remained in the possession of the witness, and when analysed the
analyst finds more laudanum than the defendant says is sold for
twopence at the shop where he is employed, and he is not told any¬
thing- about it until some time after.
Mr. Grey : The fact of the purchase was reported to the Society
within a day or two afterwards. The case had then to be con¬
sidered by the Council at their next meeting, and on December 15
defendant was written to on the subject. He did not reply, but a
correspondence took place with his employer, and as his employer’s
answers were not satisfactory these proceedings had to be taken.
His Honour : Can you get satisfactory evidence in a case where
there is an interval of a month between the purchase and calling
defendant’s attention to the fact ? How can he possibly remember
what he did a month back ? It should have been brought to his
attention immediately, and if the matter had to go before the
Council someone ought to have been deputed to bring the matter
to his attention. I give judgment for the defendant.
PROCEEDINGS UNDER THE FOOD AND DRUGS ACTS.
The Sale op Lime Cream and Glycerin.
At Brentford Police Court on Saturday, before Mr. Montagu
Sharpe, in the chair, and other justices, J. Wilkey Webber, che¬
mist, of 202, High Road, Chiswick, was summoned for having
sold to Walter Tyler, an inspector under the Food and Drugs
Act, lime cream and glycerin not of the nature, substance, and
quality demanded.
Mr. G. W. Lay defended.
The facts, with the exception of the analyst’s certificate, were
admitted. The Inspector’s assistant purchased for Is. a bottle
labelled “Lime Cream and Glycerin, for cleansing and strengthening
the hair. This cream renders the hair beautifully soft and glossy,
having the properties of a wash as well as a pomade.” Then
followed directions for use and the name of the defendant as maker.
The sample was divided into three parts, one being sent to the
analyst, who certified, “ I am of opinion it contains no glycerin.”
For the prosecution it was contended that this was a drug, and
that the purchaser was shown, by the certificate, to have been
prejudiced.
Inspector Tyler, in cross-examination, admitted that he had
taken many samples of defendant’s drugs, and always found them
good and correct. Previously the shop was kept by Mr. Wooster,
and for the last three years by the defendant. He held glycerin
to be a drug because it was mentioned in the British Pharma¬
copoeia.
The Chairman : This is a hair wash, isn’t it ?
Mr. Lay : A very superior sort. Not the ordinary kind at 4 \d.
a bottle.
The defence set up was that the compound contained glycerin,
actually added, and not left to be produced by saponification, or the
action of other drugs. It was made from a recipe that had been in
the possession of Mr. Wooster for twenty-five years, and was passed
on to the defendant with the sale of the business. The formula
consisted of “nut oil, 4 oz. ; lime water, 4oz. ; saccharated lime
solution, 40 drops ; perfumes (oil of bergamot and limonis), 25
drops ; and glycerin, half a teaspoon, equal to half a drachm.”
This recipe had never been questioned. The portion of the sample
left with the defendant had been submitted to analysis, and though
the certificate could not be produced as evidence, as a fact the
analyst had certified it contained glycerin.
Herbert Edward Wooster, in the employ of the defendant,
deposed that he made up the compound from the recipe quoted,
and he put half a drachm of pure glycerin into the mixture.
Mr. T. Cunnington (one of the justices) : What quantity was it?
■ — An eight-ounce bottle.
The Chairman : How do you know this was the very bottle ?— I
can identify it as the particular bottle. I make a certain number
of bottles. I identify it by its appearance.
The Chairman : You might have made a mistake in your
mixing ? — I might, but I have made up a great number with per¬
fect correctness.
The Chairman : Do you make a general quantity and fill into
bottles ? — Yes ; four pints, and then fill the bottles.
The Chairman : Does anyone else make up or help ? — No, sir.
Mr. Cunnington : Do you say you put that quantity of glycerin
into each bottle or into the lot ? — Into the lot.
Mr. Cunnington : In what proportion is the glycerin ? — Equal
to half a drachm to the eight-ounce bottle.
Mr. Cunnington : Do you keep stirring ? — Yes.
Mr. Lay : It doesn’t evaporate ? — No.
The Chairman : Does it float or sink ? — It mixes with it.
The Chairman : You might have been called out when mixing
and might have forgotten to put the glycerin in ? — I was not called
out.
Cross-examined by Inspector Tyler : He was sure the bottle in
question was not one left from a previous mixing. He could not
swear to the day he made it up.
Mr. Tyler : Is it not a fact that glycerin must be kept moving ?
—No.
Mr. Tyler : Must you not keep it moving, stirring it up to get
a fair proportion ? — -Yes.
Mr. Tyler : Do you put glycerin itself or some substances to
produce it ? — Glycerin pure and simple.
The Chairman : Is glycerin heavier or lighter than the other
ingredients ? — Heavier. It would sink.
Mr. Montgomery (on the Bench) : Do you keep shaking the
Winchester bottle, in which you mix before bottling ? — Yes.
The defendant, sworn, deposed that nobody but the last witness
prepared the compound. He had had his portion analysed, and it
contained glycerin.
Mr. Cunnington : Do you use Price’s or that made in Germany ?
■ — Price’s.
Inspector Tyler : You are certain your assistant did not use
olive oil ? — W e do not use it. It would discolour the compound.
We use nut oil, because it makes it white.
Inspector Tyler : Do you know olive oil is used in place of
glycerin ? — I have not heard it.
Inspector Tyler : You would be surprised to hear that it is put
in as a substitute for glycerin ? — Most decidedly.
Inspector Tyler : You do not put your recipe before the Bench
as any authority for this compound ? — It is the only one we use,
and has been used for twenty-five years.
Inspector Tyler : It would not over-ride the British Pharma¬
copoeia? — The British Pharmacopoeia does not contain lime juice
and glycerin.
Inspector Tyler : Do you dispute the analyst’s certificate. Do
you say it is wrong ? — Yes.
Inspector Tyler : On what grounds ? — I say glycerin is present.
Inspector Tyler : Upon the supposition that the certificate of
the other analyst is correct? — No. Upon general evidence? — I
have always had the greatest confidence in my assistant, and I
have never found him inaccurate.
Inspector Tyler : Therefore you entirely dispute the public
analyst ? — I do.
Mr. J. R. Wooster, formerly owner of the shop for twenty-five
years, gave corroborative evidence.
Mr. Lay submitted he had proved his case. If the Bench were
against him he would have the remaining portion of the sample
sent to Somerset House. It would be better perhaps, in view of
the conflicting certificates, to have independent evidence.
The Chairman : Is it obligatory for us to assent ?
Mr. Lay : I think so. Either dismiss or send it.
The Chairman : The Act says “ may in our discretion.” There¬
fore it is not obligatory.
Mr. Lay : It has never been refused.
After a consultation, the Bench acceded to the request, and the
summons stood adjourned.
Substitutes for Iodoform. — Among the countless substitutes
which have been suggested to replace iodoform, the following
have some claim to distinction as preparations which have proved
themselves of really good effect: — Iodol, trichlorphenol, tri-
brompbenol, tribromphenol bismuth, sodium sozoiodol, zincum
sulfocarbolicum, sulfaminol, aristol, euphorin, pyoktannin, der-
matol, salol, europhen, guaiacolcinnamate, thioform, loretin,
airol, iodoformin, nosophen, actol, itrol, glutol, glutoform, and
many others.— Joum. d. Pharm. v. Elsass Loth, xxiv., 5, after
PJiarm, Post,
March 27, 1897]
PHARMACEUTICAL JOURNAL.
275
NATURAL HISTORY NOTES.
( Continued from page 177.)
Protecting Rare Species. — The fortunate discoverer of a
rare specimen should be somewhat slow to give too precise
details as to locality and means of access thereto to all comers,
and should, of course, be himself the last to take more than
sufficient for a specimen. If this method were loyally fol¬
lowed the danger of extinction which now threatens certain of
our rarer flora and fauna would be removed.
Plans for Next Season. — During this the winter of our dis¬
content we are naturally looking forward to the renewal of our
campaign during the coming summer. Botanists who are fairly
well acquainted with the general flora of their district will do well
to select some special genus for study, or even, if opportunity for
excursions are few, for the study of the life history of some parti¬
cular plant. Those who have read that charming story ‘ ‘Picciola ”
will remember how the unfortunate prisoner consoles himself during
his captivity by watching the growth of a plant ; so the pharma¬
cist, who is a prisoner to his business, may in a like manner obtain
recreation by following out the life history of almost any of the
commoner plants. Carefully recorded notes on the subject would
possibly be of general interest.
Drosera Growing. — For this purpose few plants are more inte-
resting than the common sundew, Drosera rotundi folia, which is
easy to grow if properly treated, flourishing well on a sunny
window-sill, provided that it is kept well supplied with water.
Both D. rotundifolia and D. intermedia have been grown in the
following manner : — Take a large flower-pot twelve inches in
diameter and fill it to depth of four or five inches with small coke,
then fill up in the ordinary way with peaty loam, and on the sur¬
face lay the plants with as much sphagnum or whatever vegetation
they may be growing in, as can be conveniently removed from the
native bog. Stand the flower-pot in a large tamarind jar and keep
this latter always well filled with water. In this way a miniature
bog is formed, in which droseras, Campanula hederacea, and
Anagallis tenella will flourish in vigorous health.
Is Drosera an Anneal ? — In this manner individual plants of
Drosera, after flowering and fruiting, survived the winter and went
well on into the spring, showing small curled-up leaves in March.
Here, however, illness on the part of the observer interrupted the
record, and the plants, like “ Picciola,” died for want of water.
Drosera is generally reputed to be an annual, but this would seem
not to be the case.
Spread of Immigrant Plants. — Another interesting point that
is worthy of attention is the appearance of new plants, “not as
single spies, but in battalions,” and also, alas, the disappearance of
others. Thus some eight or nine years ago, Impatiens fidva was
only found in certain districts in the Lower Thames Valley. Now
it is almost ubiquitous, and may be seen in any wet ditch.
From casual observation this would appear to be a plant
worthy of further study. It appears to be cleistogamous.
A few wild seedlings transplanted one year to a garden produced
ripe seed pods early in the summer from minute yellow flowers,
which scattered their seeds broadcast on the least touch long
before the conspicuous red flowers made their appearance in the
autumn. These latter apparently produced no mature fruit. But
the following year the same wet border was overrun with seedling
balsams, which could not well have originated but from the early
seeds of the first planted specimens.
Absent Plants. — In the same district Anemone nemorosa is now,
unfortunately, conspicuous by its absence. This can scarcely be
through being plucked, since the beautiful plant is plentiful enough
in Highgate Woods and in all the copses north and east of London.
But it is not to be seen in the enclosed coppices of Richmond or
Bushey Park, nor is it common in the plantations of the district
unless introduced. Primroses also but rarely gladden the eyes of
the Cockney botanist within the twelve-mile radius. W ithin the
last ten years Butomus umbellatus was to be found on the London
side of Richmond Bridge, but we do not see it now. On the
other hand, Salvia darica, which Gerarde used to find on the banks
of the Thames in London, still holds its own on the towing-path
higher up the river.
Experiments on “Sugaring” for Moths. — Some of our
friends might be induced to try experiments on attracting moths
by the well-known method of “ sugaring.” The compound for this
purpose in the old days was foots sugar, treacle, and beer, boiled
together to a thick syrup. Just before using, a dash of rum was
added. Someone, however, being away from any source whence
rum was obtainable, used ordinary methylated spirit instead ; to
his surprise, this proved even more attractive, and it is now
universally used. It has been found that the substitution of
crude honey for the foots sugar and the addition of a few drops of
butyric ether to the methylated spirit effects a great improvement as
a lure. The matter is worth further investigation. Experiments
with essence of jasmin, artificial pineapple, and of raspberry, also
with valerianic acid, gave no better results than “blank” sugar¬
ing, but butyric ether was decidedly to the taste of all the common
noctuce. Red and yellow underwings absolutely fought for
a place at the patch which was painted with the usual mixture
containing the addition of a few drops of butyric ether, while
others without this addition were almost unvisited.
PARLIAMENTARY NOTES AND NEWS-
Dr. Farquharson is not satisfied that the cases of rabies
recently reported in the Metropolitan District are genuine cases,
and he proposes to ask the President of the Board of Agriculture
on what evidence the diagnosis was based. On poetical authority
we have it that “great genius is to madness near allied,” and
possibly the genial member for West Aberdeen may have a- lurking
suspicion that certain canine eccentricities are thoughtlessly inter¬
preted as symptoms of insanity by unscientific observers. At any
rate, the President of the Board of Agriculture is to be invited to
state how often the certifying surgeon has been able to base his
conclusions on symptoms observed during life, and how often on
an examination of the nervous centres of the suspected animal in
accordance with the scientific methods practised at the Brown
Institute.
The Sale of Food and Drugs Bill, of which Mr. Kearley is
the Parliamentary pilot, was down for second reading on the 18th
inst. , but was not reached, for the more exciting items of Crete
and Voluntary Schools had prior claims on the attention of honour¬
able members. The second reading has now been deferred to
April 2, a most unfavourable day for a private member’s Bill, seeing
that the House will be in Committee of Supply, and will be fully
occupied with Government business.
Companies Bill. — At the meeting of the House of Lords Select
Committee, on Monday 22nd inst., Lord Justice Lindley and Mr.
Justice Romer were examined as to their opinion of the Govern¬
ment Bill to amend the Companies Acts. The former was very scath¬
ing in his denunciation of “ One-man ” companies, and was not alto¬
gether complimentary to the House of Lords when he stated that
he could not think it was the intention of the Legislature to enable
an individual trader by indirect means to trade with limited liability.
The Lord Chancellor invited the witness to explain what public
evil was caused by one man practically holding all the shares in a
company, and Lord Justice Lindley, in reply, expressed his con¬
viction that it was dangerous for one man to be the sole trader in
the form of a company. This unofficial dictum of a Lord of the
Appeal Court is refreshing, coming as it does after the decisions in
Salamon’s and in Wragg’s case. The Committee did not have the
question of professional titles before it, or Lord Lindley might
have thought it equally iniquitous for one man to “ indirectly ” steal
a title as to “indirectly” rob his creditors. Mr. Justice Romer
approved of the Bill as a whole, with certain modifications toning
down the stringency of the provisions dealing with directors’
liability. The Committee meets again on Monday, the 29th —
unheard-of activity- — and will probably take more expert legal
testimony.
The Easter Recess will commence on April 14, and the House
of Commons will re-assemble on the 26th of the same month a
very moderate rest for weary politicians.
Early Closing.— All three Bills are tabled for second reading
on Friday, 26th inst. The blockade against the Shops (Early
Closing) Bill of Sir J. Lubbock, and the Shops Bill of Sir C.
Dilke and Co. still continues with undiminished rigour. There is
absolutely no chance for the blockaded measures, and very little
for the unopposed half -holiday project of Mr. Buncombe.
276
PHARMACEUTICAL JOURNAL.
[Mabch 27, 1897
THE STUDEHTS’ PAGE.
maturity. The male flowers consist of eight stamens, with two
small bracts overlapped by a larger hairy one. These are well
shown in Kitchener’s ‘ A Year’s Botany,’ pp. 79-81.
SOME NOTES ON CRYPTOGAMS.
For students having botanical tastes the present is a dull
season, from dearth of fresh specimens. Those having microscopes,
however, may with advantage turn their attention to cryptogamic
botany, and will find no difficulty in obtaining plenty of material in
a suitable state of development for purposes of study. The
mode of reproduction by gemmse is here illustrated by sketches
of some interesting specimens. Amongst mosses, Aidacomnion
Fig. 1. — Aulacomnion An- Fig. 2. — Lunularia vulgaris.— A, fruit-
Drogynum.— A, plant in fruit ; ing stage ; B. frond bearing gemmae ; C,
B, gemmae ; C, do., magnified. magnified gemmae.
androgynum (Fig. 1), which grows on shady banks and rocks, may be
had in the gemmiferous state (Fig. 1, B), the fruit (Fig. 1, A) being
produced in May or June, whilst of the
Hepaticse quite a number of species are
obtainable. Perhaps the most easily ob¬
tained, because widely distributed, are the
scale moss, Kantia trichomcmis (Fig. 3) and
the liverwort, Lunularia vulgaris (Fig. 2),
both of which may be found on damp banks
and rocks, and on flower-pots in green- Fig- 3.— Kantia tri-
houses. In the case of the latter, the ?nHg°“ r01ld bear’
gemime are borne in semi-circular cups on
the fronds. The fruiting state of Lumdaria is represented by
Fig. 2 (A), but the plant is rarely found in fruit. Fig. 1 (C)
represents highly magnified gemmse of Aidacomnion, Fig. 2 (C)
those of Lumdaria.
THE FLOWERS OF MARCH.
The Euphorbiaceae are represented by a somewhat abnormal
species, the Mercurialis perennis, which has rather the habit of
the Urticacese, having opposite leaves with interpetiolar stipules,
and a watery juice, but in Urticacese the fruit is always one-celled
and one-seeded. In Mercurialis it is two-celled. The flowers of
Mercurialis are unisexual, and usually occur on separate plants.
In the male plant the flowers are arranged in conspicuous axillary
spikes. Each flower consists of three bracts, and of nine to twelve
stamens. The female flowers usually occur on individuals having
larger leaves of a darker green hue. The flower consists
of three bracts, with two barren filaments and an ovary
of two hairy carpels, and two stigmas. The plant spreads
widely by means of its slender rhizome. The leaves yield a
blue colouring matter soluble in water, which is turned red
by acids, and destroyed by alkalies (Pharm. Journ. [3], viii.,
p. 665). Another plant of the same natural order, usually in
flower this month, is Buxus sempervirens. The flowers of
the hazel should be examined during this month. The male
catkins are evident enough, but the female catkins may
easily be overlooked. These may be recognised by the crimson
stigmas protruding from some of the buds. These buds, when
dissected, are found to contain five or six flowers, each with two
stigmas and a two-celled, two-seeded ovary, surrounded by an
adherent calyx, and furnished with a bract, which ultimately
forms the cupule, only one seed and one cell being developed to
NOTES ON THE PHARMACOPOEIA.
Calcii Chloridum. — Distinguish this carefully from “chloride
of lime ” — the common disinfectant — which evolves chlorine on the
addition of hydrochloric acid.
Calcii Sulphas. — The native sulphate, gypsum, CaS04,2H U,
loses the water of crystallisation when heated, and the anhydrous
sulphate, known as ‘ ‘ Plaster of Paris, ” is very largely used for
making moulds and casts, because when mixed to a creamy con¬
sistence with water, the mixture solidifies in a short time (varying
with the amount of water added), owing to the re-formation of the
hydrated salt, which ‘ ‘ sets ” to a coherent mass of interlocking
needle crystals. The heat used for dehydrating the gypsum should
not be too high, below 200° C. is best, otherwise the product when
mixed with water sets too slowly, and if a red heat be employed,
this property is entirely lost. Commercial 1 ‘ plaster ” usually
contains 4 or 5 per cent, of water (CaS04, 2H20 = 20 '9 per cent,
water), and if exposed, especially to a damp atmosphere, it absorbs
more and sets more slowly.
Calx Sulphurata. — The small dose relative to other calcium
compounds on the one hand, and sulphur on the other, is chiefly
due to the ease with which sulphuretted hydrogen is evolved by
the action of the hydrochloric acid of the gastric juice. A very
much larger quantity of free sulphur is required to produce the
same effect, but a very small quantity of H2S goes a long way in
the breath and excreta of a patient.
Cambogia. — The formation of an emulsion with water, and
solution by the successive action of rectified spirit and water are
typical of gum resins in general. If starch be present the
addition of iodine produces a green colour, by combination of the
blue colour of the iodide of starch with the yellow of the gamboge.
Cataplasmata. — These preparations are not so frequently em¬
ployed in medical practice as formerly, and the formulae might well
be omitted from the next edition of the Pharmacopoeia. In hem¬
lock poultice the juice of hemlock is evaporated in half its volume,
presumably to remove the alcohol. In yeast poultice tepid water
is employed, since boiling water would kill the yeast. For a
similar reason mustard should not be mixed with boiling water,
since the activity of mustard depends upon the development of
essential oil, the latter being a product of the decomposition of the
glucoside sinigrin, under the influence of a special albuminous
(proteid) ferment. This ferment is coagulated and rendered in¬
soluble, like the proteids of egg albumen, at the temperature of
boiling water. In this condition it is incapable of exerting its
specific action upon the glucoside.
Chloral Hydras. — Chloral is trichloracetic aldehyde, CC13C -0 'H.
Chloral hydrate, CC13CH<^q^ or CC13C0H'H20, exhibits an un¬
common feature, namely, the presence of two hydroxyl groups'
combined with the same carbon atom. As a general rule attempts
OH
to prepare bodies containing the group = C<^qjj result in the pro¬
duction of the carbonyl group = CO, the elements of a molecule of
OH
water separating (compare carbonic acid, 0C<qjj = C02 + H20).
When chlorine (or some other negative element or group) is united
to a neighbouring carbon atom the formation of the group
OH ^
= C<^q^| is rendered possible. Chloral hydrate is decomposed by
heat, as indicated by its vapour density, into chloral and water.
Chloral hydrate is decomposed by alkalies into chloroform and
formic acid.
CCl3CH(OH)2 + KOH = chci3 + h2o + hco-ok.
CCL
H
CH<gg
OK
.OH /O
Note the breaking up of the — CH<^ into C^ _ and H20 when
the chlorine is removed.
NOH
VH
March 27, 1897]
PHARMACEUTICAL JOURNAL.
277
Pharmaceutical Journal.
LONDON: SATURDAY, MARCH 27, 1897.
CONSIDERATION FOR THE “ POOR ” CHEMIST.
So far the discussion of the proposed new bye-laws has
not furnished evidence of any disposition on the part of
chemists and druggists to respond to the factious invocation
to|“ strike a blow for justice ” by opposing the amendments
which the Council has declared to he requisite in regard to the
Preliminary examination and the fee payable for qualification
under the Pharmacy Act, 1868. On the contrary, there have
been very decided expressions of approval and of anticipa¬
tion that the changes proposed will meet with general support
throughout the trade. The representations put forward with
the object of exciting opposition have been declared to be as
inappropriate as they are misleading, and the statement of
facts in connection with the cost of the Society’s Journal,
published last week, sufficiently proves those representations
to be without foundation. The remarks made to that effect
by Mr. Taplin in opening the discussion at the Western
Chemists’ Association were heartily re-echoed at Cambridge
last Friday and, on both occasions, the desirability of still
further changes in the same direction, requiring amendment
of the Act, was pointed out by several of the speakers.
On the subject of the Preliminary examination there
is perfect unanimity of opinion that the proposed change is
absolutely essential and calculated to be advantageous in every
respect. ’ The only point in regard to which there has not
been equal unanimity as to the increased fee for qualification,
was the possible effect of the larger fee upon men to whom
the extra five guineas would be “ a great consideration.” On
that point Mr. Andrews prefers to keep an open mind
for the present, though he is otherwise entirely in accord
with the proposals of the Council. He spoke of having know¬
ledge of chemists so poor that their continued existence was
very precarious, though they were of service to the public
in their locality, and he fears that if such men desired
to bring up their sons to the business the extra fee
for qualification would press hardly upon them. For
these reasons Mr. Andrews thought that consideration for
the public, as well as for chemists in such a position as he
referred to, might render the propriety of the increased
fee questionable. This sentiment commands sympathy
on the ground of common humanity, but there are stronger
reasons for maintaining that there should be no occasion for
making the poverty of chemists, even in the poorest locali¬
ties, a ground of objection to an increased qualification
fee. The business of a chemist and druggist, as carried
on individually under some conditions, cannot be very
lucrative ; but the responsibility attaching to it demands
that adequate remuneration should be secured to those
who elect to carry on business under such conditions.
In the sense that Mr. Andrews made use of the term “poor”
there should indeed be no poor chemists. Such a condition
is as inconsistent with the nature of the duties chemists have
to fulfil as it is undesirable in the interests of the public
and of the craft. Two or three chemists in a poor locality
where even one would be unable to keep an assistant, might
indeed be reduced to the alternative once described by
Mr. Barnard Proctor as that of eating their neighbours
in order to avoid being eaten, but that is a condition of
things which should be prevented as much as possible. The
mischief is in there being too many chemists, and it is
inexpedient, either in the public interest or for the
interests of chemists, to facilitate increase in the number
of those whose conduct must be directed by the exigence of
poverty rather than by ability and desire to uphold the
character of the calling to which they belong. One of the
earliest forms of expression given to the object of the
Pharmaceutical Society, was that it should increase the
“ respectability of chemists and druggists.” That was in every
sense a laudable object, and its attainment has been
steadily progressing, notwithstanding many obstacles.
Increase of the qualification fee would have a beneficial
influence in the same direction by making the. corre¬
sponding requirements matter for consideration before appren¬
ticeship. A consequent limitation of the number of
chemists would also be a legitimate means, perhaps the only
attainable means, of securing such protection as the legally
qualified chemist and druggist is entitled to look for.
It may be hoped, therefore, that Mr. Andrews’ kindly
consideration for poor chemists may undergo a change in its
direction, and that he may be led to recognise in the new
bye-laws an appropriate means of giving effect to it.
The case of the apprentices north of the Tweed who have
to support themselves and earn their qualification fees, as
represented by Mr. MacEwan, naturally failed in Cambridge to
produce the desired effect, since such conditions are by no
means uncommon there. One of the apprentices present at
the meeting pointed out this fact, and suggested that the poor
fellows north of the Tweed had too much backbone to be
beaten by the demand for another five guineas, a result more
probable with candidates of a jelly-fish order which is not
common in Scotland. This youngster deserves credit for the
view he expressed, and it may be anticipated that, in his
future career as a pharmacist, he will be among those who
take a front seat.
But one of the most beneficial results to be looked for as
following from increase of the qualification fee, is the clearing
away of some portion at least of the encumbrance of rejected
candidates, which has become a disgrace to the calling, besides
being a source of serious detriment otherwise. Concurrently
with improvement in that direction, there would probably
be corresponding reduction in the amount received by the
Society, so that increase of the fee appears on this account to
be necessary. As regards the matter of financial requirements
the view expressed by Mr. Taplin and by Mr. Campkin
should commend itself to all registered chemists and to all
who aspire to obtain registration. The money required for
conducting the work done by the Society in its public capacity
must be provided by those seeking qualification and
desiring to participate in the advantages attaching to
registration. Whether the examinations pay is not the
question, for the qualification of a chemist and druggist
is not conferred as a matter of trade. There are other purposes
necessarily belonging to the administration of the Pharmacy
Act for the benefit of the trade at large, to which the private
means of the Society have hitherto been liberally applied,
and justice requires that all registered chemists should also
contribute as well as subscribers to the Society.
278
PHARMACEUTICAL JOURNAL.
[March 27, 1897.
AM NOTATIONS.
The Proposed New Bye-Laws apparently commend themselves
to the members and associates of the Pharmaceutical Society as a
whole, such disinterested criticisms as have been offered — and there
have been very little of any other kind — being in support of
modifications that have already been shown to be undesirable.
Suggestions that cannot be adopted without obtaining fresh
powers from the Legislature are obviously quite beside the mark in
the present discussion. London and Cambridge have declared
themselves unreservedly in favour of the proposed alterations,
Nottingham, Glasgow, and Plymouth are preparing to discuss them,
and will doubtless approve in an equally unmistakable manner.
Indeed, it is difficult to see that any body of chemists and drug¬
gists can reasonably take objection to the proposals of the
Pharmaceutical Council, which have been framed in the best
interests of the whole body and not of those connected with the
Society only. Criticism, as such, should not be objected to by any
governing body in a healthy condition ; but opposition to the policy
o' the Society, as interpreted by its Council, should not be based
on the assumption of a non-existent state of affairs.
A Huge Mythical Profit for the Society has been predicted,
amongst other errors, as it seems too readily to have been assumed in
certain quarters that the Society will enjoy a greatly augmented in¬
come if the proposed alterations in the bye-laws receive the stamp of
authority. If due allowance be made for certain inevitable re¬
sults of the change, it will be seen that the financial position is not
likely to be affected to anything like the extent that might be
imagined at first glance. The abolition of the Preliminary
examination will result in a considerable permanent loss, for
though the cost of the examination will be saved in each case,
there will be a large diminution in the number of registered
students. This will be unavoidable in the absence of powers to
enforce a three years’ interval between registration as a student
and qualification. Then, as to the qualifying examination, an
important and not the least useful effect of the increased
registration fee will be an appreciable reduction in the number of
those who come up only to fail to satisfy the examiners. When a
prospective candidate sits down to count the cost, and considers
that the expense attending failure is twice what it now is, it does
not require a very extensive acquaintance with human nature to
arrive at the conclusion that he will defer his attempt to secure
registration as a chemist and druggist, until he feels much more
certain of success than is common at the present time. And in
this way a greater benefit will be conferred on candidates than is
possible under any other circumstances short of a compulsory
curriculum of study.
The Broader the Earlier Education is, as so ably pointed out
in the Journal by Mr. E. Saville Peck, some eighteen months ago,
the better pharmacist is a youth likely to become. And to secure
the necessary breadth, it is essential that an advanced stage should
have been attained before the period of purely scholastic education
closes. By extending the range of subjects, a knowledge
of which shall be required of all candidates for registra¬
tion as students, and increasing the standard, the desirability
of passing the Preliminary examination before leaving
school will be rendered more evident, as shown by Mr. Peck.
In addition, those who have neither the intellectual capacity
nor the application required to pass the Minor will be more
thoroughly eliminated, and recognition of unfitness for a pharma¬
ceutical career will probably come much earlier than at present,
thus enabling the pharmaceutically unfit ‘ ‘ to turn their hand to
work more fitted for their abilities ” before it is too late
Finally, and a most cogent reason, having passed an examination
demanding a fairly high intellectual capacity, the would-be phar¬
macist will be less likely to stoop to unworthy tasks, or to serve
under an incapable principal.
The Pharmacy Acts seem to have as determined a foe in Judge
French as in one or two of the Scottish sheriffs. We had occasion
some time ago (see last volume, p. 388) to comment upon the evident
bias displayed by the same judge in a case where it was
clearly shown that public safety had been endangered . by
the sale of poisonous .rat-cake by an unregistered person.
Though the evidence left no loop-hole for escape from
the logical conclusion, the judge decided in favour of the
plaintiff most reluctantly, and practically subjected the Pharma¬
ceutical Society to a penalty. It may appear to the lay
mind that the proof of illegal sale of poison was fully as
clear in the case decided at Bow County Court on Monday ;
indeed, the answers of the defendant to interrogations admin¬
istered to him leave little room for doubt that he had been in
the habit of retailing poisons and ought to have been fined for so
doing in the present instance. But on this occasion the Society was
deprived even of the poor satisfaction of a disastrous victory for, in
the face of all the facts, Judge French gave judgment for the defen¬
dant, petulantly reproaching the Society meanwhile for perform¬
ing a public duty. Unfortunately, no opportunity is afforded of
entering an appeal against such judgments, however unsupported
they may be by facts, but if these displays of unwarranted pre¬
judice by judges and sheriffs continue it may become necessary for
a question on the subject to be asked in the House of Commons.
Otherwise, it is difficult to see how these individuals who set
themselves above the law can be kept in order.
Lime Cream and Glycerin, alleged to contain none of the
latter ingredient, though the maker says he put some in, is now
on its trial at Brentford Police Court. The formula of the prepara¬
tion resembles that recommended by Mr. Hyslop in this week’s
Journal, but if glycerin present to the extent of half a drachm in
eight ounces cannot be detected by public analysts, it is difficult to
see that safety lies in the direction indicated for the unnecessarily
harassed chemist and druggist. If the Somerset House chemists
also fail to detect the presence of added glycerin, the only
alternative will be to name the preparation “ Lime Cream,”
pure and simple, as suggested by Air. Hyslop. But if emulsi¬
fication is effected by the aid of liquor potass ic in place of solutio n
of lime, a method preferred by many, the problem will become
still more involved, for “ Lime Cream” and “ Cream” will be
equally debarred as names, and perhaps the only way out of
the difficulty will then be to decline to supply the public with
the preparation under any of the names they know it by. Which,
as Euclid observes, is absurd !
The Liquor Licensing Laws Commission has secured a huge mass
of evidence, the first volume containing which is an enormous Blue-
Book of nearly five hundred folio pages. Air. Bannister, of the
Government Laboratory, Somerset House, referred in the course
of his evidence to so-called “temperance drinks.” In one case
herb beer had been sold, at Nottingham, which contained.il per
cent, of alcohol, and “parsnip beer” had been found to contain
as much as 13*7 per cent., while a “blue ribbon drink” yielded
about 3 per cent, on examination. Other “temperance” drinks
were shown to be exhilarating enough in their way, ginger beer being
found to contain as much as 8| per cent, of proof spirit ; “medical
porter,” 7 per cent. ; orangeade and dandelion stout, 8 per cent.
each ; and ‘ ‘ botanic porter,” 6| per cent. So much for the ‘ ‘ temper-
March 27, 1897]
PHARMACEUTICAL JOURNAL.
279
ance ” side of the question. On the other hand, Mr. Bannister did
his best to remove some apprehensions that have afflicte 1 whisky
drinkers and others. In particular, he stated that the supposed
bad effect of fusel oil in spirits is much exaggerated, and claimed
that, in the small quantity in which it is found in whisky, it may
even promote digestion.. Neither new nor old spirit, he insisted, is
the especial cause of mischief to topers, but the absorption of
excessive quantities of the attractive fluids. Reverting to the
fusel oil question, the witness thought there was no doubt that
the equivalent of more fusel oil would be taken in eating half a
pound of pear drops than in drinking “a good lot” of Scotch
whisky.
New Testament Microbes have engaged the attention of Mr.
F. W. Richardson, consulting chemist to the Bradford Corpora¬
tion, who has published an interesting report on the subject, at
the request of the public authorities of Ripon. Two New Testa¬
ments which had been kissed in the Liberty and West Riding
Court by some 40,000 persons, during a period of sixty years, were
submitted to bacteriological examination, and seven species of
micro-organisms were detected. These consisted of moulds,
yeasts, and schizomycetes, the latter including various cocci and
bacilli. Although the germs found are not necessarily harmful,
yet there are conditions in which they might produce unpleasant
complications and, speaking as an expert, Mr. Richardson says he
would not like to kiss any surface upon which those microbes were
spread. If salivary germs, even leaving aside the possibilities of
their having originated from sore or wounded surfaces, could
thus be introduced into and upon the Testament by kissing, the
Yorkshire Post asks if it is not possible that other microbes, such
as those of diphtheria, scarlet fever, etc. , might similarly be left
there. The culture tubes containing the microbes and moulds
found in a living state in and on the books have been forwarded to
Mr. H. B. Rudd, pharmaceutical chemist, Ripon, in order that he
may exhibit them as an object lesson for the citizens.
The Geologists’ Association, London, has arranged an excur¬
sion to Chesham and Cowcroft on Saturday, April 3 ; one to
Aylesbury, Hartwell, and Stone, a week later ; and another to
Walmer, St. Margarets, Dover, Folkestone, and Romney Marsh,
during the Easter holiday, starting from Charing Cross on
Thursday, April 15, at 4.30 p.m., and arriving in town again on
the following Tuesday night. Subsequent excursions will be to
Cookham, Southboro’ and Tunbridge Wells, Chislehurst, Erith,
Cheltenham, Leighton, Merstham, Peterborough, Bishop’s Stort-
ford, and Edinburgh. This programme should tempt many to
join the Association, more particularly as special fares for the
excursions are quoted in many instances, and competent geologists
are to act as conductors in every case. Full particulars may be
obtained of Mr. H. W. Monckton, 10, King’s Bench Walk,
Temple, E.C.
The Chemists’ Assistants’ Association is about to sever its
connection of so many years’ standing with the premises in Great
Russell Street, and we are asked to state that the meeting
arranged for Thursday, April 1 (avert the omen !) will be held at
9, Queen’s Square, W.C. The programme for that evening will
include a discussion on the proposed new bye-laws of the Pharma¬
ceutical Society, in addition to the reading of short papers by
members. On the social side, the Association appears to supply
a want amongst its members and their friends, the
Cinderella dances held during the session having proved
extremely successful. The last of the prearranged series
takes place as we go to press, but Mr. C. Morley, President
of the Association, writes to say that, in response to numerous
requests, an additional but unofficial dance on similar lines will be
held on Tuesday, April 6, at the Dorset Hall, Portman Rooms.
Tickets (2.9. 6 d. each) may be obtained from Mr. A. R. Melhuish,
116, St. John’s Street, E.C., and as all profits will be devot' d to
the Benevolent Fund, it is hoped that thgre may be a large
attendance.
The Pharmaceutical Poet of the North, Mr. Alexander Laing,
is favoured with a corner of the Kelso Mail for March 17, where
he pours out some not unattractive rhyming strains addressed to
“ The Fisher Maiden.” Another rhymester’s effort, which
should appeal to our readers, and especially to such as have not
yet forgotten all they were taught of the Latin tongue, is an ode
‘ ‘ To Lycoris ” (Liquorice) which appears in the Granta, and a
few lines of which are here given
Nigra, dulcis et viscosa
Quantum amo te, Lycoris !
Quurn magister (pende ilium ! )
Tergum vertit. pro momento
Manus mea ad os fugit
Portans globulos superbos ;
Furtim sugo, sugo semper,
Tanquam veteres cothurnos (boots)
Tanquam domum super ignem
Dico sugo tanquam flammas !
Ignoro quod dicit iste
Paedagogus semi-caecus.
Pe ponderibus et mensuris
Flatus sim si euro floccum !
German Thermometers were eulogised by Professor Riicker
when a deputation recently waited upon Lord Salisbury, in the
hope of persuading him to allow a few individuals — who, of course,
have only the good of “British science” at heart — to enjoy the
fingering of a fairly large sum of public money. The learned pro¬
fessor, with a fine disregard of facts, ventured to assert that no
high-class mercurial thermometers are now made in England, but
that they are made in Germany. In Tuesday’s Times , however, Mr.
J. J. Hicks, of Hatton Garden, whose absence in Australia has pre¬
vented him dealing with the matter earlier, states that this is the re¬
verse of the truth, as such thermometers are made here and always
have been. The Kew authorities, according to Professor Rucker, send
their standard thermometers to France or Germany to be re-tested,
but Mr. Hicks thinks this is incredible, as better means exist for
testing thermometers at Kew than anywhere abroad, and the workers
there have had far more experience and practice. He then pro¬
ceeds to carry war into the enemy’s territory by asserting that
nine-tenths of the German thermometers made are most inaccurate,
some in his possession being from ten to eighteen degrees out in
some part of their scales — “they are what we in the trade call
cheap, but dear at any price.” Many users of thermometers, and
especially clinical thermometers, are in a position to confirm this
statement, and it is satisfactory to note that some British manufac¬
turers are yet in a position to “ give points” to their foreign rivals.
A Knowledge of the Odds may or may not be accompanied
by evils, but the following incident commended by the Lancet to
the notice of Mr. Hawke, as another instance of the supposed evils
of such knowledge, is too good to be lost in our contemporary’s
heavily laden pages. Scene : The ward of a metropolitan hospital ;
in one bed is lying a member of the sporting fraternity ; to him
enter a surgeon, attended by fifteen eager and obsequious dressers.
Surgeon, to the dresser of the case, after an able and exhaustive
account of the symptoms : “ Now, Mr. Smith, would you operate
on this case?” Mr. Smith (dresser): “No, sir, I should not.”
“ And you, and you, and you ?” indicating the others. Unanimous
negative. “Well, gentlemen, you are all quite wrong,” says the
surgeon, with conscious pride, “I intend to operate.” Voice from
the bed : “ No you don’t, gov’nor ! Fifteen to one agin it — no
chaunce. ’Ere, Isay, miss, give me my clothes; I’m orf.” And
yet, hospitals are usually regarded as places of sadness, and the
last spots in the world to look for anything humorous.
280
PHARMACEUTICAL JOURNAL.
[Maech 27, 1897
JWEETIflGS Op SCIENTIFIC SOCIETIES
— - — ♦ -
Chemical Society, Thursday, March 4. — Mr. A. G. Vernon
Harcourt, F.R.S., President, in the chair. — Everybody of note in
chemical circles seemed to be at this meeting. Dr. Scott, of the Davy-
Earaday Research Laboratory, was probably the attraction for a
great many ; at all events, he had the satisfaction of speaking to
one of the largest audiences of the session. — The Secretary first
of all announced that Professor Ramsay had been nominated as
President of the Society, in succession to Mr. Harcourt. — Dr.
Collie rose to say that Professor Ramsay had been nominated
without his knowledge or permission. — Mr. Spiller had a com¬
plaint to make. His last copy of the ‘ Proceedings ’ had arrived in
a state unfit for binding. It was, he said, what is technically called
a “waster.”— Mr. David Howard then rose and said that Mr.
Spiller was lucky in getting anything at all. He had not yet
received the January number of the ‘ Journal.’ — Dr. Kipping
suggested that as there was to be a contested election it might be
desirable to hasten the publication of the ‘Proceedings.’ — The
President informed Dr. Kipping that the attention of the Council
had been drawn to the matter, and Professor Thompson assured Mr.
Spiller that the ‘ Proceedings ’ would be forwarded in good order
in future. — The first paper was by Dr. Alex. Scott, M.A., D.Sc.,
On the Atomic Weight of Carbon.
This was mainly a critical paper. The author reviewed the
work of Dumas, Stas, Marchand, and others, and although he
points out some gross errors in the calculations of Stas and the
others, he says that we may still consider that the atomic weight
of carbon is twelve. He had prepared his carbon from sodium
oxalate in a state of great purity, being perfectly free from
hydrogen. In answer to a question by Mr. C. E. Groves as to
how much carbon he had obtained from the oxalate, Dr. Scott said
that he had obtained 4 grammes from 160 grammes of the salt.
- — Mr. Blount inquired if the carbon thus obtained was absolutely
free from mineral matter, but Dr. Scott did not seem ready to
guarantee this. — As the discussion at this point was rapidly
becoming conversational, the President announced that Dr. Scott
would now read his other paper — -
On a New Series of Mixed Sulphates of the Vitriol Group.
The results embodied in this paper are the outcome of certain
observations made during the examination of students. The key-note
of the whole thing is found in the fact that when strong sulphuric
acid is added gradually and in equal volume to a hot saturated
solution of ferrous and cupric sulphates, a bright red crystalline
precipitate is formed, having the composition —
Cu . 18
Fe . 40
SOj . 58
HaO . 58
Some curious results are obtained according to the proportions in
which the various substances are present. In certain cases there is too
much base for the sulphuric acid. In answer to a request by the
President to write the formula for the salt, Dr. Scott replied that
at present he was not able to do so. Other double salts or mixed
sulphates prepared on the same lines are copper-nickel, copper-
zinc, which is a white salt, and copper-cobalt which is also white,
and contains 13 per cent, copper and 20 per cent, cobalt; also
cobalt-nickel and chromous-zinc. The last-named salt contains
11 per cent, chromium, and 23 per cent, zinc, and is prepared
from the chromium acetate. The green colour of the salt is due
to the presence of chromic salt. Many other salts were prepared
and shown on the table. — Mr. Spiller was the first to speak,
saying that he had gone over the same ground ten years ago, but
not quite so far as Dr. Scott had gone. The result of his work
was communicated to the British Association. — The President
supposed that the action of the sulphuric acid was simply that of
dehydration, just the same as when sulphuric acid was added to
copper sulphate itself. The sulphate in this case, as in all the
salts prepared by Dr. Scott, contained only a single molecule of
water. Dr. Scott’s preparations, he thought, were really double
salts of the same type. — Dr. Scott briefly replied, and the
President announced that an important communication had been
sent by Dr. W. H. Perkin, and would be read by Dr. Kipping.
The title of this paper was —
The Synthesis of Camphoronic Acid,
which Dr. Kipping said was a mod,est title, and one that gave no
idea of the tremendous amount of work involved. Hitherto this
chemical problem has been attacked by breaking the camphor
molecule to pieces. Dr. Perkin’s object, however, has been to
build it up, or in other words, to arrive at the composition of cam-
hor by synthesis. Dr. Perkin started with isobutyric acid, which
e converted into the monobromo derivative, and then into ethyl-
aceto-acetate, finally producing a body which he has conclusively
roved to be camphoronic acid, C10H16O6. The synthetical acid
as the same composition as that prepared from camphor, the same
melting-point, and the same reactions. He thus proves that
Bredt’s formula is right. Dr. Kipping said it was a matter of
congratulation that the synthesis had been done in England. It
was the most important step in advance that had been made for a
long time. Dr. Kipping here read a letter that had been handed
to him earlier in the evening from Dr. Perkin, describing another
reaction in further corroboration of his work. This latest achieve¬
ment by Dr. Perkin seems to have fallen like a veritable bomb into
the “camphor” camp, and no one replied to the President’s invita¬
tion to speak.
Linnean Society of London, Thursday, March 4. — Dr.
A. Gunther, F.R.S., President, in the chair.- — Mr. W. Carru-
thers, F.R.S., exhibited, with the aid of lantern-slides, a series of —
Portraits of Linnasus,
and gave some account of the history of each. In the
course of a tour which he had made in Sweden and Hol¬
land, he had been fortunate enough not only to see the
original paintings, but also to obtain photographs of them, so
that he was now able to exhibit exact copies. Putting aside
“supposed portraits,” and such as might be termed “fancy
portraits” having no claim to authenticity, he had satisfied
himself of the existence of eight that were certainly painted
or drawn from life, and had been copied more or less
frequently by different engravers. The earliest of these was
painted by Hoffman in 1737, while Linmeus was working for his
patron Cliffort at Hartecamp, and represents him at the age of
thirty in the picturesque dress in which he travelled through Lap-
land. Of the next portrait, an engraving by Ehrensverd in 1740,
no original is known to exist. In 1747, at the age of forty, two
pencil sketches of Linnasus, one being a full length, were made by
Rehn ; and five years later a beautiful pastel was executed by Lund-
berg. Scheffel in 1755 painted him at the age of forty-eight ; and
this portrait is preserved at Hammarby in the house of Linnaeus,
now public property under the care of Professor Fries, of
Upsala. Then came the medallion by Inlander, executed
in 1773, of which a copy (one of three) is in possession of this Society.
The following year, when Linnaeus was sixty-seven years of age,
his portrait was painted by Krafft, and was placed originally in
the Medical College of Stockholm, of which Linnaeus was one of
the founders. It was supposed to be lost, but had been removed
to the Royal Academy of Sciences in Stockholm, where Mr.
Carruthers discovered it. The latest portrait was that by
Roslin, painted in 1775, when Linnaeus was in his sixty-eighth year.
A fine copy of this by Pasch, presented to Sir Joseph Banks, and
given by him to Robert Brown, now hangs in the Society’s Library
Dr. W. B. Benham then read a paper on some
New Species of Earthworms
belonging to the genus Perichceta from New Britain and
elsewhere, with remarks on certain diagnostic characters of
the genus. After pointing out the characters of Perichceta,
and the various structures available for the determination of
species, the author gave an account of five new forms which
had been received from Borneo, Singapore, the Philippines,
and New Britain. Those from the last-named island had
been collected by Dr. A. Willey during his voyage to the
South Sea Islands in quest of the eggs of Nautilus. No earth¬
worms had been previously recorded from New Britain. Dr.
Benham recalled the fact that in 1891 he had proposed the name
malamaniensis for a species of Perichceta from the Philippine
Islands without giving a diagnosis of it, and that he now supplied.
—On behalf of Mr. W. G. P. Ellis, Demonstrator in Botany at
the University Botanical Laboratory, Cambridge, the Secretary
gave the substance of a paper —
On a Trichoderma Parasitic on Pellia Epiphylla.
It was directed to an investigation of a form of disease
in liverworts, which the author had noticed in the Botanic
Garden, Cambridge. The chief point to be determined was
March 27, 1897]
PHARMACEUTICAL JOURNAL.
281
whether the fungus had lived as a saprophyte on the dead thallus,
and thence extended as a parasite into the living tissues ; or
whether the appearance was associated with the fact that rhizoids
were not yet developed at the apical parts by which the
fungus might enter. The author found that the thallus of
Pellia epiphylla was affected by a disease evidently epidemic in
nature, caused by a fungus whose septate mycelium was found in
the tissues of the host. On isolation it was seen to be the conidial
form of an Ascomycete, and from its structure and conidia,
and from its life-history, so far as it could be made out, it appeared
to be similar to, if not identical with, the Trichoderma phase of
Hypocrea, but no resting stage had yet been found. It was culti¬
vated on nutrient media, and spores from a pure culture when
applied to healthy thallus produced in it a disease like that of the
original thallus. By means of sections the direct infection of the
host by its upper surface was followed out, and the parasitic nature
of the fungus was established.
Botanical Society of Edinburgh, Thursday, March 11. —
Mr. R. A. Robertson, M.A., B.Sc., read a paper on a new method
for the
Photo-micrography of Opaque Stem Sections.
One difficulty in making photo-micrographs from recent or fossil
stem sections is the difficulty of getting a sufficiently large section
to bring out diagnostic features. Another difficulty is that it is
a difficult process to cut and grind and polish large sections
of fossils for photography by transmitted light. A further
difficulty is that one cannot always get permission to make sections
of valuable museum specimens of recent and fossil woods. Mr.
Robertson has found that by directly photographing the surface by
means of a micro-photographic apparatus, excellent pictures giving
all necessary histological details of the tissues, can be readily
obtained. The recent wood surfaces are planed with a steel plane,
and if at all rough the surface is slightly wetted. Very careful
focussing is necessary so as to get equal illumination. An opaque
focussing-plate should be used for rough adjustment, but the final
focussing must be done with a clear glass plate. The illumination
was by means of a magnesium ribbon fed through a fixed tube and
placed at an angle of about 45° and a distance of about 10 or 12
inches from the surface to be photographed. An exposure of
about forty seconds with Ilford plates gave the best results. The
pho. o-micrographs taken gave an area of the wood of about 3
inches square.
THE WORLD Op PflflRflflflCY.
- + -
BUSINESS MEETINGS.
Cambridge Pharmaceutical Association, Friday, March
19. — Mr. Alderman Deck, F.C.S., President, in the chair. — The
topic for discussion was the proposed new bye-laws of the Pharma¬
ceutical Society. The subject had aroused a considerable amount of
interest, there being present Messrs. E. S. Peck and Milling
(Secretaries), Herbert F. Cook, C. S. Addison, E. J. Dobson,
L. A. J. Hutchin, L. White, A. S. Campkin, J.P., F. S. Campkin,
B. S. Campkin, C. Male, A. P. Barker, Coupland, Turner, and
others. There were also present Dr. Paul, Pharmaceutical J ournal ;
Mr. Cantwell, British and Colonial Druggist ; and Mr. P. MacEwan,
Chemist and Druggist. — The Chairman intimated that he had
received a letter from Mr. H. J. Parsons, who apologised for not
being able to be present. — He then called upon Mr. E. Saville
Peck, B.A., who, in introducing for discussion the
Proposed New Bye-Laws,
classified them under two heads (1) The Substitution of the Present
Preliminary Examination by a Certificate from one of the approved
Examining Bodies, and (2) The Raising of the Qualifying
Fee from £5 5s. to £10 10s. After quoting the proposed
bye-laws, eleven and seventeen (see Pharmaceutical Journal,
p. 210), he said that for several years there had been
a growing opinion that the First examination should be made a
more severe test of the ability of the young aspirant of pharmacy.
He considered the Council had done wisely in deciding to cease
holding the Preliminary examination, and instead to accept the
certificates of those bodies which exist for the sole purpose of
examining in arts ; such as Cambridge and Oxford Locals, College
of Preceptors, etc. He then referred to a letter which appeared
in the Pharmaceutical Journal for August 24, 1895, in which
he advocated a higher standard of education', and making the
the Preliminary examination a compulsory condition of apprentice- *
ship, or at least fixing an interval between it and the qualifying ex¬
amination. Unfortunately the latter plan would require an Act of
Parliament and, failing that, the proposed new bye-law appeared
to be the next best thing, as it would perhaps deter many insuffi¬
ciently educated youths from entering the craft, besides
making the parents of lads desiring to become pharmaceutical
apprentices more careful in placing their sons in the trade
without considering their fitness to meet subsequent requirements.
As to the question of the higher fee, there might not be the same
unanimity of feeling as with regard to the Preliminary
examination. The ten guinea fee must, however, be looked upon
as not only consisting of a fee to qualify one to practise as a chemist
and druggist, but also the fact must be taken into consideration
that it meant registration for life, and he did not think £10 10s.
was an exorbitant sum for that purpose. He did not agree with
those who consider that if the fee is raised from five to ten
guineas each person who qualifies should become an associate
or member of the Society without further payment. Compulsory
membership might be a disadvantage, as the members so obtained
would probably cease to take an active interest in the Society. He
asked those apprentices and assistants present who had not
qualified to remember that the more difficult and more ex¬
pensive the qualification is, the fewer men they would be likely
to have to compete with in after life. The cheaper they valued
the qualification, the cheaper they themselves would be valued
in their after career. He thought it useless for them to compete
with each other on the score of prices, because he did not believe
they could persuade people to take more physic simply because it
was cheap. Their efforts should be in the direction of keeping up
prices, and the only way to accomplish that object would be by
keeping men out of pharmacy who would be willing to work for
inadequate remuneration. This end would sooner be reached by
the adoption of measures similar to those proposed by the Pharma¬
ceutical Society. Therefore he had great pleasure, and he could
almost say pride, in moving the following resolution : —
“ That this meeting of the members of the Cambridge Pharmaceutical Associa¬
tion and other members of the trade in Cambridge, convened for the purpose
of discussing the proposed new bye-laws of the Pharmaceutical Society,
wishes to express cordial approbation of the efforts of the Pharmaceutical
Society to advance the education and interests of chemists generally.”
Mr. Addison seconded the resolution. — Mr. Peter MacEwan was
then asked by the Chairman to state the case for the opposition.
He commenced by expressing the regret of his chief, Mr. Wootton,
that he would not be able to be present, as was his intention.
With regard to the Preliminary examination, he thought the move¬
ment would meet with the general approval of the thinking por¬
tion of the trade. He regretted the legal inability to make the
examination compulsory prior to a lad entering a pharmacy ; also
that the Council had not deferred the proposal until after the
General Medical Council decided what subjects are to be embodied
in its future Preliminary, as he thought the student of pharmacy
who afterwards wished to enter the medical profession would be
placed at a disadvantage, because he believed the Medical Pre¬
liminary would be a much more stringent one than that
proposed by the Pharmaceutical Council. Mr. MacEwan thought
The Increased Minor Fee
would probably not affect English students very severely,
as their fees were generally paid by their parents, but
north of the Tweed, as a rule, students had to support them¬
selves, and speaking from personal experience, he thought
the increased fee of £5 5s. would press very hardly on them,
and in some cases almost “ break their backs.” Therefore
he considered the fees should not be raised unless it was absolutely
necessary for the carrying on of the examinations and the cost of
registration. For this purpose he contended it was not necessary
to raise the fees, seeing that from 1868 to the present time the
present fees had been ample. He then dwelt at considerable
length on the dual functions of the Pharmaceutical Society, and
endeavoured to show that the income from examinations com¬
pletely covered all expenses connected therewith, but that the
expenditure on purely Society business, such as the School,
282
PHARMACEUTICAL JOURNAL.
[March 27, 1897.
Library, Museum, Journal, etc., since 1887 had been much more
than the income derived from the subscriptions of members, etc.
Hence he contended that the demand for the extra £5 5.s. as a regis¬
tration fee was not based upon tangible or just grounds; but was
to assist the Council in meeting the private expenses of the Society. —
A point of order being raised by the Secretary, Mr. Peck, the Chair¬
man ruled that the financial position of the Society had no bearing
on the matter under discussion, i. e. , the proposed new bye-laws. —
Mr. MacEwan submitted to the ruling of the Chairman, and after
a few more remarks resumed his seat. — Dr. B. H. Paul, on being
asked to speak, explained that he was there merely to listen to the
discussion on a very important subject. He might have had
something to say which might perhaps have sufficed to convert
Mr. MacEwan or Mr. Wootton, but he was under the impression
they were not disposed to be converted, and therefore it would be
superfluous to say anything. Moreover, asan officerof the Pharmaceu¬
tical Society, he did not think it would be appropriate for him to take
part in the discussion. — Mr. Cantwell, of the British and Colonial
Druggist, explained his presence by stating that circumstances
had arisen under which it was supposed that a personal ques¬
tion between the journals was imported into the discussion
of the proposed new bye-laws, and he wished to say that
as far as his journal was concerned he had simply pointed out a
possible effect of the proposed changes in the bye-laws. The
further consideration of the matter he desired to leave to the
members of the Society on the one hand, and to those who
might be affected by the Society’s proposals on the other.
He raised no personal question whatever in regard to the
financial position of the Pharmaceutical Journal, or as to the
expenditure of the Society. His journal was accustomed to com¬
petition, but the competition experienced from the
‘Pharmaceutical Journal’
had always been of a fair character, and there was no
reason why they should bring any personal considerations into the
subject now under discussion by the various Associations. — Mr. A.
S. Campkin, J.P. , was inclined to regret that the Chairman
had ruled Mr. MacEwan to be out of order in bringing into the
discussion the question of finance. He thought the Society had
nothing to fear from criticism. Had they gone into the whole ques¬
tion which had arisen in the journals during the past three weeks he
believed any criticisms of Mr. MacEwan with respect to the Society
or the Pharmaceutical Journal would have been ably answered,
and he had no doubt satisfactorily answered by Dr. Paul. With
regard to the Preliminary examination he thought everyone was
unanimously agreed that the alteration was a good one. He
believed that too great care could not be taken in the training of
young men for chemists and druggists, and that* parents should see
that their sons were properly equipped before they entered upon
their apprenticeship. It could not be too emphatically stated that
masters should insist on the Preliminary or its equivalent being
passed before taking upon themselves the responsibility of training
apprentices. As to the question of raising the fees, he thought
Mr. MacEwan had fairly put the case for those on the other side
of the Tweed, and assuming that they were all agreed that the
fees should be raised, he was of opinion there should be some
proviso which would be perfectly just and equitable, whereby
those already in the business who had not passed the qualifying
examination should be allowed to come under the old bye-laws, and
that the new bye-laws should only apply to future entrants.
He hoped this matter would receive consideration at the hands
of the Council. Without discussing the financial position of
the Society, Mr. Campkin thought that in any case the
Pharmaceutical Society Must Continue to Exist,
whatever happened and whatever might be the actual financial
condition. It was the duty of every chemist to support its en¬
deavours to carry out the dual functions referred to by Mr.
MacEwan. He believed the Pharmaceutical Society, however
imperfect it might be, possesses the germs of an organisation
which might easily be brought to a state of perfection, and he
urged upon all present to give their hearty adhesion to the Society.
— Mr. Hutchin quite agreed with the proposal to raise the
standard of the Preliminary examination. He did not see why a
higher standard should be necessary for a veterinary surgeon than
that required for a chemist. He believed it was largely due to the
low standard in the past that at the present time pharmacy was
brought into disrepute, either by cutting or by the practice of
counter prescribing. With regard to the question of the £10 10s.
fee, he thought if any change is brought about it should certainly
not come into force before 1900, which would give the Minor
students time to pass their examination, and the extra fee should
not be demanded again if they came up a second time for exami¬
nation. He considered that £10 10s. should be amply sufficient
for the first fee, and then three guineas for the second attempt.
He thought, however, it would be better to charge £5 as an exami¬
nation fee and £5 as a registration fee when the candidate had
passed the examination. With regard to
The Dual Position of the Society
referred to that night, he thought it was a position rather
difficult to define. It was a dual position, which resembled some¬
what the position of the right hand towards the left, and the left
towards the right. The Society held the position of examining
body to the trade, and it had the carrying out of the Pharmacy
Act as in the various prosecutions which it had so successfully
carried on of late. The trade looked to it to act in the general
interest of all, and it could not do so unless it had the sinews of
war wherewith to fight. They could not have compulsory member¬
ship except by a separate Act of Parliament, but if the Society
could get more sinews of war by raising the fees, he thought they
should be raised, because at present things were in a most unfair
condition, inasmuch as all members of the trade share in the
benefits resulting from the Society’s work. It was only necessary to
refer to the Pharmaceutical Journal or to the Chemist and Druggist
that week to see how prosecutions were taken up by the Pharma¬
ceutical Society against those who damaged the trade generally.
By an addition to its income the Society would be in a better
position to maintain the position of those in the trade. Reference
had been made to the rival journals; it seemed to him that if, at a
comparatively small cost, the Pharmaceutical Journal could be
issued to the members of the Society, the trade generally bene¬
fited, because many would not pay their guinea to the Society
unless they got something tangible back again, and the result
was that after issuing the Journal the Society had 16s. from
each member, which it used for the benefit of the trade. He thought
the yearly subscription was one of the best investments it was
possible to make, and he believed that the Society would benefit
the trade more in years to come than even at present. —
Mr. H. F. Cook heartily concurred with the proposal anent the
Preliminary examination, but with regard to the second proposi¬
tion of instituting a £10 10s. instead of a £5 5s. fee he was inclined
to agree with Mr. MacEwan in thinking that it would deter many
young fellows from entering the profession. — Mr. C. S. Addison
thought the proposed abolition of the present Preliminary exam¬
ination and the substitution of a higher standard to be a step in
the right direction, but was of opinion it should be made stiller
and take in some scientific subjects, such as chemistry and
botany. He was greatly in favour of an Act which would make it
compulsory that the Preliminary should be passed before appren¬
ticeship is entered upon. He found that
The Greatest Grumblers
were those who had entered the trade and, after spending the best
part of their lives in it, had, from one reason or another, been
unable to qualify themselves. Their failure was, in their
opinion, not due to themselves, but the Society was to
blame. Had they been called upon to pass a stiff Pre¬
liminary before entering the trade, in all probability they
would have gone into some other branch of business, and
pharmacists would not now have had them as competitors.
He thought the £10 10-s\ fee should be made to include registration
and membership or associateship of the Society. He believed
that would require an Act of Parliament, but if it could be done
and all registered men made members they would probably have a
better opinion of the Society if they had something at stake. They
would have the Journal, and would find out in other ways that the
Society was doing something for them. Then if they were not
satisfied it would be their own fault, and they could not blame any¬
body else for their own misdeeds. He should like to see the fees if
anything higher than those proposed. In his opinion they should be
£3 3s. for the expenses of the examination and £10 10s. to pay on
being registered. He hoped that if the Council did make a change
in the regulations it would make them as thorough as it could.
Mr. Addison expressed his regret that an attack had been
made on the Council by the Chemist and Druggist in a
recent issue, but Mr. Cook objected on a point of order. — The
Chairman was much in favour of a higher standard for the
Preliminary. He mentioned the fact that he took his diploma
in 1853, and had been a member of the Society for forty- three years,
March 27, 1897.]
PHARMACEUTICAL JOURNAL
283
and sometimes he was twitted by the remark that he would not be
able to pass examinations now, but he thought, given a little time to
look up the subjects, he should not take a bad place. With regard
to the £10 10s. fee, he thought it ought to be raised to that sum,
as it would ensue some substantial support to the Society. He
did not like to see so many chemists cutting off their connection with
the Society after passing through the Minor, although they
still continued to reap-the benefits derived from it. — Mr. Turner,
referring to the remarks of Mr. MacEwan, said there were many
young fellows this side of the Tweed who had passed their
examinations and had paid for themselves entirely, and he did not
think they would have gone under for another “fiver.” With
regard to the “poor” fellows
North of the Tweed,
he thought another £5 5s. would not “ break their backs” entirely,
even if they had to work a little harder and save a little more. — Mr.
White had very great pleasure in supporting the Pharmaceutical
Society in their endeavour to reorganise the Preliminary examina¬
tion. The examinations must advance with the times. With
regard to the increased fee, that came more or less as a shock, but
he thought they should put every confidence in the authorities at
Bloomsbury Square. He had no doubt they had well considered
the question before offering the proposal to the general body ; he
therefore had great pleasure in supporting the Council in its pro¬
posals, and, he thought when they were carried out everybody
would appreciate them. — Mr. Peck briefly replied to the different
speakers, and the resolution was then put to the meeting and
carried without a dissentient vote. — Dr. Paul, in a few appropriate
words, expressed his thanks and those of his comrades of the press
for the courteous invitation given to them by the Association to
be present at the discussion, and the meeting then concluded.
Chemists’ Assistants’ Association, Thursday, March 18.
— Mr. Charles Morley, President, in the chair. — Mr. N. H.
Martin introduced for consideration the subject of
Pharmacy, Some of its Dangers and Duties.
At the outset, Mr. Martin expressed surprise at the way in which
he had frequently been misinterpreted in the past. His only
object at any time had been the good of pharmacy, of which he had
always held a high ideal from his earliest connection with it. It
was to the professional side that pharmacy must aspire if
it was to share with medicine its duties and responsibilities.
By the business conduct of such men as Allen, Bell, Deane,
Hanbury, Schacht, Brady, and others, pharmacy had during
the past fifty years built up a solid claim to the respect
and confidence of the medical profession and of the public,
and it was because of the real danger there is of forfeiting that
confidence, the speaker viewed with anxiety some of the practices
of the pharmacists of to-day. The makers of so-called “patent”
medicines are, on the one hand, seeking a closer alliance with
pharmacy, and on the other accusing pharmacists in advertise¬
ments of dishonest acts of substitution. With respect to adver¬
tising in connection with patent medicines, when a pharmaceutical
chemist lends his window for a pantomimic display of one of the
lower animals administering medicine to another, or when he
accepts an invitation to place a ‘ ‘ fetching ” lay figure which moves
its head, winks its eyes, and imparts information concerning a
medicinal preparation to the passing crowd, he would do well to
ask himself whether he is not only seriously endangering
his own reputation as an educated man, but impairing
pharmacy in the respect of the community. In handling
these proprietary preparations the pharmacist’s education,
training, and legal qualification do not give him a single
advantage over any boy or girl who can read the name of the
article. Moreover, it would be a matter of supreme indifference
to most makers of proprietary medicines whether their goods
reached the public by the hands of a pharmacist or a grocer, but
for the fact that he can make use of the reputation which pharmacy
has in the estimation of the public, and one local chemist is of
more value to him in giving an appearance of truth to his state¬
ments than half a dozen other tradesmen. The only reasonable
attitude for the pharmacist to adopt towards such medicines is one
of agnosticism. “ I do not know ” is the best answer the pharmacist
can give to all questions concerning the merits or demerits of such
preparations. With reference to the accusations that pharmacists
imitate these wonderful medicines and dishonestly supply
substitutes for them, the law deals very effectually with purveyors
of even “colourable imitations,” but with regard to substitution
no man, in common honesty, has the right to substitute the pills of
Smith for those of Jones, nor, knowing nothing about either, has
he fhe moral right to endeavour to persuade his customer to
accept those of Jones, on the ground that his pecuniary interests
are protected with him while they are not so with Smith. The
pharmacist, however, has the moral and legal right to use his
knowledge and training in the service of his customers, and it is
his duty on every occasion to substitute knowledge for ignorance,
and truth for falsehood. Another danger to pharmacy, far greater
than that of proprietary medicines, is connected with the
substances which in various guises it is sought to thrust
upon pharmacy through the medium of the medical profession.
Medicine and pharmacy are founded upon sciences which have been
built up by the discoveries and industry of scientists, and it is
the pride of both to think that anatomy, physiology, chemistry and
botany have passed through the empirical stages inseparable from
the beginnings of knowledge and have reached the stage when facts
can be compared and classified, and a proper position in the
system be assigned to each new fact. All precise knowledge must
proceed and be accumulated in that manner, and to conceive of the
immense number of scientific facts which are known to-day being
at the mercy of commercially interested individuals for their names
would be to imagine a veritable chaos of scientific nomenclature.
Commercially no objection can be advanced to a man who has
spent time and money in improving a substance, adopting
and protecting a brand to distinguish his own manufacture.
Scientifically, however, and for the purposes of medicine, it may be a
source of danger. In this way medicine and pharmacy may be
encumbered by twenty names for the same substance, all equally
meaningless and unscientific. Some of the names are made sug¬
gestive of the connection of the substance with some fashionable
complaint, such as “ migrainine,” “ influenzin,” “ antisudorin,”
etc. The “therapeutically active ingredients” of “influenzin”
are said to be “ phenacetin, caffeine, quinine, salicylate, and
sodium chloride,” while the composition of “antisudorin” is
“boric, citric, and salicylic acids, borax, glycerin, alcohol, dis¬
tilled water, and several ethers.” These preparations are degrading
to both medicine and pharmacy. A second kind of trivial names
is obtained by taking some well-known class of preparations, such
as infusions or tinctures, for distinguishing particular makes by
such words as “ infusionoid ” or “ tincturoid,” which are regis¬
tered as a brand or trade mark. Commercially there may be no
objection to this,- but when under the cloak of such the attempt
is made to deprive pharmacy of its right to make the things them¬
selves under their own names, the danger to pharmacy is a real one,
and it is increasing year by year. Pharmacy may be held to be
midway between a profession and a trade, and it has the oppor¬
tunity of reaping many of the advantages pertaining to both. This
position, however, exposes it to temptations peculiarly its own, for
while as a trade it is allowed to make use of various methods of
advertising, yet it is restrained on its professional side from
indulging in the exaggeration, which forms the key-note of modern
sensational methods of business. In conclusion, young pharma¬
cists should be loyal to the best traditions of pharmacy, and not be
tempted by the prospect of present gain to sacrifice their inde¬
pendence and self-respect, and the prospect of gaining the respect
of others. They must have faith in their principles, and adhere
to them through good and evil report, and they might
rest assured that pharmacy would then be respected in them,
and they would receive from the public remuneration adequate
to their needs.
Aberdeen Junior Chemists’ Association, Friday, March
19. — Mr. Leslie in the chair. — The Treasurer’s report was sub¬
mitted, and showed a very favourable balance. The Secretary’s
report followed, giving a brief sketch of the work done during the
session, which showed that the Association had been most success¬
ful in every way. The President then awarded the prizes to the
successful competitors for the Association’s prizes, placing Mr. C.
Philip first with a Squire’s ‘ Companion’ ; Mr. A. Fowlie second
with a Newth’s ‘ Chemistry’ ; and Mr. Farquhar third with a
Green’s ‘ Botany.’ The retiring Committee, who have worked so
enthusiastically for the Association’s success, have been photo¬
graphed (by Messrs. Hardie and Co. ) in a group, and the original
picture will be presented to the Senior Chemists’ Association. The
following office-bearers were then elected for next session : — Mr.
W. Bremner, President ; Mr. W. Bisset, Vice-President ; Mr. M.
K. Watts, Secretary ; Mr. P. Tavendale, Treasurer ; and the
members of Committee are Messrs. Bremner, Bisset, Booth,
284
PHARMACEUTICAL JOURNAL.
[March 27, 1897
Farquhar, F. Milne, P. D. Milne, Murray, Scorgie, Sutherland,
Tavendale, and Watt. Mr. R. Leslie was appointed Hon. Presi¬
dent, and Mr. C. Forbes Hon. Vice-President.
Glasgow and West of Scotland Pharmaceutical
Association, Thursday, March 18. — Mr. W. L. Currie, Presi¬
dent, in the chair. — The President referred to the recent pharmacy
prosecutions in the West of Scotland. He said most of those
present no doubt knew about the prosecutions which had taken
place in Glasgow and the surrounding district, in connection with the
sale, by unqualified assistants, of poisons and proprietary articles
containing poison ; but all of them might not have noticed the
widely divergent views held and expressed by the different sheriffs
who heard the cases. That such difference of opinion should exist
in the legal mind as to the objects and purposes of the Pharmacy
Acts was a great misfortune ; but when the difference is such that a
presiding judge feels compelled to utter strictures against a repre¬
sentative public body, and to impute to it motives of questionable
dealing, then it is high time something should be done to vindi¬
cate the position of the Society, or at all events to have the Act of
Parliament so amended as to leave no manner of doubt in the legal
mind as to what the Legislature intends to be the true
interpretation of such Act. In the cases tried at the Glasgow
Sheriff Court, the presiding Sheriff had evidently no difficulty in
making up his mind as to the course he should adopt ; but in
the cases tried at Airdrie before Sheriff Mair, the latter, while
finding the accused guilty, admitted that he did so only in
deference to previous decisions in the higher courts. Evidently
Sheriff Mair was in doubt as to what the Act really means, and to
get over the difficulty he broke into a tirade against the Pharmaceu¬
tical Society and the Pharmacy Act, imputing to the prosecuting
body motives of anything but straightforward dealing, and finishing
up by inflicting a small fine to show his contempt. Such remarks
falling from judicial lips were not calculated to ensure the carrying
out of law and order, and they call for some comment from those in
authority. If the Pharmacy Acts mean anything at all, it is that
they were passed by the Legislature for the safety of the public,
and that the handling of dangerous drugs should be done by
responsible individuals and not by boys and girls without super¬
vision ; but ridicule of the Acts, and especially by one exercising
judicial functions, does not tend to raise the Bench in the estimation
of the right-thinking public, nor does it tend to guarantee that
amount of safety which the Acts were meant to carry with them. —
Several other members having expressed'their opinions upon the
decisions of Sheriff Mair, it was decided to adjourn the consideration
of the subject for a week.
Plymouth, Devonport, Stonehouse and District
Chemists’ Association, Tuesday, March 23. — At a Committee
meeting the following resolution was passed : —
“ That it recommends the Association furthering Mr. Park’s nomination as a
candidate for the Pharmaceutical Council, and that they should use their
best efforts to make it a success."
This is to be brought forward at the quarterly meeting on
Wednesday, April 17, when the new bye-laws proposed by the
Pharmaceutical Council will also be discussed.
Edinburgh Chemists’, Assistants,’ and Apprentices’
Association, Friday, March 19.— Mr. James MacBain, President,
in the chair. — Mr. George Senter gave a lecture on —
Vegetable Histology,
illustrated by lantern micro- photographic slides. — Mr. W. B.
Cowie then made a statement with regard to—
Percentage Solutions,
in which he stated that the true percentage solution was a
percentage by weight, but there might also be a percentage
solution by volume, containing a given number of grains by weight
in 109 grain measures of solution. The system of a given number of
grains by weight in 100 minims was not a percentage solution.
In the discussion which followed considerable diversity of opinion
was expressed.
Pharmaceutical Chemists’ and Apothecaries’ Assis¬
tants’ Association of Ireland, Thursday, March 18. — Dr.
J. A. Walsh in the chair. — This meeting, which was open to the
members and their friends, was largely attended, the attraction
being an interesting lecture by Dr. Johnston, on —
Bacterial Friends and Foes,
in the course of which the lecturer described what bacteria are,
their position in the vegetable kingdom, their structure, various
forms, habitat, conditions of life, the products of their activity,
methods of reproduction, how cultivated, their weeding-out
processes, and their study.
SOCIAL MEETINGS.
Liverpool Chemists’ Association, Thursday, March 18.
— Mr. A. C. Abraham, President, in the chair. — The annual dinner
of the Liverpool Chemists’ Association was held at the Adelphi
Hotel, and the Chairman was well supported by a full muster of
the members, and by the presence of several of the leading repre¬
sentatives of the medical profession of the city, in addition to
nearly every pharmacist known to local fame. After the toast of
the “Queen” had been duly honoured the President proposed “The
City and Trade of Liverpool,” remarking upon the length of time the
Chemists’ Association had been in existence (some forty -eight years)
and the changes which had come over the town during that period.
The toast was coupled with the name of Mr. W. P. Evans, of the
firm of Messrs. Evans, Sons and Co. , who responded, after which
Mr. Charles Sharp, F.L.S., proposed the “Medical Profession,”
coupled with the name of Professor Carter. In acknowledging
the toast, Professor Carter briefly ran over a few salient points in
the history of the progress of medical science during the last
twenty-five years, and told how the proper organisation of sanitary
reform by means of the Public Health Act had approximated the
standards of health throughout the length and breadth of the land.
— Mr. T. S. Wokes next proposed the toast of the
“Pharmaceutical Society of Great Britain.”
In reply to which Dr. Charles Symes discussed the proposed
alteration of the fee for the Qualifying Examination and mentioned
his reasons for supporting it, at the same time calling attention to the
fact that whatever legislation had done for the betterment of the
trade, it had been brought about by the instrumentality of the
Pharmaceutical Society not for its members alone but for every
individual in the entire body of chemists. In doing this, certain
expenses were inevitable and it was only fair that men on
qualifying should be made to pay such a sum to the Society as
to enable it to prosecute its good work without unduly trespassing
on the funds contributed by its members, who unfortunately
constituted only a small minority of the practising pharmacists.
Of course, the ideal would be that every chemist on qualification
should, by payment of a certain sum, become a life member of the
Society, and doubtless this would ultimately be the goal at which
they would arrive. The succeeding toasts were “ The Liverpool
Chemists’ Association,” proposed by Dr. Cairns and acknowledged
by the President and Mr. T. H. Wardleworth, and “The
Guests and Musical Friends.” The latter — the “ Musical Friends”
— were well deserving of recognition, for the programme rendered
by them was enjoyable in the extreme and of a high degree of
artistic excellence. Messrs. W. J. Chambers, Robertson-Field,
Percy Stone, John Bain, E. A. Keeling, and the accompanist, Mr.
Frank Lobb, divided the honours between them. The proceedings
terminated at about 12 o’clock amid general expressions of satisfac¬
tion at the successful way in which the arrangements had been
carried out by Mr. H. 0. Dutton and the Committee.
Brighton Junior Association of Pharmacy, Wednes¬
day, March 17. — A conversazione was held at the King’s Apart¬
ments, Royal Pavilion, Brighton, commencing at 8 p.m. There
were about one hundred present, including many well-known
Brighton chemists. A short concert was followed by dancing,
which was kept up till a late hour. A thoroughly enjoyable time
was experienced by all. The arrangements left nothing to be
desired, thanks to the efficient management of the President (Mr.
A. T. Jeeves), Hon. Sec. (Mr. C. A. Blarney), and Stewards
(Messrs. W. Howes, A. H. Cupit, and C. G. Yates).
PUBLICATIONS RECEIVED.
A Manual op Chemistry, Theoretical and Practical. By
William A. Tilden, D.Sc., F.R.S. Pp. 600. Price 10s.
London : J. and A. Churchill.
St. Thomas’s Hospital Reports. New Series edited by Dr. T.
D. Acland and Mr. Bernard Pitts. Pp. 510.
St. Thomas’s Hospital Medical School Calendar and Pros¬
pectus, for the year commencing October 1st, 1896. Pp. 118,
London : J. and A. Churchill.
March 27, 1897]
PHARMACEUTICAL JOURNAL.
235
LETTERS TO THE EDITOR.
The Proposed New Bye-Laws.
Sir,- — Allow me a small space to make further reference to the
question of a registration fee, which I still venture to think, not¬
withstanding what you say in this week’s issue, should and could
be charged after examination. Apart from what the 1852 Act
authorises, I submit that even under the 1868 Act, which you quote
in this week’s “Annotations,” such a fee could be charged.
Section VII. of that act reads : “ Upon every such examination
and registration as aforesaid such fees shall be payable as shall
from time to time be fixed and determined by any bye-law,” etc.
Do you not think that the fact of the plural word “fees” being
used clearly indicates that the Council, notwithstanding what has
been done by it and the Privy Council in the past, is empowered
tto make a new bye-law requiring a payment of two fees in future,
one for examination and one for registration ? This you say is im¬
practicable, but although it is unwise to differ from an editor, I
must, in this instance, do so. In regard to my second suggestion,
viz., that only three guineas should be charged on all subsequent
occasions after the first failure to pass, I still think that to again
charge ten guineas, as is proposed, thus doubling the registration
fee on the unfortunate candidate, would be unjust. At most five
guineas would be ample, as it should be purely an “ examination”
fee, as you term it yourself in second paragraph when referring to
Bye-law 23. In the third paragraph you speak of “ a second regis¬
tration fee,” and also of a “ penalty ” for not passing the examination,
but where is there authority in any Act or bye-law for imposing
such on any candidate ?
Edinburgh, March 22, 1897. Claude F. Henry.
Sir, — The proposed alterations in the examination of the
Pharmaceutical Society suggest again the great desirability of
introducing an additional examination which might be called an
“ intermediate ” and be passed at the conclusion of the usual term
of apprenticeship. Every employer who feels an interest in the
progress of his apprentice must have been struck with the dis¬
advantages under which young men work during their apprentice¬
ship in having nothing to look forward to at its termination in the
shape of a test examination. Such an examination on the work
which an apprenticeship should cover to be looked forward to
during the term of apprenticeship and to be passed at its close would
act as a wholesome stimulus alike to pupil and teacher. It would
also be to some extent a guarantee of the possession of at
least a certain amount of knowledge of business details and
elementary scientific work. Beyond this also it would be of
advantage to the student as giving him a certain status while a
junior assistant, which he could not otherwise have — the status of
a partially qualified man. The time that must elapse now
between the entrance on apprenticeship and taking the Minor is
too long, the examination is too far off, and its requirements too
much above him to constitute an aim for the apprentice. He
could work for an intermediate such as I suggest, and it would be
greatly to his advantage to have this definite course before him
during the often somewhat dull and tedious years of his
apprenticeship. I do not know that there is any other profession
that gives no step in its curriculum between its entrance, ‘ ‘ arts ”
exam. , and its qualifying exam. , and I feel sure that such a step
would be a great help and advantage to students. The fees
should be small and the facilities as great as possible. There
need be no interference with the other examinations of the Society.
March 22, 1897. K. K. (86/22).
Sweating the Dispenser.
Sir, — Your leading article of February 13 re the examination
required for Army compounders reminds us that it is two years
since representations were made by the Pharmaceutical Society to
the Local Government Board, protesting against their order
making Army compounders eligible for Poor Law appointments, a
protest which has presumably been without effect. This order,
which in its inception was designed to sweat and to weed out of
the Poor Law the present qualified men, is an instance of what a
so-called “Liberal” Government will do. It first of all enjoins a
short service system for the Army, which gives us an incompetent
soldier, provides him while in the Army with a smattering of a
trade, and finally turns him out a curious compound, half soldier,
half civilian, which it would foist upon a confiding public.
The reproach of fostering sweating should be directed against
the late Government — and the present one too while it allows
the present conditions to continue — and not against the
local bodies, who, at least, are not responsible for the “watering
down ” of the qualification required for the dispenser. We now
know the regulations for the so-called qualification of the Army
compounder, and it is evident that a training of so short a
duration, and an examination so farcical does not properly provide
for the public safety. However, Tommy Atkins’ ailments are not
usually of a very varied nature, and it does not require a long
training to form a so-called emulsion with an alkali and bals.
copaiba, or to put a few grains of zinci sulph. in half a pint of
water, so probably the “qualification” suffices. It is different in the
Poor Law. Stock mixtures comprise only a small proportion of the dis¬
pensing, which from personal observation, I am satisfied is generally
well and carefully done. A dispenser in the service once furnished me
with a list of “ duties ” performed by him during his term of office.
These comprised analyses of drugs, chemicals, urine, water, milk,
paint, portions of the viscera for suspected poisons, etc., etc., a
function, I opine, the Army compounder would find it impossible
to perform. In addition, the dispenser is often called to render
“ first aid” in cases of emergency, to extract teeth (one dispenser
I know is L.D.S.), and to perform minor operations. I do not
know of any slip-shod dispensing in the Poor Law, if it exists it is
the outcome of the lack of recognition by the Local Government
Board of the responsible nature of the duties assigned to the dis¬
penser. Work of undue dimensions is forced upon him by the
Guardians, who, themselves, are ignorant of the consequences of
their action, they merely accept the dictum of the upper Board in
this matter without question. I cannot conceive how anyone can
properly dispense 360 prescriptions in a day of nine hours,
as “Dispenser” in your issue of March 6 claims to have done.
The time permits only 1^ minute for each prescription — this fact
alone is sufficient to condemn it. I ask the whole trade to protest,
by simultaneous representations to the different Members of Par¬
liament, against the continued degradation of the Poor Law
dispenser, and especially to insist upon the exclusion of the Army
compounder from these appointments. I invite the Pharmaceutical
Society to give its aid by providing a room for licentiates to meet
in to discuss matters, ventilate grievances, and to formulate a
programme. I ask the Society to support its licentiates by abolish¬
ing the absurd term of “ Minor” for its qualifying examination,
and not continue to minimise its qualification in the eyes of the
public and authorities by its own nomenclature. The latter step,
a small one, will do more to right Poor Law dispensers and others
than any one act the Society is capable of doing, and is one which
will have immediate results.
March 10, 1897. A.P.S. (84/31).
Peach Kernel Oil and Oil of Almonds.
Sir, — In the Journal of March 13 you report a discussion which
followed a paper read by Mr. R. C. Cowley before the Liverpool
Pharmaceutical Students’ Society, and it appears that, in the
course of remarks by various speakers, one gentleman asked if
there was “ any ready and good means of distinguishing between
almond oil and peach kernel oil.” As the desired information was
not given (according to the report), and the question is one of
practical importance, it may be of interest to call attention to
Maisch’s distinguishing test for the two oils, viz. : On warming
with an equal volume of nitric acid, sp. gr. 1-16, peach kernel oil
gives a yellow to orange-red coloration, genuine almond oil giving
a negative result under the like conditions. From the results of
some personal experiments in that direction, I should think it
would not be difficult to adapt a modification — on colorimetric
lines — to the determination (approximately) of amount of peach
kernel in a mixture of the two oils.
Ashton-under- Lyne, March Ilf, 1897. T. Jackson.
The Proprietary Articles Trade Association.
Sir, — I cannot agree with the opinion of “Catalysis” that the
arguments of Mr. Ingham against the P.A.T.A. “squashed the
case ” any more than I can agree with his own statement. The
fact that he writes under a nom de plume robs his letter of any
value it might have had, as one is led to suspect that it is written
either by one who has not the courage of his convictions, by one
prej u diced against the Association , or possibly by one whose interests
are inimical to the success of the P. A. T. A. In answer to his objections
my experience and that of many of my confreres is that it does serve
the object for which it exists. It does not increase the sale
of quack remedies, and the only way freedom of action is affected
286
PHARMACEUTICAL JOURNAL.
[MARCH 27, 1897.
is one that is beneficial to oneself and the retail trade generally.
The most sanguine well-wishers of the P.A.T.A. recognise the
difficulty of stopping the cutter from procuring supplies, and that
this cannot be effected at once and without trouble and assistance ;
but if it has the loyal co-operation of its members and a majority
of the retail trade there should be no difficulty in doing this. As
the interests of all are affected by cutting, surely it is not too
much to expect that everyone but the cutter will do a little to
help safeguard those interests. “ Catalysis” makes the statement
that the cutter can always obtain a supply from a
friendly brother chemist. The friendly brother chemist
must either be a cutter himself and soon get “ spotted,” or else
must be a very poor business man to supply another who neces¬
sarily injures his own business. The “mushroom” Association
does not advertise to the public, and it rests entirely with the
retail trade if they take up any of the articles advertised in the
Anti-Cutting Gazette. I quite agree with the quotation used by
“Catalysis” from Dr. Macnaughton- Jones’ address as to the
liberty of doing what is right; what the supporters of the P.A.T.A.
are aiming at is against the liberty of doing wrong. What are our
laws framed for, magistrates appointed, and police maintained ?
Certainly not to prevent the former, but to guard against and
punish the latter.
The most charitable conclusion one can come to with regard to
the opinions of “Catalysis” is that he has not yet fully taken in the
situation. He complains that the “ black list ” only affects about
twenty houses, and those all or nearly so stores. This at any rate
is an admission of good work already done. If the great “ stores”
can be restrained, surely success is within measurable distance of
attainment. Many so-called “ cutters ” are so because they have
been driven to it by the competition of these great trading com¬
panies and a small minority within our own ranks. The majority
of the retail trade are no doubt in favour of protection of prices,
and it is a very small minority who damage the interests
of the whole trade by pursuing a selfish policy. If the
large trading companies who reap the benefit of the
advertisement, and who are in a position to buy better than
the ordinary retailer can be stopped selling at unremunerative
prices, there should be no difficulty with the one-man company
store. If “Catalysis” can suggest any better course to pursue than
that taken by the P.A.T.A., I feel sure that the Executive of that
body will accept it, and adopt it, and that he will earn the
gratitude of the retail pharmacist ; if he cannot, surely the attempt
to put this portion of our business on a more satisfactory basis
might command his benevolent neutrality.
March 22, 1897. Charles J. Park.
The Alleged Conversion of Cinchonine into Cinchonidine.
Sir, — In further reference to the above subject I should like to
give two results I have obtained since writing my letter of the
23rd ult. First, when amyl alcohol is used, which contains enough
water to form an aqueous layer with the caustic potash, no cin¬
chonidine, or at most a mere trace, is formed. This may possibly
be the cause of previous failures to obtain it. Secondly, as the
presence of water is objectionable, I tried the experiment of dis¬
solving an equivalent quantity of metallic sodium in dry amyl
alcohol, and thus forming sodium amylate, instead of using potas¬
sium hydrate. By this method I have obtained a yield of cin¬
chonidine equal to 12 per cent, of the cinchonine used, nearly two
and a half times as much as when the hydrate is employed.
Stratford, near London, E. G. E. Shaw.
March 16, 1897.
Business Ways that are Dark.
Sir, — I think the following incident will interest some of your
readers, as I see you have published letters from those who like
myself have been afflicted with a parcel of goods in December
which I had not ordered. I received by parcel post two parcels
of cachous, and a day or two after an intimation that they were sent
on sale or return. On Dec. 19th I replied, “ Having sent these goods
without my instructions I absolutely refuse to take any liability or
responsibility whatever.” I then received 5\d. in stamps with
request to return the goods. I took no notice of it. On March 2
I received post-card asking for return, stating I had asked for
stamps for that purpose (which I had not). I then wrote saving if
I received 2s. 6 d. for storage within three days from that date I
would send them, if not I should charge 2s. 6 d. per month, showing
them there was two sides to this matter. By return I received the
2s. (id. , and returned the goods. Those of our friends who wish to
stop these precocious people putting them to trouble and annoy¬
ance will see how to go on with them, and the publication of this
letter will open the eyes of those who read it.
Sheffield, March 19, 1897. ' G. Ellinor.
“ Lime Juice and Glycerin.”
Sir, — Would it not be as well to remind your readers that in the
Pharmaceutical Journal for May, 1867 (2nd series, vol. viii., page
679) there is a formula for “ Glycerin and Lime Cream ” furnishing
a product and a name to which no exception can be taken. It is
essentially two parts of almond oil with one part of lime water, to
which a little glycerin may be added with perfume, and a trace of
tincture of cantharides. The so-called Persian almond oil may be
used, but not a larger proportion of water. Call it “ Lime Cream”
and all is well.
Marylebone, N~. W., March 22, 1897. J. 0. Hyslop.
ANSWERS TO QUERIES.
Practical Pharmacognosy. — Tschirch and Oesterle’s ‘Atlas der
Pharmakognosie und Nahrungsmittelkunde ’ is published in
London by Williams and Norgate, Henrietta Street, Covent
Garden, W.C., at Is. 6 d. per part. Eleven parts have so far
appeared. [ Reply to H. C. T. G. — 86/12.]
Jalapin.- — It is unreasonable to expect information in books more
than twenty years old to correspond with that in those of more
recent date. The term “jalapin” more properly applied to the
portion of jalap resin insoluble in ether, but some writers apply it.
to the ether-soluble constituent of the resin. German “jalapin”
often consists of the cheaper soluble “ convolv ulin ” extracted from
scammony root. \Reply to S. H. — 84/25.]
Address of German Firm. — The address you require is Dr.
Hermann Rohrbeck, Firma J. F. Luhme and Co. , Karl-Strasse 24,
Berlin, N.W., manufacturer of bacteriological, chemical, and
technical apparatus. [Reply to J. A. — 83,27.]
Dispensing Query. — Yes, spiritus aetheris nitrosi is known to
be “incompatible” with salicylates. The mixture you mention,
Sodii salicyl. , ; Spt. aether, nit. , jji. ; Aq. menth. pip. , §vi. ,
behaves exactly as you describe ; first a pale straw colour develops
in a few minutes, ultimately a deep brown colour and a peculiar
empyreumatic odour is evolved. The crystals you obtained,
which were afterwards redissolved in the mixture, probably
consist of salicylic acid. On standing a couple of days com¬
plete decomposition of the salicylate seems to be effected, and
an almost black liquid results. You should call the attention of
the prescriber to this fact. We have not been able to determine
what the colouring bodies are ; probably the reaction is a very
complicated one. The decomposition may be materially retarded by
removing all free acid from the nitrous ether, by shaking it with a
little recently ignited sodium carbonate. [Reply to J. W. — 84/26.]
OBITUARY.
Coleey.— On March 13, Frederick Coleby, Chemist and Drug¬
gist, late of Poplar. Aged 46.
Hall.— On March 13, John Thomas Hall, late of Seaforth, near
Liverpool. Aged 51.
Alford. — On March 17> Edward Alford, Chemist and JJruggist,
Wadsbridge. Aged 26. Mr. Alford had been an Associate of the
Pharmaceutical Society since 1893.
Dyer. — On March 17, Edward Henry Dyer, Pharmaceutical
Chemist, of Honiton, Devon. Aged 40. Mr. Dyer had been a
Member of the Pharmaceutical Society since 1882.
Bae. — On March 22, Alexander Rae, Chemist and Druggist,
Banff. Aged 87.
COMMUNICATIONS, LETTERS, etc., have been received from
Messrs. Barclay, Barrett, Beckett, Britton, Brown, Buckley, Clarke, Claypole,
Cocks, Colley, Coull, Currie, Dunstan, Ellinor, Ellul, Evans, Everard, Forret,
Francis, Gardner, Goodall, Green, Gregory, Henry, Hill, Hogg, Huck, Hunt,
Hyslop, Jewsbury, Kemp, Kemsey-Bourne, Line, Miller, Mitchell, Morley,
Nall, Park, Peck, Philip, Potter, Reynolds, Robertson, Robins, Southall, Stamp,
Sutherland, Thomson, Warburton, Wardleworth, Wolff.
[Several (Letters and Answers are held over.]
PHARMACEUTICAL JOURNAL.
287
“THE MONTH.”
The gaseous products formed when acetylene
is exploded with less than its own volume of
oxygen have been studied by W. A. Bone and
J. C. Cain, who point out that this gas differs
from methane and ethylene by the readiness
rich it explodes when mixed with comparatively small
volumes of oxygen. Methane will not detonate unless it is fired
with nearly its own volume of oxygen, and ethylene must be mixed
with about sixty-five per cent, of its own volume of oxygen before
it can be fired under ordinary conditions. Acetylene, on the other
hand, explodes when mixed with one-fifth to one-fourth its own
volume of oxygen. When it is exploded with less than its own
volume of oxygen, the products finally obtained are carbon mon¬
oxide and hydrogen, and the excess of acetylene is for the greater
part resolved into its elements by the shock of the explosion wave.
As much as one per cent, of acetylene, however, may be found
amongst the products of explosion, and is possibly due to a re¬
combination of carbon and hydrogen in the rear of the explosion
wave. No other unsaturated hydrocarbon has been detected in
the products of explosion. Methane does not appear to be formed
when acetylene is exploded with less than its own volume of
oxygen, at any rate not in any appreciable amount, but small
amounts of a gas absorbable by solid potassium hydroxide were
invariably found in the products of explosion, this being partly, if
not altogether, due to the presence of carbon dioxide. A final
result of the explosions is that carbon is deposited thickly when
the acetylene is mixed with less than three-quarters of its own
volume of oxygen, but where mixtures contain a larger proportion
of oxygen much less carbon separates. — Journ. Cliem. Sop., lxxi., 26.
W. A. Bone and D. S. Jerdan find that, at a
temperature of 1200°, or thereabouts, carbon
unites directly with hydrogen to form methane,
no acetylene or other un saturated hydrocarbon
being formed at that temperature. Both
methane and acetylene are formed when the electric arc is passed
between carbon terminals in an atmosphere of hydrogen, whilst a
state of equilibrium is finally established between hydrogen,
methane, and acetylene, if the passage of the arc be continued.
Similarly, a state of equilibrium is produced when the electric arc
is passed in an atmosphere of either methane or acetylene under
similar conditions. — Journ. Chem. Soc., lxxi., 41.
Anapparatusforliquefyingairby self-intensive
refrigeration has been devised by W. Hampson,
and it appears to be a great improvement on
that of Dr. Carl Linde, as the weight of the
copper coil required is reduced to less than one-
sixth that in the latter, the time required for liquefaction to less
than one-fourth, and the pressure of the compressed air to less
than one-half. Without the use of auxiliary refrigeration Linde
was able, with a copper apparatus weighing 132 lbs., to liquefy air-
in two hours, with an average higher pressure of 190 atmospheres.
Hampson’s copper tube weighs 20 lbs. only and, when supplied
with air at an average pressure of 87 atmospheres, a jet of liquid
air was seen in twenty-five minutes, whilst the liquid was
collecting in the receiver in thirty-three minutes from the start.
When the apparatus was cooled by continuous working the air
began to collect again in two minutes after emptying the receiver,
and accumulated at a good rate. No auxiliary cooling by carbonic
acid or other agents was used to reduce the temperature of the
compressed air before or after it reached the apparatus. The
Vol. LVIII. (Fourth Series, You. IY.). No. 1397.
Union of
Carbon and
Hydrogen.
Liquefaction
of
Air.
receiver is a glass vessel protected by a vacuum, of the kind
invented by Crookes and improved by Dewar, and the apparatus
can be worked without danger, as in the event of a joint giving
way there is no risk of anything happening beyond “ a mere
blowing off.” — Nature, lv., 485.
A process successfully employed by K. P.
Recovery of McElroy in the recovery of platinum chloride
Waste Platinum waste from potash analyses is based on the
Chloride. use of aluminium turnings. These are added
to a hot aqueous solution of the platinum-
potassium chloride and, in a few minutes, a platinum-aluminium
couple is formed and reduction goes on vigorously. Hydrochloric
acid may be added to promote the settling of the platinum
liberated and, after reduction is complete, more acid is added to
dissolve excess of aluminium, The clear supernatant liquid
having been passed through filter paper to separate any suspended
platinum, the spongy platinum is then washed until free from
chloride. It is next covered with nitric acid and heated for the
purpose of removing any copper that may have been contained
in the aluminium. After further washing the platinum black
produced is dissolved in aqua regia to form chloride. — Journ.
Amer. Chem. Soc., xix.,258.
Schafer dissolves 50 grammes of aloes in 300
Determination C.c. of hot water, slightly acidulated with a
Of few drops of hydrochloric acid. The solution,
Aloin. after standing for the resins to separate, is
poured off and mixed with 50 C.c. of 20 per¬
cent. ammonia solution. This is followed by a solution of 15
grammes of calcium chloride in 30 C.c. of water. On stirring
rapidly the aloin-calcium compound separates out, and after stand¬
ing fifteen minutes is collected and drained, or separated in a centri*
fugal machine. The drained mass is mixed in a mortar with a
slight excess of hydrochloric acid, the resulting mixture of calcium
chloride and aloin dissolved in the smallest possible quantity of
boiling water, filtered, the filter washed with a little boiling water,
and the filtrate crystallised at a low temperature by means of ice.
In this manner from 15 to 30 per cent, of well-crystallised, light
yellow aloin was obtained from various kinds of commercial aloes.
— Pharm. Zeit./ir. Russ., xxxvi., 65.
Commenting on the confusion that has arisen
Iodothyroidin. in the nomenclature of thyroid preparations,
through the use of trade names which are mis-
©
leading and often incorrect, Catillon, in a communication to the
Societe de Therapeutique, describes a method of preparing the active
portion of thyroid for medicinal use in the form of a standardised
product, which he calls iodothyroidin. It is prepared as follows : —
The glands are submitted to pancreatic digestion with pancreatin
and water ; the residue is extracted with petroleum ether, dissolved
in dilute soda solution and filtered, the filtrate slightly acidulated
with dilute sulphuric acid, when the active principle is precipitated.
This is collected and washed, the amount of iodine in a portion
determined, and sufficient sugar of milk added to the bulk to reduce
the iodine content to 0"0003 gramme in each gramme of finished
product.— Les Nouv. Rem., xiii., 129.
This new preparation of ergot is obtained by
Ergotinol. exhausting powdered and oil-free ergot with
water. The extracts obtained are treated with
acids and hydrolised. The acid is then neutralised and alcoholic
fermentation induced. The product is then subjected to dialysis,
and concentrated until 1 C.c. of ergotinol corresponds to 0"5 grm.
of extractum secalis cornutum. Ergotinol is said to be a substi¬
tute for the extract, without possessing the unpleasant pro¬
perties of the latter. — Pharm. Zeity., xlii., 141.
288
PHARMACEUTICAL JOURNAL.
[April 3, 1897
Dr. E. Buchner has extracted from yeast by
Ferment pressure a liquid containing an alcohol-pro-
from ducing ferment which is capable of causing
Yeast. cane-sugar or grape-sugar to ferment in the
absence of yeast-cells. Milk-sugar is not
affected by the ferment. The addition of chloroform to the liquid,
•even up to the saturation point, does not inhibit the fermentative
process, although it causes a rapid precipitation of albuminous
matter. The liquid expressed from the yeast coagulates when
heated to about 50° C., and the power of exciting fermentation is
then entirely lost. It was also found that in the active liquid the
ferment diffuses very slowly, if at all, through parchment paper.
The ferment has been named “zymase” by its discoverer, and
apparently it is of a proteid nature, but further investigation
will be required to decide this and other doubtful points. —
Berichte and Nature, lv. , 442.
According to Sassarini ( Analli di Chim. et
Composition Farmacol.) gamboge contains: — 1st, a gum
Of analogous to arabin ; 2nd, an essential oil
Gamboge. boiling from 160° to 210°, containing a terpene
and a camphor (this oil does not appear to have
been previously recorded) ; 3rd, isovitinic and acetic acids ; 4th,
a phenolic ester ; 5th, a resin ; 6th, methyl-alcohol and other
•higher homologues ; 7th, a liquid with a fruity odour, boiling at a
high temperature, and presenting the characters of an aldehyde or
an acetone. He is of opinion that the phloroglucin reported as
present by other workers has been a decomposition product. —
Journal de Pharm. [6], v., 171.
This is the name which Boehm gives to a
Aspidin. substance obtained from the ethereal extract
of male fern in the proportion of 3 per cent.
It has the formula Cs3H2707, and forms colourless crystals which
melt at 124 ’5° C. ; these are insoluble in water, soluble in
alcohol, benzol, ether, and alkalies. Aspidin is poisonous, but
nothing certain is known about its therapeutic effect. Besides
aspidin, Boehm has further isolated albaspidin, aspidinin, aspi-
■dinol, and a few acids from the extract. — Pliarm. Zeitg., xlii., 79.
Professor Remington publishes the results of
Aeetie Acid some experiments, the object of which was to
as a determine whether acetic acid cannot be made to
Menstruum, replace alcohol in at least some of the medicinal
preparations now in common use. On account of
the antiseptic power of acetic acid, he considers that there can be no
question that vinegars, if properly made, could advantageously
replace many tinctures. He points out, also, that slightly acidulated
liquids are palatable to most patients and that vinegars, when com"
bined in mixtures with syrups, would be particularly acceptable
inasmuch as the acid would counteract the cloying sweetness of the
syi’ups. Another recommendation advanced is the desirability of
having alternative preparations of the same drug so that physicans
may avoid giving alcoholic preparations to patients who may beliable
to become victims of the liquor habit. The objection to the presence
of strong acetic acid in a preparation is met by the suggestion
that the acid might be got rid of by evaporating at a very low
temperature and then re-dissolving the extract in some other
solvent, the process adopted in the preparation of ipecacuanha wine,
B. P. The results of the forty-one experiments recorded merely show
that acetic acid can advantageously replace alcohol in the extraction
of nux vomica, the “acetract” prepared with 10 per cent, acetic acid
and proved to contain 15 per cent, of mixed alkaloids, having been
dissolved in alcohol of varying strengths to form tinctures. From
these results it would appear that acetic acid may prove useful in the
case of drugs difficult to exhaust, and that the solid prepara
tions thus obtained may be readily assayed and standardised.
They can then be re-dissolved in mixtures of alcohol and water of
different strengths, with or without the addition of glycerin, and
if the proper menstruum be chosen the residue will be inert and
may be filtered out. Sanguinaria, kola, ipecacuanha, squill, cin¬
chona, and colchicum seed are referred to as having also been
experimentally exhausted with acetic acid, but the results are not
given.— Amer. Journ. Pharm., lxix., 121.
In a paper embodying the results of a large
Therapeutic number of determinations of the ash yielded by
Activity of various drugs, C. H. La Wall remarks that,
Drugs. inasmuchas the therapeutic activity of any given
drug is attributable to the constituents peculiar
to that drug, irrespective of the physiological effects produced by
so-called inert cellular tissue, it might, therefore, truthfully be
said that the therapeutic effect of any given drug is the algebraic
sum of the effects of its proximate constituents. The word effect
is used in a relative sense only, as no uniform or fixed value can be
given in view of the fact that in no two cases of administration are
the conditions exactly similar. The inorganic constituents of drugs,
it is pointed out, may play a very small part in the physiological
action of a drug, but in the present state of our knowledge no
factor, however slight, should be ignored. — Amer. Journ. Pharm. ,
lxix., 137.
L. E. Sayre has compared the structure of
Comparison Rhamnus purshiana, R. frangula, and R. cali-
Of Rhamnus fornica, and thinks that, though the resem-
Barks. blance between them renders distinction diffi¬
cult, a few points of dissimilarity revealed by
the aid of the microscope and appropriate reagents may prove of
some value in distinguishing the powders. Stone cells, he states, are
absent from R. frangula, while the other two barks contain a large
number of them, scattered in large irregular groups below the
cork and usually outside the bast region. In the case of
R. purshiana and R. calif ornica the microscope failed to reveal any
satisfactory means of differentiation, but maceration in dilute
alcohol for several days causes the powder of the first-named
to assume an orange-yellow colour and the various tissues to come
out more clearly when examined ; the powder of R. californica,
however, becomes purplish, and the tissues seem to be obscured
by a dark colouring matter. Potash solution causes the powder
of R. purshiana to become deep red, and that of R. californica
assumes an orange colour. Slight hope is held out that these tests
will avail in dealing with mixed powders, and it may be doubted,
therefore, whether they possess much practical value. — Amer.
Journ. Pharm., lxix., 126.
A. Schneider has made a comparative study
Histology of true or Banda mace ( Myristica fragrans) and
Of wild or Bombay mace (M. malabarica). He
Maee. finds that their anatomical characters are essen¬
tially different, the most marked differences
occurring in the epidermal tissues and in the amylo-dextrin grains.
The epidermal cells of true mace are described as being much
elongated in the direction of the long axis of the arillus and tan¬
gentially flattened ; those of Bombay mace, on the other hand, are
radially flattened. The amylo-dextrin grains of true mace vary
greatly in size and form, some (5 g. x 14u) being nearly
rectangular and much elongated, whilst others (6^x9/!) are ir¬
regularly oval, and some are very small (2fx to 6/x in diameter).
Others, again, are much thickened at one end (flask-shaped), and
in most of the grains crystalloid bodies may be detected. The
amylo-dextrin grains of Bombay mace are usually more or less
spheroidal, some being quite irregular, and very frequently they
April 3, 1897]
PHARMACEUTICAL JOURNAL.
289
occur in groups. They vary from 2/j. to 10/* in diameter, and their
crystalloid contents seem much smaller than those in true mace.
In addition the contents of the oil-cells of the two kinds of mace
differ chemically, those of the Bombay variety being distinguished
by a colouring substance which does not occur in appreciable
quantities in true mace, if at all. On the addition of potash
solution the cell contents are dissolved and an orange-red
colour gradually develops in the presence of this substance, the
reaction requiring from one to three minutes to reach its
maximum intensity. If sulphuric acid (25 to 50 per cent.)
be noW added the colour changes to yellow, and there is a partial
precipitation of the colouring substance. This reaction is said to
be a certain proof of the presence of Bombay mace, as true mace
when treated with alkalies gives only a “ light” orange-red colora¬
tion which is changed by acids to a “faint” yellow. It is claimed
that the presence of an almost infinitesimal quantity of wild mace
can thus be detected, and that by the aid of the microscope, mixtures
of the two kinds in the state of powder can be recognised as such.
— Journal oj Pharmacology, iv., 57.
Sayre states that this root is considered
Balsamorrhiza invaluable in cases of heart trouble, also as a
Terebinthaeea. cure for the habit of tobacco smoking. The
plant is a native of western Idaho and eastern
Oregon, growing in hard stony soil. It is a Composite. The root,
when peeled and baked, serves as an article of food for the
aborigines, and the achenes are also eaten. The colour of the root
is light brown, shaded to almost black. It is deeply fissured
from the uniting of branches, and frequently annulate. The
wood fibres are light yellow, and the root is of an open spongy
texture, the pores being filled with a brownish-yellow resinous
balsam. The root has a strong terebinthinate odour, and
is very inflammable. It is exceedingly pungent and aromatic
in flavour, producing a persistent tingling sensation upon the
tongue and throat. The virtues of the root are due apparently to
an oleo-resin, which is highly aromatic. This resin is soluble in
alcohol, and has a strong odour, which may be said to resemble a
mixture of a camphoraceous or terebinthinate oil and an oil from
one of the umbelliferous plants. It would appear that this plant
has the properties of a stimulant and carminative. Whether
it acts upon the heart it is impossible to say until physiological
experiments can be made. — Drug. Circular, xli., 32.
Gerpen made the remarkable observation
Poisonous that after having deposited the honey in their
Honey. cells, certain American bees collect the pollen
of the male Indian corn, and work it well into
the honey. If the honey is used before this operation has taken
place, it ferments quickly and produces griping and violent
diarrhoea. It would seem, therefore, that the pollen of Indian corn
possesses an antiseptic action which protects the hcney from
fermentation. — Amer. Pharm. Monatsb., ii. , 45.
According to Dr. A. Tschirch, resin, oil, and
Formation other secretions are never formed within the
Of Secretions cell-membrane, but in a special layer known as
in Plants. the resinogenous layer. The septa which occur
in the vittae of Umbelliferae are the remains of
this layer. To the substance of which this layer is composed the
author applies the term “ vittin.” It is of a pectinaceous character,
and appears to be identical with the substance of mucilage. In
schizolysigenous passages, like those of the Rutacere, there is first
a cap-like formation of the resinogenous layer, followed by a disso¬
lution of the cells and a resorption of the protoplasm. — Sitzber.
68 Versammlung deutscher Naturforscher u. Aerzte, 1896.
From the result of a series of experiments
Assimilation made by MM. E. Laurent, E. Marchal, and E.
Of Carpiaux, on the assimilation of the nitrogen con-
NitFOgen. tained in ammonia and that in nitric acid by the
higher plants, it appears that assimilation of
nitrates does not take place in the dark ; the action of the ultra¬
violet rays is necessary for the process. For the assimilation of
ammoniacal salts, the action of the same rays is of predominant
importance, but the luminous rays may incite a feeble assimilation
of ammonia in etiolated leaves. The action of chlorophyll is
declared to be not essential ; etiolated leaves assimilate ammoniacal
nitrogen even better than green leaves. The assimilation of nitric
nitrogen gives rise to a temporary production of ammonia. — Bull.
Acad. Roy. Sci. Belgique, \ ol. xxxii., p. 815.
In an interesting paper in the Transactions of
Pigments the Botanical Society of Edinburgh (v ol. xx. ,p. 534)
Of Miss M. J. Newbigin gives a detailed account
Plants. of the various colouring matters of leaves and
flowers, which she divides into lipochromes and
anthocyans, the former being insoluble, the latter soluble in water.
The authoress states that there is no evidence that lipochromes are
in any way derivatives of chlorophyll. She groups them into two
classes, eucarotins and carotinins. Anthocyans are probably
derivatives of tannins. The theory that their chief purpose is to
protect chlorophyll against decomposition in a strong light is
scarcely in harmony with some of the conditions under which they
are commonly formed, as, for example, in young shoots in spring,
and in autumn leaves. Etiolin is probably nearly allied to chloro¬
phyll, these two being nearly the only pigments in the vegetable
kingdom which contain nitrogen.
Herr G. G jokie states ( Sitzber . A had,. Wiss.
Fruit and Seed Wien, 1896) that the threads of viscin, which
Of are formed when mistletoe berries are opened,
Viscum. are derived from the membranes of cells which
have been artificially drawn out. They give all
the staining reactions of cellulose. The mucilage which surrounds
the hypocotyl of the seedling is not identical with viscin ; it is
stained yellow by chlor-zinc-iodide, and a beautiful red by sesqui-
chloride of ruthenium. The lignified elements of the endocarp of
Viscum album are reticulated cells and spiral vessels. The
exceptionally strong protection of the seeds of the mistletoe
against evaporation, which enables them to germinate even in the
exsiccator, depends on the development of a thick-walled cuti-
cularised epiderm to the endosperm covered by a thick coat of wax.
Professor H. Molisch states that algae thrive
Food-Materials best in a slightly alkaline nutrient solution.
Of while acid kills them or arrests their growth.
Algae. These facts have a strong bearing on the
growth of fresh- water algae in streams and in
lakes. Waters in which algae are found most abundantly in
Nature are slightly alkaline. In the case of those algae which
especially require calcium, this element cannot be replaced by
sodium, lithium, rubidium, or caesium. Potassium arseniate is
highly poisonous to algae, while potassium arsenite is harmless in
small quantities. — Sitzber. A lead. Wiss. Wien, 1896.
In dilute solutions of citric acid, Herr C.
Acid-loving Wehmer finds a fungus-mycele belonging tc
Fungi. Verticillium glaucum. In solutions containing
tartaric acid, Citromyces makes its appearance.
Penicillium luteum was found when nutrient solutions containing
sugar were treated with citric acid. When tartaric acid was used,
Aspergillus niger took its place. — Beitrdge zur Kenntniss tinheimischer
Pilze, vol, v.
290
PHARMACEUTICAL JOURNAL.
[April 3, 1897
Prof. W. Pfeffer has performed a series of
Formation experiments for the purpose of determining
Of Dias- the conditions under which diastase is formed
tase in Fungi, in some of the lower plants — Penicillium
glaucum, Aspergillus niger, Bacterium mega-
terium. He finds that an increase in the amount of sugar in the
nutrient fluid always has the effect of decreasing the production
of diastase ; but the same result was not produced when the sugar
was replaced by some other carbohydrate, or by glycerin or
tartaric acid. The arrest in the production of diastase is not, he
considers, a purely chemical or physical phenomenon, but is rather
one of irritation exerted on the organism by a solution of sugar of
a certain degree of condensation. — Ber. Suchs. Gesett. Wiss. Leipzig,
Dec. 7, 1896.
MM. G. Riviere and G. Bailbache have
Influence Of attempted to determine the question of tho
the Stock influence exercised by the stock on the graft, by
On the Graft, grafting the same variety of pear on two
different stocks, the wild pear and the quince.
They find, as a general result, that the mean weight of the fruit
produced is considerably greater in the plant grafted on the
quince than on that grafted on the wild pear, that the density of
the fruit is also greater, and that the amount of free acid and of
sugar contained in it are also larger. — Comptes rendus, Acad. Sci.,
Paris, 1897, p. 477.
In the Transactions of the Botanical Society of
Germination Edinburgh (vol. XX., p. 492), Mr. T. C. Day
of publishes the result of a series of observations,
Barley. illustrated by a number of elaborate tables,
on the germination of barley with restricted
moisture. He finds that an increase of moisture during germina¬
tion always induces a corresponding increase in the amount of
carbon dioxide produced. Taking the production of carbon
dioxide as the measure of the rate of growth during germination,
the period of greatest activity, with varying quantities of moisture,
is generally about the third or fourth day.
Mr. R. S. McDougall has collected a number
Poisonous PPO- of facts with regard to the poisonous pro¬
perties Of perties of the seeds of Lathyrus sativus and
LathyPUS sativus. of some other leguminous plants. He states
that the continual use of pulse by man as a
daily article of food leads eventually to paralysis of the lower
limbs, various instances of this being recorded in Scotland and in
India. During the seventeenth and eighteenth centuries pulse
was forbidden as an article of food in Germany and in France. On
horses it has also an injurious effect, causing roaring, the only
effectual cure being tracheotomy. On swine it produces paralysis
and spasm. The alleged instances of the poisonous effects of Cicer
arietinum, the chick-pea, are probably due to Lathyrus sativus
having been mistaken for it. The poisonous alkaloid of the seeds
of Lathyrus sativus does not appear at present to have been separated.
• — Transactions, Bot. Soc., Edinburgh, vol. xx., p. 301.
Keating Stock makes an improved zinc-copper
Improved couple for reducing nitrates in the course of
Zlne-Copper water analysis, thus : After filling a 7-oz. wide-
Couple. mouthed stoppered bottle nearly to the neck
with granulated zinc, add water, then a few
drops of sulphuric acid (1 to 3), and 10 C.c. of 3 per cent,
copper sulphate solution. The stopper is inserted and the
bottle vigorously shaken for one minute, the stopper being held
by the finger, and the operation performed over the sink. The
stopper is now removed and the mouth of the bottle covered with
a piece of soft copper gauze. The couple is then thoroughly
washed at the tap and drained ; 100 C.c. of the water to be
analysed is placed in the bottle, the stopper securely inserted and the
bottle allowed to stand at a temperature of from 20 to 25° C. for
forty-eight hours. The test is completed by thoroughly shaking the
bottle, drawing off 50 C.c. of the water, adding this to 200 C.c. of
ammonia free water in a flask or retort, running in 5 C.c. saturated
sodium carbonate solution, distilling and Kessler ising as usual.
The couples will last for many months after being washed and
re-coppered. — Journ. Soc. Chem. Ind., xvi. , 107.
Francois lately published a note on Viburnum
Viburnum prunifolium in which it stated that caproic
Prunifolium acid was present, although the formula given
was that of oenanthylic acid. Schamelhout has
now reviewed the work, having prepared the ethyl and methyl esters
of the acid and its metallic salts, which prove it to be those of
valerianic and not caproic acid. — Annales de Pharm. [3], iii. , 114.
C. L. Norton and R. R. Lawrence state that,
Condensers by the use of a condenser of considerable
and capacity, an induction coil may be driven more
X-Ray Tubes, satisfactorily, and gives a much more powerful
means of exciting X-ray tubes. The primary-
must be replaced by a special one consisting of a few tarns of
heavy wire on a finely laminated core, special attention being paid
to the insulation. In the case of a vertical coil it is recommended
that the laminated coil be placed in a glass tube, the primary
wound upon the latter, and the whole placed in a large heavy tube
closed at the bottom and filled with oil. Tubes and screens
are much more brilliantly illuminated with this arrangement than
normally, and better effects are obtained, both photographically
and otherwise. — Nature, lv., 461.
G. L. Heath describes a calibrated weighing
A New flask, which possesses some advantages over
Weighing the ordinary graduated flasks in use. The
Flask. neck of the flask is surrounded by an annular
cup, the outside of which is ground to fit a
light glass cap that slips over it. A little soft paraffin may be used
on the ground portions of the ring and cap, as the solution con¬
tained in the flask never comes in contact with the latter. Solutions
may thus be kept for some time without any change in weight, and
the flask is especially adapted for weighing liquids, such as standard
ferric chloride solutions for titrations. After weighing and pouring
off any portion of the contents the little annular cup retains
any drops that may run down outside the neck of the flask. —
Journ. Amer. Chem. Soc., xix., 198.
The use of aluminium in condensers is
Aluminium referred to by T. H. Norton, who describes
Condensers, one in which the outer jacket was of glass and
the inner tube — measuring 122 Cm. in length,
1 Cm. in external diameter, 8-5 Mm. internal diameter, and
weighing 29 Gm. per metre — of aluminium. The tube was bent
at right angles 15 Cm. from the end, thus permitting of connec¬
tion with a distilling flask without allowing the condensing
vapours to come in contact with any substance but the metal.
Ethyl alcohol, benzene, nitrobenzene, chloroform, ethyl ether,
and acetone were shown to be capable of very rapid distillation
with the exceedingly short tube of this condenser, on account of
the high conductive power of the aluminium, and the residues
left showed that there was practically no attack upon the metal.
In connection with the distillation of water it was found that
aluminium possesses about the same advantages over glass as tin,
whilst in lightness and conductivity it is much superior to the
latter. — Journ. Amer. Chem. Soc., xix., 153.
April 3, 1897]
PHARMACEUTICAL JOURNAL.
291
THE LATIN OF PHARMACY.*
BY GEORGE COULL, B.SC.
( Concluded from 'page 273. )
My contention all through is that we should put accuracy or
correctness in the fore front and consistency last. The oils of the
Pharmacopoeia furnish examples of the immolation both of correct¬
ness and consistency. Oleum amygdalae is translated in the B.P.
as almond oil, which is not a correct rendering, it ought to be oil
of almond. Dr. Attfield objects to the United States Pharmacopoeia
rendering magnesii sulphas as magnesium sulphate, but there is no
difference — not in the slightest degree — between that and oleum
amygdalae as almond oil in the B.P. But we have here surren¬
dered a good classical term used by Pliny, namely, oleum amygda-
linum, oil made from or pertaining to almond, i.e., almond oil.
Then oleum caryophylli and oleum cubebae are rendered oil of
cloves and oil of cubebs respectively. Why should the English of
these be in the plural any more than oil of caraway or oil of
coriander ? This is surely inconsistent. Oleum myristicae ex-
pressum has as a synonym adeps myristicae from the 1864 B.P.,
which is a very inconsistent term, and ought to be omitted,
adeps being the soft fat of an animal, besides which it is never
used now. Butyrum myristicae would have been a more consistent
as well as accurate name to call it from its physical appearance, in a
manner similar to that in which oleum theobromatis is called
cacao butter. Gray’s 1 Supplement,’ 1831, says nutmeg butter
floats on the surface of the water in the still when nutmegs are
distilled for their oil.
The word adeps reminds me that I have had for some time a
predilection for a reversion to the old name adeps suillus for the
sake both of consistency and accuracy. We have adeps lame
introduced into the Pharmacopoeia, although I think adeps lanarius
would be the more classical way of putting it, and by the renas¬
cence of old remedies we may have adeps anserinus, ursinus or
vulpinus in use at any time. In fact, there actually was a strong
claim put forward not long ago for a trial of “ oleum anseris ” or
goose-grease by Dr. Langford Symes in the Dublin Journal of
Medical Science, f The genius of the Latin language prefers an
adjective when possible, instead of a noun in the genitive to
describe things. This has found expression in oleum camphoratum,
phosphoratum, betulinum, cadinum, etc., and if carbolic acid is
added to the B.P. it is hoped it will be under the name of oleum
carbolatum. It is only when there are two oils from the same
source, a volatile and a fixed oil, that we run any risk of con¬
fusing them. This is more especially the case when the name
applied to the one was once used for the other. In the P.L. ,
1851, oleum myristicae was defined as the concrete oil
expressed from the seed of Myristica officinalis, while in the B.P.,
1867 and 1885, it was defined as the volatile oil of nutmeg. I beg
to suggest destoleum as the best word that could be applied to
the volatile oils if such a term be ever required, being
accurate, consistent, and definite. The only official volatile
oil that may be obtained otherwise than by distillation is
oleum limonis, but the name destoleum would imply that it could
be distilled. Altheroleum, which has been suggested, is, I think, too
cumbrous, besides implying a connection with ether which they
have not, except in so far as they are liquids and volatile. The only
other oil I have to mention is oleum pini sylvestris. I have two
questions to put concerning it : Why is it translated fir-wool oil,
which, according to Squire, is a registered trade mark ? And why
is it spelt with a “y”? The correct rendering would be oil of
Scotch fir, or the more definite name would be oleum pini sylvestris
foliorum — oil of Scotch fir leaves. Regarding the spelling, Smith’s
Dictionary gives “ silva (less correctly sylva),” and so on for all its
derivatives ; Fliickiger and Hanbury give silvestris as the spelling,
but Linnaeus, in his ‘Species Plantarum’ (2nd ed., 1763), has it
sylvestris. It is, therefore, a question whether it ought to be
changed to silvestris. If the latter is the purer Latin I think it
should be so altered.
There are many cases in the Pharmacopoeia where consistency
might be had and it is not. There are two preparations which are
made by perfectly similar processes, yet one is called an oleo-resin,
and the other a liquid extract, these are oleo-resina cubebae and
extractum filicis liquidum, the U.S.P. includes both as oleo-resins,
the name of the latter being oleo-resina aspidii. Gum acacia is
included as acacise gummi, and the only other gum in the B.P. is
called simply tragacantha. Benzoin, chrysarobin, elaterin,
* Read before the Glasgow Pharmaceutical Association
f Pharmaceutical Journal, lv., 98.
ergotin, lupulin, paraffin, salicin and santonin are latinised, while
aloin, pepsin and pyroxylin are left severely alone. The name
sometimes given to lupulin — glandular lupuli — ought, I think, to be
adopted as the official designation to distinguish it from lupuline,
the volatile alkaloid. Balsamum peruvianum and balsamum
tolutanum are given in English as balsam of Peru and balsam of
tolu, a literal translation which is preferable would be Peruvian
balsam and tolu balsam. Numerous Latin names are given in the
singular with the English equivalent in the plural — galla, galls —
cubeba, cubebs — cantharis, cantharides. The U.S.P. has nutgall
(probably to distinguish it from ox-gall) and cubeb, but adheres to
cantharides, in this there is an attempt at consistency. Then again
some of the seeds are mentioned in the plural— cardamomi semina,
staphisagrise semina, some simply by name without specifying
semina — strophanthus, myristica, nux vomica, while physostig-
matis semen is in the singular. Why are filix mas, gelsemium
and zingiber deprived of part of their appellation, namely
rhizoma — are they any better known than podophyllum,
serpentaria or valeriana ? We have wheaten flour under the
name of farina tritici, and linseed meal as lini farini, why this
inconsistency ?
Dr. Attfield in his famous “ The Pharmacopoeia and its Critics ”
gave as the reason for putting limonis succus and mori succus
where they are, that they are fruit juices, while the others are
medicinal juices, and that it was a perfectly simple and intelligible
arrangement. My opinion is that it would be much more
intelligible and certainly much simpler to place them with the rest
of the succi. Digitalis is translated foxglove, hyoscyamus,
henbane, and conium, hemlock; while belladonna, aconitum and
stramonium are not given their ordinary English equivalents.
Most of the leaves are called folia, as buchu folia, maticae folia, and
uvae ursi folia, but coca stands naked and not ashamed.
On careful consideration it will be seen that the only way to
obviate inconsistencies of the above description is either to adopt
the U.S.P. plan of naming the materia medica as shortly as
possible, never distinguishing the part that is official except in
cases where there is a chance of making a mistake, as aconiti folia,
aconiti radix, conii folia, conii fructus, or to revert to the sonorous
and highly descriptive names of the P.E., 1817, which by no means
erred on the side of brevity. Some of these names were
very diffuse, they were definite enough, but sadly lacking
in conciseness. Myristicae moschatse involucrum nuclei,
vulgo, macis, oleae europaeese oleum fixum, melaleucae
leucadendri, oleum volatile, ferulas assaefcetidae gummi-resina,
eugeniae caryophyllatae flores, and rorismarini officinalis cacumina
are a fair sample of their style. Of the two methods the former
will without doubt commend itself to most, but I should not like
to say it is the better.
Ince, in a paper read at the Oxford meeting of the British Phar¬
maceutical Conference, 1894,* deals with the subject of indeclinable
nouns. I am in accord with most of his ideas, and take this oppor¬
tunity to mention one or two opinions of my own. The only point
in which I differ from Mr. Ince is with regard to the declension of
kino and cusso. I would keep kino indeclinable and call cusso by
its botanical name, hagenia. Cusso being actually part of the
plant could with perfect consistency be designated by the name of
the plant, while kino as an educt of the tree is more appropriately
named as at present, having pondo (a pound) an indeclinable noun
for company. Regarding several other official names, such as
buchu, jaborandi, cascara sagrada, they ought to be changed into
Latin, the old names being retained as synonyms, their prepara¬
tions would read thus — infusum barosmse, tinctura pilocarpi, and
extractum rhamni purshiani. It is very desirable that in
future when any new article with a name native to the
country that produces it is introduced into pharmacy, a
latinised name should immediately be given it, and the native
name discarded — at any rate this ought to be done whenever it
becomes official. It is very difficult once a name has got a footing
to discharge it, but it should be done when the name is in its
infancy. The U.S.P. is to be commended for giving partial effect
to these principles in the case of extractum pilocarpi fluidum and
extractum rhamni purshianae, though still adhering to extractum
buchu fluidum.
In discussing Ince’s paper, Martindale thought it best to make
such words as thymol, sulphonal, chloral, etc., indeclinable. The
Continental fashion with words ending in ol is to make them of
the second declension. The Swiss, Italian, and German Pharma¬
copoeias contain examples of this in the shape of salolum, ft-naph-
* Pharmaceutical Journal [8], xxv., 199,
292
PHARMACEUTICAL journal.
[April 3, 1897
tholuin, mentholum, and thymolum. If the authorities decide to
make official names of this kind declinable, which seems desirable
on the chance of the British Pharmacopoeia being once more pub¬
lished in Latin, it might be as well to adopt Ince’s suggestion to
make them of the third declension, having the example of alcohol
-Qlis before us.
When a new substance is included in the B.P. it is absolutely
necessary that its latinity be correct. Erigeron canadense (for
example) is in the U.S.P., but Smith gives the gender of erigeron
as masculine. Which is the correct one ? Sal carlsbadense
factitium is in several foreign pharmacopoeias, but sal is an
exception to nouns in al being neuter. It is mostly masculine,
rarely neuter, and is always masculine in the plural. Why should
the exceptional gender be taken as the correct one to use ?
Drug-list Latin is sometimes very humorous reading, the vagaries
in the latinity and spelling being somewhat startling, those of the
latter especially being quite according to the taste and fancy of the
speller. But that is too wide a subject to enter on now. I have
only a few words to say on the quantity of Latin words, and then
I am done. How often we hear camphora, atropa, pilula, radlcis,
cascara sagrada, saccharum, and how it grates on the ears of
some of us. There is great need for a prosodial table of official
substances — which need the B.P.C. Executive has noted in its
blue-list. Had I a little more time, the compilation of such a table
is a thing I should take great pleasure in doing ; but to verify the
quantity of every word would take a very considerable time. The
U.S.P. (always abreast of the times) gives the accented syllable in
the index to the Pharmacopoeia.
The Americans have evidently followed Pereira’s ‘ Materia Medica,’
but some of their accents are not according to the quantity of the
original, e.g., ammonf&oum is given ammoni'acum, and carbonas as
carbonas. Where Pereira gives graveolens Smith says gr&veSlens.
Until we have an official prosody the best thing for those who wish
to pronounce their words as the Romans would have done is to
study Ince’s ‘ Latin Grammar of Pharmacy. ’ I would impress upon
all our younger friends that if they have any desire for accuracy in
this matter they ought to begin young, and not be content with
pulv. mag. sulph., inf. gent, co., tinct. camph. co. , etc., but try
to be able to give the complete terminations and correct pronun¬
ciation of every word they use. By doing this when young there will
be so much the less of the ‘ Selecta e Prescripts ’ to be crammed
into them afterwards, very often in a limited period of time.
THE ART OF LITERARY COMPOSITION *
BY JOSEPH INCE.
Kindly distinguish between “an art,” or “the art of doing
something,” and Art. Art is genius rendered manifest, as in
sculpture, painting, poetry or music ; an art concerns mechanical
manipulation with a view to attaining excellence. Art in the
highest sense is always indebted to attention paid to certain rules,
and as exemplified in literature is never seen to greater advantage
than when aided by the art of composition.
I wish to say a few words on this subject, carefully avoiding the
semblance of a dictatorial spirit, or any suggestion of omniscience ;
nor do I wish these remarks to be too high-flown, but simply such
as may be of use. We do not aspire to be great writers, but we
do desire to improve our powers of literary observation ; to enter
into the joy of being able to admire, and by studying good
examples to write sentences pharmaceutical or on subjects of
general interest which others may like to read. The art of com¬
position includes those aids, on the diligent cultivation of which
many branches of literature depend for their success ; it concerns
the noblest and the simplest forms of writing or of speech ; it is
present where least suspected. The art depends on the power of
taking infinite pains, by which Carlyle defined genius, but by an
ever-recurring misquotation, his essential concluding words are
omitted. The original sentence ran thus: — “Genius, which means
transcendenb capacity of taking trouble, first of all ” [see ‘Frederick
the Great,’ vol. i., p. 407, 3rd edition]. The art relates to the
choice of words ; their right and musical balance ; the charm of
simplicity as well as to clearness and consequent strength of
expression ; and lastly to sequence of ideas.
All this united goes to what constitutes Style ; no man however
gifted can afford to neglect these aids ; such neglect brings with
it its own punishment, and he who trusts to facility alone is more
unjust to his own powers than to the public for whom he writes.
Poetry itself, though ever and anon it rises into sublime passages
* Read before the School of Pharmacy Students’ Association, March 26, 1897.
which are bound by no law and which are the spontaneous utter¬
ance of inspiration, is not exempt from the most diligent correction
and arrangement, of which Alexander Pope is a famous illustra¬
tion.
By a most wise determination politics and theology are alike
excluded from our proceedings here ; it will therefore be dis¬
tinctly understood that it is in a purely literary sense that I allude
to the translation of the Bible in the reign of King James I. as the
standard of English composition on which great writers from that
day to this have formed their style. The exquisite balance of
words ; the strength and dignity of expression ; the grace and
flow of innumerable passages and whatever goes to the creation of
high literature, will be found crystallised there.
From this inexhaustible source of illustration I will but refer
you to a passage in the oldest dramatic poem in existence — the
Book of Job. It begins with — “ Surely there is a vein for the
silver, and a place for gold where they fine it. There is a path
which no fowl knoweth, and which the vulture’s eye hath not seen.
But where shall wisdom be found ? and where is the place of under¬
standing ? ” Man cannot tell, nor the depth, nor the sea. Gold
cannot buy the secret. Destruction and death have heard its fame,
but only with the hearing of the ears. A higher power alone can
give the answer. Men of eminence and judgment have considered
the wording of the translation faultless. Specially in the time of
Addison, but also throughout English literature, you meet with
treatises on Style. I prefer to illustrate the subject by examples.
Every writer, be he humble or otherwise, knows the crucial
difficulty of the opening sentence.
There he sits musing, not so much what to write, as to how the
matter should be introduced.
“ Sir,” said one to Dr. Johnson, “what should be done? should
an author wait for inspiration ” ?
“ He should sit down doggedly at his desk and pound at his
manuscript,” was the reply.
Some plunge abruptly into their story like Charles Dickens.
“ Marley was dead to begin with. There is no doubt whatever
about that ”• — and so on. “ You will therefore permit me to repeat
emphatically, that Marley was as dead as a door-nail.” [Opening
of ‘ Christmas Carol.’] Edmund Burke used this expedient with
admirable effect ; one of his most elaborate orations began with :
“ Gentlemen, I decline the election.”
Charles Kingsley’s ‘ Hypatia ’ opens with descriptive scenery ;
Mrs. Humphrey Ward does the same in ‘Marcella,’ and many
novelists follow suit. George Eliot in ‘ Middlemarch’ describes her
heroine in the first line ; while Sir Walter Scott not seldom gives
reams of introduction before you well know what he wishes to
relate.
One of the finest paragraphs in the English language will be
found in the opening sentence of Kinglake’s ‘Eothen’ ; one of the
most laboured and characteristic in that of Dr. Johnson’s ‘ Rambler.’
This is how he describes “ Good morning.”
“ The difficulty of the first address on any new occasion is felt
by every man in his transactions with the world, and confessed by
the settled and regular forms of salutation which necessity has
introduced into all languages. Judgment was wearied with the
perplexity of being forced upon choice, where there was no motive
to preference ; and it was found convenient that some easy method
of introduction should be established, which, if it wanted the
allurements of novelty, might enjoy the security of prescription.”
“Had you to write about the sea, Sir,” said Goldsmith, “you
would make all your fishes talk like whales.”
Many writers reserve their full powers for the ending of their
books, and the most exquisite of their conceptions immediately
precede the word Finis ; of late, a school called the Decadents,
wind up with a trivial and unmeaning sentence which has little or
no connection with the subject. This is supposed to be natural
and the waywardness of genius.
American authors however, especially in the short story, are
extremely happy in contriving an unexpected ending, of which
Mary E. Wilkins, in ‘ An Honest Soul,’ is a good example. But
should you desire specimens of the art of literary composition, as
shown in concluding paragraphs, I would instance ‘ The Cloister
and the Hearth,’ by Charles Reade ; ‘ Zanoni,’ by Bulwer Lytton ;
and the last words in ‘ Vanity Fair,’ by Thackeray.
I dare not omit in a notice on style however brief, to mention
three modern writers (two of them belonging to our own day), who
are masters of the art of composition : Charles Lamb, Rudyard
Kipling, and Robert Louis Stevenson.
I have reduced this bit of the subject to its barest outline, still,
April 3, 1897]
PHARMACEUTICAL JOURNAL.
293
it will be asked, whither does all this drift ? Are we as pharma¬
cists, burning to become great writers, or do we seek for literary
renown ?
We wish to have an intellectual standard not lower than the
artisan who crowds our evening classes ; like him to be able to
speak so as to be listened to with pleasure, and to write upon our
own subjects in a way to enlist the sympathetic interest of the
reader.
Let the pharmacist be advised not to confine himself to his
immediate surroundings, but in his leisure hours to read all sorts
and conditions of books, serious and amusing ; of sterling merit or
in lighter vein — thus he will widen his vocabulary (a matter of
infinite importance) and immeasurably increase his capacity for
clothing his ideas in words.
I now leave the literary side of the question and come straight
down to a few practical suggestions which may be called the
working formulae of composition.
Suppose you are about to write an essay, a paper or a book, then
let me, without wounding anyone’s susceptibilities, say just a
word on the art of marking the divisions of a sentence by means of
conventional signs called
Punctuation.
The comma [,] is not infrequently used with a too liberal hand.
“ Be sparing of the pepper-box,” was the advice of an old printer
at Beaufort Buildings.
Chambers in his ‘ Encyclopaedia’ has the same remark : “ Commas
are too often held in profound contempt, being scattered at random
amongst the words as if from a pepper-box ” — to which is added,
‘ ‘ Let the first and foremost aim be to bring out the meaning
clearly and unambiguously, in so far as this can be done with the
help of stops. Use commas and semicolons sparingly, especially
commas ; use them indeed only when absolutely necessary.”
Again, observe this standard rule :
“If the relative sentence is entirely subordinate to the main
sentence, or if it gives additional information, separate it by a
comma or commas ; if, on the other hand, it belongs essentially to
1 he structure of the thought expressed by the main sentence, put
no comma.” It is desirable that the comma whenever inserted,
should stand in its right place, else strange things may happen to
the text.
The curate who read — “ He saw in a vision, evidently about
the ninth hour of the day ” — was not happy in observing this rule.
‘ ‘ A man going to sea his wife, desires the prayers of the con¬
gregation ” suggests an unnecessary precaution. Put the comma
after sea, and all is well.
The Scotch version of a psalm, incorrectly punctuated, is said
once to have excited more surprise than devout impression : —
The Lord will come and he will not.
Be silent but speak out.
Delete the full stop and insert a comma after silent, and piety
regains its own.
The punctuation of the word “and” has always been a
disputed point — in connecting two words, even diametrically
opposed such as ‘ ‘ good and evil ” there is no comma ; when more
than two words are thus connected, practice varies. The phrase
“ good bad and indifferent ” is punctuated as fancy dictates. Follow
the instructions of your editor ; but where “and” is emphatic,
the separating comma is indispensable as in the sentence from
‘Zanoni’ — “ I return but to love, and youth, and hope.”
What shall we say of the sign for et csetera [&c.] placed at the
end of a sentence ? It is specially dear to pharmacists and young
writers. Unless it gives further definite information which it
seldom does, omit it altogether.
I have had the honour to pass many books through the press,
and in very rare instances has this sign been retained.
The exception is when its omission would limit the sense of a
passage, as for instance when part of a quotation only is given, or
an enumeration is obviously incomplete.
The colon [:] introduces something said, a speech or long
quotation ; the semicolon [;] subdivides parts of a sentence
complete in themselves, the sentence itself not being completed ;
the diaeresis [ae] consists of two dots placed over one of two vowels,
as in aerial, to show that both are sounded ; there are two brackets,
the curved lines ( ) used for an explanatory bye-remark ; and the
straight angular lines [ ] chiefly employed to mark reference. The
use of inverted commas to indicate something spoken or quoted, is
familiar, and this brings us to a full stop, in press correction a
dot within a circle 0 so.
(To be continued.)
NEW IDEAS.
A SIMPLE STERILISER.
A simple, efficient, and cheap appliance for sterilising milk
or other food in small quantities for the use of infants or invalids,
has been invented by Mr. J. A. Eorret, of Edinburgh, and is
intended to destroy any pathogenic organisms which milk may
contain when it reaches the consumer. The steriliser is thoroughly
tinned outside and in after it is made, the joints being thus much
less liable to corrosion by rust than is the case with ordinary tinned
ware. The vessel containing the milk, being surrounded by steam,
is subjected to definite temperature (100° C. ), and the boiling being
continued for a specified time, the temperature of the milk is
raised and maintained sufficiently high — from 70° to 80°- — for the
purpose of sterilisation. The steriliser is so made that the different
parts are easily made thoroughly clean, a very important matter
in the case of any vessel for milk or milk-food. The milk may be
stirred without removing the lid by turning the projecting rod.
A B C
Forret’s Steriliser. — A, outer vessel ; B, inner do., witli lid removed ;
C, steriliser, complete.
To use the steriliser, water is poured into the outer vessel
to the depth of about an inch and a half, the inner vessel
replaced, and the apparatus heated over a fire or gas-stove.
When the water boils remove the lid and pour a pint of milk
into the inner vessel (of the one-pint size) then replace the lid
and continue the boiling for seven minutes ; remove the steriliser
from the fire and allow to stand for about fifteen minutes, then set
the vessel containing the milk in a cool place till required. Boiling
should be continued for seven minutes for one pint of milk, whether
in the large or small steriliser ; for two pints continue the boiling
for twelve minutes ; and for three pints fifteen minutes. To
prevent the separation of cream the milk should be stirred fre¬
quently while it is on the fire, and until it is nearly cold. It should
also be stirred before any is poured out for use. After using the
steriliser, disconnect the stirrer and thoroughly clean and dry the
different parts, especially the inner vessel, the lid, and the stirrer.
The steriliser is made in two sizes — for one pint and three pints —
retailing at 3.s. 6 d. and 4s. 6 d. each respectively. They are supplied
wholesale by Messrs. J. F. Macfarlan and Co., of Edinburgh
and London.
PHOTO-MICRO LANTERN SLIDES.
Lantern slides, illustrating botanical and zoological subjects as
seen when highly magnified, are prepared by Mr. Geo. T. Phillips,
who is devoting special attention to the requirements of lecturers
and others interested in micrography. He has a practical knowledge
of botany and zoology, and knows, therefore, what are the distinctive
features of objects to bring out, thus rendering the slides of greater
value for educational purposes than would otherwise be the case.
He undertakes to prepare slides from lecturers’ own objects, or to
supply complete series of slides, and he also offers unmounted photo¬
graphic prints of typical stem and root sections, etc., for students
to paste in their note books. Specimens that have been submitted
display great merit and show that they have been skilfully pre¬
pared. Mr. Phillip’s address is Rosneath, Crown ' Hill, Upper
Norwood, S.E.
294
PHARMACEUTICAL JOURNAL.
[April 3, 1897
PROCEEDINGS UNDER THE PHARMACY ACTS-
RECENT CASES IN SCOTLAND.
Prosecution at Hamilton.
At the Sheriff Court House, Hamilton, on Friday, March 26, the
case of Bremridge v. John Miller, assistant in the shop of Dr. A.
Lees, Glasgow Road, Burnbank, Hamilton, came before Sheriff
Davidson. The accused was charged with selling laudanum, on
November 3, 1896, and red oxide of mercury as an ingredient in
an ointment, on February 12, 1897, to an agent of the Registrar.
Mr. Louden, solicitor, Hamilton, instructed by Mr. P. Morison,
S.S.C., Edinburgh, appeared for the prosecutor. Mr. Hay,
solicitor, Hamilton, appeared for the defender, who pleaded not
guilty.
Mr. Rutherford Hill produced the registers for 1896 and 1897,
proving that the accused was not registered. He also produced
the bottle of laudanum and the box of ointment, which he had
analysed. The bottle contained about 2 fluid drachms of laudanum,
and the ointment about 30 grains of red oxide of mercury. The
box bore no label, and all the provisions of Section 17 had been
disregarded in the sale.
Cross-examined by Mr. Hay, the witness said he did not analyse
the other constituents of the ointment, but separated the red
oxide of mercury in the free state. There was an antidote to
poisoning by mercuric oxide, but he did not look for any in the
ointment. He did not think the presence of an antidote would
affect the question of a sale of poison. The other constituents
appeared to be merely a fatty basis. Red oxide of mercury was
in the Poison Schedule, but it did not say “ Red oxide of mercury
and its preparations ” as in the case of opium, etc.
The Sheriff : Could there have been an antidote along with the
red oxide of mercury which might have neutralised its poisonous
effects ?
Mr. Rutherford Hill : There might ; but though I did not look
for an antidote, the one I am thinking of could not be present. I
mean white of egg. The fatty basis was soluble in ether, leaving
nothing but red oxide of mercury. White of egg is insoluble in
ether, and therefore could not be present. I may add that mercuric
oxide is a very virulent poison, and it is very doubtful if any anti¬
dote like white of egg would successfully overcome its poisonous
effects with such a quantity as was sold here.
Alexander Spence and Joseph Tait proved the sale of the
poisons.
Mr. Louden : That is my case. The offences are clearly proved,
and I ask for the penalties.
Mr. Hay said, with regard to the first offence, he did not think
it was properly proved. Only one witness was in the shop, and
this was only corroborated by a witness who was said to look in
from the outside. Considering that these witnesses were pro¬
fessionally employed to get up evidence, he did not think that was
at all sufficient proof. Mr. Hill even seemed to have a doubt, or
why did he try to get another charge in February ? The
same applied to the second charge. He also complained
of delay in bringing the first charge, though that did
not apply to the second offence. This was an offence
under a special statute, and they were bound by the letter of the
Schedule. He pointed out that while red oxide of mercury was in
the Schedule a preparation of red oxide of mercury was not men¬
tioned in the Schedule, and that was what was sold here. He
would also direct his Lordship’s attention to the remarks made by
Sheriff Mair in the Airdrie Sheriff Court the other day, which he
thought were rightly applicable to this case and to the action
generally of the Pharmaceutical Society. He did not think they
were at all too strong. He was entitled, and he intended to take
advantage, of every technicality in defending a case of this kind,
and he did not think the charges had been proved.
Mr. Louden said his Lordship would see that red oxide of
mercury, though not in the original Schedule to the Act, was
added to the Schedule by an order in Council, which he now sub¬
mitted, made in pursuance of the Act. There was nothing in the
defence that the article sold was a preparation of red oxide of
mercury. On this point he drew his Lordship’s attention to the
judgment in the Armson case (2 Q.B.D., 1894, p. 720), in which the
Master of the Rolls said : “ It is clear that when poison is put into
a medicine, and a person sells the medicine, he sells the poison that
is in it. Then he has sold poison.”
The Sheriff said he was not called upon to express any opinion
as to the policy of the Pharmacy Acts, and he had no intention of
doing so. He had no doubt that the poisons mentioned were sold
by the accused, whom he therefore convicted of both charges, and
imposed a modified penalty of £1 for each offence, with £2 8*\ 8 d.
of expenses.
Prosecution at Edinburgh.
At the Sheriff Court House, Edinburgh, on Monday, March 29,
1897, the case of Bremridge v. Walter Stanley Murdoch, assistant
to George Christie, Chemist, Newton Grange, Midlothian, came
before Sheriff Maconochie. The accused was charged with selling
cantharides in a fly blister, and belladonna in a plaster to an agent
of the Registrar on February 13, 1897.
Mr. P. Morison, S.S.C., appeared for the prosecutor.
Defender pleaded guilty to the first charge, and prosecutor
accepted the plea and withdrew the second charge on the ground
that there was virtually one sale of poison, though two poisons had
been sold at the same time.
Mr. Morison explained that the accused’s employer had a chemist’s
shop at Gorebridge, and had openedabranchshop atNewton Grange,
where he put the accused in charge. There seemed to be a popular
delusion that if a qualified chemist or doctor was the owner of the
shop an unqualified person might be put in charge of it. It had
been decided in the Tomlinson case in the High Court of J usticiary
recently that this was an offence in the case of a doctor’s shop.
This was a case of a chemist’s shop, and it was necessary to impose
a penalty to put a stop to a practice which nullified the protection
to the public which the Act was intended to secure.
The Sheriff asked if there had been cases of this kindbefore. The
cantharides was in a fly blister and the belladonna in a plaster. It
did not seem likely that people would take such things.
Mr. Morison said they had had exactly similar cases before, and
there was the famous Maybrick case, in which the arsenic was
extracted from fly-papers. He was also informed by Mr. Hill
that the cantharides in the fly blister was in such a condition that
it could be directly used for criminal purposes.
The Sheriff : I am quite satisfied, and I impose a modified penalty
of £1 and £2 of expenses.
Prosecutions at Glasgow.
At the Sheriff Court House, Glasgow, on Wednesday, March 31,
a number of cases instituted by the Registrar under the Pharmacy
Acts, 1852 and 1868, Mr. Bremridge, came before Sheriff Tyfe.
Mr. E. T. Salvesen, advocate, instructed by Messrs. Martin
and Barrie, solicitors, Glasgow, for Mr. P. Morison, S. S. C.,
Edinburgh, appeared for the prosecutor. Mr. Thomson and Mr.
Mackay, solicitors, appeared for Dunlop and Walls respectively.
In the case first taken, Andrew Brown Gilmour, an assistant in
the shop of Dr. Clark, 324, Rutherglen Road, Glasgow, was
charged with two offences for selling laudanum and Powell’s balsam
of aniseed on November 28, 1896, to an agent of the Registrar. —
Defender was fined ten shillings for each offence, with two pounds
expenses.
The second case was that of Andrew Dunlop, an assistant in the
shop of Dr. Wilson, 470, Paisley Road, Glasgow, who was charged
with two offences for selling laudanum and Powell’s balsam of
aniseed on November 28, 1896, to an agent of the Registrar. —
Defender pleaded guilty, and was fined ten shillings for each
offence, with two pounds expenses.
The next case was against Robert Adams, an assistant in the shop
of Thomas McKee, junior, 386, Cumberland Street, Glasgow, who
was charged with one offence for selling chloroform and morphine
in a mixture dispensed by him, and opium in pills on November 28,
1896, to an agent of the Registrar. — Defender was fined ten
shillings, with twenty shillings expenses.
In the fourth case heard, John Walls, an assistant in the shop
of J. and S. Robertson, grocers, 467, Cathcart Road, Govanhill,
Glasgow, was charged with one offence for selling a bottle of
Dr. J. Collis Browne’s Chlorodyne, on November 21, 1896, to an
agent of the Registrar. — Defender pleaded guilty, and was fined
ten shillings, with twenty shillings expenses.
The last case was against David Hunter, an assistant in the shop
of Dr. Taylor, 74, Nelson Street, Glasgow, who was charged with
one offence for selling red oxide of mercury as an ingredient in an
ointment, on November 28, 1896, to an agent of the Registrar. —
Defender was fined ten shillings, with twenty shillings expenses.
April 3, 1897]
PHARMACEUTICAL JOURNAL.
295
PARLIAMENTARY NOTES AND NEWS-
The Merchandise Marks Committee had a field-day on the
22nd ult. , when Sir Courtenay Boyle, Permanent Secretary of the
Board of Trade, was examined in the hope of eliciting damning
evidence against the Bill of 1887. But the witness did not give
much encouragement to the advocates of Protection, who strive to
improve the occasion on committees of this kind. Sir Courtenay
thought that the Act of 1887, on the whole, had been
of advantage in protecting the consumer against false
information, and that though the evasions were many, it was
not so much the fault of the law as the apathy of traders. The
Act is strong enough, the witness said in effect, it only needs those
interested to put it into force. The Board of Trade certainly does
take up cases, but they have to be very strong cases, for, as it was
pertinently pointed out, it would not do for the State to take
proceedings against individuals and not to succeed. The witness
also knocked the bottom out of the ruined -by-foreign-competition
argument by stating that he was unaware of any evidence show¬
ing that the effect of the Act had been to transfer the carrying trade
to foreign ships. Whatever increase there might be in the tranship¬
ments from foreign ports to British Colonies was, he thought, due
to other causes. In short, beyond giving the foreigner a gratuitous
advertisement, the Merchandise Marks Act seems to have done
very little harm. It was suggested that “Made in England”
should be stamped on British goods in place of marking foreign
goods with the port of origin, but Sir Courtenay Boyle admitted
that he foresaw difficulties. For instance, how could one prevent
unstamped imports being subsequently marked “ Made in
England ” ? The evidence constituted an object-lesson on the
futility of attempts to suppress commercial competition.
The Professorship of Botany in the University of Edinburgh
if the subject of a short Bill introduced by the Lord Advocate (Rt.
Hon. A. Graham Murray) and Mr. Anstruther (St. Andrews’
Burghs), a Lord of the Treasury. It appears that there are two
chairs of botany in the University and a keepership of the Royal
Botanic Gardens. One person usually occupies the three posts,
in fact, the present holder is one of the Pharmaceutical Society’s
honorary members, and a member of the Board of Examiners in
Scotland (Professor Bayley Balfour). The anomaly which the Bill
seeks to remedy arises from the fact that two of the appointments
are in the gift of the Crown, and one in the patronage of the
curators of the University, and there is no agreement between
the Crown and the University securing a continual union of the
three posts. As union is desirable, both on economic and other
grounds, the Bill transfers the patronage of the University Pro¬
fessorship to the Crown, the University receiving in return the
right of presentation to the Professorship of Natural History,
hitherto exercised by Her Majesty.
Mr. Timothy Healy is a distinguished member of the Irish Bar,
which is equivalent to saying that his abilities as a lawyer are of
the very highest order. He has for a time turned from purely
Irish matters to examine critically the recent Order of Council relat¬
ing to carbide of calcium. The result of the examination is a doubt
in Mr. Healy’s mind whether the law officers of the Crown were con¬
sulted as to the applicability of the Petroleum Acts, which deal with
a particular liquid substance to a solid body not contemplated in
those Acts. The Attorney- General is to be asked to explain, and
will doubtless do so as we are going to press. Mr. Healy’s law is
brilliant, but the terms of his question, which we have not the
space to reproduce, do not lead us to rank him as an expert on the
properties of carbide.
Position of Private Members’ Bills. — Progress in this con¬
nection is but a bare record of postponement. Boiler Inspection
and Registration is relegated to Wednesday, May 5, for its second
reading ; Midwives’ Registration is tabled for April 8, and the
hopes of the promoters of the Plumbers Registration Bill have
not been raised by the further adjournment of the
second reading of the measure to April 30. Other Bills,
the fortunes of which we are following, are in similar plight. Mr.
Kearley’s Food and Drugs Bill and Mr. Duncombe’s Half -Holiday
Bill ought to come on this week, but considerable emphasis may
be made on the “ ought.” The Early Closing Bills are not to come
on the paper again till April 27.
PHARMACEUTICAL SOCIETY.
SCHOOL OF PHARMACY SESSIONAL PRIZE
EXAMINATIONS.
INORGANIC CHEMISTRY AND PHYSICS.
Professor Collie.
Thursday, March 25. — 10 a.m. to 1 p.m.
1. Describe fully how a specimen of pure acetic aldehyde might be prepared,
also how the following substances could be produced from it (1) Lactic acid,
(2) secondary butyl alcohol (methyl ethylcarbinol), (3) paraldehyde and metalde-
hyde, (4) chloroform.
2. Give a brief history of the word “ acid."
3. Write a short account of the properties and chemical constitution of the
three sugars — cane sugar, grape sugar, fruit sugar.
4. Explain how the coefficient of expansion of mercury has been determined.
Why are the results of great importance ?
5. What is — (1) Selective absorption, (2) fluorescence, (3) calorescence ? Point
out any simple phenomena which may be deemed analogous to them.
6. What are “secondary batteries”? Describe the construction of one, and
point out how its action is connected with the phenomenon known as “ polarisa¬
tion ” in a simple battery.
ADVANCED COURSE OF PRACTICAL CHEMISTRY.
Professor Collie.
Friday, March 26. — 10 a.m. to 1 p.m. , and 2 to 5 p.m.
•1. Analyse the solution. (1) Determine what the substance is that is dissolved.
(2) The amount per litre of the substance, by two different methods.
2. Determine the nature of the compound given, what impurity is present, and
the percentage amount of that impurity.
ADVANCED COURSE OF BOTANY.
Monday, March 29. — 10 a.m. till 1 p.m..
Professor Reynolds Green.
[Only three questions to he answered.']
1. Give an account of the peculiarities of the reproductive mechanisms of o
of the Hydropterideae. How is this group sub-divided ?
2. Indicate the relationships that exist between plants of the Natural Order
Ranunculacese and Papaveraceae.
Explain as far as you can the occurrence of irregular flowers in the former
group, and point out the purposes of the structures they present.
3. Describe the method of utilisation of the reserve materials deposited in a
grain of barley, stating what changes they undergo during the process of
germination.
4. Give a general sketch of the classification usually adopted for the Alga;, and
point out the leading features of the principal groups.
ADVANCED COURSE OF PRACTICAL BOTANY.
Monday, March 29. — 2 to 5 p.m.
Professor Reynolds Green.
1. Make microscopic preparations to illustrate the structure of A. Moun
them in glycerine. Sketch your preparations and say what each indicates.
2. Refer the specimens B, C, D to their places in the natural system of classifi¬
cation, giving your reasons.
3. Identify and briefly describe the three microscopic preparations E, F, G.
ADVANCED COURSE OF MATERIA MEDICA.
Tuesday, March 30. — 10 a.m. to 1 p.m.
Professor Henry G. Greenish.
1. Identify the sample of Starch A supplied to you, and report upon its purity.
2. The powder marked B is said to be powdered senna. Is that the case ?
Give reasons for your answer.
3. Examine the bark given you. Point out features that may have a diagnostic
value. Prepare, describe, and make a diagrammatic sketch of a radial section,
leaving the section mounted in glycerin for inspection.
ADVANCED COURSE OF MATERIA MEDICA.
Tuesday, March 30. — 2 to 5 p.m.
Professor Henry G. Greenish.
1. Describe the varieties of Coca leaves known as Bolivian and Peruvian.
What alkaloids do they contain ? How may the drug be assayed ?
2. Give a short dfccount of the constituents of rhubarb ; compare them with
those of senna.
3. By what characters may the leaves of Digitalis purpurea he distinguished
from all others likely to be mistaken for them ?
4. What are the principal forms in which calcium oxalate occurs in the
vegetable cell ? Mention official drugs in which these forms are found.
5. What do you understand by the terms, “oil-cell,” “oil-gland,” “oil-duct”?
Why is this distinction of importance to the pharmacognosist? Give illustra¬
tions taken from official drugs.
296
PHARMACEUTICAL JOURNAL.
[April 3, 1897
THE STUDEHTS’ PAGE.
THE FLOWERS OF APRIL.
The number of plants coming into flower will now increase
so rapidly that it is impossible to do more than give the names of
the more interesting in the space available in these columns.
During the summer months, therefore, the list will be given in the
form of a calendar, and explanatory notes given only at the request
of any of our readers who find a difficulty in understanding their
structure or morphology. The following letters attached to the
names will give the following indications : — G., to be found in gar¬
dens ; B. G. , to be looked for in botanic gardens ; E. , exceptional
in some of its characters. Most of those marked E. are explained
in the list of exceptions to the natural orders, in Holmes’ ‘ Botanical
Note-Book.’
*Adoxa moschatellina
Ajuga reptans
*Alchemilla vulgaris
Alliaria officinalis
* Anemone pulsatilla
A nthoxanthurn odoratum
Arum maculatum,
Asarum europceum, B.G.
Berberis aquifolium, G.
BvjXUS sempervirens, G.
*Caltha palustris
Cardamine pratensis
Corydalis solida, B.G.
Dielytra spectabilis, G.
Epigoea repens, B.G,
Forsythia suspensa, G.
Fraxinus excelsior
Fritillaria imperialis, G.
,, meleagris
Gaultheria procumbens, B.G.
Jeff 'ey sonia diphylla, B.G.
Lathrcea squamaria
Lathyrus macrorhizus
Luzula pilosa
Myrica gale
Nepeta glechoma
Orchis mascula
Oxalis acetosella
Paris quadrifolia
Petasites vulgaris
Populus nigra
Primula veris
Prunus amygdalus, G.
Pulmonaria officinalis, Q.
Ranunculus Imlbosus
Rosmarinus officinalis, G.
Ruscus aculeatus
Salix alba [B.G.
Sanguinaria canadensis
Saxifraga crassifolia
Scrophulariavernalis, BG
Ulmus campestris
Valerianella olitoria •*
Vinca minor
Viola odwata
NOTES ON THE PHARMACOPOEIA.
Calx Chlorinata. — Popularly known as “ Chloride of Lime.”
It is a mixture or a weak compound of hypochlorite and chloride of
calcium with slaked lime, the latter never being wholly converted
into the chlorinated compound by the action of chlorine. The
formula Ca2C10, CaCl2 would yield 55 -9 per cent, of chlorine by
the action of acids ; the official requirements are satisfied by a
product yielding 33 per cent, of chlorine — the term “available
chlorine ” refers to the amount of chlorine evolved by the action of
acids.
(i. ) Ca2C10 + CaCl2 + 2H2S04 = 2CaS04 + 2HC10 + 2HC1.
(ii.) 2HC10 + 2HC1 = 2HaO + 2C12.
The determination of the’chlorine is indirect, i.e., it isliberatedinpre-
sence of potassium iodide, and the equivalent quantity of iodine
(Cl, 35 '5=: I, 127) displaced by the chlorine determined by titra¬
tion with sodium thiosulphate solution. This is the most conve¬
nient way of determining free chlorine, the end reaction between
iodine and sodium thiosulphate (disappearance of the brown
colour of free iodine, or blue, if starch be employed) being sharply
distinguished. In iodine titrations it is advisable not to add starch
mucilage until nearly all the iodine has been used up, i.e., when
the brown colour has almost disappeared. If the starch be added
at first when there is a lot of free iodine, a blackish colour is pro¬
duced and the end reaction is not so sharp. Some operators do not
use starch at all, but used as described above, the termination of
the reaction is more apparent since the blue colour of iodide of
starch is more intense than the brown colour of an equivalent
quantity of iodine. Note that the action of chlorine (and bromine)
upon thiosulphate of sodium is quite different to that of iodine —
2Na2S203 + 21 = 2NaI + Na2S406.
In presence of water, chlorine is an energetic oxidising agent, and
converts the thiosulphate into sulphate, sulphur being deposited —
SOME NOTES ON CRYPTOGAMS.
There are two genera of fresh-water algas that may be studied
during this month. On damp spots in fallow fields Vaucheria
terrestris may be found in dense green patches of one or two inches
in diameter. V. sessilia forms looser patches of similar character.
The first, represented in Fig. 1, has the antheridium on the same
stalk as the oogonium. The latter has the antheridium placed
between two sessile oogonia. In shady pools or ponds Spirogyra
porticalis (Fig. 2) may now be found in conjugation. In the Vau¬
cheria it should be noted that the whole plant is a branched cell, the
only dissepiment usually seen being that which cuts off the
oogonium or antheridium from the rest of the plant. In Spirogyra
it should be observed that the chlorophyll band is single in this
species, that the cell divisions are flat, and the oogonia are oval.
Fig. 1. Fig. 2.
Reverting to the gemma; of Lunularia (see ante, p. 276),
which, on account of their greater size, are the most conve¬
nient for examination, they show a disk-like form with
two or more lateral indentations and a short stalk or a scar
at the base, where they were attached to the thallus. The body
is composed chiefly of chlorophyll-parenchyma, with a few single
cells containing oil bodies. The outer portion is only a single cell
in thickness, whilst the centre is a solid structure. After separa¬
tion from the thallus certain superficial cells develop into rhizoids,
and the gemma grows into a new thallus. Lunularia, in common
with certain other liverworts, possesses peculiar stomata, which
differ considerably in structure from those found in other plants,
and should be examined carefully under the microscope. To the
naked eye they appear as minute dots on the surface of the thallus.
Na2S203 + Cl2 + H20 = Na2S04 + 2HC1 + S.
Cerii Oxalas. — Cerium, in the course of analysis, is precipitated
with the metals of the iron group, i. e. , its chloride is soluble in
water, it does not form a sulphide insoluble in weak acid, but
insoluble cerium hydrate is precipitated by ammonia. Cerium
occurs in nature associated with lanthanum and didymium, and
the reactions and solubilities of the various salts of these three
metals are so similar that their separation in an absolutely pure
condition is rendered very difficult ; consequently cerium oxalate,
as found in commerce, contains small quantities of didymium and
lanthanum oxalates. If cerium oxalate be quite pure the residue
of cerium oxide after ignition would be yellow — the reddish-brown
colour mentioned in the Pharmacopoeia is due to didymium oxide.
The metals of the cerium group are distinguished by the
formation of insoluble double sulphates with potassium.
Iron, aluminium, and chromium form double sulphates soluble in
water. Alumina, as an impurity, is detected by boiling with
otash, which precipitates cerium hydrate ; the aluminium hydrate
eing soluble in this reagent, is looked for in the filtrate in the
usual manner — addition of ammonium chloride, which effects the
substitution of free ammonia, in which aluminium hydrate is
insoluble, for potash.
NH4Cl + KHO = KCl + NH4HO.
Ignition of a metallic oxalate may result in production of —
(i.) a carbonate (calcium, potassium).
(ii. ) an oxide, if the corresponding carbonate be easily decom¬
posed by heat (iron and cerium), or — -
(iii.) metal, if the carbonate and oxide are both decomposed at
high temperature (silver).
Chloral Hydras (see ante, p. 276).-— After warming with
caustic potash to decompose the chloral into formic acid and
chloroform, add a small quantity of aniline. A very penetrating
and nauseous odour due to phenyl iso-cyanide is given off.
C6H5NH2 -i- CHC13 = C6H5NC + 3HC1.
This reaction is characteristic of primary amines, i.e., bodies
derived from ammonia by replacement of one hydrogen atom by a
radicle. Secondary amines are bodies having two hydrogen atoms
similarly replaced [NH(C2Hg)2], and tertiary all three [N(02H5)3].
Codeina. — Codeine is distinguished from morphine by its
solubility in ammonia and insolubility in potash or lime water.
Morphine gives a red colour with nitric acid — -codeine does not.
The latter also gives no blue colour with ferric chloride, and does
not liberate iodine from iodic acid.
April 3, 1897]
PHARMACEUTICAL JOURNAL.
297
Pharmaceutical Journal.
A Weekly Record of Pharmacy and Allied Sciences.
ESTABLISHED 1841.
Circulating in the United Kingdom, France, Germany,
Austria, Italy, Russia, Switzerland, Canada, the
United States, South America, India,
Australasia, South Africa, etc.
Editorial Office: 17, BLOOMSBURY SQUARE, W.C.
Publishing at\d Advertising Office : 5, SERLE STREET, W.C.
LONDON : SATURDAY, APRIL 3, 1897.
THE CHEMISTS REMUNERATION.
From time to time the subject of chemists’ charges crops
up in the lay press, some unhappy correspondent
feeling impelled to write to the editor to complain that he
has paid a few pence more or less for an article in one phar¬
macy than in another. The greatest excitement, perhaps, is
displayed when a prescription has been dispensed at
different rates, and the original declaration against a supposed
imposition is speedily capped by harrowing tales from
all sorts and conditions of people bearing upon the tendency
displayed, as the writers often profess to think, by chemists
and druggists generally, to fleece them whenever they have the
chance. The inevitable protest from a member of that, for
the time being, much-abused class appears sooner or
later, but if it should happen to be published whilst
public interest in the matter is still maintained,
the writer may look forward with every confidence
to see his facts denied and his arguments derided or ignored.
And then, as some other grievance must, in turn, be aired in
the press, the topic of chemists’ charges disappears once more
into the background , to be served u p afresh with unabated energy,
enthusiasm, and perchance virulence, at some future date.
The net result of the discussion is usually that a few more
people than formerly begin to distrust those in whom they have
previously been accustomed to repose every confidence, but
no one — if w7e except the conductors of the papers, by whom
probably the whole affair has been arranged to fill a gap
during the dull season — is really satisfied with the outcome
of the wordy warfare.
Now, though it is undeniable that chemists’ charges do
vary, it cannot be acknowledged that the public has the
least ground on which to base a grievance respecting the
matter. In what trade or profession in this country are the
charges uniform for articles of the same class or work of the
same kind 1 Grocers, butchers, shoemakers, booksellers,
doctors, lawyers, artists, and members of every other class
that can be mentioned, base their charges mainly on the
purchasing capacity of their customers and clients, and the
same individual does not expect to find the purchasing power of
his money of equal value in all districts. Contrast Whitechapel
and Regent Street for example, or the lower class districts of
any town and the aristocratic suburbs of the same. Would
anyone anticipate identical results on expending a given
amount in either case, elsewhere than in pharmacies 1
Certainly not, and it is difficult to see, therefore, why
chemists and druggists should be singled out as the sole ex¬
ceptions to this general rule. Why should the chemist and
druggist be debarred from exercising the right to stipulate
his own terms for services rendered 1 There is no apparent
reason, and of course there is no prospect of the attempt being
made to debar him. But it is well to weigh the matter carefully,
and then decide to approach the question of variation in prices
with a determination not to submit to outside dictation,
rather than to excuse the prevailing custom in a semi-
apologetic manner.
The chemist and druggist, for instance, must continually
bear in mind — especially in dealing with prescriptions —
that he is entitled to charge for professional or special tech¬
nical services rendered Where such special services are
rendered by any other class, a due equivalent is
invariably demanded as a recompense, and the chemist
and druggist would be pursuing a suicidal policy
and neglecting his best interests if he were to
allow himself to be persuaded to regard all his busi¬
ness transactions from a purely commercial standpoint.
Further, when the matter is considered fairly, it will be
seen that one of the soundest commercial axioms is that
which insists upon the best possible return being
obtained for all services rendered. Successful professional men
act upon this principle — a wholly commercial principle — of
necessity, otherwise they would not be successful. To reduce
one’s terms because another charges less for similar
services would be absurd so long as the public is willing to
acquiesce in the higher terms. And, after all, the value of an
individual’s services is, more frequently than not, based upon
his own estimate of those services. Indeed, if that estimate
be formed after paying due regard to all the circumstances
of the individual case, it will in all probability approximate
so closely to the truth that the public will accept it readily.
But the main point to bear in mind is that, having
once taken up a decided stand in this matter, no one
should depart from it rashly, and if change be desirable,
it should be gradual— evolution rather than revolution
being the key to the situation.
THE PROPOSED NEW BYE LAWS.
Glasgow has spoken on the subject of the proposed
alterations in the byedaws and, in effect, has approved of
the suggested changes. We understand that opposition to
the increase in the registration fee is practically non-existent
amongst chemists and druggists in Glasgow, and that the
only bar to an expression of complete approval at the meet¬
ing held last week was the prevalence in the district of
a feeling that the period at which the increased fee is
intended to come into effect is too early. On that point,
however, the members of Council must be the best judges,
and our Glasgow friends who approve of the principle of the
proposed alterations should be content to leave the arrange¬
ment of details to their elected representatives. At Aber¬
deen, twenty-five assistants and apprentices have sagely
settled the financial affairs of the Pharmaceutical Society to
their own satisfaction, and expressed the opinion that an
increase in the registration fee is unnecessary. Birmingham
assistants, on the other hand, are reported to be of opinion
that the extra fee cannot help but be of benefit to the trade
at large, and that is probably what all chemists and druggists
in business will conclude, after considering the matter
calmly and without prejudice.
298
PHARMACEUTICAL JOURNAL.
[April 3, 1897.
ANNOTATIONS.
The Pharmacy Acts are being put in force in Scotland to an
extent which should satisfy every Scottish member of the Society
that he gets full value for his subscription. Moreover, the micro¬
scopical returns in the shape of fines and costs ought to convince
the most sceptical non - subscribing chemist and druggist
that the supposed surplus from his examination and registra¬
tion fee is badly needed, if the record of cases under the
Acts is to be maintained. Modified penalties seem to be
the rule in Scottish courts, the Sheriffs having apparently
cultivated the art of looking at money many times
before disposing of it, to an extreme and sometimes even exas¬
perating degree. The main point, however, is to maintain the
Statute to the fullest possible extent, and the representatives of
the Society in Scotland are to be congratulated upon the uniformly
successful issue of all the cases reported in this week’s Journal.
It is also satisfactory to find Sheriff Davidson (see p. 294) giving
utterance to the statement that he was not called upon to express
any opinion as to the policy of the Pharmacy Acts, and that he had
no intention of doing so. This is as it should be, and other Sheriffs
in Scotland should note the innate wisdom of this judicial statement.
Lime Juice and Glycerin has claimed another victim, Mr.
Thomas Mann, chemist and druggist, of Hampton Hill, having been
convicted and fined for selling a bottle of that compound alleged
to be devoid of glycerin and actually containing no lime
juice. The case was originally heard a fortnight ago (see
ante, p. 253), and then adjourned for the purpose of having a
sample of the preparation examined at Somerset House. The public
analyst had certified that it contained no glycerin and no lime
juice, but the certificate from Somerset House stated that
the sample contained glycerin to the extent of not more than
half or one per cent. The fatal oversight, therefore, proved to be
the omission of lime juice, and though defendant pleaded that the
preparation contained “ essence of limes,” the hearts of the magis¬
trates were hardened and they would not let him go, except on
payment of five shillings and costs. Thus was the law upheld, and
the intelligence of local authorities and magistrates once more
exemplified. But what, it may be asked, must people ask for who
really want such a preparation as Mr. Mann has been innocently
selling, never dreaming that it was either a food or a drug ?
The Plough Court Pharmacy records, as recently presented
in our pages, have attracted a considerable measure of attention
and, on account of its important bearing on the early history of
chemists and druggists, it has been thought desirable to reprint
the matter in pamphlet form. The reprints are now ready, and
copies may be obtained from the publishing office of the Journal,
5, Serle Street, W.C., at one shilling each, post free. The portrait
of William Allen and all the illustrations used to illustrate the
articles are reproduced in the book.
Poisoned by his Own Preparation, whilst suffering from a
weak heart, a Dunmow chemist died from syncope on Tuesday last
week. The preparation — “ chloronette ” — was a variant on chloro-
dyne, and appears to have contained prussic acid, which is now
usually omitted from chlorodyne, in addition to morphine and
chloroform. Deceased was over sixty, and had been in the habit
of taking “chloronette” to relieve palpitation. On the fatal day
he asked his son to give him a dose, and after swallowing part of
the half-drachm mixed for him, he became worse, and died within
a quarter of an hour. The medical evidence showed that morphine
and chloroform were most unsuitable things for deceased to take,
considering his state of health, and the case affords one more
instance of the dangers attending indiscriminate self-medication.
Public Analysts and Somerset House have once more dis¬
agreed, this time about adulterated olive oil. A Bottesford grocer
had sold oil which Dr. Bernard Dyer certified to contain twenty
per cent, of cotton oil. The sample referred to Somerset House,
however, was stated to contain no cotton oil, though twenty per cent,
of sesame oil was said to be present. The Leicestershire magis¬
trates who heard the case were therefore in a dilemma, but when
Dr. Dyer’s certificate was supported by three other analysts —
Messrs. Hehner, Bevan, and Cassall— the difficulty was somewhat
illogically met by a decision to impose no penalty. The report of
this case ought to occupy a prominent place in a digest of the
humours and curiosities disclosed during the working of the Sale of
Food and Drugs Acts.
The Proprietary Articles Trade Association held its first
annual meeting on Wednesday afternoon, and after one or two
slight attempts on the part of some who attended to kick over the
traces, the Chairman — Mr. W. Jones, of Birmingham — got his team
well in hand, and business proceeded apace. The annual report
and financial statement were as satisfactory as could be expected for
the first year’s working, and were duly adopted after the Secretary
had explained the position of affairs. Mr. Glyn -Jones was careful
to emphasise the fact, which too many are inclined to disregard,
that the Pharmaceutical Society, as such, cannot take any steps
in the matter of the regulation of prices. He suggestively re¬
marked, however, that members of that Council could individually
show their practical sympathy with the present movement without
involving the Council in their action.
The P. A.T. A. now Includes 2060 Retailers, and Mr. Glyn- Jones
asserts that all of those are determined to support its objects by
fair and legitimate means. It might be regarded, therefore, as a
factor to be reckoned with, and manufacturers who have not yet
joined the Association were warned of the probable results of their
inaction, the manufacture of proprietary articles to displace others
now on the market being indicated as a possible means of securin g
the desired end. It is needless to say that the proceedings were most
enthusiastic — the Association is not yet old enough to realise what
despondency means — and that everyone who attended seemed im¬
pressed with the brightness of the prospect that was presen ted to their
view. Such hopefulness is a healthy sign and, whatever may be
the outcome of the anti-cutting movement, there can be no doubt
of the value of the feeling which has induced so many chemists in
business to band themselves together and work for the common
good of their class.
The “ Eggs ” Producing “ Pharaoh’s Serpents ” would
hardly be regarded by most people as triumphs of the confec¬
tioner’s art, nor is the average seller of those articles likely to be
so foolish as to attempt to prove their innocuous nature by eating
them. The exception is held to prove the rule, however, and
Judge Lushington has had occasion to determine what damages
must be awarded to a person who seemed to think that what she
sold must needs be good to eat. According to the Lancet, a lady
confectioner purchased a number of farthing packets containing
these so-called “eggs,” and sold one of them to a child, whose
father tasted the contents of the packet and wisely expressed th e
opinion that they were nasty. The goods were returned accord-
April 3, 1897]
PHARMACEUTICAL JOURNAL.
299
ingly, but the confectioner, anxious to show that she sold innocu¬
ous things only, ate one of the “eggs” herself, regarding it as a
sweet, with the result that she was taken very ill and was medi¬
cally attended for several weeks. This was the ground of an action
against the dealers who supplied the “eggs,” and Judge
Lushington, deciding that there had been negligence on the part
of the defendants, gave judgment for the plaintiff for the
full amount claimed — fifty pounds.
Letters after Names have a wonderful fascination for the
public and, however meaningless, they may be depended upon to
produce a definite effect if only there be enough of them. Medical
quacks, in particular, appear to benefit by the credulity with
which such name appendages are received, and the Birmingham
Daily Gazette comments upon a case in point. A woman died
from failure of the heart’s action after receiving treatment at a
“ Homoeopathic and Magneto-Electric Institute,” the proprietor
of which is said to have induced the belief that he was a qualified
medical practitioner, by exhibiting a string of letters without
meaning after his name. As it happens, no connection could be
established between the man’s method of treatment and the
patient’s death, and though it is suggested that the Medical
Council could take proceedings against the much be-lettered
gentleman, it is to be feared that he will in no wise be dismayed
but proceed on his accustomed course of quackery as usual. And
the public will continue to worship letters !
Professor Koch, according to information received from Berlin,
has produced two new preparations or compounds of tuber¬
culin, and it is claimed that the German professor, after many
years of patient research, has this time discovered a sure means of
counteracting the dire effects of the bacillus of tuberculosis.
Guinea-pigs were first experimented on, and one of the prepara¬
tions was then tried on persons in the first stage of pulmonary
phthisis. It is stated that a marked amelioration was produced
in the condition of the patients, whilst successful results were also
obtained in the case of invalids afflicted with lupus. Professor
Koch, in a communication to the Deutsche Medicinische Wochen-
schrift, does not say that the patients who were treated by his new
method were “ cured,” because a sufficient length of time has not
elapsed to enable him to speak confidently on the matter, but he
is reported to be thoroughly satisfied with what has so far been
accomplished. The new tuberculin is being manufactured by the
Hochst Chemical Works and, it is stated, can now be supplied
to hospitals and pharmacies.
Toothache is not Allowed by the Postal Administration of
Geneva, if we may judge from a wonderful document published by
M. Bovet, the Director-General of the Cantonal Post. According
to the Pall Mall Gazette this reads as follows : — “ It often happens
that the postal staff falls ill in consequence of toothache and in¬
flammation ensuing therefrom. Extraction is the only remedy.
But the employes prefer to suffer rather than undergo this opera¬
tion. They abandon their work, and the interests of the post-office
are thereby endangered. This situation cannot last. Notice is
hereby given that the claims of toothache to be considered as an
illness will be no longer admitted by the Administration. Em¬
ployes absenting themselves for this reason will in future be classed
under the schedule ‘ Absences for Pleasure and Preventible Irre¬
gularities,’ and they will have to pay the expenses of their
substitutes. ” Toothache become a pleasure, we may next come to
regard gout, rheumatism, and other painful diseases as luxuries,
and tax their happy possessors accordingly.
The Museums Association meets at Oxford this summer, under
the presidency of Professor E. Ray Lankester, LL.D., F.R.S.
The meeting will begin on the evening of July 7, and continue
till Friday, July 9. The business of the meeting will, as in past
years, consist mainly of the reading and discussion of papers and
the inspection of museums, but owing to the wealth of Oxford in
museums, the latter section of the Association’s work will assume
a more important place than usual. Opportunities for social
intercourse among the Curators attending will also be arranged.
The local secretary of the Association is Mr. W. B. Benham, M.A.,
D.Sc., University Museum, Oxford.
The Exeter Technical College is fortunate in having several
prizes offered by local chemists for competition amongst the
pharmaceutical students attending the classes at that institution.
Four prizes of one guinea each are offered — the first by Mr. Lake,
local secretary for Exeter, and President of the Exeter Chemists’
Association, for pharmacy and materia medica ; the second by Mr. H.
Gadd, J.P., for advanced chemistry; the third by Mr. Rowsell,
Secretary of the local association, for elementary chemistry ; and
the fourth by Mr. G. Stocker, for the best herbarium of plants
collected within ten miles of Exeter during 1897. Mr. Stocker
also contributes a guinea towards the maintenance of the materia
medica collection of the College. Other prizes available to
pharmaceutical students attending the College are the Tucker
prizes, value two guineas and one guinea respectively. Certain
scholarships are also awarded annually.
The Chemical Society held its annual dinner at the Criterion
Restaurant on Wednesday night, when the retiring President,
Mr. A. G. Vernon Harcourt occupied the chair. Among the
guests were Lord Lister, Professor Dewar, the President Elect ;
Mr. Christie, Astronomer Royal ; Dr. Hicks, President of the
Geological Society ; Mr. S. Bid well, President of the Physical Society;
Professor Emerson Reynolds, Mr. Fletcher Moulton, Q.C. ; Dr.
Armstrong, Professor Roberts-Austen, Dr. Messel, Mr. H. Crookes,
Mr. Walter Hills, President of the Pharmaceutical Society ; Dr.
Stevenson, President of the Institute of Chemistry ; and Dr. Ber¬
nard Dyer, President of the Society of Public Analysts. The
toast of the evening, “ Prosperity to the Chemical Society,” was
proposed by Lord Lister, who said he had learned what he
was not previously aware of, that the Chemical Society was
the first ever established for the purpose of considering
chemical subjects only. He had learned also that an
eminent scientist of that time expressed grave doubts whether
chemical subjects could sufficiently occupy the attention of the
Society. But the result showed that the rooms at Burlington
House were becoming quite insufficient for the Society’s pur¬
poses. Of the important work done by the Chemical Society
there was, to an outsider, sufficient evidence in the roll of
illustrious men who had occupied the presidential chair.
The first of these was his master, Professor Graham, and
he did not think that among the many eminent teachers under
whom he worked at University College there was any man who had
inspired him so much as did Professor Graham with admiration and
affection. He had also inspired him with that love of chemistry which
had served him in good stea 1, in his somewhat difficult endeavour to
so apply chemical substances as to exclude mischievous microbes
from wounds, without, at the same time, doing mischief to the
human tissue.
300
PHARMACEUTICAL JOURNAL.
[Apkil 3, 1897
MEETIRGS Of SCIEflTIFIC SOCIETIES
- * -
Chemical Society, Thursday, March 25.— Professor Percy
Frankland delivered his
Pasteur Memorial Lecture
to a large and most appreciative audience. The lecturer paid but
little attention to the great savant’s earlier life, but plunged at
once in medias res, commencing with his brilliant work on the
‘ Tartaric and Racemic Acids,’ and touching in due course upon
his other achievements, such as the manufacture of vinegar, spon¬
taneous generation, pebrine or silkworm disease, and so on to his
last great work on hydrophobia. The Professor was full of anec¬
dote, and he managed to keep his audience in the best of humour
for over two hours. He really said nothing about Pasteur that
was not already well known : the charm in his lecture lay in the
delivery thereof. Lord Lister and Sir Henry Roscoe spoke in
eulogistic terms of Pasteur’s work.
Liinnean Society of London, Thursday, March 18. — Dr.
A. Gunther, F.R.S., President, in the chair. — Mr. G. E. Lodge
was admitted, and Mr. Wm. Martindale was elected a Fellow of the
Society.
Nests of the Chimney Swallow.
Mr. Bernard Arnold, F.L.S. , exhibited three contiguously-
built nests of the chimney swallow, Hirundo rustica, having a
continuous wall of mud as if built by one pair of birds ; but from
the evidence of the observer it appeared that there were two pairs
of birds, and that one pair had made two of the adjacent nests.
The Forms and Functions of Stipules.
The Rt. Hon. Sir John Lubbock, Bart., M.P., read a paper on
“ Stipules, their Forms and Functions.” This embodied observa¬
tions supplementary to those published in previous papers (Linn.
Soc. Journ., Bot., xxviii., 217, and xxx., 463). It was shown that
while the usual function of stipules is to protect leaves in bud, in
some cases they replace them, and in others serve to hold water.
Instances were mentioned in which stipules developed into
spines, and in other cases became glandular. Where stipules
were absent, other arrangements for bud protection were found
to exist. Attention was especially directed to the formation of
the winter buds of certain common shrubs and trees, and some
curious differences were noted even in nearly allied species.
In the wayfaring tree, Viburnum lantana, the author remarked
that the young leaves are uncovered, but are protected by a
growth of hairs ; in the ash and thorn the outer scales of the
bud consist of expanded petioles ; in the willow the outer scales
consist of leaves ; in the poplar of stipules. The buds of the oak
and beech were also described ; and it was shown by the aid of
lantern -slides that in the beech the outer scales of the bud consist
of two pairs of stipules, that the twelfth pair are the first which
have a leaf, and that the subsequent growth is between the leaves,
while the portion of the shoot between the stipules scarcely
elongates at all. As a consequence, the seat of each winter bud is
marked by a ring, and thus a series of successive rings which re¬
main visible for many years indicate each year’s growth.
The Origin of Transfusion Tissue.
Mr. W. C. Wtorsdell read a paper “On the Origin of Trans¬
fusion Tissue in Leaves of Gymnospermous Plants.” It was
explained that “transfusion-tissue” is a special kind of conducting-
tissue found chiefly in the leaves of conifers, in direct connection
with the vascular bundles. “Centripetal” xylem, hitherto only
known to occur in the leaves of cycads among living plants, has
been found, well developed, in the cotyledonary bundles of Ginglco
biloba. In these latter and in the cotyledonary bundles of Cycas
revoluta, a distinct transition was observed between the elements
of the centripetal xylem and those of the transfusion-tissue at the
side of the bundle. In studying the structure of the vascular
bundle in the leaves of conifers generally, a similar transition was
also observed in a few genera between centripetal xylem and
transfusion-tissue. These facts lead to the conclusion that trans¬
fusion-tissue, as universally found in recent coniferous leaves, has
originally sprung from the centripetal xylem of the leaf-bundle of
the ancestors of these plants.
THE WORLD Op PHARMACY.
- + - .
BUSINESS MEETINGS.
Liverpool Pharmaceutical Students’ Society, Thurs¬
day, March 25. — Mr. H. S. Peirson, Vice-President, in the chair. —
A letter was read from the Manchester Chemists’ Assistants’ Asso¬
ciation relative to the special effort being now generally made on
behalf of the
Benevolent Fund,
expressing a wish that Liverpool assistants should join in the good
work and assist in bringing it to a successful issue. The matter
was referred to the Committee, with the suggestion that they
should take such action as would be in accord with that of the
Liverpool Chemists’ Association Committee now working on the
elaboration of a scheme proposed by Mr. J. Smith, the Local
Secretary to the Pharmaceutical Society, with the same object in
view.
Dispensing Difficulty.
A communication from Mr. John AVelsh was then read, in which
he asked for an explanation of a decomposition which had taken
place in a mixture composed as follows : —
Antipyrine . 80 grains.
Sulphate of Quinine . 10 ,,
Dilute Sulphuric Acid . . . 1 drachm.
Syrup of Orange Peel . . 4 drachms.
Cinnamon Water . . to 8 ounces.
Though clear when made, it became opalescent on standing, and
formed a white precipitate on the sides of the bottle after the lapse
of a day. To arrive at the disturbing cause Mr. Welsh made three
experimental mixtures, No. 1 with distilled water, No. 2 with the
antipyrine and cinnamon water only, and No. 3 with the quinine,
dilute acid, and cinnamon water. In none of these was there a pre¬
cipitate, showing that the cinnamon water was the ingredient in the
original mixture which produced the precipitate, composed as was
ascertained of both quinine and antipyrine. When an excess of
dilute sulphuric acid was added to the precipitate to dissolve it, a
pink coloration showed itself, but no solution took place.
Opinions were expressed that it might be the cinnamic ethers of
the small quantity of oil of cinnamon present in the water whichgave
a cinnamate of quinine, or according to Mr. T. S. Wokes, possibly
the aq. cinnamomi had been made by the filtration through
magnesia of water and oil of cinnamon, and consequently it was
not only alkaline but contained partially altered cinnamic ethers.
A paper was then read by Mr. C. Ludlow Tayler on the relation¬
ship existing between
Ethyl Alcohol, Acetaldehyde, and Acetic Acid.
From a consideration of the physico-chemical properties
of the elements composing the bodies under notice, the author
explained the data upon which the generally accepted graphic
formulas were written, and from the variable specific volume of the
oxygen atom, according to the manner in which it is grouped in
the compounds referred to, accounted for, among other apparent
anomalies, the addition products with HCN and the acid sulphites
of the alkali metals, to which acetaldehyde gives rise. The lecture
was well illustrated by means of blackboard drawings of formulae,
etc., and proved to be as interesting from the range of phenomena
and characteristics touched upon ms for the clear and intelligible
manner in which it was delivered.
Edinburgh Chemists’, Assistants,’ and Apprentices’
Association, Friday, March 26. — Mr. George Sinclair in the
chair. — Mr. G. H. C. Rowland gave a very interesting lecture on
First Aid to the Injured,
in which he treated of what should be done in cases of haemorr¬
hage, fractures, dislocations, insensibility, poisoning, drowning,
etc. With the aid of two members of the Association the various
methods of bandaging, splinting, artificial respiration, etc., were
fully demonstrated, and on the motion of the Chairman, a hearty
vote of thanks was awarded to the lecturer. In the discussion which
followed, the great value of ambulance training to a pharmacist was
emphasised, and it was suggested that an ambulance corps might
be formed in connection with the Association.
ABrIl 3, 189?]
PHARMACEUTICAL JOURNAL.
301
Glasgow and West of Scotland Pharmaceutical
Association, Thursday, March 25. — Mr. W. L. Currie, Presi¬
dent, in the chair. — This was a special meeting’ called to consider the
Proposed New Bye-Laws of the Pharmaceutical Society.
The Chairman said some might think the Council had made a
big jump, but with regard to the first part of the proposals, having
reference to raising the standard of the Preliminary examination, he
did not think there would be much difference of opinion. It had
been his opinion of several years that the present examination was
a farce, and no adequate test of the elementary knowledge of any
youth intending to enter the pharmaceutical craft. The examination
proposed was one that should be easily within the reach of a boy leav¬
ing school at theage of fifteen or sixteen years. They were also bringing
themselves into line with all other examining bodies. With regard
to the first part he felt they would be all at one. As to the second
part, which raised the fee from £5 5s. to £10 10s., there might be
some difference of opinion. But they had to remember that the
great majority of those who passed the examinations did not join
the Pharmaceutical Society, and it was only reasonable that they
should contribute a substantial sum to the expenses incurred in
fighting the battles of all registered men, as the Society had to do
in administering the law and keeping the Register. He did not
think a sum of £10 10s. could be regarded as at all excessive.
Some people said that the trade was not worth it in the present
condition of chaos. He quite agreed that they were entitled to
more protection, but if anything was to be done it would be
through the instrumentality of the Pharmaceutical Society. He
was strongly of opinion that a Bill should be promoted for giving
full membership to all registered men. He moved : —
“That the Bye-laws as printed in the Pharmaceutical Journal of March 6,
should receive the hearty support of this Association as they stand.”
— The Secretary read the following letter from Mr. Alex. Laing : —
“ Dear Sir, — Regretting' inability to attend meeting to-morrow night, I
would like to make it known that I am entirely favourable to the new
arrangements of the Pharmaceutical Society relating to examination and
registration. In discarding the “ First" examination, so called, and accept¬
ing certificates of accredited educational bodies only, the Council of the
Society cuts the Gordian knot with a masterly stroke. I am constrained to
approve of the increased fee proposed for the “Minor,” though with reluct¬
ance, for it must be admitted that the majority of “ chemists and druggists ”
on the Register, even those in business, are Pharmaceutical Dead-Heads,
Ltd. , who lack the manliness and stamina to mould or modulate pharmaceutical
polity from within, and whose voices are never heard but in censure and fault¬
finding, a cheap mode of asserting the dignity of their position. From these
the Society has, if not little to fear, little to hope for. It is therefore justified
in making those who will be the pharmacists of the future, who may turn
out dead-heads or not, contribute to the funds of the Society, so as to enable
it to carry out its functions with the vigour and dignity which ought to per¬
tain to such a responsible body. Sound sense and logic are in the case for
the Pharmaceutical Society. Alex. Lainq.”
Mr. Robb seconded the motion. — Mr. Moir said he would have
liked someone else to move an amendment, as he seemed to be always
objecting, but he had opposed this in Edinburgh, and he felt that
he must do so again. He quite recognised that the standard of
the Preliminary examination ought to be raised, and he thought
the present medical preliminary examination was the standard
that should be adopted. But he wanted to know why the proposal
was brought forward just now. The Society had promised them a
Bill embodying a curriculum, and he thought the Bill should have
been brought forward with this proposal as a part of it. If this
proposal was agreed to, it would mean that boys would have to
stay at school till they were sixteen' or seventeen, and the trade
was not worth it at present. Another thing was that
many employers engaged apprentices and let them go on
without caring whether they pass or not. While he
quite agreed that a registration fee should be paid he would
approve a plan for an examination fee of £2 2s. or £3 3s. , and then
let a registration fee be paid on passing. He did not think the
Privy Council would look at the present plan. He quite approved
of the view that the Pharmaceutical Society should be placed in a
position of independence, so as to dispense law and justice
impartially all round, and while he had sympathy with the pro¬
posed bye-laws, he felt bound to move that —
“The time has not yet arrived for the adoption of the bye-laws as proposed.”
Mr. Boyd seconded the amendment. He sympathised very much
with the proposals made in the new bye-laws. He entirely ap¬
proved of the proposed extension of the Preliminary examination,
with the single exception of the modern language, which he
thought they could have done without. As to the increased Minor
fee he did not approve of it, because he thought it was too much
all at once, and they should have gone a little slower. But he never¬
theless had a good deal of sympathy with the proposal, seeing that
so large a proportion of registered chemists do nothing to sustain
the Society. He also strongly favoured the promotion of a Bill
which would make all registered chemists eligible for a seat on the
Councij. He gladly accepted the improvement of the Preliminary,
but thought the time had not come for so great a jump in the
Minor fee, and therefore he seconded the amendment. — Mr.
Russell moved another amendment. He entirely approved
of the proposed extension of the Preliminary examination
and also of the raising of the Minor fee, but he did not see the
reason for a renewal of the £10 10s. fee at the end of a year
after the first failure, and he moved — -
“ That the whole of Bye-law 22, as proposed after and including the words
‘ in cases of ’ be deleted and that, if legal, the fee of £10 10s. shall
constitute life membership of the Society on passing the examination.”
— Mr. Moir said he thought this amendment was incompetent.
They must say either “yes” or “no.” Mr. Boyd said he
thought it was quite competent. — The Chairman said he thought
a new Act would be required to accomplish what the amendment
proposed. He was not sure of its competency but would
let it stand in the meantime. — Mr. Hoseason seconded the
amendment. He heartily agreed with the proposed advance in
the Preliminary examination. If a boy leaving school at fourteen
or fifteen could not pass the examination proposed then he was
sorry for the school. Having been some time engaged in teaching
students, he had had abundant opportunities of seeing that they
were very deficient in arithmetic, and the change would remedy
that. He thought also that it would be an advantage if they
could secure that apprenticeship should not count till the Pre¬
liminary was passed. With regard to the fee, he thought it should
be made a life fee of £10 10.s. or perhaps £12 12s. That might not
be legal, but if not, then he thought they should go in for a new Act. —
Mr. Watson said he agreed generally with the proposal of Mr.
Russell. — The Chairman said he felt that the proposal of Mr.
Russell was outside the scope of the discussion, because it involved
a new Act of Parliament. He therefore ruled that it was not a
competent amendment. — On a vote being taken, eleven voted for
Mr. Moir’s amendment and three for the Chairman’s motion.
Several did not vote. — Mr. Russell said he had been approached
by the students attending the pharmacy schools in Glasgow to ask
if the Association would give them an opportunity of expressing
their opinion. — Mr. Grey suggested that they should send a
memorial to the Council, and this was approved of.
Sheriff Mair’s Decision.
The Chairman said he would again refer to the recent decisions
of Sheriff Mair. He thought they should express the strongest
disapproval of his conduct in calling in question the action of the
Pharmaceutical Society in discharge of its statutory obligation.
He did not think it was proper for any judicial authority to use
such language after the points of law had been so clearly defined
by the highest Courts in England and Scotland. He thought that
something should be done to repudiate the innuendo contained in
the Sheriffs remarks, but he was not sure whether that should be
done in Glasgow or by the Council of the Society. — Mr. Moir said
he quite agreed that Sheriff Mair had gone entirely beyond his sphere
in the remarks he made at Airdrie. At the same time he had
a good deal of sympathy with some part of his remarks, in which
he said that the Act was meant to apply to the owners and not to
the assistants. The Pharmaceutical Society itself held that
opinion till it was defeated in the House of Lords case. He
thought they should not have accepted the suggestion of the
House of Lords, but should have refused to prosecute, and should
have sought fresh legislation. The present interpretation
of the Act was quite contrary to all modern legislation,
such as the law in regard to the sale of whiskey and margarine.
In these cases it was the person whose name was over
the door who was prosecuted. The Pharmacy Act could never
be enforced as at present understood. It was absurd to think so,
for they might have prosecutions in every chemist’s shop. They
should get the Act amended so as to make it apply to the owners,
and he would make a rule that no one should dispense or sell
poisons till he had been three years at the trade. At the same
time, it was perfectly notorious that in Glasgow and the West of
Scotland shops were being carried on with boys and girls in charge
who were quite incompetent. The public were not sufficiently aware
302
PHARMACEUTICAL JOURNAL.
[April 3, 1897.
of this fact and of the danger it involved, and he thought they
should be enlightened. With regard to Sheriff Mair’s remark that
someone was behind the Pharmaceutical Society, he was very
much inclined to reply that someone was behind Sheriff Mair in
his condemnation of the Pharmacy Acts. — Some discussion then
took place as to whether the Association should communicate with
the Council, and the Chairman said he had been in correspondence
with Mr. Bremridge.
Aberdeen Junior Chemists’ Association, Friday, March
26. — Mr. Bremner, President, in the chair.— This was a special
meeting for the consideration of the
Proposed New Bye-Laws
of the Pharmaceutical Society, and the subject received a full
and hearty discussion from the twenty-six members present.
The general opinion was that the scope of the First examination
should be extended as proposed, and passed before commencing
apprenticeship, the present examination being too often crammed
for, and passed by students unfit for the Minor. The raising of
the fee for qualification and registration was supported by Mr. Leslie,
Hon. President, who said that the Society had done a large amount
of good for the trade, and urged all to become associates on qualifying.
He thought an increased fee would have the effect of raising the
standard of the trade and better wages would be got, but considered
it would be unfair to exact a second fee of £10 10s. at the end of a
year in cases of failure. — Suggestions as to charging the extra
£5 5s. on passing or on opening shop, also an annual membership
fee, were made, but were shown to be impracticable, inasmuch as
they would require a new Act of Parliament. — An idea seemed to
be prevalent that the increased fee would mean membership for life
instead of registration merely. Opposition to raising the fee was
chiefly based on the ground that the present income of the Society, if
there were no unnecessary expenditure, should be sufficient for the
administration of the Pharmacy Acts if judiciously applied. —
Ultimately Mr. Watt moved and Mr. Lee seconded
“ That this meeting, while agreeing with the proposed new bye-laws of the
Pharmaceutical Society as regards the First examination, considers that the
proposed increase of the Minor fee is altogether unnecessary and uncalled for.”
A counter motion was made by Mr. Leslie, but was not seconded.
Mr. W atts’ motion was thereupon unanimously supported.
Cricket Arrangements.
Arrangements were then made for forming a cricket club, the
following being elected office-bearers : — President, Mr. Leslie ;
Vice-President, Mr. Bremner; Captain, Mr. Fowlie; Vice-Captain,
Mr. Milne ; Secretary, Mr. Watt ; Treasurer, Mr. Tavendale ;
Committee, Messrs. Fowlie, T. Milne, Watt, Tavendale, Adan,
P. Milne, Philip, and May.
Liverpool Chemists’ Association, Thursday, March 25.—
Mr. A. C. Abraham in the chair. — A sample of “ guaza,” or Indian
hemp, was exhibited by Mr. T. H. Wardleworth, who said it
was interesting from the fact that it was grown in the Ionian
Islands, from whence it was exported to Egypt to be used as
“hashish.” From this it was evident that it possessed the
narcotic properties peculiar to the hemp grown in India, seeming
to disprove the assertion made by many writers that Indian hemp
grown in Europe or in less tropical climates than that of India
resembled ordinary hemp, and was inert or non-narcotic. The
specimen consisted of a thick cake made from the coarsely-
powdered flowering plant by compression, and had all the appear¬
ance and the odour of the Indian drug. After a short discussion,
in which Messrs. Abraham, Conroy, and Cowley took part, the
President then called upon Mr. Herbert E. Davies, M.A., B.Sc.,
to lecture upon the — -
Chemical and Bacteriological Examination of Milk.
The Lecturer dealt with the composition of milk the determi¬
nation of cream-fat and specific gravity, milk sugar, etc. He also
referred in detail to the salts of milk, the presence of preservatives,
ai-d of pathogenic or non-pathogenic germs. An interesting discus¬
sion followed, during which the President remarked that whilst he
believed in fixing a high standard of excellence as regards milk, in
his opinion it would be rather hard to settle upon such a standard
as would cause many men to be fined for selling milk ’which was
pure and unadulterated. In what form was, the asbestos Mr. Davies
employed in the fat estimations ? he should like to ask, for he (Mr.
Abraham) had the honour of being the first one in this country to
advise the use of asbestos cloth for a similar purpose. — Mr. Conroy
had observed evident putridity in some milk he had had recently,
which gave no indication that it was in the least sour. Doubtless
it was one of the preserved kinds Mr. Davies had referred to. He
could not say that formalin was as extensively used in
Liverpool as the borax and boric acid mixture for pre¬
serving milk, and he joined with Mr. Abraham in agree¬
ing that too arbitrary a standard would be an injustice.—
Mr. Hornblower asked if the rise in the specific gravity of milk
after milking was not due to the gradual escape of the dissolved
air it contained. — In reply, Mr. Davies said he held the opinion
that a high standard should be taken in milk analysis. The altera¬
tion of gravity had been proved to be quite independent of the
contained air in the milk. There was a generally received notion
that milk which had been boiled was not so digestible as the fresh,
but this was scarcely borne out in practice, the only change being
a slight coagulation of proteids. He used asbestos cloth, as Mr.
Abraham had advised, in his fat estimations. — A hearty vote of
thanks was given to the lecturer, and the proceedings terminated,
the paper on “Dispensing,” by Mr. Harold Wyatt, Junr., which
should have been read, being postponed to the next meeting, owing
to the late hour.
Brighton Junior Association of Pharmacy, Wednes¬
day, March 24. — This meeting was called for the purpose of
winding up the 1896-7 session and for the election of officers for
the ensuing session and for general business.— The retiring Presi¬
dent (Mr. A. T. Jeeves) spoke of the work of the past session,
saying that he was pleased to be able to say that all their ventures
had resulted in successful issues, and that the sessioh had been parti¬
cularly interesting and instructive as regards papers read and discus¬
sions which had taken place, and that the attendance of members had
been very good indeed. He wished the Association every success
in the future, and complimented the officers and Committee on the
splendid way in which they had worked together in the interests
of the Association. In reference to the Remington’s ‘ Pharmacy ’
offered for competition by Mr. P. M. Short, an evening would be
allotted in the next session’s programme for that.
Election of Officers.
The election of officers was next proceeded with. Mr. Jeeves
was asked to continue as President, but he declined. Mr. C. A.
Blarney (retiring Hon. Sec.) was then proposed as President by
Mr. A. T. Jeeves, and seconded by Mr. A. H. Cupit. This
proposition proved very popular, and Mr. Blarney was vociferously
and unanimously voted to the Presidency. Mr. J. Orr Armour was
next proposed as Vice-President by Mr. C. A. Blarney and seconded
by Mr. W. J. Davies, also carried nem. con. As Treasurer Mr. A. H.
Cupit was proposed by Mr. W. J. Davies and seconded by Mr. A. T.
Jeeves, to be re-elected. Carried unanimously. Secretary, Mr.
W. H. Andrews, proposed by Mr. W. J. Davies and seconded by
Mr. A. T. Jeeves, was unanimously voted to this post. Committee
elected as follows : — Messrs. C. G. Yates, Stanley Kent, Beckwith,
Sant, Feltwell, W. J. Davies, G. B. Savage, and W. Howes.
Benevolent Fund.
The amount collected in the Benevolent Fund contribution box
of the Association during the session amounted to £4 5s.
Edinburgh District Chemists’ Trade Association,
Tuesday, March 30. — Mr. John Bowman, Chairman, in the chair. —
The Secretary (Mr. C. F. Henry) reported that the Committee had
made inquiries as to a circular said to have been sent by a manu¬
facturing firm in London to the medical men of the city, in which
the latter were advised to give their custom to certain depots of
the firm, but as some time had elapsed, and no copy of the
circular was obtainable, the Committee recommended that no action
be taken in the meantime. The report was adopted.
The Picnic.
The Chairman intimated that the Committee recommended that
the Annual picnic should this year be to Selkirk and St. Mary’s
Loch, on Thursday, June 10. It was proposed to take train to Sel¬
kirk, to drive thence up the Ettrick to St. Mary’s Loch, when a
visit would be made to the famous cottage of Tibbie Shiels and to
drive back to Selkirk by the banks of the Yarrow. Dinner would
then be partaken of and the party would return to Edinburgh by
train. This tour was unanimously approved of, and all details
were left to the Committee to carry out. On the motion of Mr.
April 3, 1897.]
PHARMACEUTICAL JOURNAL*
303
McDougall, Mr. Cook, Easter Road, was unanimously elected a
member of the Association, and in view of the Annual Meeting in
May, Messrs. Mackenzie and Wylie were appointed auditors.
SOCIAL MEETINGS.
Chemists’ Assistants’ Association, Thursday, March 25.
— The final dance of the second series of “ Cinderellas” was held
at the Portman Booms, Baker Street, W. , and was a great success.
There were about 170 people present, amongst whom were Mr. and
Mrs. J. C. Umney, Mr. and Mrs. Lucas, Messrs. C. Morley, Hill,
W. Cooper, F. Cooper, T. M. Taylor, Melhuish, Solomon, Strother,
Philp, Pears, Pearson, and H. H. Robins (Hon. Sec.). Dancing
commenced at 7.30 and was continued until midnight. The
programme included sixteen dances, there were also three extras,
opportunity being taken to introduce the “ Washington Post,” and
from the enthusiastic way it was danced, the dance was evidently no
novelty to most of those present. — During the evening Mr. Mobley
(President) announced that in response to numerous requests, and
inasmuch as the series of dances had been supported so well, an
additional but unofficial dance on similar lines would be held in the
same rooms on Tuesday, April 6. Tickets 2s. 6d. each. Any
profit to be devoted to the Benevolent Fund of the Pharmaceutical
Society. — Mr. C. W. Martin again very pleasantly fulfilled the
onerous duties of M.C. to the satisfaction of all.
Midland Chemists’ Assistants’ Association, Wednes¬
day, March 31. — Mr. F. J. Gibson (President of the Midland
Pharmaceutical Association) in the chair. — -The second annual
dinner of the Association was held at the Exchange Restau¬
rant, Birmingham. Amongst those present were Messrs.
C. Thompson, F. H. Alcock, Plaice, Trow, H. S. Short-
house, H. M. Bindloss, H. S. Lawton, F. Casson, Clarke, etc.
After the proposition of the loyal toast, Mr. F. Casson proposed —
“The Pharmaceutical Society.”
He said that there was a great deal said against the Society
which seemed to him altogether unfounded, if they took into
account the work it was doing in putting down the sale of
poisons by unqualified men. Under those circumstances the
Society was worthy of all the support they could possibly
give it. He entirely agreed with the action of the Society in
respect of alteration of the bye-laws, and believed it would be for
the advantage of all. — Mr. Chas. Thompson, in responding,
said that his special mission was to say a few words respecting
The Benevolent Fund
of the Society. The Lord Mayor of Birmingham had issued
some 3000 circulars on behalf of the Jubilee Fund, and he
(the speaker) desired to make an appeal on behalf of the Benevolent
Fund. That Fund distributed something like £2800 annually
amongst distressed chemists and widows, and supported forty-nine
annuitants, who received £50 a year each. It seemed to him
that a fund like that, which was supported by chemists all
through the land, deserved the support of the Birmingham
centre. He did not want them to be behind other
centres, and he suggested that they should form a committee after
the manner of Manchester, and collect subscriptions. Manchester
had done nobly, and he was hoping that Birmingham would not
be behindhand. He had made many notes upon matters he thought
he would speak upon, but the shortness of time prevented
him going into those topics ; at the same time he
appreciated the remarks of Mr. Casson, in reference to what the
Society was doing. They certainly got a lot of kicks, and in the
last week or so one trade paper had gone out of its way to give
them a few kicks rather harder than they were accustomed to.
They were accustomed to be a little hardly dealt with by that paper
but certainly it had surpassed itself during the last few weeks.
Those of them who were able to read between the lines knew that
criticism was not altogether fair. Some eighteen months ago they
held a meeting, and made known their complaints against the
influx of old boots and slippers. The pinch was severe, but it
seemed to him the shoe now pinched in Cannon Street. With
regard to the reference to
“ The Pharmaceutical Journal,”
which was intended to be derogatory, he believed the Journal was
a good property, and would eventually prove a great source of
income to the Society. The Chemist and Druggist had given the
Society a capital advertisement in saying that the members
received 35s. for every guinea subscribed. In conclusion, he
wished the assistants and their Association every success. The
toast of
“The Midland Chemists’ Assistants’ Association”
was proposed by the Chairman. — In responding, Mr. Lawton ex'
pressed his concurrence with the remarks of Mr. Casson respecting
the Pharmaceutical Society, and especially in regard to the altera¬
tion of the bye-laws. — -The speech-making was interspersed with
excellent musical and vocal items.
Plymouth, Devonport, Stonehouse and District
Chemists’ Association, Thursday, March 25. — Several mem¬
bers of this Association met at the Foresters’ Hall to make a
presentation to Mr. E. A. Hodge, delegate of the Junior Section,
who is leaving England for South Africa. It consisted of a silver-
plated, six-chambered revolver, together with an illuminated list
of subscribers. The presentation was made by Mr. Shakerley, sup¬
ported by Messrs. G. Breeze, H. N. Hearder, J. A. Buckley, E.
W. H. Green, and F. H. Ralph, who all expressed regret at his
departure. Mr. Hodge suitably responded for the very handsome
present. At a meeting of the Educational Committee, held on
Friday, March 26, it was decided that the examinations in connec¬
tion with the pharmacy and pharmaceutical Latin classes be held
on April 28 and 29 at the Foresters’ Hall from 6.30 to 8 p.m. Pro¬
fessor H. G. Greenish has kindly offered to set the questions and
examine the answers.
LEGAL REPORT.
PROCEEDINGS UNDER THE FOOD AND DRUGS ACTS.
The Sale of Glycerin and Lime Juice.
At Teddington Police Court, on Monday, the further hearing of
the summons against Thomas Mann, chemist and druggist, of
Hampton Hill, Middlesex, for having sold glycerin and lime juice
not of the nature and substance demanded, was resumed (see ante,
p. 253).
It will be within the recollection of our readers that the adjourn¬
ment was at defendant’s request, in order that a portion of the
sample might be analysed at Somerset House. The certificate of
the Somerset House authorities was read by the Clerk of the
Court, and in substance it stated that the sample contained vege¬
table oil, soap, borax, and glycerin, the last ingredient being
present to the extent of not more than a half or one per cent.
Whether glycerin had been added in a free state or in conjunction
with borax it was not possible to decide.
The Clerk of the Court pointed out that, according to this
certificate, no lime juice was present.
The defendant stated that the preparation, contained essence of
limes. He claimed that he was entitled to have the summons
dismissed under the 25th Section of the Food and Drugs Act upon
the ground that “vexatious and unnecessary summonses and
judgments should be prevented.” At any rate, no costs could
be allowed against him.
Inspector Tyler contended that the certificate of the Somerset
House authorities was incomplete, and further that the purchaser
did not get what he asked for, as half or one per cent, was not a
sufficient substance.
The Bench convicted the defendant and fined him 5s. and costs.
OBITUARY.
Herbert. — On March 19, Henry Seaton Herbert, Pharmaceutical
Chemist, late of Liverpool. Aged 36.
Roper. — On March 23, Richard Roper, Chemist and Druggist,
Dunmow. Aged 61. Mr. Roper had been in business in the town
for many years, and was greatly respected.
Marshall. — On March 25, John Marshall, of 435, Glossop
Road, Sheffield. Aged 35. Mr. Marshall, who was a
native of Bentham, Yorkshire, served his apprenticeship at
Accrington, Cheshire ; he then went to Messrs. Martin and Sons,
chemists, Lewes. In 1882 he became an assistant with Mr.
Newsholme, of Sheffield, where he acted as town traveller until
1888. Mr. Marshall then became a traveller for Messrs. Hearon,
Squire, and Francis, Southwark Street, London, which position
he held up to his death. In Sheffield he was a member of the
local chemists’ association, and in earlier years took an active part
in the formation of the Sheffield School of Pharmacy.
304
PHARMACEUTICAL JOURNAL.
[ApbiL 3, 1897
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Drawings for illustrations should be executed twice the desired size ; clean
sharp lines being drawn with a pen and liquid Chinese ink. Shading by
washes is inadmissible. Photographs can be utilised in certain cases.
Names and Formula: should be written with extra care, all systematic names
of plants and animals being underlined, and capital letters used to commence
generic but not specific names.
Reprints of articles cannot be supplied unless authors communicate with
the Editor before publication.
LETTERS TO THE EDITOR.
The Forthcoming Council Election.
Sir, — The time is just at hand when we shall be invited to elect
fourteen members of Council for the year 1897-8. There can be
no doubt but those members who go out of office in May, and who
have again consented to “accept office if elected,” will be returned,
and I sincerely trust that this will be so, because they have proved
themselves to be worthy of their position. I feel that I may say
this, inasmuch as I am not a candidate, having withdrawn my
name from nomination, thus creating a vacancy to be filled by a
new member, and it appears to me to be very desirable that this
vacancy should be filled by a London man. At present
the number of London members is felt to be too
small, there being only five, upon whom an enormous
amount of work falls, but I am bound to say that the willing
devotion of these five gentlemen is beyond all praise : Such
names as Hills, Carteighe, Martindale, Savory, and Allen inspire
the fullest confidence, but it would be manifestly advantageous in
every way if there were a larger number of members of Council
within easy reach of Bloomsbury Square. In saying this I must
not be understood to disparage or under-value the services of the
provincial members, whose loyalty and self-sacrifice are equal to
those of metropolitan members, but having myself experienced the
disadvantages of living so far from our centre, I venture to sug¬
gest that the proportion of London to country members now
existing, viz., five to sixteen, is much too low for the convenient
discharge of the administrative duties devolving upon the Council
and its various committees. In closing my official career, I beg to
express my sense of the honour which the Society has done me in
electing and re-electing me so many times, and the pleasure I have
had in joining to promote the objects of the Society.
Diss, March 29, 1897. T. P. Gostling.
The Proposed New Bye-Laws.
Sir, — I have taken considerable interest in the controversy that
has been occasioned by the recent proposed alteration of the bye¬
laws, and especially in the recommendation that the qualifying
examination fee should be increased from five to ten guineas. I
am fully of the opinion that the Pharmaceutical Council have
adopted a wise and expedient course when they have arrived at the
time when something must be done to strengthen the hands of the
Society. It appears to me to be one of the chief arguments of
the opposition that it is unreasonable for examinees to contribute
to benefits which they probably will not receive by remaining
assistants and not setting up in business on their own account.
And so it is argued that the prosecutions, etc., instituted
by the Society for the benefit of the trade will not profit
them. But, Mr. Editor, I think it will be obvious to every
thinking mind that whatever affects an employer (especially any¬
thing of an adverse nature) affects the employee, and if the Society
protects my master’s interests in an indirect way it is of benefit to
me, and worthy of my support. Supposing my master’s interests
are not protected, his business may be injured to such an extent
that either he will have to pay his assistant a reduced salary or
dispense with one entirely. This seems to me a view of the matter
that has not been taken into account. It is to be regretted that
the other trade journals should have thought to make capital out
of this question, and I do not think they will benefit by it, but
rather the reverse. They have been a little premature in taking
up the cudgels on behalf of the unqualified man. In
conclusion, I would confess that my writing to you was
prompted by a letter which appeared in last week’s Chemist
and Druggist, and which, if the writer could only reasonably
look at matters he himself would call “ bunkum.” The diatribes
and vituperation aimed at the Society and the Council are so un¬
reasonable that they are absurd to a degree. I am one who, like
my fellow-student, has to provide the money for my examination,
so he may not think I am writing with no thought of the monetary
question. I will not further trespass on your valuable space, but
will express my confidence in the Council and Society and the
pleasure I have in subscribing myself as
March 29, 1897. A Student of the Pharmaceutical Society.
The Proprietary Articles Trade Association.
Sir, — On the assumption that Mr. Johnston writes officially, or
at least that he expresses the views of the P.A.T.A. (or of its
secretary) on substitution, I consider his letter of sufficient im¬
portance to ask you to allow me to refer to it in detail. Whether
or not the value of my criticism is affected by writing anonymously
is a matter of opinion. To reveal my identity would not indicate
to Mr. Johnston whether I wrote from actual knowledge or mere
conceptions more or less erroneous. I simply asked him to explain
a short sentence quoted from his article, and cannot understand
why the tenor of his reply should depend upon the source of the
request. Mr. J ohnston says I am nearly right in the first con¬
struction I put upon his words ; and although he mis-quotes,
the error is probably not material. His “correction” won’t
do : “ Own preparations need not necessarily represent, or be
imitations of, the nostrums, so long as they are as good as, or better
than, the latter for their specific purpose.” Mr. Johnston surely
knows that the professed purpose of the great bulk of advertised
nostrums is not specific. In substituting, I submit that the
“pushed” article must, in its essential features, resemble, re¬
present, or imitate that which it replaces ; otherwise it cannot be
a substitute.
As stated in my former letter, I do not approve of Mr. Johnston’s
classification, and am confident that class (b) has neither the
calibre nor the quantity to entitle it to represent the average
chemist. The vast majority of this class, we are told, are sud-
stitutors. Their maxim is : “ Make as much show of cutting
as you can, and do as little of it as you can.” In other
words : “ Profess what you do not practise.” There is
no other interpretation possible. You announce that you
cut the prices of goods of a certain class, and when those
goods are asked for, you push substitutes on every available occa¬
sion, “ P. AT. A. goods excepted.” To-day, Johnston’s elixir is
persistently pushed in lieu of Blank’s ; to-morrow Blank joins the
P.A.T.A., and the imitation is never again heard of as being as
good as, or better than, the original article ! The ultimate success,
then, of the P.A.T.A. meansthedeathofsubstitution. Mr. Johnston’s
definition of substitution leaves “ the man of gumption and tact ”
no room to operate : “What he thought he would like” implies
hesitancy on the part of the customer, or a desire to solicit the
opinion or advice of the chemist, and though the result is the sale
of “ own preparation,” there is not necessarily any substitution.
“Without attempting to deceive him.” .... Quite “unlike
fraudulent imitation.” It is singular that Mr. Johnston should go
out of his way to deny on behalf of the substitutor any intention to
deceive or defraud when no such thing is as much as suggested in
my letter.
“ Up-to-date chemists and store-assistants appear to be about
equally proficient in the ‘gentle art’ (of substitution) though
probably the latter would bear the palm.” Is the store assistant
the pioneer of British Pharmacy ? Is he a pharmacist at all who
inveigles people into his shop for the purpose of wheedling them
into accepting imitations of the ' articles asked for — not be¬
cause the imitations are as good or better, but because their
sale yields a larger profit ? Mr. Johnston’s closing sentence con¬
tains the pith of the whole letter— ay, and a good deal more.
Allow me to quote it in full : — “ Finally, I shall always maintain
April 3, 1897]
PHARMACEUTICAL JOURNAL.
305
that if an advertiser will not protect the price of his article when
he can now so easily do so, the retailer is justified in ousting that
•article whenever he can, in any way and by any wile (!) consistent
with honour and integrity ( !)” A most remarkable peroration.
I have not come across the word “wile” unless where it im¬
plied “deception,” and in case it might be used in more than
one sense, like the word “herd,” for example. I have consulted
several authorities, including a large “ up-to-date ” dictionary of
•undoubted repute, but the mildest synonym is hopelessly incom¬
patible with honour and integrity. Here are some of them, and
Mr. Johnston can “ tak his pic ” : “A trick or stratagem practised
for insnaring or deceiving ; fraud ; subtlety ; cunning ; deceit ;
^duplicity.” Mr. Johnston says “ herd” is usually applied to oxen
.and swine. Yes, usually, but not always. His letter endorses,
confirms, and ratifies the correctness of its application to persons
as used in my letter. At the risk of intensifying its meaning, I
will close with the original quotation in full : “ Imitatores, servum
pecus.”
March 22, 1S97. Midlothian (86/16).
Sweating the Dispenses.
Sir, — I note “ Anti-Sweater’s ” letter in the Journal of the
"20th, but am by no means satisfied with his reply. If his inten¬
sion really is to improve our position, I do not approve of his
method of going about it, by giving, as an example of “How the
work is done,” an isolated case of gross carelessness and flagrant
-irregularities by a non-qualified man, who has no right to hold the
post of dispenser under the Local Government Board. I did not
Think it at all likely your correspondent would give the name of
The institution referred to, and that is why it was so unfair of him
to quote the case. In the nine years I have been dispenser under
the Poor Law I have received many visits from four different
inspectors, but kept no account of the exact number. There is no
fixed rule, but I have found that, on an average, they visit the
infirmaries about twice a year, and one never knows when they
.are coming or what department they are going to visit. There
was one inspector at our institution last week, and this time he
did not visit me, or I should have shown him “Anti-Sweater’s”
letter and called his attention to the case. As to the advice that
I had better discontinue dispensing, having no other income and
<not wishing to become the inmate of a 'workhouse and dependent
upon the rates, I am not prepared to act upon the suggestion and
-resign my post.
March 22, 1897. Dispenses (86/17).
The Latin of Pharmacy.
Sir, — In an address at Glasgow, partially reported in your last
tissue, Mr. Coull does me the honour of quoting me, with approval,
-as an advocate of the masculinity of rhamnus. What I wrote in
1885 was this : — -
“ Rhanmus is given in most dictionaries as feminine, following the ordinary
rule as to trees, as its Greek progenitor did ; but it is also masculine, in
the same category as Cupressus, Cytisus, Larix, Lotus, and Rubus. Modern
Latin scholars may agree to use the feminine, but they can scarcely make
the language wrong which was written by Latin authors.”
'This, in substance is what I learned in Valpy’s ‘ Latin Grammar,’
half a century since. The Eton grammar (Edwards) and the more
modern Roby make rhamnus masculine. But Mr. Coull gets
greater support still from Lewis and Short’s dictionary, which
;givcs rhamnus as masculine, referring to, but not quoting, Pliny
and Vegetius. Any of your readers interested in so purely an
-academic question, may find an illustration of Lewis and Short’s
contra mundum by consulting the word' angina in almost all the
dictionaries of European origin which (so far as I am aware) give
’the quantity of the second vowel long, i, clenching it by quotation
from the ‘Gradus ad Parnassum.’
Verum angina tibi mistum sale poscit acetum.
(I wish the modern men who talk about fen-assy-tin [phenacetin]
-would scan that line. ) Lewis and Short give angina, supporting
it by an emendation of the same line of Serenus Sammonicus :
Angina vero sibi, etc., etc., and another from Lucilius : Insperato
■abut quam una angina sustul.it hora.
Ryde, March 29. Henry H. Pollard.
Sir, — Mr. Coull’s able and suggestive paper on “ Pharmaceutical
Latin,” in your issue of March 27, is full of practical hints. It
Teems, nevertheless, with debatable points. Among others, the
philological question comes to the front. If Mr. Coull had con¬
sulted the proper authorities he would have seen that the deriva¬
tion he gives of antimonium is far from being the correct one.
Dr. Murray says the word is of unknown origin, but was used as
long ago as the eleventh century. “ Probably, like other terms of
alchemy, a corruption of some Arabic word, re-fashioned so as to
wear a Greek or Latin aspect, perhaps of the Arabic name uthmud
or ithmid, this being possibly an adaptation of the Greek <ntppi,
whence also the Latin stibium. If this conjecture be substantiated,
antimonium and stibium will be transformations of the same word.
Popular etymology has analysed the French antimoine as anti-
moine, against the monks (monk’s bane), and as usual in such
cases, supported the derivation by an idle tale, making the name
originate with the chemist Basil Valentine in the fifteenth century,
more than 400 years late ! ” In his reference to theriaca, Mr. Coull
quotes the authors of ‘ Pharmacographia ’ as confessing ignorance
of the reason why that term came to be applied to molasses. It
was so applied, as Skeat and others think, on account of its
appearance. “ Since triacle was an electuary made with honey
and tinged with saffron, the uncrystallisable syrup that drains
from the sugar refiner’s mould had some resemblance to it, and
inherited its name.” So wrote the late Professor Morley.
The word theriaca has a most interesting derivational history.
The Greek Onpiaxos was an adjective formed from Qppiov, wild beast,
venomous reptile, or viper, this again being the diminutive form of
6jjp, animal (the same root is found to-day in our English word
deer and in the German thier, animal). 6npia.ua <papuana meant
literally wild-beast drugs, i. e. , antidotes to the bites of venomous
animals. The word (papyaxa was afterwards dropped, and Gnpiaxa
stood alone, and was eventually applied to the celebrated antidote
of Andromachus, in which case the name was not only descriptive
of its properties but of its contents, for vipers formed the most
important ingredient of the confection. In Latin the word became
altered to theriaca, and in English to triacle and finally treacle.
It is worth noting that English is the only language which employs
this word (or its equivalent) to describe molasses. The British
Pharmacopoeia, too, is the only one which uses the word theriaca
for that purpose. In all the Continental pharmacopoeias that term
still refers to the electuary of Andromachus or to some modification
thereof. Mr. Coull’s suggestion that we should revert to the old
London and Edinburgh name of sacchari foex is to be heartily
commended.
Brighton, March 30, 1897. C. S. Ashton.
Peach Kernel Oil in Olive Oil.
Sir, — In the oliscussion that followed the reading of my paper
on ‘ ‘ Analysis of Fatty Oils ” before the Liverpool Pharmaceutical
Students’ Society, I was asked to gi\ e a test for the
detection of peach kernel oil in almond oil. In reply
I referred my interrogator to a paper on this subject
in the Pharmaceutical Journal [3j, xvi. , 797, by Mr. T.
Maben, and to which I would also refer your correspondent of
last week. The test stated by him, as given by Maisch, appears
to be a modification of the test given in the German Pharma¬
copoeia, where it is stated that if five measured parts of pure
almond oil are agitated with one measure of a mixture consisting
of two parts of fuming nitric acid and two parts of water, no
brown or reddish colour should appear, and after standing several
hours the fatty layer should form a solid mass, and the aqueous
liquid should be colourless.
Liverpool, March 31, 1897. R. C. Cowley.
The Attfield Testimonial.
Sir, — The Herkomer portrait is finished, and proofs will be
ready for distribution in a few weeks. It is a nearly life-size head,
with a little of the neck, on paper that will be about 17" x 14".
The face faithfully reproduces the impression of vivacious
geniality which those who know Dr. Attfield will recognise as a note¬
worthy characteristic of the popular teacher ; some say there is a
Rembrandt suggestion about it. It is important that all
who desire a copy should communicate (if they have not
already done so) without delay, so that the full number may be
produced at one working, whilst the plate is in the best condition !
Perhaps you will kindly give prominence to this and also to the
fact that up to the present no fewer than 650 names have been
received for the album — including recent and old pupils of Pro¬
fessor Attfield, both at home and abroad, and friends in both
hemispheres, especially amongst the savants of the Continent and
the United States.
39, Tressilian Road, St. John's, S.E. John Moss,
March 31, 1897. Treasurer and Secretary.
306
PHARMACEUTICAL JOURNAL.
[April 3, 1897,
ANSWERS TO QUERIES.
[Queries addressed to the “ Editorial Department, 17, Bloomsbury Square, W.C.,"
will be replied to in the Journal as early as possible after receipt, but the Editor
cannot undertake to reply to them, through the post, nor is it always possible to publish
answers the same week. Questions on different subjects should be written on separate
slips of paper, each of which should bear the sender's name or initials. Readers
requiring working formula for special preparations, and intimating their wants to the
Editor, will be assisted as far as may be practicable. The word "parts," when used in
formula, in variably indicates parts by weight. A nonymous queries will be ignored .]
Name of Plant. — It is a specimen of Adoxa moschatellina.
[Reply to $vtov. — 86/41.]
Exchange Column.— Thanks for the information you send. The
matter will be inquired into. [ Reply to Postal Order. — 87/31.]
Crude Cyanide.— Try May and Baker, Limited, Church Road,
Battersea, S.W. [Reply to J. R. C. — 87/24.]
Potassium Metabisulphite.— It is the acid salt, K2S03-S0.2( = K2
►SO5), sometimes called pyrosulphite. [Reply to H. C. T. G. — 86/12.]
Woolwich Arsenal. — We have no information on the subject.
Address your inquiry to the Superintendent of the Laboratory.
[Reply to A. A. B.— 86/13.]
Cure for Cancer. — We doubt if anyone can give a definite
answer to your question— “ Is there a cure for cancer?” More¬
over, it is entirely a matter for medical men to deal with.
[Reply to Senex. — 86/27.]
Makers of Collapsible Tubes. —Messrs. Betts and Sons,
Wharf Road, City Road, N.E., will make these for you in any
size. We believe these are made from an alloy of zinc and lead. —
[Reply to Hydroquinone. — 85/23.]
Illustrations of Flowering Plants. — Get Shirley Hibberd’s
‘ Field 'Flowers ’ (Groombridge, 3s. 6d.), and subscribe for Cassell’s
‘ Familiar Wild Flowers,’ a re-issue of which is just commencing
publication. [Reply to W. L. B. — 85/34.]
Publisher’s Name. — This was given on page 266e, together with
other particulars regarding the book. The publisher’s address is
London. Note that we cannot undertake to answer queries through
the post. [Reply to M. T. F. — 87/35.,]
Advertising Medium.— Address Pharmaceutical Journal, 5,
Serle Street, Lincoln’s Inn, W.C. It circulates widely in Scotland,
even in the most remote districts, and is undoubtedly the best
medium for your purpose. [Reply to Phos. — 87/26.]
White Heliotrope. — Heliotropine, 90 grains ; extract jasmin,
4 6. ozs. ; oil of ylang-ylang, 5 »l.; terpineol, 15 in. ; otto, 5 m.;
oil of lign-aloe, 15 m. ; glycerin, 2 drachms : essence of tuberose,
3 ozs. ; tincture hibiscus, 2 ozs. ; rectified spirit, to 10 fl. ozs
[Reply to WT. W.— 86/11.]
Preliminary Examination. — Any good school books will do.
Yes! Smith’s,* Principia Latina,’ Parti., is a good elementary
book, whilst Gill’s ‘Oxford and Cambridge English Grammar’
and Hamblin Smith’s * Arithmetic ’ should equally serve your
purpose. [Reply to H. F. — 86/35.]
Lemonade Powder. — Sodium bicarbonate, 1 ounce ; powdered
sugar, 3| ounces ; tartaric acid, 1| ounce ; essence of lemon,
30 minims. Dry the powders thoroughly (a good way is to spread
out on dishes and place in the kitchen oven after the fire is out at
night). Mix the lemon with the sugar, then add the other in¬
gredients. When thoroughly mixed, bottle off into perfectly dry,
hot bottles. [Reply to Piperazine. — 86,28.]
Floral Pomade. — Jasmin pomade, 8 ounces; orange pomade,
8 ounces ; cassie pomade, 4 ounces ; rose pomade, 8 ounces ; pre¬
pared lard, 2 lbs. ; essence of ambrette ( Abelmoschus ), 1 fluid
ounce ; terpineol, 30 minims ; oil of ylang-ylang, 30 minims ; oil
of bergamot, 20 minims. Melt the lard on a water bath, then add
the perfumed pomades, and lastly the oils. Stir until quite cool.
Reply to Piperazine.— 86/28.]
F. L. S.- — You must be recommended by three or more Fellow's
of the Society, pay an entrance fee of six pounds and an annual
subscription of three pounds. Write to the Librarian, Linnean
Society, Burlington House, Piccadilly, W., for a printed form of
recommendation. . [Reply to W. L. B.— 85/34.]
The Sale of Methylated Spirit. — The Act dealing with the
point raised is the 24 and 25 Viet., cap. 91, which imposes a licence
duty in reference to retailing methylated spirit. The following
persons are expressly prohibited by Statute : — A distiller or rec¬
tifier of spirits, a dealer in or retailer of beer, spirits, wines, or
sweets. But the Board does not construe the prohibition very
stringently if it has reason to suppose that undue advantage will
not be taken of the leniency. [Reply to A. H. — 85/15.]
Bye-Laws. — There can be few, if any, who have already been in
the business for some years, and will not be of full age by next
year. There is no reason, therefore, why they should not enter
for the qualifying examination before the proposed new bye-laws
can come into effect. With regard to your second point, it does
not appear that you have read the draft bye-laws. Hence, you
argue under a total misapprehension of the facts. Read proposed
bye-law 22, and after comparing it with existing bye-law 23, you
will find that your supposition is incorrect. [Reply to W. F. B.—
87/28.]
To Perfume Programmes. — Get a tin with a tight-fitting lid—
a biscuit-tin answers admirably, put on the bottom a few pieces
of absorbent cotton, moistened with some such perfume as given
below, cover with a couple of sheets of filter paper ; then pile up
the programmes separately as loosely as possible, and if damp from
the press, so much the better, put on lid and let stand over¬
night in a warm place. Lilac Perfume : — Terpineol, 2 drachms ;
oil of lign-aloe, 20 HI . ; oil of bergamot, 10 14. ; heliotropin,
20 grains ; S.V. Rect., 2 ozs. Mix and sprinkle over the absorbent
cotton. Bouquet Perfume : — 01. bergamot, 1 drachm ; oil sandal,
2 ill. ; oil patchouli, 3 14. ; oil of lavender (best French), 5 til. ;
oil neroli, 10 ill. ; tincture of hibiscus, 2 ounces ; oil of rose gera¬
nium, 5 m . Mix. Violet Perfume : — Ionone, 60 ui . ; oil of star anise,
2 14. ; essential oil of orris, 2 ,rl. ; oil of ylang-ylang, 20 ,Tl. ; ter¬
pineol, 5 nt. ; essence of violet, 2 fl. ozs. [Reply to Minor. — 85/40.]
Colours for Show Bottles. — Dark blue : (1) Sulphate of copper,
1 ounce ; distilled water, 80 ounces ; dissolve, then add solution of
ammonia, 4 ounces ; or q.s., diluted with distilled water, 15 ounces ;
then dilute up to required shade. (2) Take freshly precipitated
iron ferrocyanide, dissolve in oxalic acid and dilute to desired
tint with distilled water. (3) Dissolve sulphate of indigo in
distilled water to produce colour required. Light blue: The
best is merely a solution of sulphate of copper, thus : copper
sulphate, 3 ounces ; water, 29 ounces ; sulphuric acid, 1 ounce.
Mix the acid and water cautiously then dissolve the salt.
Red : Red is a difficult tint to define. What one person calls red
is not the same as that seen by another eye. Bright Red: (1)
Solution of cochineal, 10 parts ; sulphuric acid, 1 part ; water, 89
parts, or sufficient to produce desired tint. (2) Cudbear, 3 drachms ;
water, 1 gallon. Mix and acidulate with sulphuric acid. (3) Con¬
centrated acid infusion of roses, diluted to required depth of colour.
This keeps well, and gives a beautiful tint. [Reply to M. M. — 84/36. ]
INFORMATION WANTED.
“ Australian Febrifuge.” — A correspondent requires a formula
for a preparation to which he applies this name (85/35).
ANONYMOUS COMMUNICATIONS.
A. J. R.- — In accordance with our usual practice, your letter is-
not published because not authenticated with 3'our name and
address.
E. R. B. — “Anonymous queries will be ignored.” This is our
invariable rule, and we must therefore refer you to our instructions
to senders of queries.
COMMUNICATIONS, LETTERS, etc., have been received from
Messrs. Alpers, Ashton, Austen, Beeny, Bennett, Bremridge, Bush, Clarke,
Clement, Cocks, Eberlin, Farr, Fielding, Flitcroft, Ford, Forret, Foster,
Gardner, Gostling, Griffiths, Guyer, Higgs, Hill, Ince, Johnson, Keen, Kemsey-
Boume, Knight, Lane, Lothian, MeFaddle, Marshall, Morgan, Pollard, Reynolds,
Riding, Roberts, Robins, Rowell Russell, Sharp, Sutherland, Warden, White,
Williams, Zimmer,
PHARMACEUTICAL JOURNAL.
ON -THE USE OF STEAM COILS FOR EVAPORATION.
" ^ & T ' c. J. H. WARDEN,
Corrcxporyiihg Member of the Pharmaceutical Society.
following note on the suggested use of flat steam coils
Isj^rfd^ctTar Short distance below the surface of a liquid to be
c ( inceriitra Lpd»'rn'n. v . perhaps, be considered of some interest to
readers of the Journal.
For pharmaceutical purposes jacketed pans are in general use,
but with pans of older construction, in which the jacket is carried
right up to the rim, caking or baking of the extract from adhesion to
the sides, as the volume of the fluid diminishes, is very apt to
occur. Coils fixed to the bottom or wound spirally round the sides
of pans to a certain height are also in use, but from being fixtures
are difficult to clean.
In referring to the use of steam coils, Shears* states that they
should always be placed right at the bottom of the vessel containing
the liquid to be boiled. But I venture to submit that a distinction
ought to be drawn between cases in which it is necessary to heat
a liquid to the boiling point to increase its power of extracting or
dissolving matter, and instances in which the object to be attained
is merely concentration of the liquid by evaporation. In the first
case a steam coil fixed right at the bottom of the pan is no doubt
both theoretically and practically properly placed. On the other
hand, when a liquid has to be concentrated, as in the preparation of
an extract, to apply heat from the bottom of the vessel is not only
unnecessary, and wasteful as regards expenditure of steam, but may
be even highly prejudicial and lead to deterioration in the preparation
of an extract. In heating from the bottom of an evaporating pan,
the whole volume of the liquid is necessarily heated, while evaporation
only occurs from the surface, and in dealing with large volumes
of liquid the continuous exposure to a high temperature of the
whole volume of the liquid during the entire period occupied in
concentration must in many cases be prejudicial.
Of course I am aware that to avoid the effects of a high tempera¬
ture many extracts are preferably prepared in vacuum pans. I
am also aware that proposals have been made to effect evaporation by
heating liquids at the surface by allowing a flame, etc. , to impinge,
but so far as I am aware, no attempt has been made to apply the
heat immediately below the surface of a liquid by means of a
moveable flat steam coil. It would appear feasible, by using
concentric coils of metal tube suspended just below the surface of
a liquid to be concentrated, to obtain all the results now afforded
by the use of expensive jacketed pans, and with economy as
regards expenditure of steam.
The coils might be made of copper steam-pipe, an end being
attached to the steam-cock by means of a Royle’s patent swivel
union, by which the coil could be raised or lowered in the fluid
during concentration. The other end of the coil should be bent and
either provided with a steam- cock to permit of condensed water being
ejected, or with a steam union to allow of another coil being
attached. The steam, after circulating in one coil, would pass into a
second one suspended in another dish and so on, a chain of coils
being formed, and in this way the maximum heating effect of the
steam would be utilised. In using coils in chains, some mechanical
arrangement would have to be made to raise the dishes, as the
fluid level sinks from evaporation, and also to keep the coils always
covered with fluid.
In cases in which copper coils would be unsuitable, the copper
might be tinned or plated with gold, silver, or platinum, or coils
of lead might be used, and there ought not to be any great diffi.
culty in constructing coils of enamelled copper or iron, which
* * Machinery and Apparatus for Manufacturing Chemists.'
Vol. LVHI. (Fourth Series, Yol. IV.). No. 1398.
307
would permit of the most corrosive liquids being concentrated
in large porcelain or stoneware, etc. , pans.
For concentrating a liquid in a pan 3 feet in diameter, a coil of
from 14 to 16 inches in diameter would perhaps be ample, the coils
being wound so as to have an interval of rather less than a quarter
of an inch between the turns of the tube, the coils having much the
appearance of Catherine wheels.
In using a coil such as has been described for evaporation, as
the liquid became concentrated on the surface its density would
be increased, and there would be a tendency for it to sink to the
bottom of the vessel when the liquid was at a comparatively low
temperature, and it would thus be removed from the area of high
temperature. With a dish five or six inches deep it would be
quite possible to boil the liquid at the surface by means of a coil
and, for a time at least, for the fluid at the bottom to indicate
little or no rise in temperature. But after a time the liquid at the
bottom would necessarily become heated, but I should think it
would never reach the temperature of the surface.
Undue heating of the lower stratum of fluid might be obviated
by allowing the dish to stand in cold water up to a certain height ;
or another flat coil through which cold water circulates might be
fixed a few inches below the steam coil, and so cool the con¬
centrated liquid as it sank. Operating in this way, a fluid under
concentration would only be exposed to a high temperature for a
short time, and not continuously as under the existing methods of
heating in jacketed pans or by coils placed at the bottom or round
the sides of evaporating pans.
A SPCRIOUS BALSAM OF TOLU.
BY J. OLDHAM BRAITHWAITE.
Numerous instances of the sophistication of tolu balsam have
been reported on various occasions ; in one sample Mattison " indi¬
cated the presence of storax (Liquidambarorientale) ; later, Nay lor t
reported on a balsam of unknown botanical origin, imported as
tolu balsam ; and recently another sophisticated sample, consisting
apparently of the admixture of some foreign resin, possibly copaiba
resin with genuine tolu, was reported on by myself. +
Tolu has lately attained a high price, and the scanty supply of
genuine balsam has been augmented by heavy arrivals of the
substance under notice.
This has a soft consistence, is very sticky, especially when
chewed, and shows only an occasional crystal when examined by
the microscope, either in its normal condition or after hardening
by exposure op the water bath. It was noticed that during this
heating, and more markedly at a higher temperature, the resinous
portion assumed a much darker red colour than genuine balsam
similarly treated. Extracted with successive quantities of boiling
water it yielded 1T5 per cent, of crystalline acid on cooling. This
acid was fractionally crystallised from boiling water, each fraction
melting sharply at 133° C., and consisting wholly of cinnamic acid.
A sample of genuine balsam similarly extracted with boiling water
gave 4 '2 per cent, of cinnamic acid. On distilling a portion of the
balsam with water, the odour of the distillate was not markedly
differentfrom that of tolu, but contained distinctly more of a fragrant
volatile oil and less cinnamic acid. Treated with bisulphide of
carbon, 61 '4 per cent, was soluble. On evaporating the solvent,
this portion was left as a fragrant brown, transparent, viscid
mass. Its total acid number when saponified with alcoholic
potash was 278.
When extracted with carbon bisulphide genuine tola balsam
* American Journal of Pharmacy, 1S75, 51.
t Pharmaceutical Journal [3], viii., 624.
J Pharmaceutical Journal [4], i., 145.
308
PHARMACEUTICAL JOURNAL.
[ApbilIO, 1897
leaves a perfectly crystalline white residue, consisting almost
entirely of cinnamic acid ; the total acid number of this residue
does not fall below 300. It is evident that the balsam cannot be
considered as the unmixed or partially exhausted product of
Myroxylon toluifera ; experiments have been made with storax and
with a specimen of Liquidambar styraciflua (of which a sample was
kindly placed at my disposal from the Society’s Museum by Mr.
Holmes), and also with coniferous resins, but in no case do the
results obtained by relative treatment with solvents, distillation,
or saponification throw any light on the nature of the substitution.
It seems probable that a balsam agreeing in some respects with
the genuine article but differing markedly in others has been substi¬
tuted in this instance for true balsam of Myroxylon toluifera. Since,
however, its physical and chemical characters are quite distinct
from those given in the British or any other pharmacopoeia, it
should not be employed for pharmaceutical purposes.
My thanks are due to my principals, Messrs. Wright, Layman
and Umney, for whom these experiments have been conducted.
THE IODINE VALUE OF BEESWAX.*
BY R. GLODE GUYER.
In a paper on “Beeswax Analysis” (Ph. J., October 31, 1896),
which I had the honour of reading before this Association, I ex¬
pressed my scepticism as to the published figures referring to the
iodine value. As they did not appear to offer sufficiently reliable
evidence, I decided to defer discussing the subject until I had been
able to further investigate the matter for myself.
In the case of the fixed oils the iodine value is practically the
measure of the proportion of free unsaturated fatty acids. Bees¬
wax, however, does not contain any free unsaturated acids, but is
almost entirely composed of a mixture of free cerotic acid, an
aliphatic acid, a member of the CnH2ll0.2 group, and myricin
palmitate, a neutral compound.
These two main constituents of beeswax are present almost in¬
variably in the proportion of 14 to 86. If beeswax is regarded as
being entirely composed of these two, and estimated as such, the
sum of the percentage composition works out at 102 to 107.
(Hehner. Analyst , 16, 1883), which fact is a direct indication of the
resence of at least another substance. Several compounds have
een alleged to have been isolated by various workers, but their
presence requires confirmation. Amongst them are
Melissic acid.
Myricyl alcohol, probably a decomposition product of myricin.
Ceryl alcohol.
Heptacosane.
Hentriacontane.
These two latter are hydrocarbons of the CnH2ny2 series, and it
is probably due to these or similar hydrocarbons that the iodine is
absorbed. It would be, however, beyond the scope of this paper
to enter any further into the constitutional character of such a
complex substance as beeswax, and I will confine it to the iodine
value and the method employed in obtaining it.
The Iodine Value is the Percentage of Free Iodine absorbed by the
Wax. — The process adopted was strictly that published by Hubl,
with such modifications of a minor character as the case demanded.
In performing the operation certain solutions are necessary.
1st. Iodine solution. This is prepared by dissolving 25 grammes
of iodine in 500 C.c. of alcohol (95 per cent. ) and 30 grammes of
mercuric bichloride in a similar quantity of spirit, and mixing the
two solutions and adjusting to one litre.
2nd. A strictly decinormal volumetric solution of thiosulphate of
sodium.
3rd. Ten per cent, solution of potassium iodide.
It is advisable to work on about 1 gramme to 1 '5 gramme of
wax, accurately weighed and placed in a stoppered bottle of about
f>00 C.c. capacity, with about 50 C.c. of chloroform.
When the wax is completely dissolved by the chloroform, add
20 C.c. of the iodine solution, and set aside in a dark place for
several hours. The length of time necessary for this process is
somewhat a controversial point, but in this particular case the
solution should be allowed to stand for a night, taking precautions
to ensure a normal temperature.
A blank experiment should be conducted simultaneously, working
upon precisely the same quantities of chloroform and iodine solu¬
tion ; by doing so the necessity for standardising the iodine solu¬
tion is obviated, which is a matter of importance, as it is very apt to
vary on keeping, and would therefore have to be checked every time.
* Read before the Chemists’ Assistants’ Association.
The amount of free iodine left in the solution at the end of the
time is estimated by adding 10 C.c. of the potassium iodide solu¬
tion and about 200 G. c. of water, and titrating with the decinormal
thiosulphate solution, using starch water as the indicator.
The difference between the number of cubic centimetre of the
thiosulphate consumed by the two experiments is the measure of
the iodine solution ( 2L) absorbed.
The amount of iodine is then readily calculated from the follow¬
ing formula : —
C.c. iodine solution absorbed x 0*0127 X 100 „ , _ .
- i - = Percentage of iodine.
Weight of wax
The few authorities who cite the iodine value for beeswax are
as previously observed not very concordant in their results, and
moreover, many do not even refer to it.
As I felt that possibly this test might prove of some use if the
range of the value was more restricted, I procured after con¬
siderable trouble several specimens of English wax, the purity and
genuineness of which I knew to be absolute, and I obtained the
following results : —
Iodine Value of English Beeswax.
Dark Yellow, from Barf ord . ,.. 3 samples ... . S'3 8'09 8'12
Light Yellow, from Shillingstone .... .3 samples .... 8'0 7 ’9 7 '9
Dark Red, from Bury St. Edmunds.. . .2 samples ... . S'5 8‘3
Light Yellow, from Horsham . . 2 samples .... 8 '6 8 "4
Dull Brownish Wax, Aberdeen . . 8 '9
It will be observed from these that the average mean is prac¬
tically 8 5. Lewkowitsch quotes in his work 9 '6 as the average.
Minimum . . . 8 '3
Maximum . . . 11 '0
Mean . 9‘6
Wright, on the other hand, gives the average as 10. These,
according to my experience, are too high ; for a wax that agrees in
all other particulars for pure wax will seldom give an iodine value
over 9'0. If the iodine value does exceed that figure, then the
acid number is generally correspondingly high.
From the results I obtained from working on pure virgin English
wax, having the other constants normal, I think the iodine value
should be taken as 8 to 9, and not 9 '6 and 10.
This .test for the purity of beeswax is of distinct analytical
advantage, especially when taken in conjunction with the other
constants. Thus a beeswax adulterated with paraffin wax shows
a marked diminution in the iodine value. A sample of wax having
an iodine value of 8T5 gave the following results when adulterated
with paraffin.
Pure Yellow Wax . 8T5
„ ,, ,j — . +5 per cent. Paraffin = 7-7
10 „ „ = 7-3
20 ,, „ = <P5
On the other hand, tallows, resin, and other similar substances
having a high iodine value necessarily produce a higher iodine
value when added to wax.
The following is an example of a sample of beeswax with added
tallow : —
I. V.
Yellow Wax . Foreign 9’
,, ,, . . + 5 per cent. Tallow 10‘7
10 ,, ,, 12-5
20 „ 16-0
Japanese wax, a fairly frequent adulterant of beeswax, has a low
iodine value of 4. Carnauba wax is slightly higher. These and
one or two other waxes will not materially affect this constant,
but their presence will be noticed by the fluctuation of the other
constants.
The foregoing remarks refer entirely to the yellow beeswax.
Unfortunately, white beeswax does not lend itself to this test.
The body or bodies which are capable of absorbing the iodine are
generally greatly reduced and even obliterated in the bleaching,
especially when bleached by chemical means, so that the iodine
value is of little service, except from a negative standpoint.
If a sample of white wax gives a figure over the mean for that
of yellow wax then it would be at once classed as adulterated, and
on the other hand, one having an iodine value slightly under the
average would not be condemned, or passed as pure.
Therefore, I think that this test has no value for white beeswax
but if taken in conjunction with the other constants is of great
service in determining the purity of yellow beeswax, and that for
analytical purposes, the iodine value for yellow beeswax should
be taken as 8 5, with a maximum of 9 and minimum of 8. In
conclusion I beg to tender my best thanks to Messrs. Hodg-
kinsons, Treacher, and Clarke, in whose laboratories these
experiments were made.
April 10, 1897]
PHARMACEUTICAL JOURNAL.
309
PHARMACEUTICAL SOCIETY
MEETING OF THE COUNCIL.
WEDNESDAY, APRIL 7 , 1807.
Present :
Mr. Walter Hills, President.
Mr. John Harrison, Vice-President.
Messrs. Allen, Atkins, Bateson, Bottle, Carteighe, Corder,
Cross, Gostling, Grose, Hampson, Johnston, Martindale, Park,
Southall, Storrar, Symes, and Young.
The minutes of the previous meeting were read and confirmed.
Calcium Carbide.
The Secretary said he had received from Colonel Majendie a
copy of the circular sent to local authorities with reference
to the keeping of calcium carbide. The circular had been printed
in the Journal. Subsequently it had been found necessary by the
authorities to qualify the term ‘ ‘ pure ” carbide by the word
“commercially,” and a copy of the circular of instructions so
amended had also been sent by Colonel Majendie.
The International Congress at Brussels.
The President said several letters had been received since the
last meeting on the subject of the proposed International Congress
at Brussels in August next. When the invitation was read in
March some doubt was expressed whether this Congress could be
recognised as the legitimate successor of the one held in Chicago,
and it now appeared that, owing to some mistake in the address,
Professor Remington, President of the 7th International Congress,
did not receive the proposal until after a delay of some months, and
the various members of the Standing Committee had expressed their
concurrence in the holding of the Congress at Brussels in August.
It now remained, therefore, for the Council to consider whether
delegates should be appointed. Having regard to the fact that
the Conference in Glasgow would be held at nearly the same time,
he suggested that his colleagues should consider the matter before
the next Council meeting, and make up their minds whether they
would be able to attend, in which case delegates might be appointed.
Election of Members.
Pharmaceutical Chemists.
The following, having passed the Major examination and
tendered their subscriptions for the current year, were elected
‘ ‘ Members ” of the Society : —
Campkin, Francis Sidney ; Cambridge. | James, Henry Palmer ; Kilbum.
Wilson, Harold ; London.
Election op Associates in Business.
The following, having passed the Minor examination, being in
business on their own account, and having tendered their subscrip¬
tions for the current year, were elected “Associates in Business” of
the Society : —
Adamson, Andrew ; Kirkcaldy.
Appleyard, Percy ; London.
Aspinall, Jolm William ; Blackburn.
Beardmore, Alfred E.; Wolverhampton.
Buckley, William ; Lees.
Cumber, Edwin Guille ; Guernsey.
Dale, John Arthur ; Crewe.
Davies, Oliver ; Pontypridd.
Doble, Richard Dennis ; Tavistock.
Duncan, George ; Dufftown.
Ewart, Samuel ; Dalbeattie.
Firth, Marmaduke ; Bradford.
Freeman, Thomas ; Nottingham.
Gammie, John Lawrance ; Macduff.
Grierson, George Arthur ; Lincoln.
Hall, Ernest Edward ; Wolverhampton.
Young, John Arthu
Harries, Benson ; Newport.
Jones, John ; Liverpool.
Macdonald, Alexander ; London.
Marples, Thomas ; Sheffield.
Matz, Max ; Manchester.
Ninnis, Thomas Martin ; London.
Payne, William ; Hitchin.
Ridley, Charles ; Newcastle-on-Tyne.
Round, William Hopkins ; Oldbury.
Savill, William Arthur ; Portsea.
Shepherd, Herbert William ; Burnley.
Simon-, John ; Chester.
Smart, Gordon ; Aboyne.
Sykes, John ; Didsbury.
Tollitt, William ; Worthing.
Young, Fredk. George ; Newport, Mon.
; Newport, Mon.
Election op Associates.
The following, having passed the Minor examination and
tendered their subscriptions for the current year, were elected
“Associates ” of the Society : —
Adams, William Stuart ; Dundee.
Carr, James Augustus ; Sunderland.
Davies, Percy ; Sheffield.
Griffiths, Alfred ; Bristol.
Johnson, Robert Clitherow ; Scawby.
Rosser, William M. ; Abergavenny.
Steven, David ; Oehilltree.
Walmsley, M. ; Kingston-on-Thames.
Election of Students.
The following, having passed the First examination and
tendered their subscriptions for the current year, were elected
“ Students ” of the Society : —
Airey, George Patteson ; Birmingham.
Austin, Henry William ; Nottingham.
Beeston, Arthur Edward ; Norwich.
Brown, Neilson; Loanhead.
Bullock, Edmund Rayner ; Gloucester.
Davies, William Oswal ; Pontypridd.
Dennis, William ; Jarrow.
Drakes, George ; Lincoln.
England, Herbert ; Scarborough.
Eustace, Robert George ; London.
Evans, William ; Carnarvon.
Falck, Charles ; Huddersfield.
Fellows, Benjn. James ; Birmingham.
Gibb, William C. N. ; Winchester.
Hamilton, George A. ; Gatehouse.
Harris, Frank Howard ; Canterbury'.
Hawksworth, John George ; Sheffield.
Huntbach, Herbert ; Preston.
Wormald, J ohn Exle
Huxtable, Zibia Charles ; Bristol.
Jones, Stephen ; London.
Lenfesteyr, Leopold d’Estreville; London,
Lewis, William M. ; Pembroke Dock.
Lindsay, John ; Montrose.
Long, Francis Henry ; Fishponds.
McGlinchy, John Owen ; Reading.
Moore, Francis Howard ; Blackpool.
Nicholson, William ; Glasgow.
Parsons, Harold James ; Exeter.
Paterson, James Jenkins ; Turriff.
Payne, William Hedley ; Haverfordwest,
Rennison, T. J. W.; Kirkby Stephen.
Saunders, Alfred ; Dumbarton.
Trunchion, Herbert Fawdon ; London,
Warren, Edwin James ; Paignton.
Williams, William John ; Burry Port,
Windemer, Oscar ; Pembury.
; Luddenden Foot.
Restorations to Register.
The names of the following persons, who have severally made the
required declarations, and paid a fine of one guinea, were restored
to the Register of Chemists and Druggists : —
Edward Bradley, Dock View Terrace, Ashton-on-Ribble.
Arthur George Crosbie Hunter, High Street, Southend.
Thomas Jos. Pale Levie, 3S, Leazes Park Road, Newcastle-on-Tyne.
Several persons were restored to their former status in the
Society upon payment of the current year’s subscription and a
nominal restoration fee of one shilling.
Nominations for Council.
The Secretary reported that he had received twenty nominations
to fill the fourteen vacant seats on the Council, and that the
following sixteen nominees had declared their willingness to accept
office if elected : —
Allen, Charles Bowen, 20, High Road, Kilbum, N.W.
Atkins, Samuel Ralph, Market Place, Salisbury.
Bottle, Alexander, 4, Godwyne Road, Dover.
Campkin, Algernon Sidney, 11, Rose Crescent, Cambridge.
Carteighe, Michael, 180, New Bond Street, W.
Corder, Octavius, 31, London Street, Norwich.
Grose, Nicholas Male, 8, Temple Street, Swansea.
Hampson, Robert, Norland House, Granville Road, Sevenoaks,
Harrison, John, 33, Bridge Street, Sunderland.
Hyslop, John CahII.i., 39, Church Street, Marylebone, N.W.
Martindale, William, 10, New Cavendish Street, W.
Park, Charles James, 1, Mutley Plain, Plymouth.
Savory, Arthur Ledsam, 143, New Bond Street, W.
Southall, Alfred, 17, Bull Street, Birmingham.
Young, John Rymer, 42, San key Street, Warrington.
Warren, William, 34, Russell Street, Covent Garden, W.C.
The following four nominees had not expressed their willingness
to accept office : — -
Armitage, Nathaniel Newborn, 114, Tong Road, Leeds.
Barrett, Josephus Teague, 30, Regent Street West, Leamington.
Bateman, Thomas Henry, 223, Finchley Road, N.W.
Gostling, Thomas Preston, Linden House, Diss.
3L0
PHARMACEUTICAL JOURNAL.
[April 10. 1897
Nomination of Auditors.
The Secretary reported that he had received the following five
nominations to fill the office of auditor, and that all the nominees
had expressed their willingness to accept office if elected : — •
Butt, Edward Northway, 77, Hamilton Terrace, London, N.W.
Lescher, Frank Harwood, 60, Bartholomew Close, London, E.C.
Stacey, Samuel Lloyd, 22, Great St. Helens, London, E.C.
Umney, Charles, 50, Southwark Street, London, E.C.
Yates, Francis, 101, Southwark Street, London, S.E.
Report of the Government Visitor on the Examinations
in London.
The following report was read.
“ Report on the Examinations held by the London Board of Examiners
of the Pharmaceutical Society of Great Britain during the year
ending March 31, 1897.
“ To the Lords of the Council.
“ My Lords, — I have the honour to report to you for your inf ormation that
during the year ending 31st March, 1897, I have attended twelve examinations of
the London Board of Examiners of the Pharmaceutical Society of Great Britain
during the months of April, July, October, and January.
First or Preliminary Examination.
Numbers.
Candidates examined . 1474
,, who passed... . 680
,, failed . 794
Failed in Latin . 652
„ ,, English . . 428
,, ,, Arithmetic . 719
Percentages.
46-1
53-9
37-5
29-0
48-8
“ These figures do not differ greatly from those of last year. The examination
Is by no means a difficult one, and very elementary.
“The business of a chemist and druggist is one in which an accurate arith¬
metical knowledge is imperative. It is deplorable to find that nearly half the
candidates striving to enter the business are debarred at the outset by their lack
of a knowledge of arithmetic easily acquired at an elementary school. I note,
however, with satisfaction that it is the intention of the Pharmaceutical Society
of Great Britain to raise the standard of the elementary examination, a step
which is most desirable in the interests of the public.
Minor Examination.
Candidates examined .
Numbers.
Percentages.
,, who passed . . .
33-2
,, ,, failed .
Failed in Chemistry .
66-8
26-7
,, ,, Materia Medica .
3-9
„ „ Botany .
111
,, ,, Prescriptions .
4-5
„ ,, Pharmacy and Dispensing . . .
. 186
23-2
, , , , obtaining aggregate number of marks
for a pass . 81
10 T
“ K is gratifying to note that whilst the number of candidates has increased
the proportion of those who passed has also increased. In chemistry, especially,
the improvement is noteworthy, and this is not from any lowering of standard,
but from a great improvement in the practical part of the examination, the
familiarity of candidates with laboratory work being especially manifest.
Major Examination.
Numbers. Percentages.
Candidates examined . 122 _
,, who passed . 60 49 -2
„ ,, failed . 62 50'8
Failed in Chemistry . 20 16'4
,, „ Physics . -. . 11 9-0
,, ,, Materia Medica . 12 9-9
„ „ Botany.. . 10 8'2
,, ,, obtaining aggregate number of
marks for a pass . 25 20'5
“The number of candidates was practically the same as last year (120). The
successes were greater, the increased successes being chiefly in Materia Medica
and Botany.”
General Remarks.
“I have to express my general satisfaction with the manner in which the
Minor or qualifying and Major examinations are conducted, and with the great
and^ steady improvements which have been initiated by the Council of the
Society and carried out by the examiners during the last few years.
“I am, my Lords,
“ Your obedient servant,
March 13, 1897.” “(Signed) Thos. Stevenson.”
The Proposed Bye-Laws.
The President, in proposing that the draft bye-laws be read a
second time, said he should do so pro forma, because he was per¬
fectly aware that, arising out of a discussion which took place at the
General Purposes Committee on the previous night, an amendment
would be proposed with which he was in perfect sympathy. The
amendment, however, did not touch the two main principles
underlying the Bye-laws ; therefore he had no hesitation in asking
the Council formally to read the Bye-laws a second time. Before
he sat down he wished to report what had been done outside
the Council, and the letters and resolutions which had been
received. The first letter was from Mr. A. C. Wootton, Editor of
the Chemist and Druggist, and was as follows : — ■
Letter from the Editor of the ‘ Chemist and Drug gist. ’
42, Cannon Street, London, E.C.
March 16, 1897
The President of the Pharmaceutical Society of Great Britain,
17, Bloomsbury Square, W.C.
Dear Sir, — I have thought it right to lay before the proprietors of the Chemist
and Druggist my view of the action announced at the last meeting of the Counci
of the Pharmaceutical Society in reference to the fees for the qualifying ex¬
amination.
The obvious effect of that policy, if it should be adopted by the Society7 and
approved by the Privy Council, will be to enable the Pharmaceutical Society to
continue an unprofitable, and therefore an unfair, competition in the business in
which we are interested.
You can hardly be surprised to hear that the proprietors of this journal find them¬
selves compelled in self-defence to use whatever opportunities may present them¬
selves to oppose the proposal. I make no secret of the fact that our own considerable
interests influence us in this decision. At the same time, you will, I hope, do us
the justice to believe that we would not move in the matter if we were not
convinced that the policy announced is unjust and unjustifiable.
I am exceedingly sorry to thus find myself in such direct opposition to what
appears to be the unanimous wish of the Council, and I am desired to say that
the proprietors of the Chemist and Druggist share this regret with me.
I am, dear Sir, yours faithfully,
A. C. Wootton,
Editor of The Chemist and Druggist.
Next was a letter Irom the Hon. Sec. of the Western Chemists’
Association, enclosing copy of a resolution passed at a meeting of
that body on March 17. The resolution was as follows : —
“Resolved: That the Western Chemists’ Association (of London) having read
and considered the proposed new bye-laws of the Pharmaceutical Society are
in full accord therewith. They beg to tender their hearty support and co-opera¬
tion in the efforts of the Pharmaceutical Society to advance the education and
interests of chemists generally.”
The following resolution had also been sent up by the Secretary
of the Nottingham and Notts’ Chemists’ Association, which was
passed unanimously at a meeting on the 31st ult. : —
“ That this meeting of the Nottingham and Notts. Chemists’ Association, met
to consider the proposed amended bye-laws of the Pharmaceutical Society,
begs to express its general approval thereof, and expresses its continued con¬
fidence in the President and Council of the Pharmaceutical Societ/.”
The Chemists’ Assistants’ Association (of London), by its Secre¬
tary, had sent a copy of the following resolution : —
‘ That this meeting approves of and strongly supports the action of the
Council of the Pharmaceutical Society in framing the proposed new bye-laws,
being of opinion that they are calculated to serve the best interests of
pharmacy, except that it considers the fee of ten guineas for the Minor
examination should not be paid more than once ; and that the time when
the new bye-law comes into operation should be extended from 1898 to 1900.”
The Cambridge Pharmaceutical Association had passed the
following resolution : — -
* That this meeting of members of the Cambridge Pharmaceutical Association,
and other members of the trade in Cambridge, convened for the purpose of
discussing the proposed new bye-laws of the Pharmaceutical Society, wishes
to express cordial approbation of the efforts of the Pharmaceutical Society to
advance the education and interests of chemists generally.”
They had also just received a resolution passed at a meeting of
the Liverpool Students’ Association : — -
“ That this Association wishes to put on record its appreciation of the bye-laws
proposed by the Pharmaceutical Society as the best means of raising the
status of the pharmacist.”
Finally, he would refer to the passage in Dr. Stevenson’s report
just read, in which he expressed his satisfaction at the intention of
the Society to raise the standard of the elementary examination.
He concluded by formally moving the second reading of the
amended bye-laws. *
The Vice-Presdent had great pleasure in formally seconding
the resolutiou.
Mr. Carteighe moved as an amendment that the last five lines
of Sub-section 22 be deleted. The words proposed to be struck out
had been left in by mistake. There was no intention that, after a
April 10, 1897]
PHARMACEUTICAL JOURNAL.
311
candidate for the Minor examination had paid his fee of ten
guineas, he should have to pay anything more than the plucking
fee at any subsequent time. The tail-end of the bye-law was put in
when the examinations were monthly, and when there was some
reason for it, but it was now altogether out of place. The effect of his
amendment would be that when a candidate had paid his ten
guineas he might present himself at any time thereafter for three
guineas, If the bye-laws were confirmed in the course of the pre¬
sent year, the candidate who presented himself next October and
paid his five guineas would be entitled to come up again for three
guineas without the one year limit being imposed. It was not the
wish of the Council to hurry a man in coming up again when he
had once failed. The effect of the restriction formerly imposed
had a tendency in the past to encourage men to try and get
through within the prescribed period. It also occurred to him
(Mr. Carteighe) that the restriction in Sub-section 24, which had
reference to the amount to be paid by a candidate who gave notice
to be examined but did not appear, should also be removed.
If a candidate gave notice and did not appear, he was practically
fined one guinea, because he had to pay a guinea when he again
gave notice to be examined, and if he sent a medical certificate,
or otherwise satisfied the Council or Board of Examiners that his
absence was unavoidable, he was let off with the fine of a shilling.
This reservation was also restricted to one year, but it would be
better if it were altogether deleted. The propositions now were
that the last five lines of Sub-section 22 should be deleted, and
that a new Sub-section to be numbered 23, and to take the place
of 24 should be added. If the amendments were passed the
wording of the amended Sub-section 22 and Section 23, at present
24, would be as follows : — *
22. Persons who have attended and failed to pass an examination shall not be
entitled to attend on any future occasion unless and until they shall have given
renewed notice of intention to attend an examination, and shall have paid fees
as follows : —
(a ) In respect oj a Major Examination, Two Guineas ;
(b) In respect of a Minor Examination, or a Modified Examination, Three
Guineas ;
(c) In respect of a First Examination, One Guinea.
23. Persons who'have given notice of intention to attend an examination and
have failed duly to attend at the time appointed for the same, shall not be
entitled to attend on a future occasion unless, and until they shall have given
renewed notice of intention to attend an examination, and shall in each case
have paid a fee of One Guinea, — or if the persons shall have proved to the satis¬
faction of the Council or the Board of Examiners (by production of medical
certificates or otherwise) that the said failure was occasioned by unavoidable and
proper causes, — One Shilling.
Mr. Storrar bad much pleasure in seconding the amendment.
Last week they had in Edinburgh an informal meeting of as many
of the past and present examiners and the local executive as they
could get together, when there was absolute unanimity with regard
to the proposed bye-laws, with the exception of one point. They
all agreed that the re-imposition of the ten -guinea fee was illogical
and a mistake, and he had been asked to bring the matter before
the Council. He was glad to find that the people in London were
quite as wise as they were in Edinburgh in seeing that a mistake
had been made. He was quite sure that the amendment proposed
by Mr. Carteighe would be accepted by the Council, but as he was
not present at the last Council meeting he should like to
say a few words on the bye-laws. He was glad to
think that neither in the Council nor in the Society generally
was there likely to be any difference of opinion with regard to the
proposed change in the Preliminary examination. After the report
they had heard read that day from the Government examiner, and
from what they knew themselves, it was evident that some stiffen¬
ing of the Preliminary examination should be made, as it was
necessary to have a more solid educational foundation. With
regard to the increase in the qualifying fee there was no doubt
that there was and would be more difference of opinion. Only five
years ago the fee for the Minor examination was practically doubled,
and it was only natural that their constituents should ask the
Council why it was proposed after such a short interval to again
double the fee. It had been said, and with some truth, that the increase
in the fee would tend to add somewhat to the status of the Society,
and would be to a certain extent beneficial to the candidates them¬
selves in inducing them to come up for examination better prepared.
There was no doubt something in that, but he would put the change
on a much more prosaic foundation ; he would say they increased
it because they required the money. He would not say that their
expenditure was going up by leaps and bounds, but they all knew
that there was a steady increase in the Society’s expenditure year
after year, and it was only natural that it should be so. It was
perfectly well known that this matter had been before the
Council for a long time. He had turned his attention to it as
much perhaps as any member of the Council, and had come
to the conclusion that the bulk of the Society’s expenditure was
absolutely necessary. He had tried honestly and seriously to find
out how the expenditure could be reduced without reducing the
efficiency of the Society, and the only suggestion he could
make was that there should be a reduction in the cost of research
and the cost of the J ournal. This year the expenditure on research
would be considerably reduced, and it was also known that the
increased expenditure on the Journal was only of a temporary
nature, though they must necessarily always look forward to an
apparently adverse balance with regard to the Journal. That
balance was in reality the cost of the Journal to members
and associates of the Society. In his opinion it did not
follow that because they needed money it should come
entirely from the candidates for examination, unless they had a
good case. But he thought they had a good case, because the
great bulk of the expenditure of the Society was for the benefit of
the trade generally quite as much as for the members of the
Society. The investment of the Society’s funds in buildings, both
in London and in Edinburgh, had been called for and rendered
absolutely necessary by the increased demands for examina¬
tions rather than for the Society’s general work. At least
seven-eighths of the total expenditure in Edinburgh was
fairly chargeable to examination purposes. Although the money
that was invested in buildings was practically unremunerative
at present, it was invested in a way not only for the benefit of the
Society, but of the trade generally, because whatever added to the
status of the Society added to the status and position of pharma¬
cists generally. Personally he should have preferred to have an
annual registration fee, instead of a life registration fee. There
were a number of men who were unconnected with the Society,
but who reaped its benefits, and it was a great pity that they could
not be made to pay something. With reference to the suggestion
that the ten-guinea fee would be a severe tax on many of the young
candidates, especially in Scotland, on enquiry from the Assistant
Secretary in Edinburgh, he had ascertained that so many candi¬
dates came up more than once as to make the average fee paid by a
candidate nearly eight pounds.
The President said he would with the concurrence of the Vice-
President at once put the amendment.
The amendment having been at once carried nem. con.,
The President said the amendment now became the substantive
motion, and he should be glad to hear any remarks upon it.
The Vice-President said after Mr. Storrar’s very practical and
interesting remarks, there was very little left to say. The altera¬
tion now agreed to had to a large extent knocked out any opposi¬
tion which could reasonably be raised to the proposal. A great
deal had been said in various quarters which was hardly pertinent
to the question. In his view it was not quite correct to look
on this great reform in the conduct of the examinations as a
question altogether of £s. d., or to say that the examinations cost
so much, that so much was received in fees, and that so much
profit remained. That was only stating half the case. When a
man presented himself and passed the examination they
had not done with him ; they had to put him cn
the Register, to follow his changes of address so as to keep him on
the Register and to protect him in the exercise of his privileges as
a registered man, by purging the Register of all names which
ought not to be there. That work cost money, and they had a
right to look to those who were benefited to provide the necessary
funds. If they had power to insist upon it, no better method than
that of requiring an annual fee could be found, but experience
showed that only about a fourth of those who were put on the
Register joined the Society and contributed an annual subscrip¬
tion to the funds. They were, therefore, driven to act like other
business men. If they were asked to supply goods to a person
whose intention or ability to pay for them was dubious, they
required payment beforehand ; and the same principle should
apply in the case of services to be rendered. He did not think
the proposed alteration would be found to keep many from pre¬
senting themselves for examination, but they would no doubt be
more careful in their preparation when they had ten guineas to
pay. The smaller fee now in force did not prevent men coming up
not prepared to pass, but hoping to squeeze through somehow, but
that was not the class of men they wanted. They wanted men
who had carefully prepared themselves for their work, and who, after
passing the examination and being placed on the Register, would
reflect honour on the Society which had placed them there. He
312
PHARMACEUTICAL journal.
[April 10, 1897
hoped that with the alteration now made the proposal would
receive practically unanimous approval.
Dr. Symes thought most members of the Council must have felt,
on hearing so many resolutions approving of the course proposed,
that it was a little unfortunate that even one letter should have
been received which struck a discordant note, especially as it
appeared to arise from a misconception. That letter suggested,
almost in so many words, that the reason for the change was in
order to obtain more money to subsidise the Journal, because it
was a great tax on the funds and involved an annual loss. Now it
was quite clear to anyone who investigated the matter that such
was not the case ; the apparent balance against the Journal repre¬
sented the cost of supplying it gratuitously to the members, which
worked out at about 8s. per annum, and seeing the average price
for such a journal was 10s., the result was that they supplied the
Journal at the usual price with 20 per cent, discount. It was
obvious to him, therefore, that the ground for opposition failed.
He did not look on the matter as being really a means of
getting more money for the Society to spend, though there
was plenty of work still to be done, and more money
would be of great use. He believed many sympathised
with him in the hope that some day they would see
every registered man a member of the Society, as they ought to be,
but that could not be accomplished without further Parliamentary
powers. It seemed to him that when these new bye-laws came
into force, one objection which might now be urged to a Bill of
that kind would be removed, because it would no longer be a ques¬
tion of money ; a merely nominal fee on membership would alone
be required. He congratulated the President on the support this
suggestion had already received, and trusted it would now be
approved almost unanimously.
Mr. Atkins said he did not regret the opposition which had
been raised, because the only result was to show the per¬
fect bond fides of the proposed change. He was glad
Mr. Carteighe had so frankly moved the amendment,
for it removed the only objection which he had heard raised,
either personally or in correspondence. He shared the view of
Mr. Storrar, that it would be well if they could impose an annual
registration fee, but they had no power to do so. With regard to
the hardship which might be inflicted on the poorer class of
students in Scotland, he would admit there might be some diffi¬
culty, and though it might seem cruel to say so, he did not hesi¬
tate to say that he believed, both in Scotland and the south, that
in future they would have to look for their young men in a class —
he would not say better educated, but financially better placed.
His feeling with regard to the drug trade was that they were
slowly but surely passing through a revolution which would
reduce the number of pharmacists and produce a more highly
educated body of men who would have a restricted area of work.
This would necessitate two changes ; first, the intellectual
standard would be higher than at present for the Preliminary
examination, and financially, a somewhat superior test for admis¬
sion to the business. He did not, however, regard the change with
any mistrust, and he rather hailed the opposition, because the
fuller and freer the discussion the better.
Mr. Southall supported the proposed new bye-laws, saying all
the chemists with whom he had discussed the matter were of opinion
that it was a right step. He hoped that would be found to be
the general opinion throughout the country.
Mr. Johnston said he came up with the intention of opposing
the ten-guinea fee, and did so in Committee on the previous even¬
ing, but the eloquence of one or two of his colleagues had been
too much for him, and he now went entirely with his colleague Mr.
Storrar, and agreed it was the right thing to do.
The President said he was very glad this discussion had taken
place, and he was perhaps more gratified at the few remarks of
Mr. Johnston than at anything else which had been said. He
thanked Mr. Carteighe for having discovered and amended the
mistake which had occurred, but he must say it was neither his
intention nor that of the Committee that the ten-guinea fee should
be charged again and again. On the last occasion the discussion
went largely on the educational question and rightly so, but to-day
the financial question had been mainly dealt with. Some said
they wanted more money, and others said they did not, and there
was some truth on both sides. The more money they had the
better it would be for all men on the Register. A lot of good work
remained to be done, such as the encouragement of local
associations and educational wrork generally throughout the
country, and he ventured to say that, barring- the much-
abused Journal, almost the whole of the wrork done there was
for the benefit of the whole of the registered men. The very
existence of the Museum, Library, and School was an advantage
to every registered man, and the more money they had the better
the work could be done. He must remark, however, that they could
not say yet what would be the effect of this change on the financial
position of the Society. It would certainly mean that even
supposing the number of candidates remained the same as before,
there would be a considerable loss on the Preliminary examination,
because in future they would only receive fees from candidates who
produced certificates, and would not have the unholy gains arising
from the failures of young men who were plucked time after time.
They hoped that in future the Minor candidate would pass the
first time, or at latest the second j they did not want to make money
from repeated failures, and as Mr. Storrar had shown, the average
sum now paid for passing the Minor was probably about £8. They
now proposed that the candidate should pay ten guineas, but they
also hoped that he would pass the first time.
The resolution was then put and carried unanimously that the
amended bye-laws be read a first time.
It was aiso resolved that a special meeting of the Council be
called for April 28, for the purpose of considering and reading of
the bye-laws a second time.
Report oe Finance Committee.
The President, in moving the adoption of the report, said there
was nothing special to call attention to. The payments and
receipts were of the usual character. There had been a goodly
list of subscriptions to the Benevolent Fund during last month as
compared with March of last year. He had also to report with
great satisfaction that they had received a subscription, which they
almost looked for now as an annual thing, of twenty-five guineas
from the Committee of the Chemists’ Ball. That Committee had
also resolved to make a special donation from money they had in
hand towards the J ubilee Fund in May next. The Brighton Junior
Pharmacy Association had sent £4 5s. , collected d uring the past session
of the Association, which was another proof of the interest that the
young men took in the Benevolent Fund. Finally hereferredto thefact
that Mr. Maw had sent one hundred guineas as a donation to the
Fund in the names of his two sons, C. T. Maw and M. T. Maw.
Mr. Maw specially wished this sum to be entered as an ordinary
donation, and not in any way connected with the efforts that were
going to be made in May next.
The report was unanimously adopted.
Report of Benevolent Fund Committee.
The report of this Committee included a recommendation of
grants to the amount of £62 in the following cases : — ■
An Associate in business, (aged 67) from 1870-93 and subscriber during same
period. Has had to give up owing to fading health, and is without means or
friends. (Clapham.)
The widow of a Member (aged 53), who has had several previous grants being
quite helpless from sickness. (Harrogate.)
The widow (aged 43) of an Associate and' subscriber, who was dispenser to a
hospital, and died in October last, leaving three children, only one of whom can
earn anything. (Wandsworth.)
The widow (aged 61) of a registered Chemist and Druggist, who had two grants
before nis death, in 1891, and applicant has had two since. Her bad health pre-
vents her earning anything. (London.)
The widow (aged 62) Of a Member and subscriber, who has had four previous
grants. She is in poor health, but earns what she can. (Bexley.)
A former Associate in business and subscriber (aged 56), suffering from
epilepsy. (Roughton.) 6
One case was deferred for further information, and one was not entertained.
Mr. Bottle (as Chairman of the Committee), after giving some
explanations in Committee on the individual cases, moved that the
recommendations be received and adopted.
This was at once agreed to.
Library, Museum, School, and House Committee.
Library.
The report of the Librarian had been received, including the
following particulars : —
Attendance
Febmar^ . {Evening::::::
Circulation of Books. Total.
February . . 216
Total.
Highest.
, 415
23
. 146
16
Town.
Country.
115
101
Lowest. Average.
10 17
2 7
Carriage paid.
£1 7 s. Vet.
April 10 1897]
PHARMACEUTICAL JOURNAL.
313
Donations to the Library had been announced {Pharm, Journ.,
March 13, p. 238), and the Committee had directed that the
usual letters of thanks be sent to the respective donors.
The Committee had recommended that the second edition of
Brannt’s ‘ Treatise on Fats and Oils ’ be purchased for the Library
in London.
The Librarian had reported that four volumes, missing from the
Library for many years, had been returned anonymously.
Museum.
The Curator’s report had been received, and included the fol¬
lowing particulars : —
Attendance. Total. Highest. Lowest. Average.
rphmimj- /Day . 645 48 14 27
reoruary . /Evening . 56 9 1 2
Several donations had been received {Pharm. Journ., March
13, p. 238), and the Committee had directed that the usual letters
of thanks be sent to the respective donors.
The President, in moving the adoption of the Report, said
there was nothing special to call attention to, and the recommen¬
dations were at once adopted.
Divisional Secretary.
The President proposed that Mr. W. Wilson, of Brixton Road,
be appointed Divisional Secretary for the Brixton Division,
Borough of Lambeth, in place of Mr. Bascombe, who had resigned.
Mr. Wilson was personally known to him, and was, he believed,
eminently qualified to fill the post. The thanks of the Society were
due to Mr. Bascombe for the work he had done on its behalf.
Correspondence.
The President read a letter from an honorary member of the
Society, Rai Badadoor Kanny Lall Dey, of Calcutta,' who had
forwarded a copy of his work on the ‘ Indigenous Drugs of India ’ for
the Library.
A letter was also received from the Privy Council stating that
Dr. G. Balfour Marshall had been appointed visitor to the
examinations of the Society held in Edinburgh in succession
to Sir Douglas Maclagan, who had resigned.
The local secretary at Castle Douglas had written suggesting
that there should be an examination centre for the Preliminary
examination for the South West of Scotland at Dumfries. This
was a matter which would properly engage the attention of the
Council in November next. Dumfries was formerly on the list of
centres, but was deleted in 1878.
A copy of the Pharmaceutical Register and Report of the Pharma
ceu ti cal Council of Western Australia had been received. This
book contained the whole history of the proceedings of that body,
financial and otherwise, and a list of the persons licensed to sell
poisons.
Two pamphlets had been sent by Mr. H. G. Smith, who was
Mr. Maiden’s successor at the Technological Museum at Sydney.
Royal Botanic Society.
The President read a letter from the Secretary of the Royal
Botanic Society, which enclosed a copy of the resolution appointing
him (the President) an honorary member of that Society. He
thought the Council would agree with him that it was very satis¬
factory that he should be appointed a member of that Society,
especially at a time when they were using all their influence to
promote the study of botany.
General Purposes Committee.
The report of the Committee included reports from the Professors
on the Prize examinations, which were all satisfactory, and in
accordance with their reports the Committee recommended the
following awards : —
Botany.
Silver Medal . Steam, Ralph M.
Certificate of Honour . Long, Herbert S. A.
Chemistry and Physics.
Silver Medal . Steam, Ralph M.
Practical Chemistry.
Silver Medal . TTmney, Ernest A.
Certificate of Honour . Stearn, Ralph M.
Silver Medal .
Certificates of Honour
Materia Medica.
Long, Herbert S. A.
Stearn, Ralph M.
Umney, Ernest A.
Upon the recommendation of the Committee, the above awards
were duly made.
The Council then went into Committee to consider the legal
portion of the report of the General Purposes Committee, including
the usual letter from the solicitors as to cases placed in their
hands.
On resuming, the report and recommendations of the Committee
were adopted, and special resolutions were passed authorising the
Registrar to take proceedings against the persons named therein.
PROCEEDINGS UNDER THE PHARMACY ACTS-
PROSECUTIONS IN GLASGOW.
Pharmaceutical Society v. Gilmour.
At the Sheriff Court House, Glasgow, on Wednesday, March 31,
a number of cases instituted by the Registrar under the Pharmacy
Acts, 1852 and 1868, Mr. Bremridge, came before Sheriff Fyfe.
Mr. E. T. Salvesen, advocate, instructed by Messrs. Martin
and Barrie, solicitors, Glasgow, for Mr. P. Morison, S.S.C.,
Edinburgh, appeared for the prosecutor. Mr. Thomson and Mr.
Mackay, solicitors, appeared for Dunlop and Walls respectively.
In the case first taken, Andrew Brown Gilmour, an assistant in
the shop of Dr. Clark, 324, Rutherglen Road, Glasgow, was
charged with two offences for selling laudanum and Powell’s balsam
of aniseed on November 28, 1896, to an agent of the Registrar.
Defender pleaded not guilty, and said he remembered nothing
about the matter.
Mr. Rutherford Hill proved that Gilmour was not registered,
and the analysis of the poisons sold.
Alex. Spence and Joseph Tait proved the purchase of the
poisons.
Dr. Clark appeared as a witness for the defence, and made a
long statement in reply to the Sheriff. He preferred to have un¬
qualified assistants, because they never made mistakes, and
qualified assistants did. He was himself a registered chemist and
druggist. He did not see why he should be stopped selling poisons
by unqualified assistants when his neighbours sold oxalic acid in a
piece of paper twisted and without any label at all upon it. He
would like to know what the Pharmaceutical Society wanted.
They must come to some understanding.
By Mr. Salvesen : He had never told the accused not to sell
laudanum, and it was an ordinary part o'f his duty to sell it.
Castor oil and laudanum were such common things that no one
ever thought anything about it. He told his assistants not to sell
arsenic and other powerful poisons. He was quite sure he was in
the shop when these poisons were sold. He would be in his corn
suiting-room at the back. He thought it was quite enough if he
was on the premises when the poisons were sold. The accused
could not have been alone at the hour these articles were sold. He
would not have found fault with accused if he had refused to sell
laudanum when he was not there.
Mr. Salvesen said the prosecutor had no wish to prose¬
cute assistants who were acting under the instructions
of their employers, who must be regarded as the chief
offenders in conducting their businesses in such a manner.
But they, unfortunately, had no means of getting at the em¬
ployers. In many cases these businesses were carried on without
any name of a person, under such designations as Apothecaries’
Hall and Medical Hall, and it was exceedingly difficult to find out
who the real owners were. They were also frequently medical
practitioners, who could not be proceeded against. It had been
laid down in the English decisions and also in the Tomlinson case
that the actual person who sells must be punished, and that was
the only way in which the Registrar could discharge his
statutory duty, and secure to the public the pro¬
tection which the Statute was intended to . provide.
He thought, however, that the assistant had a valid claim against
his employer for relief for any penalty that might be imposed
upon him, and that he could recover the amount by legal process.
It was perfectly clear that the doctor in this instance, as well as
314
PHARMACEUTICAL JOURNAL.
[April 10, 1897
the accused, was perfectly aware of the numerous prosecutions
that had taken place, and that these offences had not been com¬
mitted ignorantly. He therefore asked that the full penalty
should he imposed.
Sheriff Fyfe said : This is a prosecution of an assistant, and
defender has acknowledged that he is unqualified, and he
seems well aware of the law. It is most unfortunate that
chemists, doctors, and others who keep shops continue this
practice, and shut their eyes to the many warnings they
must have seen in the public prints about prosecu¬
tions under these Acts. The language of this Act is
confused, and the highest authorities have confessed the difficulty
caused by its ambiguity. It would perhaps have been better for
the public interest if it had not been necessary to prosecute these
innocent assistants, and if some means could have been found of
getting at the parties who keep these shops. Of course, at present,
if this were attempted the employer would take refuge in the
defence that his was not the hand that committed the offence, and
then the employ 6 would throw back the responsibility on the
master. The prosecutor would thus be driven from pillar to
post, and the Act would be rendered entirely inoperative.
Though I have some sympathy with the accused, and though
I assume that his master is a qualified chemist, it is my duty to
administer the law as I find it, though it may not be as many
would like it to be. In this case the master and also the accused
seem well aware of the judicial decisions that the person who
actually sells incurs the penalty, even though he be the employe of
a chemist. I have therefore no alternative but to convict him of
this contravention. But he is only an assistant, and I think he is
entitled to some consideration in regard to the penalty, which
should not be so severe in the case of a mere employe as in other
cases. I therefore impose a modified penalty of 10.?. for each
offence, and £2 of expenses.
pense it looked rather like laying a trap. He found the first con¬
travention proved, and imposed a penalty of 10.?., with £1 of
expenses. There seemed a little doubt about the sale of the pills,
and he would give accused the benefit of that doubt.
Pharmaceutical Society v. Walls.
In the fourth case heard, John Walls, an assistant in the shop
of J. and S. Robertson, grocers, 467, Cathcart Road, Govanhill,
Glasgow, was charged with one offence for selling a bottle of Dr. J.
Collis Browne’s Chlorodyne, on November 21, 1896, to an agent
of the Registrar. Mr. Murray, solicitor, appeared for defender
and he pleaded guilty. Mr. Murray said the accused’s employer
was quite unaware that he was committing an offence in selling
this Collis Browne’s Chlorodyne. He thought it was a patent
medicine, and that he was at liberty to sell it. On learning that
it was illegal he had sent his whole stock back to the wholesale
house.
Mr. Salvesen pointed out, both on the outer wrapper and on the
inner label, the bottle was stated to contain chloroform and
morphine, and it was labelled poison. It had been decided in the
case of Piper in the Queen’s Bench Division that this very
preparation came within the Act.
Mr. Murray : That was not Dr. J. Collis Browne’s. The report
only says chlorodyne.
Mr. Salvesen : It was our case, and we know for a fact that it
was Collis Browne’s. Piper’s case followed a Treasury prosecu¬
tion of Davenport, whose name is on the label of this bottle as the
sole maker.
The Sheriff said he thought there was only a technical offence
here, and no intention to infringe the law. The accused seemed
to have mistaken it for a patent medicine. It was also to be
remembered that the offence had been discontinued. He imposed
a penalty of 10s. and £1 of expenses.
Pharmaceutical Society v. Dunlop.
The second case was that of Andrew Dunlop, an assistant in the
shop of Dr. Wilson, 470, Paisley Road, Glasgow, who was charged
with two offences for selling laudanum and Powell’s balsam of
aniseed on November 28, 1896, to an agent of the Registrar. — Mr.
Thomson, solicitor, appeared for accused, who pleaded guilty, and
said he was an experienced dispenser, and had been nine years at
the business.
The Sheriff said that was no excuse. He was quite willing to
assume that accused was as well qualified to dispense as a registered
man, but the pointwas, he did not possess the statutory qualification.
Many medical students were doubtless as well qualified to perform
operations as some medical men. Divinity students were often as
competent as fully-qualified divines, and many law-clerks were as
competent, or more competent, than their qualified masters for
certain pieces of business, but they must all have a proper profes¬
sional certificate. It was the same in this case. He must hold
the accused guilty of the contravention so as to give the public the
security which could alone be secured by the possession of the
statutory qualification. He imposed the same penalties as in the
previous cases — 10s. for each offence and £2 expenses.
Pharmaceutical Society v. Adams.
The next case was against Robert Adams, an assistant in the
shop of Thomas McKee, junior, 386, Cumberland Street, Glasgow,
who was charged with two offences for selling chloroform and mor¬
phine in a mixture dispensed by him, and opium in pills on
November 28, 1896, to an agent of the Registrar.
Defender pleaded not guilty.
Hill, Spence, and Tait proved the charges as in the former case.
Dr. Thomas McKee appeared as a witness for the defence. He
admitted that the prescription produced was copied in his book,
and that the bottle of medicine might have been dispensed, but
he Society’s officer came in hurriedly and as if in great distress,
and the accused had done it to relieve a man in distress. The
pills were not sold in his shop, as they never sold opium pills.
By Mr. Salvesen : The shop was carried on for his son, whose
name was Thomas McKee, jun., but that was to be changed. He
(witness) was also Thomas McKee, jun., as his father was Thomas
McKee, and he was still alive. His son, the accused, and a boy
were the only persons in the shop. None of them were qualified.
The Sheriff said there seemed to be a good deal of looseness in
the way this prescription had been dispensed. The dramatic way
in which the witness seemed to have induced the accused to dis¬
Pharmaceutical Society v. Hunter.
The last case was against David Hunter, an assistant in the shop
of Dr. Taylor, 74, Nelson Street, Glasgow, who was charged with
one offence for selling red oxide of mercury as an ingredient in an
ointment, on November 28, 1896, to an agent of the Registrar.
Defender pleaded not guilty. He did not remember anything
about what happened.
The offence having been proved, the Sheriff imposed a penalty
of 10s. and £1 of expenses.
NOTES AND_F0RMUL£.
( Specially Compiled for the Pharmaceutical Journal. )
Acetone Collodium and Oil of Cade.
Two parts of acetone collodium and 1 part of ol. cadini mixed
are used by Gaucher as a basis for applying medicines. The
mixture is pleasant to use and efficient in the case of psoriasis, as
it does not stain the clothes. —Therap. Monat., xi., 127.
Insecticide for Plant Lice.
Soft soap, 20 ; methylated spirit, 200 ; quassia wood, 6 ; sodium
salicylate, 2J$ ; macerate for several days, filter, and add water,
1000. Apply to the infested plants with a brush ; allow to dry on
and the next day wash off with plenty of water. — U Union Pharm.,
xxxviii. , 72, after Journ. Soc. d’JJort. de Lyons.
Napiithosalicine as an Antiseptic in Laundries.
A patent has been taken out in France for a preparation called
naphthosalicine, which consists of naphthol and salicylic acid
rendered soluble in boiling water by means of borax. The solution
so obtained is not thrown out on rinsing with cold water. For
heavy articles pure alkali may be used in place of borax. — Rev.
Med. Pharm., iv., 77, after Rev. de Chim. Indust.
Carbolic Acid Pastilles.
According to Salzmann, these may be prepared as follows : — •
95 grammes of official crystalline carbolic acid are melted on the
water bath, and 5 grammes stearine soap added. After the solution
of the latter, pour out and stir with the pestle until a doughy crys¬
talline mass results. From this pastilles can easily be made, which
soon set. These pastilles have the advantage that they can be
handled without irritating the hands. — Pharm. Centr., xxxviii., 56.
Apbil 10, 1897]
PHARMACEUTICAL JOURNAL.
315
PROPOSED NEW BYE=LAWS.
Present Bye=Laws.
Stat. 11. All persons who shall tender themselves to the
18^2’ ... Examiners for examination in accordance with the Charter
sec. vm. the Statute, 1852, or the Act, 1868, shall be examined
in their knowledge of the Latin language, in English
Grammar and Composition, and Arithmetic, which Exami¬
nation shall be called the First Examination. Such of the
said persons as shall desire Certificates of competent skill
and qualification to be registered as Chemists and Drug¬
gists under the Act, 1868, shall be examined in or produce
certificates of having previously passed in the First Exami¬
nation, and having been registered as Apprentices or
Students, and shall be examined in the translation and
dispensing of Prescriptions, in Botany, in Materia Medica,
in Pharmaceutical and General Chemistry, Physics and
Posology, and in their knowledge of the law relating to the
sale of Poisons, which examination shall be called the Minor
Examination ; and such of the said persons as shall desire
Certificates of competent skill and qualification to exercise
the business or calling of Pharmaceutical Chemists shall
produce Certificates of having been previously registered
as Chemists and Druggists, and shall be examined in more
extended knowledge of Botany, Materia Medica, Chemistry,
and Physics, or any two of them, which examination shall
be called the Major Examination.
Act 1868, 12. All persons who shall tender themselves to the Ex-
sec. vi. amjners for examination, under the provisions of the Act,
1868, excepting only those specified in the next following
Bye-law, shall be examined in the Minor Examination.
•
Act 1868, 13. All persons entitled to be registered as Chemists and
sec. iv. DrUggists on passing a modified examination, who shall
tender themselves to the Examiners for examination under
the provisions of the Act, 1868, shall pass the Modified
Examination, which the Council of the Pharmaceutical
Society, with the consent of the Privy Council, have
declared to be in their case sufficient evidence of skill and
competency to conduct the business of a chemist and
Druggist, as the same is set out in the Schedule hereto, or
such other modified examination as may in like manner be
declared such sufficient evidence.
Act 1868, 14. The Examiners may grant or refuse to such persons
sec. vi. ag pave tendered themselves for the First Examination, the
Minor Examination, and the Major Examination respectively,
as in their discretion may seem fit, Certificates of com¬
petent skill and knowledge and qualification ; and lists of
such persons shall be delivered by the Examiners to the
Registrar.
Charter, 15. All persons shall, before registration as Apprentices
Act 186^ or Students, pay a fee of Two Guineas, and pass the First
sec. vii. ’Examination, whereupon they shall be registered as
Apprentices or Students.
Stat. 16. All persons desiring registration as Assistants under
1852> ... .the Statute, 1852, or as Chemists and Druggists under the
Act 1868,’ Act, 1868, excepting those named in the next following
sec. vii. Bye-law, shall pay a fee of Five Guineas if previously regis¬
tered as Apprentices or Students, or otherwise a fee of
Seven Guineas, and pass the Minor Examination, where¬
upon they shall be registered accordingly.
Stat. 17. All persons entitled to be registered as Chemists and
1852, Druggists on passing a modified examination, and desiring
Act 1868 so be registered, shall pay a fee of One Guinea and pass
sec. vii. ’the Modified Examination, whereupon they shall be regis¬
tered accordingly.
Proposed Bye=Laws.
11. Prior to July, 1900, persons desiring certificates of competent
skill and qualification to be registered as Chemists and Druggists
under the Act 1868, shall be examined in their knowledge of the
Latin language, in English Grammar and Composition, and
Arithmetic, which Examination shall be called the First Examina¬
tion. Persons intending to present themselves for this Examination
shall give to the Registrar notice in that behalf and pay to him a
fee of Two Guineas not less than 14 days prior to the day which
has been appointed for the holding of the said Examination.
All persons who pass the said Examination shall be registered as
“Apprentices or Students.” After June, 1900, persons desiring
the said certificates of competent skill and qualification under the
Act, 1868, shall deliver to the Registrar on behalf of the Board of
Examiners a certificate of having passed an Examination in English
Grammar and Composition, in the Latin Language, and in one
modern foreign language, and also in Algebra, Arithmetic and
Euclid, conducted by any or either of the examining bodies which
shall have been previously approved for the purpose by such
regulations as are specified by the last preceding Bye Law, and
shall pay a fee of Two Guineas, whereupon, if the Board of
Examiners shall so see fit, they shall be registered as Apprentices
or Students.
12. Persons intending to present themselves to the Examiners for
examination in accordance with the Charter and the Statute, 1852,
or the Act, 1868, and having been registered as Apprentices or Stu¬
dents, shall be examined in thetranslationanddispensingof prescrip¬
tions, in Botany, in Materia Medica, in Pharmaceutical and General
Chemistry, Physics and Posology, and in their knowledge of the
law relating to the sale of poisons, which Examination shall be
called the Minor Examination.
13. Persons desiring certificates of competent skill and quali¬
fication to exercise the business, or calling, of Pharmaceutical
Chemists shall produce to the Registrar evidence of having been
previously registered as Chemists and Druggists, and shall be
examined in more extended knowledge of Botany, Materia Medica,
Chemistry, and Physics, or any two of them, which Examination
shall be called the Major Examination.
14. Persons who shall tender themselves to the Examiners for
Examination, under the provisions of the Act, 1868, excepting only
those specified in the next following Bye Law, shall be examined in
the Minor Examination.
15. Persons entitled to be registered as Chemists and Druggists
on passing a modified Examination, who shall tender themselves
to the Examiners for examination under the provisions of the Act,
1868, shall pass the Modified Examination, which the Council of
the Pharmaceutical Society, with the consent of the Privy Council,
have declared be in their case sufficient evidence of skill and
competency to conduct the business of a Chemist and Druggist,
as the same is set out in the Schedule hereto, or such other
modified Examination as may in like manner be declared such
sufficient evidence.
16. The Examiners may grant or refuse to such persons as have
tendered themselves for the Minor Examination and the Major
Examination respectively, Certificates of competent skill and
knowledge and qualification ; and lists of such persons shall be
delivered by the Examiners to the Registrar.
17. All persons desiring registration as Chemists and Druggists
shall in respect of an examination, to take place prior to the end
of 1898, pay a fee of Five Guineas, and shall in respect of an
examination, to take place after 1898, pay a fee of Ten Guineas,
and shall in either case pass the Minor Examination or the Modified
Examination, whereupon they shall be registered accordingly.
316
PHARMACEUTICAL JOURNAL.
[Apbil 10, 1897
PROPOSED NEW BYE - LAWS — continued.
Present Bye-Laws.
Stat. 18. All persons desiring registration as Pharmaceutical
1852, . Chemists under the Statute, 1852, shall pay a fee of Three
Act 1868 Guineas if previously registered as Chemists and Druggists
sec. vii. by virtue of having passed the Minor Examination, or
otherwise a fee of Ten Guineas and pass the Major Exami¬
nation, whereupon they shall be registered accordingly.
Charter, 19. All persons intending to present themselves for
line 253. examination in the First Examination shall give to the
Registrar notice in writing of their intention in that behalf
not less than fourteen clear days prior to the day which
has been appointed for the holding of the said examination.
Charter, 20. All persons intending to present themselves for
line 253. examination in the Major, the Minor, or the Modified
Examination, shall give to the Registrar notice in writing
of their intention in that behalf on or before the fifteenth
day of the month immediately preceding that in which
the Examination is to take place.
Act 1868, 21. All notices of intention to attend for examination
sec. vii. be p-, attend on the next occasion of the Examination
being held, and all fees in respect of examination and
registration shall be payable on the giving of notice of
intention to attend for examination, and in no case shall
any fee paid in accordance with the Bye-laws be remitted
or returned.
Charter, 22. No person shall be admitted to the Major or the Minor
line 253. Examjnation who shall not have attained the full age of
twenty-one years, nor unless he shall satisfy the Examiners
that for three years he has been registered and employed
as an apprentice or student, or has otherwise for three
years being practically engaged in the translation and
dispensing of prescriptions. Persons who have passed the
Minor Examination at least three months previously may
be admitted to the Minor Examination, and all other
persons desirous of passing the Major Examination may
make application to the Board of Examiners for special
leave in that behalf.
Act 1868, 23. Persons who have attended and failed to pass an
sec. vn. examination shall not be entitled to attend on any future
occasion within an interval of three months therefrom,
nor unless and until they shall have given renewed notice
of intention to attend an examination, and shall have paid
fees as follows
(a) In respect of a Major Examination, Two Guineas ;
(b) In respect of a Minor Examination, Three Guineas ;
(c) In respect of a First Examination, One Guinea ; —
in cases of renewed notices for examinations to be held before
the expiration of one year, computed from the first day of
the month wherein the Examination was held in respect of
which the original fee was paid. In all other cases fees of
amounts corresponding with the fees paid on the original
notice shall be paid.
Act 1868, 24. Persons who have given original or renewed notices of
sec. vn. intenti0n to attend an examination and have failed duly to
attend at the time appointed for the same, shall not be en¬
titled to attend on any future occasion unless and until they
shall have given renewed notice of intention to attend an
examination, and shall have paid fees as follows, viz. : — In
cases of renewed notices for examinations to be held before the
expiration of one year, computed from the first day of the
month wherein the Examination was held in respect whereof
the original fee was paid, — One Guinea, — or if the persons
shall have proved to the satisfaction of the Council or the
Board of Examiners (by production of medical cer¬
tificates or otherwise) that the said failure was
occasioned by unavoidable and proper causes, — One
Shilling, — and in all other cases, fees of amounts
corresponding with the fees paid on the original notice.
Proposed Bye=Laws.
18. Persons desiring registration as Pharmaceutical Chemists
under the Statute, 1852, shall pay a fee of Three Guineas and
pass the Major Examination, whereupon they shall be registered
accordingly.
19. Persons intending to present themselves for examination in
the Major, the Minor, or the Modified Examination, shall give to
the Registrar notice in writing of their intention in that behalf on
or before the fifteenth day of the month immediately preceding
that in which the Examination is to take place.
20. All notices of intention to attend for examination shall be to
attend on the next occasion of the Examination being held, and all
fees in respect of examination and registration shall be payable on
the giving of notice of intention to attend for examination, and in
no case shall any fee paid in accordance with the Bye Laws be
remitted or returned.
21. All persons shall, at the time of giving notice of intention to
present themselves for the Minor Examination satisfy the B&gistrar
that they have attained the full age of twenty-one years, and have
been registered as “Apprentices or Students,” and that they have
for three years been practically engaged in the translation and
dispensing of prescriptions.
22. Persons who have attended and failed to pass an examina¬
tion shall not be entitled to attend on any future occasion unless
and until they shall have given renewed notice of intention to
attend an examination, and shall have paid fees as follows : — -
( a) In respect of a Major Examination, Two Guineas ;
(b) In respect of a Minor Examination, or a Modified Examina¬
tion, Three Guineas ;
(c) In respect of a First Examination, One Guinea.
- o'Hh.,
23. Persons who have given notice of intention to attend an
examination and have failed duly to attend at the time appointed
for the same, shall not be entitled to attend on a future occasion
unless, and until they shall have given renewed notice of intention
to attend an examination, and shall in each case have paid a fee of
One Guinea, — or if the persons shall have proved to the satisfaction
of the Council or the Board of Examiners (by production of medical
certificates or otherwise) that the said failure was occasioned by
unavoidable and proper causes, — One Shilling.
Apbil 10, 1897]
PHARMACEUTICAL JOURNAL.
317
Pharmaceutical Journal.
A Weekly Record of Pharmacy and Allied Sciences.
ESTABLISHED 1841.
Editorial Office: 17, BLOOMSBURY SQUARE, W.C.
Publishing aqd Advertising Office : 5, SERLE STREET, W.C.
LONDON : SATURDAY, APRIL 10, 1897.
THE COUNCIL MEETING.
As arising out of the minutes of the previous Council
meeting, the President mentioned that several letters have
been received on the subject of the proposed International
Congress at Brussels. In regard to the doubt then expressed
whether it could be regarded as the legitimate successor of
the Congress held at Chicago, it has since transpired that
the apparent informality to which reference was made
by Mr. Carteighe arose from the delivery of the letter
to the President of the Seventh International Congress
having been delayed, in consequence of a defective address.
Now that this difficulty has been removed, the Council
will consider the appointment of delegates, and the
President requested his colleagues to inform him whether
they would be able to attend the Brussels Congress in that
capacity and take part in the celebration of the fiftieth anni¬
versary of the Association Generate Pharmaceutique de Bel¬
gique, which will take p'ace in the week following the
meeting of the British Pharmaceutical Conference at Glasgow.
The additions to the Society comprised three Members,
forty-one Associates, and thirty-seven Students.
Out of twenty nominations of candidates for election as
Members of Council four of the nominees have declined to
serve, one of the number being Mr. Gostling, of Diss, who
announced his intention of retiring last week, the others
being Mr. Armitage, of Leeds ; Mr. Barrett, of Leaming¬
ton ; and Mr. Bateman, of Finchley. The new candidates
are Mr. Campkin, of Cambridge ; Mr. Hyslop and Mr.
Warren-, of London. The present auditors have been
nominated for election, and have signified their willingness
to accept office.
The report of Dr. Stevenson to the Pi ivy Council on the
examinations held by the London Board during the year
ending March 31 last, again directed attention to the fact
that nearly half the candidates proposing to take up the
business of a chemist and druggist continue to display a
** deplorable ” lack of knowledge of arithmetic, though the
requirements of the Preliminary examination are very
elementary.
After a formal proposition that the draft of proposed altera¬
tions of the bye-laws should be read a second time, the Presi¬
dent mentioned some letters, received from the secretaries of
several chemists’ associations in different parts of the country,
enclosing resolutions in support of the contemplated change in
the mode of conducting the Preliminary examination and the
increase of the fee to be paid on registration as a chemist and
druggist. These resolutions are in full accord with the
action of the Council, and they show such an appreciation
of it as might be expected. A letter of a very different nature
from the editor of the Chemist and Druggist expressed
disapproval of the action and policy of the Council on
grounds so obviously fallacious and inappropriate as to
require no serious refutation.
Mr. Carteighe then moved, as an amendment, that
certain words should be deleted from Sub-section 22, and
that a new Sub-section, numbered 23, should be added to
take the place of Sub-section 24 of the present bye-laws.
The effect of the first alteration would be to enable a candi¬
date — who had paid the fee for examination and registration
but had failed to pass the examination — to present himself
again at any subsequent time on payment of three guineas.
This will remove the only ground of objection that has been
raised against the increased fee upon grounds of a reasonable
nature, and Mr. Carteighe explained that the necessity for
the amendment arose from an oversight. He pointed out
that the Council had no intention that an unsuccessful
candidate should be hurried to come up again, or
that he should be called upon to pay the full fee over again,
but only the fee for the further examination, and it was by
mistake that the words limiting the time within which the
payment of that fee was to apply were not struck out. The
second alteration related to a restriction in Sub-section 24,
and as that restriction applied to conditions not now existing
it is removed.
Mr. Storrar, in seconding the amendment, said that it
removed the only bar to absolute unanimity in approval of
the new bye-laws among the representatives of Scottish phar¬
macists. The increased fee would probably induce candidates
to come up better prepared ; but he suppoited the increase on
the more prosaic ground that the Society wants money to
meet the naturally increasing and absolutely necessary ex¬
penditure upon work that is of a public nature and is for the
benefit of the trade generally as much as for
that of subscribers to the Society. The great number
of registered chemists unconnected with the Society —
who share in those benefits, but do not contribute to the
expenditure it involves — -should be made to pay something,
and he would like to see an annual registration fep, if it
could be done. The extra fee for qualification might perhaps
be a more severe tax on some candidates than is generally
imagined, especially in Scotland ; but he had ascertained
that, under existing conditions and in consequence of going
up more than once for examination, the average amount paid
by candidates was nearly eight pounds, so that the increased
fee would not after all press so heavily as had been assumed.
The Vice-President remarked that to say the examinations
cost so much and the fees gave a surplus was to state only
half the truth. When a man passed the examination, the
Society had not done with him : year by year he
continued to be a source of expense. Only one-fourth
of the persons becoming entitled to registration joined the
Society, and they should therefore be dealt with on the prin¬
ciple applied in business with questionable people and made to
pay beforehand. Instead of keeping many from entering the
trade, he anticipated that the increased fee would rather pre¬
vent candidates presenting themselves on the chance of
squeezing through. Such he held were not the kind of men
wanted in the ranks of pharmacy.
Dr. Symes spoke of the opposition in one quarter as
being based upon serious misconception, and showed
that the suggestion as to subsidising the Journal being
the reason for wanting more money must appear peculiarly
absurd to anyone who considered the real facts of the case.
318
PHARMACEUTICAL JOURNAL.
[April 10, 1897.
ANNOTATIONS.
The Proposed New Bye-Laws were amended at the meet¬
ing of the Council on Wednesday, by the modification of
one clause and the addition of another. The modification affecting
Bye-law 22, will meet the views of a number of members and
associates of the Society, as well as of many outsiders, who were
inclined to regard with disfavour the possibility of an unsuccessful
candidate having to pay ten guineas on more than one occasion,
or, in other words, to pay the registration fee in addition to the
examination fee more than once. As the proposed bye-law now
stands any person who has attended and failed to pass the qualify¬
ing examination will be entitled to attend on any future occasion
on payment of an additional fee of three guineas, whether before
or after the expiration of twelve months from the date of the exa¬
mination for which the candidate originally entered. This modifi¬
cation, with the corresponding alteration of existing Bye-law 24,
suffices to meet the only reasonable objection that has yet been
raised to the proposed amendments.
Dr. Stevenson’s Report on the examinations is printed in the
present number of the Journal (p. 310), and it will be observed that
he refers with satisfaction to the proposal to raise the standard of
the elementary examination, as being a step which is most
desirable in the interests of the public. As regards the Minor
examination he notes that the proportion qf those who passed
during the year has increased, the result in chemistry being
especially noteworthy, as well as the familiarity of candidates with
laboratory work. The successes at the Major examination were
greater, improvement being shown in materia medica and botany.
Finally, the Government Visitor expresses general satisfaction
with the manner in which the Minor and Major examinations are
conducted, and with the great and steady improvements initiated
by the Council, and carried out by the examiners during the past
few years.
Calcium Carbide not being readily obtainable, if at all, in a
pure state, the Home Office authorities have found it necessary to
modify paragraph (d) in the letter printed on page 234 of the
Journal by inserting the word “commercially.” The restriction
as it stood prevented the use of the carbide entirely, but as it now
reads the use of “ commercially pure carbide ” is permitted.
The Pharmaceutical Society is occasionally spoken of as being
representative of the whole “ trade,” but there is good reason to
believe that the speakers themselves usually regard their language
as figurative only, and many perhaps will be surprised to learn
that the words fairly express the actual condition of affairs. If,
instead of contrasting the fifteen thousand names on the Register
of Chemists and Druggists with the five or six thousand subscribers
to the Society, we consider the proportion of “ active ” members
of the craft — in business on their own account — who sup¬
port the governing body, the results are far from discourag¬
ing. As a matter of fact, there does not appear to be much
room for improvement in this respect, though such is generally
assumed to be the case. For there are probably less than eight
thousand registered chemists in business on their own account,
and those in a position to know are of opinion that at least one-
fourth of those must be left out of consideration in all matters
respecting organisation, etc., which require active participation.
Of the remaining six thousand or less, the Pharmaceutical Society
includes nearly two-thirds, the last report of the Registrar showing
that there are not far short of four thousand registered chemists
in business on their own account who are connected with the
Society. Looking at the question from this point of view, it is
evident that the Society is thoroughly representative of the
“trade,” and alarmists and adverse critics will do well to take
note of the fact.
The Rapid Progress of the P.A.T.A. has drawn attention
to the matter mentioned in the preceding paragraph, it having-
become a matter of interest to investigate how far that body could
be held to represent chemists in business. As stated last week,
the membership of the Association now exceeds two thousand, and
that number includes a working majority of the chemists in busi¬
ness who take an active interest in current affairs, in most of the=
places where the objects of the Association have been advocated.
The representative character of the Association is therefore-
fairly high, and its numbers are continually increasing. Since-
the formation of the Pharmaceutical Society itself, nothing more
remarkable has been witnessed in the shape of organisation
amongst chemists for self-defence than the rapid growth of this
one-year-old Association, which already boasts on its list more than,
half as many chemists in business on their own account as the
Pharmaceutical Society, though the latter has more than fifty years
to its credit as an organised body, and nearly thirty years of full
recognition by the State.
The Glasgow Cases, a brief report of which appeared in last-
week’s Journal, whilst fuller particulars are given in the present
issue(p. 213), are much more encouraging in their results than former
cases heard in the same district. Perhaps the authorities were espe¬
cially fortunate in their choice of an advocate on this occasion, for
Mr. Salvesen seemed thoroughly to have grasped the difficult points,
and his luminous presentation of the state of affairs could hardly
have failed to carry conviction to the mind of any Sheriff. As he
was careful to point out, the Pharmaceutical Society has no special
desire to prosecute assistants who are acting under the instruc¬
tions of employers who are evading the provisions of the Statute ; but,
unfortunately, there are no means of getting at the employers. At
the same time, the Society is required by the Legislature to secure to
the public the protection which the Pharmacy Acts were intended to
provide, and it must therefore proceed, through its Registrar, against
the actual sellers of poisons when they are found to be acting in
contravention of the Statute. The point raised, as to whether,
under such circumstances, the assistant would be regarded as
having a valid claim against his employer for relief in regard to
any penalty imposed upon him, is an exceedingly interesting one,
and if it should prove that the amount of such penalty can be re¬
covered from the employer by legal process, convictions under the
Pharmacy Acts will become much more far-reaching in their
effects than is the case at present.
Sheriff Fyfe’s View has always been that it is unfair to proceed
against assistants, whilst the most guilty parties, those who reap
the profit of the illegal transactions, are allowed to escape. At
last, however, he has been able to regard the matter from a more
comprehensive point of view, and to recognise that shielding the
individuals who alone can be proceeded against, under the
circumstances, tends but to encourage their employers to continue
to act illegally. It is most unfortunate, he observed, that so many
people who keep shops continue to sell poisons illegally, and shut
their eyes to the many warnings they have received. He might
well have employe 1 stronger language in referring to what is
nothing less than systematic evasion and defiance of laws passed
primarily in the public interest. But, whilst the Sheriff expressed
the opinion that it would perhaps have been better for the public
April 10, 1897J
PHARMACEUTICAL JOURNAL.
319
interest if it had not been necessary for the Society to proceed
against comparatively innocent assistants, and if some means
could have been found of getting at the parties who actually own
the shops, he was impelled to acknowledge that if this were
attempted at present the employer would take refuge in the
defence that his was not the hand that committed the offence.
The employ 6 in turn would throw back the responsibility on the
master, and the prosecuting body would thus be driven from
pillar to post, and the Act would be rendered entirely inoperative.
Whilst expressing sympathy with the accused, therefore, Sheriff
Eyfe said it was his duty to administer the law as he found it,
though it might not be as many would like it to be.
The “ Qualification ” of Unregistered Assistants was a point
raised in one of the cases, in which the solicitor who ap¬
peared for accused said the latter was an experienced dispenser,
and had been nine years at the business. But as the Sheriff at
once said, that was no excuse. Even though it be assumed that
an individual is as well qualified to dispense as a registered man,
so far as the sale of poisons is concerned the point is whether or
not he possesses the statutory qualification. Many medical
students, observed the Sheriff, are doubtless as well qualified to
perform operations as some medical men, whilst divinity students
are often as competent as fully- qualified divines, and many law-
clerks are as competent as their qualified masters for certain
pieces of business, if not more competent, but they must all have
a proper professional certificate. It was the same in the present
instance, he said, and the accused must be held guilty of contra¬
vention of the Statute, in order to give the public the security
which could alone be secured by the possession of the statutory
qualification. This brief statement clinches the whole matter and
goes further than many long speeches or articles could go to show
the real nature of the legal qualification as distinct from qualifica¬
tion based on experience. The latter is extremely important, but in
order to meet the views of the Legislatureit must be officially certified.
The French Academy of Sciences has benefited by the muni¬
ficence of Mr. H. Wilde, President of the Manchester Literary and
Philosophical Society, who has written to M. Berthelot announcing
his intention of presenting the sum of £5500 to the Academy, to
be set apart to provide for an annual prize of 4000 francs. This
prize is to be awarded to the person who, in the judgment of the
Academy, best merits it by some discovery in astronomy, physics,
chemistry, mineralogy, geology, or mechanics.
English Post-Office Anomalies are many and varied, but one
to which the attention of the Postmaster-General was directed this
week, by a deputation from the Associated Chambers of Commerce,
is perhaps as absurd as any that have yet been disclosed. Mr. H.
O. Arnold-Forster, M.P., who introduced the deputation, said that
if an English chemist and druggist wishes to post a liquid sample
to a customer in England, India, or the Colonies, he has to send it
to France or Germany to be posted, as the English postal
authorities, while cheerfully accepting and delivering anywhere in
England liquid samples posted abroad, absolutely refuses to allow
an English manufacturer to post a similar sample in his own
country. As a result French and German dealers are permitted to
flood the home markets, India, and our other Colonies with liquid
samples, to the detriment of home producers. Moreover, it is
alleged that when the samples are posted abroad they are, in nine
cases out of ten, sent by the foreign officials vid England and
English mail routes, the English postal officials offering no objec¬
tion. It would appear then that there is no valid objection to con¬
veying liquids, as such. But it is well known that there is a
superabundance of red tape at St. Martin’s-le-Grand, and that is
enough to account for any anomaly.
A Case of Synanthy in Dendrobium Brymerianijm is re¬
corded by Mr. R. Reynolds, of Leeds, who writes to the Gardeners ’
Chronicle respecting a double flower of that plant which has
appeared upon a strong plantof twenty pseudo-bulbs. This plant has
flowered during three previous years, but without anything
abnormal being observed. Dr.' Masters’ ‘ Vegetable Teratology ’
does not mention this species as subject to such deformity, as
the species first came from Burmah four years after the publication
of that work. The flower-stalkis described by Mr. Reynolds as being
strikingly fasciated, with a deep central channel. The structure of
the normal flower would show three sepals, two petals, labellum,
column, and inferior ovary, but in the present case there are five
sepals, of which four occupy the usual position, the fifth being
rather narrow and pendent behind the labellum, whilst there are
three petals, two perfect labella, side by side, and two columns,
Avhich are also side by side. It may be noted that students who
are interested in such matters will find much to interest them in
Dr. Masters’ book.
Nickel Acts upon Ethylene at about 300° C., the main
reaction, according to Sabatier and Senderens (Comptes rendus),
resulting in the formation of methane with liberation of carbon,
although hydrogen is also produced by a secondary reaction. The
amount of hydrogen evolved increases with the temperature of
the nickel. The most rapid reaction was found to be produced on
using nickel obtained by reduction of the oxide by means of
hydrogen, at as low a temperature as possible. Copper, cobalt,
iron, platinum, and palladium did not produce a similar result
when they were used in place of nickel.
Metallic Solutions were treated of by Mr. C. T. Hey cock,
F.R.S., in a recent lecture at the Royal Institution. The
lecturer brought forward some results of work carried on jointly
by Mr. Neville and himself during the past nine years, and
showed a number of experiments which appear to establish an
analogy between the solution of a substance such as sugar in water,
and the solution of metals in each other (see ante, p. 151). Just as the
freezing point of a solution of a salt in water is lower
than that of pure water, so the freezing point of a solution
of a metal, such as thallium, in mercury is lower than that of
pure mercury. In fact, there is no essential difference between
the two phenomena. Van t’Hoff’s theory that a substance in
dilute solution exists within the liquid in a state resembling a gas
was described as affording the best clue to the interpretation of
the results, that contention being supported by means of a table
proving that the results arrived at by experiment agree with
those predicted by the theory. A weak solution of potassium
permanganate was shown to yield at first nothing but pure
colourless ice when frozen, all the salt in solution becoming con¬
centrated in the central unfrozen part. Similarly when gold is
dissolved by metallic sodium, and the solution allowed to solidify
very slowly, though sections cut from the solid alloy appear
perfectly uniform to the eye, exposure of the sections to the X rays
shows that crystalline plates of sodium traverse the mass both horizon¬
tally and vertically, and that the gold has become concentrated be¬
tween the crystalline plates of sodium as the solution solidified.
The analogy between the solidification of an alloy and the solidi¬
fication of an aqueous solution was thus established experimentally.
Sodium, of course, as will be gathered from the above, is trans¬
parent to the X rays, whilst gold is opaque.
320
PHARMACEUTICAL JOURNAL.
[April 10, 1897
CHEMICAL SOCIETY.
The anniversary meeting was held on Wednesday afternoon,
March 31, when Professor Dewar, M.A., LL.D., F.R.S., was elected
President.
The New President.
An ordinary meeting was held on Thursday night, April 1, the
new President taking the chair. There is usually some little en¬
thusiasm shown when a new President takes the chair for the first
time. On this occasion, however, .Professor Dewar’s reception was
decidedly cold. This, without a doubt, was due to his unpopularity
amongst a certain section who opposed his election almost ran-
corously. The gentlemen composing this section of the Society,
however, may be reminded that the doughty Professor is quite at-
home on the subject of low temperatures ; indeed, it is difficult to
imagine for a moment that he was at all dismayed or put out in any
way when he suddenly felt himself in the “cold” atmosphere of
the Chemical Society’s rooms on Thursday night.
The meeting was quite sparsely attended. The late President,
Mr. Vernon Harcourt, looked strangely out of place on the front
bench, and Professr Dewar, in the chair, disclosed the fact that
he was a new hand in many little ways.. Only once did he show
any sign of nervousness, or perhaps it might have been absence of
mind, and that was when he said : “I am afraid we must pass a
vote of thanks,” etc., at which there was loud laughter on certain
benches.
Mr. Cassal had a few words to say on the President’s election
before business was commenced.
The first paper, read by Mr. Stephens, was on
The Hydrolysis of Perthiocyanic Acid,
and 40 per cent. Nitrogen, sulphur, and phosphorus were-
determined by approved methods. The figures for ash show that
there is a loss during cooking. The fat, it appears, is very variable.
Glucose, or carbo-hydrates convertible into glucose, was found to-
be the most troublesome part of the whole work. Proteids were
estimated by the soda-lime combustion method. The last section,
of the paper was devoted to the heat of combustion.
In the discussion which followed the reading of this paper several
gentlemen showed that they had at least seen the fish they were
talking about.— Mr. Groves wished to be informed about the-
determination of fat which, in the salmon, for instance, was dis¬
tributed very unequally over the body, and so with regard to*
mackerel. — Mr. Hehner was not quite sure about the herring,,
which, he said, were sometimes fat and sometimes lean. — Dr.
Kipping spoke in a humorous strain on the question of phosphorus
and brains, and another gentleman, a lecturer on hygiene, con¬
vulsed the meeting by relating the story of a lady who, on being
asked why she fed her daughter so liberally on fish, replied that
she understood that phosphorus was good for making “ matches.” —
A few remarks from Mr. Cassal brought the discussion to a close,
and Miss Williams replied seriatim to the questions that had been
put to her.
Another paper, by E. Aston and J. N. Collie, Ph.D., F.R.S.,
On the Oxidation Products of a-Y-DiMETHYL-a'-CiiLOROPYRiDiNE
was briefly summarised by Mr. Dunstan.
THE WORLD Of PHARMACY.
- 4- - -
NH
NH
by F. D. Chattaway, M.A., and H. P. Stephens, B.A. The authors
in treating potassium thiocyanate with sulphuric acid had separated
thiourea in considerable quantity, and this paper was an inquiry
into the origin of the phenomenon. It appears to be due to the
hydrolysis of perthiocyanic acid, a yellow body which is precipitated
in the first instance. Thiourea is due to secondary decomposition
of this body. Perthiocyanic acid can be hydrolysed in various
ways. With water in a sealed tube it gives rise to the formation
of thiourea, carbon oxysulphide, and sulphur
thus : — H2CsN2S3 + II20 = CS (NH2)2 + COS + S.
On further heating, however, ammonium
thiocyanate is formed. An oily liquid remains
at the bottom of the tube, which the authors
have proved — after a manner — to be hydrogen
disulphide.
A second method of hydrolysing the acid is
ti treat potassium thiocyanate with sulphuric
acid when thiourea is the first product of
decomposition.
Mr. C. E. Groves and the late President put a few questions to
Mr. Stephens, and Professor Dewar asked if the oily liquid referred
to was really hydrogen disulphide, H2S2. — Mr. Stephens, however,
was not quite sure, but he mentioned that they had made samples
of pure hydrogen disulphide, and they found that the oily body
had similar properties.
Although the author of the second paper was present it was
read by Mr. Dunstan. The natural modesty of the author, Miss
K. 5. Williams, probably prevented her going up to the desk to
read her paper on
The Composition of Cooked Fish.
S CS
Perthiocyanic acid.
Mr. Dunstan skimmed over the voluminous notes, picking out
the salient points of Miss Williams’ paper. It is an investi¬
gation taken up with the idea of discovering what changes take
place in fish which have undergone the process of cooking. It is
one of those papers whose chief value lies in a comparison of the
tables of figures obtained. About twenty or thirty different kinds
of fish had been used for the work, and considering the number of
determinations which had been made and all of them repeated
the third time, the work Miss Williams has accomplished must
have been enormous. Mr. Dunstan drew laughter from the
audience as he read the list of fish that had been used. It
included salmon, sardines, haddock, herring, oysters, and so on.
The chemical part of the paper dealt with the determination of
the water, the samples being kept on the steam bath for twelve to
twenty-four hours. Carbon and hydrogen were next determined,
the figures for these being respectively something like 8 per cent.
BUSINESS MEETINGS.
Proprietary Articles Trade Association, Wednesday,
March 31. — Previous to a meeting of the Council of the P.A.T.A.,
a meeting of the retail section of the Council was held at the
office of the Association. All the members were present. Mr.
W. R. Barnes was selected as Chairman of this branch of the
Council for the ensuing year, and it was decided, the Secretary
stated, that the Executive Committee would recommend to
the Council that a retail member of the Council should
be appointed President for the present year, as they had
already had a member of the manufacturer’s section as well as of
the wholesale section holding that office in the past. The meeting
decided to nominate Mr. W. Jones, of Birmingham, for President,
and Mr. Herbert W. Seely as the retailers’ Vice-President. It
was also decided to nominate Messrs. A. Cooper and W. R. Barnes,
the London members of the section, to act as the retailers’ repre¬
sentatives upon the Executive Committee of the Association. The
resolution was unanimously passed requesting the secretary to
write to the various local associations who were at present
supporting the P. A. T. A. , requesting them to thoroughly organise
the work of the P.A.T.A. in their respective districts. That where
possible, a special committee of the Association be appointed,
and that the whole trade in the districts should be thoroughly
canvassed. The meeting also unanimously decided that the
Secretary should write to all candidates at the next election of
the Pharmaceutical Council requesting their views upon the
P.A.T.A. movement for publication to the members of the Asso¬
ciation, and that the members of the P.A.T.A. be urged to
support only those candidates whose replies were considered
satisfactory.
MEETING OF THE COUNCIL.
At a meeting of the Council of the Association, held at
Anderton’s Hotel, Mr. G. R. Barclay took the chair, and the
business of electing a president for the ensuing year was at once
proceeded with, Mr. W. Jones, Chairman of the Chemists’ Trade
Committee, on the motion of Mr. H. J. Hall, being elected to
the office. — The Secretary read the report of the Executive Com¬
mittee, which contained several recommendations re the constitu¬
tion of the Committee, and stated that the Grocers’ Federa¬
tion before taking any action in conjunction with the
P.A.T.A. desired to have the legal position of the move¬
ment more positively and sufficiently ascertained. The
Committee, for the satisfaction of the Grocers’ Federation, had
decided to obtain the opinion of Sir Edward Clarke. — Mr. Wokes
Afeil 10, 18971
PHARMACEUTICAL JOURNAL,
321
moved the adoption of the report, and Mr. John Williams (Man¬
chester) moved a resolution to the effect that the Executive
Committee be instructed to take the earliest possible steps towards
forming a separate list of grocery articles. This was seconded by
Mr. G. R. Barclay and carried unanimously.— Messrs. J. Cocks
and S. N. Pickard wished to know what steps were to be taken in
certain special cases of cutting which had come under their notice.
Satisfactory answers were given by the Secretary. — The report
and financial statement to be submitted to the annual meeting
being discussed and adopted, the meeting then concluded.
FIRST ANNUAL MEETING.
Subsequently the first annual meeting of the Association was held
at Anderton’s Hotel, E.C. There was a large number of members
present, and also many representatives of wholesale houses from
the principal towns in England, the proceedings being charac¬
terised by considerable enthusiasm. The following officers were
elected for the ensuing year: — President: Mr. W. Jones, Bir¬
mingham. Vice-Presidents : Messrs. H. J. Hall, A. Tebbutt, and
H. W. Seeley. Treasurer : Mr. G. R. Barclay. Secretaries :
Messrs. W. S. Glyn- Jones and W. Johnston. Executive Committee :
— Messrs. W. A. Gilligan and J. E. Garrett (manufacturers) ;
C. Sanger and B. Hurst (wholesalers) ; A. Cooper and W. R.
Barnes (retailers), and the officers of the Association as ex-officio
members. It was also decided to add to the Council three
manufacturers, three wholesalers, and three retailers connected
with the photographic trade ; these gentlemen to be elected by
the members of the Association belonging to the respective
sections. The new President, Mr. Jones, then took the chair, and
moved the adoption of the
First Annual Report,
which gave a brief history of the Association , showing that the
first year of its existence has been one of very substantial progress.
The financial statement showed an income of £677 8s. 8 d. , and a
balance of £52 10s. 5 d. — Mr. J. T. Barrett (Leamington) seconded,
and Mr. R. A. Robinson supported the motion. — A number of
speakers followed, all of whom extolled in more or less laudatory
terms the efforts of the P. A.T.A. One or two chemists who spoke
were inclined to condemn the Pharmaceutical Society because it
bad not taken up the matter of regulation of prices, and even
went so far as to assert that it was the duty of the Pharmaceutical
Society to do so, and that the P.A.T.A. movement should have
been initiated by the Society. The Chairman, however, intervened
by calling attention to the fact that this work was not within the
province of the Pharmaceutical Society. — Mr. Glyn-Jones after¬
wards took up the subject, and referring to the Pharmaceutical
Society, he said that although the matter of prices could not be
taken up by the Society as a body, yet, as individuals, members
of the Council could do much to help the P.A.T.A., and he main¬
tained that if the councillors and members of the Society would
show their practical sympathy with the movement, such a step
would do more to improve the position of the Society than any step
they could take. Mr. Glyn-Jones then spoke of the position of
the Association, and he thought it had reached such a point that
it could no longer be termed, as it sometimes was, a “weakling”
Association. A membership of 2060 retailers, all determined by
fair and legitimate means to support the objects of the Associa¬
tion, was not to be despised by the proprietors of various articles.
If, howevtr, the present methods of procedure did not cause manu¬
facturers to join the P.A.T.A., stronger measures would have to
be adopted, and instead of simply retailing proprietary articles
the Association must commence to manufacture similar articles.
This step, Mr. Jones thought, would bring manufacturers to a
different state of feeling towards the Association.- — Mr. Wakefield
■(Birmingham) congratulated the Association on its prosperity, and
on its having secured so energetic and capable a Secretary as Mr.
Glyn-Jones. In the course of a humorous speech he stated that
at a recent meeting of Birmingham chemists they had decided to
close their accounts with several firms who had intimated their
unwillingness to join the P.A.T.A., and only that week the
representative of one of these firms had called on his firm, and for
the first time for many years had left without an order. Seeing
that the annual account amounted to something like £1200, he
thought that particular firm would reconsider its decision to keep
out of the P.A.T.A. The Association must take a firm stand, and
so find out who were its friends and who its foes, and then a civil
war would have to begin. — Mr. Williams (Grocers’ Federation,
Manchester) also spoke in high terms concerning the efforts of the
P.A.T.A., and urged upon all present the necessity of personal
work on behalf of the Association, and suggested that every
member should devote at least one day a week to canvassing for
new members amongst their neighbours. — Mr. Gadd (Evans, Gadd
and Co. , Exeter), as a representative of the wholesale trade, advo¬
cated the claims of the P.A.T.A., and mentioned that his firm in
joining the Association had spelt “ self ” in capital letters and had
no reason to regret the step taken. He warned those present of
the danger of being carried away by an enthusiastic meeting such
as that had been, and then going home thinking all would go well
without their individual help. — The resolution before the meeting
was then put and carried unanimously. Votes of thanks to the
retiring officers of the Association concluded the business.
Nottingham and Notts. Chemists’ Association, Wed¬
nesday, March 31. — Mr. Councillor R. Fitzhugh in the chair. — At
this meeting, called to consider the proposed alterations in the
bye-laws of the Pharmaceutical Society (see ante, p. 306a), a reso¬
lution expressing continued confidence in the Proprietary Articles
Trade Association was unanimously adopted on the motion of Mr.
Gascoyne, seconded by the Vice-President, Mr. A. Middleton.
Liverpool Pharmaceutical Students’ Society, Thurs¬
day, April 1. — Mr. John Jones, President, in the chair. — Mr.
Wokes gave his experience in dispensing a mixture of
Ferri et Quinine Citras and Potass.® Citras.
When the salts were mixed in a small bulk of water after solution
a precipitate was at once formed. This was found not to be due to
alkalinity of the potassas citras, but to concentration of the solutions
used, for when mixed together in a more diluted state the reaction
did not take place. The same phenomenon had been observed by
Mr. Lean and other members. — Mr. Morgan then proceeded
with his lecture upon —
Some Assistants I Have Met,
in which he enumerated the varieties and attempted to classify in
a very original manner the eccentricities of the modern pharmacy
assistant, illustrating his remarks by references to various
humorous episodes which had come under his notice at different
times. The foibles of both masters and assistants were hit off in
an exceedingly happy manner, and notwithstanding the somewhat
delicate ground traversed, the lecturer succeeded in his endeavour
to administer some good lessons without unduly treading upon
the toes or wounding the susceptibilities of his appreciative audience.
Several items of vocal and instrumental music rendered by
Messrs. Cooke and Benn served to lend additional variety
to the lecture, which was one of the most enjoyable in the
history of the Society, and at its close a good discussion took
place, leading to more experiences being related by the members.
— The President next introduced a discussion on the
Proposed Neiv Bye-laws of the Pharmaceutical Society,
expressing a hope that all present would assist in making their
views known, and so thoroughly threshing out a subject
of the gravest importance.; — Mr. Prosper H. Marsden ex¬
pressed his entire agreement with the alterations proposed, for
he regarded the Pharmaceutical Society as the “trade union” of
the retail drug trade, and consequently held that it was justified
in getting from its “journeymen,” on their presenting themselves
for approval, such fee or fees as would best enable it to carry on
the work it had to do, to the satisfaction of the duly elected repre¬
sentatives of the trade — that is to say the Council — who directed
its operations. The Preliminary examination as it was at present
was not worthy of any body of men wishing for the recog¬
nition of the professional status of the pharmacist, and such
a recognition would only be possible by the institution of
a more rigorously applied test of preliminary general education
than that at present in force. — Mr. J. Smith, local secretary of the
Pharmaceutical Society, said that the reason for the increased
examination fee for the Minor was stated in the trade journals to
be that the production of the Pharmaceutical J ournal caused a loss
to the Society of something like £3000 a year. Well he, for one,
should be very sorry to see the Journal return to its former state,
as it was before the recent improvements. Formerly it was a
scientific journal pure and simple, but now
It was of such General Interest,
it was so independent of the necessity of toadying to ad-
322
PHARMACEUTICAL JOURNAL.
[April, 10, 1897.
vertisers, and so impartial, that it was second to none. The
increase of the fees was absolutely necessary to the maintenance
of the Society, for at the present rate the income was not
enough to meet current expenses, and unless something were done,
and that quickly, the Society must soon collapse for want of funds.
Such a thing would be fatal to the whole trade, both outside and
inside of the Society ; for it must be remembered that the work¬
ing of the regulations affecting the practice of pharmacy was
watched by the Pharmaceutical Society, not for the exclusive
benefit of its members alone, but for that of the whole body of
chemists. Students, therefore, by paying the proposed increased
fee, would be only doing their duty to themselves and to the
Society, which was the true guardian of their interests.
- — Mr. Cowley was of opinion that the ten-guinea fee
•would not lessen the number of candidates for examination,
nor would it, as some thought, prevent men from joining the
Society when they passed. Possibly it might be a hardship to the
poorer students, but in his experience these were but a small
minority of the students generally. He would echo and
emphasise the remarks Mr. Smith had made with reference to the
Pharmaceutical Journal, It certainly was
The Premier Trade Organ,
both as regards the scientific matter it contained, its trade reports,
and the manner in which the meetings of the various societies
were written up, and he should be very sorry to see it lapse from
the present high position it had taken up. It had a high tone
to maintain and a position to keep up which the other journals had
not, and was in his opinion well worth the annual subscription. —
Mr. Wokes said everyone was decided as to the necessity of an
increased Preliminary examination, and the increased Minor fee
was just as necessary, so as to cause registered persons to contri¬
bute to the expenses of the Society. — The President thought that
there was a good deal of blame due to the Pharmaceutical
Society for apathy in the past, as it was largely due to its luke¬
warmness in properly advertising itself and the good work; it had
done, that such a small minority ( sic ) of chemists were enrolled in its
ranks. A visit from a local secretary did more towards getting a
man to join the Society than any amount of printed circulars. As a
student of the Pharmaceutical Society, Mr. Owen Davies concurred
in the increased fee, but thought that the method of conducting
the Minor examination was open to a good deal of adverse criticism,
which would to a great extent be removed by the adoption of some
such system as that in vogue as regards the Major. — Mr. Harold
Wyatt, junior, wished to remind the members that the business on
the agenda wa3 the discussion of the proposed alteration of the
bye-la wg of the Pharmaceutical Society, and not a discussion of the
financial affairs of the Society. These latter were matters for the
consideration of the Council, and not for a Students’ Society.
The proposed syllabus for the First examination was modest
enough, in all conscience, in fact, too modest when one con¬
sidered what was demanded of other professions nowadays.
However, a little advance was something, and the one proposed
would help to reduce the percentage of failures in the Minor, which
were mostly due to insufficient early education, a fact as to the
truth of which both Mr. Cowley and Mr. Marsden could bear wit¬
ness. The ten-guinea fee for the Minor was by no means excessive
when one took into account what a man got for his money, and
seemed to be the only way of making sure that each registered
man should contribute his proper share to the Society looking after
his interests. He could not take the gloomy view of affairs that
Mr. Smith did, for whether the ten-guinea fee became a reality
or not, he was certain that
The Pharmaceutical Society would not become Extinct.
It was the only legal representative of chemists and druggists
generally, and the only one bearing any weight with the
authorities. Any legislative measure introduced or passed on
behalf of chemists was due to the initiative of the Society,
and of it alone, and without its help and official support the
greater bulk of the trade not connected with the Society would
find little or no chance of getting any measure whatever through
Parliament, for it must always be remembered that a small well-
organised body can do more than a considerably larger one lacking
organisation. If members of the trade were of the opinion
that the Society as at present governed was not sufficiently
careful of their interests, let them join the Society, qualify
for votes, and then by appointing representatives prepared
to obey their desires, the operations of the Society could be
directed in any direction required. The increased fee was by
some stated to bring the cost of becoming a chemist to almost
that of obtaining a medical qualification, but this was far from
being the case. If a pharmacist in England had to go through
the same course of study as was required on the Continent it would
be true, for there he must, at any rate in the Latin countries, pass
a first examination equal in stiffness to the London University
matriculation examination, and after that, put in a course-
of lectures at a school of pharmacy or university, covering
something like three years before finally being qualified. Even
after qualification he was not free from further expense, for he
was usually called upon to pay a yearly contribution or tax if
in business. After all this a man might, with some degree of
reason, expect recognition of his professional status, but in
England as examinations now stood, such a demand was, to-
say the least, a bit of a farce. The evident desire of the Society
being to so strengthen its hands by the adoption of these new
bye-laws as to be in a position to effect further changes for the
good of the trade, he would move the following resolution : —
“ That this meeting wishes to put on record its appreciation of the bye-laws
proposed by the Pharmaceutical Society, as being the best means of raising-
the status of the pharmacist.”
This was carried unanimously, and a very successful meeting
then came to a close.
Chemists’ Assistants’ Association, Thursday, April 1. —
Mr. Charles Morley, President, in the chair. — The Association,
on this occasion, met for the first time in its new home at 9, Queen’s
Square, W.C. The house is of very ancient build, with oak floors
and panelled walls, mahogany doors and carved mantel-pieces, and
at one time was the town residence of Lord Chesterfield. It is
supposed that within its precincts he wrote the celebrated letters
to his son, and was there visited by Dr. Samuel Johnson. Seventeen
members and one patron of the C. A. A. assembled in one of the front
rooms of this noted house to hear a paper on—
“ The Iodine Value of Beeswax,”
by Mr. It. Glode Guyer, which, however, was taken as read (see
p. 308), and to discuss the
Proposed New Bye-Laws of the Pharmaceutical Society.
Mr. Morley commenced by remarking that this subject was one
of very great interest to pharmacists generally, but more especially
young pharmacists, because they would feel the benefits or bad
results of the passing of the proposed bye-laws. The Chemists’
Assistants’ Association naturally took a great interest in the bye-law-
relating to the Preliminary examination, seeing that the proposed
alteration was probably in some measure due to a resolution passed
by the Association about five years ago, when the members felt that
the present Preliminary test was by no means an adequate one for
testing the capabilities of the youths desirous of entering phar¬
macy. It was now proposed to introduce subjects such as Euclid
and Algebra, but Mr. Morley thought in addition to these it would
be a great advantage if a little knowledge of elementary physics
and chemistry was also required. As that Association had sug¬
gested and moved a resolution which was forwarded to the Phar¬
maceutical Society to the effect that the Preliminary exami¬
nation should be increased in stringency, he thought it
behoved them not to be slow in showing that the
members were still imbued with the same progressive spirit as
the men were five years ago. Mr. Morley was of opinion that the
Preliminary should be made compulsory before apprenticeship.
With regard to the increased Minor fee he thought the question to
consider was whether the sum was more than sufficient to provide
permanent registration and to indemnify the Society in protecting
the whole trade against unqualified traders. He believed it was not
too much for this purpose, although he did not quite agree with the
ten-guinea fee being charged a second time when a man failed ; a
three-guinea fee would in that case be sufficient. However, he
had much pleasure in moving the following resolution
“That this meeting approves of and strongly supports the action of the
Council of the Pharmaceutical Society in framing the proposed new bye-laws,
being of opinion that these are calculated to serve the best interests of phar¬
macy.”
— Mr. C. J. Strother held much the same views as Mr. Morley,
and formally seconded the motion. — Mr. T. Morley Taylor
thought the increased fee was somewhat unfair to certain members
April 10, 1897.]
PHARMACEUTICAL JOURNAL.
323
of the community, namely, the fairly well-educated men who,
while not being possessed of a superabundance of money, were
loyal to the Society, and who meant when qualified to support the
Society. The qualifying examination was one at which it was so
extremely easy to fail that it would fall rather hard on .them.
He agreed with a £10 10s. fee, but thought that £5 5s.
should be paid for the examination, and £5 5s. on qualifying. —
Mr. E. W. Hill was in entire sympathy with the proposed bye¬
laws. He did not consider the £10 10s. fee at all an excessive sum
to pay for registration and the protection a man secures on
■qualifying. The second £10 10s. at the end of two years was also
not excessive, he thought it was the man who could pass who was
to be considered, and not the man who could not pass. Many
men came up for examination before they were properly prepared,
and he thought the increased fee would weed out a great many of
them. — Mr. MacEwan was astonished to find not a substantial
argument brought forward in respect to the increased Minor fee.
The question seemed to be put in the sphere of ethics, whereas it
was entirely a matter of economics ; if the Society were not hard
up he thought it would not have asked for the increased fee.
He thought Mr. Morley was hardly consistent in moving the
resolution he had, inasmuch as he was not altogether in accord
with the ten -guinea fee. Mr. MacEwan considered that the
extra five guineas was not required by the Society to carry on
its public work, but to aid it in its private capacity. —
Mr. C. E. Robinson thought the increased Minor fee would pre¬
vent many men coming up for simply a “ flutter ” at the examina¬
tion in the hope of passing, and that they would work much
harder to prepare themselves. — Mr. A. R. Melhuish agreed with
£he step in regard to the Preliminary examination, and with the
increased Minor fee, except that he considered it should not be
charged a second time. He therefore moved that the resolution
■Re amended by the following addition : —
•“ Except that it considers that the fee of £10 10s. should not be charged more
than onee, and that the time limit when this bye-law comes into operation
should be extended from 1898 to 1900.”
With regard to Mr. MacE wan’s remark that no argument had
Been put forward in favour of the increased fee, he thought it
would be good for the trade as a whole, because anything that
tended to strengthen the Society must tend to raise the status of
all in the trade. — Mr. G. Roe thought that if the private expenses
-of the Society were more than its private income they should be
curtailed, but with regard to the £10 10s. fee he did not think
it a large sum considering the dignity of the profession,
and he did not think it would deter any lad from getting through
his examinations. During Mr. Robinson’s and Mr. Melhuish’s
remarks, the discussion degenerated into an argumentative
conversation amongst those present, owing to interruptions by
Mr. MacEwan, who, contrary to all rules of debate, persisted in
-endeavouring to correct (?) the speakers as they proceeded. — Mr. R.
• G. Guyer, who looked at the question from the ethical side, seconded
the amended resolution, and after a few remarks from Mr.
Summers, who thought most of the speakers had been “beating
the air ” instead of dealing with the main question, Mr. Morley
replied, and the question as to whether Mr. Melhuish’s amend¬
ment should be tacked on to the resolution was decided by six
•votes to four, the amendment being carried. The amended reso¬
lution was then put as follows
“ That this meeting approves of and strongly supports the action of the Council
of the Pharmaceutical Society in framing the proposed new bye-laws, being
-of opinion that these are calculated to serve the best interests of pharmacy,
-except that it considers that the fee of £10 10s. should not be charged more
•than once, and that the time limit when this bye law comes into operation
should he extended from 1898 to 1900.”
'Six voted in favour of this and two against, whilst nine refrained
from voting.
Glasgow and West of Scotland Pharmaceutical
.Association, Thursday, April 1. — Mr. W. L. Currie, Presi¬
dent, in the chair. — This was the annual business meeting of the
Association. — Mr. J. Anderson Russell, Hon. Sec. and Treasurer,
^submitted
The Council Report.
It stated that during the year the Association had continued to
make steady progress. The membership was now 181, being a net
increase of 26 as compared with the previous year. There were 126
members in the city, of whom 74 were in business and 52 assis¬
tants, and there were 55 country members. Greater interest was
being taken in the Association, particularly by the younger
members. It was felt that if the proceedings could be commenced
at an earlier hour a considerable increase in the attendance
would result, and an appeal was made to the members to
bring about this. Reference was next made to the work which
had been done during the session and to the fact that the British
Pharmaceutical Conference would be held in Glasgow this
summer. The gratifying fact was also mentioned that the
members had appreciated the social functions, and that closer
fellowship and interest in each other had resulted. The
Association was now a good working organisation, and the
Council impressed upon members the desirability of endeavouring
to make it what they all desired it should be. They began the
year with a reserve capital of £50 4s. 7 d. The receipts during the
year amounted to £70 3s., making a total of £120 7s. Id. The ex¬
penditure during the year was £60 8s. 3c?., leaving a balance of
£59 19s. 4c?., an increase of £9 14s. 9c?. on the year. In these
accounts the statement of the social committee showed a deficit
of £8 12s. on the year, but the year was started with a
balance in hand of £4 15s., so that the deficiency
in the accounts of the social committee was £3 17s.
At the “Annual Sociale” there was a larger attendance
of members of the trade but a lesser attendance of outsiders.
— Mr. Thomas Robinson moved that if it were decided to
have an “At Home” next session, a small charge should be
made for admission.- — Mr. Alexander Laing seconded. — Mr.
Blair moved that the Association do not depart from their custom
of having the “At Home” gratis. — Mr. D. Watson, in seconding,
said that to make a charge for admission to the “At Home”
would limit the scope of the Association, as it had been the
means of increasing the membership. He thought that
the matter should be left in the hands of the Council,
and after some further discussion, the amendment was carried.— On
the motion of Mr. Dunlop, seconded by Mr. Boyd, the reports by
the Council and the Treasurer were adopted. — The Chairman said
he had been very much impressed during the session by the
marked improvement in the attendance of the younger members,
but it could be very much better. Several of them had come to
the front with papers which showed a talent they did not pre¬
viously know existed. If the labour had been great in getting up
these papers it had been appreciated in no small degree, and
while they had imparted a great deal of knowledge to the other
members, they had reaped much benefit themselves.- — Various
votes of thanks having been passed, Mr. Russell said, with
regard to the forthcoming meeting of the Federation of Local
Associations, he suggested that their delegates should see that
there was some definite method adopted for bringing business
before the procedure, as there seemed to be a doubt as to what
procedure should be adopted.
Election of Officers.
The following office-bearers were elected : — Hon. President, Mr,
Daniel Frazer; Hon. Vice-Presidents, Messrs. John McMillan,
Alex. Kinninmont, and J. W. Sutherland ; President, Mr. W. L.
Currie ; Vice-Presidents, Messrs. John Foster, Alex. Laing, James
Robb, and J. Anderson Russell ; Hon. Secretary and Treasurer,
Mr. D. Watson, Cathcart Road ; District Secretaries, Messrs. A.
McKellar (South Side), M. Gray (Partick), A. Miller (North-
East), and M. Wallace (North - West) ; Librarian, Mr.
David Moir ; Committee, Messrs. Hugh Lambie, Alex.
Boyd, Robert Brodie, Thos. Adam, Alexander Bruce,
John Neil, D. S. Robertson, James McMurray, Robert
Tocher, J. Arnott, Thomas Dunlop, J. Abbott, A. Fraser (Paisley),
T. Kerr (Greenock), and P. Mitchell (Dumbarton). Auditors :
Messrs. James Moir and James Bruce. — Mr. Rae moved and Mr.
Macadam seconded that the night of meeting be changed from
Thursday to Friday. — Mr. Laing moved the previous question.
Ultimately it was remitted to the Council with power to deal with
the matter and also to arrange as to the hour of meeting.
Potassium Bichromate as an Expectorant. — Weaver finds
the following useful in laryngitis and bronchitis, and especially in
tonsilitis. In the former a teaspoonful of a solution of 1 grain of
potassium bichromate in fiii, or §iv. of water, but in the latter
the finely-powdered bichromate should be added to the water
until the latter is a dark lemon or light orange shade ; of this a
teaspoonful is given every hour. — Ind. Jcmrn. Phar., iii., 221., after
Med. Rev.
£24
PH ARM ACEU TIC AL JOURNAL.
[April 10, 1897
PHARMACEUTICAL SOCIETY.
MAJOR EXAMINATION QUESTIONS.
A Paper.*
BOTANY AND MATERIA MEDICA.
Saturday, April 3, 1897. — 10 a.m. to 1 p.m.
1. What are the most striking external characters of any five of the following
plants ? —
Willow, Poplar, Oak, Beech, Fir or Pine, Plane.
2. Give an account of the .structure of the female flower of any Conifer, with
a careful description of the structures formed in the embryo-sac, before and after
fertilisation.
3. By what experimental methods has our knowledge of the essential con¬
stituents of the food of a green plant been obtained ?
4. What is Nux Vomica? Give the name of the plant from which it is obtained
and state its Natural Order and habitat. What are its principal constituents,
and in what proportions do they exist ?
5. How is Cherry Laurel Water prepared ? To what is its medicinal activity
due ? Explain how this is produced.
B Paper.*
BOTANY" AND MATERIA MEDICA.
Saturday, April 3, 1897. — 2 to 5 p.m.
1. What are the most striking external features of any five of the following
flowers ? —
White Dead-nettle, Larkspur, Spurge, Hemlock, Pine or Fir, Wall-Flower,
Pansy.
2. Describe the structure of the anther of an Angiosperm, and compare it with
that of the corresponding organ of a Conifer.
3. By what means and in what form do roots absorb the mineral elements of
the plant’s foods ?
4. How and where is opium produced ? How may the commercial varieties
he distinguished? Mention its principal constituents.
What method should you adopt to estimate its value? Explain the process.
5. What is the “Mustard” of the Pharmacopoeia? What are its principal
constituents? Explain the change which takes place when the powder is
moistened with water.
B Paper.*
PRACTICAL BOTANY AND MATERIA MEDICA.
Saturday, April 3, 1897. — 10 a.m. to 1 p.m.
1. Prepare longitudinal tangential, and radial sections of the stem A. Sketch
your preparations, labelling the various parts, and point out such features as
are characteristic of coniferous wood.
2. Befer each of the flowers B and C to its Natural Order, giving your reasons.
3. Identify the drug provided, and display its histological features.
Leave a section and a lettered sketch explaining it.
4. Investigate and report upon the powder.
A Paper.*
PRACTICAL BOTANY AND MATERIA MEDICA.
Saturday , April 3, 1897. — 2 p.m. to 5 p.m.
1. Prepare a transverse section of the stem A ; make a careful drawing of your
preparation, and name the several structures shown, pointing out such evidence
as exists of secondary thickening.
2. Befer each of the flowers B and C to its Natural Order, giving your reasons.
3. Identify the drug provided, and display its histological peculiarities.
Leave a section and a lettered sketch explaining it.
4. Investigate and report upon the powder.
CHEMISTRY.
Monday, April 5, 1897. — 10 a.m. to 1 p.m.
[<SYr questions only are to be attempted .]
1. What are the principal reactions exhibited by sulphurous, thiosulphuric
and hydrosulphurous acids or their salts ? Indicate the practical use, made of any
of these reactions.
2. You are given some common salt. Describe in detail how you would pre¬
pare from it pure sodium chloride, sodium nitrate, sodium nitrite, glauber salt
and sodium disulphate respectively.
3. What weight of phosphorus is contained in 500 C.c. of a normal solution
of hypophosphorous acid ? State what you know of the action of heat on hypo-
phosphites.
4. How is potassium platinocyanide prepared ? State what you know of the
optical character of crystals of platinocyanides.
5. What is the constitution of mustard oil ? How may it be prepared artificially ?
6. What is the action on benzaldehyde of (a) hydrocyanic acid ; (6) strong nitric-
acid ; (c) phosphorus pentachlori.de ; (cl) ammonia ?
7. You are given a mixture of benzene, phenol, and salicylic acid. Describe
how you would separate each ingredient in a pure state from the mixture.
8. How is the existence of four isomeric tartaric acids accounted for? Indicate
how from any one the other isomers can be obtained.
9. Give examples of any ring-compounds which can be synthesised from urea.
* Part of the candidates received the papers A, A, and others had the
papers B, B.
PHYSICS.
Monday, April 5, 1897. — 2 to 5 p.m.
[Six Questions only are to be attempted .]
1. When a current of air is passed through a volatile liquid the rate of evapora¬
tion is increased and the temperature diminished. Explain both effects.
2. What are the relative advantages and disadvantages of air and mercurial
thermometers ?
3. Describe briefly two distinct classes of phenomena which are best explained
by the undulatory theory of light.
4. Why does reflection at a plane mirror apparently change a man’s right hand
into his left, while not interchanging his head, and his feet ?
5. What methods are employed for producing magnetism ? Describe how you
would make a horse-shoe magnet, and the kind of metal you would use.
6. Describe ail electroscope and the mode of using it.
7. Describe some chemical effects produced by an electric current.
8. What is meant by the term “ extra-current,” and how is it produced?
9. Descx-ibe precisely how you would proceed if you were required to determine
the electrical resistance of a piece of copper wire.
PARLIAMENTARY NOTES AND NEWS-
The Second Reading in the House of Lords of the Preferential
Payments in Bankruptcy Act (1889) Amendment Bill reminds one
that that useful amending measure is now within reach of the
Statute Book. Its object is to confer on the employes of bankrupt
companies the same preference rights as to the payment of wages
and salaries, which the workmen and clerks of individuals enjoy
under the Bankruptcy Act of 1888. After the enactment of the
amendment, wages and salaries will have priority over payments
to debenture holders or other creditors.
Mr. Ritchie has again expressed his intention of re-introducing
the Metric Weights and Measures Bill of last session. This time
it was in answer to Mr. Crombie (Kincardineshire) that the
announcement was made, but Easter is near and the Bill does not
appear.
Mr. Lloyd George (Carnarvon Burghs) last week carried out
his promise of calling attention to the horribly overworked condi¬
tion of the Local Government Board and to the difficulty of
getting questions dealing with the Department attended to. He
pointed out that the Board had power under its Act of 1888 to-
delegate some of its duties to local Councils, which could deal
with purely local questions much more efficiently. Such items as
boundaries, and sale of drugs were quoted as instances in which
the Board might very properly try a little decentralisation. The
President of the Board, in reply, admitted a truly deplorable
state of chronic over-pressure, which had made it impos¬
sible to close some of the audit accounts within the financial
year. The Departmental Committee appointed to inquire into the
whole question of the organisation of the Department (see Ph. J.,
Dec. 19, p. 534) had agreed upon a report of a satisfactory nature, and
there was ground for hoping that all cause for complaint would in
time be removed. Mr. Chaplin proved that the Department was
not averse to the devolution of certain work upon County Councils
by referring to an attempt in 1889 to bring in a Bill effecting it.
But the non-county boroughs would have none of it.
Petroleum Committee. — -Mr. Robert Shaw was the witness on
March 31, and, as became the manager of the Liverpool branch of
the Anglo-American Oil Company, testified to the superiority of
American oil, so far as safety and method of conveyance was con¬
cerned. The chief part of the evidence was directed to showing
that further legislation in respect of petroleum was quite unneces¬
sary. Of course, the witness added, there would be little objection to
legislation which would secure a general adoption of the “ tank
system, and he had no objection to the registration or licensing
of dealers, but he was strongly opposed to any registration fee being
charged. No fee was charged in the case of milk dealers, and Mr.
Shaw could not see that the difference between milk and oil made
any difference in principle. Mr. Shaw was very emphatic with
this part of his evidence, and stated that in his opinion the
smallest registration fee would drive numbers of dealers from the
trade. Petroleum must be worse than pharmacy !
The Sale or Food and Drugs Bill has been further deferred
till April 29, and the Shop Assistants (Half-Holiday) Bill till
Wednesday 28th inst.
Apeil 10, 1897]
PHARMACEUTICAL JOURNAL.
325
LETTERS TO THE EDITOR.
The Forthcoming Council Election.
Sir, — Allow me to supplement the letter of Mr. Gostling in last
week’s Pharmaceutical Journal by saying how fully I endorse what
he has so well said, as to the desirability of increasing the proportion
of London members on the Council. As at present constituted
there are only five out of a total of twenty-one. There must of
necessity be a large and probably growing amount of routine work
to be done by those members within easy reach of Bloomsbury
Square, and it seems to me that the interests of the Society would
be better served if the number were increased to six or even seven.
As a provincial member of the Society it would ill become me
to speak lightly of the services so ungrudgingly rendered
by the country members, who, at the sacrifice of so much
time and strength, give us the benefit of their experience, and who,
in some respects, perhaps, represent and understand the difficulties
of the retail trade better than our London friends. Still this does
not prevent my seeing the great advantage that must accrue to
the Society in having non-members available on special occasions
for administrative work. Those of us who are accustomed to
public work know how important it is to be able, when some
sudden emergency occurs, to confer with colleagues ; this is
impossible when they are at a distance. While the chief business
of the Society must of course be done at the monthly meeting of
the Council, when all are present, it is not less important I think,
that these informal conferences should be well provided for. W e
in Bristol have so long been accustomed to have one of our own
number (in the person of the late G. F. Schacht) on the Council
that it has frequently been said we ought to take some steps to
secure a successor (so to speak). I should have been inclined to try
and secure the nomination of one of my colleagues at this election but
for the feeling I have that the proportion of provincial members is
already too large. I hope the members of the Society will give
due weight to these considerations when filling up their voting
papers. May I also be permitted to say that I trust there will be
less apathy displayed at this election than on some former occa¬
sions ? We are a democratic body, and can choose whom we will
to represent us.
Bristol, April 6, 1897. B. Keen.
The Peoposed New Bye-Laws.
Sir, — No reasonable objection can be urged against the proposed
change in the Preliminary examination. Ten guineas, when looked
upon as an examination and registration fee combined, is not ex¬
orbitant, but it is enough without exacting large sums from can¬
didates on their coming up againfor examination after having failed.
W hy not make the qualifying examination progressive for those
who fail in one or more subjects, by allowing them to pass in those
subjects in which they may have obtained the requisite number of
marks, and for every subsequent appearance before the examiners,
let one guinea be charged for each subject in which the candi¬
date is examined? By this means young men would be able
to devote more time to those subjects in which they found them¬
selves deficient, and besides, it would tend to remove the reproach
so often levelled against the Society (but so seldom justified. —
Ed. Ph. J. ), viz., want of sympathy and consideration for those
entering the profession.
Hawick, March 31, 1897. W. S. Turnbull.
“ A Member of the Pharmaceutical Society ” (88/35), apparently
under the impression that the Council has not already fully
considered the matter, suggests that the fee for the qualifying
examination and the registration fee should be distinct and paid
separately. He appears to think also that payment of the second
fee should constitute the newly-fledged chemist and druggist a
life associate of the Society. Similarly, he would make all
pharmaceutical chemists life members.
Sir, — The letter of “K. K.” in the Journal for March 27, brings
before the Council a want long felt by pharmacists and apprentices
in town and country alike. The proposed examination should be
thoroughly practical, including dispensing, a knowledge of the
Pharmacopoeia preparations, with doses of the same, as well as doses
of poisons, and antidotes of the same. Such an examination every
apprentice should be able to pass at the expiration of his apprentice¬
ship, and become the holder of an assistant’s diploma, to act as such
to a qualified chemist, under the supervision of the latter, but it
should not permit him to manage a business, branch or otherwise ;
this should only be doneby a fully qualified person. An examination
somewhat on these lines would, I think, be a boon to apprentices, for
having tasted the pleasure of study, they would be induced to put
forth further efforts to qualify ; to their future employers it would
be a certificate that they possessed practical knowledge of the duties
required of them, whilst the Society itself would be the gainer by
increased numbers, extended usefulness and influence.
April, 6, 1897. T. T. (88/39).
Public Service Dispensers.
Sir, — The two main complaints of the public service dispensers
are : largely increased duties, and miserably inadequate salary. It
is now common knowledge that the average dispenser is compelled
to work at dangerously high pressure in the ordinary dispensary
routine, and is called upon to perform highly technical duties
rendered necessary by the greatly increased activity displayed by
the medical officers in research work ; and all this for a salary
very little in excess of that received by a journeyman bricklayer.
While all other workers obtain salaries advancing with the times,
the unfortunate dispenser is now only in receipt of the same, and
in some cases less than twenty years ago. Individual protest is
useless, we are simply told that “if your position was vacant we
could obtain another to do your duties at less money.”
So long as we are content to labour on for a mere
existence, no one will trouble to interest themselves in our fate.
We must exert ourselves, meet together, form a strong association,
and firmly and plainly place our position before the governing
bodies, asking for the justice that could scarcely be refused
us. Of no other skilled worker is so much expected while so little
is given. Of no other is such an extensive range of miscellaneous
requirements exacted. No other is expected to be always ready,
willing, and able to turn his hand to anything that science or art
suggests, and yet to manage his department with efficiency and
economy. Because we have always seemed to be contented with
our lot may have been an excuse. Let it be so no longer. Let it
be seen that there are others who consider ‘ ‘ the labourer is worthy
of his hire” besides —
April 2, 1897. “A Fifteen Years’ Dispenser” (88/13).
The Dose of Tincture of Strophanthus.
Sir,— On Friday of last week I met a medical friend, who told
me that on the previous day he had prescribed for a woman about
forty years of age suffering from an affection of the heart 1 oz. of
the tincture of strophanthus. Although the label bore that the
dose was to be 10 drops, his patient took a teaspoonful, and repeated
this three hours afterwards. The next morning the prescriber
found the quantity that had been taken and inquired as to the
condition of the patient ; she had passed a good night, and was
altogether in a better condition. The strophanthus was not
dispensed by my firm, but along with the medical
gentleman I called at the establishment where it was
dispensed. In physical appearance and taste it seemed in
every way satisfactory, and had been purchased from a good firm.
As a teaspoonful is a very uncertain quantity, at my suggestion a
messenger was sent to the patient for the bottle, and the contents
being measured five drachms was found to be the quantity left, so
that within three hours three drachms had been taken. At the
time of taking the strophanthus the patient’s bowels were somewhat
relaxed, so that full absorption would not be likely to take place.
I further suggested to my friend that he should communicate the
facts to Dr. Fraser, of Edinburgh, which he intends doing. The
facts connected with the case should be of interest to youJt
readers, and I shall be glad to know if any of them have had any
experience as to what constitutes a poisonous dose of the drug.
Greenock, April 6, 1897. Archibald MacNaught.
The Dose of Creosote.
Sir, — It may be of service to some of our friends in the trade to
know that creosote can be given in very large doses. We have
patients at the present time taking up to 40 minim doses three
times a day. Of course this has been progressive. I write simply
by way of information, because one of our physicians told me a few
days ago that he had had a prescription returned to him for con-
fimation which contained but six minims to the dose. This was
thought by the chemist to be an overdose.
London, April 6, 1897. W m. Harvey.
326
PHARMACEUTICAL JOURNAL.
[April 10, 1897.
ANSWERS TO QUERIES.
Special Notice. — Scientific, technical, legal and general information required
by readers of tlie ‘Pharmaceutical Journal' will be furnished by the Editor as far
as practicable, but he cannot undertake to reply by post. All communications must be
addressed “Editor, 17, Bloomsbury Square, London, W.C.," and must also be authen¬
ticated by the names and addresses of senders. Questions on different subjects should
be written on separate slips of paper, each of which must bear the sender's initials or
pseudonym. Replies will, in all cases, be referred to such initials or pseudonyms,
and the registered number added in each instance should be quoted in any subsequent
communication on the same subject.
Esbach’s Re-agent. — Dissolve picric acid, 10 Gm., and citric
acid, 20 Gm., in water, 1 litre. [Reply to R. J. P. — 88/12.]
A. P. S. or L. P. S. — It is not a matter of legality but of good
taste, since the title of “licentiate” of the Society is not a recog¬
nised one. [ Reply to J. C. C. — 88/24.]
Botany for Beginners. — Get Scott’s ‘ Introduction to Structural
Botany,’ vol. 1 (A. and C. Black, 3s. 6 d.), and work through it
systematically. [Reply to Student.— 87/43.]
Startin’s Face Lotion. — The formula you require appears in
Startin’s ‘Skin Pharmacopoeia ’ as “ Lotio Zinci Co.” — zinci
oxidi, |ss. ; pulv. calaminse, ; glycerini, §i. ; liquor calcis,
gviii. ; aqua ad. Oi. [Reply to H. B. Q. — 86/14.]
Aperient Syrup.— Liquid extract of cascara sagrada, 2 fl. ozs. ;
compound decoction of aloes, 2 ozs. ; borax, 30 grains ; tincture of
capsicum, 30 minims ; compound tincture of gentian, \ fl. oz. ; oil
of sassafras, 6 minims ; oil of wintergreen, 3 minims ; treacle,
4 fl. ozs. [Reply to M. P. S. — 85/39.]
Microtomes.- — Write to Mr. Abraham Flatters, 16, Church Road,
Longsight, Manchester, about the microtome described by him.
The other is made by Mr. Holt, West End House, Ashton-under-
Lyne. Mr. C. Baker, 244, High Holborn, W.C., also makes small
microtomes for botanical work. [Reply to Arbeiter. — 86,40.]
Remedies for Haemorrhoids.— Cream of tartar, 1 ; powdered
cubebs, 2 ; precipitated sulphur, 1. Mix. Take a teaspoonful in
a little milk night and morning. The old-fashioned remedy of
equal parts of confection of senna and confection of pepper is
also very effective. Locally apply ung. gallse c. opio. Tincture of
horse-chesnut has recently been given internally (Ph. J. [4], iii., 79)
with excellent results. [Reply to M. P. S. — 85/39.]
Plate Powder. — Although mercury and chalk is largely used
in the preparation of plate powders, its employment can scarcely fail
ultimately to injure the plate, since the mercury forms an alloy
with the silver, and a minute quantity of that metal must
necessarily be removed by each friction. It is probably popular
with butlers because it gives a brilliant polish, with a minimum
expenditure of “ elbow grease.” The following has been found to
give very good results Prepared chalk, 8 parts ; jewellers’
rouge, 1 part; diatomos, 1 part ; dried and powdered hyposulphite
of sodium, 2 parts. Mix. Apply wet with a soft rag and polish
off with chamois leather. [Reply to R. H. — 87/1.]
Ice Cream. — Presumably you know the apparatus neces¬
sary for freezing, the pewter freezer, ice pail, and wooden
spatula. In actual practice you will find a mixture of one pound
of rough salt to every three pounds of small ice give the best
results. A good basis is : New milk, 3 pints ; best condensed milk,
1 tin ; yolks of four eggs. Mix and heat gently with constant
stirring to make a custard. Then cool and put into the freezer,
which is packed round with ice and salt. Whirl round for five
minutes. Then take off lid and scrape down the frozen ice off the
sides. Again whirl and scrape, repeating the process until a
uniform butter-like mass results. The above basis can be
flavoured with vanilla, orange, lemon, almond, or any other
flavouring. If you want a specially rich ice, substitute raw cream
sweetened with sugar for the quantity of milk given above. Fruit
ices are made by rubbing good preserves through a sieve and
mixing the pulp so obtained with the custard in the proportion of
one of fruit pulp to two of custard. [Reply to H. R. B. — 85/38.]
English Dictionary. — Get the latest edition of Ogilvie’s
‘Student’s English Dictionary’ (Blackie, 7s. 6 d.), edited by
Annandale. [Reply to J. C. C. — 88/24.]
Photo-Chemicals. — A. and M. Zimmermann, 9, St. Mary-at-
Hill, Eastcheap, E.C., for pyro. and oxalates ; Boake, Roberts
and Co., Stratford, for sulphites and hypo. ; Johnson and Son
or Johnson and Matthey, London, for gold and silver salts..
[Reply to A. A. M. — 87/42.]
Qualification as Associates in Business. — Neither directors
nor shareholders, although actively engaged in the business of
the company, can be said to be carrying on business on their own
account ; consequently they are not eligible for election as asso¬
ciates in business. [Reply to Panto. — 87/8.]
Analysts. — There is a great and growing demand for “com¬
petent” analysts. The best qualification is the Fellowship of the
Institute of Chemistry. Write to the Secretary, 30, Bloomsbury
Square, London, W.C., for particulars, and then you may be able
to form some idea of the cost. [Reply to E. R. B. — 88,23.]
Botanical Works. — Bennett and Murray’s ‘Handbook of
Cryptogamic Botany ’ (Longmans, 16s.) may serve your purpose,
but for extended work you will require special books dealing with
each branch of the subject. Messrs. W. and A. K. Johnston,
of Edinburgh, publish the atlas. [Reply to L. A. R. — 88/19.]
Dispensing Query. — Four emulsion*-calcii oleat. , /jiv. ; lanolin,
3vi. ; fossiline, pii. ; pulv. acacia, gr. 160 ; pulv. acid boric, gr. 32
ol. geranii, tTlvi. ; aq. rosse concent., Jij. — is a little difficult. In the
first place, calcium oleate is an ambiguous term. Possibly the-
writer considers this a euphemism for lin. calcis ; but we do not
think you should depart from the written letter of the prescription,
and should prepare the true oleate of calcium. This is easily done
by mixing 224 grains of oleic acid and 3 fluid ounces of saccharated
solution of lime, which will give you the required amount of calcium
oleate. The mixture is boiled to complete the saponification, and
the resulting lime soap drained,- washed, and dried. This is then
rubbed perfectly smooth on a slab, and incorporated with the
fossiline and lanolin, and the acacia. The boric acid is dissolved
with the rose-water. All are then incorporated together with a.
gentle heat, removing as soon as a homogeneous mixture
results, and stirring until cold, adding the perfume at the
last. Thus treated a smooth homogeneous emulsion results about,
the consistence of thin Devonshire cream. Several other ways
of mixing, in the cold and with heat have been tried, but
the above is the only method which gives a presentable result-
[Reply to A. T. J. — 85/1.]
OBITUARY.
Thomas. — On March 25, John Henry Thomas, Chemist and
Druggist, Chester. Aged 38. Mr. Thomas had been an Associate-
of the Pharmaceutical Society since 1875.
Bagley. — On March 27, Thomas Joseph Bagley, Chemist and
Druggist, Wolstanton, Staffs. Aged 55.
Chessall.— On April 1, Rowland Chessall, Pharmaceutical
Chemist, Sidmouth, Devon. Air. Chessall was an old and much-
respected tradesman, and had been a member of the Pharmaceutical
Society since 1862.
Allis. -^On March 18, Francis Allis, Pharmaceutical Chemist,,
Bristol. Aged 77. Mr. Allis had been a member of the Pharma¬
ceutical Society since 1853.
Staning. — On March 30, Walter Staning, Chemist and Drug¬
gist, Hull. Aged 77. Mr. Staning had been an Associate of the
Pharmaceutical Society since 1871.
Blatchley. — On April 1, Thomas Blatchley, Chemist and
Druggist, Yeadon. Aged 67. Mr. Blatchley was greatly esteemed
in Yeadon, and for a term of three years was a member of the
Local Board. He had been a member of the Pharmaceutical
Society since 1870.
COMMUNICATIONS, LETTERS, etc., have been received from
Messrs. Andrews, Bullock, Butt, Cocks, Cowley, Currie, De Morgan, Dennis, Duyk,-
Farr, Flatters, Forret, Forsliaw, Gibbard, Grimble, Guyer, Harvey, Heap, Herman,
Hill, Hustler, Jackson, Keen, Kent, Lockyer, Macaulay, MacKinna, MacNaught-
Moss, Myers, Pike, Ranwez, Reynolds, Roberts, Robinson, Shattock, Shepherd.,
Squire, Startin, Syms, Tipping, Turnbull, Welford, Wilson.
[Several Letters and Answers are held over.]
PHARMACEUTICAL JOURNAL.
327
IE Li
,o \ 20 APi 97 r
\ ^ /
Mr. George- Cou.Il .has/fead before the Glasgow Pharmaceutical
Association anelaborate paper on the above subject, conceived in
the rwj£ Sjoint oLgmistructive criticism. Apart from pharmacy I
should delight in being purely classical, and in private my pleasure
tends that way ; but as a member of a pharmacopceial committee,
I recognise that purism may be pushed too far, and that we cannot
always with advantage clothe modern remedies in the very words
of Cicero or Pliny.
I have long wished that we could agi’ee to give the usual
grammatical endings to words which from their form might
obviously be classed under definite declensions in order that we
might have an accepted rule respecting the nomenclature of
existing latinised words and of any new remedies that might from
time to time be introduced.
The wish was extremely modest and easy of application, but I
have been but partially successful.
I regret that while we have linimentum saponis and cataplasma
carbonis, we retain tinctura kino ; that while at school we say
animal, animalis, we leave chloral indeclinable and treat other
terminations in the same way.
My failure in this respect is a standing warning not to use long
words. The term nomenclature (four syllables) carries with it a
feeling of alarm lest changes of a recondite or fanciful nature
should be advocated. A decently trained apprentice would have
been competent to write such terminations (not alterations) into
his master’s pharmacopoeia.
In words of Greek origin, requiring higher scholarship, we have
gone right, for we have oleum theobromatis, though oleum theo-
bronue may be found in pharmacopoeias of an earlier date.
As the simple plan mentioned found scant acceptance, I am
afraid there is little hope for the introduction of destoleum,
oleamen, oleamentum, hagenia for cusso, and novelties of that
description.
I venture to make a few remarks on Mr. Coull’s recent contri¬
bution to the subject, not by way of criticism but rather as
running comment on the general question. Gelatinum, in English,
gelatin, is not gluten or glutinum, glue. The writer who proposed
resinum for resina may be left alone ; naptol for naphthol I have
hitherto considered a printer’s error.
Now comes the ever disputed point, the pharmacopoeial gender
of nouns in as, atis, and is, itis ; viewed as classical words the
former are feminine.
The matter seems to stand thus : — Mediaeval writers took the
word sal, salis, as neuter— hence we get a long series of salts as
sal enixum, sal polychrestum, and down to the present day, sal
volatile.
Had this been correct, the plural noun would have been salia,
which it never was, instead of sales which has been universally
adopted. These neuters must be rejected with the exception of
sal volatile, consecrated by immemorial use.
Many writers and some pharmacopoeias followed this nomencla¬
ture, but on the introduction of scientific names the case was re¬
considered. Sal was a noun masculine, and the salts (sales) were
accredited with this gender. The Paris Codex took this view, and
the whole Continent followed suit ; last of all the United States
gave in adherence, while Great Britain, considering the nomen¬
clature as classical, kept to the Latin Grammar and made these
salts feminine.
I can only repeat the sentence I inserted in the eighteenth
edition of Pereira’s ‘ Selecta e Pra:scriptis ’ : “ Great Britain stands
Von. LVI1I. (Fourth Series, Yol. IY.). No. 1399.
alone in considering chemical names ending in as, atis ; is Itis, as
feminine. In Continental practice they are masculine, and it is an
open question wdiether, there being no classical authority but only
the law of custom, British pharmacists should not conform to this
arrangement.”
It is not necessary to fight over rosmarinus ; originally ros
marinus, the genitive would be roris marini, similar to oleum
filicis-maris ; becoming a simple substantive, either rosmarinus or
rosmarinum, it is more correct to write oleum rosmarini than as
formerly, oleum rorismarini.
In the same sentence in the ‘ Pharmacologia ’ we read : olea
rosmarini and rorismarini officinalis ; the first is the term used
by Dr. Paris ; the second by the Edinburgh College. When
Horace wrote “ marino rore” he could do no otherwise, for the
‘ Ode Ad Phidylen ’ is in alcaics, marino being at the end of one
line, and rore at the beginning of the next : — -
Te niliil attinet
Tentare multa csede bidentiuin
Parvos coronantem marino
Rore deos fragilique myrto.
Horace never wrote roremarino, which is the real point. Anti-
monium, it may be remarked in passing, is not a hybrid word, but
traces its origin to avri fjtoiaxous, of which the French is contre les
moines.
I am unable to agree that the oils of the Pharmacopoeia furnish
examples of the immolation both of correctness and con¬
sistency. Oleum amygdalae is translated in the B.P. as almond
oil, because that is English, and not by the literal rendering “ oil
of almond,” which is not. There are two languages, English and
Latin, and it is poor scholarship to textually replace one by the
other. That is the sort of translation we 'get in a crib designed
exclusively to enable an ignorant student to pass an examination.
Oleum caryophylli and oleum cubebas are rendered oil of cloves
and oil of cubebs respectively ; the reason why they are in the
plural any more than oil of caraway or oil of coriander is because
English people seldom say oil of caraways and never oil of
corianders, while they invariably talk of cloves and cubebs. Some
years ago, wishing to be scrupulously correct, I printed a batch of
labels in the following style : Tincture of the Hop, because the
Latin was tinctura humuli ; Syrup of the Poppy, because the Latin
was syrupus papaveris. My father put the whole series in the
fire. It cannot be helped that myristicae adeps was a synonym for
oleum myrisfcicse expressum, because that was the case ; butyrum
myristicae never has been and could not, therefore, have been
inserted.
Neither can I agree as far as pharmacy is concerned, with the
adoption of the adjective when possible, instead of a noun in the
genitive to describe things. We sometimes call linimentum
camphorae, oleum camphoratum, just as the French say huile
camphree, because the preparation is olive oil impregnated with
camphor. We say oleum pliosphoratum because that is desiccated
almond oil in which phosphorus has been dissolved — non-pharma-
copceial oils may for the present be omitted. But we deliberately
say oleum amygdalae to show that it is the oil extracted from the
substance named.
The Paris Codex wishing to be accurate goes further still and
gives oleum ex amygdalis dulcibus ; oleum 6 seminibus ricini ;
oleum 6 seminibus crotonis. The genitive of the noun has been
universally accepted as bearing this signification.
The qualifying adjective is used for a distinct purpose ; the noun
in the genitive for another.
Let me now join hands respecting the word silvestris, which is
the classical spelling beyond doubt. Fluckiger and Hanbury so
328
PHARMACEUTICAL JOURNAL.
[Apbil 17, 1897
write the word, but Hanbury in his own materia medica papers
wrote always Pinus sylvestris, and so do most eminent botanists.
The question must be left to botanical authorities to decide.
I am glad to see that Mr. Coull entertains some idea of con¬
structing a prosodical table of official substances ; such an under¬
taking would be most useful ; its compilation would involve much
reference verification and, consequently, time. I speak from four¬
teen years’ daily experience when I say that even after the pro¬
duction of such a work our students will persist in imagining that
conium and camphora are the true methods of pronunciation.
ON CHICLE GUM.
BY EDWARD N. BUTT.
When at Campeche in Southern Mexico a few weeks ago, in
addition to logwood, mahogany, hides, and other miscellaneous
cargo, we shipped from thirty to thirty-five tons of chicle gum. At
Progresso, in Yucatan, our next port of call, another twenty-five
tons of chicle gum was added to the cargo. From subsequent
inquiries I found that the gum in question was produced by the
Achras sapota, a tree which grows wild in the forests in the State
of Yucatan and the immediately adjoining States of Central
America. It is indigenous from Mexico to Guaina, and cultivated
in all tropical countries.
Mode oe Production.
In the States of Campeche and Yucatan the Peons, as
the lower class of natives of Aztec descent are called, search
the forests where these trees grow, and having selected those
which are sufficiently mature, make Y-shaped incisions in
the stem. The juice which exudes from the incision soon
becomes indurated by exposure to the scorching heat of the
sun, and is subsequently collected. Fresh V-shaped incisions are
made in the same trees from time to time for a period of two or
three years, and the indurated gum collected. The trees are then
allowed to rest for four or five years, after which period they are again
fit to undergo the tapping process and yield fresh supplies of gum.
When a sufficient quantity of the crude gum has been collected
is pressed into thick oblong blocks, which weigh from twenty -five
to thirty kilos each. The collector then usually carries the gum
to the stores of the merchants, either suspended from his head or
packed on burros, as the Mexicans call that patient animal the
donkey. The exporting merchant usually packs three of these
blocks in a bale, the average weight of each bale being 80 kilos.
In the year 1895 no less than four million pounds weight of chicle
gum, of the estimated value of one and a-half million dollars
gold, was imported into New York from Mexico. I inquired
for what purposes this large quantity of gum was used, and found
it was the basis or chief ingredient used in the manufacture of
“ chewing gum,” a substance practically unknown in this country)
but almost universally used in the United States by men, women,
and the young of both sexes — many of the male population having
adopted it as a harmless substitute for tobacco. The habit
of chewing “ chewing gum ” is said not only to increase the flow
of saliva but to relieve indigestion and dyspepsia. This may
possibly be the case with those samples which contain pepsin,
especially as the once prevalent habit of spitting is rapidly on the
decline, partly due to the substitution of gum for tobacco for
chewing purposes, but mainly in consequence of the affixing of
notices in all the street cars of most of the cities in the Eastern
States prohibiting spitting therein — signed “By order of the
Board of Health.”
On American Chewing Gum.
When. I had obtained the above information respecting chicle
gum, I determined to make further inquiries and obtain as much
information as I could about the manufacture of “ chewing gum”
during the short time I was in New York.
Historical.
A quarter of a century ago there were practically only two kinds
of “ chewing gum ” in use in the United States, viz., the regularly
prepared spruce gum, and shoemaker’s wax. A little later a
mixture of paraffin wax with either resin, balsam of tolu, or some
other ingredient of a similar character was put on the market.
This new variety of chewing gum rapidly became a favourite with
the ladies and also with the youngsters, who called it “Coal-oil
gum.” Preparations called “Taffy tolu” and “ Snapping wax,”
were next introduced for similar use. These preparations acted a
the pioneers for the enormous trade which has sprung up i
“ chicle chewing gum.” Its present use was discovered by an
accident. Some twelve or fourteen years ago a lot of this Mexican
gum was sent to New York on board ship partly as ballast,
and partly in the hope that it would be found suitable for use by
bookbinders or possibly in the leather trade ; after several trials it
was’ found to be quite useless for any known purpose, and failing
to find a purchaser, it was decided to tow it out to sea and throw
it overboard in order to get rid of it. Just at that time one
man out of the hundreds who were standing on the wharf casually
picked up a piece of the gum, examined it, and found it would
“chew.” The idea at once occurred to him that it would forma
suitable basis for making a new kind of chewing gum, and without
difficulty he succeeded in obtaining the whole lot for the trouble of
shovelling it out of the ship. That man was a Mr. Adams, the head
of the firm of Messrs. Adams, Sons and Co., of 148 to 155, Sands
Street, Brooklyn, New York, whose manufactory I visited, and to
whom I am indebted for the sample of chicle gum, which is now
in the Museum of the Society, also for much of my information.
Messrs. Adams, Sons, and Co. also gave me a box of chewing gum
as prepared for use. It is called Pepsin Tutti-F rutti chewing gum.
It is flavoured with oil of peppermint, and each tablet is said to
contain one grain of Armour’s high test pepsin, guaranteed to digest
2500 grains of meat. This firm prepare many other varieties of
“gum,” and it is quite evident they do an enormous business,
as they have a very large factory, which is provided with
every labour-saving appliance it is possible to introduce, and
yet I understand they find work for 350 to 400 employes in the
winter season, and about 450 in the summer season, from 250 to
300 of these employes being young women. The firm of which Mr.
Adams is the head is not only the largest importer of the crude
gum, but also the largest manufacturer of chewing gum in the
United States, whilst Mr. Adams himself is reputed to be a
millionaire several times over.
Manufacture of Chewing Gum.
Mr. Adams’ first venture in making chewing gum was cooked in
a tea kettle and worked up on the kitchen table. Now, the gum
as taken from the bales is first chopped into small pieces and then
boiled in water. Wood, pieces of bark, and all other impurities
which are light, separate from the gum, float on the surface, and
are skimmed off, whilst those which are heavy, such as dirt,
stones, etc. , fall to the bottom. When the gum is perfectly clean
and all the foreign substances have been got rid off, it is removed
to a mill, where it is ground up, the mill making about 3500
revolutions a minute. The ground gum is then subjected to a
continuous heat of 140° F. in drying rooms. When the gum is
sufficiently dry it is sent to the cooks, who put it into large
steam jacketed pans and add to it pure white sugar, granu¬
lated pepsin, powdered kola, or other desired ingredients.
It is then turned and mixed by an ingenious double-
April 17, 1897]
PHARMACEUTICAL JOURNAL.
329
acting rotating paddle until it has assumed the consistency of
bread dough. The “doughboys” then take it in hand and add
to it the flavouring ingredients, such as oil of peppermint, oil of
wintergreen, etc., etc., and whilst still warm thoroughly work and
knead it until it looks like gingerbread, finely powdered sugar
being added from time to time during the kneading process to
prevent its sticking. It is then allowed to cool, and afterwards
passed through steel rollers until reduced to the proper thickness,
when it is removed to the markers, steel-knived rollers which
partly cut through the long sheets of gum. Next it is removed to
the seasoning room, and finally broken up into pieces of suitable size
on the lines left by the markers. The finished gum then goes to
the wrapping room, where the nimble fingers of 150 to 200 young
ladies wrap it in waxed paper, tin foil, and pretty wrappers, and
these to the packers, who pack it in jars or boxes, ready for sale to
the numerous dealers.
Recipes for Making Chewing Gum.
Should any one in this country be desirous of embarking in the
manufacture of this article I append a few formuhe which I have
taken from Merck's Market Report, but the different varieties and
various flavours now on the market may be numbered by hundreds.
Those varieties, however, of which chicle gum is the basis, are those
which are most in favour at the present time in the United States.
1. — Balsam Tolu . 4 parts
Benzoin . 1 part
White Wax . 1 part
Paraffin . 1 part
Powdered Sugar . 1 part
Melt together, mix well, and roll into sticks of the usual dimensions.
2. — Balsam Tolu . 4 parts
Resin White . . . „ . 10 parts
Paraffin . . . 3 parts
Powdered Sugar . . . Sufficient
Melt the balsam, resin, and paraffin together, and while still fluid incorporate
sufficient sugar to make a suitable mass. Roll out with powdered sugar, and cut
into pieces.
3. — Balsam Tolu . . . 3 parts
Powdered Sugar . 1 part
Oatmeal . 3 parts
Soften the gum on a water bath, and mix the ingredients ; then roll in pow¬
dered sugar, and cut into sticks.
4. — Venice Turpentine . . . . . . 40 parts
Common Turpentine . 30 parts
Yellow Wax . 20 parts
Balsam Tolu . 4 parts
Balsam Peru . 2 parts
Melt together and add in fine powder.
Cinnamon . . 12 parts
Chocolate . 20 parts
Red Sandalwood . 4 parts
Sugar . 2 parts
Myrrh . 2 parts
Galangal . 2 parts
Ginger . 2 parts
Cardamom . ! . 1 part
Mix, and when sufficiently cool, roll out into sticks or any other desirable form.
5. — Gum Chicle .
Paraffin Wax
Balsam Tolu
Balsam Peru
3J lb.
1 lb.
2 ozs.
1 oz.
Dissolve the gum in as much hot water as it will take up, melt the paraffin, and
mix all together, then take —
Sugar . .
Glucose
Water. .
10 lbs.
4 lbs.
3 pints.
Dissolve the sugar and glucose in the water, boil the solution up to the “ crack ”
degree, pour the syrup upon an oil slab, turn into it sufficient of the above gum
mixture to make it tough and plastic, incorporate the flavour (powdered cinna¬
mon, chocolate, sandalwood, myrrh, ginger, or cardamom), and, when sufficiently
cool, roll into sheets or sticks.
As there is “so much money” in chewing gum, some one may
be desirous of going into the trade, but before starting to manu¬
facture he must make sure of a continuous supply of the raw
material. At the present time the whole of the export trade
in gum from Mexico is in the hands of a very few persons, and the
importers and manufacturers in the United States are also very
few in number, less than half a dozen I believe, who not only hold
contracts with the exporters, but also refuse to sell the raw
material. It is also a country in which “ rings ” are not unknown.
THE ANALYSIS OF FATTY OILS.*
BY R. C. COWLEY.
The matter dealt with in this paper is one that cannot be satis¬
factorily discussed in one lecture, but is rather one which, from its
extent, should be divided into a series covering a space of time at
least equal to that allotted to our winter session. I propose to
deal with commercial analysis of fats— an important matter to
soap boilers, candle makers, and in pharmacy — in as concise a way
as possible, principally from a pharmacist’s point of view. As a
rule, analysis of the kind I intend to describe is not followed out in
its entirety by pharmacists, who generally confine their examina¬
tion of oils and fats to organoleptic methods, such as observing the
colour, taste, odour, and density of the specimens. These methods,
however commonplace they may appear, must not be overlooked,
for in applying them the average pharmacist can, as a rule, give
points to the analytical chemist, and moreover his opinion is
generally to be relied on. However, in order to thoroughly protect
the retailer against adulteration and sophistication, chemical and
physical tests must be resorted to, necessitating a thorough training
in analysis.
Fats are ethereal compounds of glycerol, generally as oleates,
stearates and palmitates, with small admixtures of other com¬
pounds, these latter being particularly characteristic of the
individual fat, for instance, butyric acid in butter, and arachidic
acid in ground nut oil.
Waxes are compounds of the alcohols of the methyl series, so
that according to this definition a wax is not necessarily a solid
body.
A number of different classes of acids and alcolols maybe present
in fats, wax, etc. , corresponding to the various classes of saturated
and unsaturated hydrocarbous. Those fats containing the most
saturated fatty acids are non-drying, and those containing the less
saturated fatty acids are drying : their drying properties in¬
creasing with the degree of unsaturation. Thus we have in linseed
oil, containing unsaturated linoleic and linolenic esters of glycerol,
an extreme type of drying oil whose residue on drying is an
amorphous varnish. When heated the density of fats diminishes,
eventually they are decomposed, the products of destructive
distillation being a number of hydrocarbons — a fact which favours
Engler’s theory that petroleum has been formed by the decom¬
position of the bodies of fossil marine animals.
Perfectly pure fats are described as being colourless, odourless,
and tasteless, the substances giving the particular colour, odour,
and taste to fats being foreign matter. On exposure to sunlight
the colouring matter is bleached, hence the custom of bleaching
castor oil. The natural glycerides are neutral substances, but
become acid after separation. On exposure to air and light fats
become rancid. This does not appear to be due to the liberation
of fatty acids. Micro-organisms have been credited with causing
this rancidity, a theory supported by the discoveiy of bacteria in
poppy-seed oil, but Ritsert has shown that pure lard is nob
turned rancid by bacteria, but as a matter of fact it kills them.
Enzymes, again, do not turn fats rancid, nor does moisture, so that
these changes may be put down to oxidation, intensified by light
causing the fatty acids to split up into acids of lower molecular
weight.
Solid fats, especially those of animal origin, do not rancify so
readily as liquid fats. They seem to resist the action of light better.
On exposure to air fats absorb oxygen, increasing in weight up to a
certain point, at the same time the proportion of carbon and hydrogen
in them diminishes, and they become viscous. “ Blown oils” are
made by passing a current of air through them to increase their
viscosity. Fats are soluble in water in minute traces. They are only
dissolved in cold alcohol in small quantity, except castor oil,
croton oil, and olive kernel oil. Pharmacists and perfumers
frequently make use of the solubility of castor oil in alcohol in
preparing brilliantine and hair washes. Ether, chloroform, carbon
disulphide, benzene, petroleum ether, and petroleum all dissolve
fixed oils except castor oil, which is not soluble in petroleum oil,
heavy or light. Pure stearin is not very soluble in ether, but its
* Read before the Liverpool Pharmaceutical Students’ Society.
330
PHARMACEUTICAL JOURNAL.
[April 17, 1897
solubility is increased by the presence of other fats. Sulphur and
phosphorus are dissolved in small quantity by oils, which fact is
made use of in the Pharmacopceia in making two official plasters
and phosphorated oil.
Sulphuric acid attacks fats, evolving S02 and causing consider¬
able rise in temperature ; this is Maumene’s test. Nitric acid
reacts violently with fats, forming hydroxyl compounds. Nitrous
acid converts the triolein, etc., in non-drying oils into trielaidin,
trierucin, etc., their solid isomeride causing them to become
thicker. Drying oils with nitrous acid remain liquid. This test
is of great utility in detecting cottonseed oil in olive oil and lard.
Chlorine and bromine with saturated oils form substitution pro¬
ducts, evolving at the same time HC1 and HBr ; with unsaturated
oils they form addition compounds as well. Iodine does not form
substitution products, but is slowly absorbed forming addition
compounds. Saponification or hydrolysis of fats and oils takes
place when they are acted upon by alkalies, acids, or superheated
steam, the stearins and palmitins being more easily split up than
oleins.
In analysis this hydrolysis is effected by means of strong caustic
alkalies in alcoholic solution, but many waxes can only be saponi¬
fied by using solution of sodium ethoxide ; this is the case
notably with wool fat. Sometimes saponification is brought about
under pressure.
The physical properties of fatty oils are, as I before remarked,
of considerable importance, and are briefly summed up under the
heads viscosity, microscopic appearance, specific gravity, melting
point and solidifying point. The last three I shall describe some¬
what in detail.
Specific Gravity should be taken at a constant temperature,
preferably 15 ’5 C. It may be determined by a pyncnometer, a
specific gravity bottle or a hydrostatic balance, the first two giving
the best results. For solid fats or waxes, Hager’s method is very
useful. It is performed by dropping the melted substance into a
mixture of alcohol and water from a height of about a quarter of
an inch above the surface, so as to form well-rounded drops. These
drops are freed from air bubbles, dropped into spirit, water is
added until they begin to float in the liquid, upon which the gravity
•of the liquid is taken, which represents that of the wax.
Melting ' and Solidifying Points. — There are various methods for
determining these, leading to many and discordant results, which
will be readily understood if one considers the composition of fats.
Again, the temperature, which should be regarded as the true
in el ting point, is uncertain ; some workers take the point of
incipient fusion, and others take that of complete fusion as the true
melting point. The best course is to state both. The most
common methods employed are as follow : —
Pohl’s. — The bulb of a thermometer is dipped into melted fat
so as to become well coated. It is then enclosed in a test tube by
means of a perforated cork, and held over a hot iron plate ; as
soon as a drop of liquid fat is seen on the thermometer bulb, the
temperature is noted.
Redwood’s modification of the above is to be recommended on
the score of , simplicity. The fat is placed on the surface of
mercury contained in a dish heated over water. The temperature
at which the fat spreads over the mercury is taken as the melting
point.
The Pharmacopoeial Method of filling a capillary tube with the
fat, and attaching it to a thermometer, and warming it in a suit¬
able liquid, is useful, but it is best to fill the tubes at least twenty-
four hours before taking the melting point, so that the fat may
assume its normal condition, which is changed to a slight extent
by heating.
As the melting point of fats is somewhat uncertain, and this
uncertainty is intensified by the presence of fatty acids, the solidi¬
fying point of the separated fatty acids is often determined by
what is known as the “ Titer test,” which depends on the fact that
when a substance is melted and allowed to cool a point is reached
when the temperature rises suddenly a few fractions of a degree
before it falls again. The maximum point reached is called the
* ‘ titer ” or solidifying point.
Under the head “Quantitative Reactions” I will briefly describe
the methods used for obtaining what are known as the chemical
constants of fats, etc. They are enumerated as follow : — -
1. The acid value.
2. The saponification value.
3. The ether value.
4. The Hehner value.
5. The Reichert-Meissl value.
6. The iodine value.
7. The acetyl value.
1. The Acid Value is the number of milligrammes of KOH
required to saturate the free fatty acids in 1 gramme of a fat. It
is ascertained by dissolving a weighed quantity of a fat in alcohol
and titrating with penta or decinormal alcoholic potash, using
phenolphthalein as an indicator. Some 10 grammes of fat is a
useful quantity to work upon.
2. The Saponification Value is the number of milligrammes of KOH
required to entirely saponify 1 gramme of a fat. It is obtained by
boiling 2 grammes of fat with 25 C. c. of semi-normal alcoholic KOH
(standardised against HC1) for half an hour, and titrating back with
the HC1 solution, using phenolphthalein as an indicator.
3. The Ether Value is readily seen to be the difference between
the acid and saponification numbers.
4. The Hehner Value indicates the proportion of insoluble fatty
acids in a fat, and is determined by saponifying 3 or 4 grammes of
fat with strong alcoholic potash, boiling down to a paste, dissolving
in water, decomposing with an acid, heating until the fatty acids
rise to the top of the liquid, filtering through a weighed filter
paper, washing with boiling water until the washings are no longer
acid. The funnel and contents are now cooled in cold water, and
the fatty acids allowed to solidify on the surface. These acids are,
after carefully drying at 100° C. for two hours, weighed, and the
percentage calculated. As oxygen is absorbed by the acids on
drying, a constant weight will not be obtained, so that the lowest
weight reached will be the correct one.
5. The Reichert-Meissl Value is the number of C.cs. of decinormal
KOH solution required to neutralise the volatile fatty acids from
5 grammes of fat. Meissl’s process is to take 5 grammes of
melted fat, saponify it with KOH in alcoholic solution in a 200 C.c.
flask, and evaporate off the alcohol. Then add 40 C.cs. of 1 in 10
H2S04 to 'liberate the fatty acids, which are carefully distilled,
using a suitable condenser, until 110 C.cs. have passed over.
Filter 100 C.cs. of this distillate into a flask, and titrate with deci¬
normal KOH. The number of C.cs. of solution used are increased
by one-tenth, this gives the Reichert-Meissl value.
6. The Iodine Value is the percentage of iodine absorbed by a
fat. It is usually arrived at by Hiibl’s process, for which the
following solutions are necessary : — •
1. Solution of 30 grammes of IIgCl2 in 500 C.cs. alcohol mixed
with an alcoholic solution of iodine (25 grammes in 500 C.cs.).
2. Solution of sodium thiosulphate standardised against iodine.
3. Pure chloroform.
4. Solution of potassium iodide.
5. Starch paste.
About T3 gramme of a drying oil or '3 to '4 of a non-drying oil
is dissolved in chloroform, and 25 C.c. of iodine solution run in and
allowed to stand in a dark place for two hours. If the colour is
discharged a similar quantity is again added and allowed to stand
another two hours. Some of the KI solution is now added and the
solution diluted with 300 to 500 C.c. of water. A precipitate of
Hgl2 indicates an insufficiency of KI solution, which must be
added until the precipitate redissolves. The excess of iodine is
now determined by the thiosulphate solution, and the amount of
iodine in the Hiibl’s solution also determined by a blank test ; from
this the percentage of ‘iodine absorbed by the fat is calculated.
Hubl’s method is of great use in determining the presence of
drying oils in non-drying oils, as for instance cottonseed oil in
olive oil.
7. The Acetyl Value furnishes a measure of the proportion of
hydroxy acids or higher alcohols in a fat, and depends on the fact
that when any hydroxy acid or alcohol is heated with acetic anhy¬
dride, acetic esters are formed. The separated fatty acids are
heated with acetic anhydride in a flask with a reflux condenser for
two hours, and the acetyl value is arrived at by an equivalent
method to that employed in determining the ester or ether value.
Maumenes Test may almost be regarded as a quantitative test,
and is very useful for distinguishing drying from non-drying oils.
The rise in temperature when H2S04 acts on a drying oil is higher
than when a non-drying oil is used. It is measured by means of a
delicate thermometer.
Qualitative Reactions are made use of in the examination of
individual oils for adulteration. They usually take the form of
colour tests. Reagents such as the sulphuric acid, chromic acid,
nitric and sulphuric, phosphoric acid, etc., are used.
Baudouin’s Test for sesame oil in olive or almond oils is of the
greatest use to pharmacists, and is performed by shaking the
APRIL 17, 1897]
PHARMACEUTICAL JOURNAL.
331
sample with solution of sugar and hydrochloric acid, when if
sesame oil be present a crimson colour develops on standing.
Beech? s Test. — This is advised by the Italian Government for
showing the adulteration of olive oil with cottonseed oil, and
requires two solutions
No. 1 solution consisting of—
Silver Nitrate .
Alcohol, 98 per cent.
Ether .
Nitric Acid .
No. 2 solution is—
Colza Oil . 15 c.c.
Amyl Nitrate . 100 C.c.
Use as follows : — Take 10 C.c. of the oil and mix with 1 C.c. No. 1 solution
and 10 C.c. No. 2 solution. Shake together and divide into two equal parts
in separate test tubes, one of which must be placed in boiling water for
fifteen minutes and then compared with the other. If cottonseed oil is
present, the oil in the heated tube will become reddish brown.
Nitric Acid, Test for cottonseed oil in olive oil. Shake the
oil with nitric acid, sp. gr. 1 -37, when a characteristic coffee-brown
colour will be produced if there is adulterati .n even to the extent
of 2 or 3 per cent.
In the systematic examination of fatty oils the following deter¬
minations are important : —
1. Specific gravity.
2. Melting and solidifying points.
3. Melting and solidifying points of the fatty acids.
4. Behaviour with solvents.
5. Hehner value.
6. Reichert-Meissl value.
7. Saponification value.
8. Iodine value.
l'OO gramme.
200-00 C.c.
40-00 C.c.
•1 gramme.
Taking olive oil and cottonseed oil as examples, we have the
following physical and chemical constants : —
Olive Oil.
Specific gravity . j-
Solidifying point of fatty
acids
Hehner value .
Reichert-Meissl value
Saponification value . .
Iodine value .
Maumen^’s test .
....[
:.
Cottonseed Oil.
0-914-0-917 at 15° C.
•922--930
(Allen)
(Allen)
21°-22° C.
32° C.
(Allen)
94-96 95-43
95-87
(Lengf eld) (West Knight)
"3
(Bensemann)
191-196
191-196-5
(Allen)
(Allen)
82-8
106
(Hiibl)
(Hiibl)
41-5-45-5 C.
75-76° C.
(Archbutt)
(Archbutt)
In these cases it will be seen that the iodine value, Maumene’s
test and the solidifying point of the fatty acids show the greatest
difference, as one would expect from the character of the oils, olive
oil being a non-drying oil, and cottonseed a semi-drying oil. The
addition of cottonseed oil to olive oil would raise the factors in all
cases.
PROGRESS IN PHARMACY *
BY GEORGE SINCLAIR.
If one Were asked to describe in one or two words the outstand¬
ing characteristics of the time in which we live, probably no
better description could be given than to say that it was an “ Era
of Progress.” In every sphere of activity and in all departments
of life the nineteenth century, and especially the latter part of it,
with which we are naturally more intimately acquainted, has wit¬
nessed remarkable development and progress.
In the region of science, probably more than any other, has this
progress been most pronounced and most brilliant, and within
that great region the two departments with which our profession
or craft has intimate, if not inseparable connection, namely,
chemistry and medicine, have made great advances and important
discoveries ; but ours is not only a profession, it is also a trade,
and, therefore, social progress affects us, and in this connection
also advance and development have been made, and we have found
ourselves — whether we are willing or not — compelled to move
with the times, and keep step with the great army of progress.
My subject then, “ Progress in Pharmacy ” (I may mention it
was not quite my own choice) will, I daresay, seem to you a very
high-sounding and ambitious title — quite out of the keeping with
the nature of the few remarks that follow.
* Read before the Edinburgh Chemists’ Association,
There are many lines along which the subject might
be studied with profit and with interest. One might
speak of the progress that has been made in raising the
standard of pharmaceutical education, and in this connection it
might be profitable, although probably not pleasant to
look at the results of this demand for greater knowledge, viz., the
steadily increasing number of failures at our exams. It almost
appears that here we are progressing backwards ; or we might
consider the very evident progress that has been going forward in
the way of giving to the pharmacist a higher social professional
standing, a position which, by his special training and education
he is quite entitled to, and in spite of hostility in the public press
and even in the courts of justice, this is being accorded to him by
the public.
Or again we might consider the progress and changes that have
taken place in therapeutics entailing similar changes in pharmacy.
But the subject is so large and so comprehensive that to treat it
adequately within the limits of a short paper such as this, is
obviously impossible, and even if it was possible I am so obviously
incapable of doing justice to it that I will not attempt it, but
propose, with your permission, to confine my few remarks to only
one phase of the progress which has been going on in pharmacy
for the past few years, viz. , to what I have called the development
of refined or elegant pharmacy. As a natural result of the increase
of wealth and the much greater distribution of wealth, which has
been such a characteristic feature of the present generation, there
has been an enormous increase of what one might call ‘ ‘ artistic
taste,” a love of elegance and refinement to which our forefathers
were altogether unaccustomed. Mankind in general — not of course
including chemist’s assistants and apprentices — have no desire
nowadays to “ scorn delights and live laborious days.”
In a recent article on ‘ ‘ Comfort and its Possible Effects ” in
the British Medical Journal, the writer, speaking of this tendency,
says “Nowadays the eye must be regaled with aesthetic de¬
corations, with elegant corners and dados, stained glass, fine
pictures, handsome furniture, no harsh sounds must grate upon
the ear, an agreeable and equable temperature must be maintained
throughout.” Luxurious lounging chairs and couches must be
provided in every room, the bedrooms must be warmed in winter,
hot and cold water must be laid on to every landing ; ‘ ‘ the cooking
must be such as to stimulate a jaded appetite, and communication
must be easy between all parts of the house by means of electric
bells, speaking-tubes, or telephones.” “ When away from home
locomotion must be made as agreeable and as little fatiguing as
possible. Even sport, such as cricket, and shooting, and hunting,
must be carried on comfortably, with proper arrangements for a
nutritious luncheon and five o’clock tea.” Then the writer goes on
to point out the danger of all this, and to sound a note of warning.
I do not personally agree with all he says ; it almost seems as if
he had been taking notes at a performance of “ Utopia, Limited,”
but there is a great deal of truth in it.
Now, gentlemen, this may seem to you to have little or no con¬
nection with the present subject, but I think it is just here that
we may find the real cause and origin of the ‘ ‘ elegant pharmacy
cult.” People who live in this atmosphere of pampered and
luxurious ease (and they are just the people on whom the pharma¬
cist chiefly depends for his business), and whose greatest aversion
is to have to do anything unpleasant or to put themselves to any
inconvenience, would go into hysterics if asked to take a dose of
castor oil ; as a matter of fact (except for babies who have not the
sense to refuse it) their doctor would never think of prescribing
anythihg so heroic for them. If he did, it would be in capsules or
palatable aperient or some such form. How this has affected phar¬
macy can be made quite clear by citing a few examples.
A very good example of the evolution of an elegant pharma¬
ceutical product is cod-liver oil. First we have the rich brown oil
of Dr. de Jongh, which the rhyme says is so good and so strong ;
then we have pure bleached, tasteless oil that gives place to an
emulsion, which the maker, but no one else, says is as “ palatable
as cream”; further on still we have morrhuse done up in sweet
little morsels of capsules, without the slightest suspicion of oil
about them ; and finally for still more fastidious palates, we cater
with a nice wine of cod-liver oil which contains all the active
principles of pure oil.
Cascara sagrada is another example. Probably the best form of
this valuable laxative is the fluid extract, but then it is bitter, and
that is fatal, so we proceed to debitterise it, and get aromatic fluid
extracts and cordials ; then we have it in capsules, tabloids,
palatinoids etc., etc. ; it is even put up in the form of a
332
PHARMACEUTICAL journal.
[ApbIl 17, 1897
delightful jelly for children, which latter sometimes make us
wonder if, after all, the apple jelly which for all sorts and condi¬
tions of drugs— which we were accustomed to when young — had
nothing to recommend it.
I may seem to exaggerate when I say that nowadays a drug or
medicine, to have any chance of being widely used, must be fairly
palatable and easily administered, for it seems to be a most
important consideration with a doctor, in this easily administered
nauseous medicine seem to haunt his and his patient’s dreams.
What, for instance, prevents paraldehyde from being much more
widely used than it is, seeing it is undoubtedly one of the best and
safest hypnotics we have ? Its persistent unpleasant odour and
nauseous flavour, and nothing else.
I take it, then, that the main factor in producing a demand for
elegance in pharmacy have been the growth of a luxurious style of
living and of cultured tastes, with a consequently natural evulsion
at the unnecessarily crude and nauseous nature of the good old-
fashioned remedies.
Considering the matter from our present standpoint and at this
far-advanced date, it is quite easy for us to understand how natural
and how much to be expected it was that such a change should
come. Unfortunately, however, dispensing pharmacists’ eyes were
holden that they could not see, their ears were hardened that they
could not hear, and they failed to discern the signs of the times,
or they would have bent all their energies to adapt themselves and
their methods to the new demands made upon them. As it was
they looked askance at any attempt to make medicine pleasant ; it
was heresy, medicine always had been nasty and always ought to
be, and if it was made pleasant, ten chances to one it was no good,
all of which may or may not have been true; but it certainly did not
pay, and as was to be expected, this conservatism carried its own
retribution with it, and retail pharmacists are only now beginning to
realise how much they have lost by allowing the elegant move¬
ment to be carried on in the first instance by the large manufac¬
turing firms, the result being, as we all know, that the shelves of
our pharmacies to-day are filled with such products of elegant
pharmacy as bi-palatinoids, capsules, gelatin-coated pills, elixirs,
liquors, jelloids, jellies, tabloids, tabellse, palatinoids, and that
questionable form of elegant pharmacy, medicated wines, the
popularity of which I am much inclined to think depends not so
much on their being elegant medicines as elegant tipples. I do
not, of course, speak of the all as such.
One has only got to compare a few pages of a prescription book
of the present date with one say ten years ago to find out the
great increase in the use of the above products. I had the
curiosity to do this, and found that ten years ago an average of
5 per cent, of recipes were for products of large manufacturing
firms ; to-day the average has reached 20 per cent. , an increase of
15 per cent, in ten years. If the increase goes on at this ratio,
we will soon be mere automatic machines for scraping off makers’
labels and writing and putting on our own.
I believe, indeed, that this matter is becoming a very serious
one for the retail pharmacist. On the one hand, his business has
been curtailed by the cutter, so far as patent medicines are con¬
cerned, and on the other hand, that department, which we in
Scotland at least still believe — in spite of what the Chemist and
Druggist says to the contrary — to be the mainstay of our business.
I mean the dispensing department — is being undermined
by the number of these elegant products, which are kept
continually before doctors by means of liberal supplies of
samples, etc., and which so frequently bear a very small
margin of profit ; taking into consideration the stock that
has to be kept, and the loss arising from having a bottle
left two-thirds full on his hands. Not only so, but his reputation is
being damaged by statements such as the following: — “Pills
superseded,” “The failure of shop tinctures,” etc., etc., which are
kept persistently before the medical profession by means of ad¬
vertisements in their journals.
It behoves us, therefore, as members of this Association, and as
those who hope one day to have pharmacies of our own, to make
up our minds as to how we are going to stand in regard to this
tendency. The time has long gone past for ignoring it, and it
seems to me that what we have to do is for each of us to determine
that up to the best of our ability we will be “elegant pharmacists.”
I have not any startling or novel theories to propound as to how
we are to become so, nor do I think that such are needed. I believe
very strongly that, within well-defined limits, the retail dispensing
pharmacist can, if he chooses, turn out from his dispensing counter
products which will compare favourably in point of accuracy of
dosage, elegance, and activity, with the products of any large manu¬
facturing firm. But the reason the products of such firms have
got such a hold, and have almost, as they themselves claim, revo¬
lutionised prescribing, has simply been that in the past we have
not paid sufficient attention to these details, and the sting of the
accusations which are brought against us lies in the modicum of
truth which they contain,
Take for instance pills which tabloids, palatinoids, etc., are
supposed to have or are destined to supersede. Only a few v eeks
ago an eminent doctor, one of the professors in the College of
Medicine here, came into the phai'macy where I am employed
wishing to prescribe a particular pill of a well-known American
house, of which the full formula was given. Not
having the pill in stock, I suggested that we could
easily make the pills for him — equal in all respects to the
American article, and I was met by the somewhat crushing reply,
that 1 ‘ If there was one thing Edinburgh chemists could not do,
it was to turn out decent pills — they were either sent out smothered
with powder, or all adhering to each other.” I was able to over¬
come the doctor’s prejudice, and I think he is modifying his
opinion. The points which are urged against pills (Helbing and
Passmore) are inaccuracy of dosage, insolubility and unpalata-
bility. All these three can be overcome and ought to be over¬
come by every careful dispenser, but (although I fear I will be
censured by saying it) they are not always so. In regard to the
first for instance, some fellows seem to think that for even the
most powerful ingredients, four or five rubs with the pestle
ensures accurate intermixture and sub-division. I speak of what I
have seen. I have noticed a dispenser put one grain of arsenic
into about 240 grains of mixed powders, and after giving it five
or six turns with the pestle proceed to mass the pills. How under
such conditions he expected to get sixty pills each containing 60th
of a grain of arsenic, I do not know — he evidently relied on the
massing to do the rest of the mixing, but this, for powder
ingredients, especially powerful ones, is a fatal mixture. Insolu¬
bility is also urged against pills, but this objection except in
the case of pills which have lain too long in stock and have
consequently become hard and dry, is not upheld by experience,
and furthermore the objection is based largely on experiments
carried on outside the body by means of watery solutions or
acidified watery solutions, and I think it is pretty generally admitted
that such experiments do not at all correspond to what goes on inside
the body. The third objection, and one of which much has been
made, is the superiority of the tabloid, etc. , over the pill as regards its
palatabilityand appearance. This I fear we must admit is or at least
has been true, but there is not the slightest reason why it should
remain so. Even in the limited time at our disposal at the dis¬
pensing counter, pills can be turned out, varnished, or pearl-
coated, to look and to taste every bit as well as tabloids or sugar-
coated, or any of the much advertised gelatin-coated pills. If
pills are made before the prescription is copied, and varnished with
a juniper gum and alcohol varnish, by the time the prescription is
copied and labels written they will be found to be quite dry and
to have a brilliant polished appearance. I see no reason, there¬
fore, why the old and venerable practice of rounding pills with
chalk just as they come off the machine, and shaking some loose
powder in the box with them, should be continued. The pills do
not look elegant, and they are very frequently anything but
palatable.
But there are a large number of drugs, some of which are in¬
soluble and some nauseous, that are not at all suited for pill¬
making, such asphenacetin, antipyrine, bismuth, rhubarb and soda.
The bromides, sulphonal, and a host of others, for such the cachet
forms a mode of administration, which to my mind is perfect. It
is elegant, easily prepared, easily swallowed, and almost
instantaneously soluble. If, however, we wish to bring the cachet
into popularity, then precautions must be used in filling them.
1. The proportion of the drug for each cachet ought to be
separately weighed. 2. Closing must be securely and accurately
done. 3. No adherent powders must be left about the edges of
the cachet, otherwise its palatibility is marred.
I hope you will pardon me if I seem to be taking up your time
with rudimentary and uninteresting details. I do so simply
because I am firmly convinced that it has been a want of strict
attention to these details that has been at the bottom of
a good deal of the mischief. Although I have classed capsules
amongst the products of the large manufacturing firms,
they are one of those things which can On a small scale be manipu¬
lated quite well at the dispensing counter. Powders can be filled
ArRiL 17, 1897J
PHARMACEUTICAL JOURNAL.
333
dry by means of a small funnel, or made into a semi-liquid mass
with vaselin and filled through a syringe with an elongated nozzle:
Liquids such as terebene, turpentine, guaiacol, paraldehyde,
eucalyptus oil, etc., can be filled by means of a glass pipette
(sample shown). Then every pharmacist, especially members of
this Association (who have been benefited by a practical demon¬
stration), ought, when occasion demands, be able to turn out
elegant effervescent granules. He has also to be a bit of a con¬
fectioner and able to turn out pastilles on an hour or two’s notice,
but I need not go on multiplying examples of elegant pharmacy,
as you are doubtless all well acquainted with and able to tackle
them all. My aim in these few remarks to-night has not been to
suggest new ideas or new methods as to try and impress on you
and on myself the necessity of developing and perfecting the
methods and ideas we already possess.
That we may be able to do this successfully three things, I
think, are essential, viz., elegance, accuracy, and resource. If we
keep these three always before us and' put them into practice, we
shall worthily uphold the dignity of our craft, and perchance to
help it forward one step in the onward path of progress, and so
hasten the coming of that better day which is said to be dawning
somewhere for pharmacists.
REVIEWS AND NOTICES OF BOOKS.
A Manual of Chemistry, Theoretical and Practical, based on
Watts’ edition of Fownes’ Manual. By William A. Tilden,
D.Sc., F.R.S., Professor of Chemistry in the Royal College of
Science, London, Examiner in Chemistry to the Department
of Science and Art. Pp. 599. 10s. London : J. and A.
Churchill. 1897.
Watts’ ‘Manual of Chemistry,’ based on Fownes’, the last
edition of which was revised by Professor Tilden, is so universally
accepted as the best manual of its kind that a new edition is sure
to be welcomed by all students of chemistry. In this edition it
has been necessary “to re-write a large part of the existing
matter, and to add a considerable amount of new,” so that “ the
last traces of the work of Fownes have disappeared in the process,
hence, although the general arrangement of the contents is similar
to that of the original, we have now a practically new book, in
which the phraseology as well as the matter has been modernised.”
It was hardly necessary to add “ that this book is not intended for
children,” but it correctly defines its aims in “presenting in a
compact form a body of facts and a statement of the leading
doctrines of modern chemistry suitable to the needs of students
who are receiving instruction under a teacher and who require a
manual to which they can resort for the purpose of verifying and
extending such information as they receive in the lecture room.”
In this volume, which deals with inorganic chemistry, we
have in an introduction of twenty pages a very clearly- written
account of the most important events in the development of
chemistry from Boyle onwards, and of the growth of the
principles of the atomic theory of Dalton until completed and
consolidated by Berzelius. The order of study in this
edition follows an arrangement of groups in which the
members independent of valency are in obvious natural
relationship rather than in adherence to the periodic system of
classification. Thus commencing with hydrogen and the proper¬
ties and diffusion of gases, we are led on successively to oxygen,
nitrogen, atmospheric air, the analysis of air and the methods for
the determination of the relative densities and for the liquefaction
of gases ; then to combustion, the oxides of hydrogen, solution of
solids, and the properties of solutions, before dealing with the
halogens, the sulphur group, .and the nitrogen compounds. Then
follow the phosphorus group (P, As, Sb) — carbon, silicon and
boron, ozone, and hydrogen dioxide. This comprises what may be
regarded as the first part. Theoretical chemistry is then fully
considered before treating of the metals.
That in all the subjects dealt with Professor Tilden has included
the latest researches it is only necessary to refer to the articles on
the liquefaction of gases, where we find Pictet and Cailletet’s,
Olszewski and Hampson’s methods and apparatus described and
illustrated ; also to the one on combustion to see the latest form of
Clowes’ safety lamp, and, as a matter of course, to the researches
on argon and helium. The section on the metals has also been
written up to date, as here we notice the illustrations of the appa¬
ratus employed in the ammonio-soda process, a description of
calcium carbide, and mention made of the use of cyanide in gold
recovery. In all we have some forty pages of new and interesting
matter. The article on photography, which is a reprint from the
last edition, in its present superficial form might advantageously
be omitted, and the same might be said of the illustrations Nos.
57 and 73, which are more suitable to the capacity of those for
whom the manual is not intended.
Professor Tilden is to be congratulated on having again provided
a manual which may be regarded as one of the best of its kind for
all students of chemistry.
St. Thomas’s Hospital Reports, 1897. New Series, Vol. xxiv.
Edited by Dr. T. D. Acland and Mr. Bernard Pitts.
Pp. 510+118. London: J. and A. Churchill. 1897.
This volume, which contains the record of the work of St.
Thomas’s Hospital for the year 1895, and in addition, several
valuable original papers, is fully equal in interest to its prede¬
cessors. Among the original articles, one by Dr. F. R. Walters,
on an affection (pulmonary osteo-arthropathy) observed in some
cases of chronic lung disease, affords an additional example of the
great value of the Rontgen ray photography (skiagraphy) in
recording and discovering pathological changes. One of the
leading features of the disease is a thickening of the fingers and
toes. The excellent skiagrams by Dr. Blacker, which illustrate
thepapershow thatpartat leastof the thickeningis due to the forma¬
tion of new bone on the surface of bones of the fingers and toes. Dr. W.
Wellington Lake, Medical Officer of Health for the West Surrey
Districts, contributes an account of an outbreak of typhoid in a home
for invalids. The outbreak originated by the admission as an
inmate of a nurse who bore a certificate of freedom from infectious
disease, but who was found to be suffering from typhoid. Within
two months of this event ten persons developed the disease in the
institution, and two immediately after leaving it. The various
modes in which the outbreak might have originated were investi¬
gated. The water supply came from wells sunk in the chalk at
Albury Downs, and from the nature of the wells and previous
analysis was decided to be above suspicion. The water-cisterns
in the home were situated on the roof of the building, and were
far removed from drains and drain-ventilators. The milk and food
supplies were both excluded as sources of infection. The drainage
system was found to be extremely faulty, though the institution
was comparatively new and expensively built. Both the smoke
and water tests revealed numerous defects. The author of the
paper came to the conclusion that all save one of the cases arose
from gas escaping into the house from the drains in which was
typhoid material derived from the first case. The practical result
was the committee of the institution carried out extensive recon¬
struction of the drains. A paper by the late George Rainey is
reprinted from the Medical Times and Gazette of 1868, and is
entitled “The Artificial Production of Certain Organic Forms”;
phenomena of considerable interest in physiological chemistry.
The kind of pihenomena dealt with are the formation of microscopic
334
PHARMACEUTICAL JOURNAL.
[April 17, 1897
globules seen on mixing solutions of white and red gum, of hollow
tubules which form when crystals of chloride of barium are placed in
a saturated solution of sulphate of soda. Observed in a closed cell
under a 1-inch or ^-inch objective, the tubules can be seen to begin to
form around the dissolving crystals and to ascend from the bottom
to the top of the cell. Rainey concluded that the tubules con¬
sisted of crystals of sulphate of soda, and their ascent was deter,
mined by an elevation of temperature about the dissolving crystals
of chloride of barium.
There are other valuable articles, and the usual careful digest of
a year’s work at the Hospital. This digest is really a most eloquent
statement of the enormous amount of good and humane work that
is done gratuitously at St. Thomas’s Hospital.
PHARMACEUTICAL SOCIETY.
EXAMINATIONS IN LONDON.
April, 1S97.
MAJOR EXAMINATION.
Candidates examined . 32
,, failed . 12
,, passed . 20
Goupland, Henry Snart.
Coverdale, Arthur Edward.
Drust, John Hubert.
Elkington, Charles John.
Goodall, Frederic Charles.
Hopkins, John Sidney.
Hughes, William Griffiths.
Knowles, William Richard.
Lee, Harry Lancelot.
Lewis, Richard Rice.
Lloyd, Thomas Henry.
Lumley, Harold.
Mallaband, William Henry.
Saunders, Alfred Woods.
Stearn, Ralph Marmaduke.
Sutcliffe, Lot Bains.
Thomas, James Douglas.
Umney, Ernest Albert.
Walker, Albert Storrs.
Woodward, Harrison.
0 7 ''
Skinner, Ernest Pape.
Slater, Ernest Henry.
Snow, Leonard Hardy.
Stearn, Sydney.
Thompson, Sidney Cooke.
Tirrell, Arthur William.
Watson, Ralph Henri Louis.
Whysall, Edward Searson.
Williams, Joseph Miles.
Windemer, Oscar Roxburgh.
Woods, Benjamin Archibald.
FIRST EXAMINATION.
Certificates by approved examining bodies were received from
the under-mentioned in lieu of the Society’s examination : —
Barnett, Alfred Herbert ; Nantwich.
Breckon, Ralph ; East Harlsey.
Broad, William Allen ; Gt. Malvern.
Cannon, Herbert Henry ; Liskeard.
Clarke, William Fox ; West Kensington.
Davies, John ; Tewkesbury.
Dawson, Robert H. ; Wigan.
Fisher, Sydney R. P. ; Preston.
Flemming, Thomas H. ; Huddersfield.
Foster, Fredk. Horace Munn ; Rye.
Fullerton, David Noble ; Aintree.
Guard, Harry Ernest ; Kennington.
Hallsworth, H. Mainwaring ; Oldham.
Hawkes, Frederick ; Kennington.
Hughes, William Henry ; Birkenhead.
Hustler, George Herbert ; Horton.
Kirkpatrick, Arthur C. ; Edinburgh.
Little, Robert ; Wootton Bassett.
Macarthur, Malcolm James ; Glasgow.
MacS weeny, Eugene ; Nice.1]
Maloney, James Patrick ; Everton.
Moses, Walter William ; Oxton.
Nixon, John Hobart : Loughborough.
Padwick, Kingsley John ; Brighton.
Pick, John Thomas ; Barnsley.
Pike, Herbert William ; Andover.
Roberts, William R. ; Linthwaite.
Robinson, Emil ; Whitchurch.
Ruston, Edward ; St. Albans.
Sloman, Courtenay ; Torquay.
Smith, Francis Lewis ; Shareshill.
Smith, Reginald R. ; Weston-s.-M.
Taylor, William S. ; Enniskellen.
Tinsley, Samuel Hilton ; Widnes.
Walter, William H. ; Newcastle, Staffs.
Wamsley, William B. ; Stockport.
Westrope, Lionel L. ; Durham.
White, Daniel Hanbury ; Clifton.
“FIRST” EXAMINATION QUESTIONS.
April 13, 1897.
LATIN.
MINOR EXAMINATION.
Candidates examined . . 235
„ failed . . . 160
75
,, passed
Anquetil, Charles Edouard.
Arber, Alfred Preston.
Barlow, Thomas Oldham.
Barrett, Henry William.
Battle, Ernest Wm. Chatterton.
Bawcutt, Frank Frederick.
Bowdler, Ernest Harper.
Bromley, Albert William.
Brown, John Arthur.
Burnett, John.
Cassels, Thomas Henry.
Chapman, Edgar Marsh.
Cole, Claude.
Cooper, Herbert Edward.
Dowdy, Sidney Ernest.
Durrant, George Stuart.
Dutson, Robert Thomas.
Eustace, Robert George.
Evans, Arthur Edward.
Foster, Charles Ekins.
Gair, Emmeline Annie.
Gayton, Ethel.
Gittins, Samuel Ernest.
G william, John Everall.
Hamer, Enoch Thomas.
Hampton, William Henry.
Hicks, Alexander Frank.
Hooper, Joseph.
Jeffery, George Golder.
Jeffs, Richard Thomas.
Jones, Edward Rees.
Jones, Richard Robinson.
Jones, Stephen.
Kerruish, Thomas Maltby.
King, Frank Herbert.
Kissell, John Victor.
Knight, Thomas.
Knowles, John Thomas.
Lenfestey, Leopold d’Estreville.
Lester, William Hy. (Nuneaton).
Lloyd, Henry Bright.
Lounds, William Beaver.
Lowson, William.
Marsh, Ernest.
Marshall, Henry Herbert.
Matson, Joseph.
Mellor, William Gilbert.
Morgan, David King.
Morris, Henry.
Neale, Denys William.
Neale, John.
Nye, Gerald Launcelot.
Owen, Alfred.
Parker, Herbert Thomas.
Pearson, John Henry.
Peck, John Wicliffe.
Plant, Thomas.
Price, Edward George.
Purnell, Austin.
Rider, Ernest Alfred.
Siminson, Albert Henry.
Siviter, Wm. Oscar Bull.
Skeat, Charles.
Skeeles, Arthur Edward,
( Time allowed^from 11 a. m. to 12.30 p.m.)
I. For all Candidates. Translate into Latin
1. The sons had a good mother.
2. Was not the sea tempestuous ?
3. You and I will leave the city not unwillingly.
4. Two thousand men were slain ; only three hundred were captured.
5. He thinks that we must always obey the wise.
II. Translate into English either A (Caesar) or B (Virgil).
(Candidates must not attempt both authors.)
A. — Caesar.
1. Haec quum pluribus verbis flens a Caesare peteret, Caesar ejus dextram
prendit : consolatus rogat, finem orandi faeiat : tanti ejus apud se gratiam esse
ostendit, uti et rei publicae injuriam et suum dolorem ejus voluntati ac precibus
condonet. Dumnorigem ad se vocat ; fratrem adhibet ; quae in eo reprehendat,
ostendit ; quae ipse intelligat, quae civitas queiatur, proponit ; monet, ut in
reliquum tempus omnes suspiciones vitet ; praeterita se Divitiaco fratri condonare
dicit. Dumnorigi custodes ponit, ut, quae agat, quibuscum loquatur, scire possit.
2. Haec eodem tempore Caesari mandata referebantur, et legati ab Aeduis et a
Treviris veniebant : Aedui questum, quod Harudes, qui nuper in Galliam trans-
portati essent, fines eorum popularentur ; sese ne obsidibus quidem datis pacem
Ariovisti redimere potuisse : Treviri autem, pagos centum Suevorum ad ripas
Rheni consedisse, qui Rhenum transire conarentur ; his praeesse Nasuam et
Cimberium fratres.
Grammatical Questions.
(For those only who take Caesar.)
1. Give the gender and genitive singular of verbis, finem, se, dolorem, precibus,
ipse, civitas, tempus, custodes. (Passage 1.)
2. Give the third person singular of the indicative perfect and of the sub •
junctive present of all the verbs in Passage 2.
3. What is the difference in meaning between the singular and the plural of
copia, impedimentum, auxilium?
4. Point out the difference between ne and non, and write short sentences in
illustration.
B.— Virgil.
1. Arma virumque cano, Trojae qui primus ab oris
Italiam, fato profugus, Lavinia venit
Apbil 17, 1897]
PHARMACEUTICAL JOURNAL.
335
Littora ; multum ille et terris jactatus et alto,
Vi superum, saevae memorem Junonis ob iram.
Multa quoque et bello passus, dum eonderet urbem,
Inferretque Deos Latio : genus unde Latinum,
Albanique patres, atque altae moenia Bomae.
Musa, mihi eausas memora, quo numine laeso,
Quidve dolens regina Deum, tot volvere casus
Insignem pietate virum, tot adire labores
Impulerit. Tantaene animis coelestibus irae ?
2. Postquam introgressi, et coram data copia fandi,
Maximus Ilioneus placido sic pectore coepit :
O regina, novam eui condere Jupiter urbem,
Justitiaque dedit gentes frenare superbas,
Troes te miseri, ventis maria omnia vecti,
Oramus : prohibe infandos a nayibus ignes,
Parce pio generi, et propius res aspioe nostras.
Grammatical Questions.
(For those only who take Virgil.)
1. Give the gender and genitive singular of virum, qui, ille, vi, bello, genus ,
numine, pietate, animis. (Passage 1.)
2. Give the third person singular of the indicative perfect and of the subjunc-
^ ive present of all the verbs in Passage 2.
3. What is the difference in meaning between the singular and the plural of
copia, impediment-urn, auxilium ?
4. Point out the difference between ye and non, and write short sentences in
illustration.
ARITHMETIC.
( Time allowed— from 12.30 p.m. to 2 p.m.)
[The working of these questions, as well as the answers, must be
written out in full.]
1. How much coal will be required for 6 fires for 27 weeks, each fire consuming
1 cwt. 1 qr. 14 lbs. weekly ?
2. If 6 men, working 8 hours a day, could do t of a piece of work in 20 days, in
how many days could 15 men, working 10 hours a day, do l of it ?
3. What fraction is that from which if i of be taken, and the remainder
2 i
divided by the result is J ?
4. Express as a decimal fraction —
'fl of of 1?.
61
•416
5. How many times could -0007 of a shilling be taken from £41, and what
decimal of a penny would be left over ?
6. In a certain town of 987,648 inhabitants, 567 people died in a certain week.
Find, to two places of decimals, the death rate per thousand per annum.
The following question must be attempted by every candidate : —
7. Name the metric unit of length, and give its equivalent in English measure.
Express, approximately, the number of grammes equal to 9 cwt. 1 qr. 3 lbs.
ENGLISH.
( Time allowed— from 3 p.m. to 4.30 p.m.)
1. How does the accent of the following words affect their meaning ? — refuse
frequent, compact.
2. Analyse the following passage : —
“ Such were the sounds that o’er the crested pride
Of the first Edward scattered wild dismay,
As down the steep of Snowdon’s shaggy side
He wound with toilsome march his long array.”
3. Parse fully the following words in the passage given in Question 2 : — such,
that, o'er, as, down, wound, toilsome, array.
4. In the following passage supply the necessary capital letters, and put in
the stops and inverted commas where necessary : — for whom are you called out
an officer of the foot guards for the king replied a voice from the ranks of the
rebel cavalry for which king was then demanded the answer was a shout of king
monmouth mingled with the war cry which forty years before had been
inscribed on the colours of the parliamentary regiments god with us.
The following question must be attempted by every candidate : —
5. Write a short essay on
(i.) Some act of heroism of which you have read or heard;
or
(ii.) Changes in the social condition of the people during the reign of Queen
Victoria.
NATURAL HISTORY NOTES.
To Catch Earwigs. — The compound mentioned on page
335 is an admirable bait for earwigs. To catch these
pests both sides of some large flower- pots should be streaked
with the compound, then mounted on sticks in the usual
way. The stuff should be put on a little before sunset. In
half an hour the traps should be visited, carefully lifted
off the stick, held over a bucket of hot water, and sharply
tapped. The insects will fall in a shower into the water. In
another half-hour a fresh crop may be gathered.
To Drive Away Ants. — Probably pharmacists are more often
consulted on a means to drive away ants than on any other ento¬
mological subject, excepting the ever present “ blackbeetle,”
which is with us always. We have found that a solution of naph-
thalin in carbon bisulphide is excellent for outdoor use, but is of
course too dangerous to use indoors. For use in the house a
saturated solution of naphthalin in carbolic acid is almost equally
efficacious. Bisulphide is also effectual for destroying moles on
lawns, and for suffocating wasps. It should be poured down the
entrance to the nest at night and the orifice immediately closed
with a clod of earth.
The Homing Instinct in Animals. — An interesting paper by
James Weir in Lippincot’s Magazine entitled “ The Sixth Sense,”
treats of the remarkable “homing” instinct which is so marked
in many animals, and far from being confined, as is popularly
supposed to the more highly developed vertebrates, is found by
the author to be possessed in a very high degree by creatures so
low down the scale as the Mollusca. Last summer he marked six
snails with a distinctive paint and removed them some distance
from their home. In the course of time four reappeared in the
accustomed haunt, the other two having probably become the
prey of predatory blackbirds. Some beetles have the homing
instinct highly developed, notably the blind beetle, Adelops, of the
Mammoth caves, which when unmolested will rarely stir more
than sixty feet from its home. If carried away by force will
immediately commence its homeward journeyin an undeviating line.
That the domestic animals possess the same sense in a greater or
less degree is a matter of common knowledge. Experiments with
the lower forms are comparatively easy to conduct, and will
probably afford some interesting results.
Aquarium and Microscope. — Another unfailing source of
pleasure to the naturalist who is confined to home is the aquarium,
the more if the microscope be used to explore its wonders. Here
the sporadic appearance of certain forms of life at intervals will
form an interesting problem. Lately we had a number of Hydra
fusca infested with the curious parasite Trichodina ; suddenly the
Hydra totally disappeared. The same occurs with Melicerta
ringens, which comes and goes in our aquarium in the most
unaccountable manner. One year we get hundreds of individuals,
and then perhaps none for a year or two, when they again re-appear
in numbers. The water in the aquarium is never changed, but
keeps perfectly sweet and fresh.
The Season. — Spring now appears to be fairly upon us. The
winter aconite has supplanted the Christmas rose in the flower
beds, crocuses and snowdrops have had their turn, the
early primroses have taken courage and are showing the flowers
with some confidence. On railway banks that true harbinger of
spring, the coltsfoot, is now in full flower, elm trees are blooming,
and the flower buds on fruit trees are becoming prominent. Rooks,
true to the old saw, appear to have mated, and the house sparrow,
whose domestic virtues form the one redeeming trait in his other¬
wise villainous character, seems bent on nidifieation.
Blacking of Lathrea squamaria. — In a few weeks the early
botanist may hope to see Lathrea squamaria if he knows where to
look for it, but will be fortunate if he succeeds in drying a speci¬
men without its turning an unsightly black. It might be worth
while to try the effect of bibulous paper soaked in oxalic acid
solution and dried for preventing the discoloration of this curious
plant. This method, as has been recorded in our pages, is recom¬
mended by certain Continental botanists for preserving plant
colours. How far it has been successful we should be glad to hear
from such of our readers as may have tried it,
336
PHARMACEUTICAL JOURNAL.
[April 17, 1897
THE STUDENTS’ PAGE.
NOTES ON THE B.P.
Cinchona Rubre Cortex. — To ensure uniformity of material,
the Pharmacopoeia provides that the bark used for making the
galenical preparations of cinchona shall contain between 5
and 6 per cent, of total alkaloids, of which at least half shall be
quinine and cinchonidine. The reason for the latter proviso
is this : the medicinal value of the cinchona alkaloids is as
follows : — Quinine first, then quinidine, cinchonidine, cinchonine,
and lastly amorphous alkaloid. Quinidine usually occurs in com¬
paratively small quantities. The determination of total alkaloids
is therefore not sufficient, since a large proportion might be
cinchonine and amorphous alkaloid, and a bark, although
containing 6 per cent, of total alkaloids, would he of low
medicinal value under these conditions. The official assay
process needs little explanation. The trituration with lime
sets free the alkaloids from their combination with quinic acid,
and the alkaloids are dissolved out from the mixture by re¬
peated treatment with benzolated amylic alcohol. This fluid
dissolves also colouring matter and traces of other bodies, so that
simple evaporation to dryness would not yield a sufficiently pure
residue to be weighed as alkaloid. In order to separate the alka¬
loids from accompanying impurities a procedure is adopted, which
is very commonly employed in alkaloidal assays, viz. , the conver¬
sion of a dissolved substance into a condition in which it is more
soluble in a second, immiscible solvent than in the original
solvent. In the present instance this result is attained by
first adding dilute hydrochloric acid to convert the alkaloids
into hydrochlorates. These hydrochlorates are very slightly
soluble in benzolated amylic alcohol, but very freely in water,
especially in presence of an excess of acid. When the two
fluids have separated the lower aqueous layer will contain nearly
all the alkaloid, and reagitation with a fresh portion of water
removes practically the whole. It is advisable not to shake the
two fluids together too violently, otherwise they will emulsify to
some extent and not separate quickly or completely. If an
emulsified layer is in any case obtained only the pei’fectly clear
portion should be drawn off, and more solvent added to wash
the alkaloid out of the emulsified portion. Gently rotating and
warming will sometimes assist complete separation. Note
that the general rule in such separations is that the alkaloidal
salts, i. e. , in presence of acid, pass from oily or ethereal fluids
into water, and the free alkaloids, liberated from the acid aqueous
solution by addition of alkali, pass from water to oily or
ethereal solvent. This, of course, depends upon the fact that free
alkaloids are, as a rule, only slightly soluble in water, while their
salts, particularly in presence of excess of acid, are freely soluble
in water. The fluids, immiscible with water, most commonly
employed are ether, chloroform, benzene, and amylic alcohol, the
choice of fluid depending upon the solubility of the alkaloid dealt
with. The general statement which covers all these cases is as
follows : — When two non-miscible fluids are agitated with a sub¬
stance soluble in both, the substance distributes itself between
the two solvents in a ratio which is directly proportional to its
solubility in those solvents. From this it follows that the greater
the difference between the solubility of any substance in the two
fluids the more easily and completely is it extracted from the one
in which it is least soluble.
Cinchonidine Sulphas.— If the acidified aqueous solution be
fluorescent, quinine is indicated. Cinchonidine forms a very in¬
soluble tartrate. The filtrate from this will precipitate on the
addition of ammonia if cinchonine be present. Cinchona alkaloids
are not charred by sulphuric acid when gently warmed. Most
organic substances — e.g., sugar — which might be used as adulter¬
ants are easily charred.
Cinchonine Sulphas. — Compare tests for cinchonidine sulphate.
Confectiones. — These may be described as preparations of a
pasty consistence composed chiefly of sugar or honey, which are
used as vehicles and to render the confection palatable. Confec¬
tions of hips and roses are used as pill excipients. Confection of
senna is still a popular remedy. The senna is introduced in
powder, and its purgative action is assisted by the figs, tamarinds,
cassia pulp, and prunes. These, with the extract of liquorice and
coriander, very effectually cover the taste of the senna. The asso¬
ciation of carminatives (chiefly drugs containing essential oil), like
coriander, with purgatives is intended to prevent griping. With
the exception of confection of sulphur, the others are not often
prescribed, and, as a class, confections are falling into disuse.
Only the proportion of opium in confection of opium need be
committed to memory.
Cupri Nitras. — The action of copper on dilute nitric acid results
in the formation of copper nitrate and evolution of gas, chiefly
nitric oxide. If the acid be concentrated, nitric peroxide N02
is chiefly produced. Note that hydrogen is not evolved by the
action of metals on nitric acid as it is from dilute sulphuric and
hydrochloric acids. Nascent hydrogen is a reducing agent, and
liberation in presence of nitric acid results in the reduction of the
latter, and consequent formation of water and oxides of nitrogen.
The usual equation for the action of copper on dilute nitric acid —
3Cu + 8HN03 = 3Cu(N03)2 + 2NO + 4H30
is rendered more intelligible by a consideration of this fact. Thus
we may regard nitric acid as composed of nitric anhydride and
water (2HN03 = H20,N205). It is therefore clear that every two
molecules of nitric acid will oxidise six atoms of hydrogen if nitric
oxide be the result of the action—
2HN03 + 6H = 4H20 + 2NO,
and since copper is divalent, three atoms of copper will displace
six atoms of hydrogen—
3Cu + 6HN03 = 3Cu(N03)2 + 6H.
If strong nitric acid be employed, the reduction of the nitric
acid does not proceed so far, N02, nitrogen peroxide being chiefly
produced.
In this case two atoms of hydrogen effect the reduction : —
(i.) Cu + 2HN03 = Cu(N03)2 + 2H
(ii.) 2HN03 + 2H = 2H20 + 2N02
Ferrocyanide of potassium is a delicate test for copper, on account
of the deep red colour of the insoluble copper ferrocyanide. The
black ring, produced in the usual test for nitrates with sulphuric
acid and ferrous sulphate, is due to the formation of a black com¬
pound of nitric oxide and ferrous sulphate. The sulphuric acid
liberates nitric acid; this oxidises a portion of the ferrous sulphate,
nitric oxide being produced by its consequent reduction, and the
nitric oxide forms the black compound with some unoxidised
ferrous salt. If the nitric acid be present in sufficient quantity
to convert the whole of the ferrous into ferric salt, the black com¬
pound disappears and the nitric oxide is evolved {vide Liq. ferri
persulphatis).
THE FLOWERS OF APRIL.
Taraxacum officinale (Compositse). — The common dandelion is
often found in blossom early in the year. The features worth
noticing in it are the absence of an aerial stem, which is repre¬
sented by a root-stock or upright underground stem, having
annular marks indicating where leaves have fallen off, and often
giving rise to latent buds, whereby the top of the root appears to
be branched. The leaves are runcinate, i.e., re-uncinate, having
the lobes turned backwards. The inflorescence arises direct
from the ground (scape) and the stalk is hollow (fistulose), the
florets, 100-200 in number, are all strap-shaped (ligulate), and there¬
fore the plant belongs to the sub-order Ligulifiorte. The calyx
tube is developed beyond the fruit in a kind of beak, and the
limb in the form of unbranched (pilose) pappus. The fruit,
which judging from the presence of two stigmas in the
flower should be two-celled, becomes only one-celled (cypsela), and
contains one seed. Externally it is covered with minute erect
spines pointing forwards, which when the fruit settles on the
ground and is washed by the rain and thus elongated, cause
it to enter the soil and prevent its working its way out again.
The leaves vary exceedingly in form and size, and in the
variety erythrocarpum are so narrow and so deeply cut that the
plant hardly seems to belong to the same species ; and in the
variety palustre they are almost entire. The flower-heads are very
sensitive to light, and at night and during rain the phyllaries close
up the flower-head, hence, if put in a botanical box, the flowers
become closed up. They should therefore be put between paper as
soon as gathered. The florets can be either cross oFself-fertilised. — -
Lubbock, l.c., p. 119.
Apbil 17, 1897]
PHARMACEUTICAL JOURNAL.
337
Pharmaceutical Journal.
LONDON: SATURDAY, APRIL 17, 1897.
ON TECHNICAL EDUCATION.
The subject of technical education continues to be one of
the burning questions of the hour, but light is gradually
being thrown on the absurd demands and suggestions that
are so prevalent, and by and bye we may hope to see the
matter dealt with on a proper basis. The latest contribution
to the discussion is by a writer in the University Extension
Journal , and it possesses the importance that naturally
attaches to arguments based on sound common sense. For
example, it is pointed out that technical instruction in
the principles of the art of swimming might be very complete,
but it would be necessary for the student to enter the water
before he would be able to swim, and similarly, it is urged, we
are confronted with the practical impossibility of teaching any
craft without actually engaging in the industry or employment
concerned. A very inferior shoemaker could make a much better
pair of shoes than the scientific man who knows all about
leather, the shape of the human foot, and the principles on
which a perfect shoe ought to be made, but who has never
been trained in the art and mystery of shoemaking.
Though it is now generally admitted that, in many depart¬
ments of what used to be called “ unskilled labour,” a much
greater degree of skill is required than was at one time
thought to be necessary in order to secure a living wage,
“ no technical instruction is needed in these departments
beyond what can be fully obtained by the continued practice
of the employment.”
But in addition to these so-called “ unskilled employ¬
ments” there are the numerous crafts and occupations in
which preliminary education is necessary, and in which, if
the highest efficiency is to be achieved, technical education
is also necessary. In almost every craft, it is contended,
there is only sought that degree of excellence and efficiency
which may be called the “ market standard.” Manufactures
which do not reach this standard, or which do not possess
the appearance of being up to this standard, are rejected by
traders, and the manufacturers fail in their object. “ There
is beyond the present ‘ market ’ or utilitarian standard
a most desirable standard of artistic excellence, where the
best material, the best designs, and the best workmanship
are combined in order to secure the finished product, whether
it be a thing for use or for pleasure. There are very few
manufactories indeed where workmen and the whole of the
resources of the manufacturers are engaged in producing the
very best results of which art and science are capable. The
reason given for this non-production of the best things is
that there is no market for them — they will not pay. Many
things are only required to serve a passing occasion, and
it would be sheer waste to expend on their manufacture
either labour or mateiials or skill beyond what the temporary
occasion justified.”
What is needed in this country, continues the writer, is
by means of technical education to bring a higher degree of
skill into every workshop in the land, so that handicrafts¬
men in every craft may be enabled to turn out more durable,
more beautiful, and more excellent things, whether for
practical business use, or fo~ consumption, or for the gratifi¬
cation of the senses. To make this possible and profitable,
the public must be technically educated so as to be able to
appreciate beauty, excellence, and efficiency. But it can
scarcely be contended that the Technical Instruction Act, as
at present administered, is doing this work, and it is sug¬
gested that to accomplish this end technical education must
pick up the handicraftsman at the point where the average
workshop leaves him, and must begin at that point to elevate
his taste and to perfect his skill. “Though the weaver
weaves shoddy, he learns more of the art of weaving in a
mill than he can learn elsewhere, for it is only by weaving
something that he can learn to weave at all,” and what is
true of the weaver is true also of the builder and of workers
in metal, wood, glass, clay, and other materials.
The place where the particular craft is practised on
business lines is truly described as being in the first instance
and up to a certain point, the really efficient technical school.
This is as true of pharmacy as of any other craft, but
when the pupil has learned all that can be taught
in the pharmacy or other primary technical school,
conducted for the purposes of profit, it is necessary, in
order to complete his education, that he should proceed
to places of technical instruction “ fitted up with the best
appliances, where the best material is used, where the best
designs are worked from, and where the best workmanship
is secured, in order that the things produced may be good
throughout.” With regard to the young workers found from
time to time in every workshop in the land, who reveal
more than average skill and insight, it is urged that they
ought to be pecuniarily helped to pass through a period of
advanced technical education, so that they may be in some
way or other employed in advancing the average skill of
the ordinary workman.
To secure the sort of advanced technical education advo¬
cated without an enormous outlay, the suggestion is made
that the educational institutions of each county might be
brought into working relations with the Public Works
Departments of County Councils, as such bodies ought to do
the best work in the best ways. “ There is nothing to
prevent technical workshops being established for leather
works in Bermondsey and Northampton ; for weaving in
Nottingham, Manchester, Bradford, and elsewhere; for mining
in Cardiff ; for navigation in London and Liverpool ; for engi¬
neering at Newcastle; and so on for every branch of industry.”
The greatest difficulty to be overcome is thought to consist, not
in finding means to give advanced and scientific instruction
in the various crafts, but in persuading those who have the
direction of technical education that the knowledge to be
obtained by youths in schools and colleges is not the tech¬
nical education that is likely to enable this country to meet
its competitors in the markets of the world on more favour¬
able terms than at present. “ There are thousands of good
workmen scattered all over the country who could be made
into real masters of their arts if technical instruction could
be placed within their reach on terms that would enable
them to avail themselves of it. If some scheme of this kind
were instituted as opportunity afforded, and if the old
system of apprenticeship were revived, technical education
would become a reality.” What is suggested may not be
readily attainable, but it is well worth any effort that may be
made to secure it. Technical education, commencing in the
shop and continued in the college, is the true ideal, and in
pharmacy at least it is both practicable and necessary to the
complete development of the art.
338
PHARMACEUTICAL JOURNAL.
[Apbil 17, 1897.
ANNOTATIONS.
The Case at Nottingham, reported on page 342, affords an
instance of the extreme difficulty of securing evidence in many
instances where it is well known that infringements of the Phar¬
macy Acts are continually taking place. Fortunately, however,
the facts marshalled by Mr. Grey proved conclusive, and defendant
met with no abnormal sympathy on the part of the County
Court J udge. As so frequently happens nowadays, the
point was raised that defendant was not notified when
the purchase was made, but the Judge made short work of
the argument based on that fact. As he pointed out, the Pharma¬
ceutical Society is not bound to give any warning, and comparison
with the Food and Drugs Act is quite beside the question, as the
terms of that Act are very different, whilst it defines its own
method of procedure. Neither would His Honour allow that the
Society was to be blamed for the course taken in the case, as the
doctor, on behalf of whom the sale was made, knew well the serious¬
ness of allowing an unqualified person to sell poison and, as a
medical man, should know how important it is that the require¬
ments of this Statute should, for the safety of the public, be
strictly adhered to and its provisions enforced against infringers.
Amendment of the Patent Laws is badly needed in many
respects, and an influential deputation waited upon Sir Courtenay
Boyle last wreek to emphasise that fact, more especially in
regard to Section 22 of the Patents, Designs, and Trade
Marks Act, 1883. That Section was drafted with the object of
preventing foreigners taking out patents in this country without
any intention of working them here. It is contended, however, in
certain quarters, that the dog-in-the-manger policy aimed at
prevails more widely than appears to be officially known. Hence
the present movement in defence of home interests. Section 22
provides that if — on the petition of any person interested,
it is proved to the Board of Trade that, by reason of
the default of a patentee to grant licences qn reasonable
terms, ( a ) the patent is not being worked in the United
Kingdom ; or (b) the reasonable requirements of the public
with respect to the invention cannot be supplied; or (c)any person
is prevented from working or using to the best advantage an
invention of which he is possessed — the Board may order the
patentee to grant licences on reasonable terms, and any such
order may be enforced by a mandamus.
The Obvious Intention of the Section, as urged by Sir W.
Houldsworth, M.P., on behalf of the deputation, is to insure that
any patents granted in this country shall be available for use in
this country, and that if for any reason a patent be allowed to lie
dormant by default, the Board of Trade has power to step in and
insist that a licence shall be granted on such terms as the Board
may deem just. When the Section was drafted the intention was
that patents should not be allowed to lie dormant, but it is
alleged that the Section has been practically a dead-letter, mainly
through its own inherent weakness. In replying to the arguments
adducedby the members of the deputation, the Permanent Secretary
to the Board expressed adoubt whether the condition of affairs wasso
bad as stated. Only four applications to take action under Section 22
had been received, and those were never proceeded with. Before
it can be said, therefore, that the Section is absolutely inadequate
for its purpose, it ought to be clearly shown that there is no
other procedure by wThich the same result can be secured. It is
Suggested that carefully selected cases should be made the subject
of application under the Section, where there is default of the
patentee to work his patent in the United Kingdom, and that the
Board might then be pressed to take proceedings under the Act.
The Sale of Medicated Wines by Chemists does not necessitate
the holding of an excise licence, provided the wines are really
medicinal, but if a licence be obtaine 1 the retailer is entitled to sell
any wine, whether medicated or not. Moreover, it is not within the
discretion of magistrates to withhold a licence when it is applied
for by an individual of good character. Occasionally, when a
chemist is the applicant, an attempt is made to impose restrictions
as to the character of the wines to be sold, but such steps are not
legally justified, and an appeal recently heard by the Surrey
County magistrates emphasises that point. A licence for the off-
sale of wines had been granted by the Kingston Borough magis¬
trates on condition that medicated wines only should be sold, and
when an undertaking to that effect was broken, the magistrates
refused to renew the licence. On appeal, however, it has been
clearly shown that the borough magistrates had exceeded their
powers, and acted illegally. The appeal was therefore granted,
and the appellant will now be able to secure his licence without
any unusual conditions being imposed.
In Commenting on this Case the Daily Telegraph permits
itself to take a totally unjustifiable view of the matter. Assuming
that the success of the appellant was due, not to intrinsic merits,
but to the opinion of the Court of Quarter Sessions that the
magistrates were not entitled to impose the conditions they did pn
the licence, the hope is expressed that the case will raise the whole
question of the sale of what are called ‘ ‘ medicated ” or “ invalid ”
wines, the trade in which is alleged to be growing to enormous
proportions. That may or may not be true, but it certainly does
not justify the Daily Telegraph in suggesting that chemists and
druggists encourage this branch of trade and facilitate secret drink¬
ing. Many persons, it is stated, especially women, who would dis¬
dain to enter a public-house for a bottle of whisky, think nothing of
carrying away a bottle of medicated wine from a drug store, and the
effect of one article is pretty much the same as the other. It may
be doubted, however, whether the writer of those remarks would
find the effects “ pretty much the same ” if he got intoxicated on
quinine or coca wine in place of port or champagne. But the absurd
suggestion that chemists encourage drunkenness is not original
with our contemporary, as it is merely copied from an equally ill-
informed medical organ. With regard to the “rather curious
anomaly that while the manufacturer of ginger beer is pounced on
by the Inland Revenue should he allow a scintilla of alcohol to
pervade a pint, druggists are at liberty to sell quarts of alcohol if
only it contain a flavour of some drug or other,” we can only
recommend the person who discovered this seeming “ anomaly ” to
make more certain about the accuracy of his statements before
publishing comments on technical matters he does not comprehend.
Coroners are only Mortal, and some few are amazingly fer¬
tile in discovering methods by adopting which chemists could
readily make their lives a burden. In a case reported from Sheffield,
where a file-cutter had committed suicide by drinking laudanum,
Coroner Wightman, not content with the restrictions at present
imposed by the law, said that, in his opinion, chemists should not
be allowed to sell laudanum without writing on the label the date
on which the poison was sold, and also the name of the person to
whom it was sold. As the law stood at present the public could
purchase laudanum in every little grocer’s shop (sic), as well as the
April 17, 189?]
pharmaceutical journal.
339
best appointed chemist’s shop in Sheffield, and he thought it was
time something was done to alter the law in this respect. Now, if
Mr. Wightman knows this to be the case, he ought to communi¬
cate with the Secretary of the Pharmaceutical Society and not
content himself with talking at large to jurymen. The law as it
stands is quite capable of dealing with the matter : coroners
ought to know that and do all they can to put it in force.
Mr. Thomas Hanbury has presented a drinking fountain to the
town of Mentone and the Society for the Protection of Animals,
and it was formally handed over to the charge of the Mayor of
Mentone on Saturday last, in the presence of Princess Victoria
of Schleswig-Holstein, grand-daughter of Queen Victoria, who
subsequently visited Mr. Hanbury’s residence at La Mortola.
A Few Choice “ Lots” are mentioned in the Lancet, in a note
referring to the difficulties experienced by country printers in
setting up technical medical terms. The document commented on
was headed “ The Late Dr. Blank’s Sale of Household Goods. Copy
from Catalogue,” arid contained the following : — Lot 471, a
Haryngscope in case ; 746, two silver cathetus in case ; 747, Wet
capping instrument in case ; 748, Shphygniograyh (Mareys) ; 755,
Syringe (Waginal) ; 759, Trocars and Camicula in case ; 766, Mid¬
wifery Bags, Forceps, long and Rigot Case inside ; 774, Frocar and
Camicula; 775, Minnim Measles iri Box; 781, Hosh (double)
(? truss) , 785, Hypodermis Case ; 804, Box of Cathartics ; 806,
Porcelain Pressary ; 822, Tensillotome ; 827, Gynelological Instru¬
ments, &c., iri paste-board box. Amongst books were mentioned :
839, Practical Orthop Acdiess, by Reeves ; and 854, Human
Orthology.
A Physical Laboratory for India is the latest idea projected,
a memorial having been handed to the Secretary for India, in
which the signatories draw his attention to the great importance
which they attach to the establishment in the Indian Empire of a
central laboratory for advanced teaching and research in connec¬
tion with the Presidency College, Calcutta, the most important
educational institution under the Government of India. They
believe that it would not only be beneficial in respect of higher
education, but also that it would largely promote the material
interests of the country, and they venture, therefore, to urge the
desirability of establishing in India a physical laboratory worthy
of the Empire. The memorial bore the following names : — Kelvin,
Lister, W. Le W. Abury, R. S. Ball, W. G. Bond, E. T. Carter,
R. B. Clifton, G. Carey Foster, G. F. Fitzgerald, W. Garnett,
J. H. Gladstone, J. Hopkinson, W. Huggins, J. H. Poynting,
W. Ramsay, H. E. Roscoe, A. W. Rucker, A. Schuster, G.‘ G.
Stokes, W. Stroud, S. P. Thompson.
The ‘ United States Pharmacopoeia ’ is looked after by a
permanent committee of revision and publication, and that com¬
mittee appears to be at work continually, commencing directly
after the current Pharmacopoeia is issued from the press. The next
U.S.P. will be that of 1900, and the committee has just published
the first part of a digest of criticisms and suggestions for improve¬
ment of the text at present in force. This compilation consists of
abstracts embodying information published in all the leading
journals and books treating of the subject matter of the national
pharmacopoeia. It practically represents pharmaceutical literature
published between the publication of the 1890 U.S.P. and July 1,
1896, and corresponds roughly to Dr. Attfield’s annual reports on
the British Pharmacopseia, but is, of course, the outcome of a
system which unfortunately has no parallel in this country.
The Royal Botanic Society of London, at a meeting held
last Saturday, was entertained by the Secretary, Mr. J. B.
Sowerby, with an interesting account of the cultivation and manu¬
facture into paper of esparto grass. The lecturer’s remarks were
illustrated by specimens and growing plants from the gardens.
The plant producing it (Stipa lenacissima) is capable of living
under the most adverse conditions, being often found flourishing
in desert places where no other vegetable life can exist, and it was
suggested by the lecturer that this would be a most suitable plant
for reclaiming the deserts of Sahara and turning them into a source
of profit.
The Registration of Plants is to receive attention to a limited
extent at the hands of a committee appointed by the Association
of American Agricultural Colleges, the idea being, according to
Science, to have some one place in the United States where all
plants placed upon the market can be officially registered, num¬
bered, and a description, together with specimens of the bloom,
seed, foliage, and fruit, placed on record. Coloured casts are to be
prepared when it is not practicable to preserve the originals, as in
the case of citrons, drupaceous and pomaceous fruits, and vegetables.
Specimens of flowers, fruit, root, tuber, or seed must accompany
all plants sent for registration, and vegetables must be accompanied
by a sufficient amount of seed to grow plants for identification. It
is also proposed to utilise the seed for the purpose of noting the
duration of cultural varieties, as well as the influence of climate
during any series of years or in any locality.
The Detection of, Potassium Compounds by the flame test is fre¬
quently an operation of some uncertainty, but according to Nature,
Mr. S. G. Newth, of the Royal College of Science, has invented a
little instrument which is free from the defects of the indigo prism.
As is well known, owing to the fact that indigo transmits the red
rays given by lithium, strontium, calcium and barium compounds,
as well as the red of potassium, salts of those metals, when heated
in a Bunsen flame, while the flame is examined with an indigo
prism, may be mistaken for those of potassium. Mr. Newth’s
instrument, however, is said to absorb not only the green and
yellow portions of the spectrum, but also the red, very nearly as
far down as the potassium line, and quite beyond the red lines of
lithium, strontium, calcium and barium. It is therefore opaque to
the red light given by those metals, while being transparent to
the red light of potassium ; and it is claimed for it that it allows
of the certain detection of potassium in the presence of any of the
metals commonly associated with it.
The Use of the Nile as a Source of Electricity is a natural
outcome of the harnessing of Niagara, and Professor George Forbes,
F.R.S., who played an important part in the latter operation, has
expressed a highly favourable opinion about utilising the waste
power of the Nile cataracts for generating electric currents. He
has been making an extensive tour in many parts of the globe
with a view to reporting on the utilisation of water power for the
generation of electrical energy. Amongst other places he has visited
New Zealand and Africa, and especially Northern Rhodesia. As a
result, a scheme is on foot for using the water power of the Victoria
Falls on the Zambesi River to generate electricity, and supply it
to the various centres of population throughout Rhodesia.
The Pharmaceutical Journal Office and the Pharmaceutical
Society’s premises generally will remain closed, on account of the
Easter vacation, from 5 p.m. on Thursday, April 15, until 9 a.m,
on Tuesday, April 20.
340
PHARMACEUTICAL JOURNAL.
[April 17, 1897
MEETINGS Op SCIENTIFIC SOCIETIES
- ♦ -
Linnean Society of London, Thursday, April 1. — Dr. A.
Gunther, F.R.S., President, in the chair. — Professor Graf zu
Solms-Laubach, the Rev. Robert Usher, and Mr. William Martin-
dale were admitted, and Messrs. J. B. Sowerby and J. C. Willis
were elected Fellows of the Society.
Feather Cloaks.
Mr. Miller Christy, exhibited three royal state cloaks formerly
worn by the kings of the Hawaiian Islands and made of the
feathers of four species of birds, of which the exhibitor gave an
account, referring to the coloured figures of them given in Mr.
Scott Wilson’s ‘ Birds of Hawaii,’ namely, Vestiaria coccinea (red),
Psittacirostra psittacea (green), Acrulocercus nobilis, and Drepanis
pacijica (black and yellow). The last named, of which no specimen
is to be found in the national collection, was believed to be now
extinct. — Mr. W. T. Thiselton-Dyer next exhibited a series of
drawings (on the screen) to illustrate the
Cultural Evolution of Cyclamen Latifolium, Sibth.
The species is a native of Greece and the Levant, and is believed to
have been first introduced into European cultivation in 1731. In
1768 Miller described a form modified by cultivation under the
name of Cyclamen persicum. This was erroneous, as, according to
Boissier, neither the wild nor the garden form occur in Persia.
The latter persisted in cultivation for about 150 years, and about
1860 became the starting-point of the modern races which were
illustrated. Cyclamen latifolhim has never been hybridised,
and it was shown that the striking forms now in cultiva¬
tion were the result of the patient accumulation of
gradual variations. Drawings of the remarkable forms
“ Papilio,” obtained by de Langhe-Vervaene, and of “ The Bush-
Hill Pioneer,” by Messrs. Hugh Low and Co., were shown. It was
pointed out that the tendency of the species under cultivation was
to lose its distinctive generic characters and to approximate to a
more generalised type. The reflexion of the corolla-segments was
often lost as in Lysimachia, the segments were sometimes multi¬
plied as in Trientalis, and the margins were fringed as in Soldanella
and cultivated forms of Primula sinensis. The “ Bush-Hill
Pioneer ” possessed, in the cresting of the petals, a remarkable
character without parallel in any primulaceous plant occurring in
a wild state. A series of plants was also exhibited to illus¬
trate the
Origin of the Garden Cineraria.
It was generally agreed that this had sprung from one or more
species native in the Canaries. An extreme cultivated form was
shown and compared with Senecio eruentus, which all internal
evidence indicated as the sole original stock. S. Heritieri,
another reputed parent, was exhibited. But it was pointed out
that this has a shrubby habit and stems markedly zigzag between
the internodes, while the leaves are clothed beneath with a dense
white tomentum. These characters it transmits more or less to its
hybrid offspring. In illustration of this point Mr. Poe’s hybrid
( S. super- Heritieri x eruentus ) was exhibited (a similar one has
occurred at Edinburgh) ; also the Cambridge hybrid ( S. super-
cruentus x Iler-itieri J. 8. eruentus crosses very freely with
the garden Cineraria, and as the latter never exhibits
any trace of the characters of *8. Heritieri, it was concluded that
that species had no part in its origin, and that, as in the case of
the Cyclamen, the striking development of A. eruentus in cultivation
was due to the continued accumulation of gradual variations.
Mr. A. W. Bennett exhibited a series of drawings by Mr. E. B.
Green of
Root-Hairs of Plants
with various parasitic growths, and showed preparations of several
under the microscope. Mr. G. R. Murray exhibited several lantern-
slides of
CoCCOSPHERES AND RhABDOSPIIERES.
prepared from specimens collected by Captain Milner of the
s.s. “ Para” while on a voyage to Barbados, including all the forms
figured in the “ Challenger ” report. Of these remarkable organisms
Mr. Murray gave a detailed account, explaining the formation of
coccospheres (so named by Dr. Wallich) as the aggregation into
spheres of the so-called coccoliths described by Huxley from deep-
sea soundings taken in the North Atlantic by H.M.S. “ Cyclops.”
The calcareous scales (or coccoliths) were shown to overlap each
other, and to constitute not only a defensive armour, but, from
their arrangement, to admit of the growth of the organism, which
is thus not limited by its calcareous coat, as diatoms are by their sili¬
ceous shells, each coccolith being attached to the cell by a button -
like projection on its inner surface. In the rhabdospheres with
projecting rods, of which figures were shown, the plates (Rhabdo-
liths) do not fit into each other as figured in the “ Challenger ” Re¬
port, but their bases are imbedded on the surface of the cell each
by itself without contact. As to the cell-contents, the ex¬
hibitor had found nothing more than a granular material re¬
sembling protoplasm. There was no trace of colouring-matter in
the specimens, all of which had been brought up from a depth of
three fathoms. — Mr. H. Groves exhibited a large number of
Charace.e
collected by Mr. T. B. Blow in various parts of Australasia and
Asia, views of the localities referred to being shown on the screen
by the collector. — Mr. George Massee, on behalf of Miss Helen
B. Potter, communicated the substance of a paper on the
Germination of Spores of Agaricine/g,
whilst a paper by Dr. A. J. Ewart on the Evolution of Oxygen
from coloured Bacteria was deferred for reading until May 6
next.
THE WORLD OF PHARMACY.
- - * -
BUSINESS MEETINGS.
Chemists’ Assistants’ Association, Thursday, April 8. —
Mr. Charles Morley, President, in the chair. — After the prelimi¬
nary business and the addition to the roll of one new member, a
paper on
Antitoxins
was read by Mr. F. W. Gamble, who commenced by remarking
that pharmacy has been aptly termed the handmaid of medicine,
and that medicine exercises her influence upon pharmacy chiefly
through materia medica, which in its broadest sense includes all
substances used in medicine, whether belonging to the animal,
vegetable, or mineral worlds. In dealing with the subject of his
paper, Mr. Gamble endeavoured to treat it from a purely pharma¬
ceutical aspect. Antitoxins, he said, are substances which
neutralise specific poisons or toxins and render them innocuous
The toxins may be chemical products of the metabolism of virulent
bacteria, or they may be bodies isolated from vegetable tissues. In
either case a sufficiency of antitoxin mixed with a lethal dose of
toxin prevents or moderates the train of symptoms characteristic
of the latter. Before dealing with the methods of producing
antitoxins, Mr. Gamble explained at some length a few
points in the „ life-history of bacteria, which have an
important bearing on the subject. He described the various
kinds of bacilli, and the conditions most favourable for the culti¬
vation of bacteria. He then touched upon the rapidity with which
animals become immunised to poisons, instancing the way in
which a tolerance of diphtheria toxin is produced in the horse by
repeated injections during several weeks until finally enormous
doses of toxin, and even an injection of virulent microbes can be
borne with but little reaction. The methods of producing diph¬
theria toxin, tetanus serum, vaccins, etc., were next described,
and the observations which gave rise to Coley’s fluid, which is a
sterilised culture of bacillus prodigiosus and bacillus erysipelatis,
and is occasionally used in some forms of cancer by hypodermic
injection at the seat of the disease. Natural immunity
was then explained, and artificial immunity by some, said
Mr. Gamble, is considered to be caused by a stimula¬
tion of the cells conferring natural immunity. These cells,
the leucocytes, or white corpuscles of the blood, are described
as the protectors of the body against its microbial enemies.
The nature of antitoxic bodies is but little understood ; they were
at first supposed to be chemical antidotes, but this theory was
disproved by an experiment of Professor Calmette, in which a mix¬
ture of snake venom and antivenin, its particular antitoxin, was
xound to be innocuous. When the mixture was heated to 80° C.
APEIL IT, 189?]
PHARMACEUTICAL JOURNAL.
341
the antivenin was destroyed and the full toxicity of the venom
returned. The effects of various serums upon their respective
microbes were next described and also the methods of sending
out curative serums.— Mr. Morley said that he had come to
the conclusion that although at the present time chemists are
men of many parts, in the future, in order to keep in the fore¬
most ranks of pharmacy, they will have to make themselves
familiar with yet another subject — bacteriology. — Mr. G. E.
Pearson had evidently been of the same opinion for some
time past, his remarks showing that looking forward to the
day when a knowledge of bacteriology will be of great
advantage to the pharmacist, he had carefully studied the science
and had acquired a fairly comprehensive grasp of the subject. —
Mr. Summers wished to know if the so-called typhoid antitoxin
had been prepared and used to any great extent, and with what
measure of success ; also the reason why sewer men, who continu¬
ally come in contact with sewer gas, scarcely ever contract
typhoid ? — Mr. Rogers thought the time has come when it
behoves every chemist to give serious attention to the treatment of
diseases by the various serums. Whether it would be as profit¬
able as making up bottles of medicine or not, it was undoubtedly
the coming treatment, and every chemist should be able to handle
intelligently the things asked for. He thought the paper read by
Mr. Gamble would reflect very great credit on the Association,
and should serve as a stimulus to the members generally to take
an interest in the new treatment and in all new treatments. — Mr.
Gamble replied to the various speakers, and referring to Mr.
Summers’ questions, he said that, so far as he was aware, typhoid
antitoxin had not been used with any very great success. With
regard to sewer men, he thought their immunity to typhoid was
largely due to their being used to contact with foul sewer gas.
Pharmaceutical Society of Ireland, Wednesday, April
7. — Mr. W. P. Wells, President, in the chair. — The President
stated that on March 23, a deputation consisting of the
Vice-President, Mr. Grindley, and himself waited on the
Inspector-General of the Royal Irish Constabulary, and asked
him to direct the members of his force throughout the country
to assist the Council in carrying out the
Pharmacy and Poisons Acts.
He received them very courteously and intimated that he
would take care that the police carried out the Poisons Act, and
asked that the Council would bring under his notice the facts of
any particular cases, but that as regarded the Pharmacy Acts he did
not see his way to the police taking action, but that they would
assist the Council.— A letter from Sergeant Doherty, Royal Irish
Constabulary, Enniscorthy, reported that John Kinsella, an assistant
in the Enniscorthy Co-operative Society’s Stores, had been fined £5
for selling Hayward’s sheep-dip without being legally qualified to
do so, but that the magistrates had suspended the levying of the
fine, as the defendant purposed appealing to the Lord-Lieutenant to
remit the penalty. The President mentioned that, at the hearing
of the case, the solicitor for the Society objected to one of the
magistrates taking part in the proceedings because he was chairman
of the company to which the defendant belonged, and to another
because he was a member of it. One of these magistrates became
very wroth, but eventually both left the bench. — On the motion of
the Vice-President, seconded by Professor Tichborne, it Avas
referred to a committee of the Avhole Council to draft an address of
Congratulation to Her Majesty
on the occasion of her accomplishing the sixtieth year of
her scwereignty, and also to consider whether, by any social
function, the Society could join in the public celebration
of the event. — The Vice-President also moved the addition to the
Regulations of three clauses to enable the School Committee to
arrange for the holding at intervals of meetings of an
educational character to which members and registered
students should be admitted free, prizes might be given and ex¬
penses paid out of the profits of the School Fund. This was
seconded by Mr. Grindley and agreed to. — On the motion of
Professor Tichborne, seconded by Mr. Conyngham, it was resolved
to re-establish a rule which formerly existed that elementai’y
theoretical chemistry should be a compulsory subject in the Pre¬
liminary examination. — On the motion of Mr. Conyngham,
seconded by Professor Tichborne, it was resolved to issue a
circular letter to pharmaceutical chemists, chemists and druggists,
and registered druggists, calling their attention to the benefits
which they would derive from being members of the Society, and
inviting them to join it. The Council then adjourned.
Pharmaceutical Society of Ireland. — Preliminary Exam¬
ination. — The following have passed: — Messrs. A. 1ST. Yoxall,
M. F. Brennan, J. B. Doran, G. E. Robinson, C. G. Keers,
T. G. Rutherford, J. Hunter, J. Walsh, H. J. Ovvgan, J. A. Walsh,
F. J. B. Alason, T. MacKay, R. R. Lowe. Nine candidates were
rejected. — Mr. E. B. Aplin has passed the Registered Druggist
examination. — Mr. H. Harris has passed the Pharmaceutical As¬
sistant’s examination.
Midland Chemists’ Assistants’ Association, Wednes¬
day, April 7. — Mr. Laavton in the chair. — Mr. John Barclay,
B.Sc. (Lond.), read a note on the
Coca Wine of Commerce,
in which he explained that two classes of coca wine are met with
in commerce, one agreeable in taste, and to be regarded as a
beverage, the other a medicinal preparation containing sufficient
of the active principles of the coca leaf to render it valuable as a
medicine and objectionable as a beverage. The first-named kind
of coca wine can only be sold by those holding wine licences, while
the latter, providing it satisfies certain requirements of the Board
of Inland Revenue, may be sold without restrictions. The position
of the Board of Inland ReArenue in the matter is represented by
the following quotation from a letter received from the Assistant
Secretary to the Board : — -
“The Board of Inland Revenue .... do not regard coca wine as non-
excisable uuLess it contains at least half a grain of cocaine to the fluid ounce,
and also a sufficient quantity of the extractive matter from the coca leaves
to render it unfit for use as a beverage.”
The following table showed the result of the examination of nine
commercial samples of coca wine : — -
Coca Wine of Commerce.
No. of
sample.
Description.
Specific
gravity at
16-5 C.
Absolute
alcohol by
weight
(per cent.).
Total
extractive
dried at
100' C.
(per cent.).
Grains per
fluid ounce
of total
alkaloid.
1 .
Excisable
1-032
16-70
12 -S2
0-10
2 .
Excisable
1-042
14-84
15-50
0 075
3 .
Excisable
1-014
17-17
8-81
0-066
4 .
Non-excisable
1-001
17-17
5-03
0-33
5 .
Non-excisable
1-0025
23-5S
7-28
0-44
6 .
Non-excisable .
1-027
16-70
11-88
0-41
7 .
Non-excisable
1 -0095
17-17
9-77
0-60
8 .
“ With quinine ”
1-014
15-77
8-26
0-73
9 . .
“ With quinine”
1-080
10-65
24-62
0-607
Though official in the Belgian, Swiss, and Spanish Pharmaco¬
poeias, none of the formula: given in those works is adapted for
producing a wine containing the necessary proportion of alkaloid
for a ‘ ‘ non-excisable ” coca wine. To prepare such from leaves
only, without addition of cocaine, it is necessary to use about
three ounces of leaf to one pint of Avine, Avith the result that an
unnecessarily unpleasant preparation results. It seems better,
therefore, to obtain part of the necessary alkaloid from leaves, and
the remainder by the addition of cocaine, the amount of the latter
required being ascertained by assajnng the wine after maceration
with the leaves. It also seems highly desirable that a preparation
so potent and so widely used as coca wine should be included in
the new Pharmacopoeia.
Pharmacautical Chemists’ and Apothecaries’ Assis¬
tants’ Association of Ireland, Thursday, April 8. — -
Professor Tichborne in the chair. — A lecture entitled
Chemistry, Ancient and Modern.
Avas delivered by Mr. P. Kelly, M.C. P.S.I. — -The chair was
taken at 8.15 p.m. The lecturer said that the ancients believed in
chemistry as the art of making gold, but nowadays people said it
was the science of making money. Analytical chemistry was
described, and its sub-dhision into qualitatHe and quantitative
analysis explained. Matter was defined in its three conditions, solid,
liquid, and gaseous. The seventy elements which go to make up
matter were enumerated and the different gases and solids stated in
detail. Mr. Kelly quoted holy writ in support of his explanation, and
showed that the first verse of the first chapter of Genesis made the
342
PHARMACEUTICAL JOURNAL;
[April 17, 1897.
grand assertion that matter existed from the beginning. The rise
and fall of nations were referred to, and Suidas, a Greek writer
of the 11th century, referred to as an authority for the antiquity
of the word chemistry. The gold, silver, and precious stones of
the Bible were mentioned as showing that the ancients were con¬
versant with chemistry. The metals worked at by Tubal Cain, and
spoken of by Moses, came in for a share of attention. Apothe¬
caries were more thought of by the Israelites than they were to¬
day by the public. Alchemy and alchymists were spoken upon at
considerable length, and their so-called magic described in
amusing terms. The philosopher’s stone was included in the
general description, and the lecturer evoked rounds of laughter by
his humorous sallies in connection. A number of choice photo
slides of chemical celebrities of bygone ages were exhibited by the
aid of limelight, and specimens of the Rontgen rays thrown on the
screen. Some interesting experiments in practical chemistry con¬
cluded the lecture, which occupied two hours in delivery.
— Professor Tichborne spoke at some length on the
merits of the lecture. He gave a meed of praise to the lecturer,
and complimented the Association on having secured the kindly
help of so able an exponent of the science of chemistry.
Some Irish Grievances.
Mr. Kelly complained that chemists in Ireland were ignored. If
one invented a war-like machine for destroying life he would be
created a lord, but the pharmacist whose mission was to heal the
sick was taken no notice of. He thought that Sir Charles Tich¬
borne would not only sound well, but would be a graceful
recognition by the Government of that gentleman’s valuable
services to suffering humanity. Another grievance was the want
of representation by Irish pharmacists upon the committee of
compilation of the new pharmacopoeia. He regarded this as a
national injustice. — Mr. O’Sullivan, alluding to Professor Tich¬
borne, said he was in the front rank of Irish pharmacists and analysts.
He was one of the founders of the Irish Society, and his name
appeared in the Act of Parliament of 1875, through which the
pharmaceutical chemist of to-day lived and moved and had his
being. He urged further ventilation of the question as to why the
Irish Society had no voice in the compilation of the new B.P. It
was unfair that while three or four members of the Pharmaceutical
Society of Great Britain were on the committee, the Irish Society
was left out in the cold. He expressed astonishment that such
men as Professor Tichborne and Messrs. Wells and Kelly allowed the
insult to pass. It was only one more case of “ No Irish need apply.”
PROCEEDINGS UNDER THE PHARMACY ACTS-
A CASE AT NOTTINGHAM.
Illegal Sale of Poison.
Pharmaceutical Society v. Hoolcer.
At the Nottingham County Court on the 12th instant, before his
honour Judge Masterman, the Council of the Pharmaceutical
Society of Great Britain sued Frederick William Hooker (described
in the summons as John Hooper), of 1, Beck Street, Nottingham,
for a penalty for selling poison contrary to the provisions of the
Pharmacy Act, 1868.
Mr. T. R. Grey, instructed by Messrs. Flux, Thompson and Flux,
appeared for the Society ; Mr. W. R. Smith represented
defendant.
Mr. Grey : In this case I appear for the Pharmaceutical Society ,
and in the first place I have to ask for an amendment of defendant’s
name to Frederick William Hooker. When the proceedings were
commenced it was believed that his name was Hooper, but it now
appeared that his name is Frederick William Hooker. I ask to
amend accordingly.
Mr. Smith : You are suing the wrong man. It was Dr. Whit-
greave who sold the poison.
Mr. Grey : We are suing the doctor’s assistant.
Mr. Smith : His name is Frederick William Hooker.
His Honour : I will make the amendment.
Mr. Grey, in opening the case, said that the action was brought
under the provisions of the Pharmacy Act, 1868, to recover a
penalty of £5 for selling poison, and the facts were shortly that
the poison was purchased on November 20 last of the defendant,
who was in charge of the shop kept by Dr. Whitgreave, at 1, Beck
Street, Nottingham. After calling attention to the sections of the
Statute bearing upon the case, counsel further stated that lauda¬
num was the poison sold by defendant. In the Schedule to the
Act opium and all preparations of opium were included, and it
was well known that laudanum was a preparation of opium.
Mr. Smith : I will admit that whatever was sold, whoever it
was sold by, was a poison within the meaning of the Act.
Mr. Grey, continuing, said the printed Register is of itself
evidence, and unless defendant’s name appeared therein it was
evidence that he is not a chemist and druggist. The only case he
would call attention to was the case of the Pharmaceutical Society
v. Wheeldon, which decided that an unqualified assistant selling
poison was liable for penalties.
Arthur Foulds, examined by Mr. Grey : On instructions received
from the Registrar of the Pharmaceutical Society I went on
November 20 to 1, Beck Street. The name over the door was Dr.
Whitgreave. It was 12.45 p.m. when I went into the shop. De¬
fendant was there (witness identified the defendant in court). No
one else was in the shop. I asked defendant for a pennyworth of
peppermint, a pennyworth of aniseed, a pennyworth of paregoric,
and a pennyworth of laudanum. Defendant put the articles together
out of several bottles. A woman came into the shop whilst he was
there. She asked defendant if the doctor was in. Defendant said
no ; he had gone to a case with Dr. Stephenson. The hours he
attended there were from 9 to 1 1 in the morning. Subsequently-
handed bottle over to Mr. Moon.
His Honour : It is admitted that there is a poison.
Cross-examined : I describe myself as an inquiry agent. Knew
that the ingredients made up a cough mixture.
Mr. Smith : I may shorten the case. After the evidence the
witness has given I do not propose carrying the case any further
I do not know if your Honour has power to mitigate the penalty.
After the evidence given by the plaintiffs’ witness that he knew
the articles formed a cough mixture, and consequently led defen¬
dant into a trap, to at least make an order for payment by small
instalments. The doctor had instructed him to say that after the
positive evidence of the witness the defendant could not go into
the witness-box. There was a long interval before the case was
brought before your Honour, and nothing was said to defendant
when the purchase was made, or any part of it left with him.
His Honour : As to reduction of the penalty, I do not think I
have any power.
Mr. Grey : There is no power.
His Honour : The Pharmaceutical Society is not bound to give
any warning. The terms of the Food and Drugs Act are very
different ; that Act defines its own method of procedure. I
cannot say that the Society is to be blamed for the course
taken in this case. The doctor knows well the seriousness of
allowing an unqualified person to sell poison, and in my opinion it
is important that the requirements of this Statute should, for the
safety of the public, be strictly adhered to and its provisions en¬
forced against infringers. I must give judgment for the plaintiffs
for the penalty of £5 with costs.
PARLIAMENTARY NOTES AND NEWS-
Kew Gardens stand in need of improvement, says "the honour¬
able member for Battersea, and on the Estimates on Friday,
April 9, he unflinchingly exposed the “ cussedness ” of the official
staff in not admitting, before the official time for opening, certain
forlorn and disconsolate foreigners and misguided nurse¬
maids who had not taken the trouble to consult the
rules regulating the public use of the gardens. Mr.
Burns wants the public admitted at 10 a.m. instead of 12,
though the raitson d’etre for the alteration was not apparent from
his speech, nor did he explain what was to be done with those
early enthusiasts, British or foreign, who might be led, by their
strong love of botany, to try the gates at 9 a.m. Mr. Chamberlain,
it is satisfactory to know, is quite as much at home in defending Kew
as he is i n cross-examining witnesses before the S outh African Commis¬
sion. He reminded “Honest John” that Kew was primarily a scien¬
tific institution, and its importance from the scientific point of view
could not be disputed. The value of the gardens as a public
pleasure ground was of secondary import. Opening at an earlier
hour would interfere with the work of the officials and materially
affect the scientific value of the institution, and it was not there¬
fore proposed to do any such thing.
Replying to Mr. Yoxall (W. Nottingham), the First Com¬
missioner of Works stated that the daily average of botanical
Apbil 17, 1897.]
PHARMACEUTICAL JOURNAL.
343
students visiting Kew Gardens for study during hours when the
general public was not admitted might be taken at twenty.
Mr. David Howard as a Vice-President of the London Chamber
or Commerce, and having views on the subject of Merchandise
Marks, gave evidence before the Committee now investigating the
operation of the Merchandise Marks Act, 1887. Mr? Howard
stated that he represented the minority of a Committee of the
Chamber of Commerce. The majority was represented by several
witnesses, who complained that the 1887 Act was not protective,
and might just as well be non-existent for what good it was.
I he representative of the minority, however, is inclined
to think the Act a good one, and expressed the
opinion that it would be quite sufficient to mark
foreign goods ‘ ‘ made abroad ” and retain the power which
• already gave of examining goods in transit. He
thought it would be bad to stop such examination, for if that were
clone goods might be falsely marked, sent to London, and re-for¬
warded with every indication that they were of London origin.
On Behalf of the Healthy Oyster Sir W. Priestley has
again urged the head of the Local Government Board to institute
a regular inspection of oyster beds and pits, so that the public
may purcha.se and consume this much-valued article of food with
all their old zest and confidence. Mr. Chaplin responded in a very
sympathetic tone, but felt that the difficulties in the way
were under-estimated. Inspection in this country would not
of itself secure the desired end whilst foreign oysters were
■imported without a clean bill of health. Any scheme would have
to be the subject of legislation if it were to be effective, and Mr.
Chaplin s knowledge of things parliamentary would not apparently
permit him to hold out any sanguine hope of speedy oyster legislation.
Lovers of the bivalve who do not desire to contract disease will
■doubtless find some satisfaction in the official assurance that “ the
subject shall receive careful attention.”
The House stands adjourned till Monday 26th inst. ,at 3 o’clock,
and there will be plenty of work awaiting members then. There
.are twenty-two Government items on the order paper, including
•Supply, and a matter of twenty-five other bills, the promoters of
which may, perhaps, safely prolong their vacation for a few days
beyond Monday week.
Registration appears to be regarded as a panacea for all woes.
JL lumbers, midwives, and persons in charge of boilers are already
the subjects of registration Bills before the present Parliament,
and now Mr. Colville (North-East Lanark) has added to the list
by introducing a very pretentious measure for completing the
organisation of the profession of accountant throughout the
United Kingdom. The Accountants Bill, as it is called, has for
its object the establishment of a professional status for the
-accountant similar to that enjoyed by the legal, medical, and
other professions, and one may be permitted to predict that the
provisions of the Bill, if enacted, will go a considerable way
towards accomplishing that object. In fact the Bill is a very
..stringent one, so much so that it has already been the subject of a
“blocking” motion. It might be pointed out to the promoters that
they have overlooked the existence of the Companies Acts, and
the contingent fact that the use of the word “ person ” in any Act
dealing with personal professional qualifications presents an
■avenue for wholesale evasion of the Act by corporate bodies.
OBITUARY.
Staning. — On March 30, at Hull, William Stalling, Chemist and
Druggist, late of Glasgow. Aged 77. Mr. Staning’s name was
wrongly given as “ Walter ” in last week’s Journal. He was for¬
merly a Member of the Pharmaceutical Society.
Bulcock.- — On April 4, Henry Bulcock, Chemist and Druggist,
Clitheroe. A^ed 76.
Jeffery.. — On April 4, George Jeffery, Chemist and Druggist,
Tring, Herts. Aged 59.
Watts. — On April 6, Robert Watts, Pharmaceutical Chemist,
late of Sheffield. Aged 35. Mr. Watts was a Member of the
Pharmaceutical Society from 1887 to 1895.
Backhouse. — On April 9, William Backhouse, Pharmaceutical
Chemist, Leeds. Aged 69. Mr. Backhouse had been a Member of
the Pharmaceutical Society since 1853.
NOTICES TO CORRESPONDENTS.
All Communications for tha ‘Pharmaceutical Journal' must
be Addressed to the Editor, 17, Bloomsbury Square, London,
W.C., and not In any case to Individuals supposed to
be connected with the Editorial Staff; no responsibility
can be accepted unless this rule be observed. Communica¬
tions for the Current Week’s Journal should reach the
Office not later than Wednesday, but news can be Received
by Telegraph until 4 p.m. on Thursday.
Advertisements and orders for copies of the ‘ Pharmaceutical Journal ’ must
be addressed to the Publishers, 5, Serle Street, Lincoln’s Inn, London, W.C.
Cheques and money orders should be made payable to “ Street Brothers.”
Correspondents should write in ink, on one side of the paper only, and must
authenticate the matter sent with their names and addresses — of course not
necessarily for publication. No notice can be taken of anonymous communications.
Drawings for illustrations should be executed twice the desired size ; clean
sharp lines being drawn with a pen and liquid Chinese ink. Shading by
washes is inadmissible. Photographs can be utilised in certain cases.
Names and Formula should be written with extra care, all systematic names
of plants and animals being underlined, and capital letters used to commence
generic but not specific names.
Queries addressed to the Editor will be replied to in the Journal as early as
possible after receipt, but it is not always possible to publish answers the same
week. See special notice on last page.
Reprints of articles cannot be supplied unless authors communicate with
the Editor before publication of the articles. The right'to reproduce all original
matter and illustrations published in the Journal is strictly reserved.
LETTERS TO THE EDITOR.
The Proposed New Bye-Laws.
Sir, — Allow me emphaticaHy to contradict the suggestion that
the chemists of Glasgow approve of the proposed changes in the
Society’s bye-laws. The proposed change in regard to First exam¬
ination is strongly and generally supported, but that in regard to
the “ Minor ” fee is not less generally condemned. I have not yet
met a Glasgow chemist who does not think it fair that each one
should pay his full share of the cost of registration with the admin¬
istrative work it involves, and were the bye-laws to levy this in a
reasonable manner, I question if there be one here, chemist or
student, who would raise objection. My experience has been that
when pointed out to objectors that the ’68 Act does not empower
the enforcement of a registration fee after passing the “Minor”
examination, while that is regarded as “unfortunate,” approval
would be given to the increased fee were certain other amendments
introduced in conjunction with it. These amendments are not
contemplated in the present proposal, which by itself is not
approved of. The fee is for examination and (life) registration.
How can we, once our attention is drawn to the matter, unblush-
ingly propose that a fee for life registration be paid more than
once ? Yet in the 22nd bye-law this is insisted upon in the case of
persons entering for examination more than one year after a pre¬
vious failure. Nothing could be more unjust. We read into the
work of “maintaining the Register” the administrative work
imposed upon the Society by the Legislature (though not its volun¬
tary schemes), and we say the cost of that work should fall equally
upon all persons registered. Let the registration fee, therefore,
provide for that as the present proposal appears to aim at. With
it, however, and in virtue of it as a matter of right, direct repre¬
sentation must be afforded to persons maintaining this administra¬
tion. Direct representation can only be possessed if the individual
form a unit in the Society. I do not advocate “compulsory
membership.” I do advocate that upon a person paying an
adequate registration fee he be eligible for election as an
Associate of the Society without the necessity of further fee.
Leaders of pharmacy appear to think well of such a state of affairs
could it be brought about, and adoption of these conditions, I am
assured, would sweep away the present very strong opposition in
Glasgow. But it is said that cannot be done without obtaining
additional powers from Parliament. I think that view to be
wrong, and I here publicly challenge any person to show in the
Society’s Charter or in the Pharmacy Acts provisions to prevent
it. It is only required that they “ subscribe to the funds of the
Society in such manner as shall be provided by the regulations
thereof.” Registration fees are subscriptions to the funds of the
Society. Even though it could be successfully maintained that
this could not be done with absolutely no further fee, no one will
344
PHARMACEUTICAL JOURNAL.
[April 17, 1897
say it could not be done were there but a nominal fee upon election.
I congratulate the Council upon its activity, and trust all the
points will receive full consideration by members. Proposals of
greater importance have not been before the chemists of Great
Britain for years.
Glasgow, April 7, 1897. J. Anderson Russell.
*** The above letter appears to be a chapter of contradictions, but in the light of
what was done by the Pharmaceutical Council last week it shows that
Glasgow chemists very fully approve of the proposed alterations. — [Ed., P. /.]
Degrading the Dispenser.
Sir, — It may be interesting to some of your readers to know the
estimate placed on pharmacy by those who are responsible for
drawing out the official sheets as sent round to the secretaries of
the various London hospitals for financial statistics by Hospital
Sunday and Saturday Funds. The following is an excerpt from
sheet
Salaries and Wages.
Official Salaries.— Chaplain, secretary, clerk, matron, registrar,
resident medical and surgical officers, collector.
Servants’ Wages. — Dispenser, housekeeper, nurses, servants,
porter, etc.
The dispenser, from this, would appear in their estimation to be a
mere manual worker on a level with the porter ; but perhaps it is
an attempt to get into line with the Local Government Board, as
more often than otherwise the porter is an old soldier.
London, April 6, 1897. Ad Utrumque Paratus (89/1).
The Proprietary Articles Trade Association.
Sir, — This lengthy correspondence has been for the most part in
favour of the Association, and indeed it is difficult to see the
reason why some should oppose the scheme. Why do we keep
open shop? Are we anxious that a considerable portion of our
business should be done at actual loss? With the majority of
us proprietaries form probably 10 to 15 per cent, of our returns.
This means that the same proportion of business is transacted
at loss of interest on the amount absorbed in stocking these
goods. Therefore it is small wonder if the “ aArerage chemist” sub¬
stitutes — indeed some of the stores are very persistent in pushing
their own Cologne, saline, etc., when the more-advertised articles
are asked for. Some time ago the representative of an old-
established “ proprietary ” called upon me. I pointed to a counter
case wherein were a few Scotts’, Geraudel’s, Prog, and other pro¬
tected goods, also to a column of Vinolia soap and a box or two of
Elliman’s on the floor. But non-listed articles were not readily
seen. My object in writing thus is to give a word of encourage¬
ment to those firms who have taken the trouble to ensure a profit
on their goods. They should be treated with respect by every
retailer and every facility given for the sale of their articles. It is
not a question whether chemists lower their status by stocking
secret remedies. My customers (even of the better class) demand
them, and refusal to supply would result in the loss of other trade.
Northampton, April 12, 1897. John Clower.
Sir, — Will you kindly allow me space for a line or two more in
reply to “ Midlothian’s ” letter in the Pharmaceutical Journal for
April 3 ? He says, “the ultimate success of the P.A.T.A. means
the death of substitution.” He is right — in the main, at all events.
There always will be a certain small proportion of irreconcilable
substitutors, but the main body of them (as I have ascertained by
personal inquiry in hundreds of cases) are ready and willing
to give advertised articles a free pass over their
counters when such articles are put on the protected
list. The custom appears to be to hand over the pro¬
tected article when it is asked for— unless the customer asks the
retailer’s opinion, in which case he is guided by the quality of the
article or the nature of the ailment. The leading feature of the
Association’s plan as regards substitution is the absence of com¬
pulsion, whereby sufficient scope is allowed for the exercise of
individual discretion. The almost universal result has been
voluntary goodwill and ready acquiescence in such a rational
arrangement. It is an arrangement under which there is still room
enough left for the exercise of “gumption and tact.” I know
of no one in the P.A.T.A. who has suggested that chemists should
discontinue the use of printer’s ink, or that they should no longer
exhibit their own preparations, or that they should cease to
employ their technical knowledge in preparing and recommending
the same. What we advocate is fair trade all round. I have no
time to dissect * ‘ Midlothian’s ” letter section by section — easy
though that would be. His dictum, however, that the word
“wile” can have no other than a bad meaning is sufficiently
interesting to claim a finishing sentence or two. It is only one
more instance of the well-known fact that language conveys a
different meaning to different minds. According to Johnston’s
Dictionary (unpublished edition ! !), which for present purposes I
prefer to the big volume used by “ Midlothian,” the word may be
used in either a worthy or unworthy sense, just as the context may
indicate. An instance of the former occurs in Burns’. I quote
from memory
“ To court Dame Fortune’s fickle smile
Assiduous wait up her
In every way, by every wile
That’s justified by honour.”
My wife called my attention only this week to another example
in the Daily Mail, in which “loving ways and winsome wiles ” are
referred to with a meaning the reverse of invidious. If I mistake
not, the idea of honourable wiliness is contained in the injunction
in a certain good old Book : “Be wise as serpents and harmless a&
doves.” Does not the same Book tell us that “ the serpent is the
most subtle (wily) of all the beasts of the field ? ” I am not a D.D. ;
therefore I am open to correction on that point. In any case,
“Midlothian” is such a very superior person, I expect he will
claim that his code of ethics is above these authorities.
Brixton, April 9. William Johnston.
Sir, — Your correspondence columns show at the present time a
fair diversity of opinion on the topics at present occupying the
pharmaceutical mind. I note that there are many who have
not yet mastered that “huge joke” the P.A.T.A. Even
“Catalysis” appears to take it seriously. Mr. Glyn- Jones has
made it easier than ever for some of us to “place our own goods,
but at present the “list” is comparatively insignificant. It is sur¬
prising, however, to find some makers so readily “taken in,” induced,
so to speak, to imagine that chemists will ever sell their goods with
any pleasure or at any time, if it be possible to avoid doing so. Mr.
Ray suggests as a remedy for “ cutting ” the raising of the standard
of the Preliminary examination ! Mr. Ray is thinking possibly of the
years 1915 and beyond. But it is wise to look well ahead. The
result of raising the standards all round will be doubtless a rather
higher social standard of men who will naturally expect better
pay. If I venture to prophesy at all it is that qualified and un¬
qualified will be scarce and somewhat expensive. The bringing in of
a better class (socially) of youths probably means also more capital,,
without which “cutting” is seldom successful. The new and
educated and better equipped contingent, being the sons of suc¬
cessful business men, will no doubt, “ make things hum” generally
— there can be no guarantee the other way. To prophesy again,
the better conducted stores and company pharmacies have come
to stay. If there be any serious opposition to them at all, any-
snuffing out, it will take the form of other company pharmacies-
under historic names probably. The Society has already raised
the standard considerably all round, and what is the tendency ?
For an answer to this, read the Journal and its contemporaries for
a single week. We are submerged amidst a colossal pile of
“patent medicines” and ready-made stuff ; dispensaries abound
and thrive, doctors dispense more than ever they did, i.e., where
they do not get enough of “free samples” to save dispensing?
Sick clubs, with all sorts of alluring side shows, all help to take
the practice of pharmacy from the druggist. Some of our
qualified men see their last of what should be their profes¬
sion in the examination room. The standard is higher certainly
in 1897, but the poison schedule is still practically that of 1867.
Finally we are constantly blaming outsiders for some of our
troubles, but for my part I do not forget that the most unreason¬
able and indiscriminate cutter to be found in the country is a
chemist on the Register, while as to “company” pharmacy this-
existed before the advent of Boots, Limited.
April 3, 1897. A. J. R. (87, 40).
Ferri et Qttininje Citras and Potassii Citras.
Sir, — I cannot agree with the conclusion arrived at by the
members of the Liverpool Pharmaceutical Students’ Society regard¬
ing the best method of dispensing mixtures containing pot. citras
and ferri et quin, cit., as reported in your issue of 10th inst. If
dispensed as Messrs. Wokes and Lean suggest, the result will be
a slow deposit of crystals upon the sides of the bottle while in the
April 17, 1897]
PHARMACEUTICAL JOURNAL.
345
customer’s possession. The addition of citric acid somewhat retards
the formation of the precipitate, but the crystals then
separate in magnificent rosettes, the size increasing
with the proportion of citric acid added. My atten¬
tion was drawn to this reaction about two years ago, and
I then performed a series of experiments, using neutral and acid
pot. cit. with a view of ascertaining whether or not the precipitate
could be avoided, but in all cases it occurred sooner or later. The
best mode of procedure seems- to be to mix rather concentrated
solutions of both salts, so as to get down as much precipitate as
possible, add the remaining ingredients, if any, and attach a
“ Shake the bottle ” label. Made thus the mixture is not elegant,
but the increased accuracy of dosage more than compensates for
any fault in its appearance.
Uchfield, April 12, 1897. W. G. Stratton.
The Dose of Tincture of Strophanthus.
Sir, — Three or four years ago I had a customer (a gentleman about
seventy years of age) who took 50 min. of tinct. strophanth. three
times daily or oftener for three or four days in succession, without
any apparent ill-effect. His doctor prescribed for him tr.
strophanth., §i. m. x. t. d. s. He was supplied with one of Maw’s 60
minim glass measures with twelve graduations — 5 to 60 minims — the
lines extending on both sides of the upright mark. I do not know
liow long that ounce lasted him, but when it was finished he came
for a double quantity and I supplied him with a 2 oz. bottle. To
my surprise three- or four days afterwards he brought the
•empty bottle and requested a further supply. I asked him
what had become of the two ounces he had shortly before, and
he replied that he had taken it all. “But,” I said, “you surely can¬
not have done so, for you were only to take 10 minims three times
a day.” “Well,” he said, “ so I did, and measured it carefully,”
and showed me how he had measured it. He had actually cpunted
ten of the lines on the side where the figures did not appefir, and
believed that each of those marks represented a minim, so that he had
taken 50 minims for each dose instead of 10. Anyhow, he had taken
the two ounces in three or four days, and did not appear any the worse
for it. There was no question about the character of the tincture,
as it was tr. strophanth. virid, obtained direct from Duncan and
Flockhart. From this and the experience related by Mr. MacNaught
it would seem that tr. strophanthus is not so poisonous as generally
represented.
Cheetham Hill, April 10, 1897. W. Wilkinson.
Sir, — The letter from Greenock in your issue of 10th inst.
referring to “Tinct. Strophan.,” is something more than “a
surprise,” not only with respect to the very large dose taken,
but to the fact of such a medicine being prescribed in so concen¬
trated a form. Such prescribing is as dangerous as it is unwise,
and that more fatalities do not occur surprises me.
Sale, April 13, 1897. A. Smith.
An Assistants' Qualification Wanted.
Sir, — During the past year or eighteen months several of my
assistants have gone up for their Minor examination in Edinburgh,
and a large percentage of them have unfortunately got “ploughed.”
As they were all reliable young men, exceedingly well up in
practical every-day dispensing and the routine work of the
pharmacy, and as I knew they had faithfully and systematically
devoted their attention to their studies, many of them for con¬
siderable periods, I was somewhat surprised at the heavy mortality.
On making inquiry of the candidates I learned that they mostly
failed in two subjects, and that the failures were due to the
examiners taking them into regions quite unknown to them and
entirely beyond the scope of pharmacy. I know absolutely nothing
of the abilities and fitness of the examiners on these two subjects,
Iwrite therefore without prejudice, I suppose, and doubt not that they
are good men and true ; but, if my information is correct, the candi¬
dates were presented with objects for detection, estimation, and
classification which had not the slightest bearing on pharmacy as
it a£ present exists. I think the majority of my professional
brethren will indorse my opinion that we would much prefer our
qualified assistants to have a thorough practical knowledge of
chemistry, botany, and materia medica as they exist in the
Pharmacopoeia (and I would even go the length of suggesting that
the questions for the Minor examinations should be entirely found
within the boards of that volume) instead of confusing candidates
with salts of tin and aluminium, which are only known as chemical
curiosities, or presenting them with specimens of flowers and
plants which are never seen except in a conservatory, and which
are put to no use in medicine. Let the examinations in all the
subjects be as stiff and searching as the examiners choose, but let
the questions have a distinct bearing on the business in which can¬
didates are eventually to earn their bread and butter. The Phar¬
maceutical Society and the examiners thereof should bear in
mind that it is possible to “ sour ” the young men who are coming
forward. It is all very well to raise the status of pharmacy, but it
is also possible to kill it with over-elevation.
Again, if there is any truth in the repeated statements that the
Society is financially dependent on the fees arising from the exami¬
nations, then I think there is the further danger of assistants
banding themselves together, refraining from presenting them¬
selves for two or three years, and thus placing the Society in grave
pecuniary difficulties. I have no sympathy with the proposed
new bye-law increasing the entrance fee for the Minor to
£10 10 6'. I do not feel myself qualified or in a position
to argue the pros and cons of' the proposed change ; but this
harassing of the goose which supplies the golden eggs is, in my
humble opinion, not conducive to the best interests of the Pharma¬
ceutical Society. If it is absolutely necessary, however, to raise
more money for the upkeep of the Society, there is, I think, a way
to attain this object, and by a method which has many favourable
points to recommend it. On a recent occasion an esteemed friend
and thorough practical pharmacist — -Mr. Charles Kerr of Dundee
— suggested to me that it might be wise for the Pharmaceutical
Society to obtain powers to have an assistant’s qualification. The
idea is, I think, a capital one. A modified Minor examination
might be arranged, qualifying an assistant to handle and retail,
under a qualified proprietor, all the scheduled poisons, but not en¬
titling him to start business on his own account, nor super¬
intend a branch shop, nor act as an assistant under a
limited company, the shareholders of which are not qualified
chemists and druggists. Employers willing and anxious
to carry out the provisions of the Pharmacy Act as it is now
interpreted would find in this qualification a great convenience for
obtaining reliable assistants ; and to many assistants ir would
prove a decided boon and be of great advantage. Retaining the
Preliminary fee at £2 2s. with an assistant’s fee at £3 3s. and a
further fee of £5 5s., combined with an examination something
more stiff than the “Modified Minor” suggested above, butlesssevere
than the present Major, qualifying an assistant to start business on
his own account, would bring in the necessary funds to the Society’s
exchequer and would safeguard the highest interests of our business.
I Have no personal object to gain, or interests to serve in asking
the insertion of the above suggestions in your valued Journal. I
happen to require a somewhat large staff of assistants, and am in
a position to see the difficulties which present themselves to both
employer and employes in the earnest endeavour to carry out
faithfully and honestly the provisions and requirements of the
Pharmacy Act.
Glasgow, April 12, 1897. John McMillan.
The Approaching Council Election.
Sir, — Will you allow me space for a few words in support of the ap¬
peal made by Messrs. Gostling and Keen, that an addition should be
made to the number of London members of Council at the coming
election ? An ideal Council, like an ideal Parliament, is one which
represents in due proportion the interests and opinions of its con¬
stituents. This the Council of our Society can scarcely be
said to do at present. While at one time London was
over-represented, it will be admitted that, with only
five representatives out of twenty-one, it is now under¬
represented, if we consider its size, importance, and special
interests. In addition to this the Council has a grind¬
ing amount of routine and administrative work to do, which
can only be done promptly by local members, and it therefore
appears desirable, if not necessary, for the interests of the
Society that a quorum of the Council (seven) should be readily
available. For these reasons I join with Messrs. Gostling and
Keen in their appeal for support being given in the coming election
to the London candidates, and would more especially urge the
consideration of these reasons upon my friends in the North.
Kirkcaldy, April 13, 1897. David Storrar.
346
PHARMACEUTICAL JOURNAL.
[April 17, 1897.
ANSWERS TO QUERIES.
Special Notice. — Scientific, technical, legal and general information required
ley readers of the ‘Pharmaceutical Journal’ will he furnished by the Editor as far
as practicable, but he cannot undertake to reply by post. All communications must be
addressed “Editor, 17, Bloomsbury Square, London, W.C.,” and must also be authen'
Heated by the names and addresses of senders. Questions on different subjects should
be written on separate slips of paper, each of which must bear the sender’s initials or
pseudonym. Replies will, in all cases, be referred to such initials or pseudonyms,
and the registered number added in each instance should be quoted in any subsequent
communication on the same subject.
Plants Identified. — They are Saxifraga tridactylites and Dr aba
verna. [ Reply to R. D. — 89/29.]
Boards of Examiners. — The boards of examiners meet next in
July. [ Reply to G. H. H. — 89/2.]
British Pharmacopoeia. — It may be published towards the end
of the year, and the metric system will probably be introduced
as an alternative system. [ Reply to G. H. H. — 89/2.]
Removal of Terpenes from Essential Oils. — This is done by
careful fractional distillation, in some cases under reduced
atmospheric pressure. [Reply to Verax. — 88/28.]
Mosses Identified. — 1, Polytrichum commune ; 2, Hypnum
schreben ; 3, Bryum inclinatum ; 4, No specimen with this number ;
5, Ceratoda purpureus ; 6, Tortula muralis. [Reply to R. S. — 88/37.]
Powder for Worms in Poultry. — The powder you send is
nothing but a mixture of carbonates of calcium and magnesium/
tinted with a trace of ferric oxide. It is difficult to see how this
can do the fowls any good, but it has the merit that it can do them
no harm. [Reply to “Correspondent.” — 88/27.]
Preparers of Microscopic Objects. — Good work is turned out
by Mr. Ernest Hinton, 12, Vorley Road, Upper Holloway, Lon¬
don, N. ; Mr. Geo. T. Phillips, Rosneath, Crown Hill, Upper
Norwood, S.E. ; and Mr. Abraham Flatters, 16, Church Road,
Longsight, Manchester. [Reply to H. W. S. — 88/32.]
White Embrocation. — The following gives a good white per¬
manent emulsion. Two eggs, white and yolks ; oil of turpentine,
9 fluid ounces ; acetic acid, 5 fluid ounces ; water, 7 fluid ounces.
Rub the eggs smooth with the turpentine, gradually add the
water and finally the acetic acid. [Reply to W. J. W. — 87/39.]
Purification of Paraffin Oil. — Digestion with animal char¬
coal will partially remove the odour of paraffin ; the most effectual
method is to “cover” the smell with a little citronella or some
other strong-smelling essential oil. It is not possible to remove the
fluorescence by any simple process. [Reply to Verax. — 88/28.]
Surfeit Water for Horses. — Potassium nitrate, 2 drachms ;
tartarated antimony, 30 grains ; spirit of nitrous ether, 1 fluid
ounce; water, to 10 fluid ounces. “Potato Drops” we do not
know. Can the name be a corruption of “Bateman’s Drops”?
As to “ Green Mallet,” it is difficult to suggest what that can
possibly represent. [Reply to Lyra. — 87/14.]
Plants Identified. — So far as could be determined your box
contained specimens of Petroselinumsegetum, Nepeta cataria, Salvia,
verbenaca, Mnium ligulatum, and Hypnum purum, but please note
that we cannot undertake to name plants not in flower. The
labels were detached, so we cannot give the numbers. Adoxa is
rather local but not rare. [Reply to L. A. R. — 88/19.]
Brewing Beer and Stout. — We cannot in this column, nor
indeed if we were to devote the whole Journal to the subject could
we give you full details as to “manufacture of the different beers
and stouts.” You will get much information from Pooley on
‘Brewing,’ and from the ‘Brewer, Distiller and Wine Manufacturer,’
one of Churchill’s technological handbooks, or the second and
revised edition of V right’s ‘ Handy Book for Brewers,’ just pub-
ished (Crosby Lockwood, 12s. 6 d.), may serve your purpose.
[Reply to J. W.— 88/21.]
Mist. Ferri Perchloridi, B. S. H. — Take of solution of per-
chloride of iron, B.P. , 15 minims; sulphate of magnesia, 15 grains i
distilled water, 1 fluid ounce. [Reply to J. E. D. — 89/32.]
Mist. Arsenicalis, B. S. H. — Take of arsenical solution, B.P. , 5
minims ; distilled water, 1 fluid ounce. [Reply to J. E. D. — 89/32. J
Dispensing Resinous Tinctures. — Yes, it is perfectly legiti¬
mate to employ a little mucilage to suspend resinous bodies when
dispensing such tinctures as tinct. cannabis ind. In fact, it is bad
pharmacy not to do so, for it is the only way to produce a decent
mixture, and at the same time to ensure that the patient will on
every occasion take a uniform dose. [Reply to Qu.esto. — 87/16.]
To Prevent Tins from Rusting through Labels.— Probably
if you first apply a coat of shellac or some other varnish to the tin
and then use good gum mucilage to fasten the label on, you will not
be troubled with rusting. The gum will adhere to the varnished
metal surface. The preparation you name is not always neutral,
and probably starts oxidation of the “ tin ” and so causes rusting.
[Reply to F. W. J. — 88/4.]
Spirit Gum for Theatricals. — We have found the following
answer very well for fixing on false moustaches, eyebrows, etc.„
for theatricals, but we cannot say if it is what is used in the pro¬
fession : — Mastic, 1 ; hard tolu, 2 ; methylated spirit, 6 fluid
parts ; methylated ether, 2 fluid parts. Dissolve and decant.
Moisten the article with some of this and press firmly on to the skin
for a few seconds. [Reply to W. R. F. — 87/36.]
Dispensing Query. — In the mixture cocainse hydrochlor. , j) i.
boracis, gr. x. ; vinum opii, itlxx. ; aquas, ad. gij., the borax
precipitates the cocaine. This is a piece of bad prescribing. The
difficulty may be met by adding five or six drops of dilute hydro¬
chloric acid to the mixture before adding the borax. This will
prevent the formation of the alkaloidTal precipitate. If, however,
the drops are to be used for the eye, this course might not be
appropriate. In that case the attention of the prescriber should,
be called to the incompatibility. [Reply to F. W. D. — 88/25.]
Lin. Terebinthinje B.P. — Using the proportions in the official
formula, a thick cream will be produced, rather more fluid than
lin. potass, iodid. c. sapone. In reply to criticisms on this formula,
the late Professor Redwood, who devised it, finally defined it
somewhat ambiguously as a “thick permanent emulsion” (vide.
Ph. J. [3], xvii., p. 742). The same volume- also contains much
correspondence on the subject. A far more satisfactory article is
obtained by doubling the quantity of water in the official
formula ; this gives a good liquid emulsion. So marked is the
difference, that the two forms are prepared in the wholesale trade,
the demand for the fluid preparation being more than four times
greater than that for the thick variety. [Reply to Quassto. — 87/16.].
Composition for Graph. — Sheet gelatin, 3 ; water, 12; glycerin r
18 ; lead carbonate, If. Soak the gelatin in the water until quite
soft, then dissolve with heat in the glycerin, add the lead car¬
bonate, and stir until smooth. Pour into the frames and remove
any air bubbles on the surface by drawing over them the edge of a
sheet of notepaper. The ink for the above may be made from
soluble “aniline” dye, 1; methylated spirit, 1; water, 5.
[Reply to “Graph.” — 89/12.]
ANONYMOUS COMMUNICATIONS.
Servus. — We cannot publish any letter not authenticated by
the writer’s name and address.
E. A. W. — You have omitted to furnish your name. Read the
special notice at head of this page.
COMMUNICATIONS, LETTERS, etc., have been received from
Messrs. Bacon, Baron, Bennett, Caldecott, Cheers, Clement, Glower, Cresswell,
Crofts, Currie, Daniel, Davy, Elkington, Griffiths, Haigh, Hallaway, Hoare;
Hopley, luce, Johnston, Mackie, McMillan, Marshall, Miller, Moss, Murray,
Palmer, Peck, Ridlington, Robinson, Bussell, Sandell Co., Smith, Squire-,
Staning, Storrar, Stratton, Wendon, Whigham, Wilkinson.
\
April 24, 1897.]
PHARMACEUTICAL JOURNAL.
347
THE CULTIVATION OF SUMBUL IN ENGLAND.
BY E. M. HOLMES, F.L.S.
The sumbqi root of commerce has of late years been of very
inferior quality compared with the fragrant root imported twenty-
five years-ago or more, and usually consists of smaller and more
cylindrical pieces, with only a very faint musky odour. The
structure is also much firmer, and the resinous parts are usually
blackish and dirty, in strong contrast to the paler non-resinous
portions. The upper or rootstock portion, which is marked with
rings like the true sumbul, is evidently often branched, which I
have never seen in the true sumbul, in which the upper portion
usually tapers to a rounded fibrous apex.
The sumbul of the present day is therefore probably derived
from a different plant with a more cylindrical root, branched near
bulbs. The fleshy roots at that period of the year appear to lose
all the small rootlets, and will then bear digging up and trans¬
planting without injury, the tuberous root sending out, in the
following early spring, new rootlets.
In February, or in late winters in March, as soon as the ground
is no longer hard from continued frost, the sumbul plant sends up
one or more young leaves. These may be a little injured if exposed
to hard frost, although not injured by white frost, but as a rule
new leaves come on and the plant stands our winters as well as
most indigenous plants of the same natural order. The fully
developed leaves appear in April, and continue to grow until
July, when they turn yellowish and gradually wither. The
root increases in size every year, retaining its oval form pre¬
sumably until it attains a sufficient reserve of nutrition to enable
Ferula Sumbul. — Root grown at Sevenoaks, Kent, together with portion of leaf and flower. (All one-ninth nat. size.)
the apex, and having a firmer substance. It was suggested some
years ago by Dr. J. E. Aitchison (Trans. Linn. Soc., ser. ii.,
Bot., p. 69, pi. 20-21) that it might possibly be derived from
Ferula suaveolens, which has only a faint musky odour. He states
that the root is scented, and is one of the kinds of sumbul
exported from Persia to Bombay by the Persian Gulf (l.c., p. 69).
It seems to be desirable, therefore, that the true sumbul should
be cultivated to meet a trade desideratum. The use of an inferior
drug will otherwise probably lead in time to the entire disuse of
the drug. Under these circumstances my own experience in the
cultivation of the true sumbul plant may prove interesting to some
of the readers of the Pharmaceutical Journal.
Some years since one of our corresponding members, M. Andrew
Ferrein, of Moscow, sent me some young plants of Ferula
fcetidissima, and with them two young plants of F. sumbul. They
arrived in autumn packed in husks of buckwheat like ordinary
Vol. LVTLL (Fourth Series, Yol. IV.). No. 1400.
it to throw up a large fruiting stem. The inflorescence of the
specimen that flowered in the Kew Gardens some years ago
attained a height of about eight feet, and the plant then died.
To secure the healthy growth of the plant, it is
necessary to give it plenty of water, and a little weak
manure water, during the growing season from April to J uly. A
mulch of well-rotted manure around the plant in the autumn,
taking care to protect the crown by a covering of clean sand, also
helps its growth. My plants, which are now about six years old,
have not flowered, but the root of one which I took up a few days
ago for transplanting, measured about 6 inches long by 3| broad,
and had a strong persistent musky odour where injured, exuding
abundance of white milky juice. The roots are somewhat twisted,
and spread nearly horizontally below the ground. It is obvious
from the shape that such a root might furnish two tapering and
one cylindrical sections of the thickness of the old-fashioned, but
348
PHARMACEUTICAL JOURNAL.
' [April 24, 1897
that it could not furnish the cylindrical pieces two or three inches
long of small diameter that occur in the drug of the present day.
Provided that good seed could be obtained, there is little doubt
that sumbul might be cultivated in temperate or mountainous
districts in the colonies, or in ordinary gardens or fields in this
country without any difficulty.
The chief difficulty in obtaining good seed is due to the fact
that in this country the fruit are apt to be ruptured by the rains.
In their native country the fruits are produced in the hot weather.
In this country, therefore, it is necessary to protect the ripening
fruits from rain.
SIR SAMUEL GARTH, M.D.
In the year 1693 Samuel Garth, at the age of 32, was elected a
Eellow of the Royal College of Physicians and entered on a medical
career in London, equipped with the flowing wig and gold-headed
cane, which then and for long afterwards were affected by the
Faculty. He was versed in all the medical lore, such as it was,
of the time, and was, moreover, an accomplished scholar, and one
of the pleasantest and most genial of companions. A Yorkshire-
man by birth, he had taken his degree of M.D. at Cambridge after
studying physic at Leyden, and was to become the author of far
the best English poem ever suggested by a medical theme, the
once famous and still readable “ Dispensary.” To add to his other
qualifications for making his way in the world, he was a zealous
Whig at a time when under William the Deliverer Whiggism was
very much in the ascendant.
Garth’s gifts and merits were quickly appreciated by his
colleagues. The year after his admission to the College he was
appointed to deliver the Gulstonian lectures, and two years later
the Harveian oration itself. This last is a piece of vigorous
rhetorical Latin, containing a glowing panegyric on William III.,
which may have commended it to the great man to whom it was
dedicated — Charles Montague, afterwards Earl of Halifax, then
William’s First Lord of the Treasury. Montague himself was a
wit and a poet, and always a patron, after a fashion, of wits and
poets ; the original, in a measure, of Pope’s Bubo.
Fed with soft dedication all day long.
More germane to the occasion was a eulogium on Harvey and the
men of light and leading among the English physicians, his
successors, and by way of contrast a scathing invective against the
medical quacks with whom London abounded. Still more significant
was the peroration in which indignant reference was made to
certain enemies of the College who wished to destroy its authority,
and whose machinations, sad to relate, Garth mournfully hinted,
were aided by allies in the august conclave, which he addressed.
It was by the machinations of these enemies of the College without,
and their aiders and abettors within, that Garth was to be led to
write “ The Dispensary ” and become of all the physicians then in
London the one most talked of, not only by the “ profession ” but by
“society.” When Garth, in 1697, delivered the Harveian oration,
a crisis had been reached in that long and bitter contest between
the College of Physicians and the London apothecaries, which was
perhaps the most stirring episode in the history of English medicine
during the eighteenth century. It was a struggle on the part of
the College to strengthen its waning authority over the apothecaries,
and on the part of the apothecaries to preserve what had become
a practical equality with, and in some respects, a virtual ascendancy
of, successful tradesmen over those haughty M.D.’s, proud of their
degrees, their wigs and gold headed-canes. Legality was at issue
with fact, privilege with the possession which is nine points of the
law.
Long after Henry VIII. had established the College of Physicians
and given its members a monopoly of medical practice in London and
its suburbs, the apothecaries had no separate corporate existence, and
were an adjunct of the grocers, who were originally the sole vendors of
drugs. Even when under James I. the apothecaries were disso¬
ciated from the grocers and formed into a company by themselves,
they remained strictly subordinate to the College of Physicians.
They were not allowed to dispense, much less to administer
medicine, without a physician’s prescription. Nay, the College
of Physicians could order its delegates to enter their premises,
inspect the contents, and destroy any drugs deemed noxious either
in themselves or as having become so by the lapse of time. Great
physicians like Sir Hans Sloane and Dr. Meade even encroached
on the province of the apothecaries, and procured to be vended
specifics of their own invention which were recommended to the
public by the authority attached to their names.
But as time wore on the apothecaries were more and more
resorted to, by the middle class especially, and by the lower class
altogether, for the treatment of ordinary and familiar complaints.
Indeed, in a low state of the medical art, the apothecaries were
quite as trustworthy as ordinary physicians. For most com¬
plaints certain medicines had come to be considered remedies,
and unlike the physician, the apothecary charged no fee for
prescribing. The apothecary became in fact very much what the
“ general practitioner” is to-day, and if there was no examination
to test his competency, he had to serve a long apprenticeship,
eight years, and was subject to the jurisdiction and supervision
of the company. If a physician was called in it was often the
apothecary who recommended him, and as in the last century,
barristers were said to “ hug” attorneys, so young and struggling
physicians “hugged” apothecaries. On the other hand, a physi¬
cian in established practice had a favourite apothecary to whom
his prescriptions were sent to be made up, and the apothecary
thus favoured by Garth’s contemporary, Dr. Radcliffe, died worth
£50,000.
For the College of Physicians to prosecute the apothecaries who
dispensed drugs otherwise than as prescribed by a physician would
have been a troublesome and costly proceeding. In 1687, when
Garth was studying medicine at Leyden, the College hit upon a
plan which they doubtless thought very ingenious, and which
wore a philanthropic look, in order to make at least one class of the
community eager for the prescriptions which other classes were
too often content to do without. They offered to prescribe
gratuitously for the poor of London whenever a certificate of
poverty was produced from the incumbent of a parish. Of course
the supposed boon was neglected. After taking the trouble to
apply for a certificate, the successful applicant would have to pay
the apothecary for making up the prescription, and perhaps the
resentful apothecaries threatened to charge more than if the poor
patient came to them for advice and medicine without a prescrip¬
tion. This scheme having failed, in a year’s time another and
bolder one was proposed. This was that the College itself should
compound the drugs and offer to dispense them at a very
moderate price. But the scheme not only roused the ire of the
apothecaries, who threatened to cease recommending any
physician approving of it, but it was opposed by a small though
powerful minority in the College itself. The opposition of both
kinds was strenuous, and the Lord Mayor and civic authorities who
at first approved it grew luke-warm in their support of it.
Ultimately the second scheme was dropped, and no more was
heard for six years of any other for the humiliation of the
apothecaries.
In 1694, the year after Garth became a Fellow of the College,
another and third scheme, which aimed at a certain co-operation
April 24, 1897]
PHARMACEUTICAL JOURNAL.
349
on the part of the apothecaries, was framed by the College and did
receive the cordial support of the Lord Mayor and the civic
authorities. London was to be mapped out into districts. In
each of them the physicians were to fix the price of drugs with
the assent of the Warden of the Apothecaries’ Company, and a
number of apothecaries agreed to sell them at the price thus
to be fixed on. Again, the Apothecaries’ Company was up in
arms, and threatened to expel as traitors to their order their
consenting members. This scheme, too, collapsed. Once more
the College resolved to open a dispensary of their own, and by a
private subscription of the assenting majority, some fifty of them
guaranteeing £10 each, opened it was during the year in which
Garth delivered the Harveian oration.
Garth was one of the keenest supporters of the College Dispen¬
sary. In giving it support he was doubtless influenced by motives
which were partly, at least, philanthropic. All accounts agree in
representing him to have been one of the kindest-hearted of men,
and he may have thought less of the injury he was inflicting on an
industrious body of tradesmen than of the apparent boon to the
invalid poor. To the goodness of his heart there is other testimony
than that of the wits with whom he then and afterwards con¬
sorted. Among the Sloane MSS. in the British Museum are several
little hasty notes of his to his friend Sir Hans Sloane, asking
for his influence to procure some poor man or woman admission to
an hospital. Here is one of them : “Dear Sir Hans, — If you can
recommend this miserable slut to be fluxed you’ll do an act of
charity for, Dear Sir, Your obedient servant, Samuel Garth.”
The College Dispensary had been open a year or two and was
doing its work better or worse, when there occurred an incident
which prompted Garth to produce— it was published in 1699, and
at first anonymously — his mock-heroic poem, “ The Dispensary,”
turning on the controversy between the majority in the College on
the one hand, and on the minority with the London Apothecaries on
the other. Referring in one of his prefaces — his authorship of the
poem was soon avowed — to a ludicrous description in it of a battle
royal between the two sets of controversialists, he represented it
as “grounded upon a feud that happened in the dispensary be¬
twixt a member of the College and his retinue and some of the
servants that attended there to dispense the medicines, and it is
so far real, though the poetical relation bo fictitious.” One would
like to have had the details of the “ feud,” in which, perhaps, there
was a display of physical force on both sides, but here is the mock
description of the combat between the majority of the College and
the minority, the small number of the latter being reinforced by a
swarm of angry apothecaries. The passage gives a fair notion of
Garth’s general treatment of his theme : —
And now the signal summons to the fray ;
Mock falchions flash, and paltry ensigns play.
Their patron god his silver bow-strings twangs ;
Tough harness rustles and bold armour clangs.
The piercing caustics ply their spiteful power ;
Emetics ranch, and keen cathartics scour.
The deadly drugs in double doses fly,
And pestles peal a martial symphony.
N ow from their levelled syringes they pour
The liquid volley of a missive shower ;
Not storms of sleet, which o’er the Baltic drive,
Pushed on by northern gusts, such horror give.
Like spouts in southern seas the deluge broke,
And numbers sunk beneath the impetuous stroke.
And now the staggering braves, led by despair,
Advance, and to return the charge prepare.
Each seizes for his shield a spacious scale,
And the brass weights fly thick as showers of hail ;
While heaps of warriors welter on the ground,
With galley-pots and broken phials crowned,
While empty jars the din defeat resound.
The various leaders of both parties figure under fictitious names,
which of course did not conceal from “the Profession” the
identity of the originals. “ The Dispensary” was at once success¬
ful, and went through many editions. Nor was this success to be
ascribed solely to the personalities with which it teemed. The sun
of Dryden was setting and the star of Pope had not appeared above
the horizon when Garth’s poem was published. In style and
versification it bridged the interval between the two. The verse
was smoother than Dryden’s, and the point and antithesis seem to
prefigure Pope. There are serious passages, moreover, in “ The
Dispensary ” which are not unworthy of these two masters. Even
now the three last of the following fine lines are often quoted ;
though few, it may be surmised, of those who quote them know
that they come from the almost forgotten “ Dispensary” : — ■
’Tis to the vulgar death too harsh appears ;
The ill we feel is only iu our fears.
To die is landing on some silent shore
Where billows never break nor tempests roar :
Ere well we feel the friendly stroke, ’tis o’er.
To have produced on such a theme a poem which was long con¬
sidered an English classic — it figured in most of the older collec¬
tions of the English poets — is not Garth’s only claim to the remem¬
brance of the profession which he adorned. In connection with a
far more famous poet than he was, the College of Physicians owe to
him the memory of an interesting incident, unique in their annals.
When after Dryden’s death, in 1701, his body was embalmed, at
Garth’s instance it lay in state at the College of Physicians, where
he pronounced a Latin oration over the poet’s remains before they
were borne with great pomp to their final resting-place in West¬
minster Abbey, by the side of Chaucer and Cowley.
Garth’s career thenceforth is one of success, professional and
social. As the author of the much-admired “Dispensary” and
the most agreeable of boon companions, he made friends in high
places, and through them patients flowed in. When the
Kit-Cat Club was formed, soon after the accession of
Queen Anne, Garth became a member, and thus the
associate of great and powerful nobles, among them the Dukes
of Marlborough and Newcastle, and of wits, among them Con¬
greve and Addison. In a letter from Garth to the latter Duke in
the Museum MSS. is an acknowledgment of a fee of 100 guineas.
In his works are printed six sets of verses celebrating the charms
of as many dames of high degree, and written for the toasting
glasses of the Kit-Cat Club. When the Whig Ministry was dis¬
missed in 1710, Garth wrote some lines of indignant sympathy to
Godolphin. They were sharply criticised in the Examiner by a
brother poet, but a Tory, Mat Prior, who had lost a berth when
the Whigs came in and gained one when they went out. Garth
found a defender in no less a person than the great Mr. Addison,
who retorted pretty severely upon Mat in the Whig Examiner.
When “Cato” was performed in 1713, Garth wrote the epilogue
for it. A performance more notable from its probable result was
his Latin dedication a proposed edition of ‘ Lucretius’ to George I.
while still Elector of Hanover. It is fulsome in the extreme, but
no doubt helped when George became King to procure Garth not
only a knighthood but the appointment of Physician in Ordinary
to his Majesty and Physician-General to the Army.
Of all Garth’s contemporaries none loved him and praised him
more than Pope. When the youthful poet’s Pastorals were sub¬
mitted in manuscript to friends, Garth was one of those who highly
approved of them. On publishing them Pope dedicated one of
them, “ Summer,” to Garth, on whose skill in medicine as well as
on his “ bays ” Pope laid stress when referring to the pangs of love,
The sole disease thou canst not cure.
“Well-natured Garth,” Pope calls him in verse, and again —
Garth — the best good Christian he,
Although he knows it not.
350
PHARMACEUTICAL JOURNAL.
[APRIL 24, 1897
This was in reference to the charge of scepticism, to which
Garth was certainly amenable. To him has been ascribed the
reply, which has been fathered on many others when questioned
as to their religion, that “ he was of the religion of wise men,” and
when asked to explain himself further, rejoined that “wise men
kept their own secrets.” In Garth’s case the questioner is said to
have been Addison, and it is also said that when Addison was on
his death-bed Garth sent to ask him “ whether the Christian religion
was true.” Garth was undoubtedly a loose liver as well as a
sceptic, and in the rather imperfect notice of him in the ‘Dictionary
of National Biography’ it is hinted that Dr. Munk, the historian of
the College of Physicians, has in his possession MS. verses of Garth
which it would not be proper to print.
“Call no man happy before he dies.” If happiness could have
been predicated of anyone it would have been of a man of Garth’s
character and career. On the unexceptionable authority of Pope,
however, “ Garth did not take any care of himself in his last illness,
and had talked for three or four years as one tired of life ; in short,
I believe he was willing to let it go.” Just before dying he is
reported to have said to the anxious friends around him, “ Gentle¬
men, I wish the ceremony of death was over,” and so breathed his
last. Pope said of his death that “it wa3 heroical and yet
unaffected enough to have made a saint or philosopher famous.”
If so, he displayed in his last moments the spirit which breathes
in those lines of his on death already quoted. When he died he was
in his 59th year, and left estates in several, counties. Of his various
recorded witticisms, the best was on the legacy left by his contem¬
porary, the then famous and prosperous physician Dr. Radcliffe, to
found the Radcliffe Library at Oxford. Radcliffe was not at all a
reading man, and Garth said that for him to found a library was as
if a eunuch were to found a seraglio !
The college dispensary, the memory of which has been preserved
by Garth’s poem, ceased, in course of time to exist, but precisely
when seems uncertain. Dr. Johnson in his ‘ Life of Garth,’
says of it “ The poor were for a time supplied with medicines, for
how long a time I know not. The medicinal charity, like others,
began well in ardour, but soon remitted, and at last died gradu¬
ally away.” Garth’s latest biographer in the ‘Dictionary of National
Biography,’ speaks of it as “ The first attempt to establish those
out-patient rooms now universal in the large towns of England.”
THE PROPRIETARY ARTICLES TRADE ASSOCIATION
AND LOCAL PHARMACEUTICAL ASSOCIATIONS.
BY W. S. GLYN-JONES.
Very early in its history the Executive of the P.A.T.A. fully
recognised the importance of securing the co-operation of the
various local associations throughout the country.
The cutting evil, in its various forms, and the numerous reme¬
dies proposed, had often formed the subject for discussion at the
meetings of most of the local organisations, and the keenest
interest in the question had been shown. It was, therefore,
reasonable to expect that if the P.A.T.A. could suggest a feasible
plan upon which concerted action might be taken it would receive
the active support of the large majority of the pharmaceutical
associations throughout the land. That these expectations have
been fully realised will be seen from the following brief account of
what has been done in connection with local organisation during
the past year : —
Midland Pharmaceutical Association.— While the P.A.T.A.
was in progress of formation this Association was in the thick of a
discussion of the anti-cutting scheme suggested by Mr. E. J.
Smith, of Birmingham. After hearing what the proposals of the
P.A.T.A. were, they decided to heartily co-operate with us. Their
practical assistance was soon forthcoming, for the draft rules of
the Association were submitted to them for perusal.
and the suggestions forwarded by them to our Council
were much valued, the majority being acted upon. In
April, 1896, the Midland Association decided to call a general
meeting of the trade, with a view of soliciting their
support. The report of the Trade Committee of the Association
was read by Mr. Jones, their Chairman. This report dealt very
fully with the various details connected with the Association. It
recommended the members of the Midland Association to join the
P. A.T.A. ; that the scheme of guaranteed profits should not contain
any system of rebate ; that the question of bonuses given by co¬
operative societies should be considered and dealt with, and that
the members pledge themselves not to distribute hand-bills, nor in
any way assist the sales of any proprietary articles upon which a
profit is not guaranteed, or whose proprietor has not joined the
P.A.T.A. It also advised that the Trade Committee of the
Midland Pharmaceutical Association be permanently appointed.
Mr. Jones, their Chairman, had been nominated as a candidate for
the retail section of the Council of the P.A.T.A., and had been
successful. I would respectfully suggest that the various associa¬
tions throughout the country would do well to imitate Birmingham
in thus forming a special committee of their members to deal with
purely trade matters. The Midland Association has found it work
well. On several occasions matters have been submitted by our
Council to the Birmingham Trade Committee, and they have been
able to afford us considerable assistance.
Bristol Pharmaceutical Association. — It was at Bristol that
the first meeting of the trade was held after the definite formation
of our Association. There was an excellent attendance of the
craft. Chemists * attended from Bath, Weston, Clevedon, and
Swindon, Mr. Allen, the Chairman, referring to it as being a record
attendance. A resolution pledging the meeting to support the
movement was unanimously passed. During a discussion as to the
desirability of forming a local committee to act in connection with
our campaign, Mr. Keen explained that though the local Associa¬
tion was primarily concerned with professional and scientific
matters, there was no reason why the Executive of their Associa¬
tion should not co-operate with the P.A.T.A. A resolution calling
upon the Council of the Bristol Association to act in conjunction
with our Association was unanimously passed. At the annual
meeting of the local association, held a few weeks ago, a resolution
was passed congratulating the P.A.T.A. on its progress, and
urging upon proprietors to add their articles to our list.
Plymouth, Devonport, Stonehouse and District Chemists’
Association. — A week later saw us at Plymouth. No one who
reads the trade press will need to be told that this Association, if
not the most active in the drug trade, is not surpassed by any
other for vigorous action and for the amount of practical work it
accomplishes. Invitations to the meeting were sent out by the
local association to all the chemists in business from Newton
Abbott to Penzance, and there was an excellent attendance. A
resolution supporting the Association was moved by Mr. C. J.
Park, President, and seconded by Mr. R. H. Rendle, the Vice-
President, and after being freely spoken to was unanimously
carried. The meeting asked the Council of the local association to
act as our Executive for Plymouth and the neighbourhood. At
the election of the retail section of our Council the P.D.S. and D.
Association nominated Mr. Cocks as a candidate. He was
returned and has been one of our most valuable members. Matters
affecting the P.A.T.A. are constantly being brought before their
meetings, and as a result of their energy the proportion of our
members to the trade in Plymouth is very high. If all the towns
in the kingdom were as well organised as our friends in Plymouth
the proprietary articles’ difficulty would soon be solved.
Exeter Association of Chemists and Druggists. — On the day
after the Plymouth meeting, the deputation visited Exeter, where
a meeting was held under the auspices of the local Association.
The district around was well represented. Resolutions similar to
those passed at Plymouth were unanimously adopted, and since
the meeting the Council of the Association has acted in conjunc¬
tion with us. Mr. P. F. Rowsell is now our local secretary for
Exeter.
Cambridge Pharmaceutical Association. — Our next visit was
to Cambridge. The meeting here, though not a large one, was of
a very representative character. Mr. A. Sidney Campkin, J.P.,
presided. Resolutions supporting the Association were unanimously
adopted, and at the invitation of the meeting the Council of the
Cambridge Association undertook to help us with our work in the
district. Since then Cambridge has worked splendidly in our
APEIL24, 1897]
PHARMACEUTICAL JOURNAL.
351
interests, and as a result, out of nineteen chemists in the town
seventeen are now members of our Association.
Nottingham and Notts Chemists’ Association. — It was only
to be expected that an anti-cutting association would be welcomed
at Nottingham. The meeting was held in April last year by this Asso¬
ciation. Councillor R. Fitzhugh, J.P., presided, and explained
that it was against the rules of the local association to fix prices,
but that they were met to discuss a question which he thought was
of the greatest importance to them all. The Nottingham chemists
were well versed in the ways of the cutter, and were keenly alive
to the difficulties we had to contend with. A capital discussion
was the result. A resolution supporting the Association was
unanimously passed, and those present joined almost to a man.
We have a number of active supporters in Nottingham, and the
Association has upon several occasions dealt with various ques¬
tions appertaining to our work. Mr. W. Jones was present to
represent the Midland Trade Committee.
Edinburgh District Chemists’ Association.— Early in May a
series of meetings was arranged in the north. The first of these
was held in the Scottish metropolis, where a large number of the
local chemists had been brought together under the auspices of the
Edinburgh Association. A resolution supporting the Association
was unanimously adopted, and the various details of the scheme
received careful attention from those present. The difficulty of
the co-operative stores was one which was keenly felt. It trans¬
pired that die rules of the Association prevented them acting in
conjunction with the P.A.T.A. , but it was decided that a trade
committee of Edinburgh chemists should be appointed. Since
then Mr. David MacLaren has accepted our local secretaryship for
Edinburgh, and Mr. R. MacDougall has agreed to act in a like
capacity for Leith.
Leeds Chemists’ Association. — We were also at Leeds in May,
and there again the local association came to our assistance by
calling a meeting of the trade for us. The chemists and druggists
in the district were well represented, the chair being taken by
Mr. George Ward, the president of the local association. Mr.
Mackay and Mr. Pickard attended on behalf of the Bradford Asso¬
ciation. A resolution supporting the Association was moved by
Mr. Reynolds (Messrs. Reynolds and Branson). This was
unanimously carried, and so was a vote requesting the Council of
the Leeds Association to act as our local executive. Very few
left the meeting without joining.
Bradford and District Chemists’ Association.— On the next
day we were the guests of the Bradford Association. To this
Association must be awarded the palm for bringing together what,
for the size of the town, was the largest meeting we have yet held
in the provinces, over ninety being present. Messrs. Seely,
Pollard, and G. Cobb were present to represent the Halifax Asso¬
ciation. Perhaps the energy of Mr. S. Norman Pickard, the
secretary, was in a large measure accountable for the successful
attendance. Mr. Pickard accompanied me on a tour round the
local chemists, and when I say that he took me into between thirty
and forty shops in the one day, it is evident that it will not be
necessary for him to put in many days of that character to ensure
the success of the Bradford Association. At this meeting resolu¬
tions were unanimously passed supporting our Association, and re¬
questing the local council to act as an executive for the P.A.T.A.
in the neighbourhood.
Halifax and District Chemists’ Association. — On the suc¬
ceeding day we were at the Old Cock Hotel, Halifax. They know
something of cutting at Halifax, but the demon has not succeeded
in crushing out the whole of their conviviality. There were
several features of our vipit there which I am not likely to forget :
the splendid old hall in which the meeting was held, the variety of
the orders addressed to the waiter in attendance, and the conse¬
quent difficulty in getting the meeting well underweigh.
Councillor W. C. Hebden, the President, occupied the chair. This
was of advantage, as he had evidently directed the councils of the
Halifax chemists before, and knew the impossibility of commencing
until a sufficient number of “churchwardens” had made their
appearance. It was a really excellent meeting, and one would
have thought from its character that it was a meeting more to
consider what to do with the surplus profits made during the past
ear than to devise a means by which business could be made just
arely remunerative. Perhaps, after all, the best feature from our
point of view was that not a single man left the room without
leaving the 5 s. subscription to the P.A.T.A. behind him.
(To be continued. )
THE ART OF LITERARY COMPOSITION.*
BY JOSEPH INCE.
( Concluded from page 293. )
The Balance of Words.
Now I want to show the syllabic construction of the English
language, which consciously or unconsciously every writer must
observe, as it lies at the basis of all good composition ; or you may
define it as the rhythmical laws which regulate the musical balance
of the wording of the text. A long or short vowel must be so
placed as not to jar against the rhythmical accentuation of the
phrase.
A writer who from want of ear or from carelessness fails in this
particular, will never write so that his style may please.
It is necessary to understand certain technical terms. By Quan¬
tity is meant a vowel pronounced either long or short ; an accented
syllable in English is held to be a long syllable [-], an unaccented
syllable is short [u]. A long, followed by a short syllable is called
a Trochee [- u] ; if by two short syllables, a Dactyl [- u u]. A short
followed by a long syllable is an Iambus [u -] ; two short, followed
by one long constitute an Anapest [u u -]. These in English should
never jar ; two short syllables should rarely end a phrase, still less,
three.
The genius of the English language will be found to be iambic ;
it is this which gives to poetry its music and to prose its charm.
“The curfew tolls thS knell of parting day.” — [Gray.]
Take Byron’s magnificent lines on the Greek nation : —
“ He who | h&th bent | him o’er | the dead. | ”
There is no finer passage in the range of English poetry : the
whole description is iambic.
Prose is not restricted to lines and sentences of a definite
measured length, but the law of the balance of words is inexor¬
able, of which our highest prose literature forms one long
illustration.
Elsewhere I have dwelt on this point at some length. Take
Isaac Walton’s description of the nightingale which — “breathes
such sweet loud music out of her little instrumental throat that it
might make mankind to think miracles are not ceased.”
Take the mass of Elizabethan literature, and in our own time,
Stevenson, Froude and Ruskin.
To end a paragraph by two insignificant words, as “ of it,” “ by
it,” “to it,” is bad composition, unless “of” or “to” is a com¬
pound part of a verb ; a touch will effect the change.
Dire was its fall — not the fall of it. He set little store by it
— read, by which he set little store. Take this sentence from a late
review : “ (The conception) is one which young students of the
master will do well to fight shy of,” read — “ of which young
students should fight shy. ” It is not even hinted that a master of
style and composition is on the look-out for an iambus or other
quantity. Instinctively his trained ear guides him to the selection
of rightly balanced words which when analysed will be found in
the main to be iambic. A writer, like a musician, will indulge in
infinite variations on the scale, but no discord must be made by the
arrangement of his syllables or notes.
He would be a courageous man indeed who would venture to
give too much advice gratis on the actual wording of an original
contribution ; needless to say, it should be distinctly written ; on
one side only of the paper; corrections to be made in full upon the
copy, and not on the revise ; and nothing to be left to chance.
All this means saving of expense and perhaps annoyance. A clear,
clean copy results in a fair proof and a nearly perfect revise ; terms
to be explained hereafter. Now, look down your copy for
“ repeats,” that is, for remarks twice made, or given twice over
in a slightly different way ; they are no good and only weary.
Carefully look after “ sequence,” namely that one paragraph
naturally follows its predecessor and thus keep all your facts,
illustrations, and main arguments together. Then, may I implore
you to survey your adjectives ; if they are of real value, and they
often are, leave them by all means ; if not, strike them out with
unsparing hand, for here stern self-criticism is best. Like John
Bright and John Wesley, choose when possible short -words— they
are an element of strength.
Never put two adverbial forms together, except “very” as a
superlative; while custom admits the phrase “Very sincerely
yours,” it is not well to say, “ how positively blindly,” or “how
* Read before the School of Pharmacy Students’ Association, March 26, 1897.
352
PHARMACEUTICAL JOURNAL.
[April 24, 1897
particularly foolishly,” or even “how wisely and skilfully he
acted.” Read, “with what positive blindness,” “with what
particular folly,” or “ how wisely and with what skill he acted.”
Good writers uniformly steer clear of this defect, they even select
the adverb which will give the shortest noun, and therefore write,
not “ how skilfully and with what wisdom,” but “how wisely and
with what skill.”
Lastly, shun fine writing.
Hard work, practice and constant observation will do the rest,
for there comes a point at which a writer must be left to his own
instincts and trust to his own resources for the expression of his
ideas.
We near the crisis of a writer’s fate : the manuscript is finished
and committed to the custody of the pillar-post. No matter
whether the article in question be a communication to a periodical
or to a scientific journal, there is one spasm of anxiety which every
writer, living or dead, has experienced in his time — What hopes
and fears centre round that document ! Will it reach its destina¬
tion or will a nefarious postman annex that one particular packet
with fraudulent intent ? Will the editor be in a fit complacent
state of mind to recognise its importance ? or will the sub-editor
glance at its contents, and, ignorant of its value, consign it to the
waste-basket ? Lo ! in due time the maligned government official
brings a long blue envelope which contains the enchanting
message : “ Call at 10.30 prompt.”
He does call, and ecstasy in excelsis ! is presented with a
PROOF. Never again, throughout his whole career can that
writer have a like sensation.
Charles Dickens (I quote from the life by John Forster) “has
described himself dropping his paper stealthily one evening at
twilight with fear and trembling into a dark letter-box in a dark
office up a dark court in Fleet Street ; and he has told his agita¬
tion when it appeared in all the glory of print. ‘ On which occa¬
sion ’ (says Dickens) ‘I walked down to Westminster Hall and
turned into it for half-an-hour, because my eyes were so dimmed
with joy and pride that they could not bear the street, and were
not fit to be seen there.’ ”
To compare great things with small, never shall I forget the
appearance of my own first paper written by request of Mr. Jacob
Bell; it was called “A Student’s Sketch of Orfila.” I imagined
that the whole of Covent Garden Market observed the talented
author as he passed through the central avenue. I now don’t think
they did.
At this stage we come to —
Press Correction.
You have despatched the “ copy ” by which is meant the manu¬
script sent in for printing and you have received a proof, that is
the first issue from the press, for your correction. You will save
the compositor much trouble and yourself vexation, by adopting
the signs to which he is accustomed ; side remarks and instructions
only worry and may get worked into the text, whereat the printer
quotes from the imprecatory psalms ; thick lines are never used,
as they obscure the wording. An excellent leaflet, “ How to
Correct,” is published by Spottiswoode and Co., New Street
Square, London ; also there has been issued a most useful small
pamphlet by the late William Blades, called “ How to correct
Printers’ Proofs,” which will be found a most useful guide. The
price is sixpence, and it may be obtained from Blades, East, and
Blades, 23, Abchurch Lane. The writer says — “ Remember that
corrections should be placed in consecutive order in the margin,
on a level with the line corrected, and that a slanting stroke ( /) should
be put after each correction ; it serves to draw attention to the
mark when there is but one, and, if there are several corrections in
one line, it prevents them being confused.”
One line drawn underneath indicates Italics.
Two lines — small capitals, written sm. caps.
Three lines — large capitals, written 1. caps.
To change italics into ordinary type, draw one line underneath,
or a row of dots, and put Rom. in the margin. The suppression
or addition of a paragraph causes expense, not for the mere printing,
but on account of the re-setting of the text.
Slanting lines on the left side of a printed page apply, in order
of sequence to the left side of a column, thus :
a / o/ sepe/rate kingdu/m, dating from the first word ;
marginal corrections inserted on the right side of a printed page
are also placed on the left side of the slanting stroke, and date
from the centre of the column in order of sequence — thus :
Sepe/rate kingdu/m. a/ o/
The diagram shown is an extract from Baedeker’s ‘ Belgium and
Holland. ’
The corrected passage will read as follows : —
At the upper enl of the Petit Sablon, a small
square surrounded by a handsome railing, rises
the Monument of Counts Egmont and Hoorn
(PI. 39) by Fraikin, which formeily stood in
front of the Maison du Roi (p. 104). The lower part
is a fountain, above which rises a square
pedestal in the later Gothic style. It contains a
choice picture-gallery.
Behind this is the palace, once the resid-.n e
of Count Egmont, which was damaged by fire.
A few houses above the palace, is the prison ; a
monastery formerly occupied this site.
The Index.
At one time it fell to my lotto construct an index of an elaborate
nature which with infinite toil was made correct. I told Daniel
Hanbury of my trouble and he said : ‘ ‘ Come and see my index,
now in progress, of the ‘ Pharmacographia.’” Since then I have
prepared many indexes and have always followed his plan.
Take and label twenty-six jars or tins according to the letters of
the alphabet, and in a narrow-paged ruled book, carefully write
the desired index words, sheet by sheet as the book is passing
through the press.
At your convenience cut these off in slips and let them drop
into their labelled receptacles ; the final set may be taken from the
last proof-sheet; till then it is advisable to work only from corrected
revise or an error may creep in.
Now place the contents of letter A upon a smooth polished table
and arrange them there. When done, fold them up in long rolls
of paper a little wider than the slips, Aa being in the last, top
fold, Ab next, and so on in like order. The whole letter need not
be finally arranged at once, but divided into say, a dozen sections — -
for instance, Aa to Ac inclusive, and these tied up and put by for
a more leisure hour, so as not to interfere with other engagements.
The first letter of the alphabet befng complete, fix the slips upon
the pasted pages of a second ruled book ; do not paste the slips.
No subsequent correction is required — the copy is in perfect
condition and ready for the printer’s hahds. Proceeding in this
way it matters not whether 1000 or 10,000 entries are concerned ;
it becomes simply an affair of more or less time, not of additional
ill-directed labour. S appears to be the longest and most difficult
letter to arrange.
The Old Pharmaceutical Journal.
The original series of the Pharmaceutical Journal was printed
at Beaufort Buildings in the Strand. It was then a monthly
publication and the editor was not distracted by producing it once
a week. The leading articles were almost invariably written by
Jacob Bell, who was energetically assisted by Dr. Redwood, then
in the zenith of his powers and a tower of strength. John
Barnard lent invaluable and painstaking assistance in the general
compilation ; Daniel Hanbury was its most learned contributor,
Apbil 24, 1897.]
PHARMACEUTICAL JOURNAL.
353
and I had my share. The Journal was “ made up ” at the editor’s
private house in Langham Place, just opposite the church, the
event being solemnised by high tea, at which visitors, notably
Edwin Landseer, Dallas of the Times and others were often
present. They retired as soon as the five mentioned began their
work, each writer being personally responsible for the press
corrections of his own articles.
The Printing Office was under the proprietorship of Charles
Whiting, one of the handsomest men in London, who before he
took to printing was considered an expert in the choice of drugs.
The office, which passed first into the hands of Rimmel, the
perfumer, and which now forms part of the Savoy Hotel, was not
invaded by any modern fittings. Huge mahogany desks and high
stools constituted the sole furniture, save only an enormous stove,
the odour of which pervaded this department. An elderly person
called Birtles — “a character in his way,” was head clerk and general
factotum. I found him one morning in despair for he had received
a manuscript with Chinese lettering and was in doubt which side
up to print. I suggested, “ Better toss : heads one way and tails
the other.” “No,” he -replied, “the writer I know, is rather
particular.”
I had myself a bad turn with these same hieroglyphics when
called upon to reprint ‘ Chinese Materia Medica.’ Many of the
blocks were temporarily lost and had to be recut — neither the
engravers nor I were on speaking terms with Celestial literature.
From the office a creaking staircase, constructed on the model of
a corkscrew, led to the machine room on the top floor ; it overlooked
the Thames and a wide expanse of sludge forming a long coal-
wharf, since converted into the gardens of the Embankment. One
corner of the room was partitioned off for editorial purposes and
provided with a high stool with four precarious legs requiring
management on the sitter’s part.
There the contributors to the Journal made their own press
corrections.
At first the aspect of the place was most confusing, but the eye
soon began to be accustomed to the strange scene and the ear to
the peculiar cranking noise of the machines in motion. It was-
entirely hand-printing, steam had not then been introduced into
the establishment. Printing-works differ much in the nature and
number of mechanical appliances, but about the same impression
is produced upon a stranger’s mind : there at various desks the
compositors are setting up the type, a complete assortment of
which is called a fount. The different letters are arranged in an
upper case, holding capitals and less used sorts ; while a lower case
holds the smaller letters — neither placed alphabetically, but those
most used being nearest the hand of the compositor.
The proportion is curious — Chambers says that the letter “e”
requires 12,000 types ; “a,” 8500; “ i,” “ n,” “o,” “s,” require
8,000 each ; and “z,” 200.
My experience is that “ c ” and “ s ” are the chief insertions in a
science index.
The type-letters are placed one by one with wonderful dex¬
terity in the setting-stick, a metal instrument regulated to any
width of line.
All skilled manual labour excites the admiration of the looker-on,
and this is notably the case in the composing room. When the
stick is full, the type is put into a galley, a brass tray with wooden
sides, about eighteen or twenty inches long.
This contains, when filled, about a page of matter in one long
column, and is then wedged tight.
From this, transferred to the printing press, a proof is taken,
read and corrected, and in that state the author gets his “ clean
proof.” “Display” means skilful arrangement of the lines or
spacing ; the made-up pages are locked in iron frames called
chases, from the French, chasse ; sets of them are called formes, so
spelt, and the whole assortment is a pie. The final correction is
entrusted to the “ reader.” •
Those pale faced boys who wait about, are familiarly known as
printers’ devils ; they fetch and carry and chase each other up and
down the stairs ; they used to gladden an author’s heart when he
heard their welcome knock ; we are more prosaic now and receive
copy through the post.
The reader at the office is usually the head printer who ‘ ‘ corrects
for literals ” ; there is also the professional reader who undertakes
press correction and may have an office of his own. Great
publishing firms are indebted to another class of “ reader” who is
an accomplished scholar and on whom depends the acceptance or
rejection of a work.
I thank you for having listened to all this. Every description of
literary work is the better for the pains bestowed upon its
composition even though it be purely technical, and depend
chiefly on its matter, not its style.
An indolent habit may cause genius itself to become latent, as gold
is hidden in the earth and unproductive till dug out with labour
by the hand of man.
LEGAL HINTS FOR PHARMACISTS.
( Continued from page 268).
Medicine Stamp Acts.
The statutes relating to the preparation and sale of medicines
or specifics recommended for the cure or alleviation of human ail¬
ments are both numerous and complex. They extend from 25
Geo. Ill, c. 79, which first gave legal recognition to the “secret
preparation” industry, to 38 Viet., c. 23, which, by reducing the
licence duty to five shillings, encouraged the multiplication of
makers and vendors, and paved the way for the subsequent enor¬
mous development of the public taste for nostrums. Perhaps no
series of statutes is so misunderstood as the Medicine Stamp
Acts. They are rarely even referred to correctly, and a stamped
medicine is nine times out of ten popularly, and more often than
not officially, described and known as a “ patent” medicine. That
there is no statutory or legal authority for the practice has been
pretty conclusively shown by the judgments in Pharmaceutical
Society v. Piper and Pharmaceutical Society v. Fox, which defined
the meaning of the words “patent medicines ” in Section 16 of the
Pharmacy Act, 1868, to be, to put it succinctly, medi¬
cines prepared under the authority of a patent in force.
Why the term ‘ ‘ patent ” should have been bestowed upon
stamped nostrums now seems incomprehensible ; for the
compulsory affixing of an ad valorem stamp to a preparation
cannot reasonably lead any maker or vendor to suppose that he
thereby acquires the privileges accorded by the Patents Acts. Nor
can it be claimed that the stamp duty only applies to medicinal
preparations for which Letters Patent have been granted. As a
matter of fact, patenting is only one of the causes which bring
medicines under liability to duty. The indiscriminate use of
“ patent ” and “ proprietary ” as synonymous terms is doubtless a
survival of what was, at the time of the first Stamp Act in 1783,
the fittest description of the medicines chargeable. That Act in
effect, though not in intention, taxed little else but medicines sold
by virtue of Letters Patent, and it might with good reason have
been styled a Patent Medicine Act. It remained in operation,
however, for two years only, and gave place to the Act 25 Geo. III. ,
c. 79, which greatly enlarged the incidence of the duty and
removed all ground for using the word “patent” as a generic
term to describe stamped medicines. There can be little
doubt, however, that the confusion of terms has operated
largely in favour of the nostrum proprietor, and in the present
day a large portion of the public regards the Government stamp
as implying some sort of guarantee of the purity or efficacy of the
preparation it envelopes, notwithstanding the official disclaimer on
the stamp itself.
In dealing with the medicine stamp and licence duties one finds
considerable difficulty in the way of systematising the mass of
details connected with the subject. Partaking of the nature of
grammatical rules, the hardest portion of which are the exceptions,
the Medicine Stamp Acts present many problems in their exemp¬
tions and qualified exemptions which might afford reasonable
scope for the acumen of the proverbial Philadelphia lawyer. We
propose as the most comprehensive method of placing the subject
before our readers to first define the stamp duty, then to deal with
the licence imposed upon those who make or sell medicines
charged with duty, and finally to discuss statutory liability, the
practice of the Revenue Department, and the various exemptions
at present recognised.
Stamp Duty. — No better description of the duty can be given
than that expressed in the Schedule to 44 Geo. III. , c. 98.
“For and upon every Packet, Box, Bottle, Pot, Phial, or other Inclosure con
taining any Drugs, Herbs, Pills, Waters, Essences, Tinctures, Powders, or other
Preparation or Composition whatsoever used or applied or to be used or applied
externally or internally as Medicines or Medicaments for the Prevention, Cure,
or Relief of any Disorder or Complaint incident to or in any wise . affecting the
Human Body, which shall be uttered or vended in Great Britain where such
Packet, Box, Bottle, Pot, Phial, or other Inclosure with its Contents shall not
exceed the Price or Value of One Shilling . - . £0 0 1£
$. cl. 8, d .
Shall exceed 1 0 and not exceed 2 6 . 0 0 3
„ 2 6 „ 4 0 . - . 0 0 6
354
PHARMACEUTICAL journal.
[April 24, 1897
s. d. s. d. £, s. d.
Shall exceed 4 0 and not exceed 10 0 . «... 0 1 0
„ 10 0 „ 20 0 . . 0 2 0
„ 20 0 „ SO 0 0 3 0
„ 30 0 „ 50 0 0 10 0
„ 50 0 . 1 0 0
Any person selling without a stamp any article contemplated
by the foregoing is liable to a fine of £10, and it will be no
defence for him to urge that he is a licensed vendor. Ordinary
adhesive stamps must not be used, the proper stamps being
obtainable at Somerset House. The stamp must be so affixed to
the inclosure containing the medicine chargeable with duty, that
the contents cannot be reached without tearing the official label
and rendering it incapable of further use.
The ideaof the Inland Revenuegranting a discount for cash may be
startling, but it is nevertheless true that persons purchasing at one
time £30 worth and upwards of medicine stamps may claim a
discount of 1 per cent. Spoiled unused stamps may be exchanged
for new ones under certain conditions and subject to formalities
necessary to safeguard the Revenue from fraud. Those desirous
of effecting such an exchange must apply to Somerset House, and
should state in the application full particulars of their claim. The
exchange is always effected in kind for the Commissioners are not
empowered to make any payment in respect of defaced or spoiled
stamps returned to them.
Licence Duty. — Every person in Great Britain who is the pro¬
prietor, maker, or compounder of any drug, preparation, or com¬
position used or to be applied in any way for the prevention
or relief of any disorder or complaint incident or in anywise
affecting the human body, must take out an excise licence. The
same compulsion attaches to every person vending or exposing, or
even keeping for sale any of the articles above described. The
licence costs 5s., and expires on September 1 of each year. It is
dated the day it is issued, but a whole year’s duty is always
charged, though the period covered may, in the case of a person
commencing business, be for a term less than a year. The
licence is transferable to a successor in business, and the licencee
is not, as in the case of methylated spirits or stills, subject to have
his premises entered and surveyed . A person vending or exposing for
sale in several shops must possess a licence in respect of each shop.
A licence is not now issued in respect of vehicles from which
medicines are sold. The penalty for selling without a licence is
£20.
Liability. — “What constitutes liability?” is a question often
asked, and is not very easy of response. It might indeed seem
rather less arduous to effect a negative definition by specifying
what does not constitute liability, for the statutory definition is
capable of very wide application. It is only fair to the
authorities, however, to say that far from pushing the interpreta¬
tion of the law to its extreme limits they rarely employ to the
full the powers they possess. The statutory definition of the
grounds for liability may be summarised under four heads : —
(a) Secrecy or specialty in preparation.
(b) Proprietary right.
(c) Patent right.
(d) Recommendation.
(a) Secrecy or Specialty. — A medicine for which there is
advanced a claim to any secret or special art in the preparation
is chargeable with duty, and the vendor of such an article must
take out the Excise licence. It is quite immaterial whether there
be or not any foundation for the claim, nor does it follow that such
claim must be specifically advanced in words to make it valid
under this heading. It is rarely the case now that the ‘ ‘ occult
secret ” is more than implied, but implication is quite sufficient.
Take a supposititious case. “The Bloomsbury Cough Linctus ”
would be liable inasmuch as the words would be open to the con¬
struction that the preparation was compounded after a special
recipe. The same interpretation may be given when
such words as “ beware of imitations,” “ see that the
signature X is on the box,” and so forth, are employed, for
such directions would be meaningless separated from the conception
of special art or care in making ; in fact, the object of the words
appearing is to convey to the public that the medicine is a specialty
possessing superior merit to similar preparations made after the
ordinary formula, and liability therefore ensues. The schedule to
the Act 52, Geo. III., c. 150, gives many examples of medicinal
substances which are chargeable under this heading. As typical
cases may be cited “American alterative pills,” “Andalusian
water,” “Arabian balsam,” “Balm of Mecca,” “Dutch drops,”
“Gardener’s ointment,” “ Orme’s medicine,” etc., etc., all of
which imply secrecy either as to the ingredients or to the mode
of compounding, or to both. Geographical names are thus potent
factors in bringing the medicines they refer to within the scope
of the duty. Fancy titles are open to the same objection though
from a somewhat different cause. The title may or may not be
registered as a trade mark. If it is, it will have no reference to
the character or quality of the medicine and will not be a
geographical name, otherwise it would not, under Section 64 of the
Patents, Designs, and Trade Marks Act, 1883, be registerable at all.
What would be the use of such a mark to a “ patent” medicine
vendor without the addition of either specific words to attract
attention to the special value of what he has to sell, or of some
distinctive design or device otherwise explaining its virtues ? It
is precisely such additions which bring liability to duty. On
the other hand, if the fancy word is not registered it most
probably bears words self-explanatory of the curative power
of the medicine, or it carries the implication of special- art
in the making, otherwise its suitability from a commercial point of
view would be open to doubt. Registration of a trade mark for a
medicine is very apt indeed to make the medicine liable under
one or other of the heads of chargeability, for registration involves
a public advertisement of the mark, and considerable ingenuity
would have to be exercised to steer clear of the “ recommendation ”
rock of liability. Moreover, consider the effect of registration. It
confers an exclusive right of user in respect of the mark registered
— a protected proprietorship, assignable and transmissible like any
other commercial asset. Now the idea of exclusive right in a mark
is very little removed from the assumption of proprietary right in
the article sold under it, and in actual practice it is found that very
little enterprise on the part of the vendor is necessary to render the
two things identical. Broadly speaking, then, geographical and
fancy names should be eschewed. Another phase of the claim to'the
occult is the use of celebrated names in the possessive case. The
following label would be liable under two heads
Dr. Hunter’s Liver Mixture.
Wm. Jones, Chemist,
London.
Firstly it implies that the remedy is compounded after a special
recipe, and secondly it might be taken to convey that Jones had
some proprietory right in Hunter’s formula. Jones would,
however, escape liability if he stated on the label the ingredients
of the preparation, for by so doing he would no longer be open to
the charge of claiming any occult secret or art in the making
thereof.
THE LIMITATIONS OF STANDARDISATION.
Wherever medicinal action obtains with a vegetable drug the
soluble principles of the latter are the therapeutically active ones,
and while all the soluble principles are not necessarily of thera¬
peutic worth, it is impossible, in the immature condition of
rational therapeutics as to the relative values of different drug
extractives, to say that any given extractive is inert or without
medicinal activity. Clinical evidence, and not chemical, determines
the actual therapeutic worth of a drug and its preparations. The
action of a drug, in modifying the contents of a diseased tissue,
modifies one or all three cellular activities, nutritive, functional
and reproductive. The functional activities, being the most
obvious, have been the most studied by therapeutists. Indeed
the modern description of drug action is almost wholly limited to
a description of the functional disturbances caused by its use.
And yet, what is as important, the modifying influence of drugs
upon the nutritive and reproductive activities of cells in disease,
has received relatively little attention. Until this be done, no
complete knowledge can be had of drug action in human tissues.
Many of the larger manufacturers lay great stress upon the
fact that the more poisonous fluid extracts made by them have
been standardised to contain a given amount of so-called active
principle, and one might infer from the claims made for such fluid
extracts that these principles represented the entire therapeutic
activities of drugs. No claim could be further from the truth.
The so-called active principles of a drug represent their individual
therapeutical actions only, and nothing more. The entire thera¬
peutic effect of a drug can only be had from the drug itself, or a
preparation containing all the therapeutically active principles of
the drug. Hence, from a therapeutical point of view, for example,
aconitine, digitalin, strychnine, brucine and quinine, represent
their individual actions only, and not the therapeutic actions of all
April 24, 1897]
PHARMACEUTICAL JOURNAL.
355
the constituents found with them. The proportion of the so-called
active principle is no index of the proportion of the other
proximate constituents of the drug. As a rule, the content of
alkaloid is simply an indication of the amount of that proximate
principle of the drug which produces the greatest functional
disturbance in cellular tissues.
The value of standardised fluid extracts over those not standard¬
ised, in actual medical practice, has been much exaggerated. The
fluid extracts that are usually standardised by the manufacturers
and not by the Pharmacopoeia, are those of aconite root, belladonna
leaves, coca, colchicum root, colchicum seed, conium fruit, digitalis
leaves, gelsemium, hyoscyamus and the like. .When the physician
exhibits these fluid extracts clinically, what does he do ? He gives
the preparation in small and gradually increasing doses, until he
gets full physiological effects, and then he stops the drug. Now,
wlSit practical difference to the physician does a slight variation in
the proportion of the so-called active principle make ? — especially
in view of the fact that, with the possible exception of preparations
of cinchona, nux vomica, opium and one or two others, every
manufacturer is a law unto himself regarding the strength of
standard adopted, and the manner of following that standard,
which is fully as important as the matter. True, many manu¬
facturers apparently adopt the same standard, but they reserve for
themselves the right of using what working details of assay they
wish- In the immature condition of drug assay, it is well known
that variable results are obtainable with many drugs with the
same processes as worked by different persons, due probably, in
some cases, to the difficulty of getting the final products pure.
Scores of modifications in the working details of processes of
drug assay have been recommended in the last few years in the
pharmaceutical prints, many of them from the laboratories of
manufacturers. It is obvious that, in the opinion of their authors,
these changes must have been improvements, or they would not
have been recommended, and they have probably been adopted by
some firms. But, in the absence of any general agreement, it is
hardly reasonable to believe that all recommendations for changes
in processes of assay have been adopted by manufacturers, and
thus we may have the same processes in use by different manu¬
facturers with varying modifications in working details, and of
course yielding variable results. Until manufacturers of fluid
extracts not standardised by the Pharmacopoeia, but standardised
by themselves, get together and agree upon the working details
of their processes of assay, the commercial standardised fluid
extracts will not be uniform in content of active principles.
As it is not pracoicable for the average physician to specify, in
his prescriptions, the make of one particular manufacturer, nor
practicable for the retail pharmacist to keep all makes of stan¬
dardised fluid extracts, it is idle to over-estimate their importance.
Perhaps the strongest example of standardisation run mad is to
be found in the commercial attempts made to standardise fluid
extract of digitalis. Here is a drug for which no practicable
method of assay has yet been found, even with years of chemical
research. This does not deter manufacturers. They simply assume
certain standards of extractive, and claim that the drug is stan¬
dardised, despite the fact that the percentage of extractive varies
with the alcoholic strength of menstruum used to exhaust the
drug, and the extractive may contain some or but little of the
active principles, or it may contain none. One manufacturer mar¬
kets his fluid extract of digitalis, and says that his standard is 20
per cent, extractive (strength of menstruum not given) ; another
has as his standard fully 25 per cent. , with a 75 per cent, alcoholic
menstruum ; another has as his standard 30 per cent, (strength of
menstruum not given). Here is a difference in extreme limits of
50 per cent, between the strongest and the weakest extractives,
and the difference is more than this if the first-named and the last-
named fluid extract have had used for their making weakly alco¬
holic menstrua.
Now, what happens? The retail druggist may have prescrip¬
tions calling for all these makes of this fluid extract. Suppose that
he makes his tincture extemporaneously from the fluid extract.
One day a prescription for the tincture may be made from the
20 per cent, product, the next day from the 30 per cent, product,
and the next day from the 25 per cent, product. Is there unifor¬
mity in this ? And would a tincture made from good selected
digitalis leaf, by the retail pharmacist himself, vary as greatly as
these commercial fluid extracts, diluted with alcohol and water ?
While an exaggeration of the value of drug assay is to be depre¬
cated, it is equally unjust to ignore its growing importance. A
great amount of valuable work has been done in recent years, but
far more remains to be done, especially with regard to the clinical
value of different proximate principles of plants in disease treat¬
ment. — Alumni Report.
PHARMACEUTICAL SOCIETY.
EXAMINATIONS IN EDINBURGH.
April, 1897.
■v _
MAJOR EXAMINATION.
Candidates examined . 5
,, failed . 4
„ passed . 1
Rattray, David Smith.
MINOR EXAMINATION.
Candidates examined . 180
,, failed . .. . 129
,, passed . 51
Ashdown, William Percy Charles.
Bain, James.
Bell, Henry Robert Kerr.
Bowell, Horace James Whitney.
Bowman, Alexander Nasmyth.
Cheyne, William Alexander.
Chrystall, Robert.
Cockshott, Frederick.
Dannatt, Philip.
Davies, David Arthur.
Douglas, J ames Forrest Reid.
Duncan, Hubert.
Duncan, John.
Emsley, Robert Bums.
England, Herbert.
Fairbairn, James Hume.
Forster, William.
Gee, James Edwin.
Gilchrist, Adam.
Gordon, David.
Graham, Margaret Thompson.
Grayson, Joseph.
Griffiths, Arthur Valentine.
Guthrie, James Strachan.
Heraughty, Thomas.
Wade,
Hirst, Frederick Beaumont.
Hodgson, Baron Cuthhert.
Hodgson, John Birtwell.
Holland, George Arthur.
Innes, William Rome.
Jack, William.
McBride, Alexander.
McLaren, Arthur.
Marshall, Richard Harrison.
Maxwell, John.
Milne, Hamilton.
Moss, George Henry.
Officer, Cohn.
Patterson, John.
Piggin, Leonard William.
Pilgrim, Walter Ernest.
Pilkington, John, jun.
Reid, Alexander.
Robertson, David Smart.
Robinson, Charles.
Rollin, Arthur Stanley.
Sharpies, Robert.
Speedy, William.
Spence, Thomas.
Thomson, Charles.
Margaret Callander.
NOTES AND FORMULA.
Lanolin Cold Cream.
Lanolin, ^iv. ; vaselin alb., ,fij. ; lanolin soap, ^iv. ; aquas rosaa,
^iv. Dissolve soap in rose water, melt the two other ingredients,
stir in the solution, and continue stirring until cold. — Brit. Joum.
Derm., ix., 69.
Permanent Camphor Powder.
Schmidt proposes dissolving the camphor in benzin with a boil¬
ing point below 80° C. , putting it in a distilling apparatus and
heating until the liquid passes over. On cooling, the camphor pre¬
cipitates in the form of a fine white powder, which separates by
filtration. This powder will not pack or run together at ordinary
temperatures. — Pharm. Era, xviii., 140.
Tubercule Bacilli in Butter.
Tubercule bacilli may be separated from butter by melting 5 g.
of butter, at 50° in a test tube, shaking through with warm water,
closing the tube with an india-rubber cork, allowing it to stand
upside down. After cooling the bacilli will be found in the water.
— Pharm. Centralh., xxxviii., 45.
New Mown Hay.
01. bergam. , l-8 ; otto, 0-15 ; ol. neroli, 0'1 ; ol. lavandulse, 0’1 ;
ol. caryoph., 0'05 ; rhiz iridis flor., 10'0; fab. tonca cons., 5'0 ; fol.
patchouli, 0'2 ; fol. urticas, 2 0 ; acid benzoic, 0 '5 ; vanillin, 0 '5 ;
spir. vini, 200. — Zeit, d. allcj. rest. Apoth. Verein, 31.
356
PHARMACEUTICAL JOURNAL.
[Apeil 24, 1897.
THE STUDENTS’ PAGE.
SOME NOTES ON CRYPTOGAMS.
HEPATICiE.
The male organs or antheridia, as a rule, are produced separately
from the female or archegonia, in some instances on the same
plants, in others not. In certain species, however, the antheridia
and archegonia may be found intermingled in the same perianth.
In the foliose Hepatic* the female reproductive organs generally
occupy the end of the primary axis or special lateral branches
(Fig. 1), whilst the male ones, as a rule, are found in the axils of
Fig. 1. — Radula complanata. — A, fruit ; B, fruit after dehiscence, showing the
four valves (magnified) ; C, colesule or perianth, within which may he seen the
calyptra (D) ; E, stem and leaves magnified, showing the adpressed inferior lobe.
leaves, either singly or in groups. Each antheridium consists of
a globose or oval body surmounting a short pedicel. The body of
Fig. 2.— Radula complanata.— F and G, spores and bispiral elaters of same
(magnified).
the antheridium encloses within it the mother cells of the anthero-
zoids. When mature these escape on access of water and separate,
when the antherozoids soon become free.
The female organs or archegonia are enclosed surrounded by a
few modified leaves or bracts, forming the perichaAium. The
archegonia vary in number from three to ten, of which only one
D
Fig. 3.— Marchantia polymorpha. — A, male frond ; B, female frond, showing the
reproductive organs on stalked receptacles, and gemmae in circular raised cups ;
D, magnified gemma of same.
or two become fertilised and develop into fruit. After the
appearance of the archegonia a cellular ring is formed around them
and grows into a perianth or colesule, which, when fully developed,
encloses them, ultimately appearing above the perichsetial leaves.
The perianth differs considerably in different species, as will be
seen from the examples figured.
The archegonium becomes developed into a sporogonium,
with a rudimentary pedicel enclosed in a membrane attached
at the base, and called the calyptra. When ruptured by the
upward growth of the sporogonium it remains in the perianth
surrounding the base of the fruit-stalk (Fig. 4). The sporogonium
Fig. 4. — Pellia epiphylla, showing fruit produced in the upper surface of the
frond ; A, globose capsule ; B, same after dehiscence ; C, perianth ; D, exserted
calyptra.
or capsule now soon appears above the edge of the perianth in the
form of a globose or ellipsoid head, which soon splits into valves,
setting free the contained spores and some of the elaters (spiral
threads) (Fig. 2).
In the frondose Hepatic* or Liverworts the antheridia are
imbedded in the fronds, or in specially-stalked receptacles, whilst
the female receptacle is usually stalked, and the expanded apex is
lobed in various ways, or the archegonia are produced on the lower
surface of the receptacle, or in the upper surface of the frond as
the case may be (Figs. 3 and 4).
NOTES ON THE B.P.
Cupri Sulphas. — When copper is heated with strong sulphuric
acid (it has no action on dilute sulphuric acid), copper sulphate is
formed, but the hydrogen displaced is not evolved (as it is when
zinc acts upon dilute sulphuric acid), since the hot strong acid is
reduced by nascent hydrogen with formation of water and
sulphurous acid. The latter at the temperature employed is
decomposed into sulphurous anhydride (sulphur dioxide), S02, and
water.
(i.) Cu + H„S04 = CuS04 + H,.
(ii.) H2S04 + H2 = H90 + HoSO,.
(iii. ) H2S03 = HaO + S02.
The reduction of the sulphuric acid may even result in the pro¬
duction of sulphuretted hydrogen —
H2S04 + 8H = H2S + 4H20,
and the sulphuretted hydrogen precipitates black copper sulphide
from some of the previously-formed sulphate—
CuS04 + H2S = CuS + H2S04.
The presence of small quantities of iron as impurity cannot be
detected by the usual test for iron — ferrocyanide of potassium,
since the blue would be masked by the red copper ferrocyanide.
Chlorine is added to convert ferrous into ferric salt, and on the
addition of ammonia ferric hydrate will be precipitated, the cupric
hydrate re-dissolving in excess of ammonia.
Decoctum Aloes Compositum. — The carbonate of potassium
aids the solution of the extract of aloes and myrrh. This decoc¬
tion requires carefully watching as it froths a good deal and
readily boils over. The tincture of cardamoms serves the double
purpose of carminative and preservative, and is added to the
cooled decoction to avoid loss of aroma and alcohol. Alkaline
solutions of aloes are said to lose their activity by exposure to air,
hence the precaution enjoined in the last paragraph of the official
directions.
Decoctum Cinchona. — Water only partially exhausts cinchona,
a considerable quantity of alkaloid being left in the marc. The
decoction is, however, largely used when a mild tonic preparation
of cinchona is desired, particularly in irritable or weak conditions
of the stomach, when acid preparations like the infusion or the
nauseous fluid extract would not be tolerated. During cooling the
decoction deposits a quantity of amorphous, chiefly colouring,
matter, having no medicinal or alkaloidal value ; hence the direc¬
tions to strain when cold so as to remove this inert deposit, which
would render the decoction unsightly.
April 24, 1897]
PHARMACEUTICAL JOURNAL.
Pharmaceutical Journal.
ESTABLISHED 1841.
Editorial Office: 17, BLOOMSBURY SQUARE, W.C.
Publishing and Advertising Office : 5, SERLE STREET, W.C.
LONDON : SATURDAY, APRIL 24, 1897.
AN ANTICIPATION OF DARWIN AND WEISMANN.
Great ideas and novel theories frequently suggest them¬
selves to many minds before they assume definite shape and
are published to the world, hut probably no more striking
instance of this has occurred than that which serves
Professor E. B. Poulton as a text, in the current issue of
Science Progress. James Cowles Prichard, a Bristol
physician, who was horn in 1786, appears, according to the
account now published, to have anticipated modern views on
evolution to a remarkable extent. He was a member of the
Society of Eriends, and his contributions to science were of
such value that he is regarded as the great pioneer of modern
anthropological and ethnological research. Amongst other
achievements, he was able to prove “ that the Celtic nations
are allied by language with the Slavonian, German, and Pelas-
gian (Greek and Latin), thus forming a fourth European branch
of the Asiatic stock (which would now be called Indo-
European or Aryan).” But observes Professor Poulton,
although Prichard’s memory is much honoured, it appears
that in one important respect he has not hitherto received
his due, as in the second edition of his ‘ Researches into the
Physical History of Mankind/ he seems to have anticipated
in the dearest manner the arguments which have recently
been advanced by Weismann in favour of the non- trans¬
mission of acquired characters. More than this, he
apprehended with perfect clearness the fact that domesticated
races of animals and plants have been produced by the
selection of man, and not by favourable surroundings,
careful training, or cultivation. He believed in the possibility
of organic evolution, and supported it by excellent arguments
which still have the strongest weight. “ He even recognised
the operation of natural selection, although he assigned to it
a subordinate role” But what is described as being his
most important anticipation is a masterly discussion on the
transmission of acquired characters, “ a discussion in which
the distinction between acquired and inherent or congenital
characters is clearly drawn, and many of the most difficult
cases are fully argued out, the conclusions reached being
those independently arrived at by Professor Weismann over
half a century later.”
In discussing the causes which have given rise to varieties
in the human species, Prichard says it appears to be a general
fact that “ all connate varieties of structure, or peculiarities
which are congenital, or which form a part of the natural con¬
stitution impressed on an individual from his birth, or rather
fiom the commencement of his organisation, whether they
happen to descend to him from a long inheritance, or to
spring up for the first time in his own person — for this is
perhaps altogether indifferent — are apt to re-appear in his
357
offspring.” To express the matter in other words, the organisa¬
tion of the offspring is always modelled according to the
type of the original structure of the parent.” Prichard
further states that, ‘ 1 On the other hand, changes
produced by external causes in the appearance or consti¬
tution of the individual are temporary, and, in general,
acquired characters are transient ; they terminate with
the individual, and have no influence on the progeny.”
It is noted that the second conclusion is more difficult to
establish than the first, since the proofs must needs be of a
negative kind. At the same time, it is continued, there is
no want of evidence of this description, and emphasis is laid
upon what “ seems to be the law of the animal economy,”
that the organisation of the offspring, which follows the type
given by the natural and original structure of the parent, is
unaffected by any change the latter may have undergone,
and uninfluenced by any new state it may have acquired.
In considering the effects of disease, Prichard points out
that we cannot discern any essential circumstance in which
changes produced by art or by casual injury differ from
those which are effected by other external causes. “We
should therefore suppose from analogy that the latter are
not more communicable to posterity than the former, and
this presumption is confirmed when we inquire into facts.”
It is shown that the constitutional effects of small-pox,
measles, scarlatina, whooping-cough, etc., which render
persons who have suffered from those diseases more or less
immune are never hereditary, and the change effected is
regarded as being a permanent state of the constitution,
which lasts as long as the individual. “ Those imperceptible
modifications in the bodily structure which render the con¬
stitution incapable of being acted upon by certain morbid
poisons are governed by the same law, as far as regards
hereditary descent, as the observable changes of form which
are induced by art or accident.”
The essential distinction between inherent hereditary and
acquired non-hereditary characters is clearly recognised by
Prichard, in the general statement that each individual being
has certain laws of organisation impressed upon its original
germ, according to which the future development of its struc¬
ture is destined to take place. “ These inbred or spontaneous
tendencies, governing the future evolution of the bodily
fabric, cause it to assume certain qualities of form
and texture at different periods of growth. Erom these
predispositions are derived the characteristic differences
and the pecularities of individual beings. Now it appears
that such spontaneous tendencies are alone hereditary, and
that whatever changes of organisation are superinduced by
external circumstances, and are foreign to the character of
structure impressed upon the original stamina, cease with the
individual and have no influence on the race. ” Yet, it is observed,
this law of hereditary conformation exists with a certain latitude
or sphere of variety, but whatever varieties are produced in the
race, have their beginning in the original structure of some
particular ovum or germ, and not in any qualities superinduced
by external causes in the progress of its development.
As Professor Poulton pertinently remarks, these sentences
might well have been written to-day, to sum up the results
of all our observations on such subjects, for though the
results described have been summed up at greater length
and in more technical language, “ Dr. Prichard’s statement
contains everything that is valuable and essential in every
later attempt.”
358
PHARMACEUTICAL JOURNAL.
[April 24, 1897.
ANNOTATIONS.
The Proposed New Bye-Laws received further approval at
meetings of the Aberdeen and Plymouth local associations last
Wednesday, when resolutions were passed to that effect, as
reported at page 362. At Aberdeen a motion expressing disap¬
proval was brought forward and supported by its mover on the
assumption that the Pharmaceutical Journal swallowed up the
funds derived from the examinations, but the fallacy of that
assumption was very clearly pointed out, and the voting
showed that the unfounded nature of the statements which
have been put forward on this subject is being properly appre¬
ciated. At Plymouth Mr. Park showed that there is no truth in
those statements, and for that purpose he availed himself of the
facts stated in this J ournal, at page 255 of the number for March 20.
Anyone desiring to be correctly informed on this subject will
there find all that is requisite for demonstrating the value of
the Society’s Journal to its members, associates, and students, as
well as its utility as a medium of communication for all directly or
indirectly connected with the business of chemists and druggists.
The Comptroller-General op Patents states that the number
of applications for patents, which in 1895 showed a decrease of
324 upon that of the previous year, increased in 1896 by 5132, an
increment four times as large as the average yearly increment.
The total for the year was 30,194, and applications came in during
the last two months of the year at the unprecedented rate of 700
per week. The increase was mainly in provisional specifications,
and the principal cause of it appears to be the development of the
cycle industry. Applications for the registration of trade marks
numbered 9466, as against 8272 in 1895. During the same period
3243 trade marks were advertised, and 2917 were registered.
Fruit Preservation has engaged the attention of the Kent
County Council, and particulars are published of an interesting
experiment in which cold storage was resorted to. The stores were
kept at steady temperatures of 30° to 40° last season until near the
end of the year, and the results recorded are fairly satisfactory.
The fruit lost weight somewhat during the refrigerating process,
moisture being absorbed from it by the air and deposited on the
colder surfaces of the brine walls, from which it was drained away.
The loss per week amounted to 1 -5 per cent, of the weight of the
fruit. Summer apples remained sound, but were somewhat soft
and not so good in flavour. On the other hand, winter apples were
of as good flavour as when put in, and were fully as hard and sound.
Gresham Lectures will be delivered on Tuesday next, April 27,
and three following days, in commemoration of the tercentenary
of Gresham College, by Dr. Symes Thompson, who has just
returned from a tour in the East, where he has visited the sites of
the ancient universities of Athens, Constantinople, Ephesus,
Damascus, and Alexandria, and Heliopolis. The subject of the
lectures will be the medical history of Gresham College during
three centuries. The first will be devoted to an account of the
foundation and progress of the College, the second to ancient and
modern universities, and the others to the Gresham professors of
physic. It is noteworthy that the six faculties ordered at the
Gresham Foundation — law, physic, divinity, astronomy, geometry,
and poetry — are the same as were taught at On (Heliopolis).
The University Extension Summer Meeting will be held in
Oxford between July 31 and August 25, and for the convenience of
students who cannot remain for the whole time the meeting will
be divided into two parts. There will be daily classes in botany,
chemistry, and physics, adapted to the requirements of County
Council and other teachers, special reference being made to the
fitting up of home-made apparatus. A special feature of the meet¬
ing will be a class in the English language, conducted by Dr.
Henry Sweet, and intended for the foreign students who attend
the summer meetings in increasing numbers. Their presence tends
to make the meetings valuable for the interchange of ideas between
English and foreign teachers and others interested in educational
problems. Official programmes of the meeting may be obtained
from the Secretary, University Extension Delegacy, Oxford.
A National Photographic Record is proposed, and the British
Museum authorities have fallen fn with a suggestion to that
effect made to them by Sir Benjamin Stone, M.P. He offered a
series of one hundred platinotype prints of Westminster Abbey,
hoping that this would be the nucleus of a national photographic
record and survey collection, and the trustees of the British
Museum find themselves in full agreement with him, that such a
collection, if carefully and systematically brought together, could
not fail to be of the greatest value and interest. They have ex¬
pressed their willingness to take charge of such photographs as
may from time to time be deposited with them, and steps are
being taken to form a committee to organise the work.
The Royal Institution lectures will be resumed next week,
and on Friday, April 30, Professor J. J. Thomson will discourse
upon the cathode rays. The subsequent Friday evening lectures
will be on “Romance,” by Anthony Hope ; “ Explosion Flames,”
by Professor Harold Dixon; “Contact Electricity of Metals,” by
Lord Kelvin ; “ The Isolation of Fluorine,” by Professor Moissan ;
“Signalling through Space without Wires,” by W. H. Preece ;
and “Diamonds,” by William Crookes. Professor Moissan’s
lecture will be illustrated with experiments and should prove
most attractive, but the whole programme is excellent. Professor
Dewar will give three lectures on Thursday afternoons, on liquid
air as an agent of research.
The London Water Supply has, of course, been affected by
the continued rain of recent weeks. Dr. Frankland reports that
samples of Thames water examined by him were turbid and deep
yellow in colour, whiist bad in quality in respect to the presence
of bacteria and indifferent in chemical qualities. After storage and
filtration, however, the water was sent out of excellent quality,
and it would appear that the water companies have been put upon
their mettle by the action of the London County Council. The
abundant rainfall conduced to a diminution in the quantity of
water required, the daily supply during March being two and a
half million gallons less than in the corresponding month of the
preceding year. Nevertheless, the daily supply reached the
enormous total of 191,497,668 gallons.
The Naples Zoological Station celebrated its twenty-fifth
anniversary last week, and Professor Anton Dohrn, its founder
and director, has been privileged to see the indefatigable labours
of a quarter of a century crowned with astonishing success. Any
state, college, or scientific association can acquire the right to
retain a work-table at the Zoological Station, with the use of all
necessary apparatus and material, for an annual payment of fifty
pounds. Prussia has engaged four tables ; Saxony, Bavaria,
Wiirtemberg, Baden, Hesse, and Hamburg, one each. Oxford,
Cambridge, and the British Association also have tables, as well as
Italy, Austro-Hungary, Holland, Belgium, Switzerland, Roumania,
Bulgaria, and the United States. A small fleet of vessels is em¬
ployed to procure specimens for examination, and frequently as
many as forty students are engaged at the station at one and the
same time.
April 24, 1897]
PHARMACEUTICAL JOURNAL.
359
LITERARY NOTES.
‘ First Stage Inorganic Chemistry 5 by Dr. G. H. Bailey, is
a volume of “The Organized Science Series,” edited by Mr.
William Briggs. This series is devoted to the requirements of the
Science and Art Department, but for the sake of continuity
some of the subjects included in the present volume have been
rather more fully treated than the Department Syllabus demands,
and the book is probably the best systematic introduction to
chemistry yet published. It is intended to be used as a companion
in the laboratory and, like its predecessor — ‘ Tutorial Chemistry ’
— it bears internal evidence of having been written by a teacher
who thoroughly appreciates the difficulties experienced by elemen¬
tary students. The book is published by W. B. Clive, 13, Book¬
sellers’ Row, Strand, W.C., at two shillings, and is very cheap at
the price.
Formulaire des Medicaments Nouveaux for 1897 will be
welcomed by everyone who has grown accustomed to depend upon
this useful little work of reference. The editor, M. H. Bocquillon
Limousin, has done his work in his usual excellent style, and
pharmacists who require information respecting the newer
remedies and fail to find it in the standard works on materia
medica may often turn to this compilation with advantage.
Amongst the monographs in the present edition which may be
mentioned are those treating of actol, airol, amygdophenin, antinosin,
apolysin , argonin, benzacetin, bismal, caffeine, caffeinate of iron,
chlorcdose, citrophene, cocaine, cuprohemol, eosote, eucaine, eudoxine,
ferripyrine, ferrostyptin, gallicin, gelante, glutol, glycerophosphates,
hemogallol, hemol, hypnone, icthyol, iodoformin, itrol, kola,
lysidin, myronin , nosophene, nutrose, orphol, phosphergot, piperosine,
pixol, protogene, pyrantine, quinosol, salantol, salithymol, salopliene,
sanoform, somatose, sublimophenol, tannalbin, tannoform, tannigen,
trionaZ, thiosinnamine, urotropine, xeroform, and a large number of
colonial and foreign plants introduced recently into medicine.
The book is published by Messrs. J. B. Bailli^re et fils, 15, rue
Hautefeuille, Paris, at three francs.
“ Knowledge” for the current month contains much that will
attract those who are interested in the study of natural science.
An address by Professor Thorpe on the progress of chemistry
during the Queen’s reign finds a place, in addition to articles on
geological, botanical, and astronomical subjects, whilst natural
history is not neglected, and minor topics of interest have corners
devoted to them.
The Greater Celandine and its medicinal applications form the
subject of an article by Dr. John Knott, in the Medical Press for
April 14. He discusses the botanic and therapeutic history of the
plant, and quotes what is said concerning it by Dioscorides,
Matthiolus, Gerard, and Salmon, concluding by expressing a
hope that the plant may receive another trial as a medicinal agent.
‘ Guy’s Hospital Reports ’ for the past year give particulars of
a number of interesting cases, preceded by a capital memoir of the
late Arthur Edward Durham, by W. H. A. Jacobson, which is illus¬
trated by a fine portrait. A very marked feature in Durham’s
character was his optimism, and we are told that he was always
trying to make the best of everyone, to put the best constructions
on a man’s actions, to believe in and to teach how much kindness
there is in the world. “ A harsh or unkind word never fell from
Durham’s lips, and a bitter one very rarely, save in the case of some
flagrant charlatanism or knavery.” With regard to his brother
surgeons, no man was ever more free from all jealousy towards
those who might be considered his rivals, and, here as elsewhere,
Durham’s was no mere flaccid, passive good- nature, but a cordial,
genial goodwill.
“ Science Progress ” for April is in great measure devoted to
botanical topics. Professor Marshall Ward commences with an
article “On the Physiology of Reproduction in Plants”; C. A.
Barber discusses “The Diseases of the Sugar-Cane”; and Pro¬
fessor Reynolds Green summarises what is known and surmised
respecting the cell-membrane. Continued articles are those on
“Condensation and Critical Phenomena,” by Professor Kuenen,
and on “ The Coagulation of the Blood,” by Professor Halliburton.
A brief account of the Galeodidae is contributed by H. M. Bernard,
the relation between the form and metabolism of the cell is con¬
sidered by Dr. Max Verworn, and most attractive of all perhaps is
an account by Professor Poulton of a remarkable anticipation of
modern views of evolution.
Startin’s ‘ Skin Pharmacopceia,’ which is now in its fourth
edition, contains concise formulas for baths, mixtures, ointments,
lotions, and caustics, together with rules of diet, a classification
of skin diseases, and a therapeutic index. The book is published
for the use of students and medical practitioners engaged in active
practice, and within its fifty pages pharmacists may find much to
interest them. Messrs. John Wright and Co. of Bristol, are the
publishers, and the price is half-a-crown.
E. Merck’s Annual Report for 1896 (Darmstadt) contains a
note on the purification and composition of pilocarpidine, and
particulars regarding such preparations as kakodylic acid and its
sodium salt, peronine, picronitric acid, actol or silver lactate,
amylum iodatum insolubile, amyloform, apiolinum, salts of
arecoline, aurum metallicum granulatum for Jolles’s
method, bismuth tribromophenate, borol, calcium carbide,
crystallised calcium tungstate, for X ray experiments, salts of
chelidonine, quinaphthol, quinosol, chrysoidine, erythroli tetra-
nitras, eucasin, new extracts of various kinds, including extract
of leeches, geosot, or guaiacol valerianate, glutol, guaetliol,
halogen- and metal-hasmols ; and a large number of other medica¬
ments of recent introduction.
Viola Tricolor, L., is the subject of the inaugural dissertation
that was presented to the philosophical faculty of the University
of Marburg by Dr. Henry Kraemer, of Chicago, U.S.A., on the
occasion of taking his degree. The morphology, anatomy, and
biology of the plant are considered at length, and the monograph,
which occupies some seventy quarto pages, is illustrated by five
plates, containing seventy-two carefully executed figures.
“ The International Journal of Microscopy and Natural
Science,” which is published quarterly, is perhaps not so well
known as it deserves to be. It is the organ of the Postal Micro¬
scopical Society, each member of which receives a copy as
published, but it may also be obtained by anyone who chooses to
subscribe half-a.-guinea per annum. In the April number appear
articles on light and colour, the Californian trap-door spider, the
planet Mars, staining tubercle bacilli in sections, a rapid method
of preparing permanent sections for microscopical diagnosis, and
numerous notes on microscopical technique and matters of
interest from a natural history point of view. The London
publishers of the Journal are Messrs. Balliere, Tindall, and Cox,
20, King William Street, Strand,
360
PHARMACEUTICAL JOURNAL.
[April 24, 1897 .
BRITISH ASSOCIATION FOR THE
ADVANCEMENT OF SCIENCE.
— - 4- - -
BOTANICAL SECTION.
OPENING ADDRESS BY
D. H. SCOTT, M.A., Ph.d , F.R.S.
Honorary Keeper of the Jodrell Laboratory , Royal Gardens, Kew,
President of the Section.
THE PRESENT POSITION OF MORPHOLOGICAL BOTANY
( Continued from page 37. )
Relation between Mosses and Ferns.
Goebel said, in 1882 : “ The gap between the Bryophyta and the
Pteridophyta is the deepest known to us in the vegetable kingdom.
We must seek the starting-point of the Pteridophyta elsewhere
than among the Muscineae : among forms which may have been
similar to liverworts, but in which the asexual generations entered
from the first on a different course of development.”* I cannot
help feeling that all the work which has been done since goes to
confirm this wise conclusion. Attempts have been made in the
most sportsman-like manner (to adopt a phrase of Professor
Bower’s) to effect a passage over the gulf, but the gulf is still
unbridged. I cannot see anywhere the slightest indication of any¬
thing like an intermediate form between the spore-bearing plant of
the Pteridophyta and the spore-bearing fruit of the Bryophyta.
The plant of the Pteridophyta is sometimes small and simple, but
the smallest and simplest seem just as unlike a bryophytic sporo-
gonium as the largest and most complex. On the side of the moss
group, Anthoceros has been often cited as a form showing a certain
approach towards the Pteridophytes, and Professor Campbell in
particular has developed this idea with remarkable ingenuity.
An unprejudiced comparison, however, seems to me to show
nothing more here than a very remote parallelism, not suggestive
of affinity.
There is no reason to believe that the Bryophyta, as we know
them, were the precursors of the vascular Cryptogams at all.
There is a remarkable paucity of evidence for the geological
antiquity of Bryophyta, though many of the mosses at any rate
would seem likely to have been preserved if they existed.
Brongniart said, in 1849, “ The rarity of fossil mosses, and their
complete absence up to now in the ancient strata, are among the
most singular facts in geological botany ” ;+ and since that time it
is wonderful how little has been added. Things seem to point to
both Pteridophyta and Bryophyta having had their origin far back
among some unknown tribes of the Algae. If we accept the homo¬
logous theory of alternation, we may fairly suppose that the
sporophyte of the earliest Pteridophyta always possessed vegetative
organs of some kind. The resemblance between the young sporo¬
phyte and the prothallus in some lycopods indicates that at some
remote period the two generations may not have been very dis¬
similar. At least some such idea gives more satisfaction to my
mind than the attempt to conceive of a fern-plant as derived from
a sterilised group of potential spores.
The Bryophyta may have had from the first a more reduced
sporophyte, the first neutral generation having, in their ancestors,
become more exclusively adapted to spore-producing functions. I
must not omit to mention the idea that the Bryophyta, or at any
rate the true mosses, are degenerate descendants of higher forms.
The presence of typical stomata on the capsule in some cases, and
of somewhat reduced stomata in others, has been urged in support
of this view. It is possible ; but if so, from what have these plants
been reduced ?
Few people, perhaps, fully realise how absolutely insoluble such
a problem as we have been discussing really is. I say nothing as to
the mosses, which may have arisen relatively late in geological
history. The Pteridophyta, at any rate, are known to be of in¬
conceivable antiquity. Not only did they exist in greater develop¬
ment than at present in the far-off Devonian period, but at that
time they were already accompanied by highly organised gymno-
spermous flowering plants. Probably we are all agreed that
Gymnosperms arose somehow from the vascular Cryptogams.
Hence, in the Devonian epoch, there had already been time not
only for the Pteridophyta themselves to attain their full develop¬
ment, but for certain among them to become modified into complex
Phanerogams. It would not be a rash assumption that the origin
of the Pteridophyta took place as long before the period represented
by the plant-bearing Devonian strata as that period is before our
own day. Can we hope that a mystery buried so far back in the
dumb past will be revealed ?
It will be understood that I do not wish to assume the role of
partisan for the homologous theory of alternation. Possibly the
whole question lies beyond human ken, and partisanship would be
ridiculous. But I do wish to raise a protest against anything like
a dogmatic statement that alternation of generations must have
been the result of the interpolation of a new stage in the life-
history. Let us, in the presence of the greatest mystery in the
morphology of plants, at least keep an open mind, and not tie
ourselves down to assumptions, though we may use them as
working hypotheses.
Histological Characters of the two Generations.
There is one histological question upon which I must briefly
touch because it bears directly on the subject which we have been
considering.
It is now well known that in animals and in the higher plants a
remarkable numerical change takes place in the constituents of the
nucleus shortly before the act of fertilisation. The change consists
in the halving of the number of chromosomes, those rod-like bodies
which form the essential part of the nucleus, and are regarded
by Weismann and most biologists as the bearers of hereditary
qualities. Thus in the lily the number of chromosomes in
the nuclei of vegetative cells is twenty-four ; in the sexual
nuclei, those of the male generative cell and of the ovum, the
number is twelve. When the sexual act is accomplished the two
nuclei unite, and so the full number is restored and persists
throughout the vegetative life of the next generation. The abso¬
lute figures are of course of no importance ; the point is, the reduc¬
tion to one half during the maturation of the sexual cells, and the
subsequent restoration of the full number when their union takes
place. I say nothing as to the details or the significance of the
process, points which have been fully dealt with elsewhere, notably
in an elaborate recent paper by Miss E. Sargant.
- Now, in animals (so far as I am aware) and in angiospermous
lants the reduction of the chromosomes takes place very shortly
efore the differentiation of the sexual cells. Thus in a lily the
reduction takes place on the male side immediately prior to the
first division of the pollen mother-cell, so that four cell-divisions in
all intervene between the reduction and the final differentiation of
the male generative cells. On the female side the reduction in the
same plant takes place in the primary nucleus of the embryo-sac,
so that here there are three divisions between the reduction and
the formation of the ovum. I believe these facts agree very closely
with those observed in the animal kingdom, and so far there is no
particular difficulty, for we can easily understand that if the
number of chromosomes is to be kept constant from one generation
to another, then the doubling involved in sexual fusion must
necessarily be balanced by a halving.
There are, however, a certain number of observations on
Gymnosperms and archegoniate Cryptogams which appear to put
the matter in a different light. Overton* first showed that in a
Cycad, Ceratozamia, the nuclei of the prothallus or endosperm all
have the half-number of chromosomes. Here then the reduction
takes place in the embryo-sac (or rather its mother-cell), but a
great number of cell-generations intervene between the reduction
and the maturation of the ovum. In fact the whole female oophyte
shows the reduced number, while the sporophyte has the full
number. The reduction takes place also in the pollen mother-cell.
Further observations have extended this conclusion to some other
Gymnosperms.
In Osmunda among the ferns there is evidence to show that
reduction takes place in the spore mother-cell, and that the sexual
generation has the half-number throughout. Professor Farmer has
found the same thing in various liverworts, and shown that the
reduction of chromosomes takes place in the spore mother-cell ; and
his observations of cell-division in the two generations have afforded
some direct evidence that the oophyte has the half-number and the
sporophyte the full number throughout. Professor Strasburger
* Schenk's ‘ Handbuch der Botanik,’ vol. ii. , p. 401.
‘ Tableau des Genres de Yegetaux Fossiles,’ p. 13-
* ‘ Annals of Botany,’ vol. vii., p. 139,
Apbil 24, 1897]
PHARMACEUTICAL JOURNAL.
361
fully discussed this subject before Section D at Oxford,* and came
to the conclusion that the difference in number of chromosomes is
a difference between the two generations as such, the sexual
generation being characterised by the half-number, the asexual by
the full number.
The importance of this conception for the morphologist is that
an actual histological difference appears to be established between
the two generations ; a fact which would appear to militate against
their homology. Some botanists even go so far as to propose
making the number of chromosomes the criterion by which the
two generations are to be distinguished. Considering that the
whole theory rests at present on but few observations, I venture to
think this both premature and objectionable ; for nothing can be
worse for the true progress of science than to rush hastily to
deductive reasoning from imperfectly established premises.
The facts are certainly very difficult to interpret. Those who
accept the antithetic theory of alternation suppose the sexual
generation to be the older, and that in Thallophytes the plant is
always an oophyte, whether “actual” or “potential.” Hence
they believe that in Thallophytes the plant should show through¬
out the reduced number of chromosomes, reduction hypothetically
taking place immediately upon the germination of the oospore. If
this were true it would lend some support to the idea of the inter¬
calation of the sporophyte, but at present there is not the slightest
evidence for these assumptions. On the contrary, in the only
Thallophyte in which chromosome-counting has been successfully
accomplished (Fucus), Professor Farmer and Mr. Williams find
exactly the reverse ; the plant has throughout the full number of
chromosomes ; reduction first takes place in the oogonium, imme¬
diately before the maturation of the ova, and on sexual fusion the
full number is restored, to persist throughout the vegetative life of
the plant. Fucus is, no doubt, a long way off the direct line of
descent of Archegoniatae, but still it is a striking fact that the
only direct evidence we have goes dead against the idea that the
sexual generation (and who could call a Fucus-plant anything else
but sexual ?) necessarily has the reduced number of chromosomes.
This fact is indeed a rude rebuff to deductive morphology.
I am disposed to regard the different number of chromosomes in
the two generations observed in certain cases among Archegoniatae
not as a primitive but as an acquired phenomenon, perhaps cor¬
related with the definiteness of alternation in the Archegoniatae as
contrasted with its indefiniteness in Thallophytes. In Fucus, in
flowering plants, and in animals the soma or vegetative body has
the full number of chromosomes. With these the sporophyte of the
Archegoniatse agrees ; it is the oophyte which appears to be
peculiar in possessing the half-number, so that if the evidence
points to intercalation at all, it would seem to suggest that the
oophyte is the intercalated generation — obviously a reductio ad,
absurdum. I do not think we are as yet in a position to draw any
morphological conclusions from these minute histological
differences, interesting as they are.
The question how the number of chromosomes is kept right in
cases of apospory and of apogamy is obviously one of great interest,
and I am glad to say that it is receiving attention from competent
observers.
Sexuality of Fungi.
Only a few years ago De Bary’s opinion that the fruit of the
ascus-bearing Fungi is normally the result of an act of fertilisation
was almost universally accepted, especially in this country.
Although the presence of sexual organs had only been recorded in
comparatively few cases, and the evidence for their functional
activity was even more limited, yet the conviction prevailed that
the ascocarp is at least the homologue of a sexually produced fruit.
The organ giving rise to the ascus or asci was looked upon as
homologous with the oogonium of the Peronosporeae, the supposed
fertilising organ either taking the form of an antheridial branch as
in that group, or, as observed by Stahl in the lichen Collema,
giving rise to distinct male cells, or spermatia. More recently
there has been a complete revolution of opinion on this point, and
a year ago or less most botanists probably agreed that the question
of the sexuality of the Ascomycetes had been settled in a negative
sense. This change was due, in the first place, to the influence of
Brefeld, who showed, in a great number of laborious investiga¬
tions, that the ascus-fruit may develop without the presence of
anything like sexual organs ; while Mbller proved that the sup¬
posed male cells of lichens are in a multitude of cases nothing but
conidia, capable of independent germination.
The view thus gained ground that all the higher Fungi are
asexual plants, fertilisation only occurring in the lower forms, such
as the Peronosporese and Mucorinese, which have not diverged far
from the algal stock. The ascus, in particular, is regarded by this
school as homologous with the asexual sporangium of a Awcor.
This theory has been brilliantly expounded in a remarkable book
by Von Tavel, which we cannot but admire as a model of clear
morphological reasoning, whether its conclusions be ultimately
adopted or not.
Still, it must be admitted that the Brefeld school were rather apt
to ignore such pieces of evidence as militated against their views,
and consequently their position was insecure so long as these
hostile posts were left uncaptured.
Quite recently the whole question has been re-opened by the
striking observations of Mr. Harper, an American botanist working
at Bonn.
Zopf, in 1890,* pointed out that up to that time it had not been
possible in any Ascomycete to demonstrate a true process of ferti¬
lisation by strictly scientific evidence, namely, by observing the
fusion of the nuclei of the male and female elements. Exactly the
proof demanded has now been afforded by Mr. Harper’s observa¬
tions, for in a simple Ascomycete, Sphcerotheca castagnei, the para¬
site causing the hop-mildew, he has demonstrated in a manner
which appears to be conclusive the fusion of the nucleus of the
antheridium with that of the ascogonium.t It is impossible to
evade the force of this evidence, for the fungus in question is a
perfectly typical Ascomycete, though exceptionally simple, in so
far as only a single ascus is normally produced from the ascogo-
nium. It is unnecessary to point out how important it is that Mr.
Harper’s observations should be confirmed and extended to other
and more complex members of the order. In the meantime the
few who (unlike your President) had not bowed the knee to Brefeld
may rejoice !
It is impossible to pursue the various questions which press upon
one’s mind in considering the morphology of the Fungi. The
occurrence not only of cell-fusion, but of nuclear fusion, apart
from any definite sexual process, now recorded in several groups of
Fungi, urgently demands further inquiry. Such unions of nuclei
have been observed in the basidia of Agarics, the teleutospores of
"Uredinese, and even in the asci of the Ascomycetes. That such a
fusion is not necessarily, as DangeardJ has supposed, of a sexual
nature, seems to be proved by the fact that it occurs in the young
ascus of Sphccrotheca long after the true act of fertilisation has
been accomplished. It is possible, however, that these phenomena
may throw an important side-light on the significance of the sexual
act itself.
Another question which is dbviously opened up by the new results
is that of the homologies of the ascus. The observations of
Lagerheim§ on Dipodascus point to the sexual origin of a many-
spored sporangium not definitely characterised as an ascus. On
the other hand, not only sporangia, but true asci are known to
arise in a multitude of cases direct from the mycelium. It is of
course possible that as regards the asci these are cases of reduction
or apogamy ; on the other hand, it is not wholly impossible that
the asci may turn out to be really homologous with a sexual
sporangia, even though their development may often have become
associated with the occurrence of a sexual act. However this may
be, there is at present no reason to doubt that a very large propor¬
tion of the Fungi are, at least functionally, sexless plants.
( To be continued. )
Thymol in Pertussis. — Josias, in his new work ‘ Therapeutique
Infantile,’ recommends the use of thymol instead of carbolic acid
as a spray in this disease. A vessel containing the following solu¬
tion is placed over a small night lamp in the room and allowed to
evaporate : — Thymol, 10 grammes ; alcohol, 300 grammes ; water,
700 grammes. At the Trousseau Hospital an alcoholic solution of
thymol and menthol is used several times a day for spraying the
rooms reserved for whooping cough cases. A vapour-atomiser with
the following formula is employed : — Thymol, 6 grammes ;
menthol, 6 grammes ; alcohol, 90°, 120 grammes. A tablespoonful
in the atomiser, which has been previously filled with water. —
Pediatrics, iii. , 48, after Univers. M. J., 1896, x., 303.
* “Die Pilze,’’ Schenk’s ‘ Handbuch der Botanik,’ Bd. iv. , p. 341.
t ‘ Berichte der deutschenbot.GesellEchaft,’ yol. xiii., January 29, 1896.
t Le Botaniste, vols. iv. and v.
Pringsheim’s ‘ Jahrbuch f. Wiss. Bot ,’ 1892,
* See ‘ Annals of Botany,’ vol. viii., p. 281.
362
PHARMACEUTICAL JOURNAL.
[April 24, 1897
THE WORLD Op PHARMACY.
— - ♦ - -
BUSINESS MEETINGS.
Plymouth, Devonport, Stonehouse and District
Chemists’ Association, Wednesday, April 14. — Mr. G. Breeze,
President, in the chair. — The quarterly meeting of the above was held
at the Foresters’ Hall ; among those present being Messrs. A. D.
Breeze, C. J. Park, Jas. Cocks (Hon. Sec.),0. A. Reade, F. W. Hunt,
J. I). Turney, J. Barge, J. R. Johnson, H. Yibert Reynolds, W.
H. Woods, Condy U’Ren, C. T. Weary, Kelly. The minutes
having been passed, Mr. Foster, junr. , was elected a member,
which now brings the membership up to 131. — Mr. Hunt proposed
and Mr. Barge seconded the following resolution, passed at the
General Committee : —
“ That this Committee recommends the Association to adopt Mr. Park as
candidate at the coming Pharmaceutical Council Election, and to use their
best efforts to ensure his being elected,”
which was carried unanimously. A lengthy discussion took place
on the
New Bye-Laws
as proposed by the Pharmaceutical Society. — Mr. Cocks asked
whether there was any truth in the statement that the new fees were
required to wipe out a deficit caused by the expenses of the Pharma¬
ceutical Journal. — In answer to Mr. Cocks’ enquiry if the increased
fees for examination and registration were required, as had been
stated, to carry on the Pharmaceutical Journal at a loss, Mr. Park
repudiated the idea, and referred those present who had not already
read it to the editorial in the Pharmaceutical Journal of March 20.
He was very glad to have heard so many warm expressions of-
approval passed by members of their local association on the
Pharmaceutical Journal as now conducted, both from a trade and
educational point of view. He would like to point out that
the Journal was not run on purely commercial lines
only. What he meant was, that it was not con-'
ducted with the main object of making a good return
financially for the money expended in its production. It was to a
large extent educational, and the argument that had been
used against the Journal might be equally applied to the
School of Pharmacy by everyone who nad a monetary interest
in schools for pharmaceutical education. The Journal was
conducted in the best interests of the whole of the craft. They,
as business men, could easily conceive that advertisements might
be offered on certain conditions that would materially swell the
revenue of the Journal, but would lower its standard,
compromise its supporters, and probably mislead its readers.
With regard to the increased expenditure of recent years, they
had proofs of its expediency and wisdom in every issue of the
present Journal. That expenditure had been and was at
the present time being recouped in an eminently satisfactory
manner by the revenue received from advertisements and by the
great satisfaction afforded to readers. In conclusion, he pointed out
that their interest as pharmacists and that of the Pharmaceutical
Journal should be identical, since the supporters of the Pharma¬
ceutical Society were in fact its proprietors, and it was for them alone
to say whether they were satisfied with the manner in which it
was conducted. He hoped that all supporters of the Society
would endeavour to push the interests of their own property and
make it as great a success financially as it undoubtedly was from a
literary point of view. He saw no reason why it should not become
a source of handsome revenue to the Society, but whether its suc¬
cess financially was great or small, it was imperative that they
should have an official organ to represent British pharmacy and
its interests conducted independently of outside interests. — Mr.
Cocks moved, and Mr. Turney seconded : —
“That this Association approves of the new Bye-laws as proposed by the
Pharmaceutical Council, and considers that they are desirable, both in the
interest of the public, and those engaged in the business.”
Mr. Barge moved as an amendment : —
“ That the year when the increase in the fees for the Minor examination should
come into force should be altered from January, 1899, to January, 1900.”
The resolution was carried, Mr. Barge being the only dissentient.
Report of Educational Committee.
The report of the Educational Committee was read by Mr. J. R.
Johnson (Secretary), who reported that examinations in pharmacy
and pharmaceutical Latin, conducted by Professor Greenish, were
to be held on W ednesday and Thursday evenings, the 28th and 29th
of this month, from 6.30 to 8 p.m., when prizes were recommended
to be awarded. Owing to the success of the botanical rambles
last year, it was decided to arrange a similar course for the ensuing
ear subject to a slight alteration. Once a fortnight there would
e in the evening lectures on morphology and classification of
plants, the other week in the afternoon botanical rambles.
The Committee submit that the small fee of 2s. be
charged for the course of lectures and rambles. Mr.
Reade has kindly consented to conduct the class. They
also recommend that prizes be awarded for the best herbaria.
For the next winter session they recommend that classes be con¬
ducted under the auspices of the Association in pharmacy and
materia medica, with the subsidiary subject of prescription Latin,
the same arranged in two classes, (a) pharmacy, (b) materia
medica and prescription Latin, and, if found necessary, each of
these to be sub-divided into two classes, elementary and advanced.
That the fees shall be, for the course (elementary or advanced) in
one subject, 4s. ; for the course (elementary or advanced), in both
subjects, 7s. 6 d. ; and that examinations be held at the close of
the session, prizes being awarded as heretofore. — The report
was adopted and carried unanimously. — Mr. Cocks (Secretary)
reported that the committee appointed to find new rooms
had taken rooms at 7, Whimple Street, Plymouth, and suggested
that as £20 would be required to furnish the rooms, it should be
raised in the following manner, in 20 £1 shares payable at
5 per cent, interest, a certain amount to be repaid every year.
The following Committee were appointed to raise the £20 and
superintend the furnishing of the rooms Messrs. Weary, Condy
U’Ren, Woods, Reade, Swainson, J. Cocks, C. J. Park, G. Breeze,
J. H. Bailey (Hon. Secretary).
Aberdeen and North of Scotland Society of Chemists
and Druggists, Wednesday, April 14. — Mr. Johnston, Presi¬
dent, in the chair. — A special meeting was held in the Society’s
rooms. After the ordinary business of the Society was transacted,
Mr. Craig submitted the following motion
“That the members of the Aberdeen and North of Scotland Society of Che¬
mists and Druggists at this meeting, convened for the discussion of the pro¬
posed new bye-laws of the Pharmaceutical Society, wish to express their
disapprobation of the attempt of the Society to raise the fee of the Minor
examination to £10 10s.”
He said that only two reasons can be given for the increased fee :
1st, increase of funds that would be brought in ; 2nd, by possibly
reducing the number of chemists, and thereby improving their
status. With regard to the first reason, he considered that the
examinations did pay, and adduced figures to prove fiis conten¬
tion. He said the Pharmaceutical Journal swallowed up the funds,
and contended that the Society had no right to make candidates
pay for a journal that was supplied to members of the Society,
and that the Journal should be placed on the same footing as other
journals, that is, let those who want it subscribe for it as a journal.
With regard to the second reason for alteration, he did not think
it would improve the condition of the chemist. It would put a
number of unqualified men in competition with qualified men as
assistants, and thereby reduce wages. — Mr. Urquhart seconded
the motion, and Mr. Bruce supported it. — Mr. John Cruickshank,
Hon. Secretary, proposed as an amendment : —
“ That the Aberdeen and North of Scotland Society of Chemists and Druggists
support the action of the Council of the Pharmaceutical Society in framing
the new bye-laws."
He said that even if Mr.' Craig’s contention were true, that the
Pharmaceutical Journal swallowed up the funds of the Society, was
it not the case that the improved Journal was found necessary,
owing to the chemists throughout the country insisting that it
should be conducted less scientifically and should take up trade
interests more ? Chemists both in and out of the Society had also
occasionally clamoured for more prosecutions against unqualified
traders. This had been taken up most vigorously by the Society,
and recently a number of prosecutions had taken place in Scot¬
land, but the paltry sums recovered as fines were quite inadequate
to meet the large outlays. Then how was the expenditure to be
met when so many remained outside the Society and subscribed not
April 24, 1897]
PHARMACEUTICAL JOURNAL.
363
a farthing to its funds ? — Mr. Clark, pharmaceutical chemist,
seconded the amendment and Mr. Ritchie supported it. — The
vote was taken, when there voted for Mr. Cruickshank’s amend¬
ment eight, and for Mr. Craig’s motion four.
SOCIAL MEETINGS,
Bradford and District Chemists’ Association, Wed¬
nesday, April 7. — -The President, Mr. E. Mackay, in the chair. — -
The members of the above Association, together with their wives
and friends, had a very enjoyable evening on the occasion of their
annual conversazione, which were held at the Great Northern
Victoria Hotel. During the evening some very entertaining exhibits
were shown, including the Rontgen rays, by Messrs. Reynolds and
Branson, of Leeds, a six-inch spark coil being used. Explanations
were given of the four Guisley tubes of various vacuums, fluores¬
cent cross (Crookes’ tube), rubies and shells (cathode tube), and the
X rays focus tubes, showing rings on the finger, coins, etc., in
purses, bones in the hand, etc. Soap bubbles, by Mr. J. E. Wilson,
of Bradford, proved very interesting, and electrical clocks were
shown by Mr. T. H. Pattinson. Agreeable musical selections
were contributed at intervals by Mr. and Mrs. J. A. Mitchell, Mr.
and Mrs. J. Moulson, and Miss Mackay. The conversazione was
a great success, and was thoroughly enjoyed. — At the close of the
evening Mr. Mackay proposed a vote of thanks to the ladies and
artistes, which was carried unanimously.
Liverpool Pharmaceutical Students’ Society, Wednes¬
day, April 14. — Mr. John Jones, President, in the chair.— A very
successful session was brought to a close by a smoking concert, held at
the Kardomah Cafe, Church Street, Liverpool. A company of some
forty members and their friends was present, for whose entertain¬
ment a lengthy programme of vocal and instrumental music was
submitted, the artistes comprising members of the Society and
numerous talented friends, and the items being, without excep¬
tion, of a much higher class than is usual at such gatherings. Songs
were rendered by Messrs. Shacklady, W. J. Barlow, Field, Percy
Stone, Will Hyde, and Burgess, the humorous element being pro¬
vided by Will Hyde in the shape of a sketch upon “ Nothing” and
several songs by Mr. Burgess, whoseamusing patter was of a decidedly
original description. Solos and duets were contributed on the banjo
(by Mr. Thoms), piano (Mr. Hughes), violin (Mr. Burgess), and flute
(by Mr. Cook) in good style and to the evident appreciation of a
somewhat critical audience. During the evening an appeal was
made to the members on behalf of the Benevolent Fund of the
Pharmaceutical Society by the Vice-President, Mr. T. S. Wokes,
supported by Mr. R. H. Mitchell, and a collection was taken up
amounting to £2 5s. 4 d. , the largest amount so far received at such
social meetings held by the “students.” In proposing a vote of
thanks to the artistes, Mr. Shacklady eulogised the President,
Secretary, and artistes for the splendid exhibition of talent they
had enabled their audience to enjoy, and stated that in his opinion
the concert was the most successful from a music point of view that
the students had ever held, the quality of the songs and instru¬
mental pieces being of a very high standard indeed, and the comic
songs being really of a humorous character and not partaking of
the too prevalent vulgar music-hall inanity.
LEGAL INTELLIGENCE.
PROCEEDINGS UNDER THE FOOD AND DRUGS ACTS.
The Sale of Glycerin and Lime Juice.
On Saturday, at Brentford Police Court, before Mr. M. Sharpe,
Chairman, and a full Bench, Mr. James Wilkey Webber, pharmaceu¬
tical chemist, of 202, High Road, Chiswick, W., appeared to an
adjourned summons for having sold glycerin and lime cream not
of the nature, substance and quality demanded by Walter Tyler,
an inspector under the Food and Drugs Act.
Mr. G. W. Lay again defended.
As the case stood, the prosecution relied on the certificate of
Mr. E. Bevan, the official county analyst, which stated there
was no glycerin in the compound. The defence was that there
was glycerin present to the extent of half a drachm to 8 ozs.,
and the case was adjourned in order that the Somerset House
authorities might analyse a portion of the sample.
The Clerk of the Court read the Somerset House certificate,
which stated that the sample was found to contain a mixture of
mineral and vegetable oils, sugar, lime water, and glycerin, the
last-named ingredient to the extent of half a fluid drachm to 8 ozs.
of the mixture. This was signed by Messrs. R. Bannister, F.I.C.,
F.C.S., andG. Lewin, F.I.C.
Mr. Lay submitted that, upon this certificate, he was entitled to
a dismissal of the summons. At the previous hearing he called the
defendant and the actual maker of the compound, who deposed
that glycerin was put into it to the extent of half a drachm to the
8-oz. bottle. The Somerset House certificate corroborated this,
and taken together this evidence disproved any fraud on the part
of the defendant.
The Clerk of the Court interposing, stated that the Court was not
bound by the Somerset House analysis.
The Chairman said that the certificates were very wide apart
indeed, and it would be only fair to the county analyst to hear if
he wished to make any observations.
Mr. Bevan informed the Court that he could not accept the cer¬
tificate from Somerset House. He had also fortified himself with
the opinion of a very expert analyst, who bore out his investi¬
gation.
Mr. Lay said that he had also had the sample analysed indepen¬
dently, and his certificate agreed with Somerset House. All the
facts were in favour of the defendant.
The Justices conferred, and the Chairman stated that as the
matter was so important in the interests of the county and the
official analyst, that it could not be allowed to rest where it was. The
certificates from Somerset House were so much waste paper without
being supported by evidence, and the Court considered that the
two gentlemen who signed it should attend, in order that they
might be cross-examined. They, as Justices, could not tell which
was right, and the divergence was so great and so vital to the
case that all the circumstances must be closely investigated before
a just decision could be arrived at. The cost would not fall on
the defendant. The matter was one which concerned the county,
and it should be seen who was right.
The summons was adjourned accordingly.
NEW REMEDIES.
Holzinol. — This specialty, brought forward as a remedy for
whooping cough, is said to consist of formic aldehyde, 2 ; menthol, 40 ;
methylic alcohol, 58. — Pharm. Ze.it., xlvi., 672.
Resorcin in Seborrhea Capitis.— Resorcin, 1 ; spts. vini
rect., 50; petrolati, 150. Sig. — -external use. The liniment is
to be rubbed into the hairy scalp on going to bed. Later on the
application is made only every other day. — Pediatrics, iii. , 60.
Ichthyol in Conjunctival Eczema. — Ammon, sulphoichthyolat,
0'5 ; amyli tritici, zinci oxyd. aa, 10 ; petrolali, 25 ; ft. ungt.
Sig. — to be rubbed into the eyelids at night and covered with zinc
ichthyol ointment. — Pediatrics, iii., 61, after Zeitschr. f. Krau-
Renpflege, 1896, 8.
Airol in Leprosy. — A 10 per cent, ointment of airol with
vaseline applied daily with massage over the affected area, as well
as injections of 10 per cent, glycerin solutions of airol into the
deeper ulcers, enabled Fornara to greatly ameliorate a severe case
of leprosy ; the purulent abscesses healed, the conjunctiva}
became normal, and the hair which had dropped off reappeared. —
Nouv. Rem., xiii., 108.
Cerium Salts as Antiseptics. — The various compounds of
cerium and nitric acid are recommended for their active germi¬
cidal action, while they are non-poisonous towai’ds higher or¬
ganisms. The colourless cerium nitrate in a one per mille
solution prevent all bacterial growth, although a much stronger
solution has little or no action upon the wound tissues. Cerium
ammonio-nitrate forms red, easily decomposable, crystals, which
also prevent the growth of bacteria at 1:200. The nitrates of
didynium, lanthanium, yttrium, erbium, thorium, and zirkonium
show a similar .property. The chlorides and nitrates are easily
soluble in water, the sulphates are more difficult to dissolve, this
being specially the case with the double alkaline sulphates. The
carbonates, phosphates, and oxalates are quite insoluble. — -
Pharm. Post, xxx., 103.
364
PHARMACEUTICAL JOURNAL.
[April 24, 1897.
LETTERS TO THE EDITOR.
The Council Election.
Sir, — May I be allowed to add one word to the letters already
published with regard to the forthcoming Council election, par¬
ticularly with reference to the facts stated by Mr. Gostling and
Mr. Keen as to the very serious diminution in the proportion of
London pharmacists on the Council of the Society ? This diminish¬
ing proportion constitutes, in my opinion, a very grave anomaly,
to use no stronger expression, for it is altogether out of the ques¬
tion that one-fourth of the Council should be expected to do all
the Committee work in the interval between the monthly meetings,
while the other three-fourths get off “ scot-free,” as we say here.
It is well known to every person who has had any experience on a
public board that the stated public meetings are only a very small
part of the work, the Committee meetings always requiring much
more time and attention. On this ground alone it is a distinct
hardship that we should put upon the few London pharmacists
who give their time to the Society such an amount of hard
work as really makes the post of Councillor one to be
avoided rather than envied. We all recognise that the position
is one of honour, and for that reason we wish it occupied by
our best men, but these very men have their hands full already,
and it is not right to ask any one of them to make himself a slave
for the sake of the Society when a more judicious selection may
distribute the honours quite as deservedly, and ensure that no man
will be unduly burdened. On the ground of common humanity,
therefore, I would suggest that the Society should return a larger
proportion of London men than we have hitherto done. There is
another aspect of the case which should receive attention. Where
are our future Presidents to come from ? Of necessity these must
be London men, and they must be trained for the work. We
naturally look forward to a few years of our genial President, Mr.
Hills, and also to seeing Mr. Martindale, and Mr. Savory, and Mr.
Allen all filling the chair, but these gentlemen will be the first
to admit that it is only once a century or so that a Carteighe
appears, and probably none of us will live to see another President
with a record of anything like fourteen years. But if we do not
put new men forward where are we to find our Presidents in the
future ? This is an aspect of the case that deserves serious con¬
sideration. The only other point is one that some may think a
sordid one, viz., that of expense, but in these days, when retrench¬
ment is the order of the day, I see no reason why the Society
should not save a little here. Our country councillors are all most
excellent men, and they do good by their influence in the districts
they represent, but after all we may pay too dearly in more ways
than one, even for the moral influence of a councillor, particularly
when it is of so little service in a London committee meeting. On
these grounds, therefore, I consider there is ample justification in
asking the members of the Society to return a larger proportion of
London councillors than we have been doing in recent years.
Hawick, April 14, 1897. Thos. Maben.
The Proposed New Bye-Laws.
Sir, — The proposed alterations in the bye-laws are a step in the
right direction, especially the raising of the standard of the Pre¬
liminary examination, which at the present is inadequate. I think
the proposed increased fee for the Minor (or more properly the
qualifying examination) would receive more support provided one
more advantage could be gained, that is, all persons on passing
the Minor, and being placed on the Register, should be exempt
from jury service, as are medical men, pharmaceutical chemists,
and dentists. This would meet with general approval.
April 14, 1897. Associate (90/2).
*** What our correspondent suggests, though extremely desirable, cannot be
realised without obtaining fresh Parliamentary powers.— [Ed. Ph. J.]
The Latin oe Pharmacy.
Sir, — Mr. Ince, in his almost apologetic paper on the latinity of
pharmacy, which constrains one’s interest, leaves to botanical
authorities to decide — not a question of latinity for which they are
not competent but— whether they will use the word ‘ ‘ silvestris ”
or “ sylvestris.” It is to be feared that classically there is not much
choice — “the i’s have it,” as Mr. Speaker says. Still one may nourish
a little heresy and side with the “ most eminent botanists ” on the
ground that, as Latin appeals to our eyes rather than our ears,
“ sylvestris ” preserves to us more of the Greek v\tj than the more
usual “ silvestris.” Indeed one might suppose that some “ Eizak Pit¬
man ” of the period had caught the ear of the learned at Rome when
“silvestris” was accepted by its writers. I look forward with
interest to further contributions from Messrs. Ince and Coull, but
I doubt whether they or any other authorities will effect uni¬
formity among “ students ” in the pronunciation of such words as
“ conium” and “barium,” for the Hellenes in one case are Philis¬
tines in the other. It is, however, highly desirable that persons in
authority in pharmacy should maintain the right standard, though
there may be no power to enforce it just yet. ‘ ‘ Higher education,” a
watchword of to-day, tends in the right direction. What militates
powerfully against correct utterance is the fact that paper work
almost excludes oral instruction, and the ear of the student is in
subjection to the eye for purposes of education. The utterances
of even distinguished professors occasionally shock the ear. I
presume it is pure “ cussedness ” which makes “students” say
“camphora,” and not a foolish affection for icdipovpa.
Ryde, April 19, 1897. Henry H. Pollard.
An Assistants’ Qualification Wanted.
Sir, — I am pleased to see that in Mr. McMillan has come forward
the champion of true pharmacy, for Avhom I have been hoping
these two years or more. Over and over again have I been on the
point of writing to protest against the more or less uselessness for
trade purposes of the present system of examination for the
Minor and Major. The Pharmaceutical Society educates a man
in its own School at considerable expense to himself, then charges
him a heavy fee for examination, and if he be sufficiently fortunate
to pass through that ordeal successfully, sends him out into the
world warranted by its seal fully qualified to carry out all the
more important duties of a properly regulated pharmacy, and to
safeguard the lives of the public by the correct dispensing to them
of the most deadly poisons when required. How much reliance
may safely be placed upon this Bloomsbury Square certificate let
a little of my experience relate : — Some years back I was in want
of a second assistant for our season, and as my then assistant,
though an excellent and most reliable man, thoroughly well up all
round, was unqualified, I asked for a qualified one. A newly turned-
out “ Pharmaceutical chemist ” replied, fresh from the Society’s
School, where he had distinguished himself by gaining either
medal or certificate in two or three different subjects. “ This is
the man for me,” thought I ; “ now I shall have confidence in my
staff.” Alas ! the first day he made three mistakes, showing actual
want of knowledge of drugs, doses, prescription reading, etc. , the
next some more or less trivial, some most serious, and so on from
day to day, until within a week I found that it was quite unsafe to
leave him in the shop alone. Fortunately for himself, he was a
most pleasant, gentlemanly young fellow, and candidly admitted
his incompetency and want of experience, and showed such a wish
to learn his business that on second thoughts I decided to attempt
to supply to him what the parent Society’s examiners had altogether
failed to notice the lack of — a proper knowledge of his business.
The time being a busy one, a great deal of the tuition
necessarily fell upon my unqualified (and twice rejected for the
Minor) assistant. What a spectacle ! A rejected Minor educating
a pharmaceutical chemist and School of Pharmacy prizeman.
But he and I succeeded, and when the season was over, I was able
to pass him on to a brother pharmacist with a good reference.
Sir, ought these things so to be ? I say no, and yet the Society
now thinks it has given qualification too cheaply, and wants
to make future pharmacists pay double for it. 0 tempora ! O
mores ! What a pharmacist wants to know is not so much
how many oxides of ethyl there are, as what he is to do when
a man is brought into his shop who has just taken a stiff dose of
prussic acid or some other deadly poison. The public expect to
find men behind a chemist’s counter who can give them sure and
ready help in such cases when they arise from time to time ; in
short, in my opinion the Minor examination is too scientific and
not sufficiently practical.
And this brings me to another point. Nowadays nearly every
railway porter, policeman, soldier, or sailor is more or less well up
in ambulance work, and many are the enthusiastic holders of a
“First Aid” diploma, whilst the generality of chemists and
assistants have only a more or less hazy idea of it, which they
have picked up by chance from time to time, and yet the public,
in case of accident, failing to find a doctor on the spot, make
straight for the nearest chemist’s shop. That this is the case in
other countries too the appointed system in Paris clearly recog¬
nises ; why then should not the Pharmaceutical Society add a
“First Aid” course to the curriculum for the Minor, and knock
Apbil 2i, 1897]
PHARMACEUTICAL JOURNAL.
365
out a great deal of the foolish scientific vapouring now so freely
indulged in, one of the results of which often is to make a man
feel altogether above the work behind the counter ? Mr.
McMillan’s idea of an “Assistants’ Qualification Examination”
may be a good one, but wants thinking out, and I trust, with
your usual ready help, a good discussion in your columns may
enable us to do this ; but I must and do protest against the
Society continuing to send out so-called qualified men with false
^colours flying at their mast-head.
Westgate-on-Sea, April 20, 1897. F. R. Bessant.
•Sir, — A letter — to me extraordinary— appears in your issue of
.April 17 from a correspondent in Glasgow, who complains that the
Minor examinations in Edinburgh are too difficult for his “reliable
young men ” assistants, and suggests that candidates should “ not
be confused with salts of tin and aluminum, which are only known
as chemical curiosities,” and that they should not be presented
with “ specimens of flowers never seen except in a conservatory.”
It may perhaps enlighten your mournful correspondent to know
(and my experience is not, I think, unique) that during the past
few years my reputation has hinged several times upon my ability
*o distinguish between these same occultly elusive and mysteriously
strange “salts of tin and aluminum,” and that the cordial
xelations of mutual esteem and confidence which exist between
every medical practitioner without exception in the neighbourhood
-and myself, are largely due to my ability (in common, it may sur¬
prise him to know, with others) to discourse learnedly regarding
“flowers and plants never seen except in a conservatory.” No
doubt such venerable specimens of the Pleisosaurus and Ichthyo¬
saurus of pharmacy, as your correspondent betrays a gushing fond¬
ness for, served a useful purpose in their time, but surely in this
nineteenth century such a desire to revert to a former condition is
gravely symptomatic of mental atavism, or, as these terrible exam¬
iners might say, retrograde metamorphosis.
311, Fulham Boad, 3. W. Wm. Luther Longstaff.
April 21, 1897.
Sir, — Permit me a word or two in regard to a letter by Mr. John
McMillan, Glasgow, in last week’s Journal. He writes to suggest
that an assistants’ qualification should be instituted. In leading
up to this, he deplores the large percentage of failures among the
young men who go up for examination from his establishments,
■and says that they mostly fail in two of the subjects. From his
remarks, he evidently means chemistry and botany, and he states
that “the failures were due to the examiners taking them (the
candidates) into regions quite unknown to them and entirely
beyond the scope of pharmacy.” He does not allege that they
went beyond the scope of the syllabus, and I have not the
slightest doubt that they did not ; if regions within its scope
were “quite unknown” to his young men, they were deservedly
-“ ploughed,” and that they were so is an indication that the ex¬
aminers know their work and recognise their duty to the public.
I am afraid that a thorough knowledge of chemistry and botany
can scarcely be expected if the requirements in these two subjects
be limited to the Pharmacopoeia. Perhaps Mr. McMillan would
support a suggestion that the Latin questions in the Preliminary
. -* ‘ should be entirely found within the boards ” of Pereira’s ‘ Selecta e
Prsescriptis ? If the Privy Council had been of the same opinion
as Mr. McMillan, they would not have sanctioned — it is said they
even suggested — the addition to the examining board of specialists
in chemistry and botany — men who probably never saw a Pharma¬
copoeia till their advent into pharmaceutic circles.
Mr. McMillan says he has no sympathy with the proposed
increase of the Minor fee to ten guineas, and he suggests a possible
strike of candidates for a year or two, to the financial embarrass¬
ment of the Society. There is not the slightest fear, sir, of a
-strike, and Mr. McMillan knows it, as I shall presently show.
Assistants are the men who profit by the increase in the fee. Since
the five-guinea fee for the Minor was instituted the value of an
assistant (qualified) has increased twenty pounds a year at least,
-and the value will go higher after the ten -guinea fee comes into
operation. A candidate can well afford to pay the fee, for he will
recoup himself for it and great part of his other expenses during
the first, year after he qualifies. Mr. McMillan suggests
that a modified Minor examination might be arranged
qualifying an assistant to handle and retail scheduled poisons under
■a qualified proprietor but not entitling him to start business or
.manage a branch. “Employers,” says Mr. McMillan, “willing
and anxious to carry out the provisions of the Pharmacy Act as it
is now interpreted, would find this qualification a great con¬
venience for obtaining reliable assistants, and to many assistants
it would prove a decided boon.” Now we have Mr. McMillan’s
recognition of the value of the Minor qualification. He can get as
many “ reliable assistants,” qualified, as he wants if he will pay
them the requisite salary. The men whose failure he deplores
would, presumably, be just as “reliable” and useful after they
had qualified as they were while unqualified. Where on earth,
then, would the “great convenience” of his proposed assistants’
qualification come in ? So far as I can see, it would certainly be a
“ great convenience for obtaining reliable (?) assistants” — on the
cheap. A decided boon to many assistants ! It would be the
worst thing that ever happened to them. It would simply keep
down their value, and I should be surprised to hear that any of
them, qualified or unqualified, would support such a proposal.
Mr. McMillan says he is not qualified to argue. Perhaps not. His
visual reach towards a bargain in assistants has, however, my
admiration.
April 19, 1897. Saltpetre (91/1).
Naval Dispenserships.
Sir, — On page 215 of the Journal a reference is made to dis¬
penserships in the Naval Medical Service being thrown open to
Irish licentiates, to the fact that they cannot yet be entered till a
new order in council has been effected, and that those appoint¬
ments are to be made by open competition, such competitions to be
conducted by the Civil Service Commissioners. With your
permission I should like to pass a few remarks about these
appointments. There are altogether fourteen of them ; a few
years ago there were sixteen, but as the duties at Ascension and
Yarmouth Hospitals were not sufficiently heavy to warrant an
expenditure of 5s. a day at each of these places, the order in
council was ignored and the appointments nominally turned over
to a surgeon. The order in council states that Major men only
are to obtain. the Is. a day charge of stores money when actually
in charge of stores ; this also has been set aside and the lower
qualified men levelled up to the higher trained men. Twenty-five
years of age is the limit for entry, but candidates with even the
Minor qualification are so scarce that it has been found
necessary on more than one occasion to extend the age to
27 years, in order to get a single candidate for a vacancy.
House accommodation to civil salaried officers in the Naval
Service should have a rental value of not less than one-sixth (-Jth)
of the official’s salary. This regulation extends at home to two
dispensers only. Dispensers are entitled to twenty-eight days’
leave of absence when their services can be spared, but owing to
the congested condition of the Navy and its increased numbers of
both ships and men, leave is not easily obtained, in fact it is more
frequently refused than granted.
One would imagine, judging by the open competition, that 5s.
a day, with a couple of rooms and board out, to an Irish pharma¬
cist was a large income. My advice to young men who are anxious
for permanent Government employment, and who are connected
with pharmacy in particular, is to employ a Civil Service coach
for a short period, then they will be more than likely able to get an
appointment in the Naval Medical Director General’s office as a clerk,
or as an assistant storekeeper in one of the Admiralty Departments, or
as a man clerkin thepublicservicegenerally. The commencing salary
is the same as a dispenser with the certainty of £350 a year long
before the dispenser attains his maximum of £182, in a great many
cases these appointments run up to £500 and £600 a year, vide Civil
Service Guide. As the Admiralty obtains the life blood of healthy
young pharmacists for ordinary assistants’ pay, one would naturally
think that the dispensing of poisonous medicines would be
relegated entirely to them, but such is not the case, for all
Royal Dockyard Surgeries at home and abroad, all Royal Marine
Infirmaries and the different sick quarters, as well as several naval
hospitals abroad, have their medicines, poisonous and otherwise,
nominally in the charge of surgeons, but dispensed in enormous
quantities by men possessing even a more meagre knowledge of
drugs than the Army medical compounders. It seems strange that
a Pharmacy Act should have been made for the protection of Her
Majesty’s civilian subjects. It may be, I hope not, that when a
man becomes a defender of our hearths and homes, his life and that
of his family are of less importance than the ordinary civilian.
Dispensers get neither honour nor glory. To illustrate this,
during the first Ashantee expedition a pharmacist, serving at
Haslar Hospital, answered the call for a volunteer to serve as
dispenser on board the hospital ship “Nebraski,” and at great
366
PHARMACEUTICAL JOURNAL.
[April 24, 1897
pecuniary loss went through as much danger as the officers of the
ship. They all had special promotion and decorations. He re¬
ceived nothing, not even the live shillings’ worth of silver stamped
with the Queen’s head and designated medal which was served out
to the humblest menial on board. As regards remuneration medicos
have it all also. A surgeon on joining the Navy gets 13s. 6d. a
day and is sent to Haslar Hospital for tuition for six months, with
no responsibility. His principal gets 60s. a day.
March 31, 1897. Videre est Credere (91/23).
ANSWERS TO QUERIES.
Special Notice. — Scientific, technical, legal and general information required
by readers of the ‘ Pharmaceutical Journal' will be furnished by the Editor as far
as practicable, but he cannot undertake to reply by post. All communications must be
addressed “ Editor, 17, Bloomsbury Square, London, W.C.," and must also be authen¬
ticated by the names and addresses of senders. Questions on different subjects should
be written on separate slips of paper, each oj which must bear the sender's initials or
pseudonym. Replies will, in all cases, be referred to such initials or pseudonyms,
and the registered number added in each instance should be quoted in any subsequent
communication on the same subject.
Cream Oil Liniment.— See reply to W. J. W. in Journal for
April 17, p. 346. [Reply to A. A. M.— 89/33.]
Messrs. Kay Brothers, Limited, Stockport. — Sample of sodium
chlorate received, and your request shall have attention.
Koch’s Tuberculin. — You will obtain this from Messrs. Zimmer-
mann, 9, St. Mary-at-Hill, E.C. [Reply to Correspondent. — 90/33.]
Mosses Identified. — 1. Brachythecium rutabulum and a smaller
species, AmUystegium serpens ; 2. Fissidens incurvus ; 3. Bryum
atro-purpureum. [ Reply to Pondo. — 89/41.]
Stenhouse, A. — Your communication, which was incorrectly
addressed to 17, Bloomsbury Square, W.C., has been forwarded
to the Publishers, 5, Serle Street, Lincoln’s Inn, W.C. (see notice
on p. 357).— 91/16.
Lure for Earwigs.— The page referred to should be 275 instead
of 335. The following are the details for preparing the earwig
bait : — Take foots sugar, or preferably rough honey, 2; beer, 1,
and boil together until all is dissolved, when cold add just a dash
of methylated spirit. [ Reply to F. S. — 90/29.]
Schulze’s Chlor-Zinc Iodine Solution.— The following
is the process given in Squire’s ‘ Methods and Formulae.’ Evapo¬
rate 100 fluid parts of liquor zinci chloridi, B.P., to 70 fluid
parts, dissolve in it 10 parts of potassium iodide, then add
one-fifth part of iodine. Shake at intervals until dissolved.
[Reply to H. W. W. — 90/43.]
Dispensing Query. — Yes, the prescription — Potass, iodid., gr.
40 ; tinct. quinine, §j. ; tinct. aurant., 3ij. ; aquae chloroformi, ad.
fviii. — represents a very frequent form of bad prescribing. The
writer of the prescription is evidently unaware that the alkaloid
is precipitated as iodide. You should certainly suspend it by means
of mucilage, and you might perhaps have an opportunity of calling
the prescriber’s attention to the incompatibility of the first two
ingredients. [Reply to Junior.- — 89/34.]
Mercury in Hair Wash. — Yes, you may certainly expect to
find that the continued use of a wash containing mercuric chloride
would ultimately cause darkening of “golden” hair. The sulphur,
which is a natural constituent of the hair, etc., or is excreted by
the skin, will eventually combine with the mercury salt ; if at the
same time the patient is taking sulphur in any form, the change
will be far more rapid and marked. Metallic salts are used in
many of the so-called hair dyes, which act through the formation
of dark sulphides in this way, but as the amount of sulphur
present in the hair is small the process is slow, so it is generally
added to the dye solution either as sulphur or as a thiosulphate.
[Reply to Norseman. — 89/17.]
C. W. G. Y. — The substance sent is ordinary sodium carbonate,
dried.
Associate.' — The oil consists chiefly of turpentine with some fab
oil partly emulsified with a caustic alkali.
Diploma. — According to the bye-laws, any person registered as a
pharmaceutical chemist under Section 10 of the Pharmacy Act,
1852, is entitled “ to possess and use a diploma stamped with the
seal of the Society.” [Reply to M. M. — 89/44.]
To Colour and Perfume Ointment. — Probably a little car¬
mine would be the best thing to tint the ointment with, add j ust-
enough to produce the requisite flesh tint. For perfume, oil of
neroli, with a very little bergamot, and a few drops of otto would
robably be most agreeable. Do not make the perfume too strong,
ut rather delicate. [Reply to G. H. H.- — 89/2.]
Marking the Government Stamp on Jugs. — Probably
nothing will hold permanently on to the sand-blasted government
stamp unless it is fixed on before firing, and then glazed over like
any other pattern. Your only way to get this done would be by
the makers at their works. After marking, the jugs would have to
be refired. All such varnishes as the recipe you send will wear off
in time. Probably a saturated alcoholic solution of magenta or of
methyl violet will bite into the roughened surface as well as any¬
thing, but will need to be renewed. The permanganate in
your formula is quite useless. Possibly by coating the aniline-
coloured stamp with a strong solution of potassium silicate you
might get a good result, but this can only be tried practically.
[Reply to Rhei. — 90/7.]
QUERY.
Wanted, formula for a composition used for filling brass or steel
tubes whilst they are bent to shape. It is apparently of resin and
gutta-percha or shellac. Used by cycle makers and scientific
instrument makers. — Spatula (91/13).
OBITUARY.
Earee. — On April 8, Thomas Earee, Pharmaceutical Chemist,
Staines, aged 77 years. Mr. Earee was a founder of the Society,
and his name has never once been omitted from the roll of mem¬
bers during the whole of the fifty- six years which have elapsed
since the Society’s inception.
Sarsfield. — On April 12, William Sarsfield, Pharmaceutical
Chemist, Durham. Aged 61. Mr. Sarsfield had been a member
of the Pharmaceutical Society since 1865, and was the local secre¬
tary for Durham. He took an active interest in the affairs of the
Durham Corporation, to which body he was elected in 1880. For
many years he acted in the capacity of an auditor of the Corpora¬
tion’s accounts and as a Justice of the Peace, frequently occupying
a seat on the Bench.
Cawdell. — On April 14, George Cawdell, Chemist and Drug¬
gist, Luton. Aged 71.
Armitage. — On April 19, Mary Hannah, wife of Nathaniel
Armitage, M.P.S., Chemist and Druggist, 114, Tong Road, Armley,
Leeds. Aged 49.
PUBLICATIONS RECEIVED.
Price-List of Fine Products issued by Burroughs, Wellcome
and Co. Pp. 53. London: Snow Hill Buildings, E.C. 1897.
From the Publishers.
Ozone ; its Commercial Production and Application. By E.
Andreoli. Reprinted from the Journal of the Society of Chemical
Industry, Feb. 27, 1897, pp. 15. London : Eyre and Spottis-
woode, 1897. From the Author.
COMMUNICATIONS, LETTERS, etc., have been received from
Messrs. Airey, Andrews, Armitage, Austen, Bayley, Bennett, Bessant, Bird,
Boa, Browne, Bullock, Burroughs, Cocks, Conner, Cooper, Cowley, Craeknell,
Crinon, Cruickshank, Davis, Duncalf, ' Edward, Elkington, Ennison, Evans,
Farr, Ferrall, Flatters, Forrester, Forshaw, Franklin, Gabell, Gadd, Gardner,
Gilligan, Greenish, Griffiths, Hicking, Hill, Horsfield, Hudson, Illingworth,
Ingham, Jenkins, Johnston, Kay, Kemp, Line, Longstaff, Lucas, Maben,
Macartney, Matz, Maunder, Moore, Parke, Pickard, Pollard, Poole, Richardson,
Shackleton, Stenhouse, Stokoe, Sturch, Taylor, Wallis, "Warren, Wellcome, Wol-
stenholme, Wood, Wright, Wyatt.
PHARMACEUTICAL JOURNAL.
367
THE MONTH.”
fin a German medical paper R. Koch gives an
/ccount of some further recent investigations
'' J* relating to tuberculin, from which he considers
important reshlts have been obtained. He attributes the
failure of' tuberculin as a remedy to the circumstance that although
it produced a reaction against the toxin generated by the
tubercle bacillus, and thus rendered the organism immune
in regard to that toxin, it did not produce immunity
against the bacillus itself. In his opinion, the glycerin
extract does not contain all the chemical constituents of the
bacillus, but only those which confer immunity against the toxin.
Hence he has endeavoured to obtain the substance capable of
producing immunity against the bacteria. On the basis of obser¬
vations on the influence of a preparation obtained by extracting
the bacilli with weak soda liquor and containing dead bacilli, he has
been led to try the effect of a mechanical disintegration, and by that
means has produced a preparation distinguished as TR, which he
believes will give immunity against the tubercle bacillus as well
as against the toxin it generates. This preparation is now being
produced at the Hochst colour works. Clinical trials in cases of
lupus are stated to have given very satisfactory results, and in
cases of tuberculosis treatment with the new preparation has had
the effect of stopping expectoration and improving the condition
of the lungs without causing any objectionable symptoms or detri¬
ment to the health, but these results are described with much
reserve, and it remains to be seen whether or not an important
advance has been made. — D. Med. Wochenschrift, 1897, No. 14.
The following modification of Power and
Determination Kleber’s process is recommended by Lyman F.
of Menthol in Kebler as being more expeditious : — To deter -
Peppermint Oil. mine combined menthol a weighed quantity of
the oil is boiled for one hour with about an
equal volume of normal alcoholic soda in a flask fitted with a reflux
condenser and titrated with normal sulphuric acid, using
phenolphthalein as an indicator. Each C.c. of alkali
consumed represents 0T56 gramme menthol in the state of
ester. To determine the total menthol a known quantity of
the oil mixed with an equal weight of acetic anhydride
and some sodium acetate is boiled for one hour under
a reflux condenser. After cooling, the mixture is washed with
water in a separator, and the aqueous layer drawn off, 50 C. c. of
water added with a few drops of phenolphthalein, and just enough
5 per cent, solution of soda to render the liquid pink after thorough
shaking. It is then well shaken with about 100 C.c. more water,
the watery liquid drawn off, and the oily layer again washed with
150 C.c. water. After separating the ace ty la ted oil is transferred
to a flask, boiled with normal alcoholic soda and then titrated.
Each C.c. of alkali then consumed represents 0T56 menthol, and
the quantity of free menthol is found by deducting from the
result so found the quantity previously determined in the state of
ester. A number of samples tested in this manner gave the
following results
Sp. gr.
Menthol.
at 15° C.
As Ester.
Free.
Total.
Commercial Menthol
_ _
—
99-66
99-66
Western . . . . . .
. 0-9112
3-72
29-02
32-48
Michigan .
. 9065
3-06
28-25
31-33
.
. 9147
4-51
29-92
34-43
New York .
. 9143
8-07
44-83
52-90
. 9099
7-31
45-43
52-74
Michigan .
. 9099
10-00
40-87
50-87
Unknown .
. S937
8-30
14-94
23-24
Michigan . .
. 9279
16-06
31-55
47-61
Mixture. . .
. 9079
4-68
38-30
42 -9S
Vol. LYIII. (Fourth
Series, Vol. IV.).
No.
1401.
As compared with normal Japanese oil generally containing
75 per cent, menthol, these results show that peppermint oil varies
considerably. But oil with a high percentage does not always
possess the desired fine aroma which is generally proportionate to
the amount of menthol esters, unless the presence of the
sulphur compound recently discovered by C. Kleber ( Pharm .
Review, 14, 269, and Schimmel’s Report, October, p. 48), or some
other disturbing condition interferes. Most of the oils were
probably genuine, except the one marked unknown, which was
mixed with turpentine as shown by its boiling point. On
examining peppermint oil the data to be determined are (1) speci¬
fic gravity ; (2) the boiling point, varying from a few degrees
below 200° C. to about 230° C., with some residue ; (3) the amounts
menthol, the total may vary from 30 to 80 per cent, and the com¬
bined menthol from 3 to 16 per cent. — Amer. Journ. Ph. , lxix., 189.
Professor E. Divers and T. Haga prepare
Hydroxylamine this compound economically by treating a
Sulphate. concentrated solution of commercial sodium
nitrite (2 mols. ) and of sodium carbonate
(1 mol.) with sulphur dioxide till just acid, whilst it is kept well
agitated at two to three degrees below zero in a mixture of ice and
brine. At this temperature the conversion of the nitrite into
oximido-sulphonate is apparently perfect and, on gently warming
with a few drops of sulphuric acid, the oximido-sulphonate rapidly
hydrolyses into oxyamido-sulphonate and acid sulphate. The
solution is then kept at 90° to 95° for two days, by the end of
which time all oxyamido-sulphonate will have hydrolysed into
hydroxylamine sulphate and sodium acid sulphate, whilst the
quantity of ammonium salt produced will be so small as only to be
capable of detection by chloroplatinic acid in the last mother-
liquors of crystallisation. The crude hydroxylamine equals about
nine-tenths of the sodium nitrite taken, and as re-crystallisation of
the sodium sulphate yields one-tenth more of hydroxylamine sul¬
phate, the nitrite will yield, on the small scale, nearly its own
weight of pure hydroxylamine sulphate. — Journ. Coll. Science
(Japan), through Chem. News, lxxv., 181.
The use of sodium peroxide as a third group
Sodium reagent is advocated by S. W. Parr, who has
Peroxide found it possible, by this means, to avoid
US a Group several of the complications usually attending
Reagent. the ordinary procedure for the separation of
the metals of the iron group. His method of
procedure is to add a small porcelain teaspoonful of the peroxide
to the slightly acid solution, which is then heated to complete
decomposition, and finally boiled for some minutes after all the
oxygen seems to be driven off. Iron, manganese, cobalt, and nickel
are precipitated, whilst aluminum, zinc, and chromium remain in
solution. A table based upon the application of this method to
qualitative analysis accompanies the paper. — Journ. Am. Chem.
Soc., xix , 341.
H. Moissan finds that on heating pure iron
Iron and the carbon of sugar in the electric furnace,
Carbide. and then allowing the mixture to cool slowly,
the metal contains merely a slight trace of
combined carbon, and forms a grey casting, which solidifies towards
1150°. If, however, the metal is run into a mould at a temperature
of 1300° to 1400°, it contains a larger quantity of combined carbon
on cooling and also graphite, forming white cast metal. Finally,
iron saturated with carbon at 3000° and cooled abruptly in water,
shows signs of abundant crystallisation, and contains a definite
crystalline carbide, Fe3C, which is identical with that of steel.
The formation of this carbide has been observed in the liquid
metal only. It is noteworthy that though this was one of the first
368
PHARMACEUTICAL JOURNAL.
[May 1, 1897
metallic carbides known, it is the latest to be prepared in quantity
by direct synthesis. Water does not affect it, even at 150°, but on
treatment with hydrochloric acid, a mixture of hydrogen and
methane is evolved. — Comptes rendus, cxxiv., 716.
Dr. Smirnow has produced a diphtheria anti-
Eleet roly tic toxin of great efficacy by electrolysing virulent
Diphtheria diphtheria broth cultures, the saving in time
Antitoxin. and expense over the ordinary method being very
great. The new preparation is claimed to en¬
tirely protect animals from the effects of diphtheria poison, even
when employed in smaller quantities than the oi’dinary therapeutic
serum, whilst in itself the artificial antitoxin is said to be quite
harmless.- — Arch, des Sciences Biol. , and Nature, lv., 597.
Lainer advocates the following tests, which
Benzol are easily applicable, to distinguish between
and benzol and benzine : — Coal tar benzol is coloured
Benzine. carmine red on addition of a crystal of iodine,
while petroleum benzine is coloured violet. This
test is very reliable, and is even applicable in admixtures of the two.
To 2 C.c. of the benzol or benzine add 3 to 4 drops of a clear, ethereal
solution of sandarac (1 : 10). A permanent turbidity is imparted to
benzine, while benzol, which is turbid at first, soon clears. More
sandarac solution being added causes the latter to become turbid.
On shaking benzol with traces of alcohol it becomes turbid, while
benzine remains clear. — Pharm. Era, xvii., 329.
Antony and Lucchesi state that when a smaller
Purple Of quantity of mercurous chloride than is required
CaSSlUS. is added to a solution of auric chloride, metallic
gold is deposited, according to the equation
3HgCl + AuCl3 = 3HgCl2 + Au, but upon adding excess of
mercurous chloride, that which remains unchanged assumes the
characteristic colour of purple of Cassius ; similar results are
obtained with cuprous chloride. It would thus appear that the true
purple of Cassius is merely stannic acid mechanically coloured
with metallic gold. — Journ. Ghem. Soc., lxxii. , 43, after Gazzetta.
This compound of phosphorus and guaiacol
Guaiaeol is prepared by Ballard as follows : 124 grammes
Phosphite. of crystallised guaiacol is treated with 50
grammes of caustic soda dissolved in 90 per
cent, alcohol ; to the clear solution phosphorous trichloride is run
in through a tapped funnel until the solution is no longer alkaline
to phenolphthalein ; the precipitated salts are filtered out, the
alcohol is distilled off, and the residue extracted with absolute
alcohol, which only dissolves the phosphite of guaiacol. The solu¬
tion is then evaporated on the water bath and the salt crystallised
out, purified by recrystallisation from absolute alcohol, and
finally dried over sulphuric acid. The crystals have the formula,
P‘(C6H4:0CH3‘0), and therefore represent the neutral phosphite of
guaiacol. It forms a white crystalline powder, melting at 77° -5.
Creosote treated in a similar manner gives a thick reddish-yellow
liquid which consists of the phosphorous esters of the various
phenols present in the creosote ; to this the author proposes to
give the name “phosphatol.” — Repertoire de Pharm. [3], ix., 104.
This preparation, which has met with some
Holoeaine. success as a substitute for cocaine, is
yi-diethoxyethenyl -diphenyl-ami dine. It is ob¬
tained by the union of molecular quantities of phenacetin and
p-phenetidin with the separation of water. Holoeaine is a crystal¬
line base, insoluble in water, melting at 121° and forming
crystalline salts, which are difficult to dissolve. The hydrochloride
crystallises in white needles, which dissolve readily in boiling
water. The cold saturated solution, however, only contains about
2-5 per cent, of the salt. The aqueous solution is slightly bitter in
taste, is perfectly neutral, and is not decomposed by boiling. The
solutions of the holoeaine hydrochloride have been found to keep
very well, a 1 per cent, solution allowed to stand in an open vessel
for two months did not show the slightest cloudiness. — Pharm.
Centralh., xxxviii., 163.
This is a recently introduced preparation
Metsethyl. for use as a local ansesthetic. It is a
clear colourless neutral fluid, the odour of
which reminds one somewhat of chloroform. The taste is
burning and bitter, it is soluble in any proportion in alcohol,
ether, and chloroform. It burns with green-edged flame, leaving
no residue. It consists for the greater part of ethyl chloride
and small quantities of methyl chloride and chloroform. The
boiling point of the solution was found to be 10'5° C., the specific
gravity is 0'9173 at 4° C. It is decomposed by alkalies into
alcohol, hydrochloric and formic acids.— Pharm. Zeitg., xlii., 200.
Wolpert has been measuring the amount
Carbon of C02in the air enclosed in articles of clothing.
Dioxide in The samples were taken through a Pravaz
Clothes. syringe and the C02 was measured by de¬
colorising standard alkaline phenolphthalein
solutions, mainly by the air under experiment and finally by a
measured quantity of standard weak acid solution. The persons
upon whom the experiments were tried wore their ordinary clothes.
In a room having 0-321 per thousand C02 the clothes measured at
the breast had 0-561 per thousand C02 at 13 ’4° 0., and 53 percent,
relative humidity. Upon slow walking this dropped to 0'495 per
thousand, fast walking increased till reaching 0'748 per thousand
for hard work. Perspiration did not always affect the rate of in¬
crease, which seemed to depend more upon the texture of the
clothes and the extent to which they were affected by the ventila¬
tion due to rapid movement. In the open air the extent seemed
to vary with the velocity of the wind. With headgear an increase
of 0 '3 per thousand of C02 gave marked discomfort. By far the
least increment of C02 was shown by a straw hat. Considerable
increase above that contained in the air occurred in footgear, but
very little in drawers. The C02 in feather-beds increased as much
as 35 per cent, over that contained in the air of the room. The
importance of well airing bedclothes every day is strikingly
indicated by this result. — Journ. State Med., v., 131.
When phosphoretted hydrogen is passed into
New phosphoryl chloride containing a little hydro-
PhOSphOPUS bromic acid, heated to 50° on the water bath,
Oxide. or if the phosphoryl chloride is replaced
by certain bromo-derivatives of that body, or,
again, if PH4Br be heated to 50° in a sealed tube with POCl3, a
reddish-yellow solid body is formed which, according to Besson, is
a new oxide of phosphorus, P20. It is again heated in a sealed
tube with more POCl3 ; after filtration in vacuo, it is extracted
with boiling CS2 to remove adherent POCl3, then washed
with boiling water and dried in vacuo, at first over sulphuric
acid in the cold and finally at 100°. So purified it is a
very light pulverulent body, reddish-yellow in colour, stable
in vacuo at 100°, but towards 135° it loses a notable portion
of its oxygen. It burns when lighted in air, and reacts with
concentrated nitric acid like phosphorus itself. It might be re¬
garded as the anhydride of hypophosphorous acid ; although, when
heated to 100° in a sealed tube with water for twenty-four houi’s,
no formation of hypophosphorous acid takes place, only a trace of
phosphorous acid derived from the oxygen of the air contained in
the tube is found. If the temperature be raised to 130°-140°, there
is still a little phosphorous acid formed even in a vacuous tube,
but the atmosphere of the tube contains phosphoretted hydrogen ;
May 1, 1897]
PHARMACEUTICAL JOURNAL.
369
this would indicate that the body is not phosphorous anhydride,
its position in this respect appears to be analogous to that of nitrous
oxide. — Comptes rendus, cxxiv., 763.
According to Fritzsche, argentol is a com-
Argentol. pound of silver with oxychinolin obtained from
chinosol. It is more suitable for use than lac¬
tate or citrate of silver. It is readily decomposed, and in the
presence of septic substances splits up into oxychinolin, which is an
active antiseptic, and metallic silver, both of which have bacteri¬
cidal action. Argentol is so readily decomposed that if boiled
with water it at once deposits minutely divided silver. It is a non¬
irritant, non-poisonous powder, difficult to dissolve, but can be
easily distributed. It is an excellent substitute for iodoform, and
other silver preparations which on decomposition give silver
oxide instead of metallic silver. It is applied as a powder to
wounds, granulations, festerings, skin diseases, ulcers, also as an
ointment with vaseline and lanolin, 1:50- 100, and in emulsions or
injections for gonorrhoea, 1:300 — 1000.— Ph. Centralh., xxxviii., 163.
Darmstaedter and Lifschiitz find in woolfat
Chemistry of Myristic acid melting at 53°-54°, Carnaubic
Woolfat. add 'melting at 72°-73°, a new dioxyacid to
which the name Lanoceric add is given ; this
melts at 103-104 and has the formula C30H6O4. It loses a molecule
of water at the melting point, but takes it up again on
recrystallising from alcohol. With mineral acids it again loses a
molecule of water, and the resulting body, which is not an acid
hut a lactone, melts at 86°. Alcoholic solutions of mineral acids
give another neutral body, melting at 97°, which has not been
fully examined. Another new oxyacid melting at 87-88°, for which
the name Lanopalmitic add, C1GH3203 is given. It forms an emulsion
when melted with water. A new alcohol, for which the authors
propose to name Carnaubyl alcohol, as well as ceryl alcohol, and an
unsaturated alcoholic body which was not isolated, are also present,
together with cholesterin. — Pharm. Zeitung, xlii., 123.
The leaves of Palicourea rigida, a native of
Chemistry Brazil, are stated to have a diuretic and dia-
Of phoretic action. They are employed in Brazil
Douradinha. for the treatment of dropsy and syphilitic skin
diseases in the form of an infusion of either the
fresh or dried leaves. Among the natives the dried leaves are
stated not to be poisonous, while the fresh plant shares with other
species of Palicourea the name of rat poison. It was found by
Peckholt, who examined the plant in 1866, that no volatile alkaloid
was present. The drug contained, however, a non-volatile base
and three organic acids. One of these acids, consisting of a yellow
oily liquid with an overpowering odour, was found to be intensely
poisonous, one drop injected into a pigeon being enough to cause
death. This was called myotonic acid. A crystalline palicouric
acid, an amorphous tannin, and another amorphous non-toxic
bitter principle were isolated by this worker. Santesson has
repeated the examination of the drug and has confirmed the pre¬
sence of an alkaloid. The quantity of material was, however,
insufficient for him to determine if this was identical with the base
of Peckholt ; after the removal of the alkaloid the extract still
remained strongly toxic. — Archiv der Pharm., 235, 143.
Dietze makes an interesting communica-
Maturin tion on this balsam, showing that it is rarely
Copaiba found to correspond to the requirements of
Balsam. the German Pharmacopoeia. The balsam
is somewhat drill, and deposits, after standing, a few drops
of water and some suspended matter. It is a viscid
liquid, of the specific gravity of 0 ‘9849. After filtration in the
steam funnel it showed a specific gravity of 0'9832. The filtrate
is of a golden-yellow colour, with an agreeable aromatic odour,
and is without any fluorescence. Mixed with ether, pure alcohol,
amyl alcohol, benzol, chloroform, or fatty oils, it remains clear,
in 90 per cent, alcohol the mixture is a little clouded, heated to
130° it does not gelatinise. The balsam contains 59 '28 per cent, of
resin, and 40 '72 per cent, of volatile matter ; it stands the carbon
bisulphide and ammonia tests, and showed the following charac¬
teristic figures : —
Maturin Balsam.
Maracaibo Balsam.
a
b
Acid number .
78-17
84-0
82-54
Ester ,, ..........
4'26
6-2
5-77
Total acid number .
82-43
90*2
88-31
— Pharm. Zeitg., xlii., 241.
A severe case of copaiba rash following the
Copaiba daily use of three ten-minim capsules of copaiba
Poisoning. oil is reported by Dr. Thompson. The appear¬
ance of the eruption was similar to that of
measles, the whole face and neck being covered with a bright red
elevated rash ; the chest, abdomen, and lower extremities were
also covered. Great itching accompanied the rash. On discon¬
tinuing the capsules the patient gradually improved, although
traces of the eruption remained on the anterior aspect of the thighs
for seven days. — B. M. J., 2,97/522.
A sample of guaiacum examined by Doebner
Guaiaeum and Liicker contained guaiaretic acid, 11 ‘15 per
Resin. cent. ; guaiaconic acid, 50 '0 per cent. ; guaiacic
acid (ft resin), 1 1 *75 per cent., all soluble in
alcohol, and matter insoluble in alcohol containing 9 '64 per cent,
of mucilage, 24 '96 per cant. Guaiaretic acid forms white lustrous
laminae, which melt at 86° ; the benzoyl derivative forms nearly
colourless crystals melting at 131°. The authors find the composi¬
tion to be C20II.21O4. Guaiaconic is a white amorphous powder
melting at 81-83°. Guaiacic acid was not obtained pure ; the ben¬
zoyl derivative is a white crystalline powder which melts at
155-158°. “Guaiacum oil ” is prepared by boiling guaiacum resin
with sodium carbonate solution, filtering, saturating the solution
with C02, again filtering and extracting with ether ; the oil is left
when the ether evaporates. By acidifying the alkaline solution
after it has been extracted by ether, guaiacum yellow is precipi¬
tated, which may be crystallised in yellow octahedra. This has
the composition C20H20O7, and melts at 115°, dissolving in sul¬
phuric acid with a bright blue colour. — Journ. Chem. Soc., lxxii.,
1, 165, after Archiv der Pharm.
Since many flowers do not contain the whole
Extracting1 the of their odoriferous principles ready-formed, but
Perfume secrete them gradually as long as the vital
of Flowers, action continues, Passy suggests that by pro¬
longing the life of the blooms for a further
period than is possible by the process of enfleurage with fats, as at
present carried out, a better yield and more satisfactory results
would be obtained. For this he suggests the use of water.’ The
flowers are immersed in that fluid, and as soon as it becomes
saturated with the odour it is replaced with, fresh. The aqueous
solutions are then extracted with ether, upon the evaporation of
which the odorous bodies are left in a pure state. Simple water
might with advantage be supplemented by a saline solution of the
same osmotic power as the juices of the plant. The author states
that he has experimented with a number of flowers, with good
results, particularly in the case of lily of the valley. — Comptes
rendus, cxxiv., 783.
370
PHARMACEUTICAL JOURNAL.
[May 1, 1897
Tschirch and Hildebrand have examined the
Aearoid red resin of Xanthorrhcea australis, and the
Resins. yellow resin of X. hastile. They find that the
latter contains 4 per cent, of free para-cnmaric
acid, with a little cinnamic acid ; also the same acids combined as
tannol esters, and a doubtful trace of vannilin ; the bulk of the
resin consists of xanohoresinol tannol, C43H45O10, in the form of an
ester with the para-cumaric acid. The resin of Xanthorrhaia
australis differs slightly from the above, first in containing no
cinnamic acid, either free ot combined, and secondly in the com¬
position of the tannol, erythroresinoltannol, C40H4llO10. It would
seem, therefore, that xanthoresinoltannol and erythroresinotannol
are homologues. — Schweiz. Woch. fur Chem. und Pharm., xxxv.,
121, 138.
The examination of this plant by H. Y. Arny
Parthenium throws some doubt on the existence of the
HysterophOPUS. alkaloid described by Dr. Jose R. Tovar under
the name of parthenine (Ph. J. [3], xv., 987).
About 1 per cent, of a crystalline product was obtained which was
neither an alkaloid nor a glucoside, but appeared to be more
analogous to santonin. — Amer. Journ. Pharm., lxix., 169.
M. P. van Tieghem continues his very
Ovules remarkable observations on those families of
Without a Phanerogams which are characterised by very
Nueellus. rudimentary ovules. In addition to the ten
orders (the Nuytsiacese, Elytranthacese, Den-
drophthoracere, Treubellacese, Loranthacese, Arceuthobiacese, Helo-
sace®, Ginalloaceae, Viscacese, and Balanophoracese) which make
up the Inovulie or Loranthineas, distinguished by the entire absence
of a true ovule, there is another group, the Innucellag or San-
talinea:, which occupy a borderland between them and those
endowed with perfect ovules. In these the ovule is reduced, not
to a nueellus, as has been erroneously stated, but to a funicle, or
ovular leaf not differentiated into petiole and lamina, the nueellus
and the integument being both entirely suppressed. In this group
are included also ten orders, viz., the Santalacete, Arionacese,
Schcepfiacere, Myzodendracese, Sarcophytacese, Opiliace;e, Antho-
bolaceje, Olacaceee, Aptandraceaj, and Harmandiacece. In these
orders the mother- cell of the endosperm and of the oosphere
erroneously called the embryo-sac, originates directly beneath the
epiderm in the cortex of the foliar leaf, the cortex not being
elevated above the surface so as to form the emergence known as
the nueellus. In this group are comprised about fifty genera.
The Olacaceas, Aptandracese, and Harmandiacece form the division
Olacales, characterised by the presence of a corolla ; the remaining
seven orders, which are apetalous, constituting the Santalales. —
Bull. Soc. Bot. de France, vol. xliii., p. 543.
From observations on the stigma of Martynia,
Mechanism Mimulus, Bignonia, and Tacoma, the stamens of
Of Portulaca grandiflora, of the Cactacece (espe-
Sensitiveness. cially Opuntia amyclea) and Berberideae, and the
leaves of Mimosa, Professor A. Borzi derives
the following conclusions as to the mechanism of the motile pheno¬
mena resulting from a blow or from a sharp concussion. The cause
lies in special protoplasmic elements, differentiated physiologically
as instruments for the reception and transmission of irritation.
They consist of very delicate threads, composed of cells arranged
in longitudinal rows in the direction followed by the irritation.
The cells have a very thin membrane, which is very contractile,
and is endowed with strong osmotic properties. Minute perfora¬
tions, through which very fine protoplasmic filaments may pass,
frequently traverse their walls. The action of stimuli which
induce variations in the state of imbibition of the protoplasm, is
followed by a rapid change in the turgor and tension of the cells,
thus altering the position of the irritated organ. For the purpose
of retaining temporarily the water expelled from the protoplasm
during this process, every sensitive plexus is traversed by inter¬
cellular spaces forming a connected system, which varies in its
special character in different cases. In some cases the median
layer of the membrane of the sensitive cells becomes transformed
into a semi-fluid substance, which constitutes a receptacle for
water. The gelatinisation of this layer sometimes fills up the
spaces with an absorbent colloidal substance. The rapidity with
which the sensitive plexi respond to the action of stimuli depends
on the presence or absence of this substance, or on the degree of
its consistency. The water which fills the intercellular spaces
contains various organic substances in solution, mostly of the
nature of glucose. Sometimes they are filled with air or seme
other gas.- — II Naturalista Siciliano, 1897, p. 168.
Herr G. Kraus {Flora, 1897, p. 54) has
Function of made a series of observations, chiefly on the
Calcium rhizome of Bumex obtusifolius grown in
Oxalate. different soils, from which he concludes that
calcium oxalate is by no means invariably
merely an excretory product in the life of plants ; but that it
performs the function of supplying the necessary amount of lime
to the aerial organs. Similar results were obtained as to the
function of this salt in the bark of various trees and shrubs. With
the CactaceEe the results were mainly negative, but not con¬
clusively so.
According to Herr T. Kosutany ( Landwirth -
Formation sch. Versuchs-Stationen, vol. xlviii., p. 13), leaves
Of contain a somewhat larger amount of nitrogen
Prottids. by night than by day, there is a larger propor¬
tion of ammoniacal salts, and the amount of
proteids is not reduced. On the other hand, the amount of nitrates
is larger in the daytime. From these facts it would appear prob¬
able that the nitrogen of the nitrates is converted into proteids
more by night than by day. No asparagin could be detected in
the night, this substance being probably converted into proteids.
Th<j nett result obtained is that the raw materials for the produc¬
tion of proteids are absorbed by the plant chiefly in the daytime,
but that the final processes take place chiefly by night.
Herr Marschall (Archiv J:ir Hygiene, vol.
Myeele Of xxviii., p. 1 6) has investigated the composition
Mould-Fungi, of the myeele of several typical mould-fungi,
Aspergillus niger, Penicillium glaucum, and
Hucor stolonifer, and reports that the average percentage of
proteid substances is as high as 38, while that of cellulose is only
5 ‘03, and of substances soluble in alcohol, 14-03. In the com¬
position of their myeele mould-fungi occupy an intermediate
position between bacteria and the higher plants, containing more
nitrogenous matter and less carbohydrates than the latter, more
carbohydrates and less nitrogenous matter than the former . As con¬
trasted with the spores, the myeele of Penicillium glaucum contains a
larger amount of proteids, but not nearly so much cellulose, starch
or substances soluble in alcohol.
According to Dr. T. Bokorny, the simpler
Organic Nourish- the composition of organic substances, the
ment Of Green more readily are they assimilated by green
Plants. plants. Thus C02 is readily converted into
C6H1Sj06, while plants are unable to produce
a carbohydrate from glycerin C3H803. As a general rule, com¬
pounds with one atom of carbon are readily assimilable, the
difficulty increasing with the increase in the atoms of C. Sub¬
stances which are composed of C and H only are not so favourable as
May 1, 1897] ’
PHARMACEUTICAL JOURNAL.
371
those which consist of C and 0 only, or of C, H and 0. Pepton is a
peculiarity excellent food-material for fungi, and probably also for
algae. — Biol. Centralblatt, 1897, p. 1, et seq.
M. P. van Tieghem points out that the tuft
Hairs which of hairs which spring from the sepals behind
are not the stamens in the Santalaceae are not trichomic,
Trichomes. but are of endogenous origin, originating
from cells of the exoderm. This is well
seen in Thesium humifusum, and occurs also in other cases. — MoroVs
Journal de Botanique, 1897, p. 41.
J. B. Davy refers to the fact that the manu-
Vegetable facturers of “Yucca-root soap” claim to use in
Soaps. its preparation the roots of Yucca filamentosa,
imported from Mexico, and suggests that
indigenous Indian soap root ( Chlorogalum pomeridianum ) might
take the place of the imported article. The Indian soap root
abounds on the hills around San Francisco Bay, and is used for
laundry work by economically minded Mexican and Irish families,
whilst in some parts of California, especially towards the south,
the root of Ghenopodium californicum is used for washing purposes.
— Erythea, v., 40.
F. S. Hyde finds that if a clear, filtered
Modified solution of calcium hypochlorite (bleaching
Thallecquin powder) be substituted for the bromine or
Test. chlorine water in the thalleoquin test for
quinine, the results are more satisfactory so far
as certainty and brilliancy of the test are concerned. After acidula-
tion with one drop of sulphuric acid (1:4) the hypochlorite solution
is added through a small filter to the quinine solution in a test-
tube until the blue fluorescence just disappears and the solution
acquires a faint golden tint ; then add a few drops of dilute
ammonia (1 : 3), when a clear emerald green colour should appear.
The tint thus produced is said to appear more brilliant than that
obtained through the agency of bromine water. On the addition
of a slight excess of dilute sulphuric acid to the green solution a
blood-red tint will be produced, which may be considered comfirma-
tory, but this is not always the case when bromine water has been
used in the preliminary operation. — Journ. Am. Chem. Soc.,
xix., 331.
Some experiments with these rays, by
Kathode A. A. C. Swinton, formed the subject of a paper
and recently read before the Royal Society, and it
X Rays. is interesting to find that X rays can only be
produced by kathode rays when these strike
solid matter, which must doubtless be positively electrified. The
tube specially constructed to determine this point contained two
aluminum kathodes, and it was thought that the opposing streams
of kathode rays might possibly produce X rays at the point where
they met. But though the exhaustion of the tube was so high
that the alternative spark in air leapt fully eight inches, and
X rays were given off in considerable quantity, they appeared to
come entirely from portions of the glass of the tube that were
covered with green fluorescence.
At a recent meeting of the Physical Society,
Niekel T. A. Garrett and W. Lucas communicated the
in results of some experiments upon telephones
Telephones with nickel magnets. A magnetised nickel
rod is wound with insulated wire and then
fixed vertically by a clamp at its lower end, whilst a pinewood dia¬
phragm is rigidly attached to the top of the rod in a horizontal
plane. The rod just passes through the middle of the diaphragm,
which is entirely supported by it, and fixed with sealing-wax. The
instrument dce3 not work well as a “receiver,” an ordinary
telephone being preferable for that purpose. The nickel “ stress ”
telephone, however, gave better articulation than an ordinary
“watch” telephone, though the sounds were feebler, and the
articulation was clearer with three cells than with six.
A new primary battery is described in the
Hot Fluid Scientific American, which is a modification of
Primary the Daniell battery, in which the zinc and
Battery. copper have a large superficial area, and the
action of the copper sulphate solution is greatly
accelerated by the application of heat. The cells are rectangular
and measure If in. by 8 in. by 11 in. high. Each contains two
wide plates of zinc and one of copper, strips of wood being used
to prevent contact and bolts passing through to connect the zinc
plates. A rectangular copper feeding tube, an inch square and
closed by a perforated diaphragm, is placed at one end of the cell,
where it rests upon a projection of the copper plate, about half¬
way down. The copper sulphate solution is fed through this
tube, or crystals of the salt may be packed in it. Several of the
cells are fixed in a bottomless external vessel, and small oil stoves
are placed beneath to heat the cells, which are claimed to yield
very high results.
Those who have studied rocks from the point
Magnetic of view of their magnetic properties, observes a
Rocks. writes in Nature, have long been aware of the
existence of certain isolated portions, or zones,
endowed with intense magnetisation, the distribution of which, in
general, bears no fixed relation to the direction of the earth’s mag¬
netic field. The theory has been frequently advanced that these
singular points owe their magnetisation to discharges of lightning,
and this theory is said to have received a remarkable confirmation
at the hands of Dr. G. Folgheraiter, who finds, as the result of
numerous observations of the remains of walls and ancient build¬
ings in the Roman Gampagna, that these structures frequently
exhibit singular points and zones in every respect identical with
those observed in rocks. It is suggested that the presence of
singular points in walls might be accounted for by supposing that
they had existed in the stone before it was used for building ; but
this explanation is incapable of accounting for the singular zones
in which a number of adjacent stones, as well as the mortar con¬
necting them, were found to be so powerfully magnetised, that
even a small detached portion of the mortar was capable of deflect¬
ing a compass-needle through 180°. These zones could only have
derived their magnetisation after the wall had been built, and the
presence, in some cases, of cracks down the wall in the neighbour¬
hood of the singularities, such as would be caused by lightning,
tends to confirm the present theory of their origin.
That faith with regard to the age and
Cobwebs respectability of wine may be implicitly reposed
and in cobwebs and dust encrusting the bottles
W ine. containing it has long ceased to be believed by
connoisseurs, but Nature has just discovered
that trust in this direction may be misplaced. The source of
information relied upon by our leading scientific journal is a
Bulletin (No. 7) of the Division of Entomology of the U.S. Depart¬
ment of Agriculture, according to which an industry has recently
sprung up in France and Pennsylvania, which consists of the
farming of spiders for the purpose of stocking wine cellars, and thus
securing an almost immediate coating of cobwebs to new wine
b >ttles, giving them the appearance of great age. This industry
is carried on in a little French village in the Department of Loire,
and near Philadelphia, where Epeira vulgaris and Nephila plumipes
are raised in large quantities and sold to wine merchants at the
rate of ten dollars per hundred.
372
PHARMACEUTICAL JOURNAL.
[May 1, 1897
PHARMACEUTICAL SOCIETY
MEETING OF THE COUNCIL.
WEDNESDA Y, APRIL 28, 1897.
Present :
Mb. Walter Hills, President.
Mr. John Harrison, Yice-President.
Messrs. Allen, Atkins, Bottle, Carteighe, Hampson, Martindale,
and Savory.
The President said this was a meeting specially summoned for
the purpose of reading the second time and confirming the amended
byedaws, which were read a first time at the last meeting of the
Council. He did not propose to make any remarks on the present
occasion, but would simply move —
“ That the proposed new bye-laws which were read the first time at the
meeting of the Council on April 7, 1897, and which were published in the
Pharmaceutical Journal of April 10 (Pp. 315, 316) be now read a second time
and confirmed."
The Vice-President seconded the motion, which was at once
carried unanimously.
Mr. Bottle moved that the new bye-laws be taken as read, which
was seconded by Mr. Martindale, and agreed to.
This terminated the proceedings.
DONATIONS TO THE LIBRARY AND MUSEUM.
At a meeting of the Library, Museum, School and House Com¬
mittee, held on Wednesday, the 28th inst. , the Librarian presented
the following report of donations
To the Library (London)*
Kaiserliche Leopoldinisch-Carolinische Deutsche Akademie der Naturforscher: —
Nova Acta, Bd. 65, 66, 67 ; Katalog der Bibliothek, Lief. 7.
Dr. Louis Planchon, Montpellier : — Observations et experiences sur l’ouverture
des fleurs de 1’CEnothera lamarckiana, 1896.
Professor Dr. A. Meyer, Marburg : — Viola tricolor in morphologischer, anato
mischer und biologischer Beziehung, von H. Kraemer, 1897.
College of Preceptors, London : — Calendar, 1897.
Mr. W. Moore, Dibrugarh, Assam : — The works of Virgil, with notes by Bryce.
Smithsonian Institution, Washington : — Annual report, 1894.
Dr. Karl Dieterich, Helfenberg : — Helfenberger Annalen, 1896.
Mr. H. N. Bidley, Singapore : — Annual report on the Botanic Gardens, Straits
Settlements, 1896.
Dr. Paul, London : — HuLtihme Congrks Internationale d’Hygifene et de Demo¬
graphic, 1894, Comptes-rendus et M5moires, tomes 2-8.
To the Library (Edinburgh).
Pharmacy Board of Victoria : — Pharmaceutical Register for 1896.
American Pharmaceutical Association : — Proceedings, 1896.
Mr. A. Noble, Edinburgh Pharmaceutical Journal, vols. 22-25, 1891-95.
Messrs. E. B. Squibb and Sons, Brooklyn : — Ephemeris, vol. 4, no. 5.
The following donations were reported by the Curator : —
To the Museum (London).
Mr. T. Wardleworth, Liverpool : — Fruits of Pilocarpus microphyllus.
Mr. D. O. Evans, Ashburton : — Specimen of Burnt Hartshorn.
Messrs. Potter and Clarke, London : — Living plant of Anhalonium lewini.
Mr. E. N. Butt, London : — Specimen of Chicle, used in the preparation of
chewing gum.
Mr. C. Hanbury, London : — Specimen of the Oil of Australian Sandalwoo'd,
prepared by the late Mr. D. Hanbury, and a specimen of Balm of Gilead, which
originally belonged to one of the Godfreys, of Southampton Street, Strand.
Mr. J. J ohnston, Aberdeen : — Specimen of Scotch Camomiles.
Mr. E. D. Gravill, Hull : — Specimen of Hybrid Orange.
Messrs. Parke, Davis and Co., Detroit, United States, America. — Living
specimens of and dried tops of Anhalonium lewini and A. williamsi, and flowers
of Cereus grandiflorus, preserved wet.
Dr. Kerr Cross, Uganda : — Specimens of poisoned arrows and of plants used in
medicine by the natives.
Messrs. Kay Brothers, Stockport A fine specimen of crystals of sodium
chlorate presented by the manufacturers, Messrs. Bowman, Thompson and Co.,
Nortwich.
NORTH BRITISH BRANCH.
MEETING OF THE EXECUTIVE.
A meeting of the Executive of the North British Branch was
held in the Society’s House, 36, York Place, Edinburgh, on Friday,
April 23, at 11 a.m., Mr. J. Laidlaw Ewing in the chair. Present :
Messrs. Bowman, Coull, Currie, Ewing, Fisher, Henry,
Johnston, Kerr, Lunan, McAdam, McLaren, Mitchell, Moir,
Storrar, and Strachan.
Apologies for absence were received from Messrs. Davidson and
Kermath. The minutes of last meeting were read and approved.
The Assistant-Secretary read the report of the General Purposes
Committee, from which it appeared that intimation had been re¬
ceived from the Royal College of Physicians, Edinburgh, that the
transference of their materia medica museum to the Society had
been finally approved, and the Committee had made suitable
arrangements for its removal from the College to the Society’s
House, and the work was in process of being carried out. It was
also reported that the Committee had completed the purchase of
the Scoresby- Jackson collection of materia medica for a sum of
£45, of which £27 16 s. had been privately subscribed, and the
balance of £17 4s. had been paid by the Society. A committee
had been appointed to arrange for the suitable placing of the
collections in the Society’s Museum.
On the motion of the Chairman the report was unanimously
adopted.
The Executive then went into committee to consider the annual
report to the Council.
On resuming, the report was unanimously approved of on the
motion of Mr. Coull, seconded by Mr. Lunan, and ordered to be
forwarded to the Council.
Membership oe the Society.
Mr. Currie then moved the following resolution : —
“ That all chemists and druggists should be eligible as members of the Phar¬
maceutical Society, and that steps should be taken to secure a short Amend¬
ment Act to effect this object."
Mr. Currie said : In submitting the motion which is on the
billet calling to-day’s meeting I am quite aware I attempt nothing
very new, but yet I consider it very important. Most of you will
admit that if, by any reasonable means possible, you could improve
your individual position, such plan would be adopted and put into
execution. What is desirable for the individual, therefore, is surely
much more so for a corporate body, and especially so when opinions
have already been expressed in favour of the proposal. I have been
induced to bring forward this matter now simply because I look
upon it as a matter of justice and of such importance that the sooner
some such reform is carried out the sooner will the Pharmaceutical
Society receive that amount of general support which is necessary
to obtain success in Legislative matters which may be brought
forward. In order that some idea may be had as to the
number of chemists in the country, those given by the Registrar
for last year are as follows: — There are 15,166 individuals on
the Register. Of that number only 4825 belong to the Society,
and of that 4825, 3841 are in business. Of pharmaceutical chemists
there are 2253 on the Register, 1584 of whom are members of the
Society, a fair proportion perhaps, but it should be better. There
are 12,913 chemists and druggists on the Register, but only 3241
are connected with the Society. Now, why is it that since the
Minor is recognised as the legal qualification those who
possess it do not enjoy the privileges of the Society from which
they obtained their diploma ? The Major graduate is no better in
the eye of the law. He contributes no larger annual or life fee to
the funds of the Society, but because he has obtained a higher
grade certificate (as it were) he alone is entitled to membership
and its privileges. Gentlemen, democratic ideas are on The
increase, and the Uitlanders must be recognised as a power to be
dealt with, and I say it without fear of contradiction, that until
the privileges of the Society are open to every chemist and druggist
who is connected with it, so long will the Society drag its weary
way, and instead of advancing will be more likely to retrograde.
I have heard it stated that by admitting chemists and druggists as
members of the Society, and granting them privileges as such,
that the position of the pharmaceutical chemist would be lowered
somewhat, and that he would not obtain that reward for his extra
study to which he was duly entitled. If such ideas prevail I have
very little regard for the individuals who hold them. All honour
to those who take the Major qualification, but it does not neces¬
sarily follow that the passing of that examination makes a man
May l, 189^.]
PHARMACEUTICAL JOURNAL.
373
better fitted for business, or better able to judge of the necessities
of the times. I do not see that the position of the pharmaceutical
chemist would be interfered with one iota. Now that the Minor
qualification demands so much careful training and increased
knowledge, and when we remember that it was not always of such
extent, and that its present requirements are almost equal to — if,
indeed, they do not exceed — the Major requirements of many years
ago, we cannot but wonder at the far-sighted vision of the late
Mr. Sandford in contending for this very same object in 1867, when
he said that the Minor examination would not always remain as it
was, that it would be progressive, and that it would yet be a
qualification deserving of recognition of full membership of the
Pharmaceutical Society. Such time, I submit, has now arrived,
and it is desirable in the interests of our calling, as well
as in the interests of the Society, to make the attempt to
consolidate what up till now has been a disunited body.
The question then arises as to how it could be accomplished. All
previous attempts at legislation have been so loaded with con¬
troversial and debatable matters, that the moment the Bill sees the
light of day its doom is sealed. I think the tactics of the Pharma¬
ceutical Council have been wrong in bringing forward Bills as
practically complete which have not been properly discussed,
which in fact were hatched in a hurry, and such being the case,
premature death was sure to follow. If they would submit matters
and allow them to lie on the table for six or twelve months to be
discussed on the merits, I am of opinion greater success would
follow. But as to the matter in hand, a short Amendment Act,
dealing with this matter alone, not touching other questions at all,
no matter how desirable — would, I think, be the best. Let this
clamant matter be attended to first, and in such a way that it
will meet with the approval of all connected with pharmacy.
You may say such a question is not worth the candle,
well I am of a different mind. During the correspondence which
took place in connection with the 1894 Bill, one correspondent put
it that the Society had been in labour for a very long time and
had brought forth such a very small mouse that it did not matter
much whether it lived or died. I have great faith in small things
to begin with, and if the Pharmaceutical Council can only conceive
agAin and bring forth a very small Bill, devoted to this matter
alone, and successfully carry it through, it would clear the way
for greater things afterwards. You are all familiar with the fable
of the lion and the mouse — how the small mouse by being spared
was able to accomplish a very great feat by setting free the king of
beasts — so in like manner the small Bill, by offering some
inducement to chemists and druggists of Great Britain to join the
Society might be productive of great results, and the consolidation
which we all so much desire might become an accomplished
fact.
Mr. Lunan said he had great pleasure in seconding this motion.
He did so partly as a pharmaceutical chemist and as one who
thought that nothing would be lost to the holder of the Major
certificate by allowing associates to become members of the
Society. He thought the figures which Mr. Currie had given
them should convert them all to his ideas. If it was expedient
that this method should be taken, he had gone a long way to
prove that it was right. Of 2253 pharmaceutical chemists, 1584 —
about 75 per cent. — were members of the Society. Of course
the question of expediency had always to be considered. In
regard to moving the Executive in the matter, the action they
had taken in regard to the Preliminary examination had had an
important effect on the Council in London. What they had
urged must have apparently been taken to heart there and
seriously considered. The movement for entertaining this motion
of Mr. Currie’s was perfectly in order and perfectly right on the
ground of expediency. In seconding the motion he wished to
ask Mr. Currie if he would make men members of the Society
whether they were in business or not immediately on paying their
subscription.
Mr. Currie said that every individual who held a certificate
should be a member of the Society on paying the subscription.
Mr. Lunar said that at present Major men became eligible on
paying their guinea instead of half a guinea and became full mem¬
bers. If the motion were carried into effect, Minor men, whenever
they passed, must pay their guinea and then they would become
full members.
Mr. Storrar said he had no intention whatever of moving an
amendment to this motion. As Mr. Currie had said, it was not
entirely new. It had been before the Society for some time and
practically adopted by the Council, although they had as yet
taken no action with reference to the question. As some of the
members there knew, up till now he had been rather against the
proposal, and he wished to make a statement of his position, which
had come about partly on account of Mr. Currie’s eloquence and
partly also, he believed, on account of his being in a minority of
one in the Council on the subject, and he intended now to give
what help he could in favour of the proposal. He was mainly con¬
vinced by Mr. Currie’s arguments in this way — that they had not
the slightest weight with him ; in fact, he was more convinced by
what Mr. Currie had not said rather than by what he had said.
He began by advocating this as an act of justice, but he would
ask justice to whom? If it was justice to the chemists and drug¬
gists it was injustice to the Major men. Mr. Currie followed that
up by saying that he also believed the Society would have a large ac-
cessionof new members, that men would join and giveitthe support it
deserved. Did Mr. Currie mean that men who were not members would
come in now, and that men who were associates in business, by be¬
coming members, would support the Society any more strongly on
that account ? He did not see it. He could not for the life of him
see how the best men, who at present could become members of
the Society, but declined to do so, would be induced by the very
empty honour of being a member instead of an associate in business.
The argument in favour of this was that it would give them, on the
Council and elsewhere, the very great benefit of men not eligible^
for the Council at the present time. That was a very strong argu¬
ment in favour of Mr. Currie’s motion. He never had any objection
to that, but he did object wholly to these matters or suggestions,
being taken up piecemeal. They had any amount of amendments
to make to the Pharmacy Act, but their policy for a great many
years had been a purely stop-gap policy. Honestly speaking, he
did not think it was really worth while going to Parliament for the-
sole purpose of making associates in business members of the Society.
It was a very small matter to go to Parliament with. What the
policy of the Society should be was to formulate in a proper Bill
what reforms they thought were necessary and to act, and let the
legislation or attempted legislation be on the lines of carrying out
a previously-fixed-upon policy. He thought they should attempt tc
push forward more important matters than this, to his mind, com¬
paratively trifling amendment. But this policy appeared to b
the policy of a very large majority of the Society and of the Council,
and he was perfectly willing to go in with it.
Mr. Kerr, Dundee, said he would like to give Mr. Currie his
support in this matter. His ideas were on the line of strengthening
the Society, and the great idea at present was to strengthen the
Society and get more members to join. He stated his experience
of endeavouring in the Dundee district to get more members to
join the Society. He succeeded in getting thirteen. But he had
to call again for their annual subscription, and he found that the
feeling was not very much improved. One grievance among them
was the difference between men who were in business in 1868 and
those who, having passed since that date, had passed an examina¬
tion but were only associates in business. One associate not only
pointed to the title “ Member of the Pharmaceutical Society ”
above his neighbour’s door, but also to the intimation thereon,
“Prescriptions dispensed at reduced prices.” He (Mr. Kerr)
thought on the whole that a short Act was wanted here as a desir¬
able thing. He knew there were difficulties in the way. He
thought Mr. Storrar put the case very well, but he thought this
matter should be kept separate from the other things.
Mr. David McLaren said that if Mr. Storrar had objection to
this Act on the question of expense, he had no hesitation in saying
this, that if they went up unanimous on this question, desiring
that all should become members of the Society, a short Bill
would not cost a single penny. The Government would at once
accept it and take it up. A good deal had been said from time to
time as to the importance of giving equal privileges to the Associates
who had passed as to the Major men. He thought that was impor¬
tant if for no other purpose than having some controlling power in
the business of the Society in London. At present it was said they
were not allowed to have any say, but that if they had, or if they were
members of Council themselves, they would be able to manage the
affairs of the Society better. At the same time the question of
expense was not one that need be considered here. If contentious
business were introduced into the Bill it might get a good deal of
opposition, both in the House itself and outside, and they might
possibly ruin the whole Bill. But if they got the united body of
chemists and druggists to go forward by-and-bye with the other
amendments proposed they would not be long in carrying a new
Act.
374
PHARMACEUTICAL journal.
[Mat 1, 1897
Mr. Moir, Glasgow, said he sympathised very much with what
Mr. Kerr had said in reference to collecting subscriptions. They
could not have taxation without representation now. He fre¬
quently got that in his teeth when going round for subscriptions.
The time had come when the doors of the Society should be open
to everyone. It was not justice to ask a guinea from anyone
without giving him a voice in the affairs of the Society. The only
objection he had was that supposing the Pharmaceutical Society
went to the House of Commons with this small Bill, would it be
the means of shutting the door to them in the near future ? for
undoubtedly they required many more and better reforms than
this. If it were the case that by going to Parliament just now
they would get the door shut against them in the near future, he
would be in favour of allowing this to drop. But if they went
forward with it he would like tacked on to it that they ought to
have divisional representation in all the districts. They would
thus be more closely in touch with the Council, which they could
never be by having affairs carried on as they were at present. If
they had a member of the Council in the west of Scotland it would
be a great inducement for all the chemists to become members,
and they would keep him posted up and screwed up if necessary.
Mr. Coull suggested that that part of the proposed resolution
proposing a short Amendment Act should be dropped. As a pharma¬
ceutical chemist he quite approved of the proposal to admit all
chemists to membership.
Mr. C. F. Henry thought it was a very strong point in support
of the proposed Bill that it dealt with only one thing. The
moment they began to introduce two or three subjects into their
Bill the result would be that opposition would arise, and it would
go no further. They wanted a great many things which might be
embodied in a comprehensive Bill, but when would they get it
passed ? He did not think they would ever get it in one Bill. But
if they put forward a small part every year and kept always at it
they would have far more chance of getting measures passed.
Otherwise they would have five, ten, or twenty oppositions to the
Bill. He supported the idea of having this single measure in a
short Bill.
Mr. Johnston, Aberdeen, in support of the motion, said he
believed it was the very best thing the Society could do to take in
all examined men. By that means the membership of the Society
would be increased from two or three thousand to fifteen thousand
strong. Then he said they would be able to go forward with any
Bill and get it passed. The sooner it was done it would be better
for the trade in the country. Mr. Kerr had referred to the trouble
he had with men speaking about what they got for their guinea.
They said they had no voice in the affairs of the Society, but that
was a mistake. They had a voice in the representation for Scot¬
land, which he considered no small matter, seeing they sent such
representatives as his colleague and himself. He had great
pleasure in supporting Mr. Currie’s motion.
The Chairman said he cordially supported Mr. Currie’s mo¬
tion. He regarded it as a matter of justice to the chemist and
druggist associates in business, and he thought it was right that
they should be represented on the Council. With regard to the
uestion of the representation of the two classes of chemists and
ruggists and pharmaceutical chemists on the Council, that was
the chief point on which the discussion turned at the Annual
Meeting in London when this subject was before the Society on a
former occasion. At that time he was quite prepared to have
acquiesced in the proposal as to the proportional representation,
but thinking the matter over since, he had come to the con¬
clusion that there was very little in the restriction, and too much
had been made of it. The electors might be trusted to elect the
best men, and there was no good reason for any restriction. They
had a standing example of how the matter worked in that Executive,
on which they had always been able to secure the election of good
men, and they had no restriction as to whether a man was a
pharmaceutical chemist or a chemist and druggist. All he could
say further was that he thoroughly approved of Mr. Currie’s motion,
and more especially he wished to distinctly emphasise the fact that
there should be a short Act passed embodying the proposal in the
motion and limited to that. Until that Act was passed he did not
thiqk the Society could be put upon a proper basis.
Mr. Currie, in reply, said he did not think with Mr. Storrar
that to open up the Society as he proposed would be an injustice
to pharmaceutical chemists. They had quite as good men, and
in a great many cases, without saying anything too strong, better
than those sitting at the Council Board. He said that without
any hesitation, and he did not think it too strong. Mr. Storrar
did not think any good would result from opening their doors to
all and sundry. He (Mr. Currie) happened to know the minds of
a good many members in the west and throughout Scotland, and
he was bound to say that if an amendment of this kind were
passed they would certainly have five-sixths of the chemists and
druggists in connection with the Pharmaceutical Society of Great
Britain. They had received the motion he had given notice of
very agreeably to him. He had no notion as to how opinion would
go, but he had resolved to leave it entirely in their hands.
The resolution was unanimously adopted.
Annual Election of Executive.
The Chairman moved that the next election of the Executive be
fixed for June 18, and that the Chairman and the Vice-Chairman be
the scrutineers of the voting-papers, with power to add to their
number. This was agreed to.
The Glasgow Conference.
Mr. McAdam, Glasgow, gave in a report as to the arrangements
for the British Pharmaceutical Conference to be held in Glasgow in
August. He stated that on the Monday, as usual, the President
would receive the members in the Corporation Galleries, which had
been kindly granted by the Corporation. These rooms, he said,
were very suitable for such a purpose, and very near the Grand
Hotel at Charing Cross, their headquarters. On Tuesday they
would meet in the large hall at the Grand Hotel, very suitable for
them, and the Lord Provost would welcome the members. After
that papers would be read by members. An excursion would be
organised for Loch Lomond, leaving about four o’clock. On Wednes¬
day morning they would have business as usual. In the forenoon the
ladies wouldgetadrive through the city and visitpublic places, and in
the afternoon the excursion would go in brakes and inspect the water¬
works at Milngavie and drive back in time for the smoking concert and
the ladies’ drawing-room concert at the hotel. On Thursday they
would take train to Greenock and leave there about nine o’clock
in the “ Glen Sannox,” the best steamer on the Clyde, for a sail on
the Clyde. They would cross to Hunter’s Quay and pass Dunoon
and Inellan, go down to Rothesay, up the Kyles of Bute, and
round the other side of Bute, up Loch Long to Arrochar, then
back, and if time permitted, up the Gareloch and back, to
Greenock, which they would reach about seven o’clock.
The Chairman said they were much indebted to Mr. McAdam
for this intimation as to the Conference arrangements. In
Glasgow they possessed almost unequalled facilities for making
such a meeting as this an interesting and attractive gathering. He
hoped their southern friends would take special note of this, and
if they attended in large numbers he felt sure they would find
that admirable arrangements had been made. He hoped the day
fixed for the cruise would be fine. That was the only condition
necessary to make the day a most enjoyable one to all who had
the opportunity of being present.
The meeting then closed.
NOTES AND FORMULA:.
To Prevent Rusting of Instruments.
Levai finds that a most efficient means of preventing rusting of
instruments is 0-23 per cent, of pure sodium hydrate, containing
no sulphur, added to boiled water. The instrument should lie in
this solution during the operation. Sharp knives do not lose
their edge in the faintest degree. — Thera. Gazette [3], xiii., 56.
New Fixing Solution for Vegetable Tissues.
The following liquid is said to rapidly penetrate vegetable
tissues and to fix them, without causing contraction : — Mercuric
chloride, 5 ; potassium bichromate, 2J ; sodium sulphate, 1 ;
glacial acetic acid, 5 ; distilled water, 100. — Zenker in “Micro¬
graphic Prepar.” (L’ Union Pharm., xxxviii., 72).
Mouthwash Tabloids.
Bernegan gives the following instructions for the preparation of
these by means of tabloid machine No. 1 : —
Heliotropinum . . . 1 centigramme
Saccharinum . 1 ,,
Acidum Salicylicum . 10 centigrammes
Mentholum . 1 gramme
Saccliarum Lactis . . 5 grammes
Spiritus Rosae . . . . q.s.
Ut fiant tablettse, nr. 100
The tabloid basis may be coloured red with eosin, green with
chlorophyll, or blue with indigo-carmine. — Pharm. Centralh.,
xxxviii., 141.
May 1, 1897]
PHARMACEUTICAL JOURNAL.
375
REVIEWS AND NOTICES OF BOOKS.
A Contribution to the History of the Respiration of Man.
By William Marcet, M.D., F.R.C.P. , F.R.S. Pp. 116.
Price 12s. M. London : J. and A. Churchill. 1897.
This handsome quarto volume includes the Croonian lectures
given by the author in 1895, together with an additional part
entitled the “ Methods of Investigation and Analytical Results,”
which gives a scientific exposition of the lectures. The lectures,
which represent the outcome of twelve years’ continuous work
(1883-1895), have already been noticed in this Journal
The lectures themselves are full of matter expressed in such a way
that it can be enjoyed and assimilated by anyone who has some
knowledge of and taste for the physiology of respiration. The
appendix is of a more technical character, and will be invaluable
to those who may undertake similar researches in the future.
In the earlier observations taken in the Alps indiarubber bags
were used for collecting expired air, but it was found that
there was a loss of C02, due to diffusion through the indiarubber1
In consequence of this bags made of indiarubber faced with oiled
silk were adopted, and it was found that the loss of C02 was con¬
siderably diminished. The expired air was conducted to the
receiver by a face-piece made on the principle of a Clover s ether
inhaler. The presence of the face-piece was found to increase the
quantity of expired air in experiments carefully conducted in the
laboratory. The use of the face-piece also increased the amount
of C02 in the expired air. This was attributed to “the increased
labour of the respiratory muscles, due to a sensation resembling
that of breathing rarefied air, though really produced by the re¬
breathing of a small portion of the air expired.” This was due to
the impossibility of removing from the cavity of the face-piece
the small , quantity of the expired air which it contained.
The graphic method was applied to record the results of the
laboratory experiments. The expired air was collected in a bell-
jar suspended over water in such a way that no effort was
experienced when raising the bell-jar at each expiration. The
upward movements of the bell- jar were recorded by a style on a
chart stretched over a revolving drum. The tracings gave a
graphic record of the number of expirations and of the volume of
air expired in a given time. The method served admirably to
record observations relating to the chief objects of the research,
viz., to ascertain the influence of volition on respiration, the effects
of breathing air from and into closed vessels, and of the breathing
air mixed with oxygen, hydrogen, and carbonic acid. Dr. Mar-
cet’s book will always remain an important member of the classics
of the subject with which it deals.
Anatomischer Atlas der Pharmacognosie und Nahrungsmittel-
kunde. By I)r. A. Tschirch and Dr. 0. Oesterle. Parts 9, 10,
and 11. Price Is. 6cZ. each, nett. London : Williams and Norgate.
For the past quarter of a century a succession of eminent histolo¬
gists have devoted a large portion of their time to the study of the
structure of the principal cereals and leguminous seeds, and to the
comparison of the most important starches with one another. The
authors of the ‘ Anatomical Atlas ’ have made a renewed and
thorough investigation not only of the structure, but also of the
development of the principal cereals (barley, wheat, maize, rye,
oat, and rice) from the young ovary to the ripe fruit. The
anatomy of the glumes, awn, palese, pericarp, integuments,
and nucleus is minutely described, as well as the changes that
these parts undergo during the ripening of the fruit, so that a
complete account of the structure of each of these fruits, and the
morphological nature of the tissues they exhibit is here furnished.
In this group, more than in any other, the value of placing before
the reader sections of the young and of the ripe fruit, together
with the various layers in succession that can be found in the
latter, is most conspicuous, as indeed any student of the subject
may easily convince himself by comparing the plates in the ‘Atlas’
with the illustrations previously published by other histologists.
The investigation of the development of wheat fruit has shown that
the outer part alone of the layer considered by Moeller to be the
seed-coat is really the integument, whilst the inner is the
remains of the nucellus (perisperm). This seed-coat is developed
from the inner alone of the two integuments of the seed, the outer
collapsing soon after pollination, and perishing so completely that
no trace of it is to be found in the ripe fruit. The ‘ ‘ tubular
cells ” that have long been known are shown to be the remains of
the inner epidermis of the pericarp, the cells of which become
separated from one another.
The anatomy of maize and rice is equally minutely described.
In the oat the pericarp is very' much reduced, owing, probably, to
the protection afforded by the paleaa ; in barley, in which the palese
are adherent, a similar reduction takes place. In the ripe oat only
the epidermis and five rows of degraded cells are to be found. The
integuments and nucellus suffer similar absorption, which, in fact,
appears to proceed to a greater extent in this than in any other
cereal.
In Part 10 the anatomy of ergot, the seed of the Corncockle ( Agro -
stemma githago), and the Field Cow-wheat ( Melampyrum arvense),
which are liable to be found in the meal of the cereals, is dealt with.
The colouring matters of ergot, which form an important means of
recognising it, are, according to the authors, produced in a single
layer of cells, which, though not originally the outer layer, becomes
so by the exfoliation of those beyond them after the secretion has
taken place. From this layer of cells the colouring matter finds
its way into the neighbouring cells, and may even permeate, more
or less, the whole ergot.
Following upon this is the anatomy of the leguminous seeds
( Pisum sativum, Phaseolus vulgaris, P. multiflorus, Ervum lens ).
In these, the development of the characteristic thick-walled
palisade cells of the epidermis is studied, and the thickening is
shown to be effected at the expense of the starch produced in the
third and succeeding layers of cells, which therefore collapse.
The dark and light zones so frequently seen in the palisade epidermis
of leguminous seeds are produced probably by differences in the
chemical composition of the cell-wall, since these portions react differ¬
ently with chlor-zinc-iodine. Below the fissure along the hilum, com¬
monly exhibited by these seeds, is a strand of tracheids, which the
authors regard as a means of conveying water rapidly to the radicle.
This part (10) and the succeeding one (11) contain new drawings
of the most important starches. Part 11 concludes with the
anatomy of galangal, zedoary, and the true and false star anise.
In the case of the latter, the authors endeavour to show that
histological characters can frequently be utilised to distinguish
between the allied fruits ( Illicium verum and I. rtligiosum) when
the macroscopic characters leave one in the lurch. In the shape
and size of the palisade cells of the epidermis, in the position in
which the longest are found, and in the transition forms they
show, the authors find distinctive features. But the most
marked differences are exhibited by the aleurone grains. These
are not nearly so numerous in the true as they are in the false ; in
the former they are irregular in outline and seldom contain crys¬
talloids, though they enclose numerous globoids ; in those of the
false they are oval, smooth, contain one or several crystalloids, as
well as numerous globoids. Unfortunately, the seed is compara¬
tively seldom developed, so that this means of distinguishing the
two species loses much of its value.
376
PHARMACEUTICAL JOURNAL.
[May 1, 1897.
PARLIAMENTARY NOTES AND NEWS-
Parliament has resumed its sittings, but the spirit of Easter¬
tide seems to still exert a strong influence on honourable members,
and to render them disinclined for sustained effort. Monday and
Tuesday were signalised by “counts out” at a very early hour,
but several Government measures wrere advanced a stage before
the House rose. Exceptionally good fortune seemed to await the
Early Closing Bills on Tuesday. There was no Government busi¬
ness, and Sir J. Lubbock’s Bill occupied the first position on the
order paper, being immediately followed by the Shops Bill of Sir
Charles Dilke. What could be wished for more favourable ? But
after talking about Crete, and checkmating Sir Howard Vincent’s
attempt to resuscitate “protection” in a new guise, the House
preferred to give a practical expression of their sympathy with
early closing by going home rather than to discuss in the abstract
the principles embodied in the Shops Bills.
The Incorporated Law Society, like the Pharmaceutical
Society, has statutory duties to perform, and there appears to be
common ground for complaint that these duties are frightfully
expensive at times. In the case of the Law Society there is a
disposition to draw attention to their particular grievance, and
they have secured the Parliamentary assistance of Mr. C. Harrison
(Plymouth), Mr. W. Ambrose (Harrow), and Mr. A. Helder
(Whitehaven), all of whom have given notice to move resolutions
relating to the expenses incurred by the Society in performing
certain duties imposed upon them by Act of Parliament. The fact
of the lawyers being able to make known their woes to the House
in triplicate is almost enough to inspire envy in the hearts of
chemists 1
Official Delay. — The Vaccination Commission sat many years
before venturing to report finally on the subject referred to them,
but they did issue that final report in August last, and it was
fondly hoped that the whole of the minutes of evidence would be
available by the end of last year. The delay in the publication of
the remaining records may be quite unpremeditated, but General
Laurie (Pembroke and Haverfordwest) will on Friday, the 30th,
try to elicit from the President of the Local Government Board an
explanation as well as a date when the belated appendices and
minutes of evidence may be expected to appear.
Rhea Fibre. — Consul Playfair, of Ningpo, China, in his report
for the year 1896 on the trade of that port, refers to the stimulus
which has been given to commercial interest in Rhea by the dis¬
covery of a new method of decorticating the fibres (see Ph. J.,
June 13, 1896, p. 478). Applications for seeds and young plants
have been made to Mr. Playfair, under the impression that
Ningpo was a centre of the grass cloth industry, and though this
is no longer true, the Consul, with some difficulty, procured from
a native agriculturist a small quantity of seed with a view to
essaying the introduction of the plant into the Straits Settlements.
His Singapore correspondent reports that the seeds germinated
readily, but that the early sprouts had more the look of cannabis
than of boehmeria. The contretemps is attributable to the similarity
between the native Chinese names for the two plants — Chu-ma and
Hu-ma. There seems no reason why Rhea could not be profitably
cultivated at Singapore ; but Mr. Playfair advises that it is better
to obtain seeds from Wenchow or Formosa, where the fibre is still
an item of manufacture.
LITERARY NOTES.
* The Chronicles of Christopher Bates ’ is of pharmaceutical
interest inasmuch as the book is written by a chemist’s assistant,
as Mr. Ebenezer Rees is modestly content to style himself. Other¬
wise, these ‘ ‘ notes on the life of a peculiar mortal ” will appeal to
the craft no more than to other members of the general public.
The book is well written and should attract many readers, who
will doubtless agree that whether the * ‘ peculiar mortal ” actually
existed or not, what is related concerning him possesses all the
force of realism. Human joys and sorrows are depicted by the
author with a skilful hand, and in a way that secures the sympathy
of those before whom his characters parade.
The ‘ Kodak News ’ for April is distinguished by a beautiful
process reproduction of a view of the font in Lichfield Cathedral,
taken with a short focus lens, and the rules to observe in photo¬
graphing such subjects are clearly enunciated by W. Ethelbert
Henry. In addition, there are brief articles on “ Some Troubles
and their Causes,” “ Cyclo-Photography,” and “ The Bull’s-Eye
Camera in the Soudan.” The numerous illustrations are, as
usual, beyond criticism.”
‘ Moring’s Quarterly ’ contains, in its third number, the first
instalment of an excellent illustrated biographical sketch of Albert
Diirer, together with an appreciation of Ford Madox Brown’s work
and influence on Art, descriptions of the Laud M edal and of the
Arms of the City of London, and various notes of interest on the
subjects of which it specially treats.
Photography in Colours is much to the fore at present, and
those who are interested in the subject will find some contributions
to its bibliography by Thomas Bolas of considerable value. The
article appears in the Journal of the Society of Artsiov April 23, and
serves as the basis of a tolerably exhaustive index to what has been
published on photography in colours, beginning with Seebeck,
Niepce, and Herschel’s work early in the present century and
bringing the matter up to date.
Schimmel’s Semi-Annual Reports, which deal mainly with
essential oils, are wonderful productions, more especially when
regarded from a purely commercial point of view. Twice a year
some fifty or more pages appear, first in German and then in
English, brimful of suggestive hints and information of practical
value respecting essential oils and various synthetic preparations.
That the preparation and distribution of these reports benefit the
firm cannot be doubted, but whether a similar result would
accrue in the case of a British firm may be doubted, apart from
which the experiment is not likely to be tried, and so we can only
admire the enterprise of which the publications are indications
and regret its absence nearer home.
Lean’s * Royal Navy List ’ for April records all navy and
army news up to date, including details of special service during
the past three months, recent decorations and causes of special
promotion, etc. , etc. Anyone requiring information on any point
regarding the navy and army or officers of either force may depend
upon finding it in this list, which is published quarterly by Messrs.
Witherby and Co., High Holborn, W.C., at seven shillings and
sixpence.
Max 1, 1897]
PHARMACEUTICAL JOURNAL.
377
Pharmaceutical Journal.
ESTABLISHED 1841.
Editorial Office : 17, BLOOMSBURY SQUARE, W.C.
Publishing aqd Advertising Office : 5, SERLE STREET, W.C.
LONDON: SATURDAY, MAY 1, 1897.
A CASE OF REVERSION.
It is a matter of history that when the founders of the
Pharmaceutical Society initiated the system of pharmaceu¬
tical examinations, which has been maintained with modifica¬
tions ever since, the idea they had in view with regard to
the different stages was that the Minor examination should
be a test that the period of pupilage had been profitably spent
and the erstwhile apprentice competent to act as an assistant ;
and that the Major examination should be the qualifying
-examination, the passing of which ought to be incumbent on
-everyone proposing to practise pharmacy on his own account.
It is also a matter of history that when the President and
Council of the Society proceeded to take steps to enforce
those views in the case of all persons entering the craft, they
had to face a little world in arms amongst those
already in the trade, and the opposition raised
was deemed so serious that a compromise was agreed
to in order that the Bill before Parliament should not
be totally wrecked. As a result, the Pharmacy Act of 1868
left the Minor examination in the position of being the sole
test required prior to registration, and the passing of the
Major examination, whilst it indicated an acquaintance with
the higher branches of the subjects in the pharmaceutical
curriculum, carried with it no advantages as a practising
pharmacist not possessed by chemists and druggists.
But time, as Schiller has it, is a wonder-working god, and
now, after the lapse of thirty years, a desire is finding ex¬
pression for a special intermediate examination which may
serve as an indication that the holder of the certificate is
properly qualified to act as a chemist’s assistant. This
desire has been voiced on many occasions by correspondents
of the Pharmaceutical Journal , and it is only natural thaG
similar ideas on the subject should suggest themselves to
many individuals, for undoubtedly a rational system
of pharmaceutical organisation seems to require, in
the public interest, that each person engaged in a
pharmacy should have proved his fitness to undertake the
work that will fall to his share in the ordinary course. Mr.
John McMillan, therefore, advanced no new idea in his
letter to the Journal published a fortnight ago ( ante ,
p. 345), when he referred to Mr. Kerr’s suggestion
that “ it might be wise for the Pharmaceutical Society
to obtain powers to have an assistant’s qualification.” The
special interest attaching to his communication lay in the fact
that one who was in business before the passing of the 1868
Act, and has been a member of the Pharmaceutical Society
almost ever since, should have felt impelled at this late period
to put on record his concurrence with the views of our
founders, his long business experience having convinced him
that, in so far as the original plan has been departed from, to
that extent pharmaceutical organisation is deficient to-day.
But whether the proposal to institute a lower qualification
— which shall entitle its possessors to do everything but keep
open shop on their own account — would now commend
itself to those who first organised British pharmacy is quite
another question, and to judge from their recorded opinions
the answer to this question would be a decided negative.
Having arrived at the present position, where the passing of
the Minor examination and subsequent registration are held to
be legally necessary in the case of everyone engaged in per¬
forming certain special functions of pharmacists, it would he
extremely undesirable to hark back and open the way to
possible abuse by reducing the legal requirements. Any
assistant who is worth his salt should be quite capable of
passing the qualifying examination within a reasonable
period of completing his term of pupilage, and as one
correspondent observed in last week’s Journal, the
assumed scarcity of reliable chemists and druggists
willing to act as assistants may be due, when apparent, to a
natural reluctance on the part of legally qualified men to
accept positions at unreasonably low salaries. From the
assistant’s point of view, as from that of the public, the
higher his qualification the better it most certainly is for
himself, and employers who act on a similar assumption may
rest assured that advantage will not be lacking in their
case. Assistants should be encouraged to qualify at the
earliest possible opportunity, and the exertion of any
influence that may tend to the more universal possession of
a higher rather than a lower qualification on their part cannot
fail to benefit pharmacy as a whole.
THE MERCK PHARMACY.
In a letter accompanying a description of Messrs. Merck
and Co.’s new premises in New York, Mr. W. C. Alpers
truly remarks that the opening of a “ drug store ” is, as a
rule, of no particular significance, except to the immediate
vicinity, and does not deserve any further notice. He
claims, however, for the establishment of which he is the
manager, that it is “an institution of national scope,
destined to be a mark-stone in the development and
advancement of American pharmacy.” The description sent
may be regarded as fully justifying this hold claim, and the
firm is to be congratulated on totally and courageously
breaking loose, as the writer expresses it, from all those tradi¬
tions and customs which have hampered pharmacy in the
past, and on boldly setting out as professional men, to
conduct professional work only. The Merck pharmacy is
completely fitted with the most modern scientific apparatus
and, in addition to providing the best possible service for
the sick under medical orders, it is intended to help other
pharmacies to do likewise. There are pharmaceutical,
analytical, microscopical, and bacteriological laboratories
fully adapted for carrying out necessary investigations, testing
stock, and executing analyses. The business needs of other
pharmacists will be met by the firm in every possible way,
and apart from anything else, free information and advice
are offered on any perplexing question or difficulty occurring
in the regular run of professional work. There may, of
course, be reasons unknown to us why this offer of assistance
may not be appreciated by A merican pharmacists, but it is a
pleasure to be able to record that the entire resources and
facilities of a model pharmacy on a scale of unparalleled
completeness are cheerfully and cordially placed at the
service of other pharmacies throughout the land.
378
PHARMACEUTICAL JOURNAL.
[May 1, 1897.
ANNOTATIONS,
A Special General Meeting of the Pharmaceutical Society
■will be held at 17, Bloomsbury Square, W.C., on Wednesday,
May 19, at the conclusion of the business of the Annual General
Meeting, for the purpose of abrogating Bye-laws 11 to 24,
Section X., and considering the proposed new Bye-laws (see ante,
p. 315) which will be submitted by the Council. The draft Bye¬
laws will previously have been read three times at meetings of the
Council, in accordance with the provisions of the Society’s Charter
of Incorporation, and, if confirmed and approved at the special
general meeting, will then only require the sanction of the Privy
Council to give them legal force. The second reading took place
at a meeting of the Council held on W ednesday, a report of which
appears at page 372.
The Glasgow Conference Programme, as detailed by Mr.
McAdam, at the meeting of the Executive of the North British
Branch last week, is an exceedingly attractive one. The head¬
quarters of the Conference will be the Grand Hotel, but the recep¬
tion by the President — Dr. Charles Symes — is to be held in the
Corporation Galleries, the use of which has been kindly granted by
the Glasgow Corporation. The members will assemble for the
business meetings of the Conference in the large hall of the Grand
Hotel, and there they will be welcomed to the city by the Lord
Provost. The excursions include one to Loch Lomond on the
Tuesday afternoon, visits to the waterworks at Milngavie and to
other public places on W ednesday, and a sail on the Clyde and up
the Kyles of Bute on Thursday. If in addition, our Glasgow
friends can secure a promise of fine weather and a temporary
cessation of their noted rain-showers, the prospect of enjoyment
will be great.
The Council of the British Medical Association has awarded
its gold medal for distinguished services to Sir Walter Foster, M. P. ,
who has won the distinction by his services to the profession in
Parliament, and (as a member of the late Administration) at the
Local Government Board. The medal has been awarded only
seven times previously— twice for distinguished gallantry in the
field of battle by Army surgeons, twice to civil practitioners for
courage exhibited in rescuing coal miners after explosions, once to
the late Dr. Parke for his devoted services with Mr. Stanley’s
Expedition in Africa, and twice for public services to the pro¬
fession — in 1880 to the late Dr. W. Farr on perfecting the system
of vital statistics in this country, and in 1886 to the late Dr.
Edward Waters for his efforts in the cause of medical reform.
Amongst Sir Walter Foster’s other claims to public recognition
are the services rendered by him in coping with the cholera inva¬
sion of 1892 and 1894, and as a member of the General Medical
Council for ten years.
The Public Analyst versus Somerset House conflict seems
to be unending. An instance of this, in which a pharmaceutical
chemist was painfully interested, occurred at Brentford Police
Court a few days ago, and was reported in last week’s Journal.
Now a Dalston milk dealer has provided the bone of contention.
This individual was summoned for selling milk adulterated with
six per cent, of added water, but the certificate of the public analyst
for Hackney (Mr. Leo Taylor) was disputed, and the remaining
sample was forwarded to Somerset House for analysis. The result
of this analysis was that the sample was pronounced pure. At
the adjourned hearing, Mr. Otto Hehner, Dr. Bernard Dyer, and
Mr. Edward Bevan were called in support of the prosecution, and
all expressed the opinion that the adulteration varied from five to
seven per cent. It was stated during the hearing of the case,
although that hardly seemed necessary, that the Somerset House
chemists did not work in harmony with the public analysts, and
ultimately the case was further adjourned for the attendance of
the Somerset House chemist.
Plymouth and the Neighbouring Towns are witnessing the
unedifying spectacle of what is referred to by the local press as
the institution of a boycott by local medical men. For some
reason or other the management of the Three Towns Friendly
Societies Medical Institution has been condemned as lowering the
dignity of the profession, and at a meeting convened for Wednes¬
day it was intended to propose that the practitioners present
should refuse knowingly to meet in consultation any medical officer
of the above Institution or any medical officer of it who should
subsequently sever himself from the Institution and start practice
independently ; further that they should do their utmost to pre¬
vent those who do meet the medical officers of the Institution from
being called in to consult ; and, lastly, that the present medical
officers of the Three Towns Friendly Societies’ Medical Institution
should be warned of the consequences which would ensue on their
starting independent practice. There is said to be considerable
feeling on this question throughout the profession, and it will be
interesting to learn how the meeting passed off, whilst greater
interest still will attach to the outcome of the pending struggle
between the “medical aid doctors” and the defenders of outraged
professionalism.
The Legality of the P.A.T.A. Methods has been questioned
by some critics, and it is interesting to note, therefore, that, in the
opinion of Sir Edward Clark and Mr. Chas. E. E. Jenkins, none
of those methods are illegal. The main point of the opinion
expressed is that the associated traders would not be liable to be
indicted for conspiracy should they refuse to supply any or all of
their preparations to an individual who was “cutting” some
particular article, either entirely or only at such prices as would
prohibit competition with retail dealers who maintained prices.
Similarly, it is thought that wholesale agents would be justified in
co-operating with manufacturers to carry out such an arrangement
as referred to above, and that a clause in agreements between
manufacturers and wholesale dealers, by which the latter should
bind themselves to pay a penalty on breaking the conditions laid
down, would be legal and valid.
A Catalogue of British Mosses has been published by Mr.
H. N. Dixon, the excellent ‘ Handbook of British Mosses,’ written
by himself and Mr. H. G. Jameson, having already led to a demand
for an index catalogue for the purpose of effecting exchanges with
correspondents and for labelling herbarium specimens, etc. At
the request of numerous correspondents, therefore, Mr. Dixon has
issued a very useful catalogue of species, in which each species is
separately numbered, and each sub-species and variety approxi¬
mately indicated ; also a list for use as labels, the specific name
being separately printed with each variety, and the whole list made of
label diameter, so that it is necessary only to cut off the label in
the form of a slip. Each of these lists is procurable for the small
sum of 6 d. (or the labels, if gummed, 9 d. ). A card with a list of
all the genera, with synonyms, and numbers referring to the
number of the genus in the Handbook is supplied for \\d., or if
on paper, for 1 d. There is no reason, therefore, why British
bryologists should not now put their collections in order with the
names up to date. Some may perhaps regret that Mr. Dixon has
not in all cases adopted the names in Dr. Braithwaite’s classical
work ; though this will present no real difficulty, since Mr. Dixon has
May 1, 1897]
PHARMACEUTICAL JOURNAL.
379
not introduced any new names, but merely retained in such cases
those already well known and largely used. The lists can be
obtained from J. Wheldon, Bookseller, Great Queen Street, W.C.
The Chemists’ Club will hold a dinner at the Holborn
Restaurant, London, on Thursday, May 6, when the chair will be
taken by Mr. Horace Davenport, at 7.30 p.m. Tickets (5s. 6c?. each)
may be obtained of the Honorary Secretary, Mr. W A. Goodall,
2, Farringdon Avenue, E.C., and it is hoped that members will
introduce friends on the occasion.
The Council of the Royal Photographic Society is calling
a meeting of the photographic trade to be held at No. 12, Hanover
Square, A¥., on Tuesday, May 11, at 3.30 p.m., and at which it is
hoped three delegates will be appointed to represent the interests
of manufacturers and dealers on the General Committee of the
International Trade and Technical Exhibition which the Society
proposes to hold at the Crystal Palace next spring. Exhibitors
will incur no risk whatever in connection with this Exhibition,
their liabilities being limited to the charges for floor and wall
space, and no effort will be spared to make the Exhibition a com¬
plete and representative collection fully illustrative of the develop¬
ment and present position of photography, in its widest sense, such
as up to the present has never been held. Any firms of manufac¬
turers or dealers in photographic, photo-mechanical, and kindred
trades who may accidentally have been omitted from the list to
whom circulars are being sent, are requested to communicate with
the Secretary, 12, Hanover Square, London, W.
Popular and Scientific Names for specific substances do not
invariably denote the same thing exactly, the former being fre¬
quently somewhat wider in their scope, and some letters that have
appeared in the Lancet show that this is peculiarly the case with
regard to certain of the internal organs of animals. One writer,
desiring to give thymus gland to a patient who was the subject of
exophthalmic goitre, went to a slaughter-house in order to assure
himself that he would get exactly what he ordered. When he
mentioned “sweetbread,” the butcher said there were three in
the calf — the throat, heart, and stomach sweetbreads, being the
thyroid, thymus, and pancreas respectively, and that the heart
sweetbread was very small in the bullock. This confusion of
totally different organs under the same general term is far from
rare, and medical men or pharmacists who have occasion to pro¬
cure particular glands, etc., usually find it desirable to be present
■when they are being removed. Butchers are gradually becoming
educated with regard to the position of the thyroid, but as yet
there are probably very few who could be depended upon, unaided,
to localise the suprarenal capsules. The medical man referred to
above was informed, by the way, that the testicles make a particu¬
larly tasty dish, and are served under the fanciful name of “moun¬
tain oysters.”
Kites for Meteorology were first used to elevate meteoro¬
logical instruments, recording their indications graphically and
continuously, at Blue Hill Observatory, Mass., according to Mr.
A. L. Rotch, who recently read a paper on the subject before the
Royal Meteorological Society. The date of the initial experiment
was August, 1894, and simultaneous observations were thus
obtained in the upper air and near the ground. The meteorographs
employed of late include an anemothermograph and a barothermo-
hygrograph, both instruments being constructed chiefly of
aluminum, and each weighing less than three pounds. One of
them was hung to the end of a steel pianoforte wire, having a
tensile strength of 280 lbs., between two or more kites, which were
attached to the wire by independent cords. The kites employed
are of several types, such as the Malay kite, which presents a con¬
vex surface to the wind, the Hargrave cellular kite, and a flat kite
with a fin or keel on its front. The meteorographs have been
elevated nearly two hundred times, and valuable data as to the
changes of temperature, humidity, and wind up to an extreme
altitude of 8740 feet above Blue Hill have been obtained. Kites
are held to be greatly superior to captive balloons for meteoro¬
logical observations, except during calm or very light winds. They
are not only cheaper, but they can lift a light load, such as a
meteorograph, touch higher in ordinary winds. Kites have been
used at Blue Hill in all weathers, whenever the wind blew between
twelve and fifty miles an hour, but captive balloons were driven
down by strong winds along an arc whose radius was the lifted cable,
and violent shocks were transmitted to the suspended instruments.
The Proposed Cabot Tower at Bristol, which the citizens of
Bristol have resolved to erect in commemoration of the four
hundredth anniversary of the discovery of the North American
continent, is to be placed on the summit of Brandon Hill, in the
heart of the city, and overlooking the upper reaches of the port
from which, in May, 1497, the “Matthew” sailed on her adven¬
turous voyage. The Bristol Town Council has granted the site on
which the monument is to be erected, and the movement is under
the presidency of the Marquis of Dufferin. The foundation stone
is to be laid on J une 24, the four hundredth anniversary of the day
on which the mainland of North America was first seen by a
European navigator. Contributions may be sent to the Hon.
Secs., Cabot Celebration Committee, Quay Street, Bristol.
Poisoning With Insect Powder, derived from pyre thrum
flowers, is so rare, notwithstanding the widespread domestic use
of the substance, that a case reported by Bosredon ( Bullet . Gen.
de Therap., cxxxii., 275) is of considerable interest. An infant,
aged 11 months, playing with a cardboard box of the powder,
broke the lid, and got the powder into the eyes, mouth, and
nostrils. When medical aid arrived convulsions and vomiting had
set in ; the heart beats were feeble and the respiration slightly
quickened. After carefully removing the adherent powder, an
emetic of ipecacuanha produced free vomiting, and except for slight
inflammation of the conjunctive, the patient quickly recovered.
Louis Pascal Casella, whose death is reported as having
occurred at Highgate last week, had been associated in his time
with many inventions and improvements in scientific instruments,
the most important being the clinical thermometer and the adapta¬
tion of the pressure gauge to the verification of thermometers for
determining the temperature at great depths in the ocean. He
was of Italian parentage, but born in Scotland, and had lived some
seventy years in London. He was a Fellow of the Astronomical,
Geographical, and Meteorological Societies, and his services to
medicine and meteorology were great, whilst many scientific men
found in him a helper and a friend.
The Optical Classes under the charge of Mr. Lionel Laurence,
which have been organised by Messrs. J. Raphael and Co., of 51,
Clerkenwell Road, are being very well attended, so much so that
they have to hold one almost every week. The importance of
knowing how to properly adapt glasses is so great that it is hardly
necessary to dilate upon it, and Messrs. Raphael trust that every
chemist who also deals in optical goods will avail himself of these
classes. Chemists who are not at present interested in the optical
trade may find it greatly to their advantage to take up that fine
of business, and when doing so they will doubtless find it advan¬
tageous to make themselves proficient by taking a course of
instruction with Messrs. Raphael and Co.
380
PHARMACEUTICAL JOURNAL.
[May 1, 1897
THE WORLD Of PHARMACY.
- ♦ - -
BUSINESS MEETINGS.
Midland Chemists’ Assistants’ Association, Wednes¬
day, April 21. — Mr. H. S. Lawton, President, in the chair. — Mr.
F. H. Alcock read an interesting paper on
The Studies of a Pharmacist,
with illustrations from the examination syllabus, in the course of
which he assumed that those he was addressing were familiar with
the ordinary shop training, and therefore specially directed his
remarks to that part of a pharmacist’s training which was con¬
sidered to be the results of their examinations. Referring to the
great necessity of a sound knowledge of botany in the young
pharmacist, he urged that the study of the microscope could be
learnt in the shop, and that a microscope, together with a good
collection of materia medica specimens, should be part of the
stock-in-trade of the pharmacist who took pupils. The British
Pharmacopoeia should be to the young man a very familiar book,
and at the outset of his career his parents should be told that it
was a necessary first expenditure. With the aid of it and a little
assistance from his principal, his qualified assistant and senior
pupil, the beginner should have no difficulty in making a
successful start in the subject. They would not have
what he very frequently saw, and which examiners complained
of so bitterly, the man who could not distinguish between
sassafra and quassia, and similar shortcomings. Mr. Alcock
also similarly dwelt upon the necessity for soundness in the know¬
ledge of chemistry with its branches, including physics and
weights and measures, and pharmacy including such operations as
the preparation of galenicals, the dispensing of physicians’ pre¬
scriptions and family recipes, knowledge of pharmacy law and all
Acts of Parliament and rulings thereon pertaining to their calling.
The paper was extensively and admirably illustrated. — In the
course of the discussion the Chairman said that the paper was a
most valuable one, and a useful indication of the preparation
necessary for an apprentice to make during the time of study.
The Proposed New Bye-Laws.
The Chairman next moved —
“ That this Association expresses its support of the Pharmaceutical Society in
the proposed changes in the bye-laws relating to examinations, and further
expresses the opinion that the Preliminary or First examination, should be
made compulsory before apprenticeship.”
—Mr. Bindloss seconded the motion, and said that he thought
the proposed new First examination would have the important
effect of opening the eyes of the would-be student of pharmacy to
what was expected of him, and he would very soon find out whether
he was adapted to shine in the pharmaceutical world. He
strongly approved of Mr. Alcock’s methods in educating the
student during his apprenticeship, and thought that the
apprentice did not at present get that training from his
master he was entitled to. He, however, thought it was too much
to expect the master to keep a materia medica museum for his
apprentice. — Mr. F. J. Walton was of opinion that the alterations
in the bye-laws were worthy of cordial support. They would
prevent many from entering on a career for which they were totally
unfitted. — The resolution was further supported and unanimously
agreed to. A cordial vote of thanks was accorded Mr. Alcock for
his paper.
Edinburgh Chemists’, Assistants,’ and Apprentices
Association, Friday, April 23. — Mr. James McBain, President,
in the chair. — The annual business meeting was held in the Phar¬
maceutical Society’s House, 36, York Place, Edinburgh. — The
Secretary read the report of the Ewing Pharmacy Prize Compe¬
tition, from which it appeared that five apprentices had competed,
and the Ewing Prize (value £1 Is.) had been gained by Albert
Edward Kelly, 23, Bernard Street, Leith. For the second
prize William Center, 25, Ardmillan Terrace, and Peter
Cowie, 85, Bruntsfield Place, were equal, and as the third
competitor had not sufficient marks to gain a prize, the
Committee had combined Mr. Atkins’ and the President’s
Prize (10s. 6 d. and 7s. 6c2. ) and given two second prizes. —
Mr. J. Laidlaw Ewing, in presenting the prizes, said he had to
congratulate the Association on the successful session they were
now bringing to a close. He had only one fault to find, and that
was that they secured for their meetings some papers which he--
thought should have been read at an evening meeting of the.
Society. There was one point he would like to refer to. They
had just concluded the April examinations, and it was a matter of
sincere regret to the Examiners that so many had failed. It was
one of his most disagreeable duties as Chairman to tell candidates
that they had failed. On the subject of the failures two things-
occurred to him to say. First, as to the more strictly scientific sub¬
jects, he would urge them to begin early to get a knowledge of them, so
that by careful and systematic study they might get a thorough
grasp of first principles. The absence of this thorough knowledge-
was often painfully evident in the examination room. Secondly,,
they should take care to get up fully all the subjects. It frequently
happened that candidates had got up several subjects well, but had
neglected one or two, and that frequently brought them to grief..
Due attention to all the subjects would have led to a happier result.
He then presented Attfield’s ‘ Chemistry,’ Ince’s ‘ Grammar,’ and'
Green’s ‘ Botany,’ vol. i., to A. E. Kelly ; Newth’s ‘ Chemistry ’ and
Muter’s 1 Analytical Chemistry ’ to W. Center ; and Gerrard’s
‘ Materia Medica’ and Green’s ‘ Botany,’ vol. i., to P. Cowie. — On
the motion of the Chairman a hearty vote of thanks was awarded
to Mr. Ewing. — The Secretary then read the Annual Report,
and the Treasurer read the Annual Financial Statement,
which were approved of. From these it appeared that the.
number of members showed a slight decrease, but there was an
increase in the number of apprentice members. The meetings
had all been carried out and were well attended. The Association
having expended the funds available for the Association prizes,
these had been dropped, but it was intimated that Mr. David
McLaren had offered an annual subscription of £2, to allow the
prize scheme to be continued. The financial statement showed a
balance of £6 3s. 8c?.— Mr. David McLaren was elected an honorary-
member. — A discussion then took place on
The Proposed New Bye-Laws
of the Pharmaceutical Society.- — Mr. George Coull, in open¬
ing the discussion, said : In regard to the proposed in¬
crease in the scope of the Preliminary examination you will
not expect to hear any adverse criticism from me. It is exceed¬
ingly gratifying to find that there has been hardly a dissentient-
voice heard concerning this matter ; even the Boanerges of Cannon
Street, while not exactly stamping it with its approval, has treated
it most mercifully. It will, however, be necessary for the Council
to make perfectly plain what certificates are to be accepted and
what are not. There has been some dissatisfaction in Scotland
regarding the non-acceptance of certificates which, in my opinion,
certainly ought to have been received in lieu of the Preliminary.
So far as I have seen, there is a good deal too much of “ the un¬
written law’ in conducting the Society’s affairs. After the bye¬
laws receive the assent of the Privy Council, a list ought to be
published distinctly stating what certificates are to be accepted
and any conditions the Council likes to make ought to be clearly
mentioned. I also urge that any change to be made in
the examination regulations should be fully advertised
instead of being quietly introduced without previous notice,
although the alteration may be underlined or in italics.
The proposal to increase the fee for the qualifying examination has-
not been received with the almost unanimous approval that has
been accorded to the Preliminary examination suggestions. The
objectors, so far as I can make out, may be considered under two
heads : — 1. Those who think they are pecuniarily affected by the
Pharmaceutical Society ; 2. Those who are directly hostile to the
Society. Belonging to the former class are proprietors, editors,
and so on of papers which call themselves rivals to the official
organ of the Society, along with the proprietors and lecturers at
certain Schools of Pharmacy, who style themselves opponents of'
the Society in its educational work. Of the second class are those
who from the tenour of their communications in the trade journals
have an unreasoning antipathy to the Pharmaceutical Society and
all its connections, but the line of demarcation between the two is
very ill-defined, and the two classes insensibly run into one
another. The Chemist and Druggist in striving to get up an
opposition to the proposed bye-laws spoke very feelingly about
the “iniquity” of taking money from candidates to subsidise a,
rival journal. It has often been said that figures can be made to
prove anything ; when it is a choice then between believing the
figures of the editor of the paper in which one has a share and the
editor of a rival paper, we must take the figures of our own official.
In connection with this I would commend to the serious attention
May 1, 1897]
PHARMACEUTICAL JOURNAL.
3RL
of you all the editorial in the Journal for March 20, and also the
leaderette immediately following. I do not imagine that the
opposition is at all pleased at the response to its imploring cry for
all members of the trade, and more especially local pharma¬
ceutical associations, to give this matter serious attention. I may
say I do not appreciate letters signed by all the virtues, such as
“ Prudence,” “Justice,” and “ Veritas.” We have had experience
of that sort of thing in Edinburgh, where it is a well-known fact
that a very important and influential paper used to write letters to
itself signed, “Ratepayer,” “Pro Bono Publico,” “Another
Ratepayer,” and so on. If a man wants any notice to be taken of
his views he should certainly have the courage to sign his name.
Mr. Coull then went on to explain that the deficit on the Journal,
divided by the number of subscribers, was rather more than half
the subscription, andas it was the only tangible thing each one got for
his subscription, it did not matter to anyone although he paid
even more for it than it cost at present. But he was sure that the
present cost — resulting from expenditure incurred in response to
requests from members of the Society — would soon be reduced. He
then moved —
“ That this Association approves of the new bye-laws as proposed by the
Council of the Pharmaceutical Society, and considers that they are desirable,
both in the interest of the public and of those engaged in the business."
— Mr. Lunan seconded the motion. — Mr. Cameron said he would
not move any amendment, but had an impression that £5 5s.
should be enough for the Minor unless there was a sponge some¬
where that sucked up the funds. — Mr. Currie moved as an
amendment —
“ That the Association approves of the extended Preliminary examination, but
disapproves of the proposed increase in the Minor fee.”
Mr. Kidd seconded the amendment. — After an interesting discussion
a vote was taken, when eight voted for the amendment and twelve
for the motion, which was declared carried. Several did not vote.
Election op Officers.
The following office-bearers were elected for next session : — •
President, George Sinclair ; Vice-President, J. Donald Sinclair ;
Secretary, G. H. C. Rowland, 117, Princes Street ; Assistant-
Secretary, David Harley ; Treasurer, J. L. Reid ; and as members
of Committee, Messrs. Cameron, Center, Currie, Kidd, McBain,
Mowat, Sivewright, and Sutherland ; as members of Prize Com¬
mittee, Messrs. Cameron, Dey, and McBain.
Newcastle-upon-Tyne and District Chemists’ Asso¬
ciation, Wednesday, April 28. — Mr. T. Maltby Clague, Presi¬
dent, in the chair. — After thanking the members for his election as
President, Mr. Clague proceeded to deliver the following inaugural
address on —
The Part of Combination in Modern Pharmaceutical Life.
Combination is not only the order of our day, but it has been the
order of ages that are past. We have lived through the period of
commercial history which has seen the decay and death (though
perhaps hot the reverent burial) of the old trade guilds, and
we have lived into the age when trade unionism has become a
factor which none can afford to ignore ; and this in turn
necessarily met by combinations amongst capitalists and em¬
ployers to safeguard their interests. In itself combination is
neither good nor bad. That trade unions have done good none of
us will deny. That they have never done harm none dare affirm.
That syndicates have kept alive a decaying industry which other¬
wise might have been ruined — that they have opened out fields
too vast for individual enterprise is a safe predication ; but
who that stands outside can help execrating the monopolist
syndicate controlling some of the necessaries of life in America
at the present moment ? And so when we take in hand
our subject of combination for the modern chemist we
must be content to judge its founders by the nobility of its
purpose, by the discretion displayed in their operations, and
the beneficent character of the results obtained. I venture to lay
before you this proposition, gentlemen — that we individually owe
a great deal to combination and to the wisdom of our predecessors,
who combined so well and used their Society with such good effect.
I refer particularly to the founders and carriers-on of the Pharma¬
ceutical Society. The chemist has become differentiated from the
rocer, herbalist, and botanic beer-maker, and examinations have
een placed before him which have enabled him to prove
his capacity for the life work which he has set himself,
and have given him credentials to show the world
that he has that capacity. And such was the volun¬
tary work of the Pharmaceutical Society, unaided by the
State. The Act of 1868 was a fusion of the nation’s interests and
ours — to protect the public was sought by Parliament and the
protection of the chemist was also sought. Many of us think that
a little more protection would not have harmed either of
the parties to the contract. Henceforward the qualifications of
the Pharmaceutical Society should have been a necessity to every¬
one who engaged in keeping open shop. That such was the
intention of the Legislature there is no doubt ; that the safety of
the public requires it is equally beyond dispute. But loopholes
have been found, and the law has been evaded in instances beyond
count. Now, however, I am urging that the Pharmaceutical
Society did a good thing for us in providing qualifications
for us to get and to hold, and am met at the outset by the objec¬
tion that if some can get on without the legal status there is no
value in it. “ What is the use of getting qualified ? ” I have heard
over and over again, and from the man who utters it I turn with
admiration to a picture in fable-lore which tells of a certain vulpine
quadruped who asserted that the grapes so “ ungettatably ” placed
above his head owed their fulness to acid juices rather than to sac¬
charine. One can’t always turn away from the man thus ;
perhaps the train has started and won’t stop for twenty miles,
and we are imprisoned vis-a-vis with our tormentor, and
so one is compelled to state his reasons for believing
that the qualification is of importance. Here are mine : —
Because those who have not got it and are engaged in illegal
trading want it ; and whenever their early education has been
good enough for the Preliminary, and they have brains and energy
enough for the Minor, they go for both. Next, because the public
—in spite of its unwise running after cheap ! cheap ! — does set
some store by qualification ; and third and most important reason,
because I am a self-respecting man and owe it to myself as well as
to the community that I come up to the established standard of
knowledge in the profession which I practise. And for these reasons
I frankly acknowledge that the Pharmaceutical Society has done a
good work. In considering this combination (the Pharmaceutical
Society) I have not claimed, and I do not claim, that all has been
done which was possible, but I do hold that the main reason for
failure to accomplish more has always been the meagreness of the
support given to it by the trade generally, many of whom once
having got its licence or ticket have never in any way helped
forward the Society, or, to put it more in the terms of my address,
have not combined with their brethren for the common good. It
might be too daring a thing for a matter-of-fact man like myself
to attempt, but why should not an imaginative member of this
Association give us a paper on “ What an Ideal Pharmaceutical
Society Supported by an Entire and Loyal Trade might have
Done.” Before dismissing from review the subject of the Pharma¬
ceutical Society as a combination, let me point out, that by its
high claims and aims for pharmacy, by its incorporation of so
many men of real power and merit ; it has forged its way to its
present position, a position commanding respect from all scientific
and philosophical institutions and from the Government of our
country, as witness the compiling of a new Pharmacopoeia, for
whilst not wishing to detract from the kindness of those who have
asked the co-operation of the Pharmaceutical Society in this matter,
I venture to say that had such help not been invited we might
have demanded, and public opinion would have given, a partnership
in that work. Judged, then, by the aim which it set before itself, by
the way in which it has worked in the main, and by the results
achieved, we must admit that it is well for us that there has
been such a combination as the Pharmaceutical Society of Great
Britain. It would have been very interesting to have gone a little
into the history of the old Chemists and Druggists’ Association,
and the causes of its decease ; but time forbids, and I pass on to
consider another form of combination amongst chemists represented
in our thought to-day by the P.A.T.A. The existence of the
defunct association to which I have just referred and the recent
birth of the healthy young infant association are proofs of the
statement that there are matters quite outside the sphere of the
Pharmaceutical Society’s work which are legitimate objects
for combination in our craft. While we hold the view that
it would be unwise for the Pharmaceutical Society to take
up matters which are purely matters of £ s. d. , we at
the same time claim our right and acknowledge our duty to see to
it that we get a fair remuneration from the community for
the capital in cash and in brains which we place at its service.
And if in the arrangement of our affairs it becomes necessary to
see to it that a few self-seeking, greedy extreme-cutters are not
382
PHARMACEUTICAL JOURNAL.
[May 1, 1897
able to inflict injury on others as well as on themselves, we are
justified in using any lawful means to that end. And the word
lawful I use to signify means that not only are struck at by no legal
enactment, but means that are ethically justifiable. Now let us
consider the case of proprietary articles. Here the ordinary com¬
petition is interfered with and the business tends to become one-sided
in its working. Mr. Retailer can only obtain his supplies of Mr.
Proprietor’s Curall from Mr. Proprietor himself, and yet he is
subject to competition from Mr. Retailer Secundus in that article.
Further, two things are admittedly essential to the successful sale
of the Curall- — Mr. Proprietor’s advertising and Mr. Retailer’s dis¬
tributing ; it is most generally admitted that in cases of this
description intrinsic merit in the Curall is quite unnecessary. The
advertising is secured by the self-interest of Mr. Proprietor ; the
distributing is only secured by the mutual bargain between the
two men. Here, then, obviously is the bargaining ground for the
two interests concerned, and it would be well to recognise at once
the limits of this field of operation. What profit does
Mr. P. offer to us, and how is that profit secured to
us ? History warns us on this point. The “ patent ”
medicine proprietor of the past used the chemist to create
the distributing trade, and when the cutter came in and
took the profit from us, showed precious little sympathy and gave
less help. History may repeat itself. Indications are not wanting
that it will repeat itself as far as our loss is concerned, the prob¬
able difference being that this time it will be the proprietors who
will try to get all the profit. The mode of working is that the
wholesale price is gradually worked up nearer and nearer to the
face value, and our margin is narrowed till it is scarcely visible
and never palpable. By what action can we meet this effectively ?
I know of none which the individual can practise successfully. Few,
very few, are the businesses in which it would be wise to refuse
to sell any of the articles for which our customers ask, and those
retailers who dare do so are men whose trade is not worth the
proprietor’s consideration. But if we have a strong association of
retailers it is conceivable, indeed, probable, that the strongest
proprietor may be brought to fair terms, and as far as I can see it
is only by such combination that we can hope to act with effect.
Every additional member will add to the striking power of such
an association, and in helping forward by numbers and influence
such a movement we are doing what seems to me best for
ourselves in our present circumstances. And as to modes of
working, it is both reasonable and right to refuse to do work
which we are not paid for doing, and to sell that which we
are not paid for selling, and when we fully represent
the sellers we are justified in asking Mr. Proprietor to secure to us
a reasonable profit on the handling of his article, or in modern
parlance, prefer our demand: “Protect this article.” There has
been put forward in certain quarters a suggestion that not only
should this be done, but a general boycott be entered into against
firms who own proprietary articles in their general trade in drugs,
etc. This strikes me as going beyond the right, and not playing
the fair game. And now to come to our own Society, the New¬
castle and District Chemists’ Association. What may we reason¬
ably hope for from this combination ? I believe we may look for
several advantages. First, there are opportunities such as that
which I enjoy at the present moment of urging on one’s
neighbour the claims of the larger and national organisations. Wher¬
ever local associations are healthy there the Pharmaceutical
Society has a good hold, and there also the P.A.T.A. has had a
better opportunity of securing adherents. Again, there may
often arise openings for local co-operation for the good of the local
craftsmen. Added to these is the great advantage of personal
knowledge of each other, the clearing up of misunderstandings,
and the removal of those petty jealousies which have done
so much harm in the past. I claim this much for combina¬
tions amongst pharmacists, and if I have been too
moderate in my claims, my reason for such moderation is
that I see no wisdom in hoping for good where there is no reason¬
able prospect of its coming. Combination will not bring Utopia.
Combination will not make the lazy man a successful one, com¬
bination will not replace individual effort. There are those who
look to anything rather than to personal diligence for their
success, and they will now say, “ We have Carteighe and Hills for
our fathers and Glyn- Jones for our foster-mother, then toil we not,
neither do we spin, but fold our hands and wait.” They will
allow this or that branch of their business to slip past them ; they
will neglect their dispensing “ because there is so little of it in this
place,” and forget the loss of prestige which their neglect entails ;
neglect their science because it is not ready cash ; neglect their Jour¬
nal because it contains some things that are too wonderful for them ;■
neglect their Chemist and Druggist because its friendly help for a
week or two does not happen to be along what they consider their “own
line.” Each of these used fitly would have better equipped them
for the work they have to do and raised them, and consequently
raised pharmacy in the estimation of the public. Ever and anon
there are chances occurring of adding new branches of business,
and these require what our Yankee friends call “live men,” men
who have kept up and worked up their vitality and virility, and
are able to grasp what is worth the grasp. My belief is that some
of the new acreage which opening fields have to offer will be first
and best occupied by that human organism trained in
business and trained in science whom we call the pharma¬
cist. True, it undoubtedly is, that many such workers do
not meet with the pecuniary reward which they deserve ; but
£ s. d. is not the sumnum bonum —the extent of our happiness
has other gauges than the banker’s pass-book, money-making
is not the whole duty and privilege of cultured manhood. My
plea is that it is best for the community in which we live that we
should equip ourselves thoroughly for our work, and best for
ourselves that we serve our generation well.
Forfarshire District Chemists’ Association, Wednes¬
day, April 28.— Mr. Charles Kerb in the chair. — This was the first
meeting of the Association, and amongst those present were Baillies
Doig and Ferrier, and Messrs. J. Russell Anderson, J. Anderson,
Gray, Doig, J. W. Russell, Duncan, Lindsay, Thomson, Park
(Dundee), Laidlaw Ewing, Bowman, Rutherford Hill (Edinburgh),
Currie (Glasgow), Jack and Robertson (Arbroath), Da vi Ison
(Montrose), Kermath (St. Andrews), Fisher (Dunfermline), Peebles
(Lochee), Harley (Perth), Fleming and Skinner (Broughty Ferry).
The constitution and rules were read by Mr. Russell and
approved, after which Mr. Charles Kerr was unanimously elected
President, and he thanked the members for the honour. — Baillie
Doig was unanimously elected Vice-President, and said he
had all along taken a deep interest in the welfare of the
pharmacists of Dundee. This Association would be helpful,
and would rub off the corners and promote good feeling by
their coming together. He hoped it might also help to mould the
educational policy of the Pharmaceutical Society. He rejoiced to
see that Mr. Currie had made a proposal which gave hope that all
pharmacists would become united into one great living organi¬
sation. He was glad that things were tending in that direction.
He hoped they might also do something for the younger men by
formulating a scheme of classes giving opportunity of getting
knowledge fitted for their calling. — Mr. James Russell was elected
Hon. Secretary and Treasurer. — The following were also elected on
the Committee : Baillie Ferrier, Messrs. J. M. Hardie, A. B. Anderson,
William Cummings, J. W. Russell, Wm. Park, O'. Jack (Arbroath),
A. Davidson (Montrose), J. Ford (Kirremuir), G. H. Fowler (For¬
far), Walter Ferrier (Brechin), and W. R. Kermath (St. Andrews).
Honorary Members : Messrs. D. Storrar, J. Johnston (Members of
Council of the Pharmaceutical Society), James L. Ewing, J.
Rutherford Hill, Frank W. Young, W. L. Currie, J. Bowman,
and J. H. Fisher. — A discussion on the proposed new bye-laws at
the Pharmaceutical Society then took place. The extended
Preliminary was unanimously approved. — Messrs. Lindsay and
J. W. Russell moved disapproval of the increased Minor fee
and Messrs. Jack and i Thomson moved approval. — On a vote
being taken, fourteen voted for approval and ten for disapproval.
The Association therefore approved of the proposed new bye-laws
of the Pharmaceutical Society.
Annual Dinner.
The annual dinner of this Association was subsequently held in
the Queen’s Hotel, Dundee, Mr. Charles Kerr, President, in the
chair. Amongst those present were : — Baillie Doig, Vice-President,
and Messrs. J. Laidlaw Ewing, W. L. Currie, J. Bowman,
and Rutherford Hill. — An excellent dinner was partaken of, and
after the loyal toasts, Mr. James Jack proposed the Pharmaceuti¬
cal Society. — Mr. Ewing, in reply, said the Society was founded
by far-seeing and unselfish men, and the Council to-day worthily
followed their example. He now took the opportunity to
explain his view of
The Proposed New Bye-Laws,
which he approved as desirable and essential for the proper
working of the Society. The Minor graduate had now an
important position, and ten guineas was not an exorbitant
May 1, 1897]
PHARMACEUTICAL JOURNAL.
383
sum. In the Edinburgh buildings the Society had done much
for the pharmacists of Scotland ; round them the whole life
of Scottish pharmacy might be said to circle. The expense
of the Journal had been due to improvements urged by Scottish
pharmacists, and should not be grudged. He now strongly
urged that all registered men should be eligible for full member¬
ship and a place on the Council, and that would probably be
done. He commended to cordial support the Benevolent
Fund in the Queen’s Jubilee Year ; Scotland gave the greatest
support to this Fund. — Mr. Rutherford Hill, who took
Mr. Storrar’s place, proposed the Forfarshire Association. —
Mr. Kerr, in reply, said : We are met to-night to inaugurate a
movement for the extension of the Dundee Chemists’ Association
into a larger body, embracing the county of Forfar and district.
This has been a much desired object for a long time, old associa¬
tions get lazy and indifferent, and require to be renewed by new
blood. We have to confess it is difficult to get this new blood.
Why chemists are so suspiciously shy of any movement that is
ostensibly for their good beats one’s comprehension. But for a
first attempt in this extension we have reason to be thankful. We
have received some replies to the effect that if the parties were in
Dundee they would be sure to join, and wished us every success,
but being so .far from the centre, they failed to see what good it
could do them. Now this is just the argument we have to contend
with in trying to get an increase of
Subscribers to the Pharmaceutical Society.
We cannot promise immediate good that any member, person¬
ally, may derive from his 2 s. 6 d. subscription. But if he will give
the influence of his name on the roll of members, that will
always be a power for good. Any cause which would be carried
to a successful issue nowadays must be backed by majorities, and
it is that we want if any good is to be done in forwarding move¬
ments to benefit the whole body. There is another point which,
we fear, has deterred others from joining, viz., a feeling amongst
the brethren of the trade that this Association is formed for the
purpose of an inquisitorial court, to interfere with the freedom of
members in the conducting of their businesses. They are under a
wrong impression. The Association will be worked on constitu¬
tional lines, and every member can have a voice in all its actions.
They can change the office-bearers every year if they like. We
have a broader idea of the working of an association of this kind
than petty interference with anyone’s mode of conducting business.
All the work it does we hope will be for the general good, raising
the whole tone of business, and endeavouring to get everyone to
.act in a brotherly way to each other, and there is nothing like the
-social element in gatherings like this, to produce good feeling, and
when we dine annually, wherever it may be, we hope it will prove
a bond of good-fellowship that none can resist. — Mr. Doig pro¬
posed “ The North British Branch and Examiners.” — Mr. David¬
son (Montrose) replied, and Mr. J. R. Hill proposed “The
Federation Associations.” — Mr. Currie, President, replied.— Mr.
Kermath then proposed “ The Universities,” to which Mr. Young
replied. — Mr. Fisher proposed “The Chairman.” — Baillie Ferrier
proposed “The Croupier.” Apologies were read from Messrs.
Storrar, who was suffering from a severe cold, J. Hardie Johnston
(Aberdeen), Ford (Kirriemuir), Fowler (Forfar). Congratulatory
telegrams were received from Messrs. Johnston and Strachan
(Aberdeen) and P. MacEwan (London). Songs and recitations w^ere
given by Messrs. Currie, Russell, Skinner, Young, and Kerr.
Liverpool Chemists’ Association, Wednesday, April 28.
—Mr. A. C. Abraham, President, in the chair. — A paper w'as read
fey Mr. Wyatt, entitled —
More Dispensing Notes,
which pressure on space obliges us to defer publishing. After a
brief discussion, Dr. Symes addressed the meeting with reference
to the proposed alteration in
The Pharmaceutical Society’s Bye-Laws,
pointing out that by the alteration with regard to the
Preliminary examination, which has met with unanimous
approval, the Society would not in future receive the so-called
“plucking” fees, and consequently there would be a loss
-of revenue. The proposal to increase the fee for qualification
and registration— also very generally approved — was calculated
to benefit the whole trade, not so much by preventing
persons from entering the business as by making them
value the qualification when they got it. The Society’s work
has always been very largely of a public character, even before it
wras officially recognised, but even since the passing of the Phar¬
macy Act in 1868, the revenue derived from the administra¬
tion of the Act has been inadequate to defray the attendant
expenses, and the deficiency has been met by drawing largely
upon the subscriptions from members and associates.
Passing to the statements which have been made as to the cost of
the Pharmaceutical Journal being the reason for increasing the
qualification fee, Dr. Symes showed that there is not the slightest
foundation for them, inasmuch as the published accounts prove
that the Journal has always been a source of considerable revenue,
and the cost over and above that has been defrayed out of sub¬
scriptions of members, associates, and students, with a result
very considerable to their advantage, individually and collectively.
— In conclusion, Dr. Symes referred to a recent attempt to confuse
the subject by introducing an assumption that the stringency of
the qualifying examination is to be increased, and added
that this was a matter of which he, as a Member
of Council, had no knowledge whatever. — The President, in
opening the discussion, said that he personally supported the action
of the Pharmaceutical Society, and hoped to see a resolution passed
by the meeting fully endorsing its action. Members of the
entire trade had received protection for years at the hands of the
Society against illegal traders, and the cost of the various
prosecutions instituted had not been by any means covered by the
penalties recovered, this being particularly the case in Scotland,
where the prosecutions had entailed a heavy loss. The J ournal as
at present conducted was worked at a profit, for by Dr. Symes’
showing it only cost the members about 8 s. per head. The only
thing he had to say with regard to increasing the difficulty of
entering the profession was that this very difficulty might encour¬
age outsiders to poach upon their preserves. He would like to see
the Society go still further, and try and retain to the qualified
pharmacist the sole right and privilege of dispensing medical pre¬
scriptions. The future financial state of the Society would be better,
for the cost of the Journal — improperly looked upon now as a loss
— is becoming gradually reduced. The improved state of affairs
when the cost became further reduced would enable the Society to
extend its already large sphere of usefulness. — Mr. Cowley said that
to an outsider the giving up of the Preliminary might be regarded
as a sprat to catch a whale. The term “administrative expenses”
seemed to him to cover a very extensive field, but no doubt the
expenditure in the past had been carefully considered and was
justified. He did not look upon the introduction of the professorial
element on the examination board as by any means satisfactory, for
professors were just as likely to run in grooves as any other class of
men, in fact more so, and it sometimes seemed as if the desire to
“pluck” was more evident than the wish to find out what a candidate
knew, still in the main he personally supported the Society, and from a
selfish point of view he regarded the increased fee with equanimity,
for he felt assured it would deter the students from having- “ shots ”
at the examinations, and they would only go up when well pre¬
pared. — Mr. J. Smith was satisfied with the clear exposition of
the case for and against the alterations as stated by Dr. Symes,
and agreed that the deterrent effect of the increased fee could
only be beneficial to improperly prepared students and indirectly
to the Society, for such students, after repeated failure, were apt to
become thoroughly disgusted with the examinations and the
Society, and to regard it in the light of an enemy. — Messrs.
Marsden and Wyatt also supported Dr. Symes, as did
Mr. Mitchell, who confessed that since the alteration in the
proposed bye-laws made at the last Council meeting, he could not
see any objection to the change, though he would like to see a
little time of grace allowed to those apprentices who had entered
the business during the time the present bye-laws were in force.
—After a reply on the part of Dr. Symes, during the course of
which he said he hoped to see the present method of allowing so
much time to elapse between the first and second days of the
examinations considerably altered, to the pecuniary benefit of the
students, the President moved a resolution worded as follows : —
“ That this meeting is desirous of supporting the action of the Pharmaceutical
Society in proposing an increase in the fees for the qualifying examination,
and thereby ensuring that those who live under the protection of the Society
shall contribute towards the expenses incurred by it, rather than that such
expenses should only fall, op now, upon those who subsequently join the
Society as members or associates.”
— Mr. J. Smith seconded this resolution which, on being put to the
meeting, was carried unanimously.
384
PHARMACEUTICAL JOURNAL,
[May 1, 1897.
EXTRACTS FROM CONSULAR REPORTS-
The Imports op Chemicals into Italy during the year 1895-96,
as compared with the previous year, decreased by 1255 tons. The
total imports amounted to 1445 tons, of which 1140 tons, consisting
of oxides, acids, alkali, and sulphates were imported from Great
Britain. The native production of these articles increases every
year, the consumption of Italian manufacture during the year
amounting to 513 tons.
Drugs and Chemicals imported into Spain during 1896, ac¬
cording to the report of SirH. Drummond- Wolff, decreased in value
1,250,000 pesetas (£50,000).
The Quicksilver Mines at Almuden were considerably ex¬
tended during the year, the amount of mineral extracted being
22,100 tons. The mines elsewhere also showed satisfactory results,
the total amount of quicksilver obtained being estimated at 43,884
flasks (frascos). In the same report attention is called to the
diminished imports of petroleum, which is stated to be due to the
development of electric lighting and to the considerable consump¬
tion of alkaline carbonates and nitrate of soda, which it is hoped
will stimulate great chemical industries in Spain, all the primary
material being ready to hand.
Arsenical Water to the extent of about 20,000 bottles is
reported by Consul-General Freeman to have been exported from
the springs of Guber, near Vlasenica, during last year.
Botanical Work in Jamaica. — The Governor’s Report on the
Blue Book of the Colony of Jamaica for the year ending March 31,
1896, furnishes an interesting account of the work done by the
Botanical Department. The increased interest which is being
taken in agriculture and the growing desire to improve the quality
of the island’s products has greatly increased the demand for in¬
struction and for plants. The services of the Superintendent of
the Hope Gardens for lectures on cultivation with practical illus¬
trations being more and more in demand in the country districts,
an outcome of which it is hoped will be the adding to the income of
the island much of the large sums that are now annually lost by
reason of the unintelligent methods of cultivation adopted and the
imperfect curing of the crops. Good work is also being done at
the Hope Gardens in training boys as gardeners and agriculturists.
A Similar Botanical Station was established by the Government
at Aburi on the Gold Coast, in 1890, which has been the means of
inducing the natives to interest themselves in the cultivation of
coffee, etc. , but the system of apprenticing natives to the botanical
station for instruction in agriculture has not been a success, so a
change is to be made, and it is proposed to select a certain number
of natives of education (a competitive examination will beheld, the
standard being standard vi. of the elementary schools) who will
be trained for one year under the curator of the Botanical Station
in the Gold Coast, then for one year in the Botanical Station at
J amaica, and finally for one year in the Royal Gardens, Kew. The
lads thus selected and trained will be required to apprentice
themselves to the Government for a definite period, and will be
employed in disseminating a proper knowledge of cultivating
products o f economic value among the natives, and stimulating
them to apply themselves to an industry which will be of benefit
to themselves as well as to their country.
Chinese Opium. — Writing from Shanghai, respecting the
revenue and expenditure of the Chinese Empire, Sir N. J. Hannen
states that the returns of duty and likin levied on native opium
are manifestly understated, the estimated sum total realised from
this branch of revenue being 2,229,000 taels (£371,500), a sum
which he thinks is ludicrously small, seeing that the total produc¬
tion of opium in south-western China sixteen years ago was
estimated at 224,000 piculs (of 133)4 Its.), and the cultivation has
certainly not decreased since. If the opium were taxed in the
same proportion ad valorem, as foreign opium (60 taels per picul),
a gross revenue of 13,000,000 taels should be received from this
part of China alone, instead of only 1,000,000 taels which is at
resent returned from these provinces. The total revenue drawn
y China from foreign opium is over 6,000,000 taels, and the
revenue from native-grown opium ought, with equal taxation,
value for value, to yield from 15,000,000 taels to 18,000,000 taels.
LETTERS TO THE EDITOR.
The Proposed New Bye-Laws.
Sir, — As chemists’ associations in different parts of the country
are discussing the proposed new bye-laws and we have no such
association, I have ventured with your permission to discuss them
through the columns of the Journal. As a new Council is shortly
to be elected, I think we ought to get from the gentlemen aspiring
to the honour some sort of an election address, putting before the
electors their views as to pharmaceutical politics and giving an
idea of the measures they would be prepared to bring forward or
to adopt if brought forward. Up to the present, as -far as I can
see, the majority of the associations have declared in favour of the
Society’s action as proposed by the new bye-laws. But I do not-
find the opinions of the minority represented. Being one of
the minority I dissent on account of the increased fees for the
Minor doing no more for the men who have passed than does the
five-guinea fee now or even the three-guinea fee when I passed. I
take it from the fifth section of the Pharmacy Act last clause,
“ the person registered shall pay the same fee as persons admitted
to the Register after examination under this Act,” means that no
one’s name should be upon the Register who fails to pay the
annual subscription, which I take is the fee for registration. This
is a point I tried to get Mr. Carteighe to see at the Conference
held at Plymouth, October 16, 1895.
After registration what does the Society do for those who are
registered ? Did they take any action on behalf of those perse¬
cuted for the sale of milk of sulphur, citrate of magnesia, and are
they taking any action for those prosecuted for selling limes and
glycerin to-day ? To my mind these senseless prosecutions with¬
out any aid to defence from the Pharmaceutical Society has caused
many defections on the part of Members and Associates in the
past, and what of the future ? Is an increased examination and
registration fee to be the panacea for the ills we endure ? Is this
the way to break down the evils of company trading and other
illegalities ? I trow not. Unless licences be given to qualified
men, and the conduct of their business be controlled by the
Society as the governing body, I fail to see what we have
to hope for if the proposed new bye-laws get official sanction.
By control in the conduct of their business by the Society I mean
that the local secretary of each division be empowered to see that
every man who keeps an assistant keeps one qualified to conduct
the business in his absence. All assistants to be granted a licence
to show his official recognition by the Society, and in case of his
leaving a situation, his new address be furnished the Society to
amend the Register. This would prevent any such complaint as
your correspondent, Mr. C. J. Rees had to make a short time
since, re Impersonation. I would dwell further upon the subject,
but will content myself with what I have said for the present,
leaving the questions of higher education, etc., for another letter.
Torquay, April 26, 1897. W. J. Rawling.
Chouan Seed and Autour Bark.
Sir, — In the ‘ Painter’s and Colourman’s Complete Guide,’ by
M. Tingry, published at Geneva in 1830, the following passage
occurs at page 113 : —
“A mixture of 36 grains of chouan seed, IS grains of autour bark, and as much
alum, thrown into a decoction of 6 gros of pulverised cochineal and 5 pounds
of water, gives at the end of 6 or 10 days a red fecula, which, when dried,
weighs from 40 to 48 grains. This fecula is carmine.”
Can any reader of the Journal say what substances are meant by
“chouan seed” and “autour bark,” and also what quantity
“ 6 gros of pulverised cochineal ” is equal to ?
April 24, 1897. Pharmacist (90/11).
Sweating the Dispenser.
Sir, — I should like, with your permission, to reply to “Dis¬
penser ” (p. 305) on the above subject, as I regret to see he has
come to hasty conclusions about the qualification of the dispenser
mentioned in my former letters. I said he held none of the quali¬
fications mentioned by “ Dispenser,” although he holds one that is
accepted by the Local Government Board, and one that can be got-
without an apprenticeship, hence my desire to see none but regis¬
tered persons holding these posts. On this point I should like to-
refer him to an annotation in the Pharmaceutical Journal, p. 319,
“The Qualification of Unregistered Assistants,” which puts the
matter in the clearest possible light. Dispensers in these insti-
May 1, 1897]
PHARMACEUTICAL JOURNAL.
385
tutions, I admit, do not sell poisons, but they have a sufficient
quantity of alkaloids and poisonous extracts in their care to kill
all the patients dispensed for, and if they put up from 300 to 500
bottles a day like a beer bottler working on piece work, it seems
to me there is great danger of there being “death in the pot.”
The case referred to, he says, is an isolated one. I wish I could
endorse his statement. Perhaps he can tell us how many of the
118 dispensers employed in the Poor Law service are registered
chemists and druggists ? I do not wish him to give up dispensing,
but to cease doing two men's work, or it will certainly bring him
to an untimely end.
There has been during the last twenty-five years a great advance
in every department of the Poor Law service, with the exception
of the dispenser, and I think they may profitably consider whose
fault it is that they have gone back to a date anterior to 1871. The
medical staff has improved in qualification and remuneration. The
nursing staff also, none but trained nurses being employed, Mrs.
Gamp and her friend. Mrs. Harris are quite superseded. The
clerical staff has been very much increased in number, with a
corresponding increase in remuneration, some assistants getting
£200 per annum. The relieving officer is now quite a gentleman
with £180 per annum. Why has the dispenser been left behind
with £140 maximum, is it any fault of his own, does he make him¬
self too cheap and treat his office with less importance than it
deserves ? If guardians say a dispenser can do five hundred pre¬
scriptions a day, they must have some reason for it. Let dispensers
wake up and see they are not put on a level with the store
keeper who gives out the food, etc. In reply to your
correspondent “ Blad R. O’Lard,” page 263, I think it
is only by looking straight at how the work is done
that there is likely to be any improvement in it. I consider it
absolutely necessary that every person who dispenses poisons
should be trained and registered. The linseed meal, ointment, and
pills ought not to be doled out — as he says they are — in coal-bags,
saucers, paper, etc. His linseed meal should be put into grease-
.proof bags, his ointment and pills in boxes, which can be bought
at a small cost and labelled in a proper manner. It does not
matter about the kind of bottle used, provided it is clean. Surely
his Committee would agree to this if it were properly placed before
them, and do away with such a bad state of things as he mentions.
What would be the effect of poulticing a wound with meal from a
coal-bag, or dressing one with ointment from a dusty saucer ? The
letter of “A. P. S.” (page 285) I endorse, except where he says the
Local Boards are not responsible, for they have power to select the
best men, and if the registered man is falling out it is that they
select the others to fill his post. The Local Government Board do
not say they must employ unregistered men, but that they may,
and it is clearly their fault if they do.
April 13, 1897. Anti-Sweater (89/35).
Preserving the Colour op Alga:.
Sir, — In connection with your natural history note on Lathrea
squamaria, I may mention that I have found the oxalic acid method
very successful for the preservation of the colour of certain algse
belonging to the Rhodophyceae. Among others, Galliblepharis
ciliata, which, if dried in the ordinary way, becomes quite black,
will retain its bright red colour if dried between bibulous paper
previously soaked in solution of oxalic acid. I have not tried the
method with land plants.
Gosport, April 21+, 1897. Harry H. Sturch.
Difficulty, in Dispensing Cocaine.
Sir,-— In the drops which F. W. D. (88/25) has found difficult to
dispense — cocainse hydrochlor. , /d- ; boracis, gr. x. ; vinum opii,
ui xx. ; aqua, ad. fii. — the difficulty may be overcome by adding,
say, six grains of acid boracic. This would prevent the cocaine
precipitating.
Portmadoc, April 20, 1897. T. Jenkins.
Chemists’ Holidays.
Sir, — May I make a suggestion through the columns of our
increasingly interesting and useful Journal ? It seems to
me there are at least a limited number of small country
chemists who can only rarely afford to get a qualified “locum”
and go away for a good holiday. Some of these in none too
good health. Now, here I am in a village near the north-east
•coast, in a pleasant healthy village, but am wanting to try the
effect of a change somewhere south or south-west for a month or
two. I conceive it probable that there may be some other chemist
who would not object to a change north for a time, living in just
such a place. If such cases do occur, could some exchange bureau
be arranged for such, either through the Journal “ Exchange” or
the ordinary advertising columns ? In such an exchange it would
be to the interest of each to do his best for the other. If married,
and the home or part of house was exchanged, the wife and family,
if they went, might derive the full benefit of the change, and the
chemist, even though on duty, would derive part of the benefit,
besides such advantages as might accrue to him from seeing the
working of another business, and I think we can all learn some¬
thing from each other in a business covering such varied ground
as ours ; and when one has settled down in business, particularly a
small country one, our chances of coming into contact with other
ways are not too plentiful. I should be glad to hear from anyone
who considered the scheme at all a practical one. I think it is
rarely that any objection as to learning each other’s secrets could
occur, for few chemists’ businesses are in any way related to others
more than fifty miles away.
April 20, 1897. A.P.S. (91/15).
* * The “ Exchange ” seems to pi-ovide for the case here raised, and the best way
* of testing the practicability of the scheme will he for A.P.S. to utilise it for
the desired purpose. — [Ed. Ph. J.]
“Potato Drops” and “Green Mallet.”
Sir, — In your reply to Lyra (page 346) you say you do not
know “ Potato Drops.” During my apprenticeship in the sixties,
an old gentleman used to come for what he called “ electer potato-
popis,” when we gave him tinct. aloes co. as representing the old
elixir proprietatis dulce. “ Green /Mallet ” I take to be emplast.
de meliloto, commonly called green melody, but now rarely asked.
for, I imagine. T r. w
Teignmouth, April 16, 1897. J • J • 0* Evans.
London v. Country Members of Council.
Sir, — I am sorry to hear that my respected friend Mr. Gostling
retires from the Council, but I cannot agree with his views as
regards the desirability of electing London men in preference to
country men. We do not want subservient followers on the
Council, but men of independent judgment who. have had some
experience in public business. The question of distance is a small
one, as a Cambridge representative could be on the spot when
wanted almost as quickly as a London man (suburban). Although
not personally acquainted with the Cambridge candidate (Mr.
Campkin) he certainly strikes me as far and away the ablest man.
He is a Justice of the Peace for the borough, a Past Grand Master
and a Director of the Manchester Unity of Oddfellows, a Guardian
of the Poor and Chairman of the Assessment Committee, a member
of Town Council, etc., etc. This gentleman appears to me to be
acquainted with administrative business, and would, in my judg¬
ment, be a welcome addition to the Council Chamber.
Norfolkensis (92/12).
An Assistant’s Qualification Wanted.
Sir, — Judging from the letter of your correspondent of last
week, Mr. F. R. Bessant, one cannot help coming to the con¬
clusion that his experience of “qualified ” assistants cannot have
extended over any lengthened period or he would scarcely adopt
the tone he did. Everyone of course admits that examinations are
not a perfect method of testing anyone’s ability, but nobody seems
able to propose a more efficient substitute. Doubtless a few get
through who hardly deserve to do so ; but, taking the average
qualified assistant, he is, as far as my experience shows, superior
as regards knowledge of business and skill in dispensing, etc., to
the unqualified man of the same age. Is it possible that Mr.
Bessant fell a victim, in a slight degree, to the green-eyed
monster when reading or hearing of his assistant’s successes
at the school? Were the mistakes made by this phar¬
maceutical chemist really serious mistakes as regards know¬
ledge of drugs and doses, or were they mistakes of another
kind, e.g. , forgetting to order something of which he had
sold out, or to weigh up some stock articles which were needed ?
Mistakes, if of this kind, might surely be pardoned in a man fresh
from school, and suddenly entering a brisk business after being
away for a few months, though doubtless Mr. Bessant would loo«.
at them through magnifying glasses of a rather jaundiced colour.
Possibly also the tuition from the unqualified (and twice rejected,
but so immeasurably superior) assistant took the form of show ing
this very inferior (but most pleasant and gentlemanly) pharma¬
ceutical chemist the places where the different articles were kept.
PHARMACEUTICAL JOURNAL.
[May 1, 189.7
386
The extent of Mr. Bessant’s knowledge of chemistry one cannot
doubt, his reference to the oxides of ethyl being sufficiently
enlightening. In conclusion I would say that I quite agree that a
knowledge of “First Aid” would be of especial use to chemists,
hut to put it on the examination schedule is scarcely consistent
with pharmacy proper.
April 27, 1897. One who Respects the Major Qual.
ANSWERS TO QUERIES.
Special Notice. — Scientific, technical, legal and general information required
by readers of the ‘Pharmaceutical Journal' will be furnished by the Editor as far
as practicable, but he cannot undertake to reply by post. All communications must be
addressed “Editor, 17, Bloo'insbury Square, London, W.C.," and must also be authen¬
ticated by the names and addresses of senders. Questions on different subjects should
be written on separate slips of paper, each of which must bear the sender’s initials or
pseudonym. Replies will, in all cases, be referred to such initials or pseudonyms,
and the registered number added in each instance should be quoted in any subsequent
communication on the same subject.
Botanical. — Fritillaria sp. [ Reply to J. W. H. L. — 92/10.]
Botanical. — Petasites vulgaris. [Reply to Femina. — 91/31.]
“Gum Manilla.” — Probably Manila copal is intended.
[Reply to L.A.R.— 91/37.]
Preparation for Horses. — The substance sent is magnesium
sulphate. [Reply to W. H. H. — 92/21.]
Growth of the Lower Jaw. — No, the development of the -
jaw is not interfered with at the age you state (15 years) if the
second molar is well erupted. [Reply to Nib. — 92/1.]
Reports on Essential Oils. — Both the publications you refer
to are obtainable only from Schimmel and Co. (Fritzsche Brothers),
Leipzig and New York. You may be able to procure copies by
writing to the former place. [Reply to J. F. L. — 92/9.]
Use of Library. — Obtain a form of recommendation from the
Librarian, 17, Bloomsbury Square, W.C., and return it after being
filled up and signed by a member of the Society or an associate in
business. [Reply to E. R. B. — 91/4.]
P.A.T.A. — You do not advance any fresh arguments in your
letter, and it does not appear that any good purpose will be served
by further prolonging the discussion upon the lines followed.
[Reply to Midlothian. — 91/42.]
Botany of the “Minor.” — You will only require the first
volume for some months, but the other is essential if you wish to
cover the whole ground. There is no absolute need to have any
other book, but it is always well to have studied more than one.
[Reply to R. M. — 90/37.]
Composition of Ointment for Ulcerated Leg. — The ointment
which you are asked to match appears to be carbolic acid, 1 5 ;
zinc oxide, 14 ; lanoline, 84 ’5. Doubtless the small amount of
phenol would have the analgesic effect you describe. [Reply to
Old Subscriber. — 90/12.]
Gas for Lethal Chamber. — Carbonic oxide, we believe, that
having been found by the late Sir B. W. Richardson the best narcotic
agent to employ, chloroform and carbon bisulphide being com¬
bined with it if necessary. Coal gas is the readiest and cheapest
for the purpose, but the risk of explosion when it is mixed with
air was found to be a disadvantage. [Reply to Canis.— 92/4.]
Real Lime Juice and Glycerin. — Yolk of one egg ; glycerin,
2 ounces ; oil of sweet almonds, 2 ounces ; tincture of quillaia, 2
drachms ; lime juice, 2 ounces ; oil of lemon, 20 minims ; oil of
bergamot, 5 minims ; orange-flower water to produce 8 fluid ounces.
Rub the yolk of egg smooth with the glycerin, add essential oils to
the quillaia and incorporate it with the egg mixture, then rub
in the almond oil a little at a time, then the lime juice in
small quantities at a time, and finally sufficient orange-flower water
to make up the volume. A sample made six weeks ago shows no
separation at the time of writing. [Reply to Femina. — 91/31.]
Chemical. — A is finely- divided metallic iron. B is a highly-
carburetted pig-iron. [Reply to Subscriber. — 90/38.]
Diploma. — Only pharmaceutical chemists are entitled to possess
and use diplomas stamped with the seal of the Society. The abbre¬
viation D.Ph.S. would be an absurdity. [Reply to Donovan. — 91/38.]
Methyl Blue and Methylene Blue. — Methyl blue belongs
to the rosanih'ne group, and is sodium triphenylrosaniline tri-
sulphonate ; it is not changed by acids, but is turned reddish
brown by alkalies. It is very different from methylene blue, which
is a chloride of tetramethylthionine ; it is not acted on so readily
by alkali as methyl blue. [Reply to J. A. — 90/34.]
Effect of Turpentine on the Urinary Secretion. — Tereberie
produces the curious effect which you allude to, causing a strong
violet-like odour to be given off by the urine, even more markedly
than turpentine. Some years back when there was a “boom” on
terebene for various chest affections, the writer had to prepare
large quantities of that substance. The vapour inhaled during
the process of polymerising and distilling was sufficient to give
rise to a very marked formation of the violet-smelling compound,
so much so that the circumstance was commented upon in forcible
terms by some of the laboratory operatives affected. We do nob
know that the body has been isolated. There is still room for a
good violet perfume, pace ionone. You may feel disposed to
experiment in this direction. Oil of eajeput and eucalyptus oil
produce very similar results. [Reply to E. A. W. — 89/20.]
INFORMATION WfiNTED,
Douglas Mixture for Fowls.— Can any reader oblige with the
recipe for this ? (89/32).
CORRECTIONS.
The Recent Nottingham Meeting.— Owing to the short time
available for revising the report of the discussion at the Nottingham
Chemists’ Association (Pharm. Journ., April 3, p. 306a), a passage
in Mr. Eberlin’s speech escaped correction. By transposition o£
the word “not” and omission of the words “but also,” the
passage appears to convey a meaning contrary to that intended by
the speaker, and obviously inconsistent with that of the context.
It would have been unnecessary to point out this error if it had nob
been made use of to support the statements that the Pharma¬
ceutical Journal has not been paid for by the members and
associates who constitute the Society, but has been the cause of
an “adverse balance” in the Society’s last financial statement and
“ a heavy loss to the Society,” which is alleged to be made good out
of the fees paid for examinations. A case seeking such support
must indeed be bad, as will be seen from the following correct
reading of the passage in Mr. Eberlin’s speech : — -
“But it should be borne in mind that the Journal depends for its income not
on advertisements and sales alone, but also on annual subscriptions,”
and from the confirmation of that reading afforded by another report
which appeared simultaneously in another place.
Students’ Page. — A botanical reader points out that the word
‘ ‘ oogonium ” as used in the notes on Cryptogams on page 296 is
incorrect. It should of course have been “oospore,” and we
regret that the writer of the paragraph referred to should have
omitted to correct what was an obvious slip of the pen when
revising the proof sent to him.
OBITUARY.
Solomon. — On February 26, John Solomon, Chemist and Drug¬
gist, late of Helston. Aged 82.
Barber. — On April 13, Robert Barber, Chemist and Druggist,
Manchester. Aged 52.
Presslie. — On April 13, Robert Dowell Presslie, Chemist and
Druggist, Aberdeen.
Thornton. — On April 16, John Thornton, Chemist and Drug¬
gist, Wedmore. Aged 77.
COMMUNICATIONS, LETTERS, etc., have been received from
Messrs. Bennett, Chambers, Cracknell, Dester, Durrant, Farr, Forrett, Foster,
Gardner, Glass, Grimble, Heap, Hill, Howarth, Jackson, Kemp, Kent, Laing,
Littleboy, Liverseege, Morrison, Norwood, Penistan, Poppelreuter, Prime,
Raphael, Bawling, Riding, Roach, Roberts, Squire, Venn, Wall, Williams, Wyatt.
May 8, 1897:] I
PHARMACEUTICAL JOURNAL.
387
ANNUAL
ORT OF THE COUNCIL.
Thefifty-sixth financial statement is submitted
Finance. with thisjeport. It is satisfactory to note that
the anticipations of the Council with reference
to the reduction of the balance on .the Journal account appear
to have been well founded, and it is confidently hoped
that the improvement will be continued. The figures relating to
School fees and the expenditure for carrying out the School
and Research work do not afford any definite indication of the
probable effect of the recent changes in the arrangement of the
Society’s educational work, but there is every reason to assume
that the School will in future be carried on with enhanced efficiency
and more economy.
During 1896, 1533 candidates presented
Examinations, themselves for the First examination, and 829,
or 54 -07 per cent, failed. The number
examined shows an increase of 133 as compared with the pre¬
ceding year, with a higher percentage of failures. For the
qualifying examination 1449 candidates were examined — 145 more
than in 1895 — whilst the percentage of those who failed to satisfy
the examiners remained about the same, namely, about 65 per
cent. For the Major examination 130 candidates — a decrease
of 16 on the previous year— presented themselves, and 53 ‘07
per cent, failed. Dr. Stevenson, in his latest report on the
examination conducted by the Board of Examiners for England
and Wales, says : — “I have to express my general satisfaction
with the manner in which the Minor or qualifying and Major
examinations are conducted, and with the great and steady im¬
provements which have been initiated by the Council of the
Society and carried out by the examiners during the last few years.”
Sir Douglas Maclagan has retired from the position which he has
held for many years, of Visitor on behalf of the Privy Council to
the Board of Examiners in Scotland, and the appointment of Dr.
Balfour Marshall to succeed him has been communicated to the
Council.
The resolution of the Executive of the North
Bye-Laws. British Branch relating to the Preliminary
examination to which reference was made in
the last annual report, has received the careful consideration of the
Council. It has been generally felt that the scope of the examina¬
tion should be extended, and the Council considers it undesirable
that the Society should continue to conduct the First examination
after June, 1900, but that registration as an Apprentice or
Student — a necessary condition before entering for the qualifying
examination — should be contingent upon the production of
certificates of general education, granted by approved examining
bodies. It has also been recommended that the fee payable by
candidates for the qualifying examination should include a sum
equivalent to a registration fee and be raised to ten guineas, with
a uniform fee of three guineas for re-examination on any sub¬
sequent occasion. New bye-laws for carrying these changes into
effect have been approved at three meetings of the Council, and
will be submitted to the members for confirmation at a special
General Meeting after the business of the Annual General Meeting.
The proposed new bye-laws are printed in the Pharmaceutical
Journal for April 10, p. 315.
The retirement of Mr. G. F. Schacht was
Council. much regretted by his colleagues, and his sudden
death a few months later is a heavy loss to the
Society. In June, Mr. Walter Hills was elected President of the
Society, and Mr. Carteighe was accorded a special vote of thanks
Vol. LVIII. (Fourth Series, Yol. IV.). No. 1402.
for the ability and self-sacrificing devotion which had charac¬
terised his long tenure of the presidential chair.
It is satisfactory to record that the Museum of the
Museum. Society is becoming increasingly useful to members
and students, the attendance during the past year
having been larger than during the previous year. It is recog¬
nised by the pharmaceutical world as one of the richest of its
kind, and rare drugs are frequently received from other
countries for identification, as well as applications for specimens
for special histological, chemical, and physiological research.
The Museum has also greatly benefited by exchanges with
pharmaceutical colleges and institutes, and many interesting
specimens have been forwarded by corresponding members,
and well-known travellers and botanists. The Museum of
the Society in Scotland has been largely added to by the acquisition
of two extensive collections of materia medica, to which attention
has already been directed in the J ournal.
The value of the Library for historical pur-
Library. poses is being continually proved, and the
importance of pharmaceutical literature has
been, during the past twelve months, shown by the presence of
members of the staff of the Royal Society engaged on the Cata¬
logue of Scientific Papers, who have been busy in cataloguing
some of the periodicals of which the Pharmaceutical Society
possesses the only complete sets in this country. The Council
continues to add important books to the collection, and has
to thank many generous donors for their gifts.
The Council has deemed it expedient to re-
SehOOl. sume the direct control of its School of Phar¬
macy. The change was facilitated by the
retirement of Professor Attfield, Professor Dunstan, and Mr.
Joseph Ince, and a scheme for reconstituting the School was ap¬
proved by the Council at its meeting in August. The
essential feature of the alterations made is the extension
to nine months of the period of instruction for the Minor
examination. A voluntary curriculum is thus established and
the status of the School as an institution in which a sound
education is afforded to students rather than one in which can¬
didates are prepared solely for examination, is proportionately
raised. The fees have been revised, and have been fixed with the
object of encouraging students to take the whole Course of
instruction. Two courses of study are now given, an Elemen¬
tary and an Advanced Course. The Elementary Course of
lectures and laboratory instruction commences in October and
is continued to the end of June, and the Advanced Course com¬
mences in October and terminates at the end of March. The
Professorial Staff consists of the Professor of Botany, the Professor
of Chemistry — who has also charge of the chemical laboratories and
the direction of the Research Laboratory — and the Professor of
Materia Medica and Pharmacy. The professors are assisted by
efficient demonstrators and assistants, appointed by the Council,
and in order that the Council may he constantly in touch
with the educational side of its work, the Library,
Museum, School, and House Committee annually nominates
one of its members to act as Visitor to the School, with authority
to attend the meetings of the staff, and to report from time
to time to the Committee. The reconstituted School was formally
inaugurated on October 4, when an interesting address on the aim
of Preliminary education was delivered to a large audience
by Mr. R. Brudenell Carter, F.R.C.S. The Council has satisfaction
in reporting that the 55th Session then opened has amply
justified anticipations, and successfully proved the existence of
a class to whom the acquirement of a sound technical
388
PHARMACEUTICAL JOURNAL.
[May 8, 1897
FINANCIAL STATEMENTS FOR 1896.
GENERAL FUND.
£ s. d. £ s. d.
Balance January X, 1896 : —
London and Westminster Bank .. .. .. .. 785 6 9
In hands of Chairman of Executive (Scotland) . . . . 5 15 7
- 791 2 4
Interest on Investments : — .
Ground Rents . . . . . . . . . . . . . . 149 16 8
Rent of 15, Bloomsbury Square . 1S7 10 8
- 337 7 4
Subscriptions : —
1334 Members, Pharmaceutical Chemists. . .. .. 1400 14 0
569 ,, Chemists and Druggists .. . . ... 597 9 0
1651 Associates in Business . . . . . . . . . . 1733 11 0
965 Associates not in Business . 506 12 6
841 Students .. .. . 441 10 6
4679 17 0
16 Life Subscriptions . 16S 0 0
Fees paid upon Restoration to the Society . . . . 6 13 0
- 4S54 10 0
Examination Fees : — -
1722 First Examination .. .. .. .. .. 3092 12 0
2 Modified ,, .. .. .. .. .. 12 0
1464 Minor ,, . 6135 IS 0
143 Major ,, . 397 1 0
9626 13 0
Registration Fees as Chemists and Druggists . . - . 14 14 0
Fees for Restoration to the Register . . . . . . 17 17 0
- 9659 4 0
School of Pharmacy — Students’ Fees . . . . . . . . . . . . 1367 2 0
London and Westminster Bank — An Advance, November, 1896 .. 1500 0 0
£ s. d
Annuities: — Mr. Elias Bremridge and Mr. Joseph Ince (1 quarter) .. 425 0 0
Carriage of Books and Parcels . 19 4 0
Certificates of Death . 21 10 6
Evening and other Meetings . 48 13 11
England
Examinations : — , and Wales. Scotland.
Minor, Modified, and Major : — -
Fees to Examinez'S and Ti'avelling Ex¬
penses . 1405 7 7 1009 18 6
Refreshments . . . . . . . . . . 60 13 4 53 2 1
Appai'atus, Drugs, Chemicals, Printing,
and sundry charges • . . . . . . 335 9 1 8S 17 6
1S01 10 0 1151 18 1
England and Wales . 1801 10 0
2953 8 1
First Examination : —
Fees to Superintendents, Hire of Rooms,
and other charges . . . . . . . . 340 2 3
Fees to the College of Preceptors ,. .. 198 19 0 539 1 3
- 3492 9 4
Fixtures Fittings, and Furniture . 19 16 0
Gas, Water, Coal, Cleaning Materials, etc . . 356 17 6
House Servants — Wages . . . . . . . . . . . . . . . . 285 4 4
Journal : — Balance of account . . . . . . . . . . . . . . 2228 1 9
School of Pharmacy : —
Stipends of Professors, Lecturez', Assistant Lecturer
azzd Demonstrators, and Wages of Porters . . . . S65 19 6
Subscription to Royal Botanic Gardens . 21 0 0
Apparatus, Chemicals, Specimens for Lectuz-e Classes,
Prize Medals, Certificates, and priziting and postizzg
prospectuses . 202 8 6
- 1089 S 0
Law Charges — Balance of account . 685 3 1
Library : — Librarian’s Salary . 26S 15 0
Purchase and Bizzdizzg of Books . . . . . . 90 16 5
Libraz’iazz attezzding Meeting of the Libi’ary
Association .. .. .. .. .. .. 10 10 0
- - 370 1 5
Museum : — -
Curator’s Salary . . . . . . . . . . . . 400 0 0
Assistant’s Wages . 52 0 0
Curator attendiizg Museums’ Association Meetizzg . . 10 10 0
Museum Report 1S93-4 . . . . . . . . . . . . 32 17 6
Specimezis, Bottles, and Sundries . . . . . . 40 15 7
- 530 3 1
Expenses in Scotland : —
Assistant Secretary — Salary . . . . . . . . . . 250 0 0
Taxes and Insurance . . .. .. .. .. .. 58 15 10
Members of Executive — Travelling Expenses, etc. . . 33 13 6
Fuel, Light, Water, Cleaning, Service, and Miscellazzeozzs
Expenses . . . . . . . . . . . . . . 305 11 2
- 64S 0 6
Postage : — General . . . . . . . . . . . . . . 219 11 2
Journal.. .. .. .. .. .. .. 875 4 6
- 1094 15 8
Pharmacopoeia Committee of the Society (paid on accountof) .. .. 41 5 5
Provincial Education (Gz-ant to Livez'pool Pharmaceutical Students’
Society) .. IS 0 0
Register — Balance of Account . . . . . . . . . . . . 9 2 7
Rent, Taxes, azid Insurance of Plate Glass . 750 2 10
Repairs azzd Alteratioizs . . . . . . . . . . . . . . . 601 13
Stationery, Engraving, Priziting and Office Expenses . 247 14
Calendar — Balance of Account . . . . . . . . . . . . . . 78 17
Salaries : — Secretary and Registrar, and Clerks . . . . . . . . 1629 19
Research Laboratory . . . . . . . . . . . . . . . . 381 17 ,
Herbarium azid Council Medals, and Sundries . . . . . . . . 1117 8
Travelling Expenses — Council and Committees . . . . . . . . 504 8 7
Refreshments for Council . . . . . . . . . . . . . . 47 2 8
Interest on Advance from Bankers . . . . . . . . . . . . 33 10 8
London azid Westminster Bank — Amount repaid April, 1896 .. .. 1500 0 0
Repaid to Treasurer — Amount due to him January 1, 1896 .. .. 13 18 9
Balance December 31, 1S96 : — ■
London and Westminster Bank .. .. .. .. 1243 8 10
In hands of Chairman of Executive (Scotland) . . . . 72 4 8
In Treasurer’s Hands . . . . . . . . . . . . 3 116
- - 1319 5 0
£18,509 5 8
£18,509 5 8
-T C O C" M
MAY 8, 189?]
PHARMACEUTICAL JOURNAL.
389
BENEVOLENT FUND.
Balance, January 1, 1896
London and Westminster Bank . . . ,
In Treasurer’s hands .
Interest on Invested Capital and Ground Rents
Subscriptions .
CURRENT ACCOUNT.
£ s. d.
471 2 6
17 8
1051 1 0
1739 14 4
£3263 5 6
A nnuitants.
35 at £50 per annum for 4 quarters . .
9 at £40 „ „
1 at £35 ,, ,, ....
2 at £50 ,, 3 ,,
1 at £50 ,, 1 quarter
£ s. d.
1750 0 0
360 0 0
35 0 0
75 0 0
12 10 0
Grants.
Members and Associates of the Society and Registered
Chemists and Druggists (27) . . .. .. 287 0 0
Widows of ditto (25) . . . . . . . . 266 0 0
Secretary’s Casual Fund..
Interest on £1000 borrowed from the Orphan Fund
Printing, Stationery, and Postage .
Balance, December 31, 1896 : —
London and Westminster Bank . .
In Treasurer’s hands
£ s. d.
2232 10 0
553 0 0
10 0 0
35 0 0
40 10 8
386 7 10
5 17 0
£3263 5 6
Balance, Jan. 1st, 1896 : — London and Westminster Bank
Donations and Legacies
DONATION ACCOUNT.
. . 430 4 5 Purchase of £1000 Consols
. . 1024 5 0 Balance, Dec. 1st, 1896 : — London and Westminster Bank
£1454 9 5
1108 16 0
345 13 5
£1454 9 5
Balance, Jan. 1st, 1896 : — London and Westminster Bank
Subscriptions
Interest on Invested Capital
Interest on £1000 lent to the Benevolent Fund
ORPHAN FUND.
(Founded by Thomas Hyde Hills, 1891.)
. . . . 82 9 9 London Orphan Asylum (Minett) .
.. .. 18 10 0 Balance, Dec. 31st, 1896 London and Westminster Bank
9 15 0
35 0 0
£145 14 9
30 0 0
115 14 9
£145 14 9
AUDITORS’ REPORT.
We, the undersigned Auditors, have examined the accounts of the Pharmaceutical Society of Great Britain, as presented in the Financial
Statements of the General Fund, the Benevolent Fund and the Orphan Fund Accounts, and find them correct. We have inspected the Deeds
relat’ng to the House Property and Ground Bents named below, and also find that there were standing to the account of the Society at the Bunk
of England, and in the hands of the Society’s Bankers, on the 31st December, 1896, the following, viz. : —
'Freehold Ground Rents at Paddington Green, London, W,, cost . £5551 5 6
House in Edinburgh, cost . . 1931 10 0
General Fund . „ ,, Additional Building, cost . 3111 4 9
Leasehold Premises : — Galen Place, cost . 10,fi06 10 2
,, 16 and 16, Bloomsbury Square, cost . 9527 5 3
Benevolent Fund.
30.727 15 8
Two and three-quarters per cent. Consols . £2050 0 0
Freehold Ground Bents at Strawberry Hill, cost . £1020 12 6
Do. Battersea, cost . 12,213 0 0
Do. Broomwood Park Estate, cost . 7454 7 10
Do. West Kensington, cost . 5809 2 1
- - 26,497 2 5
100 0 0
100 0 0
St. Paul, Minneapolis and Manitoba Railway 4 per cent. Bond . . .
Chemists’ Aerated and Mineral Waters Association, Limited, fully paid-up £1 Shares
28,747 2 5
Orphan Fund . Two and three-quarters per cent. Consols . . . . . .
In addition to the above the following Securities were standing to the credit of the Society on December 31st, 1896 : —
Pereira Memorial Fund...
Bell Memorial Fund .
H anbury Memorial Fund
Redwood Memorial Fund . Great Indian Peninsula Railway Stock
Hills Prize Fund . Russian Bonds .
| Two and three -quarters per cent. Consols
355 O O
C ICO O 0
2 60 O O
L 400 O 0
400 O O
318 8 O
Manchester Pharmaceutical Asso- | Manchester Ship Canal Co. 4 per cent. Debentures
ciation Scholarship Fund . f Two and three-quarters per cent. Consols .
The Burroughs Scholarship . 4 per cent. New Zealand Consolidated Stock . .
February 23, 1897.
700 0 0
52 4 6
- 752 4 6
. 720 O O
S. LLOYD STACEY,
CHAS. UMNEY,
F. HARWOOD LESCHER,
FRANCIS YATES,
l Auditors,
390
PHARMACEUTICAL JOURNAL.
[May 8, 1897
education for their sons is of higher import than a hastily
gained minimum of knowledge requisite to pass an examination.
The Council has always willingly identified
Provincial Edu- itself with every effort for the promotion or en-
eation. couragement of pharmaceutical education in
provincial centres, and during the past year its
practical sympathy with local activity in this direction has been
shown by a grant of £20 to the Liverpool Pharma¬
ceutical Students’ Society. This has been expended in the
purchase of a materia medica cabinet and specimens, which
have been taken charge of by the authorities of the Liverpool
University College for the use of students in the Liverpool district,
and should be of material assistance in supplementing the pharma¬
ceutical instruction, for which special provision has been made at
the College.
The Council records with pleasure
Scholarships, that it has been able to realise the
wishes of the founder of the Manchester
Pharmaceutical Scholarship by the appointment of a Man¬
chester Scholar. It is expected that this Scholarship will at¬
tract more competitors as it becomes more widely known
in the district to which it applies. The Burroughs Memorial
Scholarship, to which reference was made in last year’s report,
has now been established. The conditions under which the
scholarship may be competed for and held have been formulated
and are published both in the Journal and the Calendar. The Council
trusts that this, the latest addition to the Society’s educational
endowments, will stimulate pharmaceutical chemists to avail
themselves of an opportunity to enter upon a post-graduate course
of instruction in advanced chemistry and pharmacy with a view to
fitting themselves for the conduct of original investigations in
those subjects.
Mr. Thomas Tickle, who has been appointed
Research. the Salters’ Research Fellow, Mr. Wilfrid
Lean, who was appointed Redwood Scholar by
the Council in July, and Mr. R. M. Stearn are conducting investi¬
gations in the Laboratory under the direction of Professor J.
Norman Collie.
The session in London was opened by a
Evening lecture on “The Discovery of Argon and
Meetings. Helium ” by Dr. J. Norman Collie,
F.R.S. — the Professor of Chemistry in the
Society’s School. On a subsequent evening papers were read by Mr.
David Howard on the “ Estimation of Quinine,” and by Mr. E. M.
Holmes on “ The Trees Yielding Myrrh and Gum Arabic.”
Mr. A. C. Seward, M.A., of Cambridge, gave an illustrated lecture
on “Fossil Plants,” which was much appreciated, and at the last
meeting of the session valuable papers were contributed by Mr.
W. Martindale on ‘ ‘ Preservatives of Pharmacopceial Prepara¬
tions” and by Mr. J. C. Umney on “The Commercial Varieties
of Fennel and Their Essential Oils.” The meetings have been
characterised by a considerably larger attendance than usual.
During the year about 400 cases of infringe-
Legal. ment of the Pharmacy Act have been brought to
the notice of the Council and dealt with. A
•risumi of the cases which came into court is published in the
Pharmaceutical Journal for January 2, 1897. Beyond occasionally
exhibiting the legal difficulties placed in the way of the Society
these cases, with one exception, present no feature for special
comment. The exception is the case of the Society v.
Fox, an unregistered person who was proceeded against in
respect to a sale of Kay’s Compound Essence of Linseed — a prepara¬
tion of morphine. The defence raised was that the preparation
came within the exemption provided in Section 16 of the Pharmacy
Act for “patent medicines,” and the point at issue was the definition
of a patent medicine. The compound essence of linseed had
been the subject of Letters Patent, but the patent had, by the non¬
payment of fees, lapsed twenty years previously. Relying
upon the words of the Medicine Stamp Act, imposing a stamp
duty on medicines at any time prepared under authority of Letters
Patent, the defendant contended that the grant of a patent
for a medicine conferred patent privileges thereon for all time. The
learned County Court Judge, however, held otherwise, and decided
that the exempting words of Section 16 did not cover Kay’s Essence
of Linseed. This ruling was contested by the defendant, and an
appeal was carried to the Queen’s Bench, where it was very sum¬
marily dismissed with costs.
The action of Sheriffs in Scotland before whom certain cases of
infringement have been brought, has increased the difficulty of
carrying out the provisions of the Pharmacy Act north of the
Tweed. The matter is receiving the careful consideration of the
Council.
The income from subscriptions shows an
Benevolent improvement of less than £100. This cannot
Fund. be considered a large increase when the
annual additions to the roll of registered
persons is borne in mind. The total amount received last year
in subscriptions and for interest was £2790, and the expenditure
in casual grants and for annuities was £2795. It is regrettable
to have to record that in January the Treasurer had not enough to
the credit of the current account to pay the amount of the
annuities then due, and special efforts had to be made to
supplement the available resources of the Fund. The Council
confidently hopes that this condition of things will be
removed during the ensuing year, and that the efforts being
made in connection with the Decennial Festival Dinner
and in commemoration of Her Majesty’s Diamond Jubilee
will contribute to the more general participation of registered
persons in the maintenance of the Fund, which exists solely for
their benefit. The Council has pleasure in recording the good
work done by local secretaries and local associations on behalf of
the Fund, and highly appreciates the valuable assistance thus
rendered. During the year £450 was received from the estate of
G. Dudgeon of Nottingham, and a legacy of £9 under the will of a
lady whose brother was a chemist. The late H. A. Thomas also
left the Fund £100, and another divisional secretary recently de¬
ceased — the late Geo. Nind — has bequeathed £2000 for the benefit
of those who are unfortunately compelled to look to the Fund for
help.
The report of the Executive of the North
North British British Branch of the Society presented
Branch. to the Council at its May meeting affords
evidence of the efficiency and loyalty with
which the Society’s work in Scotland is conducted.
The following deaths have to be recorded : —
Obituary. Dr. J. Langdon Down, Dr. Edmund Russow,
Honorary Members; Dr. Trimen and Baron
Ferdinand von Mueller, Corresponding Members ; Thomas Earee,
Founder ; G. F. Schacht, S. C. Betty, and Marshall Leigh, former
Members of the Council ; J. B. Parkin (Ripon), F. Codd (Devonport),
W. B. Stonham (Maidstone), E. S. Bradley (Ashbourne), E. H.
Dyer (Honiton), and W. Sarsfield (Durham), Local Secretaries;
and H. A. Thomas (City), W. Gulliver (St. George’s, Hanover
Square), and G. Nind (Wandsworth), Divisional Secretaries.
May 8, 1897]
PHARMACEUTICAL JOURNAL
391
PHARMACEUTICAL SOCIETY
Chemist and Druggist.
John Christie, of Glasgow, who was in business before August 1,
1868, having tendered his subscription for the current year,
was elected a “Member” of the Society.
MEETING OF THE COUNCIL.
WEDNESDA Y, MA Y 5, 1897.
Present :
Mr. Walter Hills, President.
Mr. John Harrison, Vice-President.
Messrs. Allen, Atkins, Bateson, Bottle, Carteighe, Corder, Cross,
Gostling, Grose, Hampson, Johnston, Martindale, Newsholme,
Savory, Southall, Symes and Young.
The minutes of the meeting on April 7, and also of the special
meeting on April 28, were read and confirmed.
The International Congress in Brussels.
The President said he suggested at the last meeting that dele¬
gates might be appointed to-day to the International Congress at
Brussels, but though he should be quite willing to take the names
of any gentleman who had made arrangements to attend, he
thought, on the whole, it would be more convenient to defer
making the appointment until next month, when delegates would
be appointed to the British Pharmaceutical Congress, which held
its meeting in Glasgow nearly at the same time, and when gentle¬
men would be more likely to have made their arrangements for the
autumn.
Announcement of Deaths.
The President announced that since the last meeting of the
Council one of the founders of the Society had been called to his
rest in the person of Mr. Thomas Earee, of Staines, who for fifty-
six years had regularly subscribed to tbe Society. He also men¬
tioned the death, on April 11 last, of Professor Edmund Russo w,
an honorary member, who was Professor of Botanyand Director of the
Botanical Gardens at the University of Dorpat. Professor
Russow was the professor under whom Professor Greenish had
worked for some tifne ; his principal work was in anatomical
botany and the comparative anatomy of plants, in which work he
was admitted to be facile princeps. The Council would condole
with the widow and family in the loss which they had sustained.
As he was only fifty-six years of age the loss of such an able man
was all the more to be regretted.
Diplomas.
The undermentioned, being duly registered as pharmaceutical
chemists, were granted diplomas stamped with the seal of the
Society : — -
Coupland, Henry Snart.
Coverdale, Arthur Edward.
Drust, John Hubert.
Elkington, Charles John.
Goodall, Frederic Charles.
Hopkins, John Sidney.
Hughes, William Griffiths.
Knowles, William Richards.
Lee, Harry Lancelot.
Lewis, Richard Rice.
Lloyd, Thomas Henry.
Lumley, Harold.
Mallaband, William Henry.
Saunders, Alfreton Woods.
Stearn, Ralph Marmaduke.
Sutcliffe, Lot Bains.
Thomas, James Douglas.
Umney, Ernest Albert.
Walker, Albert Storrs.
Woodward, Harrison.
Rattray, David Smith.
Election of Members.
The following, having passed the Major examination and
tendered their subscriptions for the current year, were elected
“ Members” of the Society : —
Pharmaceutical Chemists.
Election of Associates in Business.
The following, having passed their respective examinations, being
in business on their own account, and having tendered their sub¬
scriptions for the current year, were elected “ Associates in Busi¬
ness ” of the Society : —
. Minor.
Blyth, William Brew A. ; Leith.
Bowness, Samuel Wesley ; Ripponden.
Brown, John ; Melrose.
Carpenter, Joseph Edmund ; Sandwich.
Crawford, David ; Glasgow.
Curtis, Michael ; London.
Darling, J ohn M. ; S. Shields.
Eden, William James ; Manchester.
Giles, Lewis John ; Folkestone.
Gilmour, Andrew ; Manchester.
Harriman, Edwin ; Liverpool.
Harry, Elias Hamilton ; Clapham.
Hay, William Fowlie ; Aberdeen.
Head, George ; Deal.
Hodgson, John Duncanson ; London.
Hughes, William ; Manchester.
Hull, John Heber ; Tadcaster.
Humfrey, William Henry ; Deal.
Jenkins, Owen John ; Cardiff.
Jennings, William Henry ; Hoylake.
Jones, William ; Liverpool.
Keeley, James Philip ; Blackpool.
Littler, John ; Chesterton.
Mann, Joseph ; Lowestoft.
Marshall, Richard Harrison ; Bradford.
Maunder, John H. ; Teignmouth.
Neil, William ; Fettercairn.
Plumstead, Fred. G. E. ; Attleborough.
Stone, Ernest Frederick ; Exeter.
Swainson, John Wm. B. ; Devonport.
Wakefield, John Henry ; Birmingham.
Wallas, Thomas Irwin ; London.
Watkinson, Wm. H. ; Little Hulton.
White, Alexander A. ; Auchtermuchty.
Williams, George Alfred ; Manchester.
Williams, Harry Griffith ; Manchester.
Wright, George Victor ; Edinburgh.
Young, James R., jun. ; Edinburgh.
Modified.
Spyer, Newton ; S. Kensington. | Wheeler, Frederick Wm. ; Southsea.
Election of Associates.
The following, having passed the Minor examination and
tendered or paid as “Students” their subscriptions for the
current year, were elected ‘ ‘Associates ” of the Society : —
Arber, Alfred Preston ; Malvern.
Ashdown, William Percy C. ; Brighton.
Barlow, Thomas Oldham ; Bowdon.
Barrett, Henry William ; Poplar.
Battle, Ernest William C. ; Manchester.
Bawcutt, Frank Frederick ; London.
Bowdler, Ernest Harper ; Albrighton.
Bowman, Alexander N. ; Cardenden.
Bromley, Albert William ; Hull.
Burnett, John ; Pickering.
Cooper, Herbert Edward ; Kettering.
Dannatt, Philip ; Hull.
Dowdy, Sidney Ernest ; Kennington.
Dun-ant, George Stuart ; London.
England, Herbert ; Scarborough.
Eustace, Robert George ; London.
Evans, Arthur E. ; Moretonhampstead.
Forrest, James Lindsay ; Edinburgh.
Forster, William ; Seaham Harbour.
Gair, Emmeline Annie ; London.
Gayton, Ethel ; Hampstead.
Gwilliam, John Everall ; Warminster.
Hamer, Enoch Thomas ; Southport.
Hankinson, Herbert S. ; Liverpool.
Hirst, Frederick B. ; Batley Carr.
Hodgson, Baron Cuthbort ; Halifax.
Hooper, Joseph ; Okehampton.
Jeffery, George Golder ; Tring.
J effs, Richard Thomas ; Gloucester.
Jones, Edward Rees ; Oswestry.
Jones, Stephen; London.
Kerruish, Thomas Maltby ; Douglas.
King, Frank Herbert ; London.
Knight, Thomas ; Reading.
Knowles, John Thomas ; Lancaster.
Lenfestey, L. d’Estreville ; London.
Lloyd, Henry Bright ; Cheltenham.
Lounds, William Beaver ; Grantham.
Lowson, William ; Driffield.
Matson, Joseph ; Stockton-on-Tees.
Mellor, William Gilbert ; Warwick.
Milner, Jonah ; Consett.
Parker, Herbert Thomas ; Cambridge.
Peck, John Wicliffe ; Clapham.
Prescott, John ; Butterwick.
Purnell, Austin ; Clevedon.
Si viter, William Oscar B. ; Birmingham-
Skeat, Charles ; Plymouth.
Skinner, Ernest Pape ; Boston.
Sutherland, Alexander G. ; Dundee.
Thompson, Edward ; Middlesboro’.
Thompson, Sidney C. ; King’s Lynn.
Wade, Margaret Callander ; Larbert.
Whysall, Edward Searson ; Grantham.
Windemer, Oscar Roxburgh ; Pembury.
Woods, Benjamin A. ; Kings Lynn.
'Election of Students.
The following, having passed the First examination and
tendered their subscriptions for the current year, were elected
‘ ‘ Students ” of the Society : —
Bowden, Harold ; Manchester.
Coupland, Henry Snart ; Islington.
Coverdale, Arthur E. ; S. Kensington.
Currie, Archibald ; Leith.
Dewhirst, John Arthur ; Brixton.
Hopkins, John S. ; Stow-on-the-Wold.
Lee, Harry Lancelot ; London.
Lewis, Richard Rice ; Aberdovey.
Lumley Harold ; New Cross.
Mallaband, William H. ; Sheffield.
Rattray, David Smith ; Aberdeen.
Saunders, Alfred Woods ; Dedham.
Stearn, Ralph Marmaduke ; Cambridge.
Sutcliffe, Lot Bains ; Goole.
Taylor, Archibald L. ; S. Lambeth.
Thomas, James Douglas ; Sydenham.
Umney, Ernest Albert ; Sydenham.
] Walker, Albert Storrs ; Kendal.
Armstrong, Henry Swan ; Dumfries.
Cannon, Herbert Henry ; Lb k card.
Davison, Joseph ; Spennymoor. .
Dawson, Robert Hilliard ; Wigan.
Fullerton, David Noble ; Aintree.
Green, Harold Walter ; Birmingham
392
PHARMACEUTICAL JOURNAL,
[May 8, 189?
Guard, Harry Ernest ; Kennington.
Hallsworth, Harry M. ; Oldham.
Pad wick, Kingsley John ; Brighton.
Roberts, William R. ; Linthwaite.
April, 1895 to March, 1S96
„ 1896 „ 1897
„ 1494
.. 1242
Hawkes, Frederick ; Kennington.
Houghton, George Smith ; Leeds.
Humphreys, Julian ; London.
Hustler, George Herbert ; Horton.
Jones, Hugh ; Llanfairfechan.
Little, Robert ; Wootton Bassett.
Nixon, John Hobart ; Loughborough.
Watts, Wil
Rouse, William Henry Broom ; Sidcup.
Sloman, Courtenay ; Torquay.
Smith, Harold Saunders ; Horsham.
Tinsley, Samuel Hilton ; Widnes.
Vickery, William Robert ; Plymouth.
Walter, William H. ; Newcastle; Staffs.
Wamsley, William Bunting ; Stockport,
n ; Dumfries.
Restorations to Register.
The names of the following persons, who have severally made the
required declarations, and paid a fine of one guinea, were restored
to the Register of Chemists and Druggists : —
Angus Sinclair Brown, 375, Cleethorpe Road, New Clee, Grimsby.
Robert Lamb, The Hospital, Altrincham.
Charles Nicholls, Bow Street, Langport.
Andrew Paul, 16, Glasgow Road, Burnbank, Hamilton, N.B.
Several persons were restored to their former status in the
Society upon payment of the current year’s subscription and a
nominal restoration fee of one shilling.
Report of the Executive of the North British Branch.
The following report was read : —
“ The Executive of the North British Branch has now to submit the following
report on the work of the year, March, 1896, to March, 1897.
“ At a meeting of Executive held on April 17, 1896, it was arranged that the
annual election should take place on Friday, June 19, 1896, and the present
Executive was accordingly elected at a meeting of Members and Associates in
Business of the Society residing in Scotland, held on the above date.
“ The Executive has held three meetings during the year. At the first meeting
on July 3, 1896, Mr. James Laidlaw Ewing, Edinburgh, was elected Chairman,
and Mr. William Little Currie, Glasgow, Vice-Chairman.
“ The resident members, with the Chairman and Vice-Chairman, were appointed
a General Purposes Committee to attend to business arising between meetings of
Executive, or remitted to them by the Executive.
“ A Committee was also appointed to prepare a report on the Nomination of
Examiners.
“The General Purposes Committee has met three times, and has had charge of
the Evening Meetings and the arrangements connected with the purchase of the
Scoresby- Jackson collection of materia medica from the representatives of the
late Dr. T. A. G. Balfour, and the transference of the Materia Medica Museum of
the Royal College of Physicians to the custody of the Society to be kept in the
Society's premises in Edinburgh.
“ The Committee for Nomination of Examiners met twice, and reported to the
Executive on November 26, 1896, when the following were nominated for election
by the Council as the Board of Examiners for Scotland for 1897 : — Isaac Bayley
Balfour, Regius Professor of Botany in the University of Edinburgh ; John
Gibson, Professor of Chemistry in the Heriot-Watt College, Edinburgh ;
Alexander Davidson, Montrose ; James Laidlaw Ewing, Edinburgh ; Jonathan
Innes Fraser, Edinburgh ; Thomas Maben, Hawick ; John Nesbit, Portobello ;
and John William Sutherland, Dumfries.
“ The Financial Statement for the year ending December, 1896, showing a total
expenditure of £1533 10s. lid., as compared with £2550 17s. id. for the previous
year, has already been forwarded to the Council. The expenditure for 1S95
included special expenditure of £1149 9s. 9d. in connection with new buildings
required for examination purposes, thus making the ordinary expenditure
£1401 7s. 7 d. There has been a decrease of £26 10s. in the item of Fuel, Light,
and Water, which was exceptionally high during the previous year, owing to
work connected with new buildings. There is also a decrease of £77 15s. lOd. in
the cost of chemicals and apparatus for examinations. The nett increase of
£132 3s. id. over last year is entirely due to the larger examinations.
“ The following particulars indicate that the departments connected with the
branch continue in a satisfactory state : —
“ The Examinations. — The number of candidates for examination continues
large, and these large examinations have been conducted with ease and comfort
in the new examination premises.
“ During the year 16 Major Candidates were examined, of whom 4 passed and
12 failed ; and 623 Minor Candidates were examined, of whom 211 passed and
412 failed.
“ There has been a slight decrease in the number of Major candidates, 16 as
compared with 18, and there has been a considerable decrease in the number of
passes, 25 per cent., as compared with 44‘4 per cent, last year.
“The number of Minor Candidates again shows a considerable increase, 623 as
compared with 540 last year. The results show a further unsatisfactory decrease
in the percentage of passes, 33'87 per cent, as compared with 40 per cent, in the
previous year.
“ Evening Meetings. — The Executive regret to have to report that it has not
been found possible to hold more than two Evening Meetings in Edinburgh
during the past winter session. An opening meeting had been arranged to be
addressed by Professor Patrick Geddes, but at the last moment he found it
impossible to fulfil the engagement. It has been found that Friday nights are
unsuitable for these meetings, owing to the number of other engagements in
Edinburgh on that night, and the Executive may have to consider the alteration
of the night for next session. The Executive has to express thanks to those
gentlemen who contributed papers for the meetings that were held.
Library. — “ The Library continues to grow, and during the year several valuable
books have been added, mostly by purchase, and a few also by donation. The
number of volumes circulated during the year is seen from the following
statement : — .
Decrease . 252
“This shows a decrease of 252 volumes in the total circulation. On the other
hand, there is a gratifying further increase in the number of volumes circulated
to provincial readers. During the year 1895-96, 140 volumes were circulated to
readers outside Edinburgh and Leith ; during the year 1896-97, 185 volumes have
been so circulated, showing an increase of 45 volumes.
“While the lending of books shows a decrease, it is right to say that the
enrichment of the Library in recent years by the addition of a considerable num¬
ber of valuable standard books of reference and bound volumes of the leading
chemical, medical, and pharmaceutical periodicals, has maintained and largely
increased the use of the Library for purposes of reference by members, associates,
and students, and also by scientists, medical practitioners, and teachers.
“The Executive has to record thanks to those gentlemen who have given
donations of books during the year.
“ Museum. — The Executive has again to record thanks to several donors of
specimens. The chief of the events of the year in connection with the Museum
are : —
“1. The purchase of the Scoresby- Jackson collection of materia medica in
December for the sum of £45, for which the Executive is indebted to private
subscribers to the extent of £27 16s., and to the Council for the balance of £17 4s.
This collection was begun and largely made by Sir Douglas Maclagan and then
passed into the hands of the late Dr. Scoresby -Jackson, and ultimately became the
property of the late Dr. T. A. G. Balfour. It contains several specimens of con¬
siderable historical, commercial, and scientific interest.
“ 2. The presentation to the Society of their Materia Medica Museum by the
Fellows of the Royal College of Physicians, Edinburgh, to be preserved in the
Society’s house in Edinburgh. The collection is now in process of being trans¬
ferred.
“The students’ specimens have just been examined and put in good order.
Some which had become deteriorated by handling are at present being renewed.
“ The Attendance. — Under this heading there is nothing noteworthy to record.
The Library and Museum continue to attract large numbers of visitors, and the
Society’s House is much appreciated as a convenient place of call by members of
the craft from various parts of the country.
“ House. — The Society’s premises in Edinburgh are in thorough repair and good
order. The proposals for re-adjustment of premises have been delayed for fuller
consideration after the Executive has got full possession of the collections now
being added to the Museum.
“ Edinburgh, April 23, 1897. “James L. Ewing, Chairman."
The President moved that this report be received and entered
on the minutes. It showed the care with which all matters con¬
nected with the business of the Society in the North was conducted
by the Executive, under their very excellent Chairman, Mr. Laidlaw
Ewing. He need only call special attention to the very excellent
collections of materia medica which had been acquired, the arrange¬
ments for the care of which had necessitated some delay in the
re-arrangement of the Society’s premises. The collection of the
Royal College of Physicians especially was one of considerable mag¬
nitude, and some care and thought were necessary in providing
for its proper custody.
Dr. Symes said the report was most satisfactory, but he wished
to call attention to the large percentage of failures disclosed by it.
He thought it would be a good thing to get some kind of return of
the percentages of failures in particular subjects. With regard to
having professorial examiners for special subjects, there was
always a little danger of a professor in any one subject thinking
that his subject was the one in which the candidate should be
more efficient than anything else. He had heard that some of the
substances given for analysis were rather outside what might be
expected by ordinary candidates. It might be that the large
percentage of failures had been in the practical subjects, and not
in the technical ; therefore, it would be very satisfactory to know
in what subjects the failures occurred. He would not ask for this
at the present time, but some kind of a return at a future date
might be of use.
The President replied that the information desired by Dr.
Symes would probably be supplied in the Report that Sir Douglas
Maclagan or the present Visitor representing the Privy Council.
He believed that such figures were given in the Reports presented
from time to time by the Goverment Visitor for the Board for
England and Wales. It would be noticed that there were a
large number of failures in what they chose to call the purely
practical subjects, dispensing and so on, as well as on the chemical
side. The failures were pretty generally distributed over the
different subjects. As far as he could judge the special examiners
alluded to by Dr. Symes were very anxious to do all they could
to bring out the information which the candidates possessed on the
particular subjects, and he thought the candidates were treated
with every consideration by them.
Dr. Symes said his grievance was not one from any candidate or
he should not have thought of bringing it forward. They trusted
their examiners thoroughly, and had every confidence in them,
but they did not want a professor of chemistry to feel that a man
was going to live by pure chemistry alone, and the same with the
Mat 8, 1897.]
PHARMACEUTICAL JOURNAL.
393
professor of botany. One always wanted to guard against a
danger of that kind.
The President said it was very difficult to discuss this matter
in public, but he would say that it had been generally accepted by
the Council that the examination should be something more than
on merely practical questions, and that the examination in
chemistry, botany and so forth, should be a general test of the
knowledge of the candidate up to a reasonable point.
The Proposed New Bye-Laws.
The President moved that the proposed new bye-laws be taken
as read. This was seconded by Mr. Hampson and agreed to.
The President then moved that the proposed new bye-laws,
which were read a first time on April 7, a second time on April
28, and were published in the Pharmaceutical Journal for April
10, 1897, be confirmed.
Mr. Grose seconded the motion.
Mr. Bateson said he had paid great attention to the criticisms,
both favourable and adverse, which these proposals had evoked,
and was glad to find that opinion was almost if not quite
unanimous with regard to the present Preliminary examination
being inadequate, and that the proposed extended scope was
meeting with universal approval. But 'the same unanimity did
not exist with regard to the raising of the fee for the Minor
examination, and he was not altogether surprised at it.
The Council had discussed the matter again and again,
and the proposal had more than once been passed ncm. con. , which
must be highly satisfactory ; but there were two sides to the ques¬
tion, and it was suggested that it might prevent young men who
were educated and eligible from going into pharmacy, and rather
lead them to take up other professions where the training was not
more costly, either in money or brain power. To that it was
replied that the five-guinea fee was not at all commensurate with
the advantages conferred, because when a man was once placed on
the Register he secured a life protection. He now knew more than
he did twelve months ago as to the amount of care and trouble
bestowed on business matters. It would be impossible for anyone
to sit through a single meeting of the General Purposes Committee
without seeing the vast amount of complex legal work which was
constantly going on. But he was bound to say that
in country places the question of cui hono ? was certainly
felt very strongly. There were gentlemen round that table who
had fashionable dispensing establishments and profitable proprie¬
taries, to whom it was not a matter of much moment whether the
fee was large or small, but in country districts with the present
keen competition it was sometimes very difficult to keep a business
going at all. There were scores of places where a few years ago
two or three assistants were kept, but where now they could not
afford to keep one, and, as had been mentioned on a former occa¬
sion, there was great difficulty in getting apprentices. Still, not¬
withstanding those considerations, he believed the proposed change
was right, and he should support it. He believed it was right,
and in the interest, not only of those who were already members
of the craft, but also of those who were about to become so, and he
might say that his vote would be an independent, a conscientious,
and, he hoped, an intelligent one, not influenced by any of the
leading lights round the table. He had never considered that the
raising of the fee was intended to bolster up the finances of the Phar¬
maceutical Society, and a sufficient refutation of such a suggestion
might be found in the financial statement, which had been placed
on the table. He believed the result of passing these bye-laws
would be to consolidate the interests of the craft, and to unite
them more closely together as one corporate body. He believed
that in the future great things would have to be done by the
Council, and that what they were now doing would greatly assist
them in their efforts. He made these remarks because he was one
of the junior members, whom he thought had been rather reflected
upon in a certain quarter, or he should not have troubled the
Council.
The President said there was no need for an apology on Mr.
Bateson’s part ; they had all been delighted to hear the words he
had given utterance to, and were glad to think that one of the
latest additions to the Council had, on the merits of the question,
come to the decision that the proposed new bye-laws were for the
interests of the body generally. Before putting the resolution he
should like to say that the Council had received notices of several
meetings at which resolutions had been passed in favour of the
new bye-laws. The meetings were held by the chemists’ associa¬
tions at Sunderland, Hull, Liverpool, and Plymouth. They
would be glad to hear these intimations of approval of the
course they were taking from their friends in the country.
The resolution was passed unanimously.
Report of Finance Committee.
The President said there was nothing special to call attention
to in this report. The receipts were, no doubt, rather larger during
the last month, but that was owing to the subscriptions from the
members. He had received a letter from Messrs. Corsellis, the
solicitors to the executors of the late Mr. George Nind, of Wands¬
worth, returning his diploma and giving notice of the fact that the
deceased had left a legacy of £2000 to be applied for the purposes
of the Benevolent Fund of the Society.
The report was unanimously agreed to.
Benevolent Fund Committee.
The report of this Committee included a recommendation of
grants to the amount of £35 in the following cases : — -
The widow (52) of a registered chemist and druggist who has had six previous
grants. (Redhill.)
A former Associate (79) who has had six previous grants. (Croydon.)
The widow (72) of a chemist and druggist who has had ten previous grants.
(Birmingham.)
The widow (51) of a chemist and druggist and subscriber. She had a grant
last year ; depends chiefly on the charity of neighbours, but tries to earn a little
money by her own exertions. (Morecambe.)
The widow (77) of a registered chemist and druggist, and subscriber. The late
husband had several grants ; she lives in an almshouse, and has 5s. a week.
(King’s Lynn.)
The Committee declined to entertain one application, and to re-open another,
which was considered in October last.
Mr. Bottle (as Chairman of the” Committee), in moving the
adoption of the report, said the cases were all of the ordinary
character, and it was not necessary to detain the Council with
any comments on them. He wished particularly to call the atten¬
tion of his fellow- members on the Council and the public generally
to two very deserving cases of applicants for admission to the
Infant Orphan Asylum at Wanstead. The children he referred to
were Walter Percy Buck, aged 2J years, and Robert Kirby, aged 5J
years, both of them the children of chemists. In his opinion both were
deserving cases, and he should be very glad if any assistance could
be rendered by the Council and their friends by means of the Press.
The resolution passed unanimously.
. been
received,
including the fol-
Total.
Highest.
Lowest. Average.
. 431
23
9
16
. 141
13
0
6
Town.
Country.
Carriage paid.
129
116
£1 8s. 9 \d.
Library, Museum, School, and House Committee.
Library.
The Librarian’s report hf
lowing particulars : —
Attendance.
March . { Evening ’. '. ’. ’. .... 141
Circulation of Books. Total.
March . . 245
Donations to the Library had been announced (Pharm. Journ.,
May 1, p. 372), and the Committee had directed that the
usual letters of thanks be sent to the respective donors.
The Committee had recommended that the following works be
purchased for the Library in London :: —
Tilden, Manual of Chemistry, 1897.
Murray, Flora of Somerset, 1896.
Museum.
The Curator’s report had been received, and included the fol¬
lowing particulars —
Attendance. Total. Highest. Lowest. Average.
A„rfi /^y . 774 54 19 28
Apm . (Evening . 57 6 1 2
Several donations had been received (Pharm. Journ., May
1, p. 372), and the Committee had directed that the usual letters
of thanks be sent to the respective donors.
Miscellaneous.
On the application of Professor Collie, four chemical balances
had been ordered for use in the School.
The draft Annual Report had been discussed, amended, and
referred to the Council for approval.
The Committee recommended that an application from Mr.
R. M. Stearn, a pharmaceutical chemist, for permission to work in
the Research Laboratory be acceded to.
394
PHARMACEUTICAL journal.
[May 8, 1897
The President, in moving the adoption of the report, said there
was nothing special to call attention to.
The report was agreed to unanimously.
Appointment of a Divisional Secretary.
Mr. C. Collen, of St. John’s Hill, Clapham Junction, was
appointed Divisional Secretary for the Parliamentary division of
Battersea in succession to Mr. E. J. Bull, who had removed from
the division.
Correspondence.
The President read a letter from the Assistant-Secretary in
Edinburgh, enclosing the following resolution which was passed
unanimously at a meeting of the Executive of the North British
Branch on April 23 : —
“ That all chemists and druggists should be eligible as members of the Phar
maceutical Society, and that steps should be taken to secure a short Amend-
meat Act to effect this object.”
He suggested that this resolution should be referred to the Law
and Parliamentary Committee.
This was at once agreed to.
Report of Examinations.
April, 1897.
Candidates.
Examined. Passed.
England and Wales : —
Major . 32 20
Minor . 235 7o
Scotland : —
Major . 5 1
Minor . 180 51
First Examination.
Thirty-eight’ certificates by approved examining bodies were
received in lieu of the Society’s examination.
General Purposes Committee.
The Council went into Committee to consider the report of this
Committee, which included the usual letter from the solicitors.
On resuming, the report and recommendations were received
and adopted, and special resolutions were also passed authorising
the Registrar to take proceedings against certain persons named.
The Council then went into Committee to consider the annual
report. After certain verbal amendments it was resolved —
‘ 1 That the annual report and financial statement as now agreed to be published
in the Pharmaceiitical Journal ” (vide p. 387-8).
Failed.
12
160
4
129
PROCEEDINGS UNDER THE PHARMACY ACTS-
CASE AT HAMILTON.
Sale of Poison by an Unregistered Person.
On Thursday, April 29, 1897, at the Sheriff Court House, Hamil'
ton, before Sheriff Mair, Robert Alexander Wright was charged
at the instance of Richard Bremridge, Registrar under the Phar¬
macy Acts, 1852 and 1868, with two offences for selling, in the shop
of the Hamilton Apothecaries’ Co., 38, Cadzow Street, Hamilton,
on Tuesday, November 3, 1896, a quantity of chloroform and a
quantity of cantharides to an agent of the Registrar.
Mr. Loudon, solicitor, Hamilton, instructed by P. Morison,
S.S.C., Edinburgh, appeared for the prosecutor, and Mr. Hay,
solicitor, Hamilton, for the defender, who pleaded guilty to both
offences.
Mr. Hay said this was one of those cases of which his Lordship
had had a number recently, in which the Pharmaceutical Society
had prosecuted assistants in doctors’ Shops. This was a very
simple case. Mr. Wright was very well known in Hamilton, where
he had resided for about fourteen years, and for the last ten years
he had kept this doctor’s shop. One of the Society’s officers entered
the shop and presented to defender a duly initialled doctor’s pre¬
scription for a mixture which contained chloroform. He believed
that in this case it was chloroform water, which was a very
harmless preparation , and no harm would have been done to any¬
body, even if the whole bottleful had been swallowed, He sub’
mitted that this was not one of the cases in which the Pharmacy
Act was intended to apply at all. It was intended to apply to
the promiscuous sale of poisons to children, or in cases where they
were likely to be put to improper uses. There was no suggestion
that this preparation could be put to any improper use ; still, of
course, it contained chloroform, and he supposed the law had
to be vindicated, and the Society must have their con¬
viction. With regard to the cantharides, this was not
made by the defender at all. It was a put-up thing,
and defender could sell it just as well as any qualified
chemist. There was this also to be said, that this offence was npt
likely to occur again. The defender had become so disgusted with
the business of a chemist and druggist that he had retired from it
since this complaint was brought against him, and he intended to
go into some other business. There could be no reason either for
a large penalty from a punitive point of view, as it was not alleged
that any harm had arisen from this sale to any one. He therefore
submitted that only a nominal penalty should be imposed.
Mr. Loudon said he could not admit the statements made for
defender, which would have been disproved if the case had gone to
trial. The mixture did not contain chloroform water but spirit of
chloroform, and the quantity was three times the maximum dose
stated in the British Pharmacopoeia. In the case of the cantharides
it also was made up by the defender from the same prescription as
that from which the mixture was made.
Mr. Hay : He only spread it. He did not make it.
Mr. Loudon : He dispensed the prescription. In the blister the
cantharides was mixed with a fatty basis, and was in such a con¬
dition that it could be directly used for criminal purposes. These
were, moreover, very deliberate offences to which the defender had
pleaded guilty. He had committed them in wilful and persistent
defiance of a very distinct warning from the Registrar so long ago
as March 8, 1888, when there was sent to him the following letter : —
“ I have to inform you that the correspondence and other papers
respecting your registration as a chemist and druggist under the
Pharmacy Act, 1868, were submitted to the Council at its meeting
yesterday in conformity with the provisions set forth under
Section 12 of the Statute. After full consideration, the
Council has instructed and authorised me to remove
your name from the Register of Chemists and Drug¬
gists. I have also to direct your attention to the fact that,
as you are no longer registered as a chemist and druggist, you
become liable to and will be proceeded against in regard to the
penalties set forth in Section 15 of the Pharmacy Act, 1868, if,
after this notice, you continue to carry on the business of a
chemist and druggist, or if you continue using any name implying
that you are registered under that Act.” Defender had also acted in
disregard of the admonition of Sheriff Birnie, before whom he was
convicted in that court on July 9, 1888, of two offences for selling
laudanum.
The Sheriff' : But that warning refers to the carrying on of the
business of a chemist and druggist. He has not been doing that.
He has acted as an assistant to this doctor. Who is the doctor to
whom you act as assistant ?
Defender : Dr. Lennox.
The Sheriff : He was carrying on the business himself when he
was last before the Court.
Mr. Loudon : No, my Lord. I have a verbatim report of the
trial here, and Dr. Lennox appeared on that occasion as the
proprietor of the business which is carried on under the name of
the Hamilton Apothecaries’ Co., and the circumstances were
exactly the same as now. He apparently has been conducting this
business all along, and when he sells poisons he acts as a chemist
and druggist, and carries on the business of a chemist and
druggist.
The Sheriff : That may be so in one aspect of it, but I do not
think that is what is referred to in the warning. He is an
assistant to Dr. Lennox. Has Mr. Hill ever prosecuted any of the
unqualified assistants in chemist shops ?
Mr. Hill : Yes, my Lord, several.
The Sheriff : Well, I have never heard of them.
Mr. Loudon : At any rate the defender was convicted of two
offences for selling poisons in this Court about ten years ago, and I
have to ask that the penalties be imposed now as provided by the
Act.
Mr. Hay : There is no provision in the Act for former penalties
being taken account of.
The Sheriff : Five shillings, and five shillings of costs.
Mr. Loudon : That is five shillings for each offence ?
May 8, 1897]
PHARMACEUTICAL JOURNAL.
395
The Sheriff : No, no ; half-a-crown for each offence, and five
shillings of expenses.
CASES AT GLASGOW.
At the Sheriff Court House, Glasgow, on Friday, April 30, 1897,
a number of cases came before Sheriff Fyfe at the instance of
Richard Bremridge, Registrar under the Pharmacy Acts, 1852 and
1868.
Mr. James Barrie, writer, Glasgow, instructed by Mr. P.
M orison, S.S.C. , Edinburgh, appeared for the prosecutor.
The first case was that of William Forrester, assistant in the
shop of Dr. Robertson, 443, Eglinton Street, Glasgow, who was
charged with selling laudanum on November 21, 1896, to an agent
of the Registrar.
Accused pleaded guilty, and in reply to the Sheriff, said he had
nothing to say for himself, and he was quite aware that he must
be duly qualified before selling poisons.
Mr. Barrie said that in September, 1892, two unqualified
assistants were convicted for selling laudanum, oxalic acid and
red precipitate in this shop, and it seemed evident that there was
an intention to go on in defiance of the law.
The Sheriff : Is there no means of getting at the doctor ?
Mr. Barrie : Unfortunately there is not. They employ
unqualified assistants and allow them to sell poisons without
incurring any penalties themselves. In some cases the penalties
are paid by the doctor but in most instances they leave the
assistants to pay.
The Sheriff : The penalty will be £1 with £2 of expenses.
The next case was against John Campbell, assistant in the shop
of Dr. Dunning, 75, Nelson Street, Glasgow, who was charged
with two offences for selling laudanum and Powell’s balsam of
aniseed to agents of the Registrar on November 28, 1896.
Mr. Gemmel, solicitor, appeared for the defender, who pleaded
not guilty.
Mr. Gemmel objected to the complaint, on the ground that it
charged an offence committed on November 28, 1896. He quoted
the case of Bremridge v. Lyons at Bow County Court in March
last, when Judge French dismissed a case because a month had
elapsed between the offence and the bringing of the charge.
Mr. Barrie said there had been no undue delay on the part of
the prosecutor. Great difficulty had been experienced in getting
the correct names of the offenders in several of these cases, and
they got no assistance from the parties charged. Besides, this
objection had nothing to do with the relevancy.
The Sheriff : The Act provides that a charge may be brought
within six months. I am afraid I cannot accept Judge French as
an authority on procedure. I repel the objection.
Mr. Gemmel said he also objected to two charges when there
was really only one sale of poison. He quoted a case under the
Apothecaries Act, in which it was held that several acts consti¬
tuted but one offence in a charge of acting as an apothecary.
Mr. Barrie pointed out that two different articles were sold to
two separate purchasers, and that was clearly two offences.
The Sheriff upheld this view and repelled the objection.
Mr. J. Rutherford Hill proved that defender was not registered,
and that the articles sold were statutory poisons. In cross-
examination, he stated that it had been impossible to get the
correct name of the offender till about six weeks ago, and the pro¬
ceedings were authorised at the last meeting of Council. Inquiries
were made as to the name on the day the poisons were purchased,
and had been continued ever since till successful.
Alexander Spence and Joseph Tait proved the sales of poison.
For the defence John Steel, assistant in Dr. Dunning’s shop,
appeared, and stated that the doctor’s orders were that no poisons
should be sold when the doctor was not present. Cross-examined,
witness said Dr. Dunning had two shops and three assistants, and
none of them were qualified. The doctor was only in at his con¬
sulting hours, and during the rest of the day there was no qualified
person in either of the shops. If anyone asked for laudanum or
Powell’s balsam when the doctor was not in they would not sell
them.
By the Sheriff : He was not in the shop when these poisons were
sold. He would just be leaving the other shop, and the accused
would be alone in the shop.
The Sheriff : Do you mean to say that for a common article like
Powell’s balsam you would refuse to sell if the doctor was not in ?
Witness : Yes ; we would refuse.
The Sheriff : Of course you mean that the doctor is in the shop
superintending. It would never do for the doctor to be in the
consulting room and you to look round the corner and say “I have
a request for Powell’s balsam,” and he to reply, “That is all
right.” That would not be superintendence at all.
Mr. Gemmel said the accused had no recollection of this matter
at all, and did not remember seeing the Registrar’s agents in the
shop. He had proved the rule of the shop in regard to sales of
poisons, and that rule was always adhered to. He also maintained
that no proper evidence had been adduced to prove that accused
was not registered. The Register produced was for 1896, and the
latest Register was 1897, and it ought also to have been produced.
It lay with the prosecutor to show that accused was' not regis¬
tered.
The Sheriff : The offence was in 1896, and the Act makes the
Register adequate evidence. It lies with you to produce other
evidence that accused is registered.
Mr. Gemmel repeated his objection, founded on the English
decision already quoted. It was also to be noted that this was
not a bona-fide sale, but a purchase for the Society. He held
chat the prosecution had failed, or that in any case a merely
nominal penalty should be imposed so as to teach the Society
to pay better attention in bringing these charges.
The Sheriff said the accused had had all the benefit of a skilful
and ingenious defence by his agent. But unfortunately none of the
points raised were new, and all of them had been disposed of in
the numerous cases and decisions in the Court of Session, and in
England under these Acts. He quite conceived that it was an
unfortunate thing that the defender here should be prosecuted, bub
they could not get at the doctors when it was the assistants who
made the sales. As he had said before, he was not by any means very
greatly impressed with the fairness with which these prosecutions
were gone about, especially the way in which the purchases were
made. He thought it would be more reasonable and more fair to
the respondents if they were treated in the same way as respondents
in adulterated milk cases. When the officers or inspectors bought
the milk they invariably informed the people that it was bought
for the purpose of analysis with a view to prosecution. It was a
little unfair that, at a distance of five months, a man should be
expected to lead evidence as to the circumstances attending the
sale of a pennyworth of laudanum. He could not give the defender
the benefit of this, however, as the Act had laid it down that it
was sufficient if the prosecution was brought within six months,
and there was no doubt that this case was properly brought. As
to the technical objection that only one offence had been committed,
he could not accept the argument for the defence. There coiild be
no doubt that there were two sales of poison. He could not give
defender the benefit of the fact that both were sold at one time in
so far as finding the charges proved was concerned, bub he could
take that into consideration in fixing the penalties. He hoped the
doctor would see that the penalty was paid in this case, for he did
not think doctors who allowed their unqualified assistants to sell
these poisons should leave them to pay the penalties. He would
restrict the penalties to 10s. for each offence and £2 of expenses.
The next case was against John Hendry, assistant in the shop of
Dr. Dunning, at 383, Cumberland Street, Glasgow, who was
charged with selling laudanum and Powell’s balsam to an agent of
the Registrar on November 21, 1896.
The Officer of Court having called the name, no one appeared.
Mr. Barrie : Call for Mr. Hendry.
Mr. Gemmel : You must call the name on the complaint.
Mr. Barrie : Are you appearing in this case ?
Mr. Gemmel : No ; There is an assistant in this shop named
Hendry, but John is not his name and he is nob here.
Mr. "Hill pointed out, sitting in Court, the person believed to be
Hendry.
Mr. Gemmel : This person has two names but neither of them
is John. There is a John Hendry here (this person then advanced
to the bar).
Mr. Barrie : Are you John Hendry, 383, Cumberland Street.
John Hendry : No.
Mr. Barrie : Then why are you here ? You are not wanted.
Mr. Barrie : This case lets your Lordship see the difficulties we
have to meet in these cases. "The parties absolutely refuse to give
their names, and we have accepted the only name we could get. I
now propose to take advantage of Section 7 of the Summary
Procedure Act, 1874, and will proceed to prove the charges an d
take decree in absence of the defender.
396
PHARMACEUTICAL JOURNAL.
[May 8, 1897.
The Sheriff ruled that this procedure was competent.
Matthew Gilmour, Sheriff’s Officer, deponed that he served the
complaint at 383, Cumberland Street. He recognised the person
in Court, who said he was Hendry, and when asked if he was John
Hendry, assented, and accepted service of the complaint. After
reading it he said his name was not John.
At this stage Mr. Gemmel advanced to the bar and said he was
instructed to say that the person who had been pointed out by the
Sheriffs Officer, and who was an assistant in the shop at 383,
Cumberland Street, was named Alexander Wilson Hendry.
Mr. Barrie : Having got this information I now allow this
complaint to drop. We shall serve a new complaint on the person
whose name has at last been given.
The next case was against Minnie Beattie, said to be an assist¬
ant in the shop of Dr. MacDonald, 282, Cumberland Street,
Glasgow, who was charged with selling laudanum to an agent of
the Registrar on November 21, 1896.
On the officer calling the name no one appeared.
Mr. Barrie said they had been refused the name in this case,
and were informed that it was Minnie Beattie, and he intended to
prove the charge and ask decree in absence.
The Sheriff : I will give you an adjournment if you like. There
may be a mistake in the name. If you like, I will grant a warrant
for her arrest.
Mr. Barrie : We would rather not go to that extreme just now.
I will prove service of the complaint and then ask another diet to
be fixed.
Matthew Gilmour, Sheriffs Officer, and his assistant, Peter
Ferguson Ramsay, proved that the complaint was duly served on
the young woman, who acts as assistant to Dr. Macdonald, and she
accepted service.
The Sheriff : Then I adjourn this case till Monday, May 17, at
2.30, and order intimation to be made to the defender. You may
tell her that had you asked warrant for her arrest I should at once
have granted it, and that if she does not appear at the adjourned
diet the consequences may be serious.
Another case had to be abandoned because the defender had
disappeared and could not be traced.
NOTES AND FORMULAS.
Moustache Fixing Fluid.
Balsam of Tolu . . . 1 part
Rectified Spirit . . . 3 fluid parts
Jockey Club . . . . . 1 fluid part
Dissolve the balsam in the mixture. Put up in small bottles with
a brush attached to cork. Directions : Apply a few drops to the
moustache with the brush, then twist into the desired shape.
LITERARY NOTES.
‘ Dental Surgery for Medical Practitioners and Students of
Medicine,’ by A. W. Barrett, M.B., etc., is the third issue of
thab useful little work, and it is in many ways far ahead
of previous editions. The book is written in such a manner
as will insure its proving a handy and reliable guide to
medical practitioners, and deals with the following subjects : —
The Teeth Generally ; the First Dentition ; the Second Dentition ;
Abnormalities in Development of Permanent Teeth ; Irregularity
in the Positions of Permanent Teeth ; Dental Caries ;
Toothache ; Tartar ; Pyorrhoea Alveolaris ; Absorption of Alveolar
Process ; Injuries to the Teeth ; Preparation of the Mouth for and
the Wearing of Artificial Teeth ; Anaesthetics, General and
Local : Fractures of the Maxillae ; Extraction of the Teeth.
It is to be hoped that in subsequent editions the author will
devote some attention to those subjects where the pathological
conditions so frequently arise from dental conlplications, such as
empycema of the antrum, dentigerous cysts, etc., which appear to
be more suitable for medical men than the articles included in
Chapter 10, which belong more to the province of the dental than
the general practitioner. The illustrations are numerous and
good, and help materially to explain the author’s meaning. The
book is certainly greatly in advance of many other works on the
same subjects. It is published at 3s. 6 d. by H. K. Lewis,
136, Gower Street, W.C.
‘Extraction of the Teeth,’ by J. F. Colyer, L.R.C.P.,
M.R.C.S., L.D.S., is a valuable little work, written in a clear and
practical manner, dealing with : The General Principles of Extraction
of the Teeth ; The Extraction of Individual Teeth ; The Extrac¬
tion of Misplaced Teeth ; The Use of Anaesthetics during
Extraction of the Teeth ; Difficulties, Complications, and Sequelae
of Extraction of the Teeth. There is a carefully arranged index,
and the book will be useful alike to dental practitioners and
students, who will findthat most of the difficulties and complications
met with in extracting teeth are carefully and explicitly dealt with,
as well as the most expeditious and modern ways of overcoming
them. The author apparently writes with an extensive experience,
aided by careful observation. A perusal of the work will well
repay all those engaged in dental surgery, and who realise how
important it is to be a skilful tooth extractor. The many illustra¬
tions are carefully introduced, and form a valuable part of the
work. The printing and binding are excellent, and the book is
published in a very convenient form, at 3 s. nett, by Claudius, Ash
and Sons, Broad Street, Golden Square, W.
Freezing Mixture.
Washing soda .
Ammonium nitrate
| equal parts
Crush the soda to coarse powder immediately before required
for use ; then mix with the ammonium nitrate without adding any
water. This will give a temperature of - 18° C. A flannel wrapped
round the containing vessel will “ keep the cold in.”
Agar Agar Gelatin.
Japanese gelatin, 6; glycerin, 60; boric acid, 10; essence
jasmine, 10 ; water, q.s. , ad. 1000. Dissolve the boric acid and glycerin
in the water and add solution to gelatin contained in a suitable
vessel. Heat until solution is effected. Perfume with essence of
jasmine and fill into collapsible tubes.— American Drug., xxix., 393.
Manufacture of Rubber Plasters.
Para rubber is first purified after being softened in boiling water,
by being washed with water in a disintegrator, then dried on cloths.
The plaster basis, such as resin wax, is melted and strained, the
medicament is added and then the rubber. The whole is then
passed through heavy hot steel rollers until an intimate mixture
results, a certain proportion of powdered orris root being added
during this process to destroy the stringy consistence of the rubber.
The mass is next spread on the cloth by means of a machine similar
to that employed in paper making, consisting of three heavy steel
rollers. This plant must be firmly fixed as the least vibration
interferes with the evenness of the plaster. — Pharm. Zeit., xli., 344.
‘The Year Book of Photography’ for 1897 is an exceptionally
useful guide for the amateur photographer. The first section,
entitled “ Progress and Practice,” consists of a collection of help¬
ful articles by practical photographers. In the first the Editor,
Mr. E. J. Wall, F.R.P.S., treats of elementary optics, with
special reference to photographic lenses. The subject is treated
in plain and simple language, without the use of mathematics, and
illustrations are freely employed. Development and developers
are exhaustively discussed in the next article, and then come
hints on silver printing, by J. A. Randall. Section two contains
an exposure table, a table of solubilities, and numerous useful facts
and formulae ; section three is a capital holiday guide for photo¬
graphic tourists, in which particulars are given concerning most
places of interest in the United Kingdom ; section four is a
practical instruction book for the amateur slide worker, and includes
an article on “Radiography with the Wimshurst,” by S. R. Bottone ;
whilst section five is a complete descriptive guide to the latest
novelties in photographic apparatus and materials. The book is
published at the Photographic Neivs Office, 22, Furnival Street,
E.C., at the marvellously low price of one shilling.
‘ The Chronicles of Christopher Bates,’ by Mr. Ebenezer
Rees, is published by The Roxburghe Press, 15, Victoria Street,
Westminster, at 3s. 6 d. This fact should have been stated last
week when reference was made to the work. The book is
excellently printed, and tastefully bound in art canvas.
May 8, 1897]
PHARMACEUTICAL JOURNAL.
397
Pharmaceutical Journal.
ESTABLISHED 1841.
Circulating In the United Kingdom, France, Germany,
Austria, Italy, Russia, Switzerland, Canada, the
United States, South America, India,
Australasia, South Africa, etc.
Editorial Office : 17, BLOOMSBURY SQUARE, W.C.
Publishing atld Advertising Office : 5, SERLE STREET, W.C.
LONDON: SATURDAY, MAY 8, 1897.
THE COUNCIL MEETING.
At the opening of the meeting the President referred to
the forthcoming International Congress at Brussels, and
suggested that the appointment of delegates might
he conveniently deferred until the next meeting of the
Council, in June, when delegates to the British Pharma¬
ceutical Conference, to he held in Glasgow about the same
time, would also be appointed.
Since the last regular meeting, Mr. Earle, of Staines, one
of the founders of the Society, has died, and a vacancy has
been created in the list of honorary members by the death of
Professor Russow, of Dorpat.
The additions to the Society comprised nineteen members,
ninety- six associates, and twenty-five students.
The report of the North British Branch Executive for the
year ending last March showed that although in some
details the current expenses have been less than in the pre¬
ceding year, there has been a considerable nett increase in
connection with the examinations. The number of candi¬
dates for the qualifying examination has been considerably
greater, but the percentage of passes was even less than in
the previous year.
Dr. Symes, in referring to the generally satisfactory nature
of the report, suggested that in connection with the large
percentage of failures in the examinations some information
might be useful as to the particular subjects in which the
candidates failed. The President mentioned that those par¬
ticulars would probably be given in the reports presented by
the Government Visitor to the Privy Council. Past experi¬
ence has shown that failure in the practical subjects of
dispensing, etc., was as frequent as in the more scientific
subjects.
On the motion of the President, seconded by Mr. IIamp-
son, the proposed new bye-laws were taken as read for the
third time and confirmed.
Mr. Bateson expressed satisfaction that the proposed
change in regard to the Preliminary examination has met
with such general approval, and was not surprised to find
that there was not the same unanimity as to the raising of
the fee for the qualifying examination, though the Council
has repeatedly discussed the matter very carefully, and the
proposal has been agreed to more than once without any dissent.
He accounted for the want of unanimity on this point by
referring to the present difficult conditions of the chemist’s
business in some parts of the country, and the consequent
tendency to ask what advantage would result from the
change. But notwithstanding the possibility of some differ¬
ence of opinion on that account, he believed the proposed
increase of the fee to be right and calculated to pro¬
mote the interests of those already members of the
craft, as well as the interests of those about to become so.
He should, therefore, conscientiously support the pro¬
posal on its merits and without being influenced by the
opinion of any of his colleagues. He repudiated the sugges¬
tion that the raising of the fee was intended to bolster up
the finances of the Pharmaceutical Society, and referred to
the financial statement then before the Council as a sufficient
refutation of that idea. In view of the work that the
Society will have to do in the future, he believed that these
new bye-laws would have the effect of consolidating the
craft and uniting its members more closely as one corporate
body, besides furnishing the Council with the- necessary
assistance in its efforts.
The chief feature of interest in the report of the Finance
Committee was the announcement that the late Mr. George
Nind has left a legacy of two thousand pounds to be applied
for the purposes of the Benevolent Fund.
On the recommendation of the Benevolent Fund Com¬
mittee, five grants were ordered to be paid, amounting in the
aggregate to thirty-five pounds. Mr. Bottle, as Chairman
of the Committee, in moving the adoption of the report,
drew attention to two applicants for admission to the Infant
Orphan Asylum, for whom he particularly desired to obtain
support.
Mr. C. Collins wa3 appointed Divisonal Secretary for
Battersea, in succession to Mr. E. J. Bull, who has removed
from the district.
A resolution, passed by the North British Branch Execu¬
tive, that steps should le taken to make all chemists and
druggists eligible as members of the Pharmaceutical Society,
transmitted by the Assistant Secretary, was referred to the
Law and Parliamentary Committee. This will help to
bring about a change which has long been very generally
recognised as desirable.
The recommendation of the General Purposes Committee
that the annual report and financial statement should be
published was agreed to, and the Registrar was authorised to
take proceedings under the Pharmacy Act in certain cases
which had been considered by the Committee.
ELECTION OF MEMBERS OF COUNCIL.
The Secretary of the Proprietary Articles Trade Associa¬
tion has forwarded for publication a letter stating the views
held by members of that body in regard to the trade in pro¬
prietary articles, and giving the general result of correspond¬
ence with the candidates for election as members of the
Council of the Pharmaceutical Society. While disclaiming
any hostility to the Society, Mr. Glyn- Jones’ letter is
intended to be adverse to certain of the candidates and
therefore we must decline to publish it, as it has always been
held that the Pharmaceutical Journal is not the place in
which influence should be exercised upon the election in
reference to matters upon which differences of opinion exist.
398
PHARMACEUTICAL JOURNAL.
[May 8, 1897.
ANNOTATIONS.
The Decennial Festival Dinner in aid of the Benevolent Fund
will be held at the Hotel Cecil, Strand, W.C., on Tuesday, May 18,
and as the time is now short those who have not yet applied for
tickets, or intimated their desire to act as Stewards, should
communicate with the Secretary at once. The dinner will serve
as a ready means of combining personal enjoyment with
benevolence, and in this year of commemoration a special effort
ought to be made by everyone connected with British pharmacy
to prove that the craft is in no degree behind others in matters of
loyalty and charity. As has been suggested on a previous
occasion, those who do not expect to be able to attend the
dinner can yet help in a very marked degree by taking tickets-
Another way in which the Benevolent Fund can now be assisted is
for local secretaries and others connected with the Pharmaceutical
Society to impress upon chemists not so connected the desirability
of supporting a fund which is so catholic in its operation. In this
way, by uniting efforts, it may be possible to establish a record and
facilitate the Society’s work of benevolence in a time of sore need.
The calls upon the Fund are much in excess of what can at present
be accomplished, and it will lastingly redound to the credit of
those who practise pharmacy in Great Britain if it should be
rendered possible, at the close of the year, to say that the amount
received in subscriptions during the twelve months has been greatly
in excess of the expenditure incurred in relieving all suitable cases
where assistance is needed.
At the Annual General Meeting on Wednesday, May 19,
Mr. James Mackenzie will propose : “That this meeting of the
Pharmaceutical Society of Great Britain is satisfied that great
improvements in the constitution, powers, and working of the
Society are required, in order to provide adequate protection to
its Members and Associates, securing also greater protection and
safety to the public.” It resolves therefore : —
“ That until some beneficial change has been effected constitutionally, no
alteration in the bye-laws is called for at the present time."
Notice has also been given by Mr. A. C. Wootton of a motion he
intends to bring forward at the Special General Meeting on the
same date. It is in the following terms : —
“ That for the words ‘11 to 24 of Section 10’ shall be substituted the words
‘ 11 to 16 and IS to 24 of Section 10,’ and that for the new bye-law 17 existing
bye-laws 16 and 17 shall be substituted."
The Difficulty of Administering the Pharmacy Act con¬
tinues to be exemplified in Glasgow, as will appear from the re¬
ports published at page 395. A sufficient answer to the Sheriff s
remarks in Campbell’s case is supplied by the fact that the pro¬
cedure adopted by the Society’s agents is strictly in accordance
with the Statute. It appears that the Sheriff came to the case
fresh from another court, where he had disposed of several milk
cases under the Sale of Food and Drugs Act, but he ought to be
able to appreciate the difference between two totally different
Statutes, and not allow an obviously unfair comparison of methods
of procedure which are far from parallel to influence him. But it
is of greater importance to note how every obstacle is put in the
way of the Society by offenders in Scotland, any artifice being
resorted to as a means of defeating the ends of justice. It is
quite a regular practice, we are informed, for names to be refused
when asked for in connection with these cases, or for false infor¬
mation to be supplied. The result is that, after an enormous
amount of trouble has been taken in the matter and much expense
incurred, cases have to be dropped and fresh complaints served.
All this is done primarily in the public interest, whilst secondarily
in the interests of chemists and druggists, the bulk of whom refuse
to support the Society, and it illustrates the nature of the
“ luxuries ” in which subscribers to the Society are alleged to
indulge themselves.
The Hamilton Case, unfortunately, was heard by Sheriff Mair,
whose decisions on previous occasions have afforded ground for the
suspicion that he is strongly prejudiced against the Pharmaceutical
Society and allows that prejudice to affect his judgments. In the
present instance, as on former occasions, he inflicted a merely
nominal penalty, but this will not deter the Society from proceed¬
ing in all cases where evidence is forthcoming that the Statute
has been infringed. Even Sheriff Mair may be brought to see
reason in time and, whether large penalties or small be imposed,
he can, at any rate, be compelled to convict offenders when they
are proved beyond doubt to be guilty of offences under the Act.
The War in Greece is of direct pharmaceutical interest in its
worst aspect, i. e. , the medical treatment of the wounded. The
natural sympathy felt for the sufferers has found expression in an
appeal by the Daily Chronicle for funds to enable the conductors
of that journal to send out medicines, dressings, instruments,
etc., for use by the Greek forces. Though it is not quite apparent
why wounded Turks should not also share the benefits, but
perhaps because they are by implication excluded from those
benefits, and hysterical persons are apt to think that a Turk
can be a worse specimen of humanity than a Greek,
the response to this appeal has been both prompt and
magnificent in its extent. A sum of several thousand pounds has
been subscribed in a few days, at the rate of a thousand pounds a
day, and numerous firms have promised gratuitous supplies of their
specialties, or have undertaken to supply them at reduced rates.
The Medical and Surgical Arrangements in connection with
the fund are particularly complete, and the prompt manner in
which all the details have been carried out affords striking testi¬
mony of the splendid organisation of one of our leading
hospitals. On the recommendation of Sir William MacCormac,
President of the Royal College of Surgeons, Mr. F. C. Abbott,
Resident Assistant-Surgeon of St. Thomas’s Hospital, has
been appointed Chief Medical Officer, with two assistants, Messrs.
H. J. Davis and R. Fox-Symons, both former members of the
staff of the same hospital. Mr. H. A. Moffat, formerly House-
Surgeon at Guy’s Hospital, also accompanies Mr. Abbott.
Mr. Edmund White, Pharmaceutist to St. Thomas’s Hos¬
pital, and well-known as one of the Pharmaceutical Society’s
examiners, has undertaken the selection and supervision of all the
drugs, chemicals, dressings, bandages, etc., required, and we have
been favoured by him with some interesting facts concerning the
supplies.
Bandages, Lint, Gauze, etc. , are being obtained from Messrs.
Robinson and Sons, Limited, of Chesterfield, and the quantity of
those bulky articles sent may be gauged from the fact that the
total weight to be despatched will be about five tons. Twenty-
four thousand yards of antiseptic gauze, half a ton each
of lint, absorbent cotton-wool, and sublimate wool, five hundred¬
weight of boric lint, seven hundredweight of gamgee tissue, and a
hundred and fifty gross of roller bandages are amongst the stock
sent, besides flannelette, muslin, grey wool for padding splints,
plaster of paris, strapping plaster supplied by Messrs. A. de St.
Dalmas and Co. , of Leicester, and jaconet and waterproof sheeting
supplied by Mr. Albert Browne, of Leicester.
May 8, 1897]
PHARMACEUTICAL JOURNAL.
399
The Drugs and Chemicals have been Ordered from Messrs.
Burgoyne, Burbidges, and Company, to a considerable extent, the
items including three hundredweight of soft paraffin, a hundred¬
weight and a-half of powdered boric acid, a hundredweight of
crystallised carbolic acid, two hundred pounds of chloroform,
and chlorinated lime, glycerin, creolin, magnesium sulphate,
chloral and bromide solution, zinc ointment, boric acid oint¬
ment, coal tar soap, and solution of lead subacetate in corre¬
spondingly large quantities. Other prominent items in the list are
tannic acid, calomel and colocynth pills, iodoform, belladonna,
and iodine liniments, potassium permanganate, strong solution
of ferric chloride, etc., etc.
Compressed and Other Medicaments are being supplied by
Messrs. Allen and Hanburys and Burroughs, Wellcome, and Co.
The former are sending a very large stock of various tabellse —
mercuric chloride, opium, sulphonal, etc. In addition, their
order includes about fifty-six pounds of pills of different kinds, to¬
gether with three gross of mercuric chloride cartridges, and
cachets containing sulphonal, bismuth carbonate, and compound
catechu powder respectively. A comparative novelty is being sent
in the shape of “chrismoids” of carbolic acid and mercuric chloride.
These are hard capsules, which are convenient to use when anti¬
septic solutions are not available.
Three Portable Medicine Chests fitted with feather-weight
containers are being lent by Messrs. Burroughs, Wellcome and Co.,
who are also sending some fifty thousand tabloids of antipyrine,
ammonium carbonate, sodium salicylate, quinine bisulphate, etc.,
in addition to considerably more than two thousand tubes of hypo¬
dermic tabloids, containing cocaine, morphine, and strychnine
sulphate. The medicine chests are supplemented by three dis¬
pensing belts and twelve pocket cases, all fitted with feather¬
weight containers for tabloids.
X Ray Apparatus is prominent in the surgical outfit of this “Red
Cross ” expedition, the apparatus having been selected and tested
by Ur. Barry Blacker, of St. Thomas’s Hospital. It is similar to
the apparatus in daily use at St. Thomas’s Hospital, and consists
of the following items : — A large induction coil for obtaining the
high tension currents for generating the rays in the vacuum
tubes ; a double set of accumulators for supplying the current to
magnetise the iron core of the coil, thus rendering the working of
the rays possible for very many hours in succession ; a sufficient
number of the most efficient type of X ray focus tubes ; a fluores¬
cent screen, capable of showing every joint and bone in the body,
coated with a double layer of platino-cyanide of barium on which
the shadows of the bones and bullets will be cast ; a quantity of
Eastman’s X ray paper, with developing solution capable of taking
five hundred prints, should the operator not have the time at his
command to observe the shadows on the fluorescent screen. The
secondary of the coil is over thirteen miles in length, and will give
a heavy discharge through ten inches of air. It is hoped that it
will be possible to use the fluorescent screen to the exclusion of
the photographic method, as the position of the bullet or the seat
of the injury may be viewed in many positions rapidly, and the
time required to develop a dry plate (although much shortened by
the use of Eastman’s new X ray paper) constitutes a serious delay
to the busy surgeon, especially on the battle-field or in the hospital
after a hard-fought fight.
The Proposed Medical Boycott in the Plymouth district has
been resolved upon , despite a protest made at the meeting that an
attempt was being made to interfere with members of the pro¬
fession doing what was quite legal, and a warning that by at¬
tempting to “ ostracise ” some of their fellows those agreeing
with the motion would be lowering themselves in the eyes of the
public. Moreover, it was pointed out that, whilst some local
practitioners had complained of the abuses of clubs which provide
medical aid, it should not be forgotten that medical men are not
unknown as customers at so-called co-operative stores. Never¬
theless, the original motion was- persisted with, and now twelve
medical practitioners in Plymouth, Devonport and Stone-
house have solemnly decided never more to meet in con¬
sultation any medical officer of the Three Towns Friendly
Societies’ Medical Institution. They have also placed
on record the expression of their opinion that medical
men who take office in the Institution are, by so doing,
lowering the dignity of the profession and placing themselves in a
false position. Encouraged by their partial success, those present
at the meeting decided to advance another step if possible. Accord-
ingly, the meeting was adjourned for a week in order that other
important resolutions might be discussed, including one intended
to prohibit meetingin consultation any practitioner who shall, in the
opinion of the Plymouth Medical Society, be guilty of advertising,
touting, or other irregular practice. Apparently, attempts to
check the wheels of the chariot of progress are not yet entirely
things of the past, but the present one is more calculated to
provoke scorn and ridicule than to produce any good effect.
Dr. Edmund Russow, an honorary member of the Pharma¬
ceutical Society, died on April 11, at the comparatively early age
of fifty-six years. He was Professor of Botany and Director of the
Botanical Gardens at the University of Dorpat. His special de¬
partment of research was anatomical botany, and he had devoted
particular attention to the comparative structure of vascular
bundles. In manner he was most pleasant and genial, and as a
teacher he was much liked. His death is greatly regretted.
The Liebig’s Extract of Meat Company, Limited, has won an
action against Bovril (British, Foreign, and Colonial), Limited,
heard at the Antwerp Tribunal of Commerce, under the presidency
of M. Hertogs. The plaintiffs sought to restrain the defendants
from publishing statements in Belgium, comparing the plaintiffs’
goods unfavourably with those of the defendants. Those state¬
ment plaintiffs contended were untrue, and they claimed damages
and the publication of the judgment. As a result the Tribunal
condemned the Bovril Company and their agent to withdraw from
their prospectuses, advertisements, labels, and posters — within
forty-eight hours from the delivery of judgment — all comparisons
unfavourable to the products of the Liebig Company, and ordered
them to pay to the plaintiffs ten thousand francs damages and costs,
whilst authorising plaintiffs to publish the judgment at the
expense of the defendants in ten Belgian newspapers.
A Dangerous Adulteration of Aniseed is reported by the
Berlin correspondent of the Daily News, who says it has become
known there that three bales of aniseed received at Rotterdam
from Bari, on examination by the Board of Health at The Hague,
revealed the presence of 10 per cent, of hemlock fruits. The
sale of the adulterated aniseed was forbidden in Holland, but
it was sent from Rotterdam to Germany, and efforts to trace
it since have so far failed. Assuming the accuracy of this report, it
will be more than ever desirable for pharmacists to submit any
powdered aniseed they may purchase to strict microscopical
examination, more especially if they have any suspicion that it has
been imported from Germany.
400
PHARMACEUTICAL JOURNAL.
[May 8, 1897
MEETINGS Op SCIENTIFIC SOCIETIES
- ♦ — i —
Chemical Society, Thursday, April 29. — Professor Dewar,
F.R.S., President, in the chair. — There were no authors present
at this meeting to read their papers, consequently the business
was rather uninteresting. The first paper was by Prof. H. B.
Dixon, F.R.S., and S. J. Russell, B.Sc., on —
The Explosion of Chlorine Peroxide with Carbon Monoxide.
It was read in abstract by Mr. Dunstan, and is a continuation of
the work done by the authors on the same subject. — Some rather
interesting points came out in the discussion.— Professor Crookes
referred to the great difficulty of drying gases. With sulphuric
acid, he said, it was an impossibility to bring about complete
desiccation, and even phosphoric anhydride acted imperfectly.
—The President, Professor Armstrong, and Dr. Scott also had
a few words to say on the subject. A paper on —
The Decomposition of Iron Pyrites,
by W. A. Caldecott, B.A., was received by the Society in almost
a spirit of ridicule, but when Mr. Crookes pointed out the
difficulties under which the chemist laboured— he is an Australian
mining chemist — the tone of the meeting changed a good deal.
The last paper, entitled —
Monochlordiparaconic Acid and Some Condensations,
by H. C. Myers, Ph.D., was more an intimation that the author
had taken up the subject than anything else.
Royal Institution, Thursday, April 29. — Professor Dewar
on this occasion gave the first of a course of lectures on—
Liquid Air as an Agent of Research.
He began by remarking that it was a mistake to suppose
that the establishment of the various cryogenic laboratories
that now exist in Europe was due to a desire merely to
attain very low temperatures. The establishment of the
laboratories was rather to investigate the conditions of gases
at all temperatures, and thus carry on the work of Faraday,
Regnault, and Dr. Andrews, of Belfast. The laws of Boyle
and Charles, connecting together the volume, pressure, and
temperature of a gas broke down before the liquid state was
reached. Van der Waals, working on the careful measurements
made by Andrews, proposed for them a new formula by which
the gaseous and liquid states were connected. From this formula
it was possible to calculate the critical temperature of a gas, above
which no amount of pressure could liquefy it, and the work of
Cailletet and others consisted in the experimental verification of
the results thus obtained. Van 'der Waals also predicted that
there would be found one isothermal line which would express the
pressure, temperature, and volume relations of all gases, and this
prediction was confirmed by the work of Amagat. Coming to the
difficulty of getting to very low temperatures, Professor Dewar
said that if liquid hydrogen could be had to-morrow, the zero of
absolute temperature would still be a long way from being
attained, and there would be no conceivable way of reaching it.
No liquefied gas could be utilised to produce a fall of
temperature more than one-third to one-half its absolute
critical range, hence the lowest temperature that could be obtained
by means of liquid hydrogen would still leave some twenty degrees
aoove the absolute zero. Professor Dewar then proceeded with a
number of experiments which illustrated the application of extreme
cold to the purposes of analysis, by showing how such compounds
as ethylene and marsh-gas by its aid could be separated out in a
liquid form from a mixture like coal-gas. He also showed the
extreme contraction produced by cold in gaseous and other bodies
by cooling one end of a tube full of ethylene, the other end being
immersed in mercury. When the ethylene became liquid the
mercury was seen to have risen in the tube substantially as high
as in the barometer, thus proving the vapour pressure to be
practically as small as in the Torricellian vacuum.
Royal Institution, May 1. — Sir James Crichton-Browne,
M.D., F.R.S., Treasurer and Vice-President, in the chair. — This
was the annual meeting of the members, and the annual report of
the Committee of Visitors for the year 1896, testifying to the con¬
tinued prosperity and efficient management of the Institution, was
read and adopted. Fifty-eight new members were elected in 1896.
Sixty -four lectures and nineteen evening discourses were delivered
in 1896. The books and pamphlets presented in 1896 amounted to
about 274 volumes, making, with 621 volumes (including periodicals
bound) purchased by the managers, a total of 895 volumes added
to the library in the year. Thanks were voted to the President,
Treasurer, and the Honorary Secretary, to the Committees of
Managers and Visitors, and to the Professors, for their valuable
services to the Institution during the past year. The following
gentlemen were unanimously elected as officers for the
ensuing year : — President, The Duke of Northumberland,
K.G.,D.C.L., LL.D. ; Treasurer, Sir James Crichton-Browne, M.D.,
LL.D., F.R.S. ; Secretary, Sir Frederick Bramwell, Bart., D.C.L.,
LL.D., F.R.S., M.Inst.C.E. ; Managers, Sir Frederick Abel,
Bart., KC.B., D.C.L., LL.D., F.R.S, the Right Hon. Arthur
James Balfour, M.P., D.C.L., LL.D., F.R.S., John Wolfe Barry,
Esq., C.B., F.R.S., M.Inst.C.E., William Crookes, Esq., Edward
Frankland, Esq., D.C.L., LL.D., F.R.S., Charles Hawksley, Esq.,
M.Inst.C.E., Donald William Charles Hood, M.D., F.R.C.P.,
Victor Horsley, Esq., M.B., F.R.S., F.R.C.S., William Huggings,
Esq., D.C.L., LL.D., F.R. S., the Right Hon. Lord Lister, M.D.,
D.C.L., LL.D., Pres. R.S., Ludwig Mond, Esq., Ph.D., F.R.S.,
Arthur William Riicker, Esq., M.A., D.Sc., F.R.S., Basil Woodd
Smith, Esq., F.R.A.S., F.S.A., the Hon. Sir James Stirling,
M.A., LL.D., Sir Henry Thompson, F.R.C.S., F.R.A.S. ; Visitors,
Sir James Blyth, Bart., William Arthur Brailey, M.D.,
M.R.C.S., Edward Dent, Esq., John Ambrose Fleming, Esq.,
M.A., D.Sc., F.R.S., Edward Kraftmeier, Esq., Sir Francis
Laking, M.D., Hugh Leonard, Esq., M.Inst.C.E., Sir Philip
Magnus, J.P., T. Lambert Mears, Esq., M.A., LL.D., Lachlan
Mackintosh Rate, Esq., M.A., Thomas Tyrer, Esq., F.C.S., F.I.C.,
Roger William Wallace, Esq., Q.C., John Westlake, Esq., Q.C.,
LL.D., His Honour Judge Frederick Meadows White, Q.C.,
James Wimshurst, Esq.
Linnean Society of London, Thursday, April 15. — Dr. A.
Gunther, F.R.S., President, in the chair. — Mr. W. B. Hemsley
was admitted and Mr. Daniel A. Jones was elected a Fellow of the
Society. — Mr. H. Fisher, the naturalist attached to the Jackson-
Harmsworth Polar Expedition, gave some preliminary observa¬
tions on the plants collected by him during his two years’ resi¬
dence on Franz- Josef Land. — On behalf of Mr. A. O. Walker an
abstract was read of a paper on —
Some New Crustacea from the Irish Seas.
Of the four species of Edriophthalma described as new, two of
them, viz. , Leuconopsis ensifer and Stenothoe cras-sicornis, were taken
at a depth of thirty-three and twenty-three fathoms respectively
during the dredging and trawling operations of the Liverpool
Marine Biological Committee, in April, 1896, in the steamer “John
Fell,” which was then employed in obtaining ova for the experi¬
mental fish-hatchery at Port Erin. It was found that by attaching
a tow-net with a light cane ring to the back of the trawl-net a short
distance behind the foot-rope, many small Crustacea were cap¬
tured, including the above-named species. Of the other two
novelties, Apseudes hibernicxis was taken by Mr. Gamble between
tide-marks during a week’s collecting at Valentia Harbour, and
Parapleustes latipes was found by Mr. Walker while naming
the collection of Amphipoda in the Dublin Museum of Science and
Art. Four specimens were taken in 750 fathoms off the S.W. coast
of Ireland. Until the publication of the Report of the Committee
on the Marine Zoology of the Irish Sea (‘Brit. Assoc. Report,’ 1896,
pp. 417-450), very little had been done in investigating the Edrio-
phthalma, except in the neighbourhood of the Isle of Man, where
Mr. Walker had collected a large number of species, as noticed in
the above-mentioned report. — The Secretary then gave an ab¬
stract of a paper by Dr. A. J. Ewart — -
On the Evolution of Oxygen from Coloured Bacteria.
The author found that coloured bacteria under certain appropriate
conditions possess the power of evolving oxygen in greater or less
amount. In some the oxygen appeared to be absorbed from the air
by the pigment substance excreted by the bacteria. The process,
he considered, was not a vital one. The substances contained in
an alcoholic extract were found to have the same power, though
less marked, of occluding oxygen,' but this property was soon lost.
The purple and green bacteria, in which the pigment forms an
integral part of the bacterial plasma, when exposed to radiant
energy, showed a very weak evolution of oxygen, continuing for
an indefinite period under favourable conditions. In the former of
these the assimilatory “pigment” is “ bacterio-purpurin,” in the
latter “chlorophyll.” The process in this case is a vital one, and
the oxygen evolved is apparently derived from the assimilation of
carbon dioxide. — A paper by Messrs. W. and G. S. West on
‘ * Desmids from Singapore ” was deferred.
Mav 8, 1897]
PHARMACEUTICAL JOUItXAL.
401
THE WORLD OR PRHRlVIflCY.
— —
BUSINESS MEETINGS.
Bristol Pharmaceutical Association, Wednesday,
April 28.— Mr. Allen, President, in the chair.— It was unani¬
mously resolved that a donation of £5 5s. from the funds of the
Association be given the
Benevolent Fund of the Pharmaceutical Society.
The question of special rates for the carriage of small parcels
was then referred to by Mr. Plumley, who called attention to the
rates charged by the various parcel companies for
Small Parcels from London.
and said that the Plymouth chemists had obtained a much lower
contract than that existing in Bristol. Mr. Plumley said he had
approached all the carriers, but had failed so far in getting better
terms. — Mr. Plumley was thanked for his efforts and requested to
continue his negotiations.
The Proposed New Bye-Laws.
In connection with this subject, Mr. J. W. White proposed the
following resolution : —
“ That this Association desires to express its approval of the new bye-laws
proposed by the Council of the Pharmaceutical Society.”
Mr. White explained that the proposed alteration related chiefly to
two matters — first, the abolition of the existing Preliminary exam¬
ination and the substitution of some recognised school examination ;
secondly, the increase of the fees payable on the qualifying exami¬
nation to £10 10s. As to the first, it was a subject long talked of,
and a step in the right direction, because the effect of the alteration
would be to exclude the ill-educated youths who now came up time
after time, with the inevitable consequence of a large number of
failures. He hoped this step would secure youths from a better class,
thus ensuring more hope of success in succeeding examinations. With
reference to the other matter, the Society no doubt wanted money,
and the Council naturally turned in that direction. There seemed
to be no means of economising but by abandoning the Journal
or the educational work of the Society, and it was impossible
seriously to consider either of those plans. He understood
that owing to repeated failures the average fee now paid by
each candidate was £8, therefore the increase was more ap¬
parent than real. The change would be good if it were the
means of ensuring candidates coming up better prepared than
at present.- — Mr. B. Keen seconded the motion, referring to the
unanimous way in which the proposals had been agreed to by the
Council of the Society, as well as the uniformity with which
provincial associations had supported them, the only note of
criticism coming from the Editor of the Chemist and Druggist.
Mr. Keen thought the Editor saw in the Pharmaceutical Journal a
formidable competitor, though he questioned whether the Editor
was wise, even in his own interests, for Mr. Keen had heard it
suggested by readers of the C. and D. that steps should be taken
to inform the Editor that the opinions he had expressed were not
those held by most members of the trade. Mr. Keen quoted the
statistics published in the Pharmaceutical Journal of March 20,
showing that the publication was no such burden upon the Society
as had been represented. The speaker also said that the fee to be
increased was really a registration fee, and the Society had not
done with a student when he had been examined and placed on
the Register. The Register had to be kept and corrected from
time to time, and if the individual did not join the Society, the
expenses of his registration, however long he lived, were borne by
the members of the Society. That was most unfair, for he was
really reaping an advantage which others had to pay for.
An Amendment That Failed.
Mr. Pitciiford proposed as an amendment —
That while approving of the alteration in the Preliminary examination, the
increased fee for the Minor is altogether unwarranted."
He explained that he was quite out of sympathy with the Phar¬
maceutical Society for a variety of reasons, and thought the in¬
creased fee was really intended to provide means of unfair
competition with trade journals. The amendment was not
seconded, however, and the original resolution was carried by a
large majority. — Before the meeting closed, the Honorary Secretary
called attention to the forthcoming
Election of the Council
of the Pharmaceutical Society, and pointed out the desirability of
having a larger proportion of London members elected.
Oxford and District Chemists’ Association, Friday,
April 30. — Mr. G-. Claridge Druce, President, in the chair. — This
was the inaugural meeting of the Association, and amongst those
assembled at the Clarendon Hotel, Oxford, were Mr. Walter Hills,
President of the Pharmaceutical Society, and Mr. R. Bremridge,
Secretary of the Society ; Messrs. C. Clayton, G. T. Prior,
T. Thurland, H. Thurland, C. P. A. Morrison (Secretary of the
Association) ; H. Mathews, and J. H. Jessop, of Oxford ; Mr. C.
Bradley, of Reading ; Mr. Heyhoe, of Woodstock, and Mr.
Dolbear, of Oxford. — The Chairman expressed the pleasure of the
members of the Oxford and the District Chemists’ Association
at seeing those who were present ; it was a very awkward and in¬
convenient time for people in the town to have a meeting, as well as
for those who were absent, or else no doubt there would have been a
larger attendance. That meeting, which was an inaugural meet¬
ing, would, they hoped, lay the foundation of a very useful Society,
which would not only bring the members of their trade
closer together in the bonds of friendship, but also be in other ways
beneficial. They had meetings to celebrate great events, or to
mark an era of great prosperity, and he only hoped, small as
that foundation was, they might do something to make their Asso¬
ciation prosperous and themselves individually prosperous, and he
thought they would do that in some measure if they could show
that as chemists they were carrying out in the highest way
possible the responsibilities of their profession. They could not
expect to get higher prices than other people unless they
could do things better than they, and he thought they would do
well to supply good articles and secure the better education pro¬
fessionally of their members. They must not forget that this
education must be the true corner stone of their building. They were
glad to welcome there the highest representative of the pharma¬
ceutical profession, who sympathised with them in all their
difficulties and knew what they wanted. He thought the best
course would be to ask the older members to express their views
about the present situation of things, and probably by discussing
certain points which were burning points they might be able to
arrive at some conclusion which would strengthen the hands of
the Society, and would ventilate some of the grievances which
they felt and perhaps lead to a solution of them. — Mr. Bradley
said he thought it would have been better if they could have had
one or two points brought forward for discussion, but
as they had not, perhaps he might ask what the opinion of the
Society was with regard to the
Increased Fee for Examination,
which was compelling all members of the trade to pay a
registration fee. He believed that the Society had decided to
increase the registration fee in order to get funds and sinews for
warfare, but he was afraid that instead of bringing the members of
the trade together, they would utterly fail ; whereas, had
they gone to Parliament for a short Bill to have enabled them to
charge a registration fee of either a half-guinea or a guinea per
annum, they would have brought the members of the trade
together, and by doing that he thought they would have got a
body which would have enabled them to take any question to
Parliament with a chance of success. He really thought that
instead of increasing the examination fee they would have done
well to have brought all the members of the trade together by
compelling them to pay a registration fee in the first instance. —
Mr. Lacey said he could not quite follow the last speaker.
He could not see where the registration money was to go to. \Y hat
fund would be formed with the proceeds of such registration ?
— Mr. Mathews said, with regard to the new bye-law increasing
the fee, it seemed to him that if the fee was increased gentlemen
who obtained their qualification would value it much more than
now. He did not know whether the Society expected to get a
large increase of revenue therefrom ; from what he could see he
did not think they would. He knew it was argued by
some outside people that they were seeking to make these young
402
PHARMACEUTICAL JOURNAL.
[May 8, 1897
people pay a largely increased fee so as to enable the Society to conduct
the Journal on it present lines, but he did not think the Society
would gain very much by the change. He thought the increase of
the fee would make men value the qualification more ; at the present
time he did not think many of them did value it, because they
went outside and did all they could against the Society.
—The Chairman thought Mr. Mathews had made a very good
point. It was better that the Pharmaceutical Society should be
a voluntary society, so that those who qualified did it for the
honour of the thing. Unfortunately a number of those who had
obtained the qualification had taken advantage of it by going to an
ironmonger’s or draper’s shop and qualifying the whole of the
establishment as bona-fide chemists. The chief difficulty he felt
was that of the name; they did think the name of “chemist”
was their own property, but it was not, unfortunately. There were
“Cash Chemists”
who had no more to do with a chemist than they had
with flying, and it was due to the fact that they had on
their premises a chemist who was supposed to look after
that particular thing. Chemists should see if they could
not get the Legislature to do something in their favour.
They might have transgressed on the doctor’s privileges of pre¬
scribing, but they did not call themselves doctors, and here they
had people prescribing and taking their title as chemists. — Mr.
Bradley said that was the fault of the Pharmacy Act, and it
wanted amending. — Mr. Jessop said he thought they would find
they were in this position that they must ask the Society or the
Government whether they were not going to protect chemists from
people who were now forming themselves into charity institutions,
hospitals, dispensaries, and, last of all, so-called co-operative
stores. The present condition of things was brought about by
the fact that so many men were now reduced to small pharmacies,
what he should call single-handed business. They ought to ask
medical' men to consider this question very seriously, because
they were partly responsible for the origin of the Society ; they asked
for better qualified men of higher standard, but what did they do
now ? Did they support them ? He was afraid they went a long
way from supporting them. People were told now to go to the
drug store, as they could get what they wanted better and cheaper
there. He thought a good deal of the difficulty arose from what
he considered the inaction of the Society. — Mr. T. Thurland said
as regarded the medical men insisting on a better class of dis¬
pensers, it emanated from the Pharmaceutical Society waiting on
medical men and asking them to support the Society in educating
a better class of men. — Mr. Dolbear asked what was the Society
going to offer chemists, suppose they took the trouble to belong to
it ? He was very keen on the acceptance of associates in business
becoming members of the Society and being allowed the privileges
of members. — The Chairman thought the Pharmaceutical Society
had been hampered because so comparatively few of the trade
belonged to it. — Mr. Bradley said he had been a local secretary,
and had found that members dropped off as fast as he could
get them, and they would never get members unless they
could offer them the hope of better things in the future. —
Mr. Clayton said he thought they had mainly two objects before
them. One was to consider if they could see their way clearly to
Join the Pharmaceutical Society,
and if by so doing they could influence them in the direc¬
tion they wished. The other point was the enforcement of
the Pharmacy Act more forcibly to secure their position, and
to protect them from the number of “stores” which were
being formed almost daily. — Mr. Morrison said it was a very
difficult thing to get the majority of chemists to take any interest
in the doings of the Society, and until they could get them to do that
they would not get them to subscribe their guinea. He thought
by reducing the subscription they would get a greater number of
associates, and more interest would be felt in the doings of the
Society. As to the annual registration fee, he was afraid that was a
thing of the very distant future.- — Mr. Lacey said if the registration
fee could be enforced, he would give the Society power to strike off
any man who had managed a store. He helped to get the Pharmacy
Act of 1868 passed, and a most miserable and deplorable job it was.
— The Chairman said the question of increasing tli£ fees for the
examination was a burning question, and he thought
that Mr. Hills would put the matter before them in a manner
which would convince them that, after all, it did not
mean entirely an increase ; it meant ten guineas to be paid at once
for a qualifying examination, and he did not think the amount was
excessive, and when it was given to protect a man’s title to be a
chemist he did not think there should be any grumbling.
The President of the Pharmaceutical Society
was the next speaker. He thanked the meeting for the kind
reception they had given him. When Mr. Ifruce wrote and asked
him to come to Oxford he felt he could do no less than come down,
and he felt also that he should at least hear something to stimulate
pharmaceutical education. He confessed to some disappointment
that nothing had been said of the two great features of the work
of the Society of the last twelve months, but he felt sure that in a
city and neigbourhood as this the Council would have their
sympathies in its desire to improve the education of those
who were coming into the trade after them. He was very glad to
be there that day, because, as he understood, that was the first
meeting of a proposed local association, and he felt that the more
the members of their calling met together and talked over
common ideas, the more they would be able to realise the
difficulties which the Society had to deal with in carrying
on its great and multifarious duties. He therefore rejoiced to
think they were forming an association, because whatever
views might have been expressed hostile to the Society, he believed
he should find some representatives of the chemist’s calling in
this great and important city who would feel loyalty to the
Society. The Pharmaceutical Society was the only body which
existed that could really do much for their common success, and
it was worthy of support. It was one of the most democratic
bodies they could have, especially in the elections to the governing
body. The majority of those returned, when they got behind the
scenes, found they were doing all it was practicable to do in the
interests of their calling, and that there were certainly difficulties
in the way which could only be removed by united action. He
understood, when he assented to Mr. Bruce’s invitation to come to
that meeting, that he should not be asked to make a formal address.
One question had not been raised thatday, butwhichhad been written
about the last few months, and that was the position of town
members versus country members. He could speak with some
freedom, because he was the only London member who was not up
for election , and i t was possible some of the Londoners mi ght be thrown
out. He had occasion, speaking at a dinner in London, to point
out that fifty years ago there were seventeen members out of the
twenty-one resident in London. A change had. taken place from
year to year, until now they had five London members and
sixteen resident in the country. This was the first opportunity
he had had of speaking in the country, and he asked
them to realise, and he was sure that they did, that
the London members fully sympathised with those resident in the
country. They knew the special difficulties attaching to the
carrying on of business in the country, and they had as much
sympathy with them as with those living in towns. But they
must not think they had no difficulties in town. With regard to
the remarks that had been made, Mr. Bradley was in favour, he
thought, of an annual registration fee by Act of Parliament, and
the question arose in his mind whether the Council could get a
united body of chemists to back it up in asking that they should
pay a registration fee. — Mr. Bradley here said he believed the
members of the Pharmaceutical Society would willingly subscribe ;
he would give £5 now for them to go to Parliament in order to get
something of the nature of
A Compulsory Annual Registration Fee.
— Mr. Hills asked what advantage that would be over what
the Council proposed to do at the present time. It proposed
to ask for power to have a fee of ten guineas, which would,
to all intents and purposes, include a sufficient registration
fee for life ; and it was also thought this would be in the interest
of the candidates. This question of the registration fee
was one which had arisen during the consideration of the
Preliminary examination. He was sorry nothing had been said
about that examination. The Committee, when it came to work
upon it, found it necessary to consider the financial aspect, and
in process of time there would probably be a considerable altera¬
tion in the revenue of the Society. There would possibly be a
considerable reduction, how much he did not know. The whole of
the financial aspect of the question was taken into consideration
by the Committee, and it was realised that a man valued his quali¬
fication to some extent by what he had paid for it. The Council
proposed to ask ten guineas for a qualifying examination to enable
a man to carry on business, and if that amount could be secured
May 8, 1897J
PHARMACEUTICAL JOURNAL.
403
there would be sufficient for the registration fee. He thought it
would be a very bad thing not only for the members and the trade
if the Pharmaceutical Society were poor and not able to carry on
its work, he thought that members outside would come to that
conclusion, too, and he was of opinion that a fair revenue was
desirable. It was a mysterious thing that a title for which, in
the individual, qualification by examination was required,
might be taken by a number of unqualified men. They
must recollect that by the interpretation of the Pharmacy Act it
was ruled that limited liability companies were altogether out of
the purview of the Act, and they had come to the conclusion that
a title was also outside the purview of the Act, and he might say
that at the present time the Council was not losing sight
of that point, and was asking to be heard before a Committee of
the House of Lords on the subject. The Council was asking to be
heard as to its views with regard to qualification necessary for
an individual who could obtain only it by examination, and ap¬
parently not necessary for a company. The Council was trying to
do what it could in that direction. He was not prepared to say,
all the same, that if they were successful it would help them very
much. After all, the great difficulty was this, the House of Lords
had said that men might obtain a certain qualification by forming
themselves into a company. If the Council could get all the
chemists in the country to go to Parliament and ask for an
alteration of this decision, none would be more rejoiced than
the present President, but he very much doubted if they were
of one mind in the matter, for they must bear in mind that
many of them were connected with these stores and organisa¬
tions. He should be only too glad to see what he believed
was contemplated in the Pharmacy Act, namely, that an
individual who opened a chemist’s business and who classed
himself as a chemist, should be the only person who
, could do so, and that there should be no possibility for
men to drive through the Pharmacy Act as they now did. As
regarded a single-handed business, he could not conceive of any¬
thing more trying than to carry on such a business. It did seem
very hard that there should be so little remuneration for what was
after all a business requiring a considerable amount of knowledge,
and so much care. Mr. Dolbear had asked what was offered to
those who belonged to the Society. He thought everything was
offered. If the Council could double the incomes of all those belong¬
ing to it, he thought it would be a very powerful Society. The
Council did not go out into highways and hedges to try to find
cases of infraction of the law, but it did take notice of every case
that was brought before it, and it had to do so in cases in which
their own people had broken the law. As regarded the Register,
he should like to see it more perfect than it already was. The
subject of malpractice had been discussed occasionally by the
Council, and it was a difficult one. He did not think it would be
racticable to strike off those who belonged to the “ stores.” In
is opinion it was not quite the right thing for people to stand
outside the Society and criticise it. The only way they could do
anything was by united effort, and if nine out of every ten on the
Register were in the Society, much might be effected. He was
quite willing that associates in business should be members of the
Society, not as a matter of justice, but as a matter of expediency.
He hoped everyone present would join the Society if they were not
already connected with it.
Forfarshire District Chemists’ Association, Wednes¬
day, April 28. — Mr. Charles Kerr in the chair. — As briefly men¬
tioned in last week’s Journal, one of the features of the opening
meeting of this Association was a discussion on
The Proposed New Bye-Laws of the Pharmaceutical
Society.
The Chairman said he had asked Mr. Hill to draft a resolution,
and the following was what he had prepared
“ That this Association approves of the amended bye-laws of the Pharma¬
ceutical Society, and believes they are for the public benefit and in the
interest of pharmacists."
He was not sure, however, that he could move that resolution. It
was rather too strong for him. He believed they would all agree
as to the first part of the bye-laws, relating to the Preliminary
examination. He, however, was not in favour of the £10 10s. fee
for the Minor. He thought it would be hard on the young men,
and that they were moving with too much rapidity. They seemed
to want to make their calling a pure profession, and he did not
think it would ever be that. They would need to have the two
classes of druggists and dispensing chemists as they had in Ire¬
land. Moreover, he thought that if a lad had to remain at school
till he was seventeen or eighteen years of age he would not be
willing to do such things as dusting the shop, and the getting of appren¬
tices, even already, was becoming a very serious business. — Baillie
Doig said the acceptance of the leaving certificates would satisfy
him very well, as a lad could take those at fourteen or fifteen. It
occurred to him that with the excessive development of secondary
education they were preventing many people from entering the
homelier callings. In the case of females for instance, it was now
becoming very difficult to get them to undertake the humbler
duties. If lads were sixteen or seventeen years of age before
they passed the Preliminary examination, it was questionable if
they would do routine work. — Baillie Kermath said his ex¬
perience as a country chemist was that the better educated
boy he could get the better service he got, and the more useful he
became. He thought they ought to aim at getting a better class
of boys, and many of the shop duties should be done by message
boys. — The bye-laws relating to the Preliminary examina¬
tion were unanimously approved of. — Mr. R. M. Lindsay
moved that the Association disapproved of the increased
Minor fee of £10 10s. Tie said the proposal was unfair,
unjust, and dishonest to the young men, and there was nothing
to j ustify it. In 1895 the receipts from these fees was £8740, and the
expenditure £3428, showing a nett profit of £5312 {sic). From 1889
to 1896 there had been an average annual profit of between £3000 and
£4000.— Mr. J. W. Russell seconded the motion, and said all
chemists and druggists should be admitted to full membership.
It was a scandal that a man who passed no examination and could
not tell the composition of water should put up “ Member of the
Pharmaceutical Society,” while a man who passed the Minor
could only be an associate. — Mr. J. H. Thomson said he thought
the Society was entirely justified in raising funds for the
purposes of the Society from examination fees. The members
of the Society had to perform public duties, and many of
those who were registered contributed nothing to the Society’s
expenses. — Mr. Duncan said no reason had been given for this
increase, and the Society had any amount of money which they
simply squandered. The examiners got £3 3s. a day, and it was
a great deal too much. He thought £5 5s. was ample to meet all
expenses.— Mr. Jack moved that the Association approve of
the bye-laws relating to the Minor fee of £10 10s. The work of
the Society was not selfish but primarily intended for the public
welfare. This proposal was intended to raise the trade to a true
and satisfactory position, and would have that effect. The Asso¬
ciation, he felt sure, had the good of the Society at heart, and
would do nothing to prevent these bye-laws being adopted. He
entirely disapproved of the
Extravagant and Exaggerated Language
that had been used about dishonesty and unfairness. The accounts
of the Society were open to all, and everything was honest and
above board. — Mr. J. H. Thomson seconded the motion. — Mr.
Davidson, Montrose, said this money was required for carrying-
out the duties of the Society. He believed the examinations did
not pay in the way that had been represented, and he entirely
supported Mr. Jack’s motion. — Mr. W. L. Currie, Glasgow, did
not consider the £10 10s. fee exorbitant, considering what the
Society had to do in protecting the interests of chemists and drug¬
gists, and in prosecuting those who infringed thu Acts of
Parliament. Out of 15,000 chemists on the Register only
4000 were members of the Society, which he thought was a dis¬
grace to those who held the Society’s qualification, and who claimed
all the rights and privileges of the Society without paying anything
towards the cost. He entirely agreed with the wish that all
chemists and druggists should be members, but that required, an
Act of Parliament. Until such a law was passed it would be impossible
to weld the whole trade into one body. He would regret very much
if that Association should at its first meetinsr give such a straight
slap in the face to the Pharmaceutical Society, and he would
support Mr. Jack’s amendment. — Mr. John Anderson said he was
at first inclined to disapprove of the proposed fee, but on thinking
the matter over he had come to the conclusion that it Was the right
course to take. — Mr. Baillie Ferrier said he would nob say a
word against the Pharmaceutical Society, for it had done a great
404
PHARMACEUTICAL JOURNAL.
[May 8, 1897.
deal to raise the status of chemists. But there was a feeling
among the younger men, especially, against the increased fee, and
he agreed with them and would vote against it. He thought some¬
thing should be done to protect the trade and keep it in their
hands. It was now taking such a shape that any girl could hand
out the things that were made up by specialists. — The Chairman
then put the amendment of Mr. Jack, approving of the bye-laws,
and fourteen voted in favour. The motion of Mr. Lindsay was
then put, and ten voted in favour. The motion in favour of the
bye-laws was therefore declared carried. — The meeting then closed.
North Staffordshire Chemists’ Association, Thursday,
April 29. — Mr. J. Averill, J.P., President, in the chair. — A
general meeting of this Association was held at the North Stafford
Hotel, Stoke-upon-Trent, to consider the proposed alterations in the
bye-laws of the Pharmaceutical Society. There were present :
Messrs. Edmund Jones (Hon. Secretary), T. C. Cornwell, J. W.
Moore (Vice-President), I. H. Heap (Hanley), F. Adams, Vice-
President (Stoke) ; J. W. Poole, Treasurer (Newcastle) ; C. Wain,
(Shelton) ; Prince, Fisher (Longton) ; Viggars, McKee (Tunstall) ;
J. Charles, Hewitt (Burslem) ; Hankinson (Uttoxeter) ; and J.
Brinson (Liverpool). — The Chairman, in introducing
The Proposed New Bye-laws
for discussion, said he might classify them under two heads : (1)
the substitution of the present Preliminary examination by a
certificate from one of the approved examining bodies, such as the
Oxford or Cambridge “ locals ” or the College of Perceptors, and
(2) the raising of the registration fee from five guineas to ten
guineas. After reading the old bye-laws and the proposed altera¬
tions, the Chairman went on to say that as education had advanced
so much in every class of life it was highly important that the
General Education op the Pharmacist
should be kept up to modern requirements. The qualifying exami¬
nation of late years had become more stringent, and there were in
consequence more failures than was the case some years ago.
It would therefore bekinder to let the young men who were entering
pharmacy know by the nature of the Preliminary that a consider¬
able amount of knowledge would be required before they could
obtain the qualification necessary to commence business. The
present Preliminary was not as stiff as it should be, and he thought
the Committee of the Pharmaceutical Society had acted wisely in
deciding that the examination for general education required by
the Medical Council was one which would be most suitable to the
pharmacist. The result would be that a better class of men would
enter the calling, and that the failures in the qualifyin g examina
tions would be considerably diminished.
The Registration Fee.
With regard to the registration fee he thought £5 5s. was
altogether inadequate, because four-fifths of the candidates, after
being put on the Register for life, never supported further the
Society which did so much for pharmacy. He moved the following
resolution : —
“ That this meeting of the North Staffordshire and District Chemists’ Asso¬
ciation, having read and considered the proposed new bye-laws of the Phar¬
maceutical Society, are in full accord therewith, and beg to tender their
hearty support and co-operation to the Council of the Pharmaceutical Society
in their effort to advance the education, interests, and status of chemists
generally.”
— Mr. I. H. Heap seconded the resolution. He thought the raising of
the Preliminary was advisable from every possible point of view.
- — Mr. Charles, whilst endorsing the action of the Council as
regarded the alteration of the examination, thought a fee of
£10 10s. was a little too much. It might be argued that the fee
would keep out unsuitable men. He did not think so, and he was
of opinion that the Associates who provided the money of the
Society should be allowed a seat on the Council and more
privileges than they enjoyed at the present time. — Mr. Hewitt
was of opinion that boys should not be taken as apprentices
unless they had passed the Preliminary examination, or
were in a fair way of doing so, and he thought
the Preliminary examination should be on a level with the London
matriculation. He agreed with Mr. Charles that the proposed fee
was too high. He thought £7 7s. would be quite sufficient. — Mr.
Weston Poole spoke at some length on the matter. He agreed
with the proposed elevation of the Preliminary, but did not think
it went far enough. He did not think the status of any man would
be raised by higher payments. Those who were members of the
Pharmaceutical Society enjoyed a number of luxuries, and they
asked the successful candidates who might not intend to become
members of that Society to pay for them. He did not
think that was fair. If the subscriptions of the members were
not sufficient, then he suggested that the subscriptions should be
doubled. — Mr. T. C. Cornwell said that whether chemists were
members of the Pharmaceutical Society or not they all received
benefit from that Society. He did not think ten guineas at all too
much ; a young man would spend twice as much on a bicycle. — -
Mr. Hankinson said the fact that the successful candidates had to
pay for a number of luxuries which they did not enjoy would not
tend to make them feel friendly towards the Society. There
would be a growing distrust and dislike of the Society’s methods
of raising money. — Mr. Moore said he was glad to see that the
Preliminary examination was to become on “all fours” with that of
the medical profession. He did not think the increased fee would
drive anyone away. There would not be any need, however, for
the increased fee if all members of the trade were subscribers to
the Society. — Mr. Jones thought the examination had been in¬
sufficient and inadequate for the maintenance of that respect to
which the pharmacist was entitled. He thoroughly endorsed the
action of the Pharmaceutical Society in raising their funds by in¬
creasing the fees. — After some further discussion the resolution
was carried nem. con. — Messrs. Poole and Hankinson did not vote.
—-The Secretary announced the receipt of £5 5s. from Messrs.
Evans, Sons, and Co., Liverpool, towards the Library Fund. —
Mr. J. Brinson was asked to convey the thanks of the meeting
to his firm. — Votes of thanks closed the meeting.
Chemists and Druggists’ Society of Ireland (North
Branch), Friday, April 30. — Mr. John Watson in the chair.
This Committee met at 10, Garfield Chambers ; present : Samuel
Clotworthy, Samuel Gibson, John H. Shaw, John Campbell,
Hugh Renton, Joseph Douglass, and W. T. Rankin, Hon. Sec.
The minutes of last meeting were read and confirmed, and a
letter from Mr. W. B. Black, Ballycaster, was read, asking
why grocers and other unregistered persons were allowed to
sell poisons, as many were doing in his district, and stating
that he saw no good subscribing to the Chemists and Druggists’
Society or the Pharmaceutical Society of Ireland, as neither
body instituted proceedings. The Hon. Sec. was instructed to
write that it was the duty of the Pharmaceutical Society of
Ireland to carry out the Act, and that the police had also power
under the Poison Act, 1870, to prosecute. Copies of Rules with list
of officers, etc., were reported as being in the hands of the printers,
and would be circulated in due time. A letter from Mr. R. W.
McKnight, M.P.S.I.,Hon. Sec., Ulster Pharmaceutical Association,
was read, which asked that the Committee of the Society would
arrange to meet with the Committee of his Association in order to
confer with regard to extending an invitation to the British Phar¬
maceutical Conference to meet at Belfast in 1898. The Committee
unanimously agreed to join as asked, the Hon. Sec. to make
arrangements as to time and place. — The Hon. Sec. reported
that Sir James Haslett, M.P., President, was agreed that if the
Conference accepted the invitation if extended to them, they
would receive a very warm and hearty reception. — Some other
routine business having been transacted the Committee adjourned.
Royal Society of Edinburgh, Monday, May 3. — Dr.
W. W. J. Nicol read a paper
“ On Supersaturation.”
The contention is that the phenomena of supersaturation
and superfusion really depend on the capacity of the sub¬
stance to exist in two or more crystalline forms. The
passage of a salt from one crystalline form to another
was beautifully shown by means of lantern slides, and
differently formed crystals of compounds which are not generally
supposed to be alio tropic were likewise exhibited on the screen.
Among these may be mentioned argentic nitrate, acetanilide,
and citric acid. Dr. Nicol has not found one instance,
although he has examined a great variety of compounds,
in which a substance capable of forming a supersaturated
solution does not exist in two crystalline forms, although
there may be difficulty in preparing the less normal form. The
paper is of the nature of a preliminary communication, and a more
complete statement and proof of the theory is reserved for a future
contribution.
Mat 8, 1897]
PHARMACEUTICAL JOURNAL.
405
LEGAL INTELLIGENCE.
PROCEEDINGS UNDER THE APOTHECARIES ACT.
Case against Mr. George Ellinor, of Sheffield.
At the Sheffield County Court on Wednesday, His Honour Judge
Waddy was occupied for a considerable time in hearing a case
•of the alleged usurpation of the privileges of a medical man by a
•chemist. The defendant was George Ellinor, a pharmaceutical
•chemist, who carries on business at No. 127, Spital Hill, Sheffield,
-and the action was brought by the Master,- Wardens, and Society
■of the Art and Mystery of Apothecaries of the City of London, 14,
Austin Friars, E.C., who sought to recover from the defendant a
penalty of £20, for having attended, advised, furnished, and sup¬
plied medicines to and for the use of certain persons without
having obtained a certificate required by the Act of 1815 for better
■regulating the practice of apothecaries throughout England and
Wales. — Mr. G. G. Alexander, barrister (instructed by Mr. F. E.
Eaton), appeared for the plaintiffs, and Mr. Neal defended.
In opening the case, Mr. Alexander said the defendant was a
qualified chemist, and the Apothecaries’ Society alleged that he
had infringed their privileges. The section alleged to be infringed
was Section 20, and the important words were “did act and
practise as an apothecary.” The question was what conduct con¬
stituted acting as an apothecary, and that had already been
decided by Mr. J ustice Cresswell. The real distinction was that
between a chemist and an apothecary, and Justice Cresswell
•defined a chemist as one who sold medicines which were
asked for, and an apothecary as one who himself selected
the medicines and determined on what he ought to give. The
complaint in this case was that defendant — who, it was admitted,
was a duly qualified pharmaceutical chemist, and who also appeared
to hold some qualifications for midwifery, which, however, were
not registered — had been carrying on the business of an apothecary.
He had been visiting patients at their own houses, diagnosing their
diseases, prescribing drugs as remedies, and supplying those drugs.
It was not sufficient to show that this was done on one occasion.
Almost every chemist was occasionally asked over the counter to
^prescribe medicines for simple diseases, such as colds, and the
Society would take no notice of an isolated act like that. But
when it became a habitual practice, as in this case, it was a matter
that they were bound to take notice of. To prove the habitual
practice, he proposed to give evidence with regard to four cases,
which he named.
Mr. Neal objected to the evidence with regard to one of the four
•cases — that of a man named Packard, which Mr. Alexander de¬
scribed as perhaps the most important of all— as that "was not
mentioned in the particulars.
Mr. Alexander, nevertheless, expressed his intention of going
iint i the case.
His Honour said Mr. Alexander was instructed by a great com¬
pany, and was deliberately going to endeavour to hit Mr. Ellinor
with a case of which notice had not been given. He (His Honour)
was very sorry.
Mr. Alexander said that after that expression of opinion, he
would not go into Packard’s case.
His Honour was quite sure it ought not to be done. The Acts
with regard to chemists, dentists, etc., were very beneficial, and
salutary, as they prevented unskilled men from playing with the
health and the lives of others. But it was desirable that in cases,
such as the present, the Society should carry not only the profes¬
sion, but the public with them, and should deal with the matter
in a spirit of dignified justice.
Mr. Alexander said that was exactly the spirit in which they
•approached that case. The action was not brought with any spirit
>of vindictiveness, but as a matter of public duty. He would rely
•on three cases. The patient in one was attended at his own house
by defendant, and received medicine from him for a cold, but it
• could not be clearly shown that the medicine was fetched from
defendant’s shop. In the other two cases, however, the patients,
who were women, sent girls to his shop for medicine. He should
call Dr. Rhodes, Secretary of the Sheffield Branch of the Medical
Defence Union, who would say that all the cases were purely and
simply medical cases. They were not surgical or midwifery cases.
William West Meggitt, butcher, 250, Barnsley Road, said during
ffhe last twelve months defendant had attended him and two
members of his family, and had supplied medicines. Some of them
were made up from Dr. Dyson’s prescriptions, but not all of them.
Mr. Ellinor attended witness for a cold, and prescribed the
medicine.
By Mr. Neal : If he had any little ailment, Mr. Ellinor, who was
his friend, sent him a bottle of physic, but when anything serious
was the matter he sent for Dr. Dyson. He knew perfectly well
that Mr. Ellinor was not a registered practitioner.
Jane Hirst, wife of Alfred Hirst, joiner, 62, Spital Hill, said
she was attended by Mr. Ellinor last July. She had taken medi¬
cines sent by him. They had done her a great deal of good ; she
owed her life to defendant.
Miss Hirst, called to give evidence as to fetching medicine from
Mr. Ellinor, said she had done so, but could not remember whether
it was last year or not.
Mrs. Guest, wife of John Samuel Guest, furnace-man, 7, Salter
Street, said defendant attended her, and said she was suffering
from congestion of the kidneys. She had some medicine from him,
but it did her no good.
Dr. Hugh Rhodes said the cases were all medical ones. He was
cross-examined by Mr. Neal as to who had brought the action. He
did not know, but he did not think the Medical Defence Union, in
the name of the Apothecaries’ Society, had brought the action, and
were supporting it with their funds. He thought that probably
the action was brought by some local medical men.
At this stage the case was adjourned until the following day.
NEW REMEDIES.
\_The notes given under this heading embody recent suggestions in
therapeutics. They cover both new drugs and preparations, and old ones
under new aspects. The word “parts” is used to represent parts by
weight, both for solids and liquids .]
Methylene Blue Internally in Gonorrhcea. — Given internally
in doses of three grains three times a day, Moore has found methylene
blue to be a valuable remedy in treating first attacks of gonorrhoea. It
appears to cut short the acute stage of the disease before any serious
damage is done to the urethral tissues. Whether this is due to the
dye, by its selective action on the gonococci themselves, impairing
their vitality, or whether it be that the tissues in which they grow
are rendered unfavourable for their development is not yet known.
The record of several cases tends to show, however, that methylene
blue exerts a marked and beneficial effect on the disease.—!?. M. J.,
1,97/140.
Malarine. — This is a condensation product of aceto phenone
and paraphenetidine, the formula being — ■
c^<o-c>5<cA
It crystallises in handsome plates of a citron yellow colour, melting
at 88", insoluble in water, slightly dissolved by cold alcohol, readily
so on warming, and freely soluble in chloroform and benzol. It gives
a salt with citric acid, crystallising in rhombohedra, which may be
administered as an antipyretic in doses of 50 centigrammes. It is
stated to be perfectly harmless even in large doses.— Journ. (It
Pliarm. [6], v. , 58, after Ph. Zeit.
Benzo-Naphthol and Bismuth Salicylate in Infantile
Diarrhcea. — A mixture of equal parts of benzo-naphthol and
bismuth salicylate is given in three-grain doses to a child of six
months, this dose being divided in two portions, each given at
intervals of two hours, or into four parts, and one-fourth given every
four hours. Milk diet is stopped for two or three days, and a little
barley water substituted. This regimen is difficult to enforce but
is most important, since it allows the digestive system to throw off
all irritant poisonous matter. This method of treatment is strongly
recommended by Solislchen for the treatment of infantile summer
diarrhoea.- — Rev. de Thirap. , Med. Chirurg., after Med. News,
lxiv., 62.
Scopolamine as a Cerebral Sedative. — Scopolamine has been
found useful as a cerebral sedative in certain mental maladies ; it is
given in doses of a quarter to one milligramme hypodermically.
A quiet sleep of some hours’ duration rapidly follows the dose ;
patients soon become habituated to the drug, hence it is necessary
to gradually increase the dose. — Rev. de Thirap., lxiv., 198.
405
PHARMACEUTICAL JOURNAL.
[MAT 8, 1897
EXTRACTS FROM CONSULAR REPORTS-
“French Oils.”— Mr. E. FitzGerald Law, writing to the
Foreign Office respecting the financial situation in Italy, records a
number of very interesting facts concerning the products and
industries of that country. Referring to the exportation of olive
oil, he says the trade with England is apparently diminishing, and
with Russia it has increased, whilst the French importation, not¬
withstanding tariff difficulties and the fact that whereas Italy
formerly supplied about two-thirds of her olive oil, and now only
supplies about one-third, France still remains by far the most
important buyer, which is probably due to the curious fact that
the best Italian oils are too rich and heavy for public taste in
northern countries, and that the French dealers who understand
preparing the article required, have established a reputation for
so-called French oil, which is in reality frequently prepared from
oils imported from other countries.
Italy’s Chemical Trade with Britain has on the whole declined,
whilst Germany and France have increased their trade. In potash,
English trade holds its own, and in the supply of carbonates and
chlorides there has been no great change. Sulphates, too, are
furnished by England to the extent of about two-thirds of the
total imports, though supplies from Germany and France have
greatly increased, but the importation of oxides from England has
fallen off by nearly 40 per cent. , whilst the quantity imported from
Germany has increased by about 500 per cent. The consumption
of nitrates has also increased by about 70 per cent, to the profit of
direct importation from South America. The total consumption
of chemicals is increasing with requirements for manufacturing
purposes, and to judge from statistical estimates it would appear
that about one-half of these requirements are supplied by Italian
industry.
Sulphur appears to be the most important mineral worked in
Italy, the average annual output during the last three years being
about 400,000 tons, the number of workmen employed in sulphur
mining was estimated, in 1895, to have been 27,000, and the value
of the production given as £953,500.
The Production of Mercury in Italy, although very profitable,
is gradually declining, the output in 1893 being about 19,000 tons, in
1894 about 15,000 tons, and in 1895 about 11,000 tons. The average
annual value of the ore in the last two years was estimated at
about £31,400, and the number of workmen employed in the mines
in 1895 was 501.
Boracic Acid is produced in the provinces of Pisa' and Grosseto
in Tuscany in an average annual quantity of about 2800 tons, and
the value in 1895 was estimated at about £38,500. The number of
borax mines is given as 12, and the number of workmen employed
as 351. Of other minerals worked in Italy the principal are man¬
ganese, antimony, nickel, cobalt, alum, and graphite.
The Ammonia-Soda factory at Lukavica, near Dolnja-Tuzla,
according to the report of Consul-General Freeman, is worked with a
capital of 1,000,000 fl. (£83,333). The annual output of ammoniac
soda being 120,000 met. quintals (11,810 tons), which is exported to
Italy and the Balkan States, where it competes successfully with
the English and Belgian article.
Japanese Opium Trade. — Acting-Consul Layard, reporting on
the opium trade of Tamsui and Kelung for the year 1895, compares
the total value of the imports with that of the previous year. In
1894 the value of imported opium was £168,073, as against
£82,007 in 1895 ; decrease, £86,066, thus showing that the total
import of opium has decreased by more that half. The import of
Benares in 1895 was 37 cwts. , as against 238 cwts. in 1894, and
reached less than a third of its value. The import of Persian opium
has fallen from 1880 cwts. in 1894 to 860 cwts. in 1895. Chinese
opium does not appear in the Customs’ returns, but great quan¬
tities have, without doubt, been landed, by junks, all along the
coast. There has been a large increase in smuggling carried on by
Chinese junks, which has lowered the market to such an extent
that holders of stock have had great difficulty in clearing.
NOVEL PHARMACEUTICAL
APPLIANCES.
NEW SUPPOSITORY MOULD.
G. Lanwer has devised a new form of suppository mould, the
“Ideal,” which possesses some advantages over the usual gun-metal
moulds. By means of one apparatus six different sizes of
suppositories can be produced without in any way soiling the
mould which, in the case of such drugs as iodoform, is a distinct
advantage. From the appended illustration it will be seen that
the mould A (seen in section in B) is hollowed on both sides for
conical suppositories of two different sizes. The stick b tapers
at both ends to fit the hollows on either side of the mould. Each
tapering end of b is ringed with a groove at three points correspond¬
ing again to three different sizes of suppositories to be made. The
tapering end of b is first covered with tinfoil (or waxed paper)
A. r B.
OOOOOO
o ooo oo
OOOOOO
OOOOOO
|Q O O O O Q|
which is pressed flat by the hand, and receives the impressions of
the grooves. The tinfoil covering is then slipped off into the
hollow of the mould. The mass, which may have been melting
during the making of the tinfoil moulds, is now poured in up to>
the desired groove (C). The suppositories are allowed to cool, and
the free tinfoil end folded so as to produce, in a very short space
of time, a, perfect suppository wrapped in foil ready for sale. As
the stick is tapered at both ends, and each end has three grooves,
six sizes of suppository can be made. The apparatus is to be
obtained from G. Lanwer, Ramsloh (Grand Duchy of Oldenburg),
or through a wholesale sundry house. The price of the complete
apparatus is 10 francs.
PLASTER PRESS.
A plaster press for pressing plaster into small sticks is also
manufactured by Franz Hering (Jena). The whole of the press is
kept warm by a circulation of hot water, as indicated in the figure.
May 8, 1897]
PHARMACEUTICAL JOURNAL
407
PARLIAMENTARY NOTES AND NEWS-
Progress. — The Edinburgh University (Transfer of Patronage)
Bill, the object of which we explained in the Journal for April 3,
1897, p. 295, passed the Commons on Monday last. The Plumbers
Registration Bill has also had the good fortune to advance a step.
It has been read a second time, and has been referred to the
Standing Committee on Trade, where its appearance has been
promptly recognised by a page of amendments tabled by Mr.
Tomlinson (Preston). The turn of the early-closing Bills has not
yet arrived, and at present they are in a chronic condition of
deferment. But their time may come, for the business of the
House is in no wise congested, and the opportunities for a private
member this Session are extremely favourable if he can only get
thirty-nine other members to stay in the House with him to
frustrate the “ count out,” which is becoming such a parliamentary
institution.
The Postal Reforms foreshadowed in the Budget statement
may be usefully referred to here as being of commercial interest.
The letter rate of postage in the near future is to be a uniform
charge of 1 d. for any thing under 4 ounces and \d. for every 2 ounces
in excess of that weight, thus abolishing the present distinction
between the rates for samples or books and the rate for letters.
Arrangements are also to be made to effect the delivery of letters
to every addressee in the United Kingdom — a boon to rural dis¬
tricts, quite worth the money it will cost. The reforms will extend
to matters telegraphic, and free delivery of telegrams within three
miles of the receiving office will shortly be in operation. The
charge for delivery above that distance is to be reduced to 3 d.
per mile. It has been the habit of the Post Office Department
to levy a charge for delivering telegraphic messages in London
after a certain hour at night, but the practice will
now be abolished. The parcel rate receives same modification
also. The initial charge of 3 d. for the first lb. remains unaltered,
but afterwards a penny rate per lb. will be charged. Thus, a parcel
under 4 lbs., which is now charged l\d., will, under the new
regime, only cost 6 d. The maximum charge is Is., for which price
a parcel weighing 11 lbs. may be sent. Truly, Mr. Henniker
Heaton must have been profoundly moved by the Chancellor of
the Exchequer’. ^startling epoch-making speech ! The alterations
are presented to the nation as a kind of Jubilee offering and will
take effect from Commemoration Day.
Hope Deferred. — The Food and Drugs Bill introduced by Mr.
Kearley has not yet reached a second reading. It now stands for
Friday, May 28 — a most unfavourable day for private members.
Another Royal Commission is to be appointed. This time
the water supply of London is in question— a matter of some mag¬
nitude and difficulty. The Commissioners have already been
selected. They are : Lord Landaff (lately Henry Matthews), Mr.
J. W. Mellor, M.P. (West Riding, Yorkshire) ; Sir J. Dorington,
M.P. (Tewkesbury) ; Sir G. B. Bruce, C.E. ; Major-General A. de
Courcy Scott, R.E.; Mr. A. de Bock Porter, C.B.; Mr. H. W.
Cripps, Q.C. ; and Mr. Robert Lewis. The President of the
Local Government Board is stated to be willing to bring in a Bill
dealing with the water supply of London, but will not introduce
it until he sees some prospect of making some headway with it.
Physiological Experiments are severely discouraged in the
House of Commons, and it was almost apologetically that the
Home Secretary in reply to Mr. Weir, gave the numbers of those
persons at present possessing licences to perform experiments on
living animals. The numbers were : for England 145, Scotland
52, Wales 1. Of those who held certificates permitting inocula¬
tions and such minor operations without anaesthetics, there were
in England 86, in Scotland 30, and in Wales none at all. For
Ireland the record 'does not come up later than 1895. In that year
there were six licencees, and one held the certificate dispensing with
anaesthetics.
The Half-Holiday Bill, or, to give it the official title, the
Shop Assistants (Half-Holiday) Bill, is still unopposed, but it does
not seem to be able to reach a second reading any more readily
than measures which have been blocked. It has now been deferred
till Thursday, 13th instant.
LETTERS TO THE EDITOR.
“Wanted, an Assistant’s Qualification.”
Sir, — It is quite natural for us— now that such an important step
has been taken by the Pharmaceutical Society towards raising the
status of chemists and druggists — to look around to see what other
improvements can be effected. Mr. John McMillan, in his letter
in your issue of April 17, proposes to institute a new grade in our
ranks. At first sight his proposal seems plausible. On considera¬
tion, however, it is evident that such a proposal would introduce
into our somewhat misunderstood Pharmacy Act only more con¬
fusion. Let us look for a moment at the new assistant whom Mr.
McMillan’s scheme would introduce. He has passed the “Modified
Minor,” and is equally qualified by law to do all that his “ Minor”
superior does — only he may not carry on business on his own
account or manage a branch shop. It is difficult to conceive that
the Legislature would grant powers to a “ Modified Minor” to do
all the responsible work behind the counter that his bigger brother
can do, but prevent him doing it on his own account. If the
Minor examination be unnecessarily advanced for the practical phar¬
macy of to-day, let Mr. McMillan’s new qualification be the only one.
We are all agreed, I think, that the Minor examination is not
too advanced. When school boys of fourteen to sixteen years are
being taught the elements of chemistry and physics, and can dilate
freely about the properties of oxides, sulphides, sulphates, etc.,
the Minor syllabus ought to be the minimum standard for chemists
and druggists, who are supposed to know their business. Instead
of going to Parliament on a fruitless errand, the Pharmaceutical
Society might now do what would have a beneficial result on
assistants, and on the trade generally. There is nothing to hinder
the Society from dividing the Minor examination into two parts ;
the first part of the examination to be in chemistry, botany,
materia medica, and physics, and the second part in dispensing,
prescription reading, and pharmacy law. The fees for each part
should be £5 5s., and the second to follow the first in not less than three
months. Six months at least would thus be required to prepare
for the qualifying examination, and the chances of failure would
be much less than they are at present. An elementary pharma¬
ceutical examination is a desideratum for apprentices, but for this
“ powers” are required.
Edinburgh, April 27, 1S97. W. S. Glass,
Sir, — Evidently Mr. Bessant i3 “down ” on the Major men, and
he is not alone in that respect by any means. I am told that to fill
many positions in retail pharmacies owned by chemists and
druggists a Major man need not apply. Why is it so ? I think it
is simply jealousy, and not, as some say, that he is well up in
theory and not in practice. There are exceptions, of course. I do
not agree with what “ One Who Respects the Major Qual. ” says
about Mr. Bessant’s experience of qualified assistants. We need
no long experience to know it. I have recently met several not
worth their salt in a dispensing business. The principal reason
for such a state of things is that the apprenticeship system is dead,
and that the majority of chemists carry on business on store prin¬
ciples. Draw your own conclusions from the difference between an
assistant of four years’ experience fifteen or twenty years ago and a
modern one. I am afraid there are many apprentices to-day taken
for their premiums and cheap labour. Now comes the question — ■
why should even those who find grave faults with qualified men
advocate a lower standard ? We would then have a most unfair com¬
petition between the qualified and unqualified. What we want is,
a more searching examination in pharmacy and dispensing, and
until the Society can see its way clear to allow a day
each for those two subjects, dissatisfaction will continue.
Every candidate ought to be examined in spreading plasters,
making suppositories, blistering plasters, ointments, mixtures,
emulsions, and pills— varnished, silvered, and white coated. An
employer is deceived when he engages an assistant, guaranteed by
the Board of Examiners to be a dispenser, and finds later that he
is not qualified to do the work in a first-class pharmacy. A large
number of chemists nowadays do not make B.P. preparations, a
tincture is made by adding 1 of So and So’s liquor to 19 of S.V.R.
or S.V. Ten. The same with syrups, ointments, etc., that take
a little time, they are bought. As efficiency in pharmacy and
dispensing is most important, and as many young men, by
not choosing proper situations, do not get an insight into
408
PHARMACEUTICAL JOURNAL.
[May 8, 1897
pharmacy proper, I consider that a whole day for each of those
subjects would no more than suffice to give a candidate fair play.
I fully approve of the increased fee for the Minor, and I propose
that for the extra £5 the examination should last three days
instead of two.
May 1, 1897. A Young Major (93/3).
Chouan Seed and Autour Bark.
Sir, — I have the good fortune to possess a copy of Pomet’s
‘ Histoire generate des Drogues,’ Paris, 1694, and therein I find
reference to the above colouring agents in the following terms : —
“ Le Choiian est une petite graine legere, d’un verd jatinatre,
d’un goust tant soit peu sale, et aigrelet, et de figure assex
semblable an semen contra, excepte qu’il et plus gros et plus
leger. La plante qui le porte est basse et a sa graine par petits
bouquets, 4 peu pres comme le semen contra. II n’a point d’autre
usage en France, que je s§ashe, que pour faire le Carmin, et pour
les Plumaciers, quoy que presentement on s’en serve tres-peu.”
“ L’ Autour est une ecorce fort approchante en figure et en couleur
k la grosse canelle, excepte qu’elle est tant soit peu plus blafarde
au dessus, et de la couleur d’une muscade cassee au dedans, accom-
pagnees de quantite de petits brillants : elle est fort legere et
spongieuse, d’un gout presque incipide et sans odeur. On l’apporte
du Levant, de Turquie a Marseille d’oii nous le faisons venir. Cette
ecorce n’apoint d’autre usage, aussibien que Choiian que pour la
perfection du Carmin. II m’a ete du tout impossible de pouvoir
sijavoir qui etoit l’arbre ou la plante qui porte le 1’ Autour, ce qui a
fait que je n’en ay pu rien dire.”
From which it would appear that our quaint old French author
knew very little about the source of these pigments. And as he
speaks of them as almost out of use in the end of the seventeenth
century, the nineteenth century Genevan writer, quoted by
Pharmacist,” seems somewhat belated in his information. A
“gros” is equivalent to an English drachm, being the eighth part
of the old French ounce of 31 -25 grammes.
Brighton, May 3, 1897. C. S. Ashton.
A Royal College oe Pharmacy.
Sir, — Almost every institution is making an effort to commemo¬
rate the Queen’s Diamond Jubilee, but the Pharmaceutical Society
of Great Britain makes no sign. The Society’s building and its
work are all that could be desired, and pharmacists should be
proud of them, but as a result of evolutionary progress, surely the
day has arrived when its already time-honoured name might
be advantageously changed to that of “ The Royal College of
Pharmacy.”
20, New Street, Dorset Square, May 3, 1897. Thomas Greenish.
ANSWERS TO QUERIES,
Special Hot ice. — Scientific, technical, legal and general information required
by readers of the ‘ Pharmaceutical Journal ’ will be furnished by the Editor as far
as practicable, but he cannot undertake to reply by post. All communications must be
addressed “ Editor , 17, Bloomsbury Square, London, W.C.," and must also be authen¬
ticated by the names and addresses of senders. Questions on different subjects should
be written on separate slips of paper, each oj which must bear the sender’s initials or
pseudonym. Replies will, in all cases, be referred to such initials or pseudonyms,
and the registered number add.ed in each instance should be quoted in any subsequent
communication on the same subject.
Diatomos. — This is a very pure diatomaceous earth ; you can
obtain it from Messrs. Southall Bros, and Barclay, of Birmingham.
[Reply to V. W. B.— 92/11.]
Petroleum Benzene eor Removing Grease Spots. — Yes, light
petroleum benzene is one of the very best solvents for grease spots
on cloth, etc. It is to be preferred to coal-tar benzene for that
purpose. [ Reply to H. H. — 92/39.]
Hydrokinone and Pyrogallol Developer. — A good formula
for this combination would be (a) pyro., 55 grs. ; hydrokinone,
45 grs. ; metabisulphite of potash, \ ounce ; sodium bromide, 20
grs. ; distilled water, to 10 ounces, (b) Washing soda, 2 ounces;'
water, to 10 ounces. For use, mix in equal parts and add an equal
quantity of water. [ Reply to H. C. T. G. — 91/7.
Percentage op Oleo- Resin oe Capsicum in Fruct. Capsici. —
This varies a good deal, some samples being much richer than-
others. A manufacturing firm inform us that the average yield is-
18-5 per cent. [ Reply to Phono. — 92/42.]
Composition of Phonograph Wax. — We believe a mixture of
3 parts of white beeswax and 1 part of carnauba wax is used as-
the basis for phonographic cylinders. [Reply to Phono. — 92/41.]
Glaze for Cookery. — The glaze you mention on joints of meat-
consists of gelatin dissolved in good stock ; about 3 ounces of any
good brand of gelatin to each quart of stock. The meat is simply
dipped in the fluid before it sets. [Reply to H. H. — 92/39.]
Douglas Mixture for Fo'wls. — This appears to- consist of
ferrous sulphate, 8 ozs. ; dilute sulphuric acid, 1 fl. oz. ; water, to-
2 gallons. One teaspoonful of the mixture is added to a pint or'
more of water. We are obliged to the correspondents who have so
promptly furnished the information. [Reply to J. E. D. — 89,32.]
Bronzing Gun Barrels. — The barrels should be thoroughly -
cleansed from all traces of grease by washing them in hot soda-
water. The following mixture is then applied : — Copper sulphate,.
4 parts ; sulphuric acid, 3 ; nitric acid, 4 ; methylated spirit, 5
spirit of nitre, 8 ; tincture of perchloride of iron, 8; water, 160.
The guns are then placed in a damp heat for an hour and a half,,
after which they are again scalded, and the rust is scraped offi
The process is repeated three or four times, after which the barrels*
are cleaned and oiled. A dead black stain may be obtained withi
solution of perchloride of antimony. [Reply to G. S. — 92/37.]
Uranium Intensifier. — There is no uranium intensifier which
will not stain if the negative is not properly washed. For this
method of intensification the negative should be well washed in
water, treated to three successive baths of anthion, which is per¬
sulphate of potassium, for five minutes, and then washed and treated’
with the intensifier, the best formula for which is uranium nitrate, .
100 grs. ; potassium ferrideyanide, 100 grs. ; glacial acetic acid, | oz. p
distilled water, 10 oz. Place the ferrideyanide in a measure and
rinse with water to wash off any ferrocyanide or powder that may¬
be on the crystals, then dissolve. [Reply to Canis. — 92/5.]
Single Solution Developer. — The following would probably
suit you : — Metol, 60 grs. ; hydrokinone, 100 grs. ; potassium
metabisulphite, 240 grs. ; potassium bromide, 48 grs. ; potassium
carbonate, 480 grs. ; distilled water, to 12 ozs. Dissolve the metol.
in 8 ozs. of water, add the hydrokinone, then the metabisulphLto
and bromide, ancl lastly the potash, and make up the bulk. Yota
will probably find this will keep in solution all right. A very
good developer, though somewhat slower acting than the above,,
is : hot water, 12 ozs. ; sodium sulphite, 3 ozs. ; potassium car¬
bonate, 3 ozs. ; glycin, 288 grs. ; potassium bromide, 60 grs.
For use, dilute 1 part with 3 parts water. This is an excellent
developer for negatives, bromides, and lantern slides. It keeps well
and can be used for three or four times or the old developer used
for bromides and slides. [Reply to Anglo-Hibernian. — 88/22.]
INFORMATION WfiNTID,
Saxin.— Information is required by a correspondent (U. D. K.;,
93/2) regarding this substance.
OBITUARY*
Rants. — On April 25, William Rants, Chemist and Druggist,,
London. Aged 58.
Smote — On April 29, John Frederick Smith, Chemist and
Druggist, Liverpool. Aged 70.
Trollope. — On May 2, Edward Hazel Trollope, Chemist and
Druggist, Trowbridge, Wilts. Aged 64.
COMMUNICATIONS, LETTERS, etc., have been received from
Messrs. Arkle, Ashton, Bacon, Barclay, Bayley, Buckfritt, Cocks, Flitcroft,,
Gadd, Glyn- Jones, Goodall, Goodess, Greenish, Hewlett, Hicks, Hill, Hogg.„
Holding Howorth, Junor, Keen, Keif, Kerr, Lewis, Merck, Newsholme, Parkin.
Pickering Rankin, Rees, Robertson Seward Simpson. Walker, Wilkinson.
PHARMACEUTICAL JOURNAL.
409
*
THE TEACHING OF ELEMENTARY BOTANY.
SOME GENERAL IMPRESSIONS.
j^onje "readers of the Journal may possibly be interested
in. tK’e record of a few general impressions which are the result
of experience in examining students in the elements of botany.
After a dialogue at the examination table, the opinions of the
student and the examiner do not always precisely agree as
to the standard which has been reached. The candidate
may be conscious of the possession of a goodly array of
facts, and satisfied that he is in a position to meet the
usual questions with sufficiently technical and concise answers.
On the other hand, the examiner may arrive at the con¬
clusion that behind the veneer of technical terminology
and text-book quotations there is no solid foundation of
intelligent knowledge. It requires but a short experience to con¬
vince an examiner that teacher and student alike frequently
approach the subject of botany from an entirely wrong stand¬
point.
Botanical Knowledge Required by Pharmacists.
A pharmacist does not require a detailed knowledge of botany
for the efficient discharge of his professional duties, nor is it
probable, in most cases, that he will pursue the subject beyond the
examination stage. The schedule of the Pharmaceutical Society’s
examinations very rightly requires as an essential part of the
student’s training that he shall possess a general knowledge of the
elements of botanical science. Such knowledge is not only helpful
to the student as complementary to his acquaintance with other
subjects more directly connected with the practical part of his
profession, but it is of considerable importance as part of that
equipment of scientific culture, which tends to place him on a
higher level than one who possesses nothing more than the facts
absolutely necessary for business purposes.
Although the statement may appear superfluous and the
expression of an obvious and self-evident fact, it is an in¬
telligent grasp of a few botanical truths that is expected in a
competent candidate. The spirit of learning and the methods
of teaching at once assert themselves in the character of
the answers. It needs but a few minutes’ conversation and
the mildest cross-examination to discover, only too commonly,
that interest in the subject and an intelligent common-sense know¬
ledge of principles are alike absent. Quality rather than quantity
is what is required, and if such obvious considerations were not
lost sight of, the subject of botany would lose its apparent diffi¬
culty and assume the form of a refreshing and stimulating draught
rather than that of a distasteful but necessary dose, to be taken in
the smallest possible quantity.
In an examination confined to the more elementary parts of the
science it is surely advisable to keep in view the wider influence
of botanical^knowledge. The man who has learnt ever so little
in the spirit of one who is beginning to observe and to question
Nature, can hardly fail to be led on to a further intercourse with
natural phenomena, and to a sense of having raised himself to a
higher plane of intellectual existence, which makes for something
better than success in an elementary examination.
The Over-Growth of Technical Terms.
It is unfortunate that of late our text-books of botany have
become sadly overloaded with new technical terms which materially
increase the difficulties of a beginner, and too often serve to
obscure the interest and significance of the simplest truths. Every
science must have its nomenclature or technical jargon, and it is
necessary to become familiar with the more important and useful
Vol. LYIII. (Fourth Series, Yol. IV.). No. 1403.
terms. If a little trouble were taken to consider what the tech¬
nical terms mean, and to ask the question why such and such
structures are known by such and such names, the etymology of
the words would often be found a valuable aid to memory, and a
simple method of converting a meaningless expression into a con¬
venient term with a definite significance.
Perhaps one of the most fascinating departments of botany is
that which deals with the physiology or life of plants. By the
aid of a few simple experiments it is perfectly easy to demonstrate
some of the most important rvital attributes of plant life. The
student who glibly tells you that green plants derive their carbon
from the air by assimilation, in answer to the question How plants
obtain carbon, is apt to fancy he has satisfactorily disposed of
the question. If asked what he means by assimilation, and what
part the sun’s rays and chlorophyll play in the process, his mind
appears to be a blank. He has obviously never been in the least
degree interested in solving the problem how the carbon of the
atmosphere is taken possession of by growing plants.
Terms versus Facts.
It happens not infrequently that a student is able to reel off a
string of the most modern terms in describing a transverse section
of a stem, but he knows nothing of the functions of the different
tissues, nor has he the faintest conception of the meaning of the
jargon he has committed to memory. The same candidate calls a
Hyacinth a Lily of the Valley, and regards a Composite flower as a
member of the same family as the Buttercup. He can tell you a
certain fruit has a loculicidal dehiscence, but shows no interest in
the question as to the significance or means of fruit and seed dis¬
tribution. If once the teacher is able to awaken some interest in
the minds of students, the mere knowledge of facts will be readily
acquired. In elementary teaching it is of primary importance to
deal at first with the commonest plants, to demonstrate that
plants live and breathe, and to bring out such points in plant
biology and natural history as cannot fail to be attractive, and
which add a fascinating reality to botanical studies. Unless we
are able to explain the simplest facts of a subject to one
totally ignorant of the technicalities of the science, our know¬
ledge cannot be thoroughly satisfactory. It does not follow
that our knowledge must be such as to enable us to
answer any question which an ignoramus may present to us ;
such questions are frequently the most difficult to deal with.
There is nothing which more surely detects the weak points or
lacunas in our knowledge than an attempt to give a clear exposition
of some of the most elementary facts to a non-botanical inquirer.
If we thoroughly understand and appreciate a certain phenomenon
or set of facts, we should be able to communicate something of
our knowledge to an intelligent layman. Take for example, the
life-history of a fern, which is an extremely interesting story
even to the most unscientific mind, if described with clearness and
a due emphasis of the important points. If, on the other hand,
the most striking facts are obscured by a string of strange terms,
of which the well-crammed examination student has a ne' er¬
failing store, the inquirer would not be disposed to risk any further
questions.
In order that these remarks may not be misunderstood, it
must be added that although it is of the greatest importance
in scientific work to be familiar with the recognised terms, as
without a technical language, concise description and accurate
comparison would be impossible, the point which seems to be
most frequently ignored is that, terms unaccompanied by an
intelligent knowledge of the phenomena or structures for which
they are used are mere tinkling cymbals and counterfeits of the
worst possible type.
410
PHARMACEUTICAL JOURNAL.
[May 15, 1897
PETROLEUM AND ITS PRODUCTS; THEIR PHARMA¬
CEUTICAL USES.
The earlier history of petroleum, and of the solid “ bitumen >
produced by its spontaneous evaporation and oxidation as it oozes
from the strata containing it, refers almost entirely to the medi.
cinal uses to which it was put. The value of petroleum as an
illuminant and heating agent was more or less known, but it appears
to have been entirely overshadowed by its curative powers as an
ointment for wounds and skin diseases, and, to a slight extent, as
medicine for internal use.
Writing at the close of the thirteenth century, Marco Polo (see
The Book of Ser Marco Polo, the Venetian,’ London, 1871, v. i.,
p. 4), stated that the oil of Baku was “ used to anoint camels that
have the mange,” and that “ people came vast distances to fetch it,”
and Jonas Hanway in his ‘ Historical Account of the British Trade
over the Caspian Sea ’ (London, 1754, v. i., p. 263 and 381), stated
that the Russians drank the thinner petroleum as a cordial and
medicine. The solid bitumen found floating on the Red Sea was
early esteemed for medicinal use. Diodorus, a contemporary of
Julius Caesar, stated that it was employed in Egypt for embalming
purposes, and in the ‘ Complete Chymical Dispensatory’ of Dr. John
Schroder (see English translation by Rowland, 1669, p. 281), we
are told tha the “Jewish is best that comes from the Mare
Mortuum.”
Among the liquid varieties of petroleum employed before the
present century, the almost colourless variety obtained in Persia
was most esteemed, and Boerhaave (‘ Shaw’s Translation, 1753, v. i.
p. 117) states that the “oleum terrse” of India was in his time so
scarce as to be “ kept by the Princes of Asia for their own use.”
In Bavaria, the petroleum from the Tegern See was used as early
as 1436 as an ointment under the name “ St. Quirinus’ oil,” while
in Italy, the oil of Modena was similarly employed in the seventeenth
century. In Pennsylvania and New York, petroleum was formerly
used by the Indians as “Seneca oil,” and about the year 1849,
“ American oil,” obtained by roughly distilling petroleum, was sold
by S. M. Kier of Tarentum, on a large scale, for externa application
It is stated that Mr. Kier’s operations were to a great extent the
cause of the earliest attempts at the drilling of Artesian wells for
petroleum.
In England, petroleum under such various names as petroleum,
naphtha, bitumen, oleum terrse, earth-balsam, pisselaeum, pissas-
phaltum, mumia, etc., was used quite as extensively as in other
countries, but the price of the colourless and light coloured oil was
so great that the bulk of that used is stated in James’ ‘ Medica*
Dictionary’ (1745), and in Neumann’s ‘ Chemistry ’ (1759), to have
been fictitious. Among the most approved varieties used were the
light oil obtained from the East, mainly from Persia, the bitumen of
the Dead Sea, and the “ tar ” (or asphalte) of Barbadoes, but an oil
obtained by distilling a sandstone saturated with petroleum, which
occurred at Pitchford in Shropshire, was largely sold as “ Betton’s
British Oil” (Rees’ ‘ Encyclopaedia,’ 1819, article Bitumen).
The purification of petroleum by distillation was carried on by
the early pharmacists, but the product appears to have been usually
regarded as little better than an artificial petroleum, and was only
saleable as untreated crude petroleum.
Crude petroleum varies from an almost colourless, highly mobile
liquid to a green, brown, or almost black oil, as viscous as treacle.
Its composition varies according to the strata from which it is ob¬
tained, but it is mainly composed of hydrocarbons, together with
small quantities of bodies containing oxygen, nitrogen, sulphur,
and in some cases traces of arsenic, phosphorus, etc. The American
oil consists mainly of the saturated hydrocarbons belonging to the
methane or paraffin group, but that of Russia, which is obtained |
from geologically newer strata, is principally composed of member
of the naphthene group which, while isomeric with the olefines and
very similar in properties to the paraffins, belong to the benzene
group, and are therefore entirely different in chemical composition*
It is to this peculiarity that the difference in the properties of the
distillates from the Russian and American oils is attributable.
The various products now obtained from crude petroleum are said
to amount to as many as two hundred, but these are mainly
varieties of the mixtures of hydrocarbons which are known in
commerce as naphtha, benzoline, kerosene, lubricating oils, paraffin,
and vaseline. In order to obtain these in a state of purity, they are
first separated from the crude oil by fractional distillation, followed
by a system of chemical purification by which all colouring matters
and ill-smelling substances are separated.
Petroleum naphtha and the still lighter distillate known as gaso¬
line, are used as solvents as a means for purifying various pharma¬
ceutical and other products, and, like benzoline, for cleaning fabrics*
Considerable quantities of colourless and odourless oil inter*
mediate between kerosene and lubricating oil, are now prepared in
Russia under the names “perfumery oil ” and “ mixing oil.” For
this purpose, the higher-boiling fraction from what is known as
.‘ Solar oil,” is freed from water by blowing a current of air through
t at a temperature of 70° C., until perfectly bright and clear, and
is then treated with ordinary strong sulphuric acid, and finally with
Nordhausen acid with constant agitation. After the evolution of
sulphurous acid, produced by the decomposition of the impurities in
the oil, has ceased, the acid is allowed to seitle and is drawn off, and
the oil is washed with a solution of caustic soda and finally with
warm water.
As described by Rossmassler (‘Die Petroleum und Schmierol-
fabrikation,’ 1893, p. 78), “ perfumery oil ” has a specific gravity of
0-800 to 0 88 5, and does not become yellow or deposit any impurity
after exposure to light. It is employed in the preparation of per¬
fumes, and is known in the German Pharmacopoeia as “ paraffinum
liquidum.”
Mixing oil, which is largely used as an adulterant of other oils, is
usually of a yellow colour, and has a specific gravity of not less
than 0 860, and not more than 0'885.
The principal pharmaceutical uses of petroleum products are,
however, confined to the varieties of paraffin wax, ozokerite, and
vaseline. Paraffin wax is obtained mainly from the higher-boiling
fractions obtained during the distillation of American petroleum
and Scotch shale-oil, and to a less extent, of Indian petroleum.
Russian petroleum yields practically no paraffin, and although large
quantities are obtained in Galicia, the product from that country is
usually known as ozokerite.
For use in the manufacture of pomades, etc., the softer paraffin
wax is preferred, the purer form which is obtained by pressing the
soft wax at low temperatures being too hard for this purposes
although largely employed for the manufacture of the better class
of candles, for the adulteration of beeswax, etc., as a preservative
coating for eggs, and for a large number of other purposes. A
common paraffin wax obtained as a bye-product in the manufacture
of lubricating oils in America, is used in the preparation of
‘‘chewing gum,” while a yellow wax obtained from Galician
ozokerite, and known as “ yellow ozokerine,” is used on the Continent
as soft paraffin wax is used in this country and in America, in the
compounding of ointments and pomades. Like vaseline, paraffin and
ozokerite (which is chemically identical with, and physically but little
different from paraffin wax) are found to possess far greater perma.
nency than lard, and their absolute freedom from any tendency to
become rancid is rapidly leading to their universal use as a medium
for the preparation of ointments.
Mat 15, 1897]
PHARMACEUTICAL JOURNAL.
411
The “ yellow ozokerine,” mentioned above, is largely purified by
means of Nordhausen sulphuric acid, and the colourless product
obtained is employed by French perfumers in the process of
“ enfleurage,” i.e., in the extraction of scents from flowers, etc.
Vaseline is obtained mainly from American oil, but is also pro*
duced from Galician, Russian, and German oils. That from the
three latter countries, though practically the same as from America,
is frequently known as “ ceresine,”or “cerasin.” Although vaseline
was first obtained in America by the Chesebrough Company, it is to
the Germans that we owe the greater part of our knowledge as to
its composition, Engler and Bohm Dingier' s poly technisches Journal,
v. 262, p. 468) having devoted particular attention to the subject.
The method of preparation employed in America is to a great
extent a secret one, but is said to consist in the distillation of
selected crude petroleum in vacuum stills, and the filtration of the
residual pasty mass through animal charcoal. In the Old World,
the treatment is very similar, but considerable quantities of an
“ artificial” vaseline are also prepared by admixture of solid paraffin
with highly viscous paraffin oil. This material is said to be some
times preferred, especially when fluidity at a moderate temperature
is required, and is included in the German Pharmacopoeia, but it is
not perfectly homogeneous, and shows a granular structure and a
tendency to separate into solid paraffin and oil.
V aseline consists of a mixture of solid and liquid hydrocarbons,
the former of which are entirely without crystalline structure, a
feature to which the valuable properties of vaselin are largely due
Like paraffin wax, it consists almost entirely of saturated hydro¬
carbons, the small quantity of oxygen-containing compounds being
almost negligible. Vaseline absorbs a small quantity of oxygen from
the air, but its value for pharmaceutical purposes does not appear
to be reduced thereby. The so-called “solidified petroleum,” which
is employed to a slight extent as fuel and for laundry use, and as a
lubricant, is usually prepared by incorporating liquid petroleum
with soaps, or by saponifying fats in admixture with petroleum. It
is, however, of little commercial importance, and of still less to the
pharmacist.
Dr. Squire has recently described in the Journal of the Society of
Chemical Industry (1889, p. 441) an interesting process in which
petroleum is employed for the purification of crude alcohol. This
process, which not only removes the fusel oil, but also the ill¬
smelling products contained in the common spirit obtained from
molasses, etc., appears to be due to Parsons, of New York, who in
1869 patented the use of paraffin wax for the purpose. The wax
was dissolved in the hot alcohol, which was then diluted to 50 per
cent, strength, whereby the paraffin was precipitated with the fusel
oil, etc. The method now in use is that of Ruffin and Bang, and
consists in replacing the wax by liquid petroleum having a boiling
point of about 140° G.
SUPPOSITORIES AND THEIR MANUFACTURE.
The results of some experiments by Professor Lewin in con¬
junction with Apotheker Eschbaum have appeared in the Deutsche
med. Wochenschri/t. According to Lewin, it is essential that the
medication should be equally distributed in the suppository, and
that it should be readily separable from the basis. The suppository
itself should be as sterile as possible, and so formed as to be easily
inserted, a special point being that the dosage of medicament
should be exact. How far the suppositories at present in use
answer these requirements will be seen from the following short
resumd of the results of the experiments alluded to : —
Cacao Butter Suppositories only allow of an equal distribution
of the prescribed drugs if the mass is mixed with fat or oil and
subsequently rolled out. For this method of preparation Lewin
recommends formulae such as the following : —
Ij!i Kali Iodid . 0,2
Butyri Cacao . . . . 3,0
Adipis Suilli . q.s.
Ut. f. exactissime terendo massa qua forma suppos.
D. tal. dos. No .
It is not advisable to fill the medication into ready-made hollows,
on account of the insufficient distribution in these. The authors
remark that even when the cacao butter has solidified the
regular distribution of the medicine (morphine, cocaine, etc.) in
all suppositories is almost a matter of impossibility in all cases
where the medicine is only added mechanically to the bulk. The
examination of a number of suppositories which had been prepared
in various ways by melting and moulding proved this conclusively,
the greater part of the dose of medicine being usually found in the
tip of the suppository, whether the medicine was added to the
cacao butter dissolved in water or as a powder.
Glycerin-Gelatin Suppositories are, according to the authors,
vastly superior to preparations of cacao butter. The medicament,
which has been dissolved in water, readily mixes with the aqueous
solution of glycerin-gelatin, and is evenly distributed in all
suppositories. Further, the glycerin-gelatin suppository can
be easily introduced into the rectum without loss, where the
moisture of the bowel quickly dissolves it, so that both the
medicine and glycerin are speedily absorbed by the blood. The
disadvantages, however, are that these suppositories are not
always sterile, they are prepared of gelatin, the nature of which
is not always known, and which may contain ingredients injurious
to the human organism. They also contain considerable quantities
of glycerin which may prove irritating to the rectum. The
authors therefore reject this preparation and recommend
Agar Suppositories. — If one part of commercial agar powder
is heated with twenty-nine parts of water for some minutes in
the vapour bath, the result is a mixture which can be easily
poured out and which sets after a little time to a slippery,
tough, and flexible mass which has an acid reaction. This
is neutralised by adding 0,1 gramme of sodium bicarbonate
to 10 grammes of the powdered agar. For the preparation of
agar gelatin they give the following method : — One part of
neutralised agar powder is poured into a small medicine
bottle with the quantity of medicament intended to be used
for a certain number of suppositories ; then 29 parts
of water are weighed and added, and the whole shaken up.
The stopper of the bottle is well tied down, and the bottle placed
into boiling water for five to ten minutes. None of the many
bottles used by the authors cracked in this process. Square pieces
of paraffined paper- (about 4 Cm.) are rolled into pointed paper
bags, the points turned over, and the bags fixed in a suitable
frame on a scale pan. The respective quantities of the hot agar
mass are then weighed carefully into the paper bags, and the
suppositories are preserved for use in the bags. If, for instance,
suppositories of potassium iodide are intended to be manufactured,
1 gramme of neutralised agar powder would be put into a bottle
with 1 gramme of potassium iodide, 29 parts of water added,
and the whole shaken up until the salt is dissolved. The bottle
would then be boiled for five to ten minutes, and the liquid agar
poured into ten paper bags of three grammes each. Some medicines,
as mercurial ointment and bismuth subnitrate, cannot be formed
into suppositories in the manner indicated. These are rubbed in
with the prepared agar mass. Antipyrin e sometimes takes more of
the agar mass. Thus 10 per cent, of antipyrine requires double
and 50 per cent, of antipyrine three times the quantity of the agar
mass stated above.
Tannin Suppositories are prepared without heat. One part of
tannin is mixed with two parts of agar powder and massed with
seven parts of water. The mass is then rolled out and divided.
Nearly all other medicines form perfectly homogeneous mixtures if
worked up into agar-gelatin suppositories. Urethral and other
bougies, and vaginal pessaries, are prepared in an analogous
manner. For the preparation of pessaries a block of wood suitably
hollowed out should be used with a suitable stamp to press wax
paper into the hollows.
Salipyrine in Peliosis Rheum atica. — Treated with salipyrine,
three cases of peliosis have been rapidly cured by Muhlbauer, the
pains disappearing “ like magic,” the ecchymoses vanished, and
the temperature fell very quickly, in one case after a single dose.
— Epit., 1/97/44, after Wien med. Woch.
412
PHARMACEUTICAL JOURNAL.
[May 15 1897
PHARMACEUTICAL SOCIETY
“FIRST” EXAMINATION RESULTS.
A meeting of the Board of Examiners for England and Wales
was held on Wednesday, May 12.
Certificates by approved examining bodies were received from
the undermentioned in lieu of the Society’s examination : — -
Brearley, Samuel Edward ; Bromley.
Cocking, Thomas Tusting ; Sheffield.
Day, John Edwin ; London.
Lawson, George Crisp ; Darlington.
Lishman, Arthur ; Sunderland.
Marriott, Arthur Eustace ; Clapham.
Swinn, Charles Gosling ; Manchester.
Wright, Herbert Henry ; Kennington.
The report of the College of Preceptors on the examination held
on April 13 was received. 469 candidates had presented them¬
selves for examination, of whom 260 had failed.
The following 209 passed, and the Registrar was authorised to
place their names upon the Register of Apprentices and Students : — -
Alexander, John Henry ; Helensburgh
Allan, Edwin ; Aberdeen.
Anderson, David Roger ; Dunblane.
Baker, Alfred Robert ; Leicester.
Bartle, George ; Northallerton.
Baverstock, Willie Eaves ; Lincoln.
Bellamy, Clement James Y. ; Caistor.
Benham, William John ; Braintree,
Blarney, Francis Williams ; Truro.
Bonner, Alexander ; Mintlaw.
Brown, Arnold Fitz-John ; Hawick.
Bruce, John ; Ladybank.
Buchan, Joseph Duncan ; Fraserburgh.
Bull, William John ; Bedford.
Burnett, James ; Methil.
Burns, Wilfrid Harry ; Birmingham.
Burr, Josiah Reginald ; Harpenden.
Burton, Francis J. ; Thomaby-on-Tees.
Butlin, James Franklin ; Liverpool.
Caines, Charles March ; Maida Vale.
Carter, Arthur ; Tamworth.
Chaple, Percy William ; Waltham Cross.
Chrystall, C. G. W. ; Buckhurst Hill.
Clee, Arthur Richard ; Uttoxeter.
Clough, Alfred Hollier ; Ventnor.
Cole, George Harold ; Hough Green.
Connon, William Henry ; Aberdeen.
Coonan, John Woodroffe ; Stockport.
Cooper, Thomas ; Hanley.
Coutts, J ohn ; Glasgow.
Craig, Charles Hawkins ; Edinburgh.
Cran, William Strath ; Peterhead.
Cresswell, Harold S. ; Stoke-on-Trent.
Critchison, James B. ; Scarborough.
Cuthbert, William Steven ; Glasgow.
Darby, Leslie George ; Watford.
Davies, Dan ; Herne Hill.
Davies, David ; Pontypridd.
Davies, J ohn ; Llandovery.
Davison, Henry G. ; Newcastle-on-Tyne.
Dennis, William ; Silloth.
Derry, Alfred ; Wadebridge.
Devine, James ; Glasgow.
Dewar, James R. ; Perth.
Doig, John Allan ; St. Andrews.
Dumo, Duncan Mearns ; Aberdeen.
Edwards, John ; Blaenau Festiniog.
Evans, William Owen ; Ammanford.
Fairbaim, James ; Redcar.
Faulkner, Sidney H. ; King’s Lynn.
Fiddes, Thomas Matthews ; Aberdeen.
Findlay, Robert Miller ; Kilmarnock.
Fisk, William John; Southampton.
Fowle, James Frank ; Long Sutton.
Freason, Dora Julia Mary ; Stevenage.
Fry, Albert ; Taunton.
Furness, Harry ; Clayton-le-Moors.
Gale, Percy ; High Wycombe.
Galloway, Thomas McLaren ; Kirkcaldy.
Golightly, Arthur Grylls ; Hartlepool.
Grant, George ; Leven.
Grant, William Alexander ; Ballater.
Grasby, Richard ; Hull.
Graver, Herbert Hodgson ; Alford.
Green, John Percy ; Stockport.
Greenhill, Joseph John G. ; Maidstone.
Greensmith, Charles C. ; Nottingham.
Griffin, Frederick J. ; Chipping Norton.
Griffiths, Harry John ; Cirencester.
Griffiths, Horace; Newport.
Hardie, Douglas ; Aberdeen.
Hardie, Robert Mills ; Dundee.
Harger, Clement ; Halifax.
Harratt, William Ashby ; Grantham.
Harrod, Charles Edward ; Liverpool.
Heath, Walter Valentine ; Ripley.
Heaton, J ohn ; Burnley.
Hey, Herbert ; York.
Hill, Arthur Charles ; Ellesmere.
Hill, George Grayson ; Rothesay.
Hineh, Albert Robert ; Leicester.
Hind, Ethel Mary ; Rhyl.
Hipperson, Charles W. W. ; Norwich.
Holmes, Albert E. ; Melton Mowbray.
Howson, William Thomas ; Nottingham.
Inman, George ; Manchester.
Jack, Alexander B. ; Dingwall.
Jackson, Charles Henry ; Sunderland.
Janisch, Ellen ; Newcastle-on-Tyne.
Jarvie, George ; Kirkintilloch.
Jeffrey, Alexander Hill ; Govan.
Keats, Frank Hartford ; Plymouth.
Keddie, William Dawson ; St. Andrews.
Kemp, George Mitchell ; Edinburgh.
Kennedy, George ; Seaeombe.
Kirby, Robert Harrison ; Whitby.
Kirkland, Arthur ; Nottingham.
Knight, Frank W. ; Weston-super-Mare.
Laing, John Fraser ; Aberdeen.
Lamont, John ; Glasgow.
Langley, Frederick Gabriel ; Penzance.
Lees, James ; Dumbarton.
Leicester, Charles ; Oldham.
Leslie, William ; Falkirk.
Llewellyn, A. D. ; Ystrad Rhondda.
Lloyd, Edward Gwilym ; Colwyn Bay.
Locke, Robert Grey ; Ipswich.
Love, William Landels ; Kirkcaldy.
McCallum, William ; Edinburgh.
Macdonald, John ; Rothes.
McDonald, John Bayne ; Perth.
McGillivray, Alexander M. ; Peterhead
McIntosh, William ; Glasgow.
McLean, Alexander Bennett ; Glasgow
McNab, Leonard ; Forfar.
Marris, George Wesley ; Grimsby.
Martin, Annie ; Penrith.
May, Frederick Bertram ; Manchester.
Mellor, Ernest Martin ; Uttoxeter.
Michael, George ; Edinburgh.
Miles, Hubert William ; Ramsgate.
Mitchell, J ames ; Broxburn.
Morris, David ; Oswestry.
Mosley, Wilkinson ; Driffield.
Muir, Stephen ; Edinburgh.
Muir, Thomas Herbert ; Haddington.
Murdoch, Joseph C. ; Wishaw.
Neilson, Robert ; Stewarton.
Nicholls, Albert Ambrose ; Hackney.
Nicholson, Leonard Edge ; Bolton.
Norweb, Arthur ; Nottingham.
O’Callaghan, Charles W. ; Warrington.
Onley, Geoffrey Bernard ; Birmingham.
Orr, George Henry Reid ; Gatehouse.
Paddock, Granville Edward ; Liverpool.
Paley, Frederick Gartside ; Blackpool.
Palmer, John Thomas D. ; Liverpool.
Parry, Charles ; Patricroft.
Paterson, Henry Ambrose ; Arbroath.
Patten, Alexander D. FI ; Alnwick.
Patterson, J. W. ; Newcastle-on-Tyne.
Paulsen, John ; N. Shields.
Peasnall, Horace Albert J. ; Norwood.
Perks, Hugh Earl ; Leicester.
Peters, Albert ; Ruabon.
Pettigrew, William ; Lincoln.
Phillips, Philip John ; Carmarthen.
Pirie, James ; Aberdeen.
Pollock, Thomas Lowthiau ; Penrith.
Quinn, Thomas Francis ; Douglas.
Raff an, John ; Huntly.
Ragg, Harry John ; Lower Edmonton.
Richards, Frederick ; Newton Abbot.
Ridehalgh, Lincoln ; Brighton.
Robb, William Ritchie ; Aberdeen.
Robertson, Harry Butchart ; Dundee.
Robertson, Robert ; Eyemouth.
Robertson, William ; Kilsyth.
Robertson, William ; Glasgow.
Young, Jan
Rogers, Robert Isaac ; Rhos.
Ross, Edward ; Wiveliscombe.
Sharpe, John Balderson ; Margate.
Sheldon, Constance F ; Birmingham.
Shelmerdiue, Henry ; Manchester.
Sidebottom, Samuel H. ; Accrington.
Smart, Helen ; Edinburgh.
Smith, Alexander ; Macduff.
Smith, Arthur ; Mansfield.
Smith, Edgar ; Crediton.
Smith, John Beddall, Manchester.
Smith, Thomas ; Farn worth.
Spouncer, Stanley Y. ; Gainsborough.
Stanser, John ; Lincoln.
Stewart, Adam Tennent ; Annan.
Strachan, Robert Guild ; Dundee.
Suiter, John Ross ; Maryport.
Tait, James Nicoll ; Dundee.
Taylor, William Arthur ; Liverpool.
Teesdale, Arthur ; Horncastle.
Thomas, William John ; Llanelly.
Thompson, Thomas John ; Portsmouth.
Tibbies, Edwin ; Birmingham.
Todd, Tom Hart ; Ulverston.
Tucker, Francis Henry ; Burnham.
Tucker, William T. ; Kentish Town.
Tullis, John; Dunfermline.
Turner, George Augustus ; Belfast.
Uttley, John Edward ; Hull.
Vaughan, Thomas William ; Chester.
Veitch, John Alexander ; Manchester.
Ward, William John ; Manchester.
Wardle, Arthur Hampton ; Maidenhead.
Watkins, Charles W. J. ; Abergavenny.
Watson, James H. ; Laurencekirk.
Webb, James Thos. ; Stow-on-the-Wold.
West, Robert Henry ; Halifax.
Westlake, William Smalley ; Sutton.
Whaley, Harold ; Chester.
White, George Harold E. ; Portsmouth.
Wilkinson, Joseph George ; Harrogate.
Will, Norman; Campbeltown.
Williams, Richard Henry ; Lewisham.
Williams, Robert William ; Rhos.
Williams, William N. P. ; Holywell.
Wilsden, Arthur M. A. ; Wooler.
Wilson, Thomas ; Moffat.
Winter, Harry Stanley ; Manningtree.
Yardley, Thomas Edward ; Ruabon.
s ; Glasgow.
The questions set at this examination were published in the Pharmaceutical
Journal for April 17, p. 334.
The following is a list of the centres at which the examination was held, show¬
ing the number of candidates at each centre, and the result : —
Candidates. Candidates.
-A _
"-N
Examined.
Passed.
Failed.
Examined.
Passed.
Failed.
30
16
14
Lancaster .
6
9
4
22
7
15
Leeds .
20
3
17
6
1
5
11
6
5
7
3
4
Liverpool .
27
14
13
5
1
4
42
19
23
6
3
3
Manchester . . v .
39
15
24
Cardiff .
6
2
4
Newcastle-on-Tyne ....
15
6
9
14
5
9
Northampton .
3
1
2
9
4
5
3
1
2
5
2
3
Nottingham .
21
12
9
4
2
2
Oxford .
2
1
1
4
3
2
2
0
18
10
8
Peterborough .
4
1
3
41
21
20
3
4
5
3
2
Sheffield .
3
1
2
42
19
23
7
6
1
Hull . .
12
4
8
9
5
4
4
1
3
York .
5
3
2
Mat 15, 1897.]
PHARMACEUTICAL JOURNAL.
413
DONATIONS TO THE MUSEUM.
At a meeting of the Library, Museum, School and House Com¬
mittee, on Wednesday, May 12, the Curator presented the following
report of donations : —
Dr. O. Hesse, Feuerbach (through Dr. B. H. Paul) Specimen of the Protea
mellifera, from which hydrokinone was first obtained by him as a natural
product.
Messrs. Potter and Clarke, London : — Two living specimens in flower of
Opuntia decumana, Haw., two living bulbs of Urginea scilla, Steinh., and a
specimen of Anthemis cotula.
Mr. C. E. Sage, London : — Specimen of the bark of Viburnum prunifolium.
Messrs. Schimmel and Co., Leipsic : — Leafy twigs of the plant yielding West
Indian Oil of Sandalwood.
PARLIAMENTARY NOTES AND NEWS-
The Public Health Amendment Bill which has just been
introduced into Parliament, and is supported by Sir A. Hickman
(Wolverhampton, W.), Sir A. Rollit (Islington, S.), Sir W. Foster
(Ilkeston), Mr. Staveley Hill (Kingswinford), Mr. Whiteley
(Stockport), Mr. Baldwin (Bewdley), Mr. E. Spencer (West Brom¬
wich), and Mr. J. Heath (N.W. Staffs), is an attempt to carry into
effect the report of the Select Committee which met in 1895 and
1896 to consider Police and Sanitary Regulations Bills. That
Committee drew attention to the enormous waste of time and
money involved in the present procedure whenever a local sanitary
authority desired to make regulations for the preservation of
public health— an application to Parliament being requisite for the
most trivial thing. It is bad enough that matters affecting the
public weal should be subject to the complexities and uncertainties
of private Bill Legislation, but it borders on the absurd that ques¬
tions of, say, the closing of a village cesspool should have to
occupy the attention of the Imperial Parliament. The new Bill
proposes to change all that by giving power to local authorities to
adopt certain clauses of private Bills which have been accepted by
Parliament, and are now in force in various provincial centres.
There is a somewhat grandmotherly ring about some of the
clauses, but as the Bill is mainly a permissive one, it is quite open
for any sturdily independent town to preserve its liberty and a
high death rate. The chief items to which reference may be
made are : — (a) Provisions for enabling medical officers to trace
the source of infected milk, and to prevent the spread of infection
by maintaining supervision over the dairymen and laundrymen of
their districts. Such clauses have already been adopted by St.
Helens, Burton-on-Trent, and South Shields, (b) Imposition of
penalties for sending, or permitting to be sent, meat unfitted for
use as human food, (c) Provisions for the compulsory testing of
suspected drains, the closing of cesspools, and the erection of
suitable sinks.
Recreation is also recognised as an important factor in the
promotion of health, and the Bill provides for the encouragement
and regulation of public sports and amusements. There are
certain Police Clauses, too, relating to the height, structure, and
line of buildings. But the very ■choicest item in the whole pro¬
gramme is that which enables a local board to regulate public
advertisements on walls and hoardings, and confers on the
harrassed citizen the incomparable privilege of sending away—
without stating his reasons — the ubiquitous street organ or German
band.
The Lawyers triumphed on Tuesday last, and the House estab¬
lished a precedent which should be valuable to the medical profes¬
sion and to the pharmaceutical calling. By a majority of 111
to 16 the motion of Mr. Harrison, that the expenses of the
Incorporated Law Society in expelling the black sheep of its flock
should come out of the public purse, was adopted, and the Journals
of the House now bear the record : ‘ ‘ That this House is of opinion
that a portion of the expenses incurred by the Incorporated Law
Society in fulfilling the duties imposed upon it by the Statute
51 and 52 Viet., c. 65, should be defrayed out of public funds.”
What that “portion of expenses” will be has not yet transpired,
but we have sufficient confidence in the legal profession to imagine
that an adequate contribution will be secured.
Parliamentary Art is Long, and the time of the session is
fleeting, hence Major Rasch’s attempt on Tuesday to curtail
Parliamentary speeches and abate a national nuisance. Hence
also Mr. Hazell’s appeal ad misericordiam on behalf of the Mid¬
wives Registration Bill. Why, asks the honourable member for
Leicester, should this Bill, which embodies the unanimous recom¬
mendations of a Select Committee on the subject, be introduced
session after session and dropped for want of time ? and will the
Government either give facilities for considering the measure now,
or, at any rate, hold out some hope that it may be made a Govern¬
ment item next session ? Many persons may be disposed to
sympathise with Major Rasch and Mr. Hazell, and regret that their
attempts to mend the legislative machinery of Great Britain have
failed.
How We Stand. — The Shops Bill is down for the 18th inst.,
The Midwives Registration Bill for the 20th, and the Plumbers
Registration Bill is half-way through the Standing Committee.
Sir Stafford Northcote tables his Registration of Firms Bill from
day to day in the hope of securing a surprise second reading, and
Sir J ohn Lubbock is beginning to despair of piloting the Early
Closing Bill to the haven where he would wish it to be. It is now
deferred till the 18th.
A SIMPLE METHOD OF PREPARING
GLYCEROPHOSPHATES.
The following method by Delage for preparing glycerophosphoric
acid, and from it the various salts which have been much employed
of late on the Continent, is, from its simplicity, well suited for use
in the pharmacy : — One part, by weight, of phosphoric acid, sp.
gr. 1 ‘454, is mixed in a flask with one and a half parts of glycerin,
sp. gr. 1 "242. The flask is fitted with a double-bored cork, fitted
with a thermometer and an exit tube. It is then gradually heated
in the ordinary way over a Bunsen ; at 120“ the liquid assumes a
straw colour, and as the temperature slowly rises it gradually
darkens until 190° is reached, when the colour is that of dark beer,
and vapours of acrolein are given off. The heat is removed, and
the vessel allowed to cool, a viscous mass resulting. 100 grammes
of phosphoric acid and 150 grammes of glycerin should require
about forty minutes to complete the reaction.
To obtain glycerophosphate of lime the resulting liquid
is poured in small quantities at a time into a mixture
of an excess of 50 grammes of lime to 250 grammes of
water. The mixture is stirred, and when effervescence ceases,
allowed to stand for six hours, then filtered. To the faintly yellow
clear filtrate one-half its volume of 90 per cent, alcohol is added,
which throws down a flocculent precipitate of glycerophosphate of
calcium. This is collected, washed with alcohol of the same
strength, re-dissolved in water, and re-precipitated with alcohol
and dried at as low a temperature as possible over a desiccator. In
this manner a white powder is obtained, consisting of masses of
microscopic crystals, soluble in about 20 parts of water, 100
grammes of phosphoric acid yielding about 6 grammes of this
salt. From the mother liquors another salt, having the composi¬
tion of an acid glycerophosphate, is obtained ; this is not precipi¬
tated by alcohol.
The glycerophosphates of sodium and potassium can only be
obtained in solution. Those of magnesium, strontium, and lithium
are really obtained from their carbonates in a similar manner to
the lime salt. The iron salts are easily prepared, ferric glycero¬
phosphate being obtained by the action of glycerophosphoric acid
on moist ferric hydrate, and precipitating the solution with alcohol.
The ferrous salt is prepared in a similar way, using the ferrous
carbonate.
The author gives the following reactions for the pure salts : — In
aqueous solutions they are precipitated by heat ; alcohol and ether
precipitate them ; they give no immediate precipitate with
ammonium phosphomolybdate, nor with magnesium mixture, nor
uranium acetate ; the white silver nitrate precipitate is soluble
in an excess of water ; the white precipitate given by lead acetate
is soluble in acetic acid. When treated with absolute alcohol no
residue should be obtained on evaporating off the solvent. — Bull.
Gen. de Therap. (Section Pharmacol.), i. , 225.
414
PHARMACEUTICAL JOURNAL.
[Mat 15, 1897
LEGAL INTELLIGENCE-
PROCEEDINGS UNDER THE PHARMACY ACTS.
A Case at Airdrie.
At the Sheriff Court House, Airdrie, on Tuesday, May 11, the
case of Bremridge v. John Young, Stirling Street, Airdrie, came
before Sheriff Mair. Accused was charged with selling red pre¬
cipitate in an ointment to Mrs. Jane Lees, and chloroform and
morphine in a mixture to James Lees, on February 13, 1897.
Mr. Robert Watt, solicitor, Airdrie, instructed by P. Morison,
S.S.C., Edinburgh, appeared for the prosecutor, and Mr. Orr,
solicitor, Coatbridge, appeared for the defender.
Mr. Orr took objection to the date not being definitely stated.
The offence was said to have been committed on February 13, or
on one or other of certain other days. He also objected to the
want of specification, as no definite quantity of poison was given
and the quantity might have been infinitesimal. Rhubarb con¬
tained oxalic acid, but it would be absurd to charge a fruiterer for
selling poison when he sold rhubarb stalks. In the third place, he
objected that the accused was not really liable as he was only an
assistant to Mr. Harvie, who was a registered chemist, and that
the latter was superintending the sales.
Mr. Watt, in reply, said the phrase as to the date was
common to all criminal complaints, and it would be
a question on the evidence as to whether the prosecution had
exceeded the usual licence granted to a prosecutor. They might
prove that the sale took place on the date stated. As to the
quantity of poison the Act made no demand as to quantity, and
that also would be settled, as it recently was in Lees’ case, on the
evidence. The liability of accused was settled in the Wheeldon
case.
The Sheriff repelled the first objection, but restricted the proof
to February 13. The second objection was reserved for the merits,
and also the third objection.
Defender then pleaded not guilty, and the diet, if proof, was
fixed for Friday, May 14.
PROCEEDINGS UNDER THE APOTHECARIES ACT.
Verdict against a Sheffield Chemist.
At the Sheffield County Court on Thursday, May 6, before Judge
Waddy, the hearing- was resumed of an action which had been
brought under the Apothecaries Act against George Ellinor,
chemist, of No. 127, Spital Hill, Sheffield. The action was brought
by the Master, Wardens, and Society of the Art and Mystery of
Apothecaries of the City of London, 14, Austin Friars, E.C., who
sought to recover from the defendant a penalty of £20, for having
attended, advised, furnished, and supplied medicines to and for
the use of certain persons, without having obtained a certificate
required by the Act of 1815 for better regulating the practice of
apothecaries throughout England and Wales. — Mr. G. G. Alexander,
barrister (instructed by Mr. F. E. Eaton), appeared for the
plaintiffs, and Mr. Neal defended.
The plaintiffs’ case was completed on the previous day, and was
reported in last week’s issue of the Journal (page 405).
Mr. Neal, on behalf of the defendant, submitted that the
plaintiffs had not made out any case, and he therefore asked the
judge to non-suit them. He said counsel had admitted that an
isolated case of acting as an apothecary was not sufficient to bring
a person within the words of the Statute under which the plaintiffs
sought for a penalty. At the very most his opponents had proved
only one isolated case. He reviewed the evidence at some length
in support of his contention that there had been no actual proof
that the defendant had acted as an apothecary. An apothecary,
he said, was one w-ho prescribed, dispensed, and supplied medicine,
and these three acts must be taken conjointly, not separately. He
went on to argue that the witnesses had not proved that the
defendant had done all three things in their cases.
His Honour (interrupting) remarked that the defendant had
reason to feel proud of the personal appearance of his patients.
The only one who looked at all ill was the lady who threw him over.
Mr. Neal, alluding to a bill which had been produced as sent by
the defendant to a Mr. Meggett, said that the charges were for
attendance, not a word was used about medicine.
His Honour : What sort of attendance ?
Mr. Neal : Professional attendance, as a medical man.
His Honour : That is perfectly frank. I admire your bravery in
admitting it.
Mr. Neal replied that the charge against Mr. Ellinor in this case
was not that he had attended patients ; it was simply a question
of whether he had or had not acted as an apothecary. There was
nothing in the law which prevented the defendant from attending
persons at their houses and advising them as to remedies. In that
sense Mr. Ellinor had attended people.
His Honour : To my mind, there must be something like a man
holding himself up as a person prepared to do these things.
Mr. Neal thought both sides would agree to that view.
Mr. Alexander submitted that that would constitute another
offence. That was holding himself up as a duly qualified medical
man, and he would thereby render himself liable to penalties under
the Medical Acts.
Mr. Neal, continuing his defence, said he felt himself justified in
suggesting that the Judge should construe the evidence with great
literalness, and not draw inferences of any description ; the case
must be proved fully and exactly.
His Honour said he could not stop the case. Mr. Neal had better
proceed.
Mr. Neal pointed out that the defendant had done what he had
done in the most open manner. There had not been the slightest
attempt at concealment. That was not, of course, material to the
issue, but it was material to the defendant’s reputation. He had
by his skill and knowledge won the affection and gratitude of
a number of persons who lived in the district in which his shop
was situated.
His Honour : I think if the result of this action should be to
stop Mr. Ellinor from these practices, there would be far more
lamentation by the people who live there than in the household of
Mr. Ellinor.
Mr. Neal detailed Mr. Ellinor’s many qualifications and diplomas.
He was qualified in midwifery ; he held an M. D. degree of Phila¬
delphia University, was a dental surgeon, and a pharmaceutical
chemist. It was admitted that he was a very clever man, and the
only reason why he had not taken an English medical degree,
which would have entitled him to be registered as a surgeon, was
that he could not spare the time for attending at the hospitals and
to fulfil other requirements which would take him away from his
business. He had not, however, done anything in the way of
surgery.
Defendant being called, said he was a Licentiate of Dublin for
midwifery, a registered dental surgeon, and a pharmaceutical
chemist. His Doctor of Medicine degree of Philadelphia University
had been granted to him as the result of an examination by means
of papers. He had practised medicine for twenty years.
In cross-examination the defendant frankly admitted that he had
both prescribed and supplied medicine to the witness who had been
called. He had a private consulting room for dental purposes, but
had been consulted there and prescribed in medical cases. He had
no doubt the medicine he had prescribed had been delivered from
his shop.
Mr. Alexander, addressing the Court, said after Mr. Ellinor’s
admissions he did not think he had any case to answer. His
clients did not question the respectability of the defendant, who
was not one of those gentlemen who are known as “midnight
chemists.” But the defendant had made a great mistake as to his
legal position. Qualification was one thing, but it was not regis¬
tration, and the defendant did not possess a diploma which was
recognised by the General Medical Council. A man was not per¬
mitted to prescribe and supply medicine who was not a certificated
apothecary, and that the defendant had done.
Questioned by the Judge, the defendant said his practice had
gradually grown until at tbe present time it was a very extensive
one. Among other diseases for which he had advised and pre¬
scribed medicines were measles and small-pox. During the small¬
pox epidemic he had many patients who suffered from that malady.
His Honour, in giving judgment, said if the question before him
was one which affected the moral and social standing of the defen¬
dant, he thought everybody in the Court would agree that it was
of the highest. Unfortunately for the defendant, such matters
did not affect the issue at all. Judge Cresswell had defined an
apothecary as a man who judged internal disease by its
symptoms and applied himself to cure that disease by medicine.
It had not only been proved that the defendant professed this,
but one of his witnesses actually said that he saved her life. He
greatly appreciated the praiseworthy openness of Mr. Ellinor in
the box ; it was straightforward and honest, and did him credit.
May 15, 1897]
PHARMACEUTICAL JOURNAL.
415
At the same time he wished to say as strongly and clearly as
possible, however hard it might seem, that he entirely approved of
that class of legislation under which this case had been brought.
He thought it most beneficial. A man was not allowed to plead
for another in a court of law or to give legal advice who did not
possess the recognised diploma, and it was still more important
that there should not be unqualified men going about the country,
dealing out destructive potions to ignorant or uneducated people.
In this case he had no choice but to find for the plaintiffs ; the
defendant had acted in such an open matter that he (the Judge)
had no difficulty in giving his decision. There would be a verdict
for the amount claimed.
Mr. Neal hoped that in the special circumstances of this case costs
would not be granted.
Mr. Alexander remarked that in previous cases under this Act
costs were granted of the higher scale. He only applied for
ordinary costs and those he must press for.
His Honour said the costs must follow the action in the usual way.
PROCEEDINGS UNDER THE SALE OF GOODS ACT.
Claim against Manufacturers of Arsenical Soap.
An action was heard at Kingston County Court on May 7,
before Judge Lushington, Q.C., in which Mr. Alfred Higgs, J.P.,
chemist and druggist, carrying on business in Richmond Road,
sought to recover from Messrs. Yardley and Co., Ltd., toilet soap
manufacturers, of Tottenham Court Road, £50 as damages for
fraudulently selling him an article purporting to be arsenical soap,
and for retailing which a conviction was recorded against him at
the Borough Police Court.
Mr. Arnold White, barrister, instructed by Messrs. Marsh and
Hope, appeared for the plaintiff, and Mr. A. Spokes, instructed
by Messrs. Ford, Lloyd and Co. , London, was for the defendants.
Mr. Arnold White opened the case at great length, and
recapitulated the events leading up to the conviction of the plain¬
tiff in December last, when he was fined 10s. and ordered to pay
16s. costs for selling as arsenical soap a substance — Dr. King’s
Arsenical Soap — which upon analysis was found to contain no trace
of arsenic whatever. The defendants were personally made aware
of the summons served on his client in respect of their soap, but
they absolutely refused him any assistance, and when he wrote to
them subsequently asking to be reimbursed the expense incurred,
the reply was that they declined to entertain the proposal as their
traveller had stated to his client that the soap contained no
arsenic. Subsequently, they sent him a label for thesoap, bearing the
words, “This soap does not contain an appreciable quantity of
arsenic.”
Mr. Higgs said Messrs. Yardley’s traveller stated, when the order
was given, that the sample offered was genuine arsenical soap of
their own manufacture and equal to any make. On that repre¬
sentation he purchased it. Subsequently, Mr. Challis, the managing
director of the defendant company, admitted to him that there was
no arsenic in the soap. There had been a substantial falling off in
his business receipts since his conviction, the deficiency in January,
February, and March, as compared with the average of the past
ears, being £37 8s. 3d. He had lost more than £50 over this
usiness. His solicitor’s bill was over £20. In cross-examination
by Mr. Spokes he denied that the introduction of Parkes’ Drug
Stores and other stores where less prices were charged had affected
his business ; in fact, the result was quite the other way.
Mr. Joseph Bargery, of Cardiff, but formerly an assistant to the
plaintiff, gave corroborative evidence as to what transpired at the
sale of the soap by the traveller.
Mr. Spokes, in opening for the defence, said a most serious
charge of fraud had been made, but he hoped to show that did
not exist at all. They had all along contended that no arsenic
existed in the soap.
His Honour : Then why, instead of sending a label saying the
soap did not contain an appreciable amount of arsenic, did the
company not advise Mr. Higgs that the soap, as stated by their
traveller, contained no arsenic whatever ?
Mr. Spokes said all soaps contained arsenic, and the term
“ arsenical ” was merely a fancy designation, such as “ Sunlight”
soap, in which no one expected to find sunlight. The whole pro¬
ceedings instituted against the plaintiff were bad, and the
decision of the magistrates was ridiculous. No stretching of the
words within the meaning of the Act could make the soap into a
drug, and the travellers employed by the company were specially
instructed to inform purchasers of the soap that no arsenic was
contained therein.
Mr. Weston Robert Challis, managing director to the company,
after expressing the opinion that “commercial truth” is not the
same as biblical truth, said the words “ Dr. King ” and “ arsenical ”
were merely fancy designations, and he put no arsenic in the soap
because it was his belief that other soaps described as arsenical did
not contain any arsenic. He was not a chemist or a physician, but
it was his belief that a person might plaster his skin with arsenic
without harm. Another reason for not putting arsenic in the soap
was because it was a poison. It was true, however, that he manufac¬
tured carbolic soap, though carbolic acid was a poison. Arsenic was
cheap enough, and they now used it in the manufacture of their
arsenical soap. It was true that the legal expenses of another chemist
who was convicted for selling their soap had been paid by the
company.
Defendants’ travellers deposed that before selling the soap, they
had always stated that it contained no arsenic, and arguments
having been heard on both sides,
His Honour said that if the managing director of the defendants’
company was so loose in his employment of terms, he must not be
surprised if his word suffered whensuch strong evidence was brought
against it. After reviewing the chief features of the case, His
Honour said he thought the institution of the proceedings in the
first case was right and proper, and the defendants’ company there¬
fore became liable in the action now being tried ; he should
consequently award £22 for what had been actually expended.
Dealing with what President Kruger would call moraland intellectual
damage, and having regard to all the circumstances of the case, he
should award a further sum of £10, with costs.
PROCEEDINGS UNDER THE FOOD AND DRUGS ACT.
The Sale of Arsenical Soap.
The case of Houghton v. Taplin came on for argument on appeal
on Friday, May 7, in the Queen’s Bench Division of the High Court,
before Mr. Justice Hawkins and Mr. Justice Wright, sitting as a
Divisional Court. Mr. Alexander Glen appeared for the appellant,
Robert Arthur Houghton, an Inspector of Weights and Measures
to the Surrey County Council, and Mr. Lawless represented the
defendant, a Richmond chemist.
Mr. Glen said this was a special case stated by the magistrates
of Richmond under the Food and Drugs Act, 1875. The purchaser
called at the respondent’s shop, where arsenical soap was advertised
for sale, and as being able to produce complexions like that (holding
up a highly-coloured advertisement poster) on persons who suffered
from pimples, and having some beneficial effect on the skin. The
articular soap which was purchased was found on analysis to
ave no arsenic in it at all, and the magistrates held that it was an
ordinary soap, and that no conviction could be sustained.
Mr. Justice Wright : Do you mean that if a man sold something
as bread which turned out to be bricks there would be no con¬
viction.
Mr. Glen said that was the point. The respondent was sum¬
moned under Section 6 of the Act for unlawfully selling to the
prejudice of the purchaser a drug — to wit, arsenical soap — on
November 24, 1896. Appellant sent his assistant, John Church¬
man, to the shop of the respondent, William Joseph Taplin, and
Churchman paid 6 d. for a tablet of the soap, which he afterwards
handed at the door of the shop to the inspector. Churchman was
sent simply for a tablet of arsenical soap, and he was supplied
with a tablet of Dr. Mackenzie’s arsenical soap, No. 2, wrapped
up in some printed papers which described it as an “innocent”
and perfectly harmless soap, and amongst the papers was the highly-
coloured picture which he had exhibited. On the back of it was a
report purporting to be made by Dr. Griffiths, of Edinburgh,
saying he had tested and examined many samples of the soap.
Mr. Justice Hawkins : What is the good of reading all that? We
are not advertising agents here for Dr. Mackenzie or anybody else.
Mr. Glen, continuing, said he understood his learned friend’s
argument was that the transaction which took place was not the
sale of a drug at all. He, on the contrary, submitted that it was
the sale of a drug, although the thing sold was a sham drug. It
purported to be a soap containing a drug. Dr. Griffiths said it
contained a very small proportion of arsenic, but the quantity
useful for the skin was so small that it was perfectly harmless,
although producing a beneficial effect upon the skin. Among the
advertisements enclosed with the soap was a letter by a lady
written from the Hotel Metropole, in which she said that after using
416
PHARMACEUTICAL JOURNAL.
[May 15, 1897.
the soap the spots on her face had entirely disappeared, though
everything previously tried had failed.
Mr. Justice Hawkins asked who signed that.
Mr. Glen said a lady named Winifred Vernon.
Mr. Justice Hawkins held up the highly-coloured poster and
asked if that was her portrait.
Mr. Glen said there was no evidence to that effect.
Mr. Justice Hawkins then read one of the documents handed in,
which said the soap had the property of rendering the skin white,
and that it was a perfect soap for beautifying the skin and impart¬
ing to it a natural hue.
Mr. Glen said the evidence showed that the purchaser told the
respondent’s assistant that the sample was intended to be sub¬
mitted to analysis, and in answer, the assistant said that did not
matter, as the soap was a proprietary article. Dr. Stevenson, the
county analyst, to whom a third part of the purchased tablet was
submitted, certified that the percentage of ingredients in a soap,
which was free from arsenic, was 100 per cent., and he appended
the observation that there was no authorised formula for making
arsenical soap. Eor the appellants it was contended that arsenical
soap was a drug within the meaning of the Act, and for the re¬
spondents that as the soap contained no arsenic there could be no
conviction, but that if there had been any offence the proceedings
should have been taken under the Merchandise Marks Acts. The
magistrates upheld that contention.
Mr. Lawless said the magistrates held the appellants had had
recourse to the wrong remedy, and that the proceedings, if any,
should have been under the Merchandise Marks Act.
Mr. Justice Wright in giving judgment said he thought the
magistrates were right on this ground only — it appeared that this
was a case of a compounded drug, and the information being
under Section 6 of the Act, they were bound to take notice that by
the terms of Sub-section 3 of that Section the sale of a compounded
drug was excluded from it. If the question had been whether a per¬
son could with impunity sell an article as a drug, but escape simply
because there was no drug in it, he (the Judge) was clearly of
opinion he could not, and that the magistrates would have
power to convict.
Mr. Justice Hawkins thought the whole question seemed to be
whether soap is a drug or not, and he said he agreed that the magis¬
trates were right in their finding. His judgment was entirely ar¬
rived at from the view that this article was not a drug per se, and he
did not dissent in any way from what Mr. Justice Wright had said.
Appeal dismissed with costs.
The Sale of Glycebin and Lime Juice.
At Brentford Police Court, on Saturday last, before Mr. M. Sharpe,
Chairman, and a full Bench of Justices, the third hearing of the
summons issued at the instance of Walter Tyler, the Inspector
under the Food and Drugs Act for West Middlesex, against Mr. J.
W. WTebber, chemist and druggist, of High Road, Chiswick, was
proceeded with. The charge was that defendant had sold glycerin
and lime juice not of the nature, substance, and qqality demanded
(see ante, p. 363).
The prosecution was based on a certificate of Mr. E. Bevan,
official county analyst, that there was no glycerin in the compound,
but the Somerset House chemist appealed to under the Act
certified that glycerin was present to the extent of half a fluid
drachm to eight ounces. This agreed with the evidence given by the
defendant and his witnesses at the first hearing. The summons
stood adjourned in order that all the analysts might be present in
court to prove their certificates.
Mr. Earle now appeared on behalf of the County Council, and
Mr. J. W. Lay again defended.
The former, at the outset, referred to the decision of the
Divisional Court, Queen’s Bench, in Houghton v. Taplin, given the
day previously, and said that he alluded to it as he had reason to
believe the defence would set up the plea that it ruled the present
case. At the proper time he should be prepared to show that it
had no such bearing.
Mr. Lay intimated he should raise such a plea, but the Chair¬
man intimated that the Court would hear the evidence of the
chemists and nothing more.
Mr. E. Bevan was then called. As official analyst he received
a portion of the sample, and he could find no definite traces of
glycerin in it. Being a heavy drug, with a specific gravity of 1 '26
compared with water, it would be the heaviest of the component
parts of the compound. If the bottle, therefore, had been left in
he chemist’s window a long time, the glycerin would sink to the
bottom and the oils would rise, and it would require a great deal
of shaking to get them to re-mix. Supposing the bottle was not
well shaken before being divided, there would be more glycerin
at the bottom than at the top. He could not say which portion
of the bottle came to him. He considered that half a drachm
would be insufficient to have any effect on the compound, which in
his opinion was a drug.
In cross-examination he admitted that it was possible he might
have obtained a portion with less glycerin in it than that sent to
Somerset House, assuming there was insufficient shaking.
Inspector Tyler deposed that the portion sent to Somerset
House would be the portion that remained in the original bottle
after dividing the contents.
Mr. Lay put it to the witness that it would be, therefore, most
likely to contain most glycerin, but Mr. Earle said that he was
prepared to admit that.
Mr. Richard Bannister, of the Government Laboratory at
Somerset House, gave evidence at great length. He said
that he received a sample of the compound and he never
noticed any separation. In fact, it would be difficult for the com¬
ponent parts to separate, providing sufficient art had been used in
mixing them. He and Mr. Lewin together made the tests, and sub¬
mitted 50 grammes of the compound to every possible examination.
They came to the conclusion stated in their Certificate. For
further proof they examined the glycerin separated by burning, by
taking its optical value, and by exposure to the air to note its
physical properties. The quantity they had to work upon was so
small that they were unable to deal with it as they should have
liked. Every test applied indicated glycerin.
Mr. Earle elicited that witness could not say exactly how much
the sample contained in bulk, and then severely examined the
witness as to how he could be sure of his figures if he had no
definite data to base them on.
Mr. Bannister replied that the matter was simple ; as soon as
the percentage was determined it was easy to work it out for eight
ounces.
Mr. Earle : But I want to know where you get your idea about
eight ounces from. Why should you say eight ounces any more
than four or sixteen ? Were you aware that the quantity had been
mentioned in the trade journals, and that the defendant swore at the
first hearing he put in half a drachm of glycerin to eight ounces ?
— I saw it in some of the papers, but whether it was before or after
our certificate was written I cannot say.
Mr. Earle pointed out that the form of the certificate differed
from that given in a similar case at Sunbury. In the latter per¬
centages were used ; here the language was unprofessional. How
was that ?
Mr. Bannister replied that they were instructed to analyse for
glycerin. They desired to be as explicit as possible, in order to
make the certificate intelligible to the Bench. In the Sunbury
case the compound differed.
Mr. Earle : Now, Mr. Bannister, did you put it in that form to
make the glycerin appear larger than it would by percentages 1
— No ; I thought if we put it in percentages the man might not
get justice.
Mr. Earle : It is most unfortunate that gentlemen will try to
decide these cases.
The Chairman : I must say we do not appreciate your distinc¬
tions. We should have been quite able to understand percentages.
By the Court : The compound was not, in his opinion, a drug.
He assumed the bulk he received was equal to the other two por¬
tions. If it were not it was wrongly divided.
By Mr. Lay : He had had thirty-two years’ experience of this
work.
Mr. George Lewin, of Somerset House Laboratory, corrobo¬
rated. He explained also that the certificate was framed in the
way it was to make it simpler for the Bench to understand. He did
not agree that glycerin would sink, but the aqueous parts might. It
would be purely conjectural to say that by standing a long time
the glycerin would go to the bottom of the bottle.
Mr. Michael Conroy, chemist to Messrs. Evans, Lescher and
Webb, stated that he examined the sample left with defendant.
He found it contained glycerin, but he did not go so far as to
ascertain the quantity.
The Bench ruled the summons must fail, but was of opinion
that the portion sent to the official analyst for the county was
from the upper part of the bottle, and that sent to Somerset House
from the bottom, hence the discrepancy in the certificates. They
allowed no costs to either side.
May 15 1897]
PHARMACEUTICAL JOURNAL.
417
NOTES AND FORMULAS.
Sodium Hyposulphite for Parasites in Cattle.
F or internal use sodium hyposulphite can always be got at low
price, thus recommending itself to stock farmers. It can be given
as a drench, 3 ounces to a quart of water, or be dissolved in the
water given to cattle to drink, where it will be inimical to all parasite
worms. Again, it can be pounded up with common salt and
given as a lick, a mode by which large numbers of cattle can be
dealt with. It is recommended as a safe and certain cure for
various parasites, both internal and external, which are frequently
the cause of serious disease in cattle. — Agric. Journ., ix., 672.
The Colour of Alcohols Compared with Water.
Spring (Zeit. Anorgan. Chem. ) has compared the colour of the
first members of the series CnH2n + j(OH) with that of water.
Methyl alcohol is bluish-green, ethyl alcohol a similar colour, but
less intense, amyl alcohol is greenish-yellow. The pure blue colour
of water is gradually more mixed with green as one ascends the
homologous series. A column of water 20 metres long corre¬
sponds in colour with a column of standard solution of copper
chloride (16 ‘32 per cent.) 0’314 metres long. The difference in
colour of the alcohols is due to the presence of the carbon chain.
This is clearly seen by comparing the spectra. The hydroxyl group
absorbs the red rays, and the carbon chain the violet and blue rays
in accordance with the number of the carbon atoms. This is clearly
shown in the case of light petroleum, a mixture of the hydro¬
carbons C6H14 and C8H18, the colour of this is yellow without the
slightest tinge of green, and its spectrum shows only green, orange
and red. — Journ. Chem. Soc. abs., lxx., Org. Chem., 634.
Eucaine Ointment Formula:.
Eucaine Ointment.
Eucaiiwe Hydrochlorici . 1
Ol. Olivse . 2
Lanolin . 7
M. f. unguentum.
This ointment is specially suitable for rendering tissues and painful wounds
anaesthetic.
Eucaine Menthol Ointment.
Eucain* Hydrochloric! . . 10
Mentholi . 2
Lanolin . ad. 100
01. Olivae . 20
M. f. unguentum.
D.S. — To be rubbed in externally. For itching haemorrhoids, pruritus ani, and
pruritus pudendi.
— Therap. Monat., xi. 137.
Gelante : A New Dressing for Skin Diseases.
That prolific originator of skin medications, Professor Unna, has
devised a new dressing composed of gelatin and gum tragacanth,
to which he has given the name “ gelante.” It is prepared as
follows : — Pieces of gum tragacanth are macerated for a month in
twenty times their weight of water ; then they are exposed for a
day to the action of steam, with occasional stirring, and finally
strained through muslin. The same weight of gelatin is
softened in water and submitted to the action of steam
under pressure ; the two masses are next mixed, and the
mixture exposed to the action of steam for two days ; it is
then again pressed through muslin and receives the addition of 5
per cent, of glycerin, a little rose water and 0'02 per cent, of thymol.
The liquid thus prepared contains 2-5 per cent, each of gelatin
and tragacanth. When spread upon the skin it dries rapidly and
forms a pliable varnish. Considerable quantities of medicament
may be added to this basis ; as much as 50 per cent, of ichthyol,
40 per cent, of salicylic acid, resorcin, or of pyrogallol, 5 per
cent, of phenol, and 1 per cent, of mercuric chloride. Bodies
which are incompatible in aqueous solutions, such as salicylic acid
and zinc oxide, ichthyol and various salts are without action on
each other when incorporated with this basis. The property of
drying very rapidly distinguishes gelante from all other water-
soluble dressings, and from the large amount of water it contains
it exercises a marked cooling and refreshing action when applied
to the skin ; it is capable of combining with fatty bodies, and can
be applied cold to the surface. It promises to be a valuable addi¬
tion to dermato-therapeutics, particularly in the treatment of
eczema and psoriasis.— Bullet. Comm., xxiv., 417, after Sem. Med.
Manufacture and Examination of Iodised Cotton.
Soulard recommends the use of cotton wool which has been freed
from fat as most suitable ; 100 Gm. of this is put into a large glass
stoppered bottle in which 8 Gm. of iodine has previously been
placed. The bottle is heated in the water bath for about two
hours, until no more iodine adheres to the sides of the bottle after
cooling. By this process 3 Gm. of iodine is chemically absorbed
by the cellulose. The iodine is more quickly absorbed if the
impregnation is carried out at a temperature of more than 100°, but
the wadding can then be powdered. Soulard determines the free
iodine by pouring 10 C.c. of thiosulphate solution, and
90 C.c. of water on 1 Gm. of iodine wool, stirring the whole well,
filtering 5 C.c. off, and titrating back the excess of thiosulphate
with standard iodine solution. — Pharm. Centralh., xxxviii., 38.
Non-Gritty Soluble Tooth Paste.
Frohmann deprecates all additions to tooth powders and pastes
which rub strongly against the enamel of the teeth, such as
pumice stone or charcoal, also non-soluble products like calcium
carbonate, cuttle fish, and naturally also such articles as salicylic
acid and alum, which affect the enamel. Further he warns against
the use of lactic and tartaric acids. He recommends a tooth paste
of the following composition : —
Thymol . . 0'25
Extracti Ratanhise, solve in . 1-0
Glycerini fervidi adde . . 6’0
Magnesise ustsa . _. . . . . . 0'5
Natrii biboraoiei . . . . 4-0
Saponis medicati, aa . . . . . . 30-0
Olei mentbaj piperitse . . . 1-0
M. To be used after dinner and at night.
— Pharm. Centralh., xxxviii., 50.
Mercuric Chloride as a Remedy for Potato Disease.
For some years past a mercury bichloride solution has been used
at Ciphy as a preventive of the ravages of Peronospora infestans.
A 0 015 per cent, solution of the mercury salt is prepared, the
liquid being coloured by 0 24 per cent, of copper sulphate. In
this mixture the seed potatoes are steeped for about five minutes,
and then thrown into heaps for planting. Immunity from the
disease is the result. The germination of the plants is accelerated
and the seed tubers are better preserved in the ground.
Immersion of the tubers for fifteen days in a solution
of double the above strength did not retard germination.
F or preserving the leaves of the growing plant from infection by
the spores of Peronospora the following mixture will be found
useful : — 100 kilos of quicklime is slaked with about one-third by
weight of water containing 200 grammes of copper sulphate per
litre, the mixture being sprayed in the dry state over the plants
at the rate of 250 kilos per hectare, after the disease has become
fully apparent in neighbouring fields. The powder adheres
strongly to the leaves and will withstand a week’s rain. — Jour. Soc.
Chem. Ind., xv., 917.
418
PHARMACEUTICAL JOURNAL.
[May 15, 1897.
THE STUDEHTS’ PAGE.
THE FLOWERS OF MAY.
The medicinal plants in blossom during this month in
the open air are as follows : — Aconitum napellus, Arcto-
staphylos uva-ursi, Arum maculatum, Asarum europceum,
Berberis vulgaris, Carum carui, Chelidonium magus, - Coch-
learia armoracia, Cytisus scoparius, Cqpiandrum sativum,
Convallaria majcdis, Geranium maculatum, Iris fiorentina, Iris
germanica, Juglans cinerea, Juniperus communis, Laurus nobilis,
Morus nigra, Podophyllum peltatum, Pinus sylvestris and other
species, Prunus laurocerasus, Q,uercus robur, Rhamnus catharticus,
R. frangula, Rheum officinale, R. rhaponticum, and R. tanguticum,
Rosmarinus officinalis, Salix alba, Sanguinaria canadensis, and
Viola pedata. Of these, the inflorescence of the arum, the sensitive
stamens of Berberis, the fruit of Chelidonium, the anthers of Laurus,
the dioecious flowers of Rhamnus catharticus, and the stamens of
Rosmarinus, are especially worthy of examination. Of medicinal
plants requiring protection under glass the following may be seen
in flower in botanip gardens : — Aloe vulgaris, A. plicatilis. Ana-
car dium occidentale, Astragalus gummifer, Cinnamomum cassia, Cis-
sampelos pareira, Cistus creticus, Curcuma longa, Erythroxylon coca.
Quassia amara, and Zingiber officinale. Indigenous wild plants
having especial features of interest are Alchemilla vulgaris, Claytonia
perfoliata (naturalised), Dentaria bulbifera, Geum urbanum, Meny-
anthes trifoliata, Myrrhis odorata, Myosurus minimus, Paris quadri-
folia, Polygonum bistorta, Sanicula europcea, and Viscum album.
SOME NOTES ON CRYPTOGAMS.
One of the most common mosses, Mnium hornum, which grows
in patches of a pale green colour and frequently covers several
square yards of soil in woods or on damp hedge-banks, is now in
a suitable condition for study.
The antheridia are found in a conspicuous terminal rosette at the
apex of the male plants (Fig. A) whilst the archegonia are produced
at the apex of the female plants, but can only be found on
dissection and careful examination. The fruiting capsules are
raised on long stalks and are produced freely (Fig. B).
A longitudinal section taken from the apex of the male plant
and examined under the microscope with the 1-in. objective shows
a number of spindle-shaped bodies (the antheridia, Fig. H).
B
Mnium Hornum. — A, Male plant ; B, Female plant fruiting ; E, Young
fruit showing the oalyptra at the apex and the vaginule at the base ;
F, Archegonium ; G, Paraph ysis from the female plant (magnified) ;
H, Antheridium ; I, Paraphysis from the male plant (magnified) ; L, Leaf
showing the midrib and the thickened margin furnished with a double row
of teeth.
Arranged on a flattened disc and mixed with them are certain
club-like bodies called paraphyses (Fig. I) and a few modified
leaves, called pericluetial leaves, which decrease in size towards
the centre of the head.
A median longitudinal section of the female plant at the apex
will reveal a few flask-like bodies, the archegonia, and mixed with
them some shorter filiform paraphyses (Fig. G), the whole being
surrounded by a number of modified leaves forming the peri-
gynium, and equivalent to the perichsetial leaves in the male
plant. After fertilisation the oospore contained in the arche¬
gonium develops into a sporophyte, which increases in length
upwards and downwards. The part growing downwards
penetrates the apex of the moss stem and forms the
seta or stalk of the fruit, whilst the capsule containing
the spores is developed in the part growing upwards.
In the growth of the sporophyte, owing to the rapid
elongation of the seta or stalk, the body of the archegonium, which
meanwhile has increased considerably in size, is ruptured near the
base, and the upper portion is carried upwards by the growing
sporophyte, forming the calyptra or hood (Fig. E), which, as a
rule, is deciduous ; the lower portion surrounds the base of the
stalk and forms the vaginule or sheath (Fig. E). The capsule is
developed at the top of the sporophyte within the calyptra, and
is covered by a lid, called the operculum, which, in M. hornum
and many other mosses is thrown off finally by the action of an
elastic ring of cells on which it rests, and which forms the annulus.
The removal of the operculum reveals "the mouth of the capsule
fringed with a double row of teeth, forming the peristome. These
teeth being hygroscopic, open when dry, but close up when moist,
thus regulating the escape of the spores from the capsule. Some
mosses have but one row of teeth, whilst others have none. The
number of teeth varies with different species, and in most
instances they form a beautiful object for the microscope.
Note. — As the season is getting advanced and attention may now
be more profitably devoted to flowering plants, it is not proposed
to publish further notes on Cryptogams at present. At the same
time students who experience any difficulties in dealing with
that group of plants are invited to communicate with the Editor,
who will be glad to assist them.
NOTES ON THE PHARMACOPEIA.
Decocta. — To refer to this class of preparations generally,
a decoction, as the name implies, is a preparation made by
a process of boiling, the menstruum being water in all the
official decoctions. Comparing the decoctions with the official in¬
fusions — in which the drug is merely steeped or macerated inwater — it
will be noticed that the former are made from drugs of a dense or
woody texture which do not easily yield their activity to warm water,
but require boiling for adequate extraction (e.g., oak-bark), while
their properties are not damaged by the process. The infusions, on
the other hand, are prepared from drugs of a thinner or looser tex¬
ture, which are readily permeated by the water, and many of them
contain volatile aromatic principles (e.g., orange, buchu), which
would be dissipated during ebullition. In making decoctions,
when the water commences to boil apply the heat so as to keep the
water just simmering. Violent ebullition should be avoided ; it
does not enable the water to extract anything more, since the
temperature of boiling water is not influenced by the rate of ebulli¬
tion, and an undesirable quantity of water is evaporated during
the process. Note that the finished product is to be brought to a
definite volume by pouring water over the strainer, in order to
secure uniformity, since more or less water will be lost by evapora¬
tion, according to the conditions under which the decoction may
have been made.
Emplastra. — These preparations require little notice. The
proportions of mercury, belladonna, opium, and cantharides in the
plasters made from these drugs should be remembered. Lead
plaster enters into the composition of most of them, and soap and
resin plasters are variations of the same constituents, the latter
being the more adhesive on account of the larger proportion of
resin. In spreading plasters it should be remembered that
their properties are damaged by over-heating. Care should there¬
fore be taken to have the plaster-iron only just hot enough to melt
the plaster. If a plaster of more than a few square inches be
required it is best to melt the plaster in a dish, preferably over a
water bath to avoid over-heating.
Ergotinum. — Liquid extract of ergot, being an aqueous extract,
contains mucilaginous and albuminous substances having in this
case no medicinal value. Since ergotin is used chiefly for subcuta¬
neous injection it is desirable to remove these in order to get a
preparation sufficiently concentrated for this purpose. The liquid
extract is therefore evaporated to remove the bulk of the water and
then mixed with a comparatively large quantity of rectified spirit.
This precipitates gum and albumin, and the evaporated filtrate
yields a smaller product than would be obtained by simple evapora¬
tion of the liquid extract.
May 15, 1897]
PHARMACEUTICAL JOURNAL.
419
Pharmaceutical Journal.
Editorial Office : 17, BLOOMSBURY SQUARE, W.C.
Publishing and Advertising Office : 5, SERLE STREET, W.C.
LONDON: SATURDAY, MAY 15, 1897.
THE DUAL FUNCTION OF THE PHARMACEUTICAL
SOCIETY.
Several letters have been received from members of
the Society, suggesting that the statements which have
been put forward in opposition to the proposed in¬
crease of the fee for qualification under the Pharmacy
Act should be replied to in the Journal in order to
prevent the possibility of some persons being misled into
believing them to be correct. It has hitherto been thought
that the statements referred to were so obviously mistaken as
to require no serious refutation beyond that published in the
Journal for March 20, which shows the fallacy of the funda¬
mental allegation as to a loss in the production of the Pharma-
■ceutical Journal being the reason for requiring an addition to
the revenue, and for the proposed raising of the examination
fee. But as something more is desired, advantage may be
taken of the financial statement published last week, which
will serve the purpose desired by our correspondents. Before
•entering upon the discussion of that document, it will be
useful to point out the changes that have taken place in the
position of the Society, and the dual function it has now to
perform towards the public and the entire body of chemists
and druggists, on the one hand, and towards its subscribers
on the other.
Though the work of the Pharmaceutical Society has
always been very largely of a public character it has, since
the passing of the Pharmacy Act 1868, been almost entirely
of that description, and the official recognition it then
received was accompanied by a specific provision in the
Seventh Section of the Act, that such fees as should from
time to time be fixed and determined by any Bye-law
as payable upon every examination and registration, were to
be applicable not only in defraying expenses connected with
the administration of the Act but, “ for the purposes of the
said Society.” That provision may therefore be regarded
as intended to place the Society in a position to
•continue its public work independently of the, income
derived from the voluntary subscriptions of its members
and associates, which had previously been the only
means of promoting the objects set forth in
the Charter, and of carrying out other work of a more
private character, such as the holding of meetings for scien¬
tific discussion, the provision of a library, and the issue of a
journal. All the educational work of the Society being accessory
to the administration of the Act, would be properly chargeable
against the revenue derived from that source. But the dual
function thus established did not extinguish the spirit of
voluntary action which led to the formation of the Society,
and up to the present time the private income derived from
subscriptions has been largely applied to subsidise the
continually increasing public work. This fact is clearly
evident from the financial statement for the year 1896,
.published in last week’s Journal.
It will there be seen that the current expenses of all kinds
amounted to £15,675 Is. 11c?., and classifying the several
items under the two heads of Society expenses and administra¬
tive expenses, the following results are obtained : —
Journal, balance of a/c . £2228 1 9
,, postage . 875 4 6
Society meetings . 48 13 11
Library . 370 1 5
Carriage of books . 19 4 6
Calendar, balance of a/c . 78 17 10
Society expenses . 3620 3 11
These expenses were covered by the private income, con¬
sisting of—
Subscriptions . £4679 17 0
Interest and rent . 337 7 4
5017 4 4
leaving a surplus of £1391 0s. 5 cl., or rather more than the
amount of cash in hand at the end of the year. Hence it is
evident that the predicted impending bankruptcy of the
Society is purely a flight of imagination.
The item of £2228 Is: 9 cl., showing the actual cost of the
Journal to the subscribers, is the balance of expenditure over
receipts, and when divided among the subscribers (5700) it
amounts to rather less than eight shillings a year for each
one, without allowance for the large number of Journals
supplied free to honorary members and others. Even when
the postage (2s. 2d.) is added, the total cost of production
and distribution does not come to more than ten shillings a
year. These data are vouched for by the Society’s auditors,
and they fully support the statements made by Dr. Symes
at Liverpool (see ante, p. 383) in regard to the present cost
of the Journal, just as similar data relating to former years
support the statement of Mr. Park (see ante, p. 362) as to
the average cost of the Journal in the past. The greater
cost at the present time is the result of increased size
and much larger circulation, but it is in no sense to be
regarded as loss, as some of the Society’s critics desire to
represent. Their apparent dread of competition is another
delusion, for the Society’s Journal does not compete with
other publications ; it has a higher position than a mere trade
journal, and competition is altogether on the part of those
from whom it has received the most sincere form of flattery.
If the Journal be one of the “ luxuries ” in which sub¬
scribers to the Society indulge, it is a luxury that has been
provided by their special desire, and they have the satisfac¬
tion of knowing that it is paid for by themselves.
Passing from the finances of the Society as a private
body to those connected with its public work, a different
state of affairs will be seen. The administrative expenditure
last year is shown below : —
Establishment charges : London and
Edinburgh . £5385 6 2
Education . 1501 3 3
Examinations . 3492 9 4
Register, balance of a[c . 9 2 7
Death certificates . 21 10 6
Law costs, balance of ale . 685 3 1
Museum . 536 3 1
Annuities . 425 0 0
Administrative expenses . 12,055 18 0
This amount exceeds the revenue from examinations by
more than two thousand pounds, and this deficiency of
revenue would be only partially reduced by crediting the
amount received as fees from students in the School, because
that is chargeable with payments yet to be made. It is in
420
PHARMACEUTICAL JOURNAL.
[May 15, 1897
public department of the Society’s work that financial diffi¬
culty has been experienced, and since it has become evident
that the public revenue is insufficient for defraying the
increasing expenses incidental to administration of the
Pharmacy Acts, there is undeniable necessity for the pro¬
posed increase of the qualification fee.
In the year 1896 the deficiency was between £2396 14s.
and £1029 12s., and it was met partly by drawing upon the
Society’s private funds and partly by borrowing, for though
£1513 18s. 9 d., borrowed for a similar purpose in the previous
year, was paid off between January and April, a further sum
of £1500 was needed in November to meet the current
expenses of the work carried on. Those expenses bear
comparison with those of other institutions of a similar
character without offering any foundation for the charge
of extravagance which has been made.
The case of last year is by no means exceptional, for since
the passing of the Act in 1868, there has been only one
year (1869) in which the administrative revenue was nearly
equal to the expenses incurred. From that time to the
present there has always been a considerable deficiency in
the amount of public revenue, and the administrative work
has been subsidised by the Society to the extent of some
two or three thousand pounds a year.
From this brief statement of facts, which are borne out by
the financial statements published annually, it will be evident
that the outcry raised during the last two months in some
quarters has been, to say the least, as unreasonable as it was
uncalled for. To inquire into the motive for it would prob¬
ably be more troublesome than profitable, and since we have
reason to believe that most readers of the Journal justly
appreciate the erroneous nature of the representations put
forward to the detriment of the Society, it will suffice to
have called attention to the particulars before-mentioned and
thus to have given any who have been misled an opportunity
of judging for themselves.
METHYLENE BLUE IN MEDICINE.
Pharmacists are well aware how quickly many members
of the medical profession respond to a press notice of a new
remedy, and it is probable that the recommendations of the
internal use of methylene blue, which we have quoted last
week and this (see p. 405 and 426) from the British Medical
Journal , will revive a demand for that substance. But there
are various degrees of purity in methylene blue, the original
and only extensive employment of which has been in the
operations of dyeing. A demand for it for medicinal purposes
having arisen, the pharmacist has to recognise that his
skilled knowledge is called for, those cases requiring that he
shall not be a mere distributor of an article bearing the
required name, but that he shall only supply for remedial
uses that reaching an adequate standard of purity. It is not
an object of these columns to announce special manufac¬
turers of medicines, but it would be well that anyone called
on to supply the remedy should see that it answers to the
description given by Merck, of Darmstadt, viz., “Methylene
Blue, medicinally and chemically pure, free from chloride of
zinc.” As so sent out it is in small granular, dull greenish
crystals, about the size of mustard seeds. The ‘ Extra
Pharmacopoeia’ describes methylene blue as in “ bronze-green
crystals.” The showy massive lumps employed by the dyer
answer to this description, but.there is reason to believe
that their form is no guarantee of chemical purity.
ANNOTATIONS.
The Arsenical Soap Case in which Mr. J. W. Taplin, President
of the Western Chemists’ Association of London, appeared as
defendant some time ago, has been carried to the Queen’s Bench
Division of the High Court of Justice by the local authorities, who
appeared as prosecutors, but the appeal has been dismissed. It
will be remembered that the case was heard originally at Kingston
Petty Sessions (see ante, p. 77), and evidence was there given to
prove that the article which formed the ground of action — Dr.
Mackenzie’s Arsenical Soap — contained no arsenic, or so little
that it could not be detected. The magistrates decided, however,
that since arsenic was absent, the soap could not be a drug within
the meaning of the Sale of F ood and Drugs Act, and the case was
dismissed accordingly. The appeal by the prosecution was heard
on Friday, May 7, and dismissed, as already stated. Mr. Justice
.Wright held that the soap was a compounded drug within the
meaning of Sub-section 3 of Section 6, the very Section of the Act
under which the information was laid. This Sub-section provides
that an offence shall not be deemed to be committed “ where the
food or drug is compounded as in this Act mentioned,” and the
latter words presumably refer to Section 4, which specifies that no
person shall, “ except for the purpose of compounding,” mix,
colour, stain, or powder any drug with any ingredient or material
“ so as to affect injuriously the quality or potency of such drug
with intent that the same may be sold in that state.” Mr. Justice
Hawkins, whilst not dissenting in any way from what Mr. Justice
Wright had said, agreed more directly with the magistrates. He
thought the whole question seemed to be whether soap is a drug,
and he was satisfied that the magistrates were right in finding that,
the particular article in question was not a drug.
“When is a Drug not a Drug?” is the question Mr. Justice
Wright seems to have set himself to answer, and it is curious to
note that his solution of the problem appears somewhat at
variance with the decision in the Armson case, though that, of
course, was under a different Statute. But the fact remains that,
whilst the Court of Appeal has decided that a scheduled poison
when compounded remains a poison within the meaning of the
Pharmacy Act, Mr. Justice Wright holds that the Sale of Food
and Drugs Act excludes the sale of compounded drugs from its scope.
In other words, a drug ceases to be a drug when it is compounded,
and arsenical soap being a compounded drug is beyond the
scope of the Act. It must be confessed, however, that the
worthy judge’s chain of reasoning appears to be no clearer
than the meaning of the word “compounded” in the Sale
of Food and Drugs Act, which is very vague indeed, and it
would probably be unsafe to rely upon his dictum in this matter.
Mr. Justice Hawkins’ judgment is also unsatisfactory, for though
he evidently tends to the opinion that soap is not a drug per se,
he contented himself with upholding the finding of the magistrates
that “ arsenical soap ” devoid of arsenic is not a drug. The result
of the case, therefore, is not likely to prove of any value as
authoritatively settling any of the more important points now in
dispute between chemists and analysts. This is much to be
regretted, and we can only hope that some more suitable case may
shortly come before a divisional court.
Another Arsenical Soap Case before the courts last week is of
interest as throwing some light on the position in which manu¬
facturers and retailers stand to one another. The commercial
aspect of the case (see p. 415) shows that if to sell their goods
manufacturers make false representation by description, retailers
have some remedy under the Sale of Goods Act (56 & 57 Vic.,
May 15, 1897]
PHARMACEUTICAL JOURNAL.
421
1893), Sections 13 and 15, and can sue for expenses incurred
through such misrepresentation, as well as for what President
Kruger and His Honour Judge Lushington describe as moral and
intellectual damage. The evidence of the managing director of
the defendant company affords proof, if such were necessary, how
unsafe it is for retailers to deal in articles containing potent drugs
without satisfying themselves of the actual strength of the same.
He stated in examination that he was not a chemist or a physician,
and that no chemist was employed on the premises, and also ex¬
pressed the “belief” that a person might plaster his skin with
arsenic without harm. Following up this point, apparently,
counsel for defendants made the bold statement that all soaps con¬
tain arsenic, but probably some of the manufacturers of refined
soaps, who so strenuously assert the purity of their goods, will
differ from him on that point. Mr. Higgs is to be congratulated
on the result of this case.
A Glycerin and Lime Juice Case, to which attention has been
previously directed in our pages, came up at Brentford Police
Court for the third time on Saturday last. There had been a
conflict of expert evidence, the Middlesex county analyst having
certified that there was no glycerin present in the compound,
whilst the Somerset House chemists claimed to have detected
glycerin to the extent of half a drachm in eight ounces, the propor¬
tion said to have been added by defendant. The magistrates
therefore adjourried the case in order that the Somerset House
chemists might attend and give evidence in support of their certi¬
ficate. This, as will be seen by our report on page 416, they have
done to the satisfaction of the Bench, and, confirmatory evidence
having been given by Mr. Michael Conroy, the case was dismissed.
But why defendant’s costs were not allowed is not clear, as the
prosecution was a most frivolous one, and no chemist and druggist
should be mulcted because of the inability of a public analyst to
discriminate between hair dressings and drugs properly so-called.
As matters stand, Mr. Webber has been most unjustly treated.
After considerable expenditure of time and money, and in the face
cf great difficulties, he has proved that the prosecution was not
justified, and yet he is punished by having his costs disallowed.
Without mincing matters, it may be stated that the public analyst
had undoubtedly made a mistake, as the absurdity of attempting
to shelter behind the supposed tendency of glycerin to settle to
the bottom in mixtures containing water tends to prove. More¬
over, if he recommended that proceedings should be taken in this
case, besides going beyond his strict duties, he allowed what appears
to be a desire to harass chemists and druggists to induce him to
commit a serious error of judgment. He should feel greatly
indebted to the magistrates, who, out of evident but unjustified
sympathy with him, did their best to “ let him down gently.”
The Government Laboratory has also maintained its position
in the Dalston milk case, referred to a fortnight ago (p. 378). The
public analyst for Hackney had certified that 6 per cent, of water
had been added, and this certificate was practically endorsed by
Mr. Otto Hehner, Dr. Bernard Dyer, and Mr. Bevan. But the
report of an independent analysis of a sample of the same milk at
the Somerset House Laboratory stated that the milk did not show
any conclusive evidence of added water. Mr. Bannister was called
to support this certificate, and the net result of a lengthy examina¬
tion and cross-examination as to specific gravities, proportions of
solids, fats, ash, etc., was to show that the methods of milk
analysis employed by the Society of Public Analysts and at Somerset
House are different. In the end, therefore, Mr. D’Eyncourt said he
believed that all the witnesses had spoken fairly t but where there
was a difference of opinion as to methods of analysis he would not
pretend to decide. The summons was accordingly dismissed, with
seven guineas costs. This, of course, is how such cases should
result, as defendants ought invariably to have the benefit of any
doubt, even to the extent of having their costs allowed.
Compounders op Spirits require to take out a special licence,
and omission to comply with this regulation has caused some little
trouble to a St. John’s Wood wine and spirit dealer, who has done
a considerable business in the manufacture of cordials, such as
ginger brandy, peach bitters, lovage, and sloe gin. Fortunately,
he was able to prove not only that he had acted in ignorance, but
also with the full cognisance of several Inland Revenue officers,
and that during a period of twenty-five years. The irony of the
situation was rendered complete when the summoning officer was
called as a witness for the defence, and acknowledged that he had
told defendant he was acting quite legally. He also expressed the
opinion that defendant would not wilfully defraud the Revenue,
and it is not to be wondered at therefore that Mr. Curtis Bennett,
who heard the case, dismissed the summons and gave the defendant
costs ; for, as he rightly observed, since the Revenue officers knew
well that the cordials had been manufactured for years, the defen¬
dant should have been warned before proceedings were taken. The
magistrate also refused to state a case, when Mr. Alpe made appli¬
cation to that effect, as he said he had dismissed it on the facts.
The moral appears to be that whilst too much care cannot be taken
to avoid getting into difficulties with the Inland Revenue authori¬
ties, it is quite possible to dwell for a time — longer or shorter, as
circumstances may decide — in a fool’s paradise, on the strength of
encouragement given by one or more Government agents in all
good faith.
The Idea op Wine Growing in England is usually associated
with the homely products of rhubarb, currant, cowslip, etc. , but
during the past twenty-one years Lord Bute has been experimenting
at Cardiff with vines, and it is now stated in Public Opinion and other
papers that he has succeeded in making the industry pay. Starting
with three acres of vines, of a description known to thrive well in the
colder parts of France, and planted on a sunny slope in light and
porous loam, the results were so promising that at the end of ten
years eleven acres more were laid out. In 1893 the vines on these
fourteen acres yielded forty hogsheads of wine, which is about
seventy per cent, of what a full crop from the same acreage would
yield in Germany, and this wine fetched in the market three thou¬
sand pounds, whilst some of it, on re-sale, was disposed of for a
hundred and fifteen shillings per dozen. Both bad seasons and
good seasons have been encountered during the twenty-one years,
some being altogether barren, but on the whole the enterprise has
succeeded in a way which is described as astonishing, considering
the fickleness of our climate.
The Poisoning of Elephants is not an art in which chemists
and druggists may expect to excel, the subjects being too rare in
this country. But, if only the facts could be correctly ascertained,
the case reported in Tuesday’s newspapers might serve as a useful
object lesson. An elephant had escaped from the noted premises
of Mr. Cross, at Liverpool, and was not finally captured until it
had got some miles away and done a considerable amount of
damage. Having broken away more than once, and being in a
very uncertain frame of mind, it was thought inadvisable to take
the animal back to Liverpool, and, as the simplest way of killing
it, the use of poison was resorted to. Aconite was first
experimented with, but that only acted as a tonic, producing no
ill effects. Recourse was then had to prussic acid. A large brass
syringe was filled with the poison, and discharged into the
422
PHARMACEUTICAL JOURNAL.
[May 15, 189T
elephant’s mouth, but the animal took prompt steps to avert evil
by taking a large draught of water, with which it washed out its
mouth and then discharged the fluid on to the ground. After an
interval the syringe was again charged, and this time covered
with a cloth by way of disguise. The second dose having been
satisfactorily absorbed another was similarly administered, but it
was not until the lapse of three hours that a fatal result occurred.
What should perhaps, from a chemist’s point of view, be regarded as
the most humorous incident connected with the tragic event was
the mischance of the gentleman who suddenly sent “a thrill of
horror” through the assembled crowd by crying “Father, I am
done.” According to a local report, whilst smoking a cigarette
with his mouth partly open (sic), this individual had inhaled some of
the prussic acid, and he only recovered from its effects after being
pumped upon.
Four Ounces of Morphine is the quantity recently stated to have
been sold to a lady in one week, but it is to be hoped that the state¬
ment cannot be confirmed. The alleged morphinomaniac — a person
of considerable means — was charged at Enfield Petty Sessions
with shop-lifting, and the solicitor for the defence urged that she
was not accountable for her actions, because of the extent to which
she had taken drugs. He said also that a chemist would prove
having sold her four ounces of morphine in a week. If this be
so, we trust the chemist may be able, in the interests of his class,
to show that he was morally justified in acting as he did. The
accused was committed for trial, and more will probably be heard
of the case anon.
The Chemists’ Club (London) held its annual dinner at the
Holborn Restaurant on Thursday, May 6, when the chair was taken
by Mr. Horace Davenport, Chairman of Camwal. He was sup¬
ported by Mr. Walter Hills, President of the Pharmaceutical
Society, Mr. William Martindale, Mr. R. A. Robinson, L.C.C.,
Mr. Richard Bremridge, Dr. Paul, and some fifty or sixty other
representatives of pharmacy and the allied trades. The dinner
was excellent, the toast list brief, and the musical programme
attractive. After the usual loyal toast, Mr. R. A. Robinson
proposed that of “ The Pharmaceutical Society,” which was
responded to by Mr. Hills. Then followed the toasts of “The
Chemists’ Club ’’and “The Chairman,” proposed respectively by
Mr. W. S. Glyn-Jones and Mr. C. W. Martin, and appropriately
responded to by Messrs. Garman and Davenport. Thanks were
subsequently accorded to Messrs. Garman, Dewey, and Goodall
for the satisfactory manner in which they had carried out all the
arrangements in connection with the dinner.
An International Inventions Exhibition is to be held in
London during August and September of this year, at the Marl¬
borough Hall, Polytechnic Institute, Regent Street, W. It is
intended to exhibit inventions and improvements relating to
science, industry, arts and crafts, hygiene, and alimentation, and
with this will be combined an international prize competition and
a special exhibition of dentistry and dental surgery. All applica¬
tions for information should be addressed to the Offices of the
Exhibition, 18, Hart Street, London, W.C.
Theodore Bent, the well-known author of the * Ruined Cities
of Mashonaland’ died at his residence in Great Cumberland
Place, London, on Wednesday, May 5. He had just returned
from a voyage to Socotra and an exploration of South Eastern
Arabia. Although chiefly an archaeologist, Mr. Bent rendered some
service to botanical science in exploring the flora of Southern
Arabia during his two previous journeys to that country ; the
results of which he contributed to Kew. On the present occasion he
had promised to endeavour to obtain for the Museum of the Phar¬
maceutical Society specimens of the plant yielding Yemen myrrh.
Unfortunately, both he and Mrs. Bent contracted malarial fever, and
in his case acute pneumonia supervened during the return voyage
to England, and proved fatal on his arrival home.
Nitrous Oxide and Destructiveness may stand in the rela¬
tion of cause and effect, but the ingenious defence of an individual
who was lately charged at Bow Street with breaking a window
was not likely to gain credence. According to this worthy, the
gas employed for dental purposes at St. Bartholomew’s Hospital
was solely answerable for his breaking both the law and a window,,
but either his susceptibility is unique or the gas under the influence
of which his teeth were extracted must have been of peculiar
potency, though probably the magistrate’s view of the case, as,
indicated by his ordering the delinquent a month’s imprison¬
ment, is the correct one, viz. , that the gas was used as a cloak for
the frailty of defendant’s nature.
In Working with X-Ray Tubes, their efficiency is apt to
become impaired, and experimenters will therefore welcome the?
plan which T. W. Ireland and E. H. Howlett describe in the
British Medical Journal for increasing the efficiency of a tube
by simply wrapping its cathodal extremity in damp cotton¬
wool or lint. One end of the material touches and surrounds-
the bulb at the cathodal end, whilst the other is attached to the
cathodal wire. One bulb, that had refused to light up under¬
normal conditions, became flooded with a beautiful blue-green
effulgence, which is designated the most effective form both
photographically and optically, after attachment of the cotton¬
wool or lint. The power of the tube appears to be increased and
the working of the tube rendered constant by this ingeniously -
simple device, whilst the tube continues to act efficiently as long as-
the current is passing. Moreover, the trouble of heating the bulb is
avoided, and the life of the tube prolonged. No loose fibres of cotton¬
wool or lint must be allowed to hang round the bulb, and if the
anodal connection be also carefully adjusted sparking will not take
place, whilst the trouble caused by constantly increasing electrical,
resistance will be obviated.
A Course of Botanical Lectures is being delivered at the
Apothecaries’ Hall, Blackfriars, E.C., by Professor Oliver, of
University College, and in a letter dated May 7, addressed to the
President of the Pharmaceutical Society, it is intimated that the
Master and Wardens of the Society of Apothecaries will be pleased
to see any members of the Pharmaceutical Society who may wish
to attend the lectures. The course deals with the diseases of plants,,
and the subject of the first lecture, delivered on Tuesday afternoon
last, was “ The Plant in Health and Disease.” The remaining
lectures will be delivered on consecutive Tuesday afternoons at
3.30, and will treat of “Witches’ Brooms,” “Some Diseases of
Cereals,” and “ The Diseases of Timber.”
Anozol or Deodorous Iodoform is the name proposed by Dr.
Policarpo Diaz, of Salamanca City, Mexico, for a mixture of iodo¬
form and thymol. Writing to the Spatula, he recommends that
the thymol be powdered and mixed with crystallised iodoform, in
the proportion of ten to twenty centigrammes to each gramme.
The odour of the resulting mixture is said to be that of the thymol
only, the iodoform being completely masked. The name suggested,,
which somewhat too closely resembles “ anusol,” applied to the-
bismuth salt of iodo-resorcin-sulphuric acid, means free from
objectionable odour. Whether the result of blending the thymol
and iodoform odours will be as satisfactory as claimed is doubtful,
but readers can easily satisfy themselves about the matter.
MAY 15, 1897]
PHARMACEUTICAL JOURNAL.
423
JflEETIfJGS Op SCIENTIFIC SOCIETIES
- 4 -
Chemical Society, Thursday, May 6. — Professor Dewar,
F.R.S., President, in the chair. — Being a ballot night there was a
very good attendance. The President, after the usual preliminary
business, announced that there had been a re-count in the matter
of the late election, and that the Council list was confirmed, the
votes being 166 against 152 in the election for president. The
first paper read was entitled —
A Bunsen Burner for Acetylene,
by A. E. Munby, M.A., and treats of the application of acetylene
gas for heating purposes. It appears that the apparatus employed
is simply an ordinary bunsen burner of special dimensions — five
millimetres internal diameter. It yields a very small jet, and
consumes something like one cubic foot acetylene per hour under
a pressure of six inches water. The heating power is very great,
and Mr. Munby demonstrated the burning of zinc by its means.
It is a flame which cannot be turned low without becoming
luminous ; it is steady and moreover does not strike down. Mr.
Munby is strong in advocating its use in educational laboratories,
as students then require no blow-pipe, and, since it gives twice
the heat of coal gas, there is a great saving of time. The cost
works out very moderately, being only halfpenny per student per
hour. — A paper was next read —
On the Reactions between Lead and the Oxides
of Sulphur,
by H. C. Jenkins and E. A. Smith. It was rather difficult
to follow Mr. Jenkins, who read the paper, as his delivery
was somewhat hesitating. It seems, however, that their work
was undertaken on account of a statement made by Mr. Hannay,
in a paper by him, that an unstable body which he could not
isolate, but to which he gave the formula, PhS.,02, was formed
when oxygen was passed over PhS4 at a certain temperature.
His equation is expressed thus : — 2PhS + 02 = Ph + PhS202. Mr.
Jenkins and his colleague have endeavoured in many ways
to clear up the matter, and they are certainly not in
favour of Hannay’s theory, but they go the length of saying that
Mr. Hannay’s observation was a very natural mistake to make.
Professor Dewar, in fun, said that Mr. Hannay had at least made
an effort to invent a novel compound from his results. Professor
Roberts-Austen and Mr. Groves spoke in laudatory terms of the
work done by the authors. The last paper was by C. T. Heycock,
F.R.S., on —
X-Ray Photos of the Solid Alloys.
His experiments were based upon the fact that in freezing a solution
of potassium permanganate pure ice crystallises out, and the
solution becomes concentrated, and he hoped to get a parallel in
the case of metallic solutions. He has worked mostly on a solution
of gold in sodium. Gold is extremely soluble in sodium, 23 per
cent, going into solution with facility. Sections of the alloy were
out for the X-rays, and Mr. Haycock showed a number of photos
of the results. Sodium being very transparent to the rays and gold
quite opaque, the photos which were thrown on the screen were
extremely pretty, and were convincing enough that Mr. Haycock
had found the parallel he was looking for. — Professor Dewar, who
finished up the discussion on this paper, delivered quite a little
lecture on
Liquid Air,
bearing, of course, on the subject at issue. This was probably the
most generally appreciated item of the evening’s programme.
Royal Institution, Thursday, May 6. — Professor Dewar
-delivered the second of the series of lectures on
Liquid Air as an Agent of Research.
He continued his remarks on the critical constants of gases, and
brought forward some interesting speculations founded on the
extension of certain laws, known by experiment to hold good at
accessible temperatures, to bodies which one can never hope to
be able to examine in the liquid state. Speaking of the theory
that carbon is a very important constituent of the sun, the
lecturer pointed out that the density of the latter is l-4, and
supposing it to consist of carbon at the critical temperature, its
density when cooled to liquefaction would become 4-2 according
to known laws, and if it were cooled to the temperature of the earth
its density would increase by something like one quarter.
Therefore the density of the materials of the earth (which was 5-5)
did not appear to be far removed from the density of the sun at
the same temperature. The rest of the lecture consisted of
experiments to illustrate the capacity of high vacua to retard the
passage of heat. Before concluding the lecture, Professor Dewar,
for the first time in public, froze to the solid state by means of
liquid air a specimen of argon supplied by Lord Rayleigh, the
temperature being more than 200 degrees below zero.
THE WORkD OF PHARMACY.
- 4 - -
BUSINESS MEETINGS.
Chemists’ Assistants’ Association, Thursday, May 6. —
Mr. Charles Morley, President, in the chair.— There was a fair
attendance of members at this meeting, notwithstanding the fact
that the Chemists’ Club annual dinner was held the same evening.
As this was the
Annual General Meeting,
the first business was to appoint two scrutineers to count the
number of votes given to each candidate for the Council, the
gentlemen chosen for the work being Messrs. Smith and Meynell.
— The President moved, and Mr. E. W. Hill seconded, that Mr.
E. J. Millard be accepted as a patron of the Association. Carried.
Mr. C. J. Strother, Treasurer, then presented the financial states
ment for the year, showing an income of £227 11s. 10d. and an
expenditure of £125 19s., leaving a balance in hand of
£101 12s. lOd. He thought this was highly satisfactory, being
the best balance sheet that had been presented for many years.
Notwithstanding the success of the closing session, Mr. Strother
was of opinion they might do better another year if each member
would resolve to introduce at least one new member at the opening
of the session. The membership now stood at 133 and 49 patrons
(one short of the usual number), whereas a few yearsago they had 200
members. He strongly urged that strenuous effort should be made
before next session to increase the membership to 300. He saw no
reason why this should not be accomplished with a little individual
exertion. — Mr. Morley, in moving the adoption of the report,
remarked that it showed a balance to the good which was quite
unprecedented. — Mr. Hill seconded the motion. While it was
satisfactory to note the state of the balance sheet, he thought the
slight decrease in membership was to be regretted, although they
could not hope always to maintain it at one level. One point
worthy of notice was that this year they had a good balance from
the annual dinner, which he thought reflected great credit on the
two secretaries who had the management of it. — The report was
unanimously adopted. — Mr. C. E. Robinson, Secretary, then read
the
Twentieth Annual Report,
as follows : “ The Council has much pleasure in presenting this
the twentieth annual report. Thirty-six new members have been
enrolled during the present session, making a total of one hundred
and thirty-three. The number of patrons stands at forty-nine,
being within one of the limit imposed by the rules of the
Association. Nineteen notes and papers have been contributed
during the session, and in addition a discussion was held on ‘ The
Proposed New Bye-Laws of the Pharmaceutical Society,’ as a
result of which a resolution was carried, and a copy of the same
forwarded to the Secretary of that Society. The average attendance
at the meetings has been well maintained. The annual smoking
concert, conversazione, and series of Cinderella dances were again
a great success, as was the annual dinner at the King’s Hall, Hol-
born Restaurant. In the matter of attendance a record was
established, two hundred and seventy guests having been present.
A Research Prize, consisting of the Association’s medal and
supplementary prize of money and books given by Messrs.
Burroughs, Wellcome and Co., has been awarded to Mr. R. Glode
Guyer for work done on ‘ The Iodine Value of Beeswax.’ The
Council, owing, unfortunately, to there having been no competitors,
has been unable to make the award in the case of the Essay Prize.
424
PHARMACEUTICAL JOURNAL.
[May 15, 1897.
The sum of 15s., proceeds of the sale of programmes at musical
and social evenings, has been subscribed to the Pharmaceutical
Society’s Benevolent Fund. The rooms so long in occupation
at 103, Great Russell Street, had to be vacated on Lady Day, owing
to the fact that the premises at that address were shortly to be
pulled down. Since that time the Association has been temporarily
installed at 9, Queen Square, W.C. The flourishing condition of
the Association from a financial standpoint is indicated by the balance-
sheet, which shows a further increase of balance to the good.” —
Mr. Mobley moved the adoption of the report. He thought it
was a very fair resume of the work done during the session, and was
not expressed in too glowing terms. — Mr. T. Morley Taylor had
much pleasure in seconding the motion. — Mr. Melhuish, in support¬
ing, wished to point out that although they might have been thought
to be very frivolous in holding so many Cinderellas, etc'. , the scientific
papers read at the meetings were of a high order, and had been a
great success. He thought there was a little misconception in
some quarters on that point. Perhaps the reason was that the
Cinderellas had been rather more successful even than in previous
years. — The report was adopted. A very pleasing duty now fell
to the lot of the President, which was to present
The Association’s Medal
to Mr. R. Glode Guyer who, Mr. Morley said, had thoroughly
earned the award about to be presented to him. He was one of those
men who had not allowed rebuffs to prevent him from trying to
secure the medal, which on this occasion was awarded to him
simply because his paper represented better work than any other
sent in. He (Mr. Morley) congratulated him very heartily on his
success. Th6 money and the books from Messrs. Burroughs,
Wellcome and Co. had not yet been received, but they would be
forwarded to him at the earliest opportunity. He had great
pleasure in presenting the medal to Mr. Guyer. — The hearty
applause which followed the presentation showed clearly the high
esteem in which Mr. Guyer was held by those present. — Mr. Guyer,
in reply, said he hardly deserved the kindness he had received at the
hands of the gentlemen connected with the Association during the
five years he had been associated with them, and he was exceedingly
sorry that that would be his last meeting, for he was to leave
London at midnight for the North. When he entered for the prize
he felt that there ought to be a very strong competition for the
award, and he had always wanted to have the honour of earning
it. His paper was not a very big one, but it involved a great deal
of work, and he only hoped the medal had been awarded without
any personal consideration. For all their kindness and the
valuable award he thanked them.
Ball or Conversazione ?
After the applause had subsided, Mr. G. Roe proposed that in
Rule 6 the words “ Annual Ball ” be substituted for that of “ Con¬
versazione.” A long discussion followed, in which most of those
present took part, many arguments being adduced both for and
against the motion. Mr. Roe’s idea seemed to be that it was a sham
and open to misconstruction to call the annual gathering a “ Con¬
versazione,” when it was practically a ball pure and simple, and
that it would be better and give greater satisfaction to those
attending the function, if it were called a ball, dancing
to commence at the time of opening, instead of having to wait
a matter of two hours while a concert or exhibition was being
held to which no one paid the slightest attention, as on former
occasions.— On the other hand it was contended by Mr. C. J.
Strother and others that by calling it a conversazione many non¬
dancing members felt more at liberty to attend, whereas if it
were called a ball they would stay away, and as this was the only
function to which members were admitted free, they would thereby
lose one of the advantages of membership. — As feeling ran rather
strong on the question it was thought advisable to adjourn the dis¬
cussion until an early date next session, fourteen members being in
favour of adjournment and two against.
Result of the Council Election,
The following was the election result, the first fourteen being
elected : — A tie between Messrs. Gamble and Umney was decided by
the President’s casting vote. C. Morley, 51 ; A. R. Melhuish, 50 ;
C. E. Robinson, 49 ; T. M. Taylor, 49; E. W. Hill, 47 ; H. H. Robins,
46 ; C. J. Strother, 46 ; G. E. Pearson, 43 ; T. Tickle, 40 ; F. R.
Stephens, 40 ; G. Roe, 39 ; F. Cooper, 31 ; C. E. Pickering, 27 ;
F. W. Gamble, 26 ; E. A. Umney, 26 ; F. James, 23 ; W. A.
Jones, 21. Some fifty-three voting papers, one informal, were
received after the result was declared, and therefore were not-
counted. — The President then delivered his
Valedictory Address.
Mr. Morley said it was customary on such an occasion to make
a retrospect, in order to show the position in which they stood,
that they might ascertain whether or not the objects with which
their Association was formed continued to be fulfilled. In answer
to this he thought they could reply with a distinct affirmative, as
they had both worked well and played well. The mental pabulum
that had been provided, in the shape of papers and notes read,
had been of a high though variegated order, and had been
met with marked appreciation by members, as shown by the
attendance and interest taken. On the other hand, the social side
of their work had not been neglected ; indeed, suggestions had
been thrown out that to make further developments
of a social character would be detrimental to the interests of the
Association. With that he was quite in accord. At the same
time he would point out that any undue tendencies on their part
in that direction had been more apparent than real, for no more
than the ordinary number of evenings had been appropriated for
social purposes ; but one form of enjoyment had been sub¬
stituted for another. The executive, moreover, had no intention
of making fresh departures of a social nature. In the opening
address which he had the honour of delivering before the Associa¬
tion that session, he made allusion to the fact that, compara¬
tively speaking, so few London assistants were induced to throw
in their lot with them, and he then proceeded to enumerate the many
advantages that were offered to them on joining. He had to con¬
fess to a feeling of disappointment that his appeal to outsiders had
met with such a tardy response, for not only had their member¬
ship roll not been increased but it had shrunk to some slight
extent. To counteract that and to endeavour to make the Associa¬
tion something like a representative one, he now urged every
individual member to do his utmost during the coming vacation to
enlist at least one of his fellows into their ranks. That surely
ought not to be a too difficult task to impose, for there must
needs be a sufficiency of men available who were capable of being
actuated by desires and motives of self-improvement, and
who might be convinced that it was not necessary to go
far afield to gratify those when the Association was
at hand and so well adapted to such a purpose. To
those who wished to be of service beyond their own doors (and
he was sure there were many with such inclinations), before that
end was attainable the essential preparatory lesson of having one’s
self-conceits eradicated and deficiences made apparent could never
be so well learnt as in the attempt at public discussion, nor could
it be begun at so opportune a time as on the threshold of their
more responsible career of mastership. The Council had again to
deplore the fact that the Essay Prize remained unawarded,
but was gratified to think that work had been submitted of
sufficient merit to warrant the bestowal of the Research
Prize. Another gratifying result was the further im¬
proved financial position of the Association. The con¬
tinued augmentation of its funds would, however, have to
engage the serious consideration of the in-coming Council as to
their proper utilisation. In bringing his remarks to a con¬
clusion he came to a consideration in which he was personally very
much concerned. He had such a keen apprehension of his many
shortcomings and disabilities, and he felt that had he not had the
hearty co-operation of their two Vice-Presidents, the two Secre¬
taries, and, in fact, all the members of Council to a much more than
ordinary degree he could not have arrived at a successful issue
with his charge. To them and to all he offered his best thanks.
Halifax and District Chemists’ Association, Thurs¬
day, April 29. — Mr. J. B. Brierley, President, in the chair. — A
largely attended meeting of the Association was held at the
Nelson Rooms, Old Cock Hotel, Halifax, the leading chemists of
the town and district being present.
The Proposed New Bye-Laws
of the Pharmaceutical Society were under close discussion. Clause
11 in Section X. was unanimously agreed to, but great exception
was taken to Clause 17, in respect to the raising of the examination
fee. Clause 18 had the most hearty support of the meeting. — It
was agreed that the President and Secretary be deputed members of
Mat 15, 1897]
PHARMACEUTICAL JOURNAL.
425
the Halifax General Trade Association. — Messrs. Farr and Hebden
duly proposed and seconded that a conversazione be held in
October.— "It was decided that Messrs. Curtiss and Co., carriers,
London, be asked to come into the town to convey
Parcels to and from London,
also that Messrs. Evans, Sons and Co., Liverpool, and Messrs.
Newbery, London, be asked to join the Proprietary Articles
Trade Association.
Pharmaceutical Society of Ireland (Council Meeting)
Wednesday, May 5. — Mr. W. M. Wells, jun., President, in the
chair. — The President reported that a deputation had interviewed
The Governors of the Apothecaries’ Hall,
%
Dublin, in reference to complaints which had been made to the
Council that the Apothecaries’ Hall granted their diploma to
medical men who had not spent a day at pharmacy. The Governors
stated that they would give the matter their serious consideration.
— The President read a letter of the Irish Local Government
Board sanctioning for six months an appointment of Dr. Murphy
and Dr. O’Brien, resident medical officers of Cork Workhouse, to
discharge the duties of apothecary to the workhouse at salaries of
£30 a year to each. The Vice-President remarked that this
was a reversal of a former decision of that Board. — Mr. Kelly
said he had received a letter from a licentiate complain¬
ing of the appointment. — A letter was received from Mr.
Charles Evans, Dawson Street, Dublin, resigning his seat on the
Council. The Registrar was directed to write to Mr. Evans
requesting him to reconsider his resignation. — A letter from Dublin
Castle requested the observations of the Council upon a memorial
which had been addressed to the Lord-Lierftenant by the
Enniscorthy Co-operative Agricultural Society, Limited, requesting
that a fine of £5 which had been imposed on their assistant John
Kinsella for an unauthorized sale of Hayward’s Sheep-dip should
be remitted or abated. The President and Vice-president were
requested to draft a reply to the memorial. — A letter from Mr.
J. C. MacWalter, licentiate of the Society, requested answers to
the following questions: — - (1) whether the Council accepted the
certificates of persons who had served the required four years in
the service of
Limited Liability Companies,
where the debenture shareholders of such companies were unquali¬
fied persons ; (2) whether an unqualified person in the service of
such a company might compound, dispense, or sell a medical pre¬
scription ; and (3) whether the name and address of every person
who being in the service of a limited liability company dispensed,
compounded, or sold a poison or prescription should not appear on
the article. — The President said the Council had never knowingly
accepted a certificate from a limited company, and from what he
knew of several members of the Council he believed they never
■would unless compelled to do so by the Queen’s Bench. — On the
motion of the Vice-President the letter was referred to the Law
Committee with a direction to obtain the opinion of the Society’s
solicitor, and, if necessary, of counsel, as to the answers to be
given to Mr. Mac Walter’s questions. — The President referred to
a passage in a letter of Mr. William Hayes, in which
the writer stated that a certain recommendation of his
had been sanctioned by the Council, with the substitution of the
word “company” for “directorate.” That had reference to what
took place in 1895, when Mr. Hayes, who was then president,
attended in London before a Parliamentary Committee then
sitting to receive evidence in relation to the amendment of the
Companies Act. He submitted a clause to them which had been
appioved of by the Council, but added another which would have
made it legal for a limited company to carry on pharmacy, pro¬
vided they had a qualified “directorate.” Had that clause
passed it wrould have rendered the first null and void. When Mr.
Hayes returned, so far from his action being approved of by the
Council, some members were disposed to move a vote of censure
upon him for having given the Society away, but it was not done
as he was then leaving the chair. The difficulty was got over by
putting “company” for “directorate” in the clause which Mr.
Hayes added ; but the Council never approved of his action in the
matter. A report of a Committee of the whole Council, to which
the question of celebrating the Queen’s Jubilee had been referred,
included a draft address to Her Majesty, which was approved of,
and also recommended that a dinner should take place. It was |
resolved, after some discussion, that in future an annual dinner
should be held. — The Council then adjourned.
Plymouth, Devonport, Stonehouse and District
Chemists’ Association, Wednesday, May 5. — A preliminary
meeting of those members of the above named Association who
propose entering on a summer course of practical botany was held
at the new rooms of the Association, 7, Whimple Street. The
attendance was very encouraging, fourteen members being present,
whilst several others intimated, by proxy, their intention of joining
the class. Mr. Reade explained the following rules, based on sug¬
gestions made by Mr. Holmes, for the guidance of competitors for
the herbarium prizes, viz.
“ 1. The number of plants to be presented by each competitor is limited to
forty.
“ 2. Plants representative of natural orders and illustrative of classification
should be collected.
“ 3. A flower should be dissected and mounted showing the essential organs,
with each Phanerogam ; also the fruit, if obtainable.
“4. In addition to the name of the plant, the competitor should state in his
own language (not copied from text-books) the reason for supposed natural
order and-species.”
After some discussion it was unanimously decided that the class in
Morphology and Classification should be held fortnightly at
8.30 p.m. on Tuesdays, commencing on the 18th inst. The first
ramble of the season was arranged for Wednesday, the 12th inst.,
and subsequently they will take place fortnightly.
NEW REMEDIES.
[ The notes given under this heading embody recent suggestions in
therapeutics. They cover both new drugs and preparations, and old ones
under new aspects. The word “parts” is used to represent parts by
weight, both for solids and liquids.']
Ichthyol as A Laxative. — In the Bulletin Generate de Thbapeu-
tique, Oct., 1896, Gunsburg reports the use of ichthyol in the case of
fifty women suffering from various inflammatory affections of the
genitalia, accompanied by constipation and dyspepsia. The ichthyol
was given in pills of 3 grains once, twice, or thrice a day. The
result was that the constipation was overcome without any colicky
pain or diarrhoea, the appetite improved, and the pain in the
abdomen decreased. As the taste of ichthyol is disagreeable,
Gunsburg suggests that it may be given in keratin-coated or enterio
pills. — Thera. Gazette [3], xiii., 11.
Oxygen in Ascites. — Teissier recommends oxygen according to
Potain’s method in the treatment of ascites by abdominal punc¬
ture, followed by injections of oxygen into the peritoneum. In
the instance under his notice the operation was well borne without
pain or local reaction. The oxygen was easily absorbed by the
peritoneum. For some days there was some gurgling, which dis¬
appeared in a little more than a week. These results were obtained
in three weeks. — Thera. Gazette [3], xiii., 110.
Ointment for Pustular Acne. — Subnitrate of bismuth, white
precipitate, ichthyol, of each, 2 ; vaseline, 20 ; mix. — Rev. de Thcrap. ,
lxiv., 209.
Application for Sycosis. — Mercurial oil, 200; zinc oxide and
starch, of each, 70 ; vaseline, 140 ; ichthyol, 10 ; salicylic acid, 12.
Mix. — Rev. de TMrap., lxiv., 209.
Ichthyol in Erysipelas. — Nabugnow states that with the ich¬
thyol applications, first recommended by Nussbaum, he has been
able to cure 200 cases of erysipelas. The ointment is bound on with
a roller bandage, or in case of facial erysipelas is held in place by a
mask. The following is Nabugnow’s formula : — Ichthyol ammonii,
10 to 20; petrolati, 5; lanolini, 15. M. ft. ungt. — Pediatrics, iii.,
159, after Wratsch.
Guaiacol Valerianate. — Among the many guaiacol esters
which are attracting a considerable amount of attention at the
present time, the valerianate appears to be one well adapted for
medical use. Vogt finds that it is readily taken in doses of 20 centi¬
grammes in gelatin capsules, without causing any disturbance of
the digestion. The author, in fact, took as much as 5 grammes per
426
PHARMACEUTICAL JOURNAL.
[May 15, 1897
diem in this way without experiencing the least unpleasant effect.
It may also be injected hypodermically without occasioning any
inconvenience beyond a slight smarting. When used on dressings
it is readily absorbed if its evaporation be prevented. Given to
twenty-eight tuberculous patients it had a beneficial effect on the
appetite and general health even in small doses. In catarrh, the
symptoms rapidly yielded to this treatment, and good results were
also obtained in chloro-ansemia. Even where the administration
extended from three to five months no inconvenience was noted. —
Jtev. de Therap. , Mid. Chirurg., lxiv., 64.
Potassium Permanganate in Lupus.— Butte states that by the
local application of permanganate, he has effected cures in several
cases of lupus. It is applied in half per cent, to two per cent,
solutions directly to the nodules, and kept in contact with the
surface for ten or fifteen minutes by means of compresses. The
application occasions some pain for an hour, but this is readily
relieved with cocaine ointment. — B.M.J., Epit., 1/97/44.
Salophen in Pruritus. — By the internal administration of
salophen in doses of 4 or 5 grains a day, Wannemarker has
obtained very satisfactory results ; in some few cases it fails, but
in others it gives relief from almost unbearable irritation. —
Epit., 1/97/44, after La Belg. Med.
Ethyl Bromide and Suggestion in Hysterical Aphonia.—
Five cases of hysterical aphonia are reported by Arsslan in which
the patients were rapidly anaesthetised with 10 grammes of the
drug, and as soon as they were fully under the influence of the
dose, it was suggested that they should loudly shout their names,
count numbers, etc. ; the results were satisfactory, and resulted in
recovery.— A. M. J. , Epit., 1/97/36, after Gazz. degli Csped.
Sodium Tetraborate (so-called) in Otorrhcea.— After treating
overa thousand cases of chronic otorrhcea with “sodium tetraborate,”
Kafemann concludes that this salt is by far the most useful appli¬
cation for this troublesome complaint. The salt is prepared by
dissolving equal parts of borax and boric acid in water. On cooling
the tetraborate separates out as a neutral crystalline mass, which,
when dissolved in water, crystallises out again but slowly, so that
50 or 75 per cent, solutions may be used. The liquid is dropped
into the previously cleansed passage, the orifice of which is then
plugged with a pad of sterilised wool. In this way results have
been obtained which are little short of marvellous. — Rev. de Therap. ,
lxiv., 235, after Deutsch. Med. Zeit. [The term “tetraborate” for
this salt is misleading. The true tetraborate of sodium is borax
Na2B4O7-10H2O.— Ed., Ph. J.]
Methylene Blue in Rheumatoid Arthritis. —Methylene blue
seems to be attracting a considerable amount of attention as an
internal remedy. Dr. Philpots has found it to give very marked
relief in obstinate cases of chronic rheumatoid arthritis." He has
administered itin doses of 2 grains afterfood twice daily. Methylene
violet tried in similar cases had very little effect. — B.M.J. — •
1/97/78.
Discomfort from the Continual Use of Saccharin.— Hogarth
concludes that saccharin taken in large doses for any great length
of time may cause acute pain in the region of the stomach and
pancreas. It has before been stated that acute neuralgic pain in
the solar plexus and its region has been produced by saccharin.
A case is cited where pain resembling pancreatic or pyloric colic
supervened after taking six or more saccharin tablets daily for
three and a half years. On discontinuing the saccharin the pain
disappeared. — Brit. Med. Joum., 1/97/715.
Dangers of Thyroid. — Hessler gives an interesting account of
a artificially produced exophthalmic goitre having all the charac¬
teristics of the natural disease, minus the glandular enlargement.
When 75 grains of desiccated thyroid gland were given daily,
symptoms of the above appeared, and the remedy had to be dis¬
continued temporarily, the pulse going up to 160. Hessler con¬
cludes from this and other similar cases that Graves’s disease is
due to an over-stimulation of the nervous system by products of
the thyroid gland, and that therefore its administration is injurious.
— Dublin Joum. Med. Sci., No. ccciii., 276, after Journ. Am. Med.
Assoc.
EXTRACTS FROM CONSULAR REPORTS-
Camphor Exports. — Reporting on the trade of Tamsui (Japan)
for 1895, Mr. Layard states that although nearly 10,000 cwt. less
camphor was exported than in 1894, the enhanced price of the
article, owing to the disturbed state of the island, raised the total
value of the export by some £8000. The quantity exported in 1894
was 33,108 cwts., value £90,149, and in 1895, 23,696 cwts.,,
value £98,905.
Chinese Camphor. — The district round about Amoy, according to
Consul Gardner, is very suitable for the production of camphor,
and it is hoped that the cultivation of the camphor tree will ulti¬
mately take the place of tea-plant culture, which, owing to Indian
and Ceylon competition, is now a failure. The difficulty with
regard to camphor cultivation is that the tree takes long to
mature, and consequently some time elapses before those who
invest in the cultivation get a return for their money. A small
amount was exported last year from Amoy, 157,000 lbs., to Hong-
Kong for transhipment to Europe.
For British Manufactured Drugs, Consul Gardner thinks
there is a good opening in the way of trade in his consular district
(Amoy). The natives, he says, are great believers in medicines,
the medicines most in demand being tonics. Thus ginseng, which
is supposed to be a tonic and aphrodisiac, is annually imported
into the district to the extent of £30,000 sterling. The natives
suffer much from low malarial feveris, and as those fevers generally
yield to quinine, he thinks the sale of quinine might be much
extended. Other common forms of disease are worms, dysentery,
costiveness, and coughs. Neuralgia, rheumatism, and ophthalmia
are also prevalent. To push the sale of medicines adver¬
tising is absolutely necessary, and each bottle or packet of
medicine should be wrapped up in a paper, stating in Chinese the
diseases for which the medicine is a remedy. Vendors of drugs
are recommended to put on the bottles, etc., the price in
“ cash ” at which it is intended they should be retailed, leaving of
course a good profit for the dealer. Forty “cash” equal Id.
There is at present at Amoy one British firm that devotes itself
entirely to selling foreign drugs to natives.
The Trade in Scents and Cosmetics, Consul Gardner also
believes would much increase if British manufacturers would study
the tastes of the Chinese. The first thing to be thought of is
cheapness, and manufacturers would do well to get the
cheapest possible |-oz. and J-oz. bottles of an attractive colour,
like red or yellow, filled with the cheapest possible sort of stopper,
and filled with cheap strong-smelling scent made of, say, coal tar.
The bottles should bear attractive labels, and to facilitate the sale
the bottles should be made in shapes which the Chinese consider
lucky or pretty. Musk and patchouli seem to be the favourite
scents of the Chinese. In the same way there would be a great
demand for lip salve, rouge, and powder for the face, if these were
done up in attractive jars and packages, with attractive labels,
and were saleable at a cheap price.
An Analysis of Trade Gin imported into West Africa has been
made by Mr. G. W. Robertson, F.C.S., A.I.C., at the request of
the Consul-General for the Niger Coast Protectorate, it having
been contended that the quality of the gin was so deleterious as to
be harmful to the persons drinking it. The report is as follows : —
Absolute Alcohol . 39 ’3
Acidity, expressed as Acetic Acid .. 0'0068
Ethers, „ ,, Ether.. 0'02I
Furfural . . ; . !• Present in small quantity.
Higher Alcohols . J
The only alcohol that could be determined quantitatively was ethy
alcohol ; there was no methyl, and the higher alcohols as shown by
Sivalle’s method only existed in traces. The spirit is flavoured by
more than one essential oil, and apparently oil of juniper is one of
those oils. The liquid contains no sugar, and leaves but a small
extract. The liquid is said to consist essentially of pure distilled
spirit with essential oils, but no attempt was made to identify
those' oils in the quantity sent— viz., 632 C.c. The ethers are
returned as ethyl acetate, but from a fractional distillation amyl
acetate was found to be present. It would seem from this analysis
that the trade gin of W est Africa is neither more nor less dele¬
terious than the gin sold all over London.
May 15, 1897]
PHARMACEUTICAL JOURNAL.
427
LETTERS TO THE EDITOR.
The Approaching Council Election.
Sir, — I was surprised to see your excuse in your last issue
for not publishing Mr. Glyn-Jones’ letter re the election of
members of Council. You state that the Pharmaceutical
Journal is not the place in which influence should be exercised
upon the election in reference to matters upon which difference
of opinion exists. Now this is not consistent with your practice
in the past, and I will point out the following
instances. In your issue of May 5, 1889, is a letter signed
by Messrs. Benger, Martindale, and others, asking members
not to vote for Mr. Wills. Again in yours of May 2, 1896,
a letter from Mr. Clower, of Northampton, appeared, asking that
votes should only be given to those who openly declared for the
P.A.T.A., and in yours of April 2, 1897, Mr. Gostling writes sup¬
porting the London candidates, and Mr. Keen, of Bristol, writes in
the issue of April 10. Now it is not fair to give publicity to one side
and not the other. It looks to me as though you had determined
to swamp the P.A.T.A, simply because they aimed to remove some
of the old members of the Pharmaceutical Council who have done
ood work on the scientific side of the pharmacy question, and
ave also at the same time watched the downfall of the drug trade,
and if they will not join hands with the movement now on foot to
help to get better prices and a living profit for their less fortunate
brethren, then they are not our friends and do not deserve our
support.
Sunderland, May 10, 1897. R. H. Bell.
*** Mr. Bell overlooks the fact that in all the instances he refers to the writers were
entitled individually, as subscribers to the Society, to express their views on
the matter in their own journal. Mr. Glyn- J ones, however, wrote on behalf of
an outside body which cannot reasonably be held to have any more right to
interfere in the election than the Anti-Vivisection Society had some years
ago. That interference, it may be remembered, was strongly resented by
the majority of the members and associates of the Society. [Ed., P. J.]
Sir,— The abuse the Council and Society is now passing through
will, I think, have the effect of showing up those who are on its side
and those who are against it, and making its supporters more loyal
and united. I am pleased with your treatment of Mr. Glyn- J ones’
last movement re the Council election, and think it was quite the
right course to adopt. It is out of all reason to ask the members
of the P.A.T.A. to oppose Mr. Carteighe’s election simply because
he refuses to express an opinion.
Chester, May 10, 1897. C. T. Johnson.
Sir, — I think it is a disadvantage not being able to see in the pages
of our Journal the names of candidates for the Council favourable to
the P.A.T.A. As that Association has no hostility towards the
Pharmaceutical Society, and its existence is entirely for the well¬
being of the trade, it is only right that we as electors should know
who are our friends amongst those that offer to represent us. Letters
have appeared upon the merits of candidates before. Why not now ?
As the Journal is the only trade paper I receive, it was only
through the kindness of a neighbouring chemist that the names of
candidates favourable to the P.A.T.A. were made known to me.
May they lose none of the support they are worthy of is the wish of
May 10, 1897. Musca (94/12).
*** Voters who are anxious to obtain information respecting the views of candi¬
dates on particular questions can readily do so by addressing themselves
direct to those candidates. [Ed., P. /.]
A Pharmaceutical Cricket Club for Ladies.
Sir, — As the cricket season has come round again, I beg to offer
a suggestion to the ladies engaged in “the art of dispensing.”
Why cannot we have a cricket club ? The many schools of phar¬
macy have clubs for the male students, but the females are quite
out of it. I am sure the ladies will agree it would be most bene¬
ficial to us after many hours spent in the laboratories. Then we
could have matches against our men students, etc. I hope
sincerely you will allow this to be printed in your columns, as I
am sure the lady students in London will agree with this suggestion.
London, May 7, 1897. Eva Emery.
A Royal College of Pharmacy.
Sir, — Mr. Thomas Greenish’s suggestion in your last issue is
one which should meet with the universal approbation of the
members of our craft. I well remember the day when our thrice
blessed Queen ascended the throne, and her Diamond Jubilee is
almost coeval with my own diamond jubilee in pharmacy. Let
me add my voice as a pharmacist of nearly sixty years’ standing
to that of my colleague Mr. Greenish.
Bradford, May 7, 1897. T. Garratt Forshaw.
Sir,— Mr. Thomas Greenish’s proposition to commemorate the
Queen’s Diamond Jubilee by changingthe title of the Pharmaceutical
Society to that of “The Royal College of Pharmacy” seems to
me an excellent one and worthy of the occasion. I have long
thought that the epithet “ Royal ” ought to come in somewhere.
Only one objection to this change strikes me and that is, that the
contraction for ‘ 1 Members of the Royal College of Pharmacy ”
would be M.R.C.P. , which would clash with the contraction for
“Member of the Royal College of Physicians.” Mr. Greenish
may, however, see a way out of this. W e ought at least to have
“The Royal Pharmaceutical Society,” the contraction in this case
being M.R.P.S., which would be distinctive.
Southport, May 8, 1897. C. F. JespeR.
Sir, — We note with extreme pleasure the suggestion of Mr.
Greenish. An opportunity of enhancing very greatly the prestige
of the Society in the eyes of the public presents itself, and
should on no account be lost sight of. There is no public
body having any pretence to the prefix “ learned” which occupies
a less important position in the public mind than does the
Pharmaceutical Society. Its distinctive title includes the
most cumbrous and awkward of adjectives, an orthoepical
terror to the lay mind. The Society seems to have been singularly
unfortunate in its christening. Contrast for effect and impressive¬
ness on the public mind “Member of the Pharmaceutical Society”
and “Member,” or better still, by far, “Licentiate of the Royal
College of Pharmacy.” The public sadly needs impressing with
the fact that the trained and qualified chemist is something more
than a mere shopkeeper ; and we contend that the free display on
labels and signboards of a title plainly involving State recognition
of the scientific status of the pharmacist, goes a very long way
towards this. Why the Photographic Society, which surely would
hardly assume to itself the importance of our Society as an
educational and scientific body, has just secured this much coveted
prefix, and thus set the “College of Pharmacy” an encouraging
example. We thank Mr. T. Greenish cordially for his excellent
suggestion. The proposal is so palpable a hit, that we trust the
Executive of the Society will not be deterred by the inevitable
sneers of the cynic, but promptly press forward this matter.
Bradford, flay 12, 1897. M. Rogerson and Son.
“Wanted, an Assistant’s Qualification.”
Sir, — I quite agree with Mr. Glass as to the advisability of
splitting the “ Minor examination ” into two parts. If possible,
let a period of six months elapse between the first and second part.
Let the first part consist of chemistry, botany, and physics, and
the second of “materia medica,” pharmacy, etc. A good under¬
standing of the first-named subject is absolutely necessary to a
proper study of those in the second part. Such a division would
to a great extent do away with the prevailing cram-work, and
induce of itself a partial curriculum, a thing much to be desired.
Then we might have the beneficent spectable of men knowing a
little of what they profess.
Leith, N.B., May 11, 1897. Archibald Currie.
Sir, — It seems strange to me that a subject of such vital impor¬
tance to assistants, and more especially to unqualified assistants,
has not yet received the attention of those whom it is intended to
benefit, for so far we have had the views and opinions of employers
only. After a thoughtful perusal of the correspondence and a
further careful consideration of the matter, I have been induced to
send you an expression of my views, which may be of some material
value to the subject under discussion. Whilst I am con¬
vinced, unlike one or two of your correspondents, that both
Mr. McMillan and Mr. Bessant have been actuated entirely by
unselfish and disinterested motives in bringing the matter forward,
I am sorry that I, as one of the unqualified assistants whom these
gentlemen wish to succour, cannot say I have much sympathy
with the proposals suggested. As a rejected candidate at the last
Minor examination, my opinions may be of some worth, inasmuch
as I should naturally then be uninfluenced in my judgment by
bias or partiality in either direction. I do not think any qualifica¬
tion other than the usual one is called for, because I do
not think the present Minor examination a bit too stiff
for anyone who poses as a scientific person, and personally I should
428
PHARMACEUTICAL JOURNAL.
[Mat 15, 1897
prefer seeing the standard raised rather than lowered, because
nothing is worth having unless it costs an effort to acquire, and as
‘ ‘ Saltpetre ” has already pointed out, the higher the qualification
an assistant acquires, the better salary will he be able to com¬
mand. Consequently it should be at once apparent that an
assistant with a cheaper and easily-acquired qualification cannot
expect to be able to command so good a salary. The existence of
such a qualification as that proposed would probably flood the
trade with such qualified men, so that owing to competi¬
tion among themselves they would not be able to command
any better salaries than are at present obtainable by unqualified
men. Consequently the benefit would be all derived by the em¬
ployers instead of the assistants. On the other hand I am informed
by employers that, owing to the dearth of qualified assistants, they
can command any reasonable salary they like to ask for, conse¬
quently the qualification is worth having. If it were easier,
competition among assistants would produce the inevitable result
that there would be a depreciation in value. Although
unsuccessful in my first attempt, I do not despair of even¬
tually passing, and unless other unsuccessful men have
the same expectation, I think they would do well to seek
another vocation requiring less mental exertion. Brains
are required to pass most examinations at the present day, but it is
a moderate amount only that is required to pass the Minor. What
is chiefly required to ensure a successful issue is application and
work, good honest work, and no one has a right to expect success
without it. Instead of advocating a new qualification for assis¬
tants, I think it would be much better policy to agitate for a
written examination, for there is no gainsaying the fact that the
Minor examination as at present conducted is a lottery pure and
simple. I have repeatedly noticed the best of students, medal¬
lists of their colleges, getting ploughed, while students who know
practically nothing take what they familiarly term “their shot”
and are often successful. What I wish to advocate is unifor¬
mity, and that is only practicable in a written examination.
Speaking from my own experience, I can find no fault with the
examiners, as they gave me every consideration in all my sub¬
jects, and how I failed is to me a mystery, as I thought I was
perfectly safe till otherwise informed by the Chairman.
May 7, 1897. Nil Desperan dum (93/33).
Reading by Sir Henry Irving.
Sir, — Will you kindly allow me to announce for the information
of the numerous strangers now in London, and of all interested in
such matters, that on May 31 Sir Henry Irving will read Tennyson’s
‘ Becket ’ in the magnificently restored Chapter House of Canter¬
bury Cathedral for the benefit of the Thirteenth Centenary Fund ?
There will be an exceptional interest in hearing Sir Henry Irving
read Lord Tennyson’s work in the midst of the scenes in which the
memorable death of the great Archbishop took place. St. Thomas
Becket entered the Chapter House on the evening of December 29,
1170, only a few minutes before his murder in the adjoining
“ Martyrdom.” The restored Chapter House will be re-opened by
H.R.H. the Prince of Wales on Saturday, May 29, and will be first
publicly used for the reading which Sir Henry Irving is so
generously to give. After the reading, which will be at 2 o’clock,
opportunities will be afforded to visitors to see the Cathedral and
the very spot where the four knights did their terrible deed.
Specially reserved seats may be procured at one guinea each by
letter to Mr. Crow, Mercery Lane, Canterbury.
The Deanery , Canterbury, May 7, 1897. F. W. Farrar.
A Question.
Sir, — If “ gros” (masculine), in the quotation sent to the Phar¬
maceutical Journal by Mr. Ashton, is equivalent to an English
drachm, what is the equivalent of “ grosse” (feminine) in the same
quotation? “From which it would appear that modern English
pharmacists,” etc. -
Biarritz, May 10, 1897. Enquirer (94/9).
Sweating the Dispenser.
Sir, — In reply to Anti-Sweater’s letter (p. 384), the only
qualification I know of, except those I mentioned, that the
dispenser can obtain without an apprenticeship is that of
Assistant of the Apothecaries Society, and I was not aware that
the Local Government Board would accept that. They would not
three years ago. I have not the slightest idea how many
of the 118 dispensers employed in the poor law service are
egistered chemists, but they must possess some recognised
qualification. As to my ceasing to do extra work, if I told my
Board the work was too much for me, they would very soon tell
me to send in my resignation and let them get some one who could
do it, and there would be plenty of applicants for my post. I
firmly believe the case quoted as to “ how the work is done” is an,
isolated one. I perfectly agree with the remarks on page 319 of.
the Journal, but as long as the dispensers hold a qualification in
accordance with the Local Government Board’s requirements, the-
regulations for keeping open shop do not apply to the case.^ The
only thing to be done is to get the Local Government Board to-
recognise only registered chemists as dispensers.
May 8, 1897. Dispenser (93/43).
The Proposed New Bye-Laws.
Sir, — I heartily congratulate the Council upon the general
acceptance given by the trade to the proposed new bye-laws,
notwithstanding the extra demand made thereby upon the time.-
as well as the purse of aspirants to pharmaceutical honours.
Believing, as I do, that those who are not afraid of study, but
push forward to their full qualification as pharmaceutical
chemists, will not in the long run begrudge either the time or
expense of so doing, may we not hope that as the educational
status of those thus entering the business becomes recognised by the
medical profession and the public, it will be found also that their
support, now too often directed elsewhere, will be transferred to-
the legitimate and responsible body of chemists. I do the more
fully endorse the proposed increased fees, inasmuch as it
coincides to a very considerable extent with a suggestion
I ventured to make in the pages of the Journal many years since,
and I hope that this may be a stepping stone to the further suggestion
I then made, viz., that the increased fees should, on passing the
Major examination, cover registration, not only as pharmaceutical
chemists, but also as members of the Pharmaceutical Society. I
believe that the increased interest in the general work of the
Society would by this means be widely extended, and an encourage¬
ment given to young men to press forward to the higher grade.
The payment of a small annual registration fee by every chemist
upon the Register, as has been suggested recently, appears to my
mind a most legitimate source of revenue, which the Pharma¬
ceutical Society has a right to make in order to cover the expense
laid upon it by the Legislature in the preparation of the compulsory
official annual Register.
Brighton, May 10, 1897. Edwin B. Vizer.
INFORMATION W ANTED.
Hypnotism and Clairvoyancy. — A correspondent asks for the
name of the best work on hypnotism and clairvoyancy (Braidism ?)y
advanced or elementary.
Chromo Prints. — Can any reader give the addresses of firms
who supply the small coloured pictures that are used to ornament
packed goods ? They are similar to those appearing on the small
boxes of wax vestas that are imported from the Continent.
CORRECTION.
Council Report. — Mr. Alfred Woods Saunders points out that
his first name was wrongly printed “Alf reton” in the list of those
to whom diplomas were granted at last week’s meeting of the
Council of the Pharmaceutical Society. The list was printed as
officially supplied to the Journal.
OBITUARY.
Lumley.— On April 15, William Thompson Lumley, Chemist
and Druggist, Kirkbymoorside, Yorks. Aged 80.
Hopkinson. — On April 30, Thomas Hopkinson, Chemist and
Druggist, Grantham. Aged 72.
Moore. — On May 4, John Moore, Chemist anl Druggist, late of
Skipton. Aged 55.
Merson. — On May 5, William Merson, Chemist and Druggist,
Paignton, Devon. Aged 87.
COMMUNICATION S, LETTERS, etc., have been received from
Messrs. Bacon, Barclay, Bell, Bennett, Cocks, Connan, Conroy, Critchley, Cupit,
Currie, Dunning, Emery, Evans, Flatters, Forret, Forshaw, Francis, Gadd, Gart-
side, Gill, Goodall, Haigh, Hansen, Hicks, Higgs, Hill, Howlett, Jesper,
Johnson, Line, Longless, Makins, Marshall, Owen, Penistan, Penman, Pollard,,
Reynolds Ridlington, Rogerson, Saunders, Seely, Smith, Snow, Stanley, Vizer.
[Numerous Answers to Queries are held over.]
Mat 22, 1897.]
IMACEUTICAL JOURNAL.
429
*S> /
BENEY0LBNT Fl)ND FESTIVAL DINNER.
\21 MAY m -S
\ \ . / A
Mr.\W ALT^It y6lLLS, President, in the Chair.
HE Festival Dinner in aid of the Benevolent Fund,
which took place on Tuesday evening at the Hotel
Cecil, was in every way highly successful. Upwards
of 300 members and friends of the Pharmaceutical
Society were assembled in the good cause. The
amount of donations announced exceeded the most favourable
anticipations. The dinner was well served, the speeches were not
too long, and the pleasure of the evening was greatly enhanced by
the admirable vocal music of the Meister Glee Singers.
The guests were arranged at a cross table, presided over by the
President, and seven spur tables, presided over by Messrs. G. S.
Taylor, E. N. Butt, R. Hampson (Treasurer), John Harrison
(Vice-President), Charles Umney, W. Martindale, and C. B.
Allen. Amongst those present were the following : —
W. Arkinstall, H. R. Arnold, J. J. Arrow, S. R. Atkins, A.
Proctor Atkinson, L. Atkinson, Dr. J. Attfield, H. F. Austin,
Rev. G. Baetz, R. R. Bainbridge, A. Baiss, J. A. Ball,
F. Bascombe, H. Bate, T. H. Bateman, J. Bates, T. Bate¬
son, J. W. Bessell, F. E. Bilson, H. C. Birch, F. C. J. Bird, Stan¬
ley Bird, C. A. Blake, H. Bolton, jun., H. N. Bolton, A. Bottle,
I. Bourdas, G. S. Boutall, J. W. Bowen, A. Boyes, F. W. Branson,
R. Bremridge (Secretary), R. Harding Bremridge, T. Brewis,
G. E. Bridge, A. J. Brown, C. J. G. Bunker, H. T. Butler,
J. Butterworth, D. Calder, J. F. Cantwell, M. Carteighe, R. W.
Carter, J. W. Castle, J. H. Chaplin, A. J. Chater, J. A. Clark,
J. Clarke, H. Collier, A. Cooper, A. J. B. Cooper, J. Cooper,
J. A. Cope, H. Cracknell, F. Cresswell, H. Davenport, T. Davies,
T. H. Dewey, R. J. Dodd, Dr. Dowding, F. Durant, W. B. Dyson,
G. Eade, E. J. Eastes, — Elkington, J. G. Everett, J. Laidlaw
Ewing (Chairman of Executive, N.B. Branch), — Fitzgerald,
A. Flack, J. Floyd, C. W. L. Flux, T. G. Forshaw, J. Foster,
G. Bult Francis, W. H. Francis, Dr. Frankish, J. H. Frost,
Dr. A. W. George, W. S. Glyn-Jones, G. Goldfinch, W. L. Golds¬
worthy, W. H. Gooch, T. Green, Professor H. G. Greenish,
T. Greenish, W. Gregory, E. H. Grimwade, Hon. S. F. Grim-
wade, N. M. Grose, W. F. Gulliver, F. Guy, F. W. Hamilton,
S. B. Hardcastle, J. F. Harrington, R. K. Harvey, R. M. Harvey,
J. H. Heap, K. Hebbeler, — Hertz, J. Hewlett, E. J. Hill, J. Ruther¬
ford Hill, Dr. R. Hills, C. Hodgkinson, G. A. Hodgkinson,
J. Holding, T. C. Holford and Friend, E. M. Holmes (Curator),
W. M. Holmes, W. King Hopkin, F. G. Howe, C. T. Howse,
E. A. Hugill and Friend, J. H. Hugill, J. Humphrey,
H. 0. Huskisson, J. C. Hyslop, T. H. W. Idris, J. Ince, S.
Ingall, Adpar Jones, G. E. Jones, N. C. Jones, H. Kemp,
G. A. Lansdown, Dr. A. Lapworth, Dr. H. Leins, R. Leng, F. H.
Lescher, D. L. Lewis, J. E. Lidwell, W. Lincolne, J. Lloyd
and Friend, W. L. Longstaff, J. Lorimer, E. W. Lucas,
P. MacEwan, E. R. Marsh, J. G. Massey, Charles Martin,
T. C. W. Martin, J. H. Mathews, A. J. Mayjes, H. Moon, C.
Morley, A. Morson and Friend, T. P. Morson, H. Moss, J. Moss,
W. A. H. Naylor, J. Neale, G. T. W. Newsholme, T. Nicholls,
V. Norman, R. S. Page, R. Pain, C. J. Park, W. Parsons,
Dr. B. H. Paul, W. Peacock, E. Peck, D. Peters, E. Pettinger,
A. J. Philips, W. J. Pinchen, T. E. Polley, Dr. W. G. Potter, Major
Vol. LVHI. (Fourth Series, Vol. IV.). No. 1404.
A. C. Preston, C. Pretty, Col. Clifford Probyn, W. R. Pryke, F.
Ransom, D. Rees, W. I. Richardson, J. Robbins, W. Roberts,
C. E. Robinson, J. Robinson, R. A. Robinson, W. P. Robinson,
F. A. Rogers, W. J. Rogerson, H. W. Royle, C. Rundle, Ryman,
A. L. Savory, A. Saxlehner, W. C. Sayers, John Selley, A. Shillcock.
H. D. Simpson (Mayor of Louth), Adams Smith, Rev. A. 0. Smith,
C. B. Smith, P. J. Smith, A. H. Solomon, S. L. Stacey, E. B.
Stamp, J. C. Stead, G. G. Stickland, W. H. Stickland, E. H.
Storey, F. Sutton, Dr. C. Symes, A. E. Tanner, J. W. Taplin, R.
Taubman, G. S. Taylor, S. Thompson, J. J. Thorn,
T. Tickle, F. W. Truman, J. C. Umney, A. C. Vallance, H.
Walker, W. P. Want, J. S. Ward, A. W. Waring, F. W.
Warren, W. Warren, F. W. Warrick, A. J. Watson, C. Webb,
H. E. Webb, H. S. Wellcome, S. J. Weston, T. J. Whiffen,
W. G. Whiffen, R. L. Whigham, E. White, Dr. Percival
White, J. Harrop White, W. Whitehead, H. Wiggins, A.
Wigginton, Dr. H. Wilbe, W. W. Will, H. Williams, W. Lloyd
Williams, G. S. V. Wills, A. J. Wing, J. A. Wink, E. P. Wolff,
Hermann Woolley, W. Woosnam, A. C. Wootton, G. W. Worfolk,
J. R. Wretts, A. Wright, H. C. Wright, R. Wright, and J. Rymer
Young.
Thetoastsof “The Queen”and “The Prince and Princess of Wales
and the rest of the Royal Family ” having been duly proposed and
enthusiastically received, the President gracefully alluding to the
Diamond Jubilee in regard to the first toast, and in the second to
the benevolent efforts of the Prince of Wales in connection with
the London hospitals,
The President again rose, and said : The toast—
“Prosperity to the Benevolent Fund”
is undoubtedly the toast of the evening, and is one which will be
received by this company with the utmost sympathy, even though
the speaker who offers it for your acceptance lacks the eloquence
which the subject deserves. Perhaps the first thought that arises
in our minds is one of regret that there should be necessity for
such a Fund, and if we could ensure the realisation of our wishes,
we might prefer an alternative toast, “Success to all Chemists.”
General experience, however, reminds us that failure is not
peculiar to our calling, and that in every profession and trade
there are those who through misfortune, want of ability, or want
of wisdom, are unsuccessful, and need for themselves or for their
families a helping hand. I think it will be generally admitted
that in all such cases, when the circumstances of relatives and
personal friends do not make it possible for assistance to be sought
in that direction, it is the duty as well as the privilege of those who
follow the same occupation to furnish the help that is required.
And there is a bright side that we must not overlook, and one
which I should like to emphasise on the present occasion. It is
this, that the need for such a Fund calls forth our sympathies and
supplies a theme which unites us more closely together than any
other of our common interests ; and we would not willingly
dispense with anything which constantly reminds us that “we are
brethren.” For brethren we are, in spite of the fierce competition
430
PHARMACEUTICAL JOURNAL.
[May 22, 1897
of modern commercial life, a competition which promises to
become more extreme as time goes on and population increases.
Well is it that we should in every way endeavour to encourage a
better preparation for life’s battle in all who are entering our
calling ; well is it that we should insist upon wider general
knowledge and sounder technical training ; still, there will be in
the future, as there have been in the past, failures, calling for the
assistance which our Benevolent Fund was established to render.
I feel that I am addressing a very sympathetic audience. I know
that all present are friends and supporters of the Fund, and that
there is no need to speak at length about the methods of
its administration and the good work it has accomplished.
But it is a fact of common knowledge that the names of the larger
proportion of registered persons are still absent from the list of
donors and subscribers, and it is to these that I would make a
special appeal for co-operation. How is it that so many hold aloof
in this matter? It cannot be on account of the cost of administra¬
tion, for I venture to affirm that there is no fund which is
distributed with less deduction for such expenses. When you
consider that if you give £1 towards this Fund, something like
19s. 9 d. gets to the person who needs it, I think it says a great
deal for the way in which it is managed. It cannot be because
the benefits of the Fund are confined to a too limited area,
for help is extended in the most catholic spirit, alike to subscribers
and non-subscribers, to members of the Society, and those un¬
connected with it. It cannot be because there is ignorance as to the
existence of the Fund, for to every one on the Register informa¬
tion respecting it is frequently supplied, and personal appeals are
constantly made by our Local Secretaries and others. Is it possible
that some of our friends still think that by subscribing to the
Fund they are helping to support a society with the
general aims of which they are not in sympathy ?
If so I would ask them all in earnestness to divest themselves of
this idea, and realise that the Fund exists for the benefit of all
registered persons, and that every case of necessity receives the
most sympathetic consideration. The subscriptions and donations
of the more wealthy members of our calling are very acceptable,
but the small gifts of the less well-to-do are valuable too, not only
because they add to the amount available for distribution, but
also because they furnish a gratifying indication of a personal
interest in the furtherance of an object which should command
the sympathy of all. As you are all aware, the Benevolent Fund
was founded more than fifty years ago, and relief is given either
in the form of annuities or as casual grants. For the former over
£2000 is now annually required, and this considerable sum is more
than double the amount derived from interest on invested capital.
The remainder, together with all that is needed to furnish
the casual grants, must be supplied by subscriptions. These
casual grants are given after full consideration of each case
by the Committee, and often enable persons to tide over
periods of distress or illness with good permanent results.
As regards the candidates for annuities it is only necessary to read
the short accounts of their age and circumstances as furnished on
the voting papers to be assured of their extreme and painful need
of assistance. The Council is constantly receiving grateful letters
of acknowledgment from those whose last years are made more
endurable by these annual grants. A few details respecting the
Fund may prove of interest. Since 1868 the large sum of £46,800
has been distributed — £33,554 in the form of annuities, and £13,246
as casual grants. In 1868 the annuities amounted to £190 only,
and the casual grants to £121. Since that year there has been a
steady advance, culminating last year in £2232 for annuities and
£563 for casual'grants. Subscriptions during the same period have
risen from £551 to £1739, and interest on investments from
£274 to £1051. Last year the total amount given was £2795,
and the total income was £2790 — £5 less than was expended.
Since the establishment of the Fund there have been 130 annuitants,
and at the present time there are 45, nearly all of whom receive an
income of £50. This is the fifth Festival Dinner at which special
efforts are made in support of the Fund. Later I will ask the
Secretary to be good enough to read the list of the larger dona-
ions received on the present occasion. To all who contribute, our
thanks are due — and I mention with gratitude the efforts on
behalf of the Fund made by our Local Secretaries and others.
Special efforts have been made at Glasgow, Liverpool,
Nottingham, Northwich, and other centres — and particu¬
larly at Manchester, where our indefatigable Secretary, Mr.
Kemp, has been able to collect no less a sum than £114.
Now, gentlemen, I think I have detained you sufficiently long.
You all know what good work this Benevolent Fund is doing, and
I am quite sure that you wish that it may continue to do that
good work, and that it may always have plenty of money to do it,
if that money is required. There are many subjects on which we
have differences of opinion, whether in ordinary politics or in
pharmaceutical politics, but I am sure we are all of one mind in
this matter, and desire to help those of our brethren who are in
trouble and distress. We may differ on many things, but we are
all at one in the cause of charity.
In faith and hope the world will disagree,
But all mankind’s concern is charity :
All must be false that thwart this one great end,
And all of God, that bless mankind or mend.
Mr. Martindale next proposed the toast of
“ The North British Branch,”
referring to the prudence and foresight with which the affairs of
the Society in Edinburgh were managed by the Executive, and
coupling with the toast the name of Mr. J. Laidlaw Ewing, the
Chairman, on whom he thought had fallen the mantle of the late
John Mackay.
Mr. J. Laidlaw Ewing, in response, said the North British
Branch included so many individuals and bodies that if he were to
attempt to speak for them all he would have to detain the company
for an inordinate length of time. With regard to the Executive
over which he had the honour to preside, he might say that it was
something like the Council in London, only it had the semblance
of authority without the reality, but at the same time it escaped
the fierce light of criticism which beat on the more august
body in London. Having briefly referred to the Board
of Examiners in Scotland, and the regret they felt
at having to send so many candidates empty away,
he alluded to the efforts of the Local Secretaries in Scotland on
behalf of the Fund, which they considered not only a duty, but a
privilege. It was sometimes said that there were very few Scotch¬
men on the list of applicants ; if so, it was probably due to the fact
that one trait in their character was “to keep a close grip on the
bawbees ” ; but at any rate, they were all members of one Society,
and ought all to unite in the practice of one of the greatest of
human virtues, a virtue which was practically unknown to the
great nations of antiquity, that charity' which was twice blessed —
blessing him who gave and him who received.
The Vice-President next proposed the toast of
“The British Pharmaceutical Conference.”
Probably most present belonged to that body, but if there were
any who did not he should advise them to reconsider their position,
and join a body which was doing such remarkably good work for
May 22, 1897]
PHARMACEUTICAL JOURNAL.
431
pharmacy in Great Britain. He was quite sure there was need of
some organisation to promote better union among pharmacists, for
he could well remember in his own town how difficult they found
it to secure unity of action on matters affecting their common
interests. As a former President used to say, “ they were like a
rope of sand.” He was happy to think, however, that through the
exertions of the Pharmaceutical Society, assisted by the Con¬
ference, they were getting a little more united, which was a
benefit, not only to those who joined the body, but to all concerned.
He looked upon the Conference as very largely the handmaid of
the Society in this respect. The Society was restricted by Act of
Parliament, but the Conference was a perfectly voluntary body,
and could take up work which was beyond the scope of the Society,
and he believed could do it well. During the present year they
were to meet in the second city of the Empire under the presi¬
dency of Dr. Symes, and he hoped and believed it would be a more
successful gathering than any which had yet been held.
Dr. Symes, in reply, said for many years he had advocated that
every member of the craft should be a member of the Pharma¬
ceutical Society, and that evening he wished to add that he should
also be a member of the Conference. The esteem in which the
Conference was held was evident from the cordiality with which
the toast had been received. Still, they were occasionally met
with the old question of cui bono ? but the answer, he thought, was
quite easy. They should consider the social and intellectual
advantages which accrued from the meetings, and also the fact
that those who could not attend received a valuable Year Book,
which contained matter of interest and importance to him in his
daily life which far exceeded the small annual subscription, and
was always useful to anyone who was making his living in phar¬
macy. It might be said that in these days of competition it was
impossible to live by pure pharmacy, but he contended that it was
out of pharmacy that a man did make his living. If such
were the case it was evident that even from a selfish point of
view the opportunity should not be lost of joining a body
and assisting a movement which helped to develop the art in
which they were all interested.
Mr. Atkins next proposed the toast of
“ The Visitors.”
He said this year there were fewer visitors than usual, this being a
Decennial Dinner for the express purpose of raising funds for the
Benevolent Fund, and, therefore, men of eminence outside their
own ranks had not as usual been invited. There were, however,
this year an enormous number of visitors in England from all parts
of the world who came to take part in our rejoicings, and to see
the priceless institutions of this little island which had broadened
down from precedent to precedent until those who lived in it were
thankful and proud of their position. Both in literature and in
science they could show an unparalleled development in the
history of the world, but above all he trusted that our visitors
from abroad would find that characteristic which he thought
might justly be claimed by England, that righteousness which
exalted a nation. He coupled with the toast the name of the Hon.
F. S. Grimwade, a Member of the Upper Chamber of the Legisla¬
tive Council of Victoria, whose father he knew years ago, and
whose name had stood high for two or three generations, both
socially and commercially.
The Hon. F. S. Grimwade felt it a great privilege to be present
on that occasion. Some sixty years ago he remembered being
introduced by his father to Jacob Bell, the prince of pharmacists,
and he was very proud to be seated by the side of the present
President of the Society, who was the head of the historic firm of
Jacob Bell and Co. When he was over here twelve years ago, Mr.
Carteighe, the then President, received him with great hospitality,
and showed him over the School of Pharmacy in Bloomsbury
Square. He congratulated the Society on the admirable School,
Museum, and Library which it possessed, and said he always felt
a great confidence when as a wholesale man he was sometimes
asked to send assistants to take up positions 2000 or 3000 miles
away in being able to send a man who had studied at
that School or passed the examinations of the Society.
Not only that, but he had sent both his sons there to obtain a
thorough training in pharmacy, and he was glad to say they had
now been his partners for some years, and were giving a very good
account of themselves and the training they had in England.
Although he had lived in Australia two-thirds of his life, and his
wife, children, and grandchildren were all Australian born, he still
felt it was the proudest distinction that he was a Britisher. Im¬
mense progress had been made during the sixty years of Her
Majesty’s glorious reign, but in no respect had the advance
been greater than in pharmacy. The ranks of pharmacy now
contained many men distinguished in science, highly-educated
gentlemen in every sense of the word, and he only hoped as time
went on pharmacists would be true to themselves and respect
their profession. He hoped the Society would continue to prosper,
and prove even more useful in the future than it had in the past.
Amount Received for the Benevolent Fund.
The Secretary, at this stage of the proceedings, read out the list
of donations and subscriptions (see pp. 451-452), and said the total
amount received or promised was £1925 9s. , only £75 short of £2000.
The President, amidst great enthusiasm, announced that his
friend, Col. Clifford Probyn, had kindly intimated to him that he
would increase his donation from 10 guineas to 100 guineas, in
order that the 2000 guineas might be made up.
Mr. Brown, of-Greenwich, also announced that he would increase
his donation from 5 guineas to 10 guineas.
Mr. A. L. Savory next proposed the concluding toast,
“The Health of the President.”
He said no one who was not a member of the Council could1.,
appreciate the enormous amount of hard work which fell upon the
shoulders of the gentleman who held that office. It was by no means *
a sinecure, and he was sure they would all welcome Mr. Walter
Hills in his present position. He had all the qualifications
needed for a President, good sense, good judgment, patience
and tact, and took a deep interest in the welfare
of the Society. They would all wish him the same robust health
which was possessed by their past President, Mr. Carteighe, and
as successful and long a tenure of office.
The President, in responding, said Mr. Grimwade told him there
was a sort of bye-word in Victoria that the Scotchman got all the;
money, the Irishman had all the billets, and the Englishman had to
do all the work, and with regard to his predecessor, Mr. Carteighe,
he claimed to have some Irish blood, and, therefore, possibly that
was why he got the billet for fourteen years, but he was bound to say
that he had also done an immense amount of work. At the close
of his first year of office he must acknowledge how much he was
indebted to his predecessor for the help he had rendered him, as,
he was also to the Secretary and all the senior members of the,
staff. He was glad they had had such a successful evening. The
Fund had profited by a record amount, and they might all feel
pleased at the result. He did not propose to speak about pharma-,
ceutical politics, as he should have an opportunity of saying a few
words about them on the following day. He thoroughly appre¬
ciated the cordial way in which he had been received.
432
PHARMACEUTICAL JOURNAL.
[May 22, 1897
PHARMACEUTICAL SOCIETY.
MEETING OF THE COUNCIL.
WEDNESDA Y, MA Y 19, 1897.
Present :
Mr. Walter Hills, President.
Mr. John Harrison, Vice-President.
Messrs. Allen, Atkins, Bateson, Bottle, Carteighe, Cross, Gost-
ling, Grose, Hampson, Martindale, Newsholme, Park, Savory,
Southall, Symes, and Young.
Several members were restored to their former position on the
payment of the current year’s subscription and a nominal fine.
The_Council then adjourned to the Annual General Meeting.
THE ANNUAL MEETING.
The President took the chair at 12 o’clock, and the Secretary read
the notice convening the meeting. The Annual Report and accounts
were agreed to be taken as read.
The Chairman said : It has been the custom for many years
at these meetings for the President to move the adoption of the
annual report. The arrangement has the great advantage of
giving him, as the mouthpiece of the Council, the opportunity of
filling in details between the lines of the report, with the result
that time is often saved in the subsequent discussion. I have now
attended the annual meetings for over twenty years, and I well
remember how, under the old arrangement, the adoption of the
report was moved and seconded by prominent and eloquent
members not on the Council. Perhaps it is natural for me, on this
my first appearance in the capacity of President at an annual
meeting, to refer for a moment to one such occasion, the annual
meeting of 1874 — the first over which my late uncle presided. I
feel that I have some excuse for directing your attention for a
moment or two to a meeting held twenty -three years ago, because
the subject of education, which I consider to be the keynote of the
report now presented to you, was also very prominent on that
occasion. It is interesting to note that towards the end of the
meeting Mr. Atkins, who was not then a member of Council, and
who had previously moved the adoption of the report, moved : —
“ That the Preliminary examinations of the Pharmaceutical Society of Great
Britain be discontinued after the year 1876, and that the certificates of
legally constituted examining bodies be accepted in lieu thereof.”
This motion was not put to the meeting, but a short discussion
ensued, for the subject was at that time receiving considerable
attention. Although the transference of the conduct of the ex¬
amination to the College of Preceptors was made two years later,
it has been left for the present Council to endorse in the amended
bye-laws the motion tentatively put forward at that meeting.
The report of the Council submitted to the same meeting re¬
ferred at length to the important changes in the conduct of the
School of Pharmacy carried out during the previous year. These
changes were, broadly, the severance of the intimate connection
which had hitherto existed between the Council and the School,
and the commencement of shorter courses of instruction. In both
these particulars the older arrangements have recently been
revived, with modifications, by the present Council. And no w,
gentlemen, I propose to say a few words with reference to some of
the paragraphs in the Report now before you.
The Financial Position.
I must confess that I am not at all depressed as to the financial
position of the Society, about which much has been written lately.
I am not one of those who think that the primary object of a Council
such as ours should be to save money and make investments for
the benefit of posterity. In my opinion the first aim should be to
spend as much as is available on all objects which are desirable or
beneficial to the whole body. You are all aware that during the
last few years a considerable portion of our income and some of
our invested capital has been spent both here and in Edinburgh
for the purchase of premises and for the erection and equipment
of buildings better adapted for examination and other purposes
than had previously been available. The money for this, as well
as for the provision of new offices, Council and Committee rooms,
ttc. , in London, has, I think, been wisely spent. It has enabled
us to transact our business with greater convenience than
before, and has afforded more room in the older buildings
for other important and growing departments of our work.
The report says that “ it is satisfactory to note that the anticipa¬
tions of the Council with reference to the reduction of the balance
on the Journal account have been well founded, and it is confidently
hoped that the improvement will be continued.” You will notice
that this balance, which, exclusive of postage, was in 1894 £1471,
and in 1895 £2761, has in 1896 been reduced to £2229, and I have
no hesitation in saying that I believe that at the end of 1897 there
will be a further considerable reduction. I may mention paren¬
thetically that the specially large sum debited to the Journal in the
1895 account was fully explained twelve months ago by my pre¬
decessor, whose hopeful anticipations on that occasion with regard
to the Journal have been since fully realised. I think you will
agree with me that our Journal is now quite up-to-date, and sup¬
plies a large amount of useful information to its readers. I am
glad to know that in its present form it is much appreciated and
widely read, with a corresponding value both to advertisers and to
proprietors. Whilst speaking of the J ournal, I should like to say
that, in estimating the cost at which it is supplied to each member,
it is necessary to bear in mind that about 400 copies are given away
weekly to honorary and corresponding members, public institu¬
tions, etc. In this way the Society is doing public work by pro¬
moting the diffusion, amongst the intelligent classes of the commu¬
nity, of knowledge respecting the history and prospects of pharmacy.
Too much importance must not be attached to the figures relating
to fees and the expenditure in connection with the School, because
they cover a time of transition, and therefore are somewhat
deceptive. A large proportion of the students’ fees received in
1896 will be paid out during this .year, but I believe that the future
cost to the Society of the School and the Research Department,
under present arrangements, will be considerably less than during
the last few years. As regards the examinations I have nothing
special to say, except a word of regret that such a large proportion
of candidates failed to satisfy the examiners. Should our amended
bye-laws come into operation, I think the percentage of failures
will be reduced.
The Council and the School.
I propose to speak later about the amended bye-laws,
and I therefore pass on to the paragraph headed “Council.”
It seems strange, no doubt, to you, gentlemen, as it certainly
does to me, that Mr. Carteighe is not occupying this chair
to-day. At fourteen consecutive annual meetings he has pre¬
sided, and for fourteen years he has ungrudgingly devoted his time
and abilities as President to the welfare of the Society. Our
special thanks are due to him for this, among other proofs, of his
loyalty and devotion to our corporate interests. Mr. Schaeht’s
death so soon after his retirement from the Council was a matter
of the profoundest regret to his colleagues and friends.
Having regard to the life, work, and' character of our de¬
parted friend, I think you will agree that it was desirable
to make this special allusion respecting him in our Report.
I pass over the paragraphs relating to the museum and the library,
not because of their unimportance, but simply because the informa¬
tion respecting them is of the usual character, and does not call
for special comment. The important alterations arising from the
reorganisation of the School, which, I believe, have been generally
approved, are working well. We have a large number of students
taking the elementary course, and next year we hope to have a
larger class for the advanced course, mainly composed of those who
are at present taking the elementary course. The extension of
these courses will doubtless be of great advantage to the student,
and the close connection restored between the Council and the
School by the appointment of a visitor from the School Com¬
mittee is also satisfactory. The retirement of Professors Attfield
and Dunstan and of Mr. Ince, who have for different periods been
associated with our School, furnishes us an opportunity of
recording our thanks for their past services and of express¬
ing our good wishes for their continued usefulness and happiness.
I am sorry that grants for the encouragement of provincial education
are not given more frequently. Too often local associations, which
have a fair beginning, undergo a gradual process of disintegration
under the depressing influence of apathy and indifference, but all
requests for help are carefully as well as sympathetically con¬
sidered. As regards the research department of our school, in case
there should be any disappointment that there are at present no
published records of completed investigations, I may say that work
in that direction is being done, and that I hope in due course
May 22, 1897.]
PHARMACEUTICAL JOURNAL.
433
useful results will follow. It must be remembered, however, that
research is a lengthened process, and cannot be done to order ;
also that one of the objects contemplated by the establishment of
this department was to teach our advanced students the method of
research. I trust that after the expiration of our Major course in
1898 several students will find it practicable to work for some time
in the research laboratory.
Pharmacy Act Proceedings.
It will be noticed that a large number of infringements of the
Pharmacy Act have been dealt with by the Council ; most of them
were of the usual somewhat monotonous character. As a rule
when cases are brought into court south of the Tweed, we have no
cause to complain of any want of sympathy on the part of County
Court judges with our object to enforce the conditions of the
Pharmacy Act, but in Scotland there is a considerable difficulty in
carrying out the provisions of the law. It must be remembered
that, under the Pharmacy Act, registered chemists and druggists
and medical practitioners are allowed to carry on business for the
sale and dispensing of poisons, and that the interpretation of the
Act has, unfortunately, placed limited companies outside the
scope of its provisions. It has also been decided in the Divisional
Court, by Mr. Justice Hawkins, that each sale of such poisons
must be made by the hands of a registered person. It follows,
then, that on the premises of chemists, medical men, and limited
companies alike, proceedings under the 15th Section can only be
taken against the unqualified individual by whose hands the sale is
made, and who is, in many cases, from a moral point of view the
less guilty' person. I regret that such is the case, but, as far
as I can see, there is no other method of procedure ; and this
condition of things sometimes induces an apparent sympathy
on the part of sheriffs and others with the unqualified assistant
against whom proceedings are taken. This sympathy is shown by
the ridiculously small penalties that are imposed and the costs that
are allowed, and also by the general tenor of remarks made
during the conduct of the cases. This was very marked during
the hearing of cases brought recently before Sheriff Mair at Airdrie,
these being cases of sales of poisons by the unqualified assistants
of medical men. In giving judgment the sheriff is reported to
have remarked: — “ It was Said by the prosecutor that these pro¬
ceedings were taken in the public interest. On the contrary, he
had a very strong suspicion that behind all this some private
interest, of which they knew nothing, was involved.” And later,
“I do not see why these professional witnesses should be sent into
this district to trap the doctors’ assistants and bring them here
for punishment, and to mark my disapproval of the action of the
Pharmaceutical Society in this matter, and my condemnation of
the proceedings in these cases under the Pharmacy Act, I will
inflict a nominal penalty of 2s. 6d. on each of the defendants,
with 2s. 6 d. of expenses.” Now, with reference to this I should like
to state that it is not thecustom of the Pharmaceutical Society to seek
out cases of infraction of the Pharmacy Acts. Reports are made
by our local secretaries and others that on certain specified premises
or in certain specified districts the lav/ is being disregarded.
These reports are brought under the notice of the Council, whose
duty it obviously is to take serious notice of such statements. In
order to obtain evidence it is necessary to procure purchases of
oisons, and, having regard to the natural reluctance of neigh-
ours to appear in any subsequent proceedings, it is often unavoid¬
able to employ persons called by the sheriff ‘ ‘ professional wit¬
nesses.” This is not altogether a satisfactory method, but it is
the only practical one, whilst the difficulty of procuring evidence
is also enhanced by the fact that persons who are knowingly
breaking the law are often very chary in supplying poisons to
strangers. The points which I wish to emphasise are these : — 1.
That it is the duty of the Pharmaceutical Society to take proceed¬
ings against all persons who are infringing the Pharmacy Acts.
2. That proceedings are taken against the unqualified assistants of
registered chemists equally with those of medical men and com¬
panies when the sale# of poisons are not under the required super¬
vision. 3. That in many cases, as I have previously indicated,
proceedings are only possible against the person who actually
hands over the poison. It is to be hoped that before long it will
be found that the assistant who has been fined will discover that
there is a remedy provided by the law, and that he will succeed in
obtaining compensation from his employer. I must once more pro¬
test against the unwarranted assertion that “some private interest
is involved,” and I repeat that the Council, in proceeding against
these persons, is only carrying out statutory obligations. If in
thus doing our duty and protecting the interests of the public the
advantage is on the side of qualification, it is only what is just and
what is in accordance with the spirit of the Pharmacy Act. With
regard to the amounts of penalties awarded, it is unsatisfactory
that in Scotland, where the proceedings bear the character rather
of a criminal than of a civil character, sheriffs have the power of
inflicting merely nominal fines. The extreme smallness of the fines
and of the expenses frequently allowed, together with the considera¬
tions to which I have already alluded, “increase the difficulties of
carrying out the provisions of the Pharmacy Act north of the Tweed.”
The case Society v. Fox, alluded to in the Report, is of great
interest, but I will not detain you now with any remarks on the
subject of patent medicines further than to say that the Council
continues to carefully watch the applications for patents in order
to prevent the granting of any which, in their opinion, have no
claim to a right to be so protected.
The Importance of Education.
It is unnecessary to speak about the Benevolent Fund, as>
I had occasion last evening to refer at some length to this
important branch of our work, and I am rejoiced to think
that such a substantial addition to the Fund was made at ofir
Festival Dinner. The North British Branch is working
loyally and harmoniously with the Council, and I desire to
thank the members of the Executive of the Branch for the care
and judgment with which they look after our interests, and
especially my friend Mr. Ewing, the Chairman, whose loyalty and
devotion it is impossible to over-rate. We regret the loss of all
whose names are mentioned in the obituary paragraph. Our rolls
of honorary members, corresponding members, former members of
Council, iocal secretaries, and divisional secretaries are each
the poorer by the deaths of those whose names are recorded.
Before I conclude I should like to repeat that I consider educa¬
tion in its widest sense to be the prominent feature of the Report
before us. That Report seems to imply that according to the
opinion of the Council the best weapons for the pharmacist of the
future with which to combat the difficulties that beset his pro¬
gress are, firstly, a liberal general education, the test for tho-
possession of which is provided for in our amended bye-laws, and-
secondly, together with apprenticeship or pupilage, a sound tech¬
nical training, such as is now provided by the lengthened curri¬
culum in the Society’s School. But as in the moral world there
are sins of omission as well as those of commission, and as there are
critics who overlook neither, I should like further to say that, as
far as I know the opinions of the members of the Council, they are
quite prepared to apply for Parliamentary powers to consolidate the
Society by the election to membership of all chemists and drug¬
gists. It is necessary, however, to remind you that failures of
previous efforts in this direction have been largely due to the Want
of unanimity and energetic support which are required to carry such
a Bill through Parliament. It is not possible to create any outside
publicinterest in thesubject, and there wouldbe considerable difficulty
in getting a department of State to take it up. It is all the more
necessary, therefore, that evidence should be afforded to the in¬
coming Council of a very general desire that such a change in the
constitution of the Society should be effected, and that, should a
Bill dealing with it be presented to Parliament, our friends through¬
out the country should with no uncertain voice make their wishes
known to the members of Parliament of their respective districts.
In this, as in all other changes which the Council may from time
to time consider to be beneficial for all who practise pharmacy, it
is well to remember that unless we are ready at times to sink
individual differences for the common good, very little progress can
be expected. On the other hand, if we take as our motto “ Union
is strength,” we may confidently expect that many of our aspira¬
tions for the advancement of pharmacy may in due time be
realised. I now beg to move that the Annual Report and State¬
ment of Accounts as published be received and adopted.
The Vice-President : I rise with great pleasure to second the
motion. I do not propose, after the very lucid, careful, and
eloquent exposition which the President has given of the Report,
to add at this stage any further words to it.
Mr. Atkinson : From the general disinclination there appears
to be on the part of members to make observations on the
Report, I gather I shall be giving expression to the general
feeling, that it will be desirable to limit remarks to the smallest
possible compass, and that limitation I take to be in order
that we may have more time to devote to the business of the day
434
PHARMACEUTICAL journal.
[May 22, 1897
which is to come on subsequently. Nevertheless I do not think
we ought to allow it to pass by without some recognition. The
reorganisation of the Pharmaceutical Society’s School I believe to
have been a very arduous work, and that you should have succeeded
in reorganising the School and getting it all into nice working shape
during the recess reflects the greatest possible credit on everyone
concerned. I believe that the changes which you have made will
meet with general acceptation. I think they are almost too obvious
to require comment, but broadly speaking you seem to have given
about double the amount of time to a large number of very impor¬
tant subjects, and I can conceive that that is a very great advan¬
tage, not only to the students but to the teachers, and I believe
that we shall reap the benefit of it hereafter. I would just like,
as briefly as possible, to call attention to something I consider of
importance, and that is the condition of the
Poison Schedule.
I think I may take it that since the passing of the Pharmacy Act
over thirty years ago, there has been but very slight alteration
indeed in the condition of the Poison Schedule, and when we take
into consideration the enormous advances that have been made in
medical therapeutics, and side by side with that the
•enormous number of new remedies that have been
added to the pharmacist’s armentarium, I think it
is quite time there was some alteration made in that respect.
I am not bitten very severely with the carbolic acid
question. I know that the Pharmaceutical Society have made
representations with regard to the sale of carbolic acid, and
similar representations have been made by other societies and
from various other sources, but, considering the variety of uses
to which carbolic acid is applied, I doubt very much whether you
would ever persuade the Privy Council to place such restrictions
on its sale as would confine it absolutely to the custody of regis¬
tered chemists and druggists. I believe if you put pressure on,
the condition of affairs might be something like this, that you
would have certain regulations made which might have the effect
of breaking down those broad distinctions which the public recog¬
nise between the way in which we handle these things and the
way in which they might be handled by ordinary persons. I do not
think, therefore, in the interests of the trade, it is necessary to take
some very active steps with regard to carbolic acid. The things
I have in mind more particularly are many of the new synthetic
preparations ; for example, sulphonal, antipyrine, exalgin,
phenacetin, and cocaine, the last especially. I think the law in
relation to the sale of medicated wines is simply in a chaotic state.
It is very difficult to approach the Revenue on any of these sub¬
jects, but it does seem to me very anomalous that a qualified
chemist should be compelled to put into his coca wine with a full
quantity of alkaloid an additional quantity of extracted matter or
•foreign matter, which may make it extremely unpleasant,
whereas anyone who takes out a licence, either a grocer
or provision merchant, can sell anything he may call
coca wine, which may have the minimum quantity of
medicinal value and the maximum quantity of any kind of
alcoholic trash, which it is a libel to call wine. I think you might
with great advantage direct your attention to this matter. I will
not detain you longer, but I think it is a subject which the Council
are competent to grapple with.
Mr. Glyn- Jones : There are just a few remarks I should
like to offer, which appertain really to the conduct of the
Society’s Journal, and before doing so I should like to know
whether the question of what appears in the editorial columns of
the Journal is placed unreservedly in the hands of the Editor, or
whether it is subject to a Journal Committee. I should like to
know that before addressing my remarks, as it may have some
bearing on what I have to say.
The President : I think I may answer Mr. Jones by saying it
is unreservedly in the hands of the Editor. Of course his conduct
is always open to criticism and may be brought before the Council,
and the Council would take due notice at any time if they thought
the Editor had either overstepped his duty or fallen short of it.
Mr. Glyn- Jones : I am exceedingly obliged to you, sir. I do
not know why I should have had the impression, but I have had
it, and I think the answer you have given will clear up a little
misconception which existed not only in my own mind, bu t in
that of many other adherents of the Society. There is an idea
that the conduct of the Society’s J ournal is mainly in the hands
of a general committee. However, the question I have to bring
before you is this. As most of you are aware, a letter was sent to
the Pharmaceutical J ournal, with a request that it should be inserted
in the issue of May 8, dealing with the Council election. I am anxious
not to say one word as to the character or work of any organi¬
sation or association on whose behalf that letter was written ;
I am here as a private member of the Society to offer at any
rate my own humble protest, and I think the protest of many others
connected with us, that that letter was not allowed to appear in the
Journal of the Society, the more so because on turning to the
Journal I found there that the Editor had been good enough to
explain to the readers why this was done. He said that it had
always been held that the Journal was not the place in which
influence should be brought to bear on the Pharmaceutical Council
election. As to whether he held that as being judicious or wise
I have nothing to say, and had the facts borne out that statement,
then I take it those of us who were interested in having that letter
appear had no cause of complaint. But on looking through past
copies of the Journal, we found letters have appeared dealing
distinctly with the election, and we also found that individual
candidates have been selected and the voters have been asked
to vote either for or against such candidates. That took
place, as you know, some years ago. Then, again, last
year letters were inserted with the object of influencing
the election, and in this very election we have letters
appearing there seeking to influence the candidature of London
members as against those who live in the country. I am not for
one moment arguing whether it is wise we should have London
members, but I do maintain that it is a question of opinion, and
that those gentlemen who live in the country who are seeking seats
on the Council had quite as much right to think they were eligible
for the Council as those who live in London. I am not at all
objecting to those letters appearing, but what I do strongly pro¬
test against is that the slightest partiality should be shown by our
Journal. I know it is necessary that we as chemists and drag-
gists should be exceedingly loyal to our Society, and I appeal to
those who know anything about my own views, publicly expressed
in meetings of the trade throughout the country, when I say that
no one is more anxious that the Pharmaceutical Society should
receive the unanimous support of the trade than I am myself.
But if that is to be done then freedom of criticism and freedom
of opinion must be allowed.
The Pharmaceutical Journal.
We are always told, is our Journal, and of late years efforts have
been made to make it a trade journal. Now if that is so, is it not a
suicidal policy on the part of the Society, who wish to make it a
trade journal, to shut out of it letters which come not from Glyn-
Jones, but from a chemist and druggist who represents 2000
chemists and druggists in business, between 1400 and 1500 of
whom are members of this Society. Those members wished to
bring certain things before their fellow-members, and I think it
is most natural they should conclude that their Journal was the
proper place in which that should be done. On some of the
members of the Society writing and complaining of this conduct,
we find that a new ground has been given why this letter was not
inserted. We find that the reason given formerly does nothold good.
That has been shown to be a weak argument ; it has been proved
that letters have been admitted, so that we are now told that this
was not written by a private member of the Society, but by a
person representing a society which has no more to do with the
Pharmaceutical Council elections than the Anti-Vivisection
Society. Now, gentlemen, I earnestly wish to put this before you.
It has been recognised all round that the Pharmaceutical Society
as such cannot deal with certain trade matters, and no one has
been more anxious to put that before the trade than I am myself.
I constantly go amongst men who say “ I will not support the
Society because they do not do this for me, and they do not do
other things,” and I have tried over and over again to show them
how, tied as the hands of the Society are by the Pharmacy
Act, it is impossible for them to do that, and therefore there was a
necessity for a certain organisation to deal® with trade matters.
That organisation sought to have men on the Council who were
in sympathy with us in these trade questions. Whether
the Pharmaceutical Council itself is to deal with the
subject does not touch the question. There can be no
doubt that the Pharmaceutical Journal showed some few
months ago that ideas of the Council of the Society are
changing. Those in the rank and file of the trade are glad that
change is being made. The Journal some months ago said the
time would come when we should recognise that the attainment of
pure high-class pharmacy was a myth practically — that is what it
May 22, 1897]
PHARMACEUTICAL JOURNAL.
435
amounted to. We are glad to see there are men on the Council
who are at any rate imbued with that idea, men who are anxious
to do all they can for the education of the craft, and, on the other
hand, feel keenly the wants and needs of those who are struggling
in business. We are glad to see those gentlemen there, and we
want to see more of them. It is, perhaps, invidious to mention
names, but there are men on the Council such as Mr. Park, of
Plymouth ; Mr. Allen, of Kilburn ; and Mr. Grose, of Swansea ;
and others who take a keen interest in these matters. We want
to see more of such men there, and I think we have
a right to express our opinion and say so through the
Journal that that should be done. We did not ask your Editor to
say for us what we wanted to say ; it would have been quite
right that the Journal should have inserted that letter, and then
that it should have shown how ridiculous it was if that was the
opinion of those who conducted the Journal, and if it could be
shown that we had no more right to interfere than the Anti-
Vivisection Society. But I press upon you gentlemen, if you are
to receive the support of the trade, then anything which is being done
for the good of the rank and trade must be talked about in some
other tone than that of saying it has no more right to touch the
Pharmaceutical Council election than that of the Anti-Vivisection
Society. There are many who judge your attitude by that expres¬
sion alone, they will say, “Yes, when we try to do what the
Council admit they cannot do for us we are told we are practically
to them what the Anti-Vivisection Society is.” I have said
enough, gentlemen. I do not wish to move that the report be not
adopted on this ground, but I do think this was the time to men¬
tion it, and I hope that in future the Council, or rather, perhaps,
our Editor, will see to it, that at any rate the columns of the
Journal are open impartially to every member of the Society.
Mr. Hambrook (Dover) : It is a great many years ago since I
was here, when the Society was on a very small basis. It has
broadened out since, and I am very anxious that it should broaden
more. I was very glad to see that the Council had it in their minds
to elect all associates in business to be members of the Society.
I think you have shadowed that forth at the end of the Report, and
I hope to live a little longer to see it carried out.
Mr. Wiggins : I have come here to support the Council in the
excellent bye-laws which they propose should become law. First,
I will take the raising of the Preliminary examination -
The President : I am delighted to hear you, but if you would
confine your remarks to other portions of the Report and leave your
remarks with regard to the bye-laws to the special meeting it
would be more convenient.
Mr. Wiggins : I thought we were at the special meeting.
The President : No, we are at the annual general meeting.
Mr. Percy Wells : I think, sir, you have heard my voice here
before, whether to your satisfaction or otherwise I leave you to
reply. I do not come here to-day to criticise
The Action of the Council
either for or against, because from my previous experience
I find that, notwithstanding all promises that are made before
election, somehow or other when these gentlemen get inside
the Square there is a kind of shadow comes over them,
and they gradually drop down to the normal condition
of things which is peculiar to Bloomsbury Square.
Then they say, if we come here and have our annual
grind at them what is the use ? They seem somehow or
other to belong to the order of what is called pachydermata — they
are absolutely impenetrable. But there is some one subject which
I have come here to talk about to-day, and only that, and that is
a matter which at the present juncture ought to appeal to the
feelings of every chemist, and that is £ s. d. Now, sir, there is no
doubt in my mind, looking at this matter frqm a business point of
view, that your expenditure is exceeding your income. Last year
you borrowed £1500 to carry on, and you paid that off when your
revenue came in, but then, again, you know you had to borrow
£1500 again, and that money is still owing and the interest
.accruing. Of course, I never gave the Council credit for being
thorough men of business.
The President : I might put Mr. Wells right to this extent,
that the £1500 is not owing.
Mr. Wells : It appears on the balance sheet as owing.
The President : For last year.
Mr. Wells : We will not quibble about that now, sir. I am
going to prove that you are not men of business, and I make that
statement boldly, and without any reservation or hesitation, and
I also accuse you of what I would call in the politest language not
suppressio veri exactly, but the suppression of facts that ought in
common justice to be laid by you before your constituents.
Remember, if you please, you as a Council are only trustees, and
that you are bound morally, I maintain, and legally, to render a
full and faithful account of your stewardship. Now what have you
done ? What do I find here ? Expenditure under the head of
Journal — Journal balance of account in one line £2228 Is. 9cZ. , and
instead of following that up with the other expenditure con¬
nected with the Journal of £875, nearly £900 for postage, you put
it some distance down. Now you know that is not quite a fair
way of doing things. And even the Editor of the Journal the fol¬
lowing week, on May 15, I suppose being worried a little by the
protests of members of the Society who have seen through the
thing, sees fit to write under the head of
The Dual Function of the Pharmaceutical Society
some wretched explanation, at least I suppose he calls it an
explanation, of the items. He endeavours to prove too much,
or rather he endeavours to prove such a little, as shows me
he is not by any means a man of business. He may be a very
good professional man, he may be acquainted with all the
oologies in creation for what I know, but when he comes to put his
pen to paper about £ s. d. he is nowhere. Now, sir, I maintain
you are acting unfairly, unjustly, and unwarrantably. I will not
recall a single word— in simply saying to us this is the balance to
the debtor of the J ournal account. What we want to know, and
what we have a right to know and insist upon (that is, if chemists
have the moral courage to make you), is the total expenditure con¬
nected with the Journal. We used to have it. We used to
have the cost of printing ; we want to know what you pay your
Editor and Sub-Editor ; because please to remember — take any
journal you like, take the whole lot through the year, certainly a
great part of it is waste paper ; but I take the lot simply for the
purpose of reference, and I have kept them ever since 1840, and I
may tell you furthermore, not caring twopence for your index, I
have indexed them myself. I have a fairly good memory for
figures. Some time ago you gave your Editor £500 a year, and
your Sub-Editor I think £250. Now we have a right to know
whether that remuneration is continued, or whether it is increased.
You do not tell us what the printing of the Journal costs; you
enter into no explanation of how much per page or anything of
the kind. We are kept in the most perfect ignorance. That is
not right ; it may suit your policy, but it does not suit
ours. I appeal to these gentlemen present and ask them
whether they are satisfied with the present condition of things ?
If they are, I am very sorry for them. Now, with regard to the
ability of the Editor, what do I find ? When I look through the
Journals I find the editorial portion is of the most minute
character, in fact, I would do the whole lot myself, I would just
write the same copy — that is what it is called — every week in half
an hour, and give myself time to spare, too. Take the whole lot
of the Journal, and what is it ? It is what is called in the trade —
not in our profession — scissors and paste, nothing else. Anybody
could do it.
A Member : Do not be so insulting.
Mr. Wells : I am not ; I hope I have not insulted anyone.
The President : I am sure Mr. Wells will try to keep from
personalities, and in giving expression to his own opinion I am
sure he will bear in mind that others have characters and reputa¬
tions at stake as well — in matters of opinion I mean.
Mr. Wells : I have not attacked the reputation of anybody.
I am addressing you as I have been accustomed to for many years
of addressing the President. I am speaking of the Editor of the
Journal. I began about the Editor, and I am referring to him ;
if you like I will call him Dr. Paul, but that would be personal.
A Member : Stick to the £ s. d. part — not the literary part.
Mr. Wells : If scissors and paste is literary work, then I have
for nearly seventy -three years lived in vain. It is a matter of
£ s. d., and costs money. I know what I am speaking about, and
I will keep to the point. All this stuff, as I call it, the proceedings
of some little coterie or other which meet together to have a dinner
or fgo out to cricket or golf, or something or other — how in the
name of patience does , it interest the majority of the readers of
the Journal ? [“ Of course it does.”] Well, then, if it interests the
majority, I am very sorry ; but it does not interest the minority
represented by the speaker who has the honour of addressing you.
I maintain that you would make the Journal more interesting,
more educational, and reflect more credit on the Society if you
[May 22, 1897.
436 PHARMACEUTICAL JOURNAL.
would just take out about two-thirds of what I call the twaddle
which is to be found in it.
A Member : Make Mr. Wells Editor.
Mr. Wells : No; Mr. Wells does not consider himself suited
for an Editor. There is another matter I want to speak about. I
see two sums of ten guineas— one under the head of “ Library,”
and the other under the head of “Museum.” It is peculiar that
the expenses of these two officers should exactly come to ten
guineas. Surely they are in receipt of their salaries while they are
attending the meetings referred to in this balance sheet, and may I
ask how long was the time occupied in attending the meeting and
the expense that was incurred ? Please to remember that these
are paid officers, and the time they are attending these
meetings is the time you pay them for their services.
Then, again, I maintain if they are put to any expense in
going to and fro, you are perfectly justified in paying them for
that, and for that only. Now wall you permit me in conclusion—
I know that has an exceedingly pleasant sound — to say that I
hope for the future you will, as you ought to do, take those for
whom you are trustees into your confidence, and that you will put
out in extenso, if you do not choose to put it in the balance sheet,
then in an appendix to it, the total detailed expenditure connected
■with the Journal, and I hope by this time next year, by curtailing
the chaff that is in there and only giving us the wheat for our
food, the cost of the Journal will be materially diminished. I
thank you, sir, and through you the members present, for their
courtesy in listening to me, with some pleasing interruptions.
The President : If no other gentleman has any remarks to
make with reference to the Report, I should like to say
one or two words with reference to the speeches to
which we have listened. In the first place, I should like to say
how delighted we are to see one of the founders of the Society
(Mr. Hambrook) here, and we hope he will live a good many years
and see some consolidation of the Society. With regard to Mr.
Atkinson’s remarks, I thank him for the confidence he has ex¬
pressed with regard to the general policy of the Council, and
especially with reference to the School. As regards
The Poison Schedule,
that matter is constantly under our notice, and we will bear
in mind the remarks he has made to-day. I come now to Mr.
Glyn-Jones’ speech. I would repeat that Dr. Paul, in my judg¬
ment, is responsible Editor of the Journal. We give him a con¬
siderable amount of rope, and we believe that our confidence in
him is deserved. If we think that he has made a mistake
we shall tell him so, but with regard to this special matter
to which reference has been made, I am not prepared to
say he has made a mistake. I think, broadly speaking,
the point is this, that it is open to any member of this
Society to send a letter to the Editor with reference to a
coming election, and provided there is nothing libellous in it
he may expect that that letter will be inserted, as a member or
associate of the Society who signs his name ; but if any combination
of persons sends a letter, and that combination may consist of
members or associates of the Society, or some who are not
connected with the Society, or a mixture of the two, then I think
it is quite open to the Editor to say that he does not think it is
wise to insert that letter. I myself should go a step further, and I
rather deprecate myself any letter that says “ Do not vote for a
man.” By all means show up a man’s good qualities, and say why
you think he is deserving of support, but I am not very much, I
confess, in favour of any expression of opinion which says that a
man should not receive support ; however, that is matter of opinion.
In this particular I think Dr. Paul has done what I should
have done myself. Now, Mr. Percy Wells has spoken
at considererahle length to-day; we are delighted to see
him in excellent health and up to his usual form, but I must
confess that at the end of his remarks I am not very much wiser
than I was when he started. He has expressed a great many
opinions, but I do not think they have been based upon fact. He"
says he could write a better editorial, or he could do it in a very
short time, but he has also said there is a good deal of waste paper
on which the Journal is printed. He has also informed us that he
has taken the trouble to index it. It is a pity I think to index
waste paper. With regard to these little items of expenditure,
representing the cost of the production of the Journal, I maintain
that the Council is elecied by a number of members and associates
who have confidence in that Council when once elected. Whatever
Mr. Wells may say as to our want of ability or our possession of it,
I believe that the members and associates of the Society have con¬
fidence in us, and that we have a fair amount of business capacity,
and I believe that it is in the interest of the Society and
of the Journal that the figures he asks for should not be given.
For what purpose do you require to know the exact income of Dr.
Paul or of the Sub-Editor ? Have you not confidence in us that we
should do the best we can for the members of the Society, and also
what is just to the Editor and Sub-Editor ? Then with reference
to the ten guineas for the Curator attending some meeting in the
country and the Librarian — it was the express wish of the Council
that those officers should attend those meetings, and would Mr.
Percy W ells like to see that the expenses were £9 4s. 3d. , or would
he like to see that ten guineas is given to deserving persons, and
even if they may be out of pocket or they may not have spent it
all, is that a matter worth consideration here ? We think, as
business men, it is the right thing to give what we consider a fair
amount to cover the expense of a visit to a meeting which we have
asked them to attend. I do not think there is any other point to
which I need allude, and I will therefore now put the motion.
Mr. Stacey : Before you put that, if I am in order, I should
like to say a word. I understood Mr. Wells to appeal to the
Auditors, and if he did so I shall be quite prepared to make some
remarks if the meeting wishes it.
The President : I do not think he did. I will now put the
resolution : —
“ That the Annual Report and Statement of Accounts be received and
adopted.”
The resolution was carried with one dissentient.
Mr. Stacey : I should like with your permission to make one or
two remarks as to
The Position oe the Auditors.
I believe it is not clearly understood by this Society what position the
Auditors hold, and I believe that gave Use to the remark of an appeal
to the Auditors. I noticed also in the J ournal last week, in a leading
article speaking of the balance of the J ournal account, £2200 odd,
the statement that “ these figures are correct, for they have been
vouched for by the Auditors. ” Those figures are perfectly correct as
matter of income and expenditure in the office of the Society, but the
Auditors do not vouch for any inference that you may draw from
those figures. Our duty is a very simple one, it is a hardworking
one ; but we are very careful not to infringe on the duties and respon-
sibilitiesof the Council itself. A gentleman called this thing, which he.
held in his hand, a “balance sheet,” this is not a balance sheet..
I was on the Council about thirty years ago, and I have been an
Auditor now for thirty years, but I have never seen a balance sheet of
the Society. I think it is important that the members should not be
misled in that respect. The books of the Society are most beautifully,
neatly, and correctly kept. This is merely a statement of the actual
income and expenditure. We check every figure and we vouch for
its being correct. This is a list of the property of the Society, which
we carefully go through every year and see that it is in the Society’s
possession. We have nothing whatever to do with the valueof it.
We simply go upon facts. The Auditors have sent to the Council,
and annexed to the report this year a request, which they sincerely
hope the Council will carry out, which will be largely to the benefit
and advancement of this Society in placing the accounts in a more
business-like and material form.
The President : Is there any other business to bring before the
annual meeting ?
Mr. Campkin : May I ask one question, if I am in order ? I
intended to do so earlier, but I was under the impression that the
Report would be taken first and the accounts afterwards. I am
following now the remarks of Mr. Stacey with regard to the
accounts. If no sufficient statement of accounts is given with
regard to the Journal expenditure, how is it that we have had,
during the past three months, some very liberal statistics given
with regard to it ? There must be some account published that
has enabled those who have criticised the accounts of the Journal
to make the statements they have done with regard to it, that is,
with regard to its financial position from 1868 up to now, and the
deficit from time to time has been explained. I have gathered from
information that I have been able to obtain, that during the past
28 or 29 years the Journal has undoubtedly shown an adverse
balance in the aggregate when the amount of postage to members
is added thereto ; but we in the country have been led to believe
that the Journal has cost considerably more in the aggregate
than the amount of our subscription as members. From an inves¬
tigation of these accounts some of us have come to the conclusion
that those statements are not founded entirely on fact, and that,
in fact, the members’ subscriptions have not been infringed by the
Mat 22, 1897]
PHARMACEUTICAL JOURNAL.
437
amount of one-half. Further, we have learnt that a statement
of the receipts and expenditure has been given to the Council
year by year in connection with the Journal, and from that
statement I have gathered that roughly for the past twenty-
nine years the excess of expenditure over receipts has amounted
to what, on the average, would make the cost of the
Journal to the members something between 7s. and 8s. per
member, leaving a balance of Us. or 12s. in favour of the Society.
If I am correct in that and if I have been able to elicit those facts,
I would submit that there must have been some publication of
accounts in connection with the Journal, and therefore it is rather
an erroneous impression that there are no means available to
■obtain this information. I am afraid if I were to go into further
particulars I should weary you. There are other matters
in connection with the Society one would like to have spoken of,
but knowing there is to be a special meeting, which will afford us
further opportunity of speaking on the general work of the
Society, I refrain from further troubling you. After what has
taken place during the past two or three months with regard to
the J ournal I think some full explanation, following that which
appeared in the Journal of May 5, might be made by someone
connected with the Council. We have been told it is the unwritten
law that remarks from “Members of the Cabinet ” at such meetings
as this is not usual ; that the meeting is left more particularly to
the individual members. That may be right, and so far we have
acquiesced in that, but at the same time those of us who live at a
distance do come to the annual meetings for information with
regard to the Society, and when we have elicited that information
it is not for ourselves alone but the whole pharmaceutical body, for
hey are put in possession of it throu ^h the medium of the various
journals.
Appointment of Scrutineers.
The President then read a list of names of gentlemen who had
been nominated to act as scrutineers, and their appointment was
unanimously agreed to.
Appointment of Auditors.
The following gentlemen were appointed to act as Auditors
Butt, Edward Northway, 77, Hamilton Terrace, London, N.W.
Lescher, Frank Harwood, 60, Bartholomew Close, London, E.C.
Stacey, Samuel Lloyd, 22, Great St. Helens, London, E.C.
TJmney, Charles, 50, Southwark Street, London, E.C.
Yates, Francis, 101, Southwark Street, London, S.E.
The President then called attention to the fact that the follow¬
ing Registers had been laid upon the table in compliance with the
provisions of the Act : —
‘ Register of Members, Associates and Students of the Society.’
‘ Register of Pharmaceutical Chemists.’
1 Register af Apprentices and Students under the Act of 1852.’
‘ Register of Chemists and Druggists under the Act of 1868.’
Mr. James Mackenzie: I should like to make some observations
on the motion of which I have given notice.
The President : Before we go to the special meeting, I am
willing to hear you with regard to your motion. As far as I see,
this motion of which you have given notice is hardly in order.
The first portion of it is a pious expression of opinion about which
I am quite willing to hear you make any remarks you choose, but
with regard to the second part of your motion it seems to me it
is not competent for this meeting, and would be out of order
altogether to resolve what you propose there, seeing that we
have, as the legislative power, agreed to refer for confirmation the
amended bye-laws, and the special meeting is going to deal with
those bye-laws. It is going either to confirm them or send them
back ; therefore it would be obviously out of order for any meeting
to say that the bye-laws are not called for at the present time. I
am quite willing to hear Mr. Mackenzie on the first part of the
motion.
Mr. Robbins : May I venture to suggest that Mr. Mackenzie’s
attitude would be all right if he speaks at the general meeting in
the sense of the motion of which he has given notice. He will
then have an opportunity of saying that he thinks the bye-laws
should not be confirmed.
The President : It would be better if Mr. Mackenzie reserved
his remarks till the special meeting. I will give him any oppor¬
tunity of speaking, subject to the ruling of what can be put and
what cannot be put at that meeting.
Mr. Mackenzie : I stand here by right that as a member I am
entitled to bring forward a motion at this meeting provided that I
give due notice of it. Am I to understand that I may only put
this motion in part or wholly according to your suffrage ?
The President : I understand that all meetings are so far under
the control of the Chairman for the time being. Every member
and every associate of this Society has full power and right to
come here once a year and express his views at any reasonable
length, but I think it is the right of the Chairman for the time
being to say what he thinks is in order and what he thinks not in
order. Mr. Mackenzie has given notice of a resolution, which I
have duly put on the notice of this meeting, but I rule at this
stage of the proceedings that the second part of his resolution is
out of order. If he likes to speak to the first part as to great
improvements in the constitution, powers, and working of the
Society being required, I am quite willing to hear him now. His
opinion may be seconded, and it may be more or less of an abstract
resolution. I fail to see how it can have any great weight unless
it is carried, but even then it is only an expression of opinion that
will go on to the Council.
Mr. Mackenzie : I am sorry to take up the time of this meeting,
but I thought my resolution was the most business-like form to put
it into in order to bring into review the whole case, because I am
old enough to know what the Chair can do, and that it might have
ruled that the point I raised was not competent to be raised ; but
I believed, by giving notice of the motion, I could not make it so.
On the question of the bye-laws I am quite willing to leave the
approval or non-approval to the special meeting, but it must be
clear to all of us that it would not be competent for me to speak
at the special meeting on the point that 1 wish to speak at this
meeting, because the special meeting is called for a special
purpose. I have been waiting for the Chairman to refer to this
point, or I would have spoken earlier.
Mr. Carteighe : It seems to me that the President is bound to
allow every member of the Society to give his reasons why the
bye-laws should not be confirmed. You, I presume, will object,
and I would simply suggest that you should divide your observa¬
tions into two parts.
Mr. Mackenzie : I am quite willing.
The President then declared the meeting adjourned until
Thursday.
THE SPECIAL GENERAL MEETING.
Immediately after, the adjournment of the Annual Meeting on
Wednesday, the Secretary read the notice convening the special
general meeting.
Mr. Carteighe said : I move formally : — •
“ That the sections and bye-laws which are now before the meeting be taken as
read collectively and individually.”
This having been seconded, was put and carried unanimously.
The President : I beg to move : —
“ That the fourteen bye-laws of the Society, numbered 11 to 24 of Section 10, be
abrogated, and that the new bye-laws now submitted to this meeting be con¬
firmed.”
In offering this resolution to you, gentlemen, I should like to make
one or two remarks. In the first place, as you all know, there are
two principal points with which we deal in
The Amended Bye-Laws.
The first point is that with reference to the conduct of the First
examination, which it is suggested should be discontinued after
June, 1900, and that registration as an apprentice or student as a
necessary condition before entering for the qualification examina¬
tion should be contingent upon the production of certifi¬
cates of general education granted by an approved examining
body. Now that, of course, is a very important altera¬
tion. We propose that in future there shall be a test
provided in this way to prove the existence of a more general
and more elaborate education on the part of those who are about
to enter our calling. With regard to that point I may say that,
as far as I can judge, the feelings of the members and associates of
the Society and others who have spoken at the different meetings,
there is almost absolute unanimity that this is desirable. There is
another point which is dealt with in these bye-laws, and it is this,
that the fee payable by candidates for the qualifying examination
should be increased to ten guineas. On that there has
been some little difference of opinion, but not, as far
as we know, officially, or very little. I have had
the pleasure of reading to the Council resolutions passed
at different public meetings throughout the country, all of
which resolutions have been absolutely, as far as they were worded.
438
PHARMACEUTICAL JOURNAL.
[May 22, 1897.
in favour of the whole scheme contemplated in these amended bye¬
laws. There has been only one jarring note as far as I know
officially, and that jarring note has been a letter which was sent to
the President of the Pharmaceutical Society by Mr. Wootton.
You all know the contents of that letter, gentlemen, and with
reference to that I should like to say that there is objection, of
course, by Mr. Wootton to this second point to which I have alluded ;
but in that letter he gives a specific reason for his disapproval and a
sort of general reason. With regard to the specific reason of his
disapproval, I think it is one which is hardly germane
to the question, and I do not know that it is one which the mem¬
bers of the Society here will care to discuss to-day. He says
‘ ‘ the obvious effect of that policy if it should be adopted by the
Society and approved by the Privy Council will be to enable the
Pharmaceutical Society to continue an unprofitable, and, there¬
fore, unfair competition in the business in which we are inte¬
rested.” I do not think that is quite germane to the question,
and I do not think we need discuss it. But Mr. Wootton goes on
to speak, “At the same time, you will, I hope, do us the justice to
believe that we would not move in the matter if we were not con¬
vinced that the policy announced is unjust and unjustifiable.”
Now I ask to whom will this policy be unjust or unjusti¬
fiable? I fail to see where there is any injustice. We
are merely saying that in the future, in our opinion, it is
desirable in the interest of the candidate, and in the interest of
the Society that a ten guinea fee shall be paid after a certain date.
That registration fee will be sufficient to cover the expenses of
registration for life. According to the Charter and the Act the fees
as determined by bye-law are to be paid to the Treasurer of the said
Society for the purposes of the said Society ; therefore, wre are
obviously within our right to ask for any reasonable fee, but from
the candidate’s point of view we consider that a ten guinea fee is
not more than is reasonable. If we look to other bodies, for
instance, the dental profession or the veterinary surgeons, and find
that their fees, exclusive of the expenses of their various curricula,
are about twenty guineas in each case, we think that ten guineas
is not an unreasonable sum to pay for our qualification and registra¬
tion for life. We also think in the interest of the chemist himself,
probably he will value more highly that for which he has paid a higher
fee, and he will no doubt obtain it back in some form afterwards.
We also think that if these bye-laws come into operation there
will be fewer failures. It has been said, I have not gone into the
matter myself, that the average sum that is paid for the qualifying
examination is about £8 or 8 guineas at the present time. We
hope that if these new bye-laws are passed we shall have com¬
paratively few failures. As regards the failures, if a man makes
up his mind to go on failing as some appear to do for a goodmany
years he will in the end get the advantage, because under the new
regulations he has to pay 3 guineas only as long as he chooses to
come up, and there is no second 5 guineas. Much has been said with
reference to the large amount we are going to make by this charge.
All I can say is this, that as far as I know there will be a
considerable loss to the Society by the change which we
contemplate in the first part of these bye-laws ; that is to say, so
far as the First examination is concerned, we shall no longer derive
a revenue from the failures in that examination. We have no
evidence before us that there will be any large increase in the
revenues of the Society. Some people think we are going to make
a big income out of it. I do not think we shall, but even if
we do, I think it will be for the benefit of the whole body.
I think it will be for the benefit of the members and the associates
of the Society as well as for registered persons that this Society
should not lack in the sinews of war. We do not know what
expense we may have to incur one of these days, either with regard
to proposed legislation or legal matters, and I say it is a good
thing that this Society should be fairly well off. I do not think
that you gentlemen believe that there has been any very extrava¬
gant expenditure, personal or otherwise. I take it that you
believe that the whole of the money that has up to the present
time been spent has been wisely spent, and I believe you will have
confidence in your future Council, even if they do derive a little
extra income from this, that if they do they will also spend it in
the interests of the general body. Having said that, I will now
move —
“ That the fourteen bye-laws, Nos. 11 to 14 of Section 10, beabrogated, and that
the new bye-laws, Nos. 11 to 23, now submitted to this meeting be con¬
firmed.”
The Vice-President : I beg formally to second that.
Mr. Mackenzie : I rise now to move my amendment.
The President : I think I had better at once tell you, Mr,
Mackenzie, that no amendments are possible at this meeting. I
think I ought to make that quite clear both to you and to Mr,
Wootton, who has given notice of motion. The powers of this
meeting are simply to say yea or nay to these bye-laws. The
legislative body in this matter is the Council. The Council has
made and approved these bye-laws at three meetings, in accord¬
ance with the Statute. It then, in accordance with the same
Statute, brings them to this special meeting to ask it to say
whether they shall go forward or not. They can be either adopted
or sent back to the Council for consideration. In that case you
have only to vote against the resolution which I have moved. I
shall be very glad, I need not say, to hear Mr. Mackenzie and Mr.
Wootton or any other gentlemen who are here to-day speak on this
matter, but I must lay it down once for all that it can only be a
question of yea or nay, shall they be confirmed ?
Mr. Mackenzie : I would say in the beginning of my remarks
that it is very refreshing to me to hear from you, sir, that there-
has been a desire on the part of the Council to take action to-
redeem our position and to get an amendment of our present Acts.
That is really the fundamental principle that is underlying the
feelings of a great number of the members of this Society. We
cannot all come to London, but you are aware, Mr. President, that
by various little associations there have been opinions expressed
long before these proposed bye-laws now submitted had ever been,
thought of or drafted. I for one will hail the time when we can
with confidence and in the proper order of things go forward to
that higher education, but at the same time I think it is impossible
for us to overlook this fact that it is altogether useless to talk
about putting more restrictions and exacting more fees until
this Society is put in possession of the means of granting
those members that are qualified that protection which,
was the very basis of the intention of the founders in
1843. Without this being done we are but building castles
in the air, we are driving away the very business that we
are deriving a livelihood from, and bringing about a great increase
of these companies that are quite legal and quite open for anyone
to enter and are being entered upon to the detriment of the well-
being of the members of the Society. I say, therefore, it is oi»
that ground, and with the best possible desires I have, that
the Society should have a good foundation before it begins to<
build glasshouses on the top of the present structure. It is very
nice to cultivate such an idea, but without that foundation, which
will add to the income, it becomes us as business men to look te
our present situation. I say, therefore, it is protection that wo
wish, and protection as members we must have ; whether there be
those on the Council who know it, I say there is necessity for it.
There may be those whose lot has been cast in pleasant places,
and who have not felt the grip that many of our friends in the
country know right well. It is easy for one in a high position
and occupying a high place on the Council, but it almost reminds
me of the princess who stated that she was surprised at the
stupidity of people living in a famine-stricken city, because
she said “ I would rather eat cold mutton and bread
than starve.” That was her idea of famine. It may
possibly be that in London the right idea of the situation
is not felt ; therefore, it may be that with the best intentions they
are proceeding with haste to go on with a good thing at the wrong
time. The Acts of Parliament and the bye-laws we have, it is
true, but it is the benefit which our Acts have not given us that
we need now. I recollect well that when our Acts were passed we
were told that grand things would come, that we should get pro¬
tection and other things ; but when we come into Court we find
we have nothing but an empty shell. W e did not dream that the
Society was going to be upset on its main point, and that compa¬
nies could be established all over the country. I should have liked
to have seen Mr. Justice Hawkins’ opinion carried to the House of
Lords. I should have been distinctly in favour of spending a large
sum to have exhausted that point rather than to have accepted it.
However, it is accepted, it is there, and we have to deal with it.
Mr. Carteighe : May I just remind you in order that the
meeting may not be misled that that could not have been carried
to the House of Lords, because the judges refused to allow an
appeal ; therefore it is not our fault. Saddle the right horse, if
you please.
Mr. Mackenzie : I can only say that we would have liked better
to get the House of Lords’ decision.
Mr. Carteighe : That is a matter of opinion ; but we were not
allowed to do so, in fact.
May 22, 1897]
PHARMACEUTICAL JOURNAL.
439
Mr. Mackenzie : It seems to me that our misfortunes have
arisen from improperly applied English phraseology. If the clauses
of our Act had been definitely drawn we should have possibly had
a better result. We want to get them properly drawn, and I
think the responsibilities of our business justify us in asking that.
I am inclined to think the Council will do well to turn their
whole attention to the securing of this end, along with those
other pleasant things which we have heard from our
President to-day ; and I would say that our motto should
be “ Union is strength.” I think we have been too long a
thing of threads and patches, too long Jews and Gentiles with its
newer and outer coat ; we have been a conglomeration of many
strange materials, which combined as a whole has been tried and
found wanting as far as its compatibility with many in the trade,
who are outside our ranks. I think we have now come to the day
when our Council should be informed that we want legislation
by all means, but legislation in the direction of unity. We should
take the College of Surgeons of England or Scotland as a basis,
and do as they do, and embrace a given period not with the dis¬
tinction that we have in the Pharmaceutical Society, but
making its membership one grand standard. We must aim at
one standard of membership before we can ever have that unity
that we need, and that I think we ought to have with regard to
the matter before us. I say boldly that it is in no carping
or fault-finding spirit that I would raise the slightest objection or
call to mind things that have apparently been forgotten in the
Council, so far as we outsiders know. I speak only of what we
have read and heard. I think we should be downright
earnest for our case, and downright earnest before stir¬
ring up the country and bringing up the necessity before
men who grumble at the condition of things and tell us what the
Council do in order to satisfy them that they are justified in going
forward for amended Acts, and that such amended Acts should
embrace at the time of passing every man of business. I hold,
further, that membership of this Society ought to be open for
every associate. It is an anomaly that there should be so many
kinds of degrees. We ought to come to that stage when we should
have a common fellowship. Who will say that the day for asso¬
ciates in business has long since gone by ?
A Member : I rise to a point of order. I submit the gentleman
is not speaking to the resolution before the meeting.
The President : After what has happened, Mr. Mackenzie is
having more latitude than is ordinary, but I do hope he will confine
himself to the question before the meeting.
Mr. Mackenzie : I am only bringing this forward by way of
illustration, because I hold that we ought to have a Bill that will
bring about the abolition of such an anomalous condition of things,
which is adverse to our best interests. If you will follow me, that
is the point I wish to make. I hold, further, that these bye-laws
will not give us what we want. We have discussed bye-laws here
before, but they have not been brought into law. The reason
given, so far as my memory goes, was that the subject of them
was more suitable to be dealt with by an Act of Parliament
than in a bye-law. I hold that we ought to strive to
improve our Act of Parliament, which at the present
time is a thing of threads and patches. I therefore ask
that we should have uniformity of membership, uniformity of
privileges, and at the same time bring all who are in the business
within our fold. Let associates who have passed the Minor be
admitted to membership right off, and let the examinations be
divided into a Major examination for principals and a Minor
examination for assistants. I will refer now to the hardships of
the present constitution, and state how I think the prosecutions
which have been instituted adversely affect the interests of the
Society. It is especially hard on the young men. We find young
men who have served their apprenticeship coming into the great
cities, such as Glasgow, and seeking for situations in doctors’
shops because they have more time for study. I main¬
tain that you should give these young men a helping
hand, as was said in the Journal the other day. With
regard to some of the prosecutions that have taken place in
Scotland of young men who have afterwards passed their examina¬
tions, they have had to go through the Sheriff s Court, and it will
always stick to them, they will be branded, and it will be said that
their own Society has had them up before the Courts, and it cannot
be to their interest or credit. I say in the interests of the young
men these prosecutions should not be proceeded with. A judge
said the other day he did not think anything of the fairness of
bringing a paltry prosecution for selling a pennyworth of opium
months after the sale took place.
The President : I think you are not quite speaking to the
point. I do not know whether you are arguing that these bye¬
laws should not pass in order that young men should not pass the
examinations after being unqualified assistants to doctors.
Mr. Mackenzie : I want to make the Minor examination a
qualification for assistants.
The President : That is not dealt with here at all.
Mr. Mackenzie : It bears directly on the present position of
things. You are not getting the young men into the Society as
you would do if you were more friendly to them. I hold that it
is a wrong time to come and ask for our consent to a set of bye¬
laws when we ought to be going to Parliament and asking for
an amended Act to deal with the question that is at the root of
our very vitality. It is all very well to say that assistants will get
better salaries.
A Member : Some of us who live in the country wish to get
home to-day. I should be very glad if you could confine your
remarks to the point.
Mr. Mackenzie : Instead of aiming to make a profit from our
examinations, I think we ought to begin with unity as our cry,
consolidate our foundations, and bring in all the members.
Mr. Wootton : I understand, sir, that your ruling applies to my
amendment.
The President : Yes.
Mr. W ootton : I will ask you to take a note that I respectfully
protest against your ruling. It dues not matter to me whether
I speak to your motion or in favour of my own.
The President : I merely repeat that I see that this meeting
has been convened ‘ ‘ For the purpose of considering, and if thought
proper, of confirming and approving new bye-laws to be submitted
to the meeting by the Council in accordance with the provisions of
the Charter.” I rule that it is only competent for this meeting
either to approve or disapprove of what is before them.
Mr. Wootton : I submit to your ruling, of course.
The President : As I said before, I am willing to hear you to
any length with regard to the point you wish to discuss.
Mr. Wootton : The point of your ruling is to give me no
opportunity to make my selection of the bye-laws ; pointing out
those that I approve of and what I disapprove of. I approve of
a part and disapprove of the other part. I disapprove of one bye¬
law (and only that one) which would increase the Minor examination
fee. To economise your time, sir, I will limit my remarks strictly
to that one. I have carefully read and studied all the arguments
which have been put forward on behalf of the propositions which
are now made. When you first proposed them to the Council
they were almost unanimously advocated on the ground, both
express and implied, that the examination at the present rate did
not pay. It was stated so in so many words, and it was also
indicated by a good many speakers then, and has been
indicated by a good many since, that the men coming into the
trade did not pay as they should do for the protection which the
Society was going to give them and for the expenses of administra¬
tion. That is the main point upon which I wish to speak. A great
many other arguments have been put forward, but I do not think
it is worth my while to occupy your time by alluding to them. A
large number of speakers and writers have indicated that the work
of the Pharmaceutical Society is of such assistance and of such a
beneficial character that it is right to impose this extra tax on the
men coming into the trade. I do not say that that has been for¬
mulated in so many words by anyone, but it has been the general
burden of a large number of the speakers. Of course, without
entering into the question of the premises at all, all I say
is that in that case the inference is not proved, and it
has not been proved, because, however beneficial the work
of the Society may be, it is certain you have no power
to compel people to pay for your beneficence. Then, to deal
exclusively with this question of whether the examinations
at the present rate pay, I wish to use the term in the broadest
possible sense, and if you can show by any means that the present
fees do not fully pay the Society, I perfectly agree that you have
an abundant right to ask for an increase ; but my point is that I
controvert the statement from the beginning. Without going into
any previous financial statement, it will be quite sufficient to take
the one for the year 1896. That happens, perhaps, to be rather
favourable to my argument, but it is a fact that any of
the financial statements from 1892 onwards, when the new
scale of fees came into operation, would answer my pur-
440
PHARMACEUTICAL JOURNAL.
[May 22, 1897
pose equally well, and . all my remarks will apply
to them just as much as to the year 1896, with the exception of
small details. The revenue in 1896 from the examinations
amounted to £9659. This includes a small' sum, less than £400,
received for the Major examination, and as the cost of that exam¬
ination is probably greater than the revenue from it, it only affects
jny argument as against myself. The total cost of those examinations
^as shown by the financial statement, amounted to £3492, leaving a
gross profit of £6167. But of course it is replied that that does
not meet anything like all the expenses incurred by the Society.
There are the clerical expenses, the rent for the place
where the examinations are held, and many other incidental
matters. It has also been pointed out, and very properly,
that all men coming into the trade may be fairly
expected to pay their proper proportion towards the adminis¬
tration of the Pharmacy Act, which is put into the hands
of the Pharmaceutical Society. With all that I heartily agree. It
has been difficult to get anything like a fair statement of what the
proportion should be to charge to the examination. Some of us
have considered that you might charge half the rent and half the
office expenses, and so on. I think that is a very handsome allow¬
ance. But, without quibbling at all about the amount, suppose
you charge the whole lot of the expenses — all the rent, all the taxes,
all the salaries, all the wages, all the repairs, the furniture, fittings,
the gas, the water, coal, the cleaning, the stationery, the printing
(not of the Journal), all the postage, all the Scotch law, and all
the expenses of maintaining the Register out of the profit you get
out of the examination — you can pay for all that, and then have
about £700, out of which you can nearlypayforyourmuseumandyour
library as well. Y ou pay therefore out of the examination not only for
the perfect administration of the Pharmacy Act as far as you
administer it, but also for a very large part of your own purely
■voluntary Society expenses. This is out of the present fees, and
yet the Council now puts forward a claim, and is to submit it to
the Privy Council, to nearly double the qualifying fee. That is
the case that I wish to put against your proposal. In one of the
discussions on this subject one of your supporters in the early
stage of the controversy made the remark that it was very easy to
prove anything by merely shuffling the figures. Well, after some
months of consideration, your side has shuffled the figures so as to
prove your case. The article in the official Journal which I read
last week entitled “The Dual Function of the Pharmaceutical
Society ” was really the strongest argument that could possibly be
brought in support of the amendment which I was asked to put,
but I was not allowed to. The writer set himself to prove that
the subscriptions of the members and societies fully paid for all
the Society’s expenses, and that the examination fee is not suffi¬
cient to pay for the public functions of the Pharmaceutical
Society, and he showed this by two accounts, one below
the other. His argument would have been very effective
if it had been made out. In the account of the Society’s
expenses he debits to the Society the Journal and the post¬
age thereof, the Society’s meetings, the library, and the calendar.
To the examiners he actually charges the whole of the establish¬
ment charges, all the rent and salaries, which I, for the purposes
of argument, just now assumed might be allowed, although I can¬
not admit that it is a reasonable allowance ; he charged also the
School of Pharmacy, the Research Laboratory, all the Scotch
and law expenses, all the annuities, and the Museum. I really
think it is hardly necessary to discuss this argument because it is
so palpably and obviously absurd. One would like to ask why, if
the School of Pharmacy is to be charged to the candidates — you
say you must charge the School of Pharmacy because it is a model
school — then I presume the Journal would stand on exactly the
same ground. It is published as a model Journal. Why should
the Laboratory be charged to the Society and the Museum
to the examiners ? One is as little public as the other,
no outsider has a right, I presume, to enter either of them!
Then the Society’s meetings are charged a small sum
which, I presume, is for the expense of providing coffee and cocoa,
but nothing is allowed for the roof, which provides those Societies
meetings, the rent is to be borne by outsiders who have no right to
come to them. Until I read that argument I hardly realised how
utterly, hopelessly weak your case is. I have really said all I
have to say on the matter, but I should like to just quote to you
what your predecessor in office said on the question of these fees
when they were 3 guineas, not 5 as they are now, for the Minor
examination. In the Report for the year 1869— that is the first
year when the examinations were made compulsory on everyone
entering the trade — it is stated —
“ Your Council lias great pleasure in congratulating the Society upon its social
and financial advancement, and the general approval by the trade and the public
with which the new state of things inaugurated by the Pharmacy Act has been
received. The financial statement shows a large increase of members,
whose subscriptions have considerably augmented the revenue of the Society.
Your Council notes with satisfaction that, during the past year the. sum of
£4066 10s. has been invested in the Government funds to the credit of the
General Account ; that a further sum of £1000 remained on deposit with the
bankers, still leaving a balance in December in the Treasurer’s hands of nearly
£1000.”
£6000 made clear profit out of the examinations in that one
year. Of course it was rather an exceptional year, but that,
profit went on year after year, though not to the same
amount. The Society became a little more lavish and
quite properly so. I do not want to see the Society save up
all its money. They spent more money, but still they kept on
saving. Many of us recollect how they went on with a constant-
saving of £2000 and £3000, and it seemed impossible for the
expenditure of the Society to overtake the income until Mr.
Carteighe came to the rescue. Mr. Carteighe was appointed
President in 1882, and we all remember that he held that office
until 1896. In 1882, the first year of his Presidency, the total
expenditure of the Society amounted to £14,300. In 1895, the
last year over which he had control, it amounted to £21,800,
or just 50 per cent, increase. I do not want to go into
it in detail, and I am sure I do not wish to allege that Mr.
Carteighe is responsible solely, because I think the whole Council
are responsible for voting for it, but that one item shows and
explains the reason why this demand is made, and I say that the
whole of that expense has been devoted, with a few trifling ex¬
ceptions, perhaps the law expenses have increased, b ut to- no
extent worth speaking about, nearly the whole of that £7000 increase
in the expenditure has been devoted to Society pur poses.
You will say, quite rightly I am sure, that the Pharmacy Act gives
you the power to devote such money to pharmaceutical purposes.
That is true, but that is no reason why you should extract any
amount of money that you like to ask for. All I can do now is to
appeal to the meeting to vote on this simple question ; is
it a fair thing to charge the Society expenses, as you are
aiming to do, to those least able to bear it who come into
the trade ? You are going to charge a very serious addition
to the expenses of the young man who enters the trade.
You have argued to-day, and you have argued before that you do
it in the interest of the young man, and if the meeting thinks so,
they will vote in favour of your motion I presume, but how yon
can allege it is to his interest to charge him ten guineas for the
same thing that you would have given him for five guineas I do-
not understand. Then a great many questions have been raised
during the controversy which have really no connection whatever
with the main question. For instance, there was an article
published stating what the cost of the Pharmaceutical J ournal wa3-
fifteen years ago,* and a member of the Pharmaceutical Council,
speaking to his constituents at Plymouth, said that was a complete
answer to all that has been said.
Mr. Park : I beg to contradict that statement. That meeting
was very improperly reported. You were represented at that time
by a youth of eighteen, and I should be very pleased if you would
publish the report that you had supplied you. It was a half
report that was put in your paper afterwards. I wrote a letter to
you explaining that, and you did not see fit to answer my letter ira
your paper.
Mr. Wootton : As that charge has been made against me, I
must take up another minute or two of your time to reply to it,
because when I heard Mr. Park’s statement the only question was,
he said the amount came to 4s. 4 d., and I sent a special represen¬
tative to him, who I believe called upon him and asked if that was
a correct statement, and he sent me up a statement of what he
gathered, of which I published every word.
Mr. Park : You are at perfect liberty to publish my own remarks
which I gave to your representative in writing. The gentleman who-
represents you I believe was, owing to holidays, unable to attend,
and the youth who did represent you did not evidently grasp
the question. I gave him a report of what I had said, which
appeared in the Pharmaceutical Journal, in which I made no reference
to the cost in 1895 and 1896. I think you will see in the report
that you published yourself I referred to the increased expenditure
of later years. I said in my letter to you that I referred to later
* From 1881 to the end of 1S95 the average cost of the Journal was 4s. 4tl. a year
for each subscriber (see ante, page 255). [Ed., Pharm. Journ.]
May 22, 18971
PH ARM A OF HTTP AT JOURNAL.
441
on, and you have actually reported in your paper that I did so
refer.
Mr. Wootton: There was another meeting at Liverpool, where
my friend Dr. Symes also raised the point. He said that these sort
of figures were all very well in their way, but he looked at the
matter from an entirely different point of view. He took up a
higher position altogether. He said this was a step in the right
direction, and that he had always advocated that any person enter¬
ing the trade should, ipso facto, become a member of the Pharma¬
ceutical Society. He would advocate, and I assume that those
who agree with him would equally support a Bill to take to Par¬
liament asking Parliament to compel every chemist and druggist,
as he becomes a chemist and druggist, to subscribe to the Pharma¬
ceutical Society, whether he wants or not.
The President : I do not think that point is before us, Mr.
Wootton.
Mr. Wootton : No, but I am asking that these matters which
are not before us, and which have been raised as, I
may say, red herrings, should not influence members of the
Society in their vote to-day. However, I will not raise any more
of them. All I will ask the members is to vote that they should
pay their own expenses themselves, even if they have to raise their
subscriptions from one guinea to two guineas. That is a new bye¬
law which I would support willingly. I would ask them to vote
and say that they will not any longer sponge upon those poor
fellows who are coming into the trade.
Mr. Robinson : I have listened with care and attention to the
remarks which have been made by Mr. Wootton, and I quite agree
that the whole policy of the Council in asking us to pass these bye¬
laws is raised here to-day. I say that it is the duty of the Council
to amend their bye-laws if they think it is necessary. They have
done so in the past, and whatever may be the vote to-day I have
no doubt they will have to do it in the future ; therefore I say they
are well within their right in asking this meeting to confirm the
new bye-laws. Before dealing with it in detail, may I say I am
surprised at the very minor key in which Mr. Wootton has intro¬
duced this matter ? I thought we were going to have a great fight
over it, but I do not see that he is in a fighting humour, and that he
has confined his remarks to the question before the meeting : What
is the object of the Society ? I do not know whether Mr. Wootton
will accept my assurance, but I can tell you this, that I see from
the published statements of the Council that they do it because
they think it is the proper thing to do in the interests of the trade.
I have made personal inquiry, and I am told that it is not with the
view of sponging upon the young men who are coming into the
trade, but that it is required for the purposes of the Society. It
is almost tempting to go into it in detail if the hour was not so
late, therefore I will endeavour to come to the question at once.
He bases his argument entirely on the fact that he thinks there is
no necessity for raising the fees for the Minor examination. He
argues in this way that the fees hitherto paid by the candidate
have been more than sufficient to cover the expenses. I join issue
with him there. I say that the Society has two means of revenue.
It is the subscriptions of its members, and the fees paid by the
candidates. I say that both of those sums together are properly
used for the purposes of the Society. But if Mr. Wootton wants
more proof of that, I say emphatically that the fees of the candi¬
dates were always intended to pay for the Society. The Charter
distinctly says the fees shall be applied to the general purposes of
the Society. That is also confirmed by the Pharmacy Act of
1868, Section 7, in which the very same words are used. It is
therefore quite clear that it was always intended that the fees
received from the candidates, the examinees, should be available
for the expenses of the Society. So far from it being the
fact that the fees from the examinees have been entrenched upon,
it is the other way about, and applied entirely to the benefit
of the members. The members of the Society have
paid voluntarily a sum equal to £5000 a year. The fees
from the candidates have never paid the entire expenses of the
Society. If, then, it had not been for the voluntary subscriptions
of the members there would have always been a deficit. It is a
fact, as Mr. Wootton knows, and I have not the least doubt that
he has discovered, whether from reading the articles in the Journal
or not, that he was on treacherous ground in saying that the
Society were improperly using the fees from the young men.
When he adds that in so many years an excess of £6000 from the
examinations has been added to the funds of the Society I
think it is time we should get to very close quarters
with Mr. Wootton. I will take up the paragraph in
this paper, and I will do my best now to disprove what he
says. Mr. Wootton says in the Chemist and Druggist for
May 15
“ ‘ Four-fifths of those who pass the Minor examination do nothing to support
the Pharmaceutical Society, which registers them for life and looks after their
interests. It is only fair, therefore, that the fee should be raised.’ This was the
first official utterance by the President of the Society. We replied that the
revenue from examination fees from 1869 to 1895 was £87,000 in excess of the
direct expenditure."
Notice the words “direct expenditure.” It seems to me that
Mr. Wootton may justify himself in that by only meaning
what was paid to the examiners, but that is not anything
like the entire charge to be defrayed from the examination fees. He
says that the excess over the direct expenditure is profit. What is
the inference to be drawn from such a statement as that ? It seems
to me that the word “direct” did mean that all of this was
profit that had gone into the coffers of the Society from the
examination fees ; but it is nothing of the kind. His next item
is that the yearly surplus has always paid for the greater
proportion of the expenses of the Society. My answer is that those
fees were always intended to do that. Suppose there were fewer
members who join the Society, and suppose the income was only
£2000 instead of £5000, the Society would still have to be carried
on, and there would be less revenue received from the voluntary
subscriptions than there is now. Therefore, I say that the fees
were always intended to pay the expenses of the Society. Then
he says investments to the extent of £25,000 have been made from
the surplus of the examination fees. I say that was not so ; it was
from other sources. Then he says the subscriptions of members of
the Society fall far short of the expenses incurred on their part.
That all depends on the view you take of it ; if you say that the
members of the Society are to pay the general expenses of the
Society, then, of course, I quite admit that subscriptions will not do
so ; but if you look at it reasonably there is no doubt that the exam¬
ination fees are primarily charged with the expenses of the Society,
and it is quite evident that the money has been properly expended.
I entirely disagree with Mr. Wootton. The truth is that the sub¬
scriptions of the members have exceeded what might be
properly charged to the private expenses of the Society, and
of course I admit that the Journal is an item which is only
supplied to members, therefore the Journal is properly charged to
the subscriptions of the members, and I am quite willing to throw
in some other items, although I believe the Society, being an
educational body, is an ample justification for its keeping a library,
museum, and school of pharmacy ; and on that ground I say that
the expenses of the Society are rightly charged against the general
fund of the Society. I must confess that some months ago I
did not grasp it fully myself. The revenue received from the
subscribing members is £5000 a year, and adding the debit
balance of the Journal, which the Society has a perfect right to
carry on as it thinks fit, as well as £1000 more for the
expenses of the evening meetings, the calendar, and the library
— adding all that together, I tell you that the surplus from
the subscriptions has been considerable. The subscriptions
from the members amply cover the deficit on the Journal
account, and the £1000 I have referred to. Therefore it is totally
incorrect to say that the money received from the subscribers has
always been far short of what it should have been. Mr. Wootton
says that no one has made an attempt to controvert his statements.
I must leave it for this meeting to judge what is the fair way of
looking at the affairs of this Society. If they take Mr. Wootton’s
view, that the members who join the Society are to bear all the
expenses, they will vote against these bye-laws, but when they
realise that these bye-laws are introduced for the best interests of
the Society, then there will be an overwhelming vote for their con¬
firmation. I should leave it there if there had not been so many
statements in the public press on the matter, and I for one do not
think they should be passed over. I saw this stated by Mr.
Wootton, or under his authority ; he said, “Who will believe that
if the Society’s Journal had not had a loss that anyone would have
wanted to increase the fees for the Minor candidates ? ” He said
it was owing to the fact of having to subsidise the Journal,
and I believe he uses some words about unfair competition.
He said, “Who would admit that anyone would increase the
fees ? ” I want to tell Mr. Wootton that I for one easily believe the
Council when they say that it is not on account of the Journal that
442
PHARMACEUTICAL JOURNAL.
[Mat 22, 1897
they want to increase the fees. I do not see myself, with all the
facts that we have in our possession, that the raising of the fee
will be a bad thing for the young men themselves. I desire to
refer to this in connection with that point. It is known that the
candidates at the present time pay more than five guineas on the
average ; they go up for the examination without being fully pre¬
pared, and the average fee paid by the candidates I am told is
somewhere about £8. If increasing the fee to ten guineas makes
the candidates take more care first of all before they enter the
business of a chemist and druggist that will be a good thing, and
if it makes them take more care that they are properly prepared
for examination before they come up, that would be, too, a good
thing for the credit of the Society. Mr, Wootton has asked several
questions, and I think it is fair that I, in my turn, should ask a
question of Mr. Wootton. It is this : “ Who will believe that Mr.
Wootton, a pharmaceutical chemist, when he sees the action
of the Society, doing something that is clearly shown to be
for the benefit of the Society — who would believe that if he were
not the Editor of the Chemist and Druggist that he would have
made such a remark as he has ? ” It is so clear that one need not
further go into this matter before this meeting. I travelled to-day
on a 2d. omnibus with a distinguished Councillor, and he said :
“You do not suppose that editors believe what they write ? ” I
am inclined to think that is the case. Though Mr. Wootton may
have thought there was some unfair competition with him, he
must see by this time that it is not so. I for one would not be a
party to anything of the kind. I have been a subscriber to the
Chemist and, Druggist as well as the Journal. I may be told by
the Editor and Proprietor of the Chemist and Druggist that it is
their business, but are they quite sure that in taking up this line
of hostility to the Society, and sowing dissension as they are
doing, that their own subscribers will approve of it? When
I find that they incite young men to write to the Privy
Council protesting against the confirmation of these bye-laws, I
think they are treading on very dangerous grounds, and I am
exceedingly sorry to see it. It does not matter much what people
say — all the members will know that words do not count for much,
but this I do say emphatically, that the J ournal expenses are not
primarily the cause of this proposed increase of fee. It is quite
true that some seven or eight years ago I said, “ Why do not you
make the Journal a better one ? ” I recognised the fact that we
had a Journal, and that it did go amongst our subscribers, and I
said, “ By all means let it be improved.” My suggestion was not
taken very kindly at that time, but since then I am glad to say it
has been improved, but I am not so foolish as to say that you
should not look into the financial matters connected with the
Journal. May I offer another bit of advice to the Council, or the
Committee, or the Editor (I do not know which it is), while you
have made the Journal a better journal than it was, cannot you go
a little further and see that you are getting the full value for the
money that you spend on it. My friend, Mr. Richard Reynolds,
writes me under date of yesterday referring to the Journal, and says
“ By comparison with its immediate predecessor he has remarked
a great advance, but the Press generally has been the subject of so
much enterprise during the last ten years that literary matter, illus¬
trations and get-up are immensely advanced on what used to be the
case, and he concludes by saying that he is certain the style of the
Journal is not creditable to the Society. I thought it would be of
interest to the Council to have such a valuable opinion as that of
Mr. Reynolds. I believe you could get better printing and a
better turn-out generally without increasing the expense, and that
if you continue your exertions as regards the Journal, you will
make it more successful and more a medium for advertisements.
I am sorry if I have taken up too much of your time, and I will
leave my friend Mr. Carteighe to deal with any other points which
do not concern me, and will only say that in my opinion the Council
is well justified in making the alteration in its bye-laws. I do not
believe for one moment that the acrimonious discussions which
have taken place will influence us in voting against the Council.
We sent them to do the best they could ; they come before us
deliberately and unanimously with their proposals, and I hope they
will be confirmed to day. I have very much pleasure in suggesting
to this meeting that we do so with the utmost heartiness and
thoroughness, and I believe it will be for the best interests of the
Society generally.
Mr. Glyn-Jones : I am sorry that for a moment I questioned
your ruling with regard to this meeting, but I want to be quite
clear on the point. This is a resolution that these bye-laws should
be voted for as they stand, and there is practically before the
meeting a negative to that, that they should be opposed, and nofe
confirmed as they stand. Now I do not want to support either of
those votes, and I will give you my reason for not doing it. Mr.
Wootton has told us that he was prepared to vote that certain,
bye-laws be confirmed, and that others be rejected, and to some
extent that is my position ; but I ask, Is there anything in our
bye-laws to prohibit this meeting deferring the confirmation of
them until certain things take place ? Can the confirmation be.
postponed ? Is there anything in our bye-laws which says that at.
this meeting these bye-laws must either be accepted or rejected ? I
ask this because if I am in order I should like to speak to this-
motion if this amendment which I have in my hand is out of
order. If your ruling holds good, then my amendment is cer¬
tainly out of order. It is this, that the confirmation of the bye¬
laws be postponed pending the report of a committee, such com¬
mittee to ascertain approximately the amount of income expended
in connection with the administration of the Pharmacy Act.
The President : I have ruled, Mr. Glyn-Jones, that there can
be no amendment whatever at this meeting. We are here for the
purpose of confirming certain bye-laws or not confirming them.
Mr. Glyn-Jones : I am sorry for that, because in anything I
have to say I should not like it to appear that I am desirous of
opposing the whole of the bye-laws. I am certainly at one with
this Council in their desire for insisting on a better preliminary-
education, but when it comes to the other part, we have had
figures put before us, and I admit that the opposition has come
from what is, on the face of it, a prejudiced source — there is no
question about it, and we must recognise it — but if an argument
is put forward there is no reason that we should not consider it
because it comes from a prejudiced source. There must be a cer¬
tain amount of truth in it. I am here speaking entirely as a private
member of the Society, and I suppose no body I am connected with
will object to my having a pharmaceutical conscience. Therefore I
say that I look with the greatest amount of eagerness for what
could be considered a full argument to certain arguments which
have been made by chemists and druggists against these bye-laws.
The argument has been that this Society has a dual capacity. On
looking at the current issue of the Journal I find it is admitted
that there is a dual function of the Pharmaceutical Society. Well,
gentlemen, it may be a matter of opinion that a man who becomes!
a chemist and druggist should pay for any advantages which this-
Society as a Society is able to confer, whether educationally or
in any other way, but what I am anxious about is that we should
avoid further restraining the vast number of chemists and drug¬
gists from joining this Society. It is admitted, and it is a
lamentable fact that out of the large number of chemists
and druggists, we have only a few adherents to this Society.
I am sorry to say that the application for an increased fee rather
brings home to me this idea, that the Society has come to the
conclusion that they can no longer look for voluntary support from
those who are still outside the Society. It appears to me that for
the private affairs of this Society we are not able to command the
support of the trade to such a large extent as to enable us to pay
for them. On looking through the current issue of the Journal I find
that there a division has been made. It seems to be somewhat
arbitrary. In going through the figures I find there is a balance
to the Journal account and other things, and there is an income
from the private sources of the Society of some £4000 odd. We
are told that the interest which is shown in this income has been
earned by the surplus from the examination fees. I am not in a.
position to say whether that is so or not ; but I do think that,
this meeting ought to be in a position to have the figures before us
so that we ourselves could come to a conclusion on this matter. I ami
puzzled yet to find out what the private concerns of this Society
are. Here there is an attempt to explain it, and we have the
library charged to one head and the museum to another,
I fail to see why that should be, because I think I am right in
stating that nobody who is not an adherent to the Society has any
right to enter either of those institutions. If they like to ask
for permission I have no doubt it will be given to them in the
same way that anyone asks to go to the museum of the Royal
College of Surgeons, but my point is, that no one but an adherent
has a right to the use of those institutions. The question comes-
to this : Are the Library, the Museum, the School, and the
Journal all things which are run in the interests of the general
trade ? I believe with slight modifications they are, but appa¬
rently there are a large majority of the trade who do not believe
that, and I am struck forcibly with an argument that has been
made by our leaders. They have said this : You can put the
Fat 22, 1897]
PHARMACEUTICAL JOURNAL.
443
advantages of the Society before the trade. You can bring a horse
to the water but you cannot make him drink. Apparently you
are going to make him pay for it whether he drinks it or not. It
would be like my asking one of you to lunch and saying “ Now we
will share the expenses of this lunch,” and I say “ Bring a fowl,”
and you say you do not want a fowl. I say “ It is the right thing
for you; I know better than you.” I say “We will have vege¬
tables.” You say you do not want vegetables, and when that
account comes to be settled, on looking down the items I say
* ‘Divide it between us, you pay for the vegetables, your friend
will pay for the wine ; he said he did not have any, but you
say he ought to have it, it is the right thing,” and I
say “I will pay for the bread and the gravy.” My
point is this : If you wish to secure the support of the rank
and file of the trade, you must show that the income you are ask¬
ing for is to be used in their interests. There are a large majority
at present who do not think so. I think they are wrong in not
seeing that the school and other expenditure is for the general
interest of the trade, but the question I ask you is, Is it right to
compel them to pay for it whether they see its advantages or
not? We have to go to the Privy Council to have these
bye-laws confirmed, and before the Privy Council grant that I
believe they would want to know a little more of the financial con¬
dition than you at present have been able to put before the
members. Our own Auditor has told us that it is a lamentable
fact that we have no balance sheet. It is a lamentable fact that
we do not know what the school costs us, and we do not know
what the Journal costs us. I am making the statement that the
financial statement is not a sufficient guide to us as to what these
things cost us, and our Auditor has practically told us the same
thing. My point is this ; if those particulars are to be given to
the Privy Council, why not to this meeting? Would it not be to
the advantage of the trade at large that we should say that no man
is compelled to pay ! In ether words, that our legal Secretary’s
work should be superseded practically by an income-tax collector.
That is what it comes to. That the men who will not voluntarily
subscribe to the Society are to be made to do so, to subscribe to
certain things which they foolishly do not think for their own
benefit. Of course, we have a perfect right to have these bye-laws,
but the question is, Is it politic, is it wise?
Mr. Barnard : It appears to me that the whole of the discus¬
sion has been on a wrong footing. It is all a question as between
the Journal and the Chemist and Drtiggist, and I am getting tired
of it. There is an old saying which appeals to me very forcibly:
“You can tell bigger lies with figures than with anything else.”
What I have to suggest to the Council is that a delay in passing
these bye-laws is desirable from altogether another reason. I do feel,
sir, that we ought, before we increase the difficulties and expense,
and so forth, of getting into the trade, the chemist and druggist, if
possible, to have something given in return for this extra expenditure
and increased difficulties to young men coming into the trade. But
will this increased expenditure give any consideration to it ? I am
afraid not, for the simple reason that the more you increase the
difficulty of entering a trade or profession, the more likely, and, as
a matter of fact, the more frequently, you have illegal opponents
in the business. At the present moment we have in the East-End
of London an enormous number of drug stcres springing up which
are just outside the pale of the Pharmaceutical Society. Could we
not before we alter the bye-laws and double the fees get back our
old principle, the principle that our first Charter recognised ? In
the very first Charter it stated that the Pharmaceutical Society
was for the education of chemists and druggists and for the pro¬
tection of trade interests. In the first Act of Parliament, passed
in 1852, the words are not as in the Act of 1868 ; that is who
shall assume the title of chemist and druggist shall be liable
to a penalty, but we all know what the words are : those who
shall assume, use, or exhibit any name, title, or sign implying that
he is registered, or that he is a member of the Society, that is the
wording of the first Act in 1852 — he shall be liable to a penalty.
Before we alter these bye-laws ought we not as a trade to have
considered the very great question whether we could not have
got an amended Act of Parliament whereby we could have dealt
with those who pretend to be chemists and druggists ? It was
necessary that members should belong to the Pharmaceutical
Society, so that they should be pharmaceutical chemists or dis¬
pensing chemists for the guidance of the public in 1852. If a
man put forth that he was a pharmaceutical chemist, then
Parliament recognised that in order that prescriptions might
be carefully and properly dispensed that he should be liable
to a penalty if they were not. But now almost forty-five
years have passed since Parliament has recognised that there
should be a method whereby all educated men should be distin¬
guished, yet there is no method now which renders it illegal for a
man to assume and pretend to be a chemist. I do ask this
meeting to-day to consider this very great question, whether they
should not negative this proposition on the part of the Council
with a view of taking the whole question into consideration with
regard to an amended Act of Parliament which shall give young
men entering into trade some privilege in return for the time and
money tnSy have to expend. I will not detain you, but I put that
view before the meeting, because it is a view which has not been
considered at all. It has been merely the question of trade inte¬
rest between the Pharmaceidical Journal and the Chemist and
Druggist as far as I ( a i see.
Mr. Wills : Mr. President and gentlemen, I should like to say
a few words on behalf of the students. I am very sorry that Mr.
Wootton’s amendment was not read, as I should have felt it my
duty to second it. As it is, we are only allowed to say a few
words. I have received a large number of letters from all over the
country asking me to oppose these bye-laws. I can tell you that
I have no objection, neither do I think anyone has, to the pro¬
vision as to an increase in the severity of the Preliminary. I think
that is quite right. It is only on the matter of the increase of the
fee from five to ten guineas that I object. I claim to know as
many assistants and chemists in business as any man living. L
have received a very large number of letters, but I will only tell1
you what some of them say. You have heard some of the objec¬
tions. One wrote to me and said he thought the Society were
worshipping, the Council especially, two gods, one was gold, not
their own gold, but the students’, and the other was their school.
Whether that is so or not of course I cannot say. There are
between 4000 and 5000 students at the present time who have been
introduced to the profession or the trade, who have passed the
Preliminary examination, and who yet have to present themselves •
for the final. They did so ; they entered the trade and passed the-
First examination on the understanding that they would be allowed
to present themselves for the final examination on paying the fee
of three or five guineas. Now they will have, after probably a
year or so, I do not know the exact time to be allowed, to pay five
uineas extra. I was speaking to a member of the Society on
aturday, and asked him what he thought of the bye-laws, and
of the Society. He said he had been connected with the Society
about thirty years, but now he had withdrawn his subscription
because it seemed to him that it was all fees, fees, fees. I know
these remarks of mine are very rambling, but I should like to-
mention this also, that all the members of the Society and some
of the officers even do not thoroughly understand what
these new bye-laws comprehend. I had a little conversation last'
week with one of your divisional secretaries, who said, “ What do
you think of the new bye-laws ?” I said, “ Some parts of them I
very much oppose, and I intend to do so because I think they are
very unfair on the poor students.” He said, “ Why, I think it is
the best thing that could possibly be for them.” I said, “ Why,
they charge an additional 5 guineas.” “Yes,” he said, “but do
you see what they are going to give them in return ? Now, as
things stand, you know, there is not one in so many scarcely who
would join the Society after they passed the examination, but now
they make them pay the additional 5 guineas that will include, of
course, their connection with the Society for life.” I said, “ Pardon
me, I think you are making a mistake. They are no more con¬
nected with the Pharmaceutical Society after they have passed and
paid their ten guineas than before.” He said, “ I can assure you
that is so. Instead of paying a guinea or half a guinea
they will have nothing to pay, but will be an associate
for life.” I told him if that was so I had been
labouring under a great mistake, but I would ascertain. I
made a reference to the Journal, selected one or two passages, and
sent it on to this gentleman, and he returned it to me thanking
me for it, and saying he had been labouring under a misapprehen¬
sion. There are others who really have the idea that by paying
the extra five guineas they are to be associated with the Society
for ever. With reference to students joining the Society, if you
inc re rse this fee from five to ten guineas, I think you will drive
them further away than they are now. The majority of them are
not very partial to the Society. I am very sorry to see it, but they
say “ No, having passed the examination the Society will not get
any more out of me.” If they say that now, and it is the general
opinion amongst the students, if you charge them the extra five
444
PHARMACEUTICAL JOURNAL.
[May 22, 1897.
guineas I do not think you will gain anything in the end. You
will only drive them further away.
Mr. Butt : They are outside now, they cannot go any further.
Mr. Wills : Some may support it on the ground that it will
keepM large number out of the profession, but I object to it on
that Aground. If you close the door against the legitimate
trader you simply open the door to the illegitimate trader. There
will be so-called chemists’ shops everywhere. 1 saw one the other
day, and had no idea it was not a proper chemist’s shop till I saw
a written notice inside to the effect that “poisons are not sold
here.” That will be everywhere the same. I think it is a mistake
to try and drive the young fellows out in that way by making the
fee too large. There has Been a profit of several thousand pounds
on the examination fees. Some gentleman says “No; take it
there is no profit.” Then if there is no profit I think it is in your
power to considerably reduce the expenses of conducting examina¬
tions. If you take one portion of it, say chemistry or botany, and
make it a written examination, one examiner would be able to
conduct the whole of the examination at one time and save the
Society a great deal of money. Personally, what I most
object to is this : the constant changes that are taking place.
The Council never seem to settle down to anything. No sooner do
they get one bye-law passed than they want to change it. The
Act of Parliament of 1868 allowed the candidates to present them¬
selves at any age. Then they soon passed a bye-law restricting
the age to 21, which was quite right. Then they altered the state
of the examinations and made them harder. Then finding it was
too hard -
The President : I am sure the speaker will understand that this
meeting is getting rather anxious for that meal to which Mr.
Glyn-Jones alluded, and I am sure he will curtail his remarks as
much as possible. We really do not wrant to discuss the course of
the examination, do we ?
Mr. Wills : We want to reduce the expenses of the Society as
much as possible. I am only giving the opinions I have received.
The President : I would rather have your own opinion than
that of these divisional secretaries and others.
Mr. Wills : My opinion is it is a most unjust demand to make
on these poor students, and I am very sorry they are not more
looked after. I personally am prevented taking a seat in the
Upper Chamber, but I may be allowed the position some day of a
seat in the Lower Chamber, and if so, I hope I shall represent them
properly.
Mr. Charles UmneY: I should like to say just one word, in
Drier to tell Mr. Wootton wdiy I am going to vote against him.
We have been talking all round the circle instead of going
to the pith of it. It is purely a question of ways and means,
and I do think that if we do not support the Council, in whom
I have every confidence in this matter, we shall make a very
great mistake. I do not support them from statements made
here to-day, I think many of them are quite beside the ques¬
tion, but the Society has an increasing expenditure that must
be met, and the better way is to meet it in the face. It
will go on increasing, and I see no other way whatever of making
money to pay the expenditure except to put up this examination
fee. It seems to me that is the true English of the mat¬
ter. You may talk round the circle as much as you like, but
that is the truth of the whole thing, and I myself shall vote
in support of the Council, because I believe they will spend
the money in a judicious manner, and for that reason only,
and not for the reasons that have been given on your side
to-day, will I vote against Mr. Wootton, and in support of
the Council. I have every confidence when the Council have the
funds in their hands they will spend them wisely. If they do not
get funds they will have bankruptcy staring them in the face in
the course of a year or two, because the Society’s expenditure will
go on increasing. You may shake your heads, but all societies’
■expenses go on increasing year by year, and you have to get
increased fees to meet that expenditure. For that reason I
support you, because I believe you wall spend the money in the
best possible manner.
Mr. Peter McEwan : I wish to call attention to Bye-Law
No. 11, and, as our solicitor is here, perhaps he will give us
his opinion. You will find that in that proposed amended
bye-law the first part of it is concerned with the First
examination, and the second part goes on and says, “After
June, 1900, persons desiring the said certificates of competence,
skill, and qualification under the Act of 1868 shall deliver to the
Registrar on behalf of the Board of Examiners a certificate,” etc.
What I want to ask is, What power have we under the Pharmacy
Acts to delegate this function to anybody ? If the First examina¬
tion, as is clearly recognised in the first part of this bye-law, is an
examination, then it must be conducted by certain persons
appointed by the Council and approved by the Privy Council, and
according to the 6th Section of the Act of 1868 you will find it
there stated, “ Provided that no person shall conduct any exam¬
ination for the purpose of this Act until his appointment has been
approved by the Privy Council.” How in the world can a board
of examiners — for instance, the Oxford or Cambridge local — come
under this definition, or any other similar body ? That is the point
on which I want information ; I do not argue it. Either the Pre¬
liminary is to cease to be an examination and to be made a
regulation, or it is not. That is point which might be made
clear. Are we to cease to make this First examination an exa¬
mination, or are we to continue it as an examination? If
so, the line upon which you are going seems to me to be
ultra vires. As to the money part of the question, I should
like to have spoken, as I expect very many here would like, but
like myself, you would not like to go into more figures at this
hour, and it is unnecessary to do so, as Mr. Umney has replied to
the criticisms passed on my colleague’s (Mr. Woobton’s) speech by
letting the cat out of the bag, so that really words would be
superfluous at this hour of the day. It is really because the
Society is in need of money the change is made, and one of our
Auditors says so.
Mr. Flux (the Solicitor) : That which has been called a First
examination has been only part of an examination. In the future,
as in the past, there will be but only one examination for any
status, and the examiners will examine in the particular subjects
which are reserved for them, and a part of their examination will
comprise their looking at the certificates which the examinee will
produce. They themselves will become satisfied by those certifi¬
cates that the applicant is competent in certain respects. The
examination will be one and entire.
Mr. Griffiths (Cirencester) : I will promise not to keep you
more than three minutes. My reason for wishing to say a few
words to you is to give my reason why I have come here to vote
against these proposed bye-laws this afternoon, but if I may be
allowed to make a side comment upon what has taken
place to-day, I should very much appreciate the indul¬
gence. I received a notice with my voting paper —
this agenda paper which was sent to me officially— but I think
it is a very great mistake to attend, and when we get here to be
told that that paper is ruled to be out of order by the Chairman.
It is rather like making a fool of us. I did come intending to
second the motion of Mr. James Mackenzie, and I find, although
this printed notice is sent to me officially, that it is, after all, out
of order. I should like to acquit the Council of any intention to
be discourteous to the members of the Society, but I think in future
if they would make some little provision against that sorb of thing
occurring again it would be a benefit. Now my reason for speaking
about the bye-laws is this — that I know a little about a class of
men in the trade whom I think veryseldom make themselves heard,
and about whom very little is known. I am a chemist
in a rural district, and I can only say, in the district
in which I live, one of the most rural in England, with¬
out any manufactories, but entirely agricultural, with small
chemists there, are entirely against these amended bye-laws,
and I think it is a great pity that anything should be done
in the present day which would widen the breach between the
outside trade and the members of the Society. My principal
reason for voting against this increased fee is not so much on the
principle of increasing the fee itself, but I think you are beginning
at the wrong end. You must remember that the Pharmaceutical
Act was passed nearly thirty years ago, since which time the con¬
ditions under which pharmacy is carried on have utterly changed,
and that Act has itself become useless for the purpose for which it
was intended. For my own part I think the best thing the Council
could do would be to elect a Parliamentary Committee to consider
the whole question of pharmacy law, and see if they could not
bring forward an amended Act which would be acceptable to the
great body at large. I think then they would have the support of
the trade, and we shall ultimately be a really representative
Society.
The President : I do not think it is necessary for me to prolong
this discussion. There have been a great many statements made
and opinions given, but they have been principally on the financial
aspect, and, as one of the speakers said, you can prove almost
May 22, 1897]
PHARMACEUTICAL JOURNAL.
4 45
anything from figures. I do not propose to enter into that matter
at all. I repeat what I said before, that wTe in our wisdom or in
our want of wisdom think that it will be for the benefit of the
whole trade or profession — -call it what you will — that we should
have this alteration, for it is one alteration. We say we think
that it will be better for our descendants at all events ; that we
shall have a better educated class of men coming into the trade ;
and that those men should pay five guineas more to start with ;
and that they will value their position all the more for having paid
that additional five guineas for it. I think I understood Mr.
Glyn- Jones to say that there is a tendency for men to come
less and less into the Society, and so we want more money.
I argue on exactly opposite lines. I believe if these
bye-laws are passed and approved by the Privy Council, we shall
have a larger proportion of men join the Society. We shall have
a better educated lot of men coming into the trade, who will
appreciate the good that is being done by the Society, and there¬
fore I think we shall be all the richer in that respect. This is the
first time I have been in this chair, but really, judging from some
of the remarks made, I should almost have thought the gentlemen
here were not members of the Society, but that they were taking
up the line of outsiders altogether, as if they wished this to be a
poor body, and wished us not to have money. I do not see that
there is any injustice in this proposal. Mr. Wills talked about
students, and so on. We tell the students, the candidates of the
future, that they must consider that one of the conditions of enter¬
ing the business will be that they must show evidence of a good
sound general education, and that they must pay ten guineas
for the qualification. I do not see the injustice of it. I
say once more, if we make any more money, and I
do not know who is going to prove that we are going to make a lot
of money, but if we "do I can answer for it that as long as I am on
the Council I shall do all I can — and I am sure every Council in
future wfill do the same — to spend any money we have in the
general advancement of pharmacy.
The resolution was then put to the meeting and carried by an
overwhelming majority, amid loud applause, there being about
six dissentients.
Mr. Carteighe moved a vote of thanks to the President, which
was carried by acclamation, and the President having thanked the
members for their courtesy and attention, the proceedings ter¬
minated.
ADJOURNED GENERAL MEETING,
Thursday, May 20.
MR. WALTER HILLS, PRESIDENT, IN THE CHAIR.
The adjourned meeting for receiving the report of the Scrutineers
was held on Thursday, May 20.
The Chairman of the Scrutineers, Mr. E. N. Butt, read the
following report : —
Scrutineers’ Report.
Martindale . 1790
Allest . . •. . 1779
Hampson . 1723
Atkins . 1700
Bottle .. .. 1693
Corder . . 1651
Southall . 1611'
Park . 1587
Grose . 1524
Leo. Atkinson.
John Holding.
C. A. Hill.
Thomas Tickle.
B. Thomas.
A. J. B. Cooper.
AV. Prior Robinson.
A. J. Brown.
Henry Wiggins.
John C. Umney.
Young . 1519
Warren . 1508
Harrison.. .. „ 1459
Carteighe . 1443
Sai ory . 1311
Campkin . 1144
Hyslop . 1112
Edward N. Butt, Chairman,.
J. Butterwortii.
G. W. Worfolk.
A. E. Tanner.
R. Fisher Young.
D. R. Jacks.
T. H. Powell.
Henry C. Birch.
Herbert Cracknell.
W. Arkinstai.l.
Ernest J. Eastes.
The New Council.
The President, as Chairman of the meeting, then declared that
the following gentlemen would constitute the Council for the
ensuing year : —
Allen, Charles Bowen, 20, High Road, Kilburn, N.W.
Atkins, Samuel Ralph, Market Place, Salisbury.
Bateson, Thomas, 23, Stricklandgate, Kendal.
Bottle, Alexander, 37, Town wall Street, Dover.
Carteighe, Michael, ISO, New Bond Street, W.
Corder, Octavius, 31, London Street, Norwich.
Cross, William Gowen, Mardol, Shrewsbury.
Grose, Nicholas Male, 8, Temple Street, Swansea.
Hampson, Robert, Norland House, Sevenoaks.
Harrison, John, 33, Bridge Street, Sunderland.
Hills, Walter, 226, Oxford Street, London, W.
Johnston, John, 45, Union Street, Aberdeen.
Martindale, William, 10, New Cavendish Street, W.
Newsholme, G. T. Wilkinson, 27, High Street, Sheffield.
Park, Charles James, 1, Mutley Plain, Plymouth.
Savory, Arthur Ledsam, 143, New Bond Street, W.
Southall, Alfred, 17, Bull Street, Birmingham.
Storrar, David, 228, High Street, Kirkcaldy.
Symes, Charles, 14, Hardman Street, Liverpool.
Warren, William, 24, Bussell Street, Covent Garden, W.C.
Young, John Rymer, 42, Sankey Street, Warrington.
After the report of the Scrutineers had been received, the
President moved, Mr. Martindale seconded, and Mr. Bottle
supported a vote of thanks to the Scrutineers for their labours.
This was suitably replied to by Mr. E. N. Butt on behalf of the
Scrutineers.
A vote of thanks was also accorded to the President for pre¬
siding at the meeting.
o o
We, the undersigned Scrutineers, appointed at the Fifty-sixth
Annual General Meeting of the Pharmaceutical Society of Great
Britain, do hereby certify that we have examined the voting papers
committed to us, and report the following : —
Voting papers reported by the Secretary to have been issued . . 3767
Voting papers received .. ... . . 2035
Voting papers issued, but not returned . . ... .. 1732
Voting papers received .. . . „ . 2035
Voting papers disallowed
Informal . . . • . . . 19
Received by post too late . . . . 75
— 94
Voting papers registered 1941
Vaccination to Counteract the Poisonous Effects of Ricin. —
The poisonous effects of ricin contained in the marc of Ricinus.
communis is well known. Cornevin finds that by heating ricin to
100° for two hours it is converted into a body which, injected
hypodermically, serves as an antitoxin to the poison. The
susceptibility of various species of domestic animals to ricin
is very unequal. Ruminants are much more easily affected by it
than pigs or fowls. Animals vaccinated with modified ricin were
tested eight or ten dhys after the operation, and were able to take,
with perfect immunity, a larger quantity of marc or seeds of Ricinvs
than would have proved fatal to unvaccinated animals. To two
small pigs of the same litter, one vaccinated and the other not,
equal quantities of castor oil presscake were given, adjusted to their
respective body-weight ; the unvaccinated animal died in twenty-
four hours ; the other showed no signs even of discomfort. Other
vaccinated animals have been fed for two or three months without
interruption with daily doses of castor oil seeds four or five times
greater than the lethal amount for uninoculated animals. — Comptcs
rendus, cxx., 835.
446
PHARMACEUTICAL JOURNAL.
[May 22, 1897
THE G. F. SCHACHT MEMORIAL.
After the proceedings of the Pharmaceutical Society were
concluded on Wednesday, a gathering of the subscribers to the
Schacht Memorial took place in the Examination Hall at
Bloomsbury Square, for the purpose of formally handing over
the portrait of the late G. F. Schacht to the custody of the Society.
Mr. Carteighe opened the proceedings by reporting that the
Committee had been successful in obtaining a replica of the very
excellent portrait in the possession of Dr. Frank Schacht. As one
of the Hon. Secretaries he had received one or two letters of regret
from gentlemen who were unable to be present, and one from Mr.
Martin he should like to read : — -
Newcastle-on-Tyne, May 16, 1897.
My dear Carteighe, — I am in receipt of your circular re the presentation of the
portrait of Mr. Schacht to the Pharmaceutical Society on Wednesday next, and
am extremely sorry that I cannot leave home to he present with you on the
occasion. Schacht was one of my heroes of pharmacy, and whatsoever I may
have said or done in connection with pharmacy, which retains my own self-
respect, is entirely due to the ideals which were created in my mind by Schacht
and others of his kind who preceded me in the work. I shall be glad if you will
mention how much I regret not being with you in person, as I certainly shall be
in spirit, when the portrait of our dear old friend is handed over to take its place
with Deane, Hanbury, and the rest.
With kind regards, Yours sincerely, N. H. Martin.
Mr. Townsend, late M.P. for one of the Divisions of Bristol, also
wrote to say he was sorry he could not come up to town that
week, or he should have been at the meeting for the presentation
.to the Society of the portrait of his late friend.
Mr. A. L. Savory said it was now some time since, at a
meeting of the Council which took place shortly after the death of
Mr. Schacht — an event which was deeply regretted by all who had
come in contact with him during his long and honourable
pharmaceutical career — a question was asked whether there was
any portrait of Mr. Schacht in existence. He was fortunately
able to say that he knew there was such a portrait in
the house of Dr. Frank Schacht, which was considered
by all who had seen it to be not only an excellent work
of art, but also a very capital likeness, and he further
stated his belief that Dr. F. Schacht would willingly consent
to a replica being made. Thereupon he was asked to approach Dr.
Schacht on the subject, and as he anticipated not only was the
consent cordially given, but every facility was afforded to the
artist for making the replica. The picture was by an artist who
had had the advantage from her earliest years of knowing Mr.
Schacht intimately, and on that account was more likely to be
. successful than if it had been painted by an artist who only saw
his subject for the first time. There was no difficulty in getting
.together the necessary funds up to a certain point, but there was
still a little more wanted, what had been received hitherto
having come entirely from Mr. Schacht’s old friends and colleagues.
He was in hopes until a few days ago that Mr. Giles, one of Mr.
Schacht’s oldest friends, would have been there to make the
presentation, but he was sorry to say that he was informed
in a letter, which he had mislaid, that Mr. Giles was
unable to be present, in consequence of ill-health. The task had
therefoie devolved upon himself, it being thought for many reasons
that he should take Mr. Giles’ place, and though he did not feel
that he could possibly do such justice to the occasion as Mr. Giles,
he yielded to no one in his desire to do honour to the name Mr.
Schacht had left behind him, both as a man and a pharmacist. It
was, perhaps, not inappropriate that he should take a leading
part on that occasion, seeing that he had the good fortune of know¬
ing Mr. Schacht intimately for a great many years, and that their
late friend’s early career as a pharmacist was passed in the firm in
New Bond Street of which he (Mr. Savory) was now a member. Mr.
Schacht started as a pupil under his grandfather, being apprenticed in
about 1836 or 1837 for seven years, and he was pleased to say
that the years so spent laid the foundation of a friendship
between Mr. Schacht’s family and his own which he was proud to
acknowledge and hoped would last for many years to come. If
Mr. Giles had been present he would have been able to give some
interesting reminiscences of Mr. Schacht’s earlier career.
It was marked from beginning to end by extreme ability,
by the most intense interest in his calling, by an earnest¬
ness in everything he undertook which was quite uncommon, and
by an absolute devotion to the Society of which he was a member
from its earliest days. He was one of the first to pass the examina¬
tion, and his diploma as a pharmaceutical chemist was No. 2. Fora
number of years he was a member of the Council. He was also a
Vice-President, and most ably filled the office. If they looked
back on the history of pharmacy they would see how much it
owed to Mr. Schacht in educational and other respects. He
might refer with pride to the intimate friendship with Mr. Schacht
which he enjoyed. It commenced when he entered the trade as
an apprentice at Bath. When he frequently met Mr. Schacht at
Clifton, he enjoyed his hospitality and received from him
many acts of kindness. In that Society they had had many
excellent Presidents and Vice-Presidents, and wherever possible
they tried to perpetuate their names and honour themselves by
placing their portraits on the walls, and he thought he was only
expressing the feelings of everyone present in saying that if they
had not taken this opportunity of having this replica made and
added to the collection, they would have been distinctly wanting
in not having the portrait of a man who left a name behind
him, which would always be respected and revered. On behalf of
the subscribers he asked the President to accept the portrait and
give it a place on the walls of the Society’s house.
The President said it was not altogether a pleasure to receive
this gift, the loss they had all sustained being still recent ; but as
Mr. Schacht had been taken away, it was a very great satisfaction
to him and to all the members of the Council to have this admir¬
able portrait, which he could assure the subscribers would be
taken the greatest care of and highly treasured. He had had
recent opportunities of speaking of Mr. Schacht, and after Mr.
Savory’s remarks it was not necessary to say much, but he should
like once more to record his opinion of him. Mr. Martin had
spoken of him as a hero of pharmacy, and he (the President) had
said that in his mind he wa.s the ideal pharmacist. There was
something about him very attractive ; they all knew that he was
very capable in his own particular line ; they also knew that he
was a man of the very highest principle, who would never take any
step or give any vote which he did not think was the absolutely
right one, but there was one other point which had not
been alluded to. There was a certain boyishness about
him up to the last which one could not help liking and
loving. It was impossible to know Mr. Schacht and be with him
without being attracted by him in the most marked degree. The
thanks of the Society were due to the subscribers for providing
this excellent portrait, and especially to the energetic hon. secre¬
taries, Mr. Savory and Mr. Carteighe, who had carried out the
project so successfully and quickly. They had also to thank Dr.
Frank Schacht for his co-operation, and in conclusion he should like
to congratulate Mrs. Tabor, the artist, on a very excellent portrait.
In the Council room were placed the portraits of a number of
distinguished pharmacists — men who had been an honour to their
calling — and he was quite sure they would always feel that this
picture was rightly placed near those of men like Bell and Allen.
He trusted it would remain there many years, and certainly every
possible care would be taken of it.
May 22, 1897]
PHARMACEUTICAL JOURNAL.
447
Pharmaceutical Journal.
ESTABLISHED 1841.
Circulating in the United Kingdom, France, Germany,
Austria, Italy, Russia, Switzerland, Canada, the
United States, South America, India,
Australasia, South Africa, etc.
Editorial Office : 17, BLOOMSBURY SQUARE, W.C.
Publishing ai\d Advertising Office : 5, SERLE STREET, W.C.
LONDON: SATURDAY, MAY 22, 1897.
THE SOCIETY’S ANNIVERSARY.
The result of the meetings held last Wednesday furnished
a most emphatic demonstration that the action of the
Council in regard to amendments of the bye-laws meets
with very general approval from the constituency by which
the statutory powers of the Society have been entrusted to
the Council as its Executive body. That result is in ac¬
cordance with the indications already given, by the resolu¬
tions passed at local meetings, of a great preponderance
of opinion that the amendments proposed are necessary
at the present time, and calculated to promote the in¬
terests of the craft. Such opposition as there was
to the confirmation of the bye-laws could not be
regarded as appropriate or well founded. The motion
of which Mr. Mackenzie had given notice could only lead to
an academic discussion, having no practical bearing on
the matter, and it appeared to have been framed without
regard to the fact that the Council, w7hich is for the time
being the Society, has decided that alteration of the bye¬
laws is called for at the present time. The only way in
which that proceeding could be counteracted would be in
the event of the Council having exceeded the powers dele¬
gated to it, or having exercised them in a manner that met
with disapproval, and in that case voting against the confirma¬
tion of the proposed bye-laws would have been the con¬
stitutional remedy. Naturally, therefore, Mr. Mackenzie’s
motion was ruled out of order by the President.
The motion of which notice was given for the Special
Oeneral Meeting by Mr. Wootton, was also ruled by the
President to be out of order, and the assumption upon
which it was based was so erroneous that it could not have
been supported had it been put to the meeting. Briefly
■that assumption was that the Society incurs a loss by the
publication of its Journal, and that the only reason for
increasing the examination fee is to provide a subsidy by
which the loss upon the Journal could be recouped. At
the meeting, and on previous occasions, it has been
.shown that this assumption is utterly unfounded.
There is no loss upon the Society’s Journal. The
■adverse balance which represents the cost of the Journal is
certainly less than half the amount received from
subscribers, and the remainder of that amount has been
.applied to the general purposes of the Society. With these
facts established it would have been wasting the time of the
meeting to enter into discussion of objections founded upon
such fallacious grounds. But on broader grounds several of
the speakers recognised the absurdity of making any real or
fancied rivalry with the Society’s Journal an argument
against the amendment of the bye-laws which the Council
had decided to be requisite. The insufficiency of the revenue
arising from examination fees for meeting the expenses
entailed upon the Society in the administration of the Phar¬
macy Acts, even when supplemented to a large extent by the
subscription income, is the main fact to be considered.
That is manifestly the reason by which the increase of
the examination fee is to be justified, without any reference to
what the subscribers may choose to pay for their own J ournal.
Upon that view of the matter Mr. Umney pointedly
expressed his intention of supporting the motion to confirm
the bye-laws, inasmuch as he regarded it as a question of
ways and means that must be dealt with directly in order
that the Society may be enabled to carry out with efficiency
the statutory duties imposed upon it.
In referring to the various details of the Council Report,
the President spoke of the educational work, which is one
of the most important purposes of the Society, as having
engaged much attention from the Council during the past
year. Besides the reorganisation of the School, the proposed
alterations in regard to the Preliminary examination and the
prosecution of research, the application to Parliament
for power to admit chemists and druggists to member¬
ship of the Society has also been considered, and in further¬
ance of previous efforts the Council is quite prepared
to take steps for promoting a consolidation of the
trade and the Society in that way. The mention of this
latter subject drew from Mr. Hambrook, one of the founders
of the Society, an expression of hearty sympathy and
approval, and many throughout the country will join him in
hoping that a very considerable broadening of the founda¬
tions of the Society will result from making the present
legal qualification the basis of membership of the Society.
THE COUNCIL ELECTION.
The result of the election for seats on the Council of the
Pharmaceutical Society is that all the retiring members who
offered themselves for re-election are returned once more,
with Mr. William Warren as their colleague in place of
Mr. Gostling, of Diss, a London’ member thus replacing a
country one. The figures do not indicate that any extra
enthusiasm has been aroused on the present occasion, though
the highest and lowest numbers of votes recorded for candi¬
dates are both in excess of what were recorded last year.
The voting papers received, however, numbered only 2035,
as against 2173 on the previous occasion, and it cannot be
regarded as satisfactory that 1732 voting papers were not
returned, or nearly 150 more than in 1896. The result
clearly shows that the loyalty exhibited by the members and
associates in business towards their elected representatives,
which has been petulantly declaimed against of late as though
it were a fault, shows no sign of diminution, the policy of
the retiring Council being fully approved of. The alteration
in the position on the list of some of the successful candi¬
dates seems to indicate that adverse influences have been at
work in respect of their candidature, but as it happens the
actual position of affairs remains as it was.
448
PHARMACEUTICAL JOURNAL.
[May 22, 1897
ANNOTATIONS,
The Annual Meeting oe the Society was a full and enthusi¬
astic one. Again the policy of the body corporate as interpreted
by the Council was loyally supported, and further proof was
afforded of the great confidence reposed by the electorate in the
governing body. The business of the meeting was got through
rapidly and without a hitch, such antagonistic speeches as were
delivered being more in the nature of criticisms of minor points of
detail than matters of principle. As showing the practical
unanimity of the meeting it is worthy of note that only one hand
was uplifted in opposition to the motion in favour of adopting the
annual report and financial statement.
The Special General Meeting followed directly upon the
adjournment of the Annual Meeting, the sole business then before
the members being the question of confirming or rejecting the pro¬
posed new bye-laws. At the outset, the President cleared the air
by announcing that no amendments could be considered, the only
course open to the meeting being to say aye or nay to the
proposed bye-laws as a whole. A somewhat desultory discus¬
sion then took place, in the course of which more than one of the
speakers was unfortunately interrupted by members who were
perhaps naturally impatient at being kept so long after midday
without food. At last, however, the end came in sight, and amid
repeated cries of “Vote! Vote!” the Chairman put the question
that the proposed bye-laws be confirmed and approved. The result
left not the slightest doubt as to the opinion entertained by the
members as to the desirability of the Council’s proposals, for out
of the whole of the large number present, only six voted in the
negative. And so the draft bye-laws passed th e last obstacle but
one, as all that is now required to legalise them is the approval of
the Privy Council.
The Schacht Memorial Painting was formally presented to
the President, as representing the Pharmaceutical Society, at an
informal gathering in the Examination Hall shortly after the busi¬
ness of the day was concluded. The first speaker was Mr. Michael
Carteighe, who read a letter in which Mr. N. H. Martin feel¬
ingly referred to the late G. E. Schacht’s great merits as
a man and a pharmacist, and spoke of the considerable in¬
fluence the deceased “hero of pharmacy” had exercised upon
his own career. Mr. Arthur Savory followed and, after
a brief account of the circumstances under which the idea of the
memorial originated and the steps since taken to carry that idea
into effect, he asked Mr. Walter Hills to accept the portrait on
behalf of the Society. On being unveiled, the picture excited
general admiration, and the prevailing opinion expressed was that
it is an excellent likeness. The interesting ceremony was con¬
cluded by Mr. Hills expressing the satisfaction with which he
accepted the trust and received for the Society the speaking like¬
ness of one who had been “ the ideal pharmacist.”
The Festival Dinner on Tuesday night was a great success,
and the event clearly showed that chemists are quite capable of
rising to the occasion in matters that arouse their sympathy. It
was a thoroughly representative gathering, but few of the familiar
names in pharmacy being missing from the list of guests, and
everyone present seemed to derive a maximum of enjoyment from
his surroundings. The dinner fully accorded with the reputation
the Hotel Cecil has already gained, the musical entertainment was
excellent, and the speeches were brief and to the point. Probably
no more pleasant reunion of British pharmacists and their friends
has ever taken place, and the general satisfaction manifested
should be regarded by those responsible for the arrangements as a
distinct compliment, fully compensating them for the arduous
labours spread over the past few weeks.
The Benevolent Fund List of donations and special subscrip¬
tions, published in this week’s Journal, is an extremely gratifying
one, the total amount received or promised being considerably
over two thousand pounds, or practically twice as much as was
recorded on the similar occasion ten years ago. Already then it
is a record list, but it is hoped that a still higher total may be
attained, and to that end it is proposed to keep the list open until
the end of this month. It ought to be possible to realise at least
two thousand five hundred pounds, and those individuals and firms
who have not yet notified their intention of contributing will
doubtless be glad of the extra opportunity afforded for assisting in
bringing about that result.
The Nature and Work oe the Benevolent Fund are perhaps
not so well known amongst chemists and druggists as they ought
to be, and the present opportunity is therefore taken of empha¬
sising the fact that all genuine cases of necessity amongst chemists
and druggists, and the widows of chemists and druggists, are aided
by temporary assistance when presented to the Council of the
Pharmaceutical Society. Chronic cases of distress may be per¬
manently relieired by the aid of annuities. As shown in the
Society’s Calendar, the system of granting annuities was com¬
menced in 1865, two of £30 each being then given. The amount
was increased to £35 in 1878, and in 1891 the Council raised the
amount to £50 per annum. A smaller amount is granted to an¬
nuitants under sixty-five years of age, according to the regula¬
tions. At the present time no less than forty-five annuitants
are in the enjoyment of a moderate fixed income from the Fund.
The relief granted during the year 1896 was as follows : —
Total casual grants . . . . £ 553 O 0
Total paid in annuities . 2232 10 O
Total relief granted during 1S96 . £ 2785 10 O
This amount was barely covered by the income from subscriptions,
interest on invested capital, and ground rents, whilst the whole
cost of administering the Fund was borne by the Pharmaceutical
Society, the Fund itself being freed from that burden.
Chemists and Druggists who are not connected with the Society
do not contribute towards these administrative expenses and,
unfortunately, they do not appear to feel it incumbent upon them,
except in isolated instances, to subscribe towards the Fund itself.
This is not as it should be when it is considered that the benefits
of the Fund are open to all registered chemists without restriction,
and that those who are assisted in case of need are, more often
than not, to be numbered amongst non-supporters of the Pharma¬
ceutical Society. Such being the case, it is only reasonable to
expect every member of the craft to contribute something
towards the Fund, if it is only half-a-crown annually. Even so
small a subscription as this brings a direct privilege, for
all contributors to the Fund of half-a-crown and upwards have
votes in the election of annuitants. With regard to the applica¬
tion of the money contributed, as matters stand the annual
subscriptions require to be drawn upon largely to pay the
annuities, though it is eminently desirable that the invested
capital should be increased sufficiently to insure from its interest
enough to provide means for those grants, as when once given
they cannot be recalled. It is important, therefore, that it should
be generally known that the interest of the invested capital is not
May 22, 1897]
PITA'S MACET7TTCA L JOURNAL.
449
half sufficient to pay the present annuities, amounting, as shown
above, to £2232 10s. As a result the proportion of the annual sub¬
scriptions absorbed in the payment of annuities leaves much too
small a balance from which to grant sums in casual cases, and con¬
sequently the Council is often unable to deal so satisfactorily
with many applications as might otherwise be the case.
The Present Subscribers Number Six Thousand approxi¬
mately, or about as many as subscribe to the Pharmaceutical
Society. But there are some fifteen thousand registered chemists,
of whom probably half are in business on their own account, and
it is not difficult to arrive at the rough result that nearly four
thousand chemists in business, if not more than that, do not con¬
tribute the smallest sum to the Benevolent Fund. If those four
thousand would only subscribe half-a-crown each, the result
would be to more than double the amount at present received
from subscriptions. All cases of distress could then be
much more generously dealt with than is now possible, the
number of annuities could be increased, and the invested
capital might also be increased gradually until the interest derived
from it should more than suffice to pay those annuities without
drawing upon the annual subscriptions. Chemists who are not
yet subscribers, therefore, are urged to do something, if it be ever
so little, in aid of the only insurance fund of the craft. Moreover,
former subscribers are urged to renew, and if possible increase,
their subscriptions, whilst everyone who sympathises with the
unfortunate and distressed is asked to assist by word and deed in
establishing the Benevolent Fund upon a sure and certain financial
foundation.
The Pharmacy Board or Victoria reports that only ninety-
three persons presented themselves for the Preliminary examina¬
tion in 1896, as against one hundred and fprty-eight in the
previous year, whilst twenty-five candidates presented themselves
for the Final Qualifying examination, and six for the Modified.
With regard to a request made by the Board of Public Health that
provision should be made by the Pharmacy Board for carrying ou
a system of examination for persons desirous of qualifying for the
position of public analyst, the necessary arrangements have been
made and examiners duly appointed ; so far, however, no
candidates have presented themselves for examination. In previous
reports the Board has expressed its appreciation of the valuable
aid to state education rendered by the Melbourne College of
Pharmacy, which is every year extending its sphere of usefulness,
and now provides for the educational curriculum of pharma¬
ceutical chemists and dentists, as well as the teaching of pharmacy
to medical students of the Melbourne University. The teaching
has been distinguished by zeal and ability, and the personnel of the
staff is said to leave nothing to be desired. The number of
registered apprentices on December 31 last was 565, whilst the
pharmaceutical chemists numbered 1193. Of the latter, 139 were
registered under certificates from the Pharmaceutical Society of
Great Britain, 16 under those of the Irish Society, 14 held foreign
diplomas, and 116 have been registered by virtue of having been
in business at or before the passing of the “Pharmacy Act, 1876.”
The Question of Reciprocity of Certificates has again
occupied the attention of the Victoria Board, and a lengthy
correspondence has taken place with the Pharmacy Board of
Queensland, which invited the Victoria Board to join with it
in asking the Pharmaceutical Society of Great Britain to
recognise the certificates issued by the several colonial Pharmacy
Boards. As far back as July, 1881, a letter was addressed to the
Pharmaceutical Society of Great Bri tai n by the Victoria Board, asking
that recognition might be made of persons holding the examination
certificate of the Board as a qualification for registration in Great
Britain, and to that communication a reply was received that there
were no statutory provisions under the Pharmacy Acts of Great
Britain empowering the Registrar to place any name on the
Register, excepting on the production of certificates of skill and
competency signed by the respective Boards of Examiners
appointed by the Council of the Pharmaceutical Society of Great
Britain and approved by the Privy Council. While the Victoria
Board holds the view that the colonies could not intelligently join in
the Queensland proposal to ask Great Britain to accept certificates
which they themselves refuse to interchange, it is not easy to find
a practical solution of the more important question of intercolonial
reciprocity. The real difficulty is said to be found in the want of
a common intercolonial examination. “Equality of standard of
questions would not be sufficient. There must also be equality of
judgment upon the answers of the students. In the answers of
the students, and the character and conduct of the examinations
will be found the satisfactory evidence as to the value of the
diploma, rather than in the character of the papers.” And it is said
to be clear enough that the papers should be judged by a common
tribunal, else what was accepted or rejected by one set of
examiners might be differently dealt with by another. In the
opinion of the Board the only practical means of establishing inter¬
colonial reciprocity is to be found in an agreement among the
colonies as to a common examination paper and examination.
It is thought that, were this agreement brought about, reciprocity
would practically be achieved.
The Streatham, Balham and Tooting District now has a
chemists’ association, which was inaugurated by the local
chemists at a meeting held on Thursday, May 13. Mr. Robinson,
the oldest established chemist of Streatham, was elected President ;
Mr. Shacklock, Vice-President ; and Mr. Laws, Honorary Secretary ;
The Association has been established for discussing and adjusting
the various matters that may arise from time to time in connection
with the trade locally, and the annual fee has been fixed at the
nominal sum of half-a-crown, whilst all chemists in business for them¬
selves in the above district are eligible for membership on applica¬
tion. Managers of branches desirous of membership should apply
to the officers, and the election will be decided by the Executive.
Chemists in the district should find much benefit from joining
the Association, the next meeting of which will take place on
Thursday, the 27th inst., at 9.30 p.m. The agenda of the meeting
includes a discussion on prices to be charged for dispensing.
In the Manufacture of Dyes, observes the Saturday Review,
the Germans have contrived to show us a clean pair of heels. The
Farbenfabriken (Freidrich Bayer and Co.), of Elberfeld, made a
profit last year of £266,800, and has just paid a dividend for the
year of 18 per cent. The Badische Anilin und Soda Fabrik, of
Ludwigshaven, on the Rhine, had a profit of £400,938, and has
distributed 26 per cent. ; and Messrs. Meister, Lucius, and Bruning,
of Hochst-am-Main, came out with £341,555 to the good, and have
been enabled to return 28 per cent. These several results were
accomplished in spite of injury done by the Presidential election
in America and by the famine and plague in India. What English
dye-making concern, it is asked, can boast of profits equally good ?
“No one can be surprised at the ever-increasing business of these
German firms who has made acquaintance with their murderous
energy, and has contrasted their sample sheets, their pertinacity,
and their terms with the methods of English manufacturers.
Scarcely a week passes but they offer you something new. They
employ large staffs of highly-trained and highly-paid chemists who
450
PHARMACEUTICAL JOURNAL.
[May 22, 1897
spend their time on novelties and the improvement of existing
products. In other words, they know their business thoroughly.”
As being likely to help to a better notion of the German superiority
in this particular, it is stated that Germany sent to the United States
during the twelve months ended June last 9,763,080 lbs. of alizarin
against 308,743 lbs. sent by us, while of coal-tar colours and dyes
the imports from Germany were valued at §2, 324, 157, and those from
Great Britain at $191,263.
Poisoning by Linimentum Belladonna was recently caused
in the case of a lady, aged 53, who during the night measured
into a medicine glass a tablespoonful of the liniment in mistake
for a bromide mixture, which she had occasionally taken. She
discovered her error after swallowing it, but not knowing the
dangerous character of the preparation, retired to bed.
Subsequently she was discovered to be suffering from poisoning,
and placed under treatment, with the result that she recovered.
The medical man who records this case in the British Medical
J oumal thinks it desirable to place the case on record inasmuch as
the portion of the drug taken was a known quantity, and he also points
out that, owing to, what he terms, the careless dispensing of half
a pint of this powerful liniment by a firm of chemists in a neigh¬
bouring town in “an ordinary half-pint medicine bottle,” a valu¬
able life was for a time placed in jeopardy. If the facts be as
stated, the matter is certainly one for considerable regret.
Monsonia Ovata is used in South Africa for dysentery, but
there appears to be some doubt as to the species employed. Mr.
J. Medley Wood, A.L.S., Curator of the Botanic Gardens, at
Durban, Natal, states that the plant which was pointed out to
him as the one used for dysentery by two residents in the Orange
Free State was Monsonia biflora, and not M. ovata. The latter does
not grow in Natal, but in the Drakensberg mountains.
“ Pharmaceutical Secrets ” is the heading of a letter to the
Daily Graphic signed by “A Licentiate of the College of
Physicians,” who is alarmed because a pharmaceutical writer has
contended that medical secrets become eventually pharmaceutical
secrets, and that any rights or privileges granted to the doctor
should be extended to the pharmacist, since the “secret” is his
as much as the doctor’s. This communication is said to open up
alarming possibilities, “ showing as it does that the confidences
of the invalid are not reposed in the physician alone, but also by a
side issue in a tradesman who is bound by no law of honour or
custom to keep his secret.” This new medical alarmist is good
enough to say that he does not pretend that chemists are in the
habit of betraying confidences, but he does think that the public
should appreciate “ this anomalous condition.” Naturally, he
finds it is easier to point out an evil than to suggest a remedy,
but he thinks the state of things he imagines to exist could be
controlled by making it illegal for a chemist to give a copy of, or
state the contents of, a prescription without an express order
from the prescriber. In spite of the backwardness of the season,
it would appear that the big gooseberry is already upon us.
Mr. George Claridge Druce, whose genial personality com¬
mends itself to so many pharmaceutical friends, is, as is well known,
the present Sheriff of Oxford and Conservator of Port Meadow
and the Fisheries. Mr. Druce was born in Northamptonshire, and
after following the profession of pharmacy for some years —
during which he acted as president of the Northampton
Pharmaceutical Association, and honorary secretary of the
Northampton Natural History Society— he proceeded to Oxford,
where he was mainly instrumental in founding the Oxfordshire
Natural History Society, of which he was elected president in 1895
and 1896. He was elected on the City Council in 1893, and was.
local secretary to the British Association on the occasion of the
meeting in Oxford in 1894. For some years Mr. Druce was on
the Examining Board of the Pharmaceutical Society, and his.
labours in connection with botanical science are familiar to all
our readers. In recognition of the value of his work upon the
‘ Flora of Oxfordshire,’ published in 1885, the University of Oxford
conferred upon him the honorary degree of Master of Arts. Mr.
Druce is at the present time president of the Oxford and District
Chemists’ Association, and curator of the Fielding Herbarium at
Oxford. He has recently come somewhat prominently before his
fellow-citizens in connection with the opening of the Oxford
Municipal Buildings by the Prince of Wales, and at the last
meeting of the City Council Mr. Druce generously presented the
Corporation with a handsome gold chain for the use of future
Sheriffs, in commemoration of the record reign.
Postal Reforms Come Thick and fast nowadays. Only a,
fortnight ago we were able to announce approaching changes of an.
almost revolutionary character, when viewed from the official
red-tape point of view, and now similarly progressive arrange*
ments have been concluded with the Postmaster-General in con*
nection with the telephone service. Thus, a number of post-offices
in the London postal area connected to the exchanges of the
National Telephone Company (Limited) will, on and after June 1
next, be enabled to telephone a message, for : (a) transmission
over the postal telegraphs and delivery as a telegram ; ( b ) delivery
as an express letter ; (c) conveyance and delivery as an ordinary
letter ; or (d) calling for the services of a post-office express
messenger. Amateur postal reformers are being anticipated to-
such an extent that there might be fear of their occupation
vanishing were it not that such a mountain of official prejudice
yet remains to be overturned.
The True Pharmaceutical Chemist, observes a writer in the
Scalpel, deserves all possible protection and encouragement from
the medical profession. But as to the wholesale chemist, he mush
“ choose whether he will devote himself to the profession or to the
public. If he tries to sit on two stools at the same time he will
fall between the two, and very deservedly.” A distinction is drawn
between manufacturers of special preparations which are non-
secret and really contain what is represented to be present, and
those who endeavour to thrust upon the profession and the public
proprietary remedies of unknown composition. In conclusion, it
is pointed out that neither medical nor pharmaceutical science is
advanced by ordering “ Banaline or sammittine and other such
products,” whilst patients are not treated scientifically or even
fairly when medical practitioners recommend to them proprietary
medicines about which they know nothing. The remedy is said
to be in the hands of medical men and pharmacists ; if those two-
classes are not content with the existing state of things, “ then let
us have some action to voice the discontent.”
The Chemists’ Exhibition for 1897 is to be held in Covent
Garden Theatre, and we are requested to state that the whole of
the space available for stands in the auditorium and on the stage
of the theatre having been taken, arrangements have been made
to hold an overflow exhibition in the large saloon of the theatre on
the first tier. The stands already arranged for will, it is stated,
comprise the largest and most varied display of exhibits which
has ever been collected for the inspection of pharmacists.
May 22, 1897J
PHARMACEUTICAL JOURNAL
451
LIST OF DONATIONS AND SUBSCRIPTIONS
IN AID OF THE
BENEVOLENT FUND.
The following donations and new or increased annual subscriptions were
announced at the Festival Dinner on Tuesday last (see report at page 431).
Furtherjcontributions are solicited, and listsof the same will be published shortly;—
Dons. Subs.
Abraham, A. C. ; 87, Bold Street, Liverpool . 2 2 0
Allen, C. B. ; 20, High Road, Kilburn, N.W . 5 5 0
Apollinaris Company, 4, Stratford Place, W . 10 10 0
Arkinstall, W. ; Burnaby Gardens, Chiswick, W . 5 5 0
Amfield, J. C. ; 7, Lower Hillgate, Stockport . 1 1 0
Atkins, S. R. ; Market Place, Salisbury . . . 5 5 0
Atkinson, Leo ; 285, Brockley Road, S.E . . 1 1 0
Attfield, Dr. John ; Ashlands, Watford . 21 0 0
Ault, John ; TJsk, Mon . 1 1 0
Austin, H. F. ; 126a, Bermondsey Street, S.E . . 2 2 0
Ayrton and Saunders, 149, Duke Street, Liverpool ....... 2 2 0
Baiss, Arnold ; 4, Jewry Street, E.C . 5 5 0
Baiss Bros, and Co. ; 4, Jewry Street, E.C . . 10 10 0
Barron, Harveys and Co. ; 6, Giltspur Street, E.C . 10 10 0
Bascombe, F. ; 2, Onslow Gardens, Highgate, N . 2 2 0
Bate, H. ; 125, South Lambeth Road, S.W . 1 1 0
Bateman, T. H. ; 223, Finchley Road, N.W . 1 1 0
Bates, F. W. ; Brook’s Bar, Manchester . 1 1 0
Bates, J. ; Wellington, Salop . 5 5 0
Bateson, T. ; 23, Stricklandgate, Kendal..-. . . 110
Beard, J. H. ; Great Ancoats Street, Manchester . . 110
Bell, C. B. ; 6, Spring Bank, Hull . 1 1 0
Bell, W. H. ; 96, Albany Street, N.W . 1 1 0
Benger, F. Baden ; Manchester . 100 0 0
Berkefeld Filter Co. ; 121, Oxford Street, W . 1 1 0
Bessell, Walter ; 13, Belle Vue Road, Upper Tooting, S.W. 5 5 0
Bew, J. ; 8, Willow Bank, Manchester . 2 2 0
Bird, Augustus ; Wood Lane, Shepherd’s Bush, W. . . . . 21 0 0
Blackburn, A. E. H. ; Beaconsfield, Eccles . 1 1 0
Blake, Sandford and Blake ; 47, Piccadilly, W . 5 5 0
Bly ton and Astley ; Lower Broughton, Manchester ... 5 5 0
Bolton, C. A. ; 40, Carlton Street, Nottingham . 1 1 0
Booth, E. ; 5, Chester Bridge, Crewe . 1 1 0
Bottle, Alexander ; Dover . 5 5 0
Bourdas, I. ; 48, Belgrave Road, S.W . 21 0 0
Bourne, Johnson, and Latimer ; 35, Fumival Street, E.C. 110
Boutall, G. S. ; Marchmont Street, W.C . 1 1 0
Bowen, J. W. ; 13, Curzon Street, W . . . 2 2 0
Bowerbank, J. ; Castlegate, Cockermouth . 5 5 0
Bowker, J. T. ; Westfield House, Farnworth . . . 1 11 6
Bradford Chemists’ Association, per Mr. Waddington,
Local Secretary (proceeds of Mr. Howie’s lecture) . . 10 10 0
Bridge, G. E. ; 128, Christchurch Road, Bournemouth . . 5 5 0
Bristol Pharmaceutical Association . 5 5 0
Bristow, T. F. and Co. ; Clerkenwell, E. C . 5 5 0
British and Colonial Druggist, Proprietors of . 105 0 0
Brodie, R. ; 253, Crown Street, Glasgow . 160
Brown, A. J. ; 55, Trafalgar Road, Greenwich, S.E . 10 10 0
Burgoyne, Burbidges and Co. ; Coleman Street, E.C..... 10 10 0
Burroughs, Wellcome and Co. ; Snow Hill Buildings, E.C. 105 0 0
Butt, E. N. ; 77, Hamilton Terrace, Maida Vale, N.W. .. 42 0 0 15 15 0
Cadman, D. C. ; 6, Royal Parade, Blackheath .......... 220
Calvert, F. C., and Co. ; Bradford, Manchester . 5 5 0
“ Camwal” Directors ; 45, Gifford Street, N . 50 0 0
Carteighe, Michael ; 180, New Bond Street, W . 10 10 0
Chaplin, J. H. ; 60, Westgate, Wakefield . . 1 1 0
Chaplin, W. H. and Co. ; 10, Villiers Street, Strand, W.C. 2 2 0
Chemist and Druggist, Proprietors of . 105 0 0
Chemists’ Ball Committee . 105 0 0
Che verton and Ogle ; Tunbridge Wells . . . 110
Clark, J. A. ; 48, Broadway, London Fields, E . 5 5 0
Clark, R. U. ; 14, Kent Street, Jarrow-on-Tyne. . 110
Clarke, J. ; 38, George Street, Croydon . 2 2 0
Clay, Dod, and Co. ; 52, St. Anne Street, Liverpool . 110
Clough, J. C. ; High Street, Northwich . 110
Collie, Professor; 16, Campden Grove, W . . 2 2 0
Dons. Subs.
Collier, H. ; Guy’s Hospital, S.E . 2 2 0
Cook, E. and Co. ; East London Soap Works, Bow, E. . . 110
Cooperand Co. ; 80, Gloucester Road, S.W . 10 10 0
Corbyn, Stacey, and Co., 22, Gt. St. Helens. E.C . 5 5 0
Cornelius, R. B. ; Oak Cottage, Teignmouth . . 110
Cracknell, H. ; 17, Craven Road, W. . . . 2 2 0
Crafton, R. F. ; Bramley Hill, Croydon . 1 1 O
Cresswell, F. ; 133, Burnt Ash Road, Lee, S.E . 2 2 0
Currie, W. L. ; 223, Byres Road, Glasgow . . Ill 6
Curtis and Co. ; 48, Baker Street, W . 1 1 0
Dakin, J. Harrison ; 87a, Leadenhall Street, E.C . 2 2 0
Davenport, Horace ; 33, Great Russell Street, W.C . 5 5 0
Davenport, J. T., 33, Great Russell Street, W.C . 10 10 0
Davenport, Rev. John M. ; St. John, New Brunswick ... . 5 0 0
David A. ; Cross Square, St. Davids . 1 3 6
Davidson, A. ; 172, High Street, Montrose . 3 3 0
Davis, J. Morgan ; 7, Princess Buildings, Coventry St.,W. 110
Davy, Hill and Son, Yates and Hicks ; 101, Southwark
8treet, S.E . . . . . 10 10 0
Deakin, J. W. ; 40, Witton Street, Northwich . 110
Dennis and Roberts ; Nottingham . 1 1 0
Dieterich, Eugen ; Helfenberg, near Dresden . 3 3 0
Dinneford and Co. ; 180, New Bond Street, W . . 10 10 0
Dodd, R. J. ; 70, Tottenham Court Road, W. . 10 10 0
Druce. G. C. ; 118, High Street, Oxford . 21 0 0
Duncan, Flockhart and Co. ; Edinburgh . 26 5 0
Dyson, W. B. ; Gloucester Road, S.W . 2 2 0
Eade, G. ; 72, Goswell Road, E.C . 5 5 0
Bastes, E. J. ; 61, Chancery Lane, W.C . 1 1 0
Evans, D. O. ; West Street, Ashburton . 1 1 0
Evans, Lescher and Webb ; 60, Bartholomew Close, E.C. 10 10 0
Evans, Sons and Co. ; Hanover Street, Liverpool . 52 10 0
Ewing, J. Laidlaw ; 52, North Bridge, Edinburgh . 10 10 0
Farr, E. H. ; Uckfield . . 110
Flux, Thompson and Flux ; 3, East India Avenue, E.C. 10 10 0
Francis, G. B. ; 38, Southwark Street, S.E . 5 5 0
Francis, W. H. ; 38, Southwark Street, S.E . 5 5 0
Frazer, D. ; 127, Buchanan Street, Glasgow . 1 1 0
Frost, J. H. ; High Street, Hornsey, N . 5 5 0
Frost, W. T. ; Ingle ville, Parson’s Green, S.W . 2 2 0
Gavin, Thomas; 31, Bristol Street, Hulme, Manchester.. 110
Gibbs, W. ; St. Heliers, Ryde, I.W . . . 1 1 0
Gibson, R., and Sons ; Erskine Street, Manchester . 5 5 0
Gill, W. ; 207, Radford Road, Nottingham . 1 1 0
Goodall, Backhouse, and Co. ; Leeds . 10 10 0
Gossling, W. R. ; 7, The Strand, E. Southsea . 110
Gostling, J. H. ; Halesworth . . . . 1 1 0
Gostling, T. P. ; Diss . 5 5 0
Greenish, Professor ; 20, New Street, N.W . 1 1 0
Greenish, T. ; 20, New Street, N.W . 1 1 0
Gregory, W. ; Weymouth . 2 2 0
Grimwade, E. H. ; Croydon . 5 5 0
Grimwade, Hon. F. 8. ; Melbourne . 5 5 0
Grose, N. M. ; 8, Temple Street, Swansea . 2 2 0
Groves, T. B. ; Belmont, Seldown, Poole .... 1 1 0
Gulliver, W. F. ; 6, Lower Belgrave Street, S.W . 1 1 0
Hampson, Robert ; Norland House, Sevenoaks . 5 5 0
Hanbury, Cornelius ; Plough Court, Lombard Street, E.C. 26 5 0
Hardcastle, 8. B. ; 71, East Street, Brighton . 1 1 0
Hardie, J. and Son ; Dundee . 1 1 0
Hare, G. E. ; 8, London Road, Nottingham . - . . 1 1 0
Harley, E. T. ; 262, Mare Street, Hackney, N.E . 5 5 0
Harrington, J. F. ; 45, High Street, Kensington, S.W. .. 110
Harrison, John ; 33. Bridge Street, Sunderland . 5 5 0
Harvey W, K , ^umston Lodge, Leicester . 2 2 0
Hearon, Squire, and Francis; 38, Southwark Street, S.E. 26 5 0
Hebbeler, K. ; 121, Oxford Street, W . 1 1 0
Heighington, T. G. ; 33, Hill Street, Rutland Gate, S.W. 110
Hertz and Collingwood ; 38, Leadenhall Street . 11
[Mat 22, 1897
452
P3 ARM ACEUTTCA L JOUR X A L.
Dona. Subs.
Hewlett, James ; 26, Ethelbert Road, Margate - . 5 5 0
Hills, Walter ; 225, Oxford Street, W . 10 10 0
Hobbs, A. E. ; Tunbridge Wells . . 1 1 0
Hoekin, Wilson, and Co. ; 14, New Inn Yard, W . 5 5 0
Hodgkinsons, Treacher, and Clarke ; WhitecroSs St., E.C. 10 10 0
Hogg, A. ; Leven . 1 10 0
Hogwood, E. ; Plough Road, Rotherliithe, S.E . 1 1 0
Holford, T. C. ; a42. High Street, Stratford . 5 5 0
Holmes, E. M. ; Sevenoaks . . , . 11 0
Hojikin, W. King; Fern Brae, Brondesbury Park, N.W. 15 15 0
Horner and Sons ; Mitre Square, E.C . , 110
Horsley, J. ; 104, High Street, Hartlepool . 5 5 0
Hough, T. ; 57, Station Road, Northwich . . 110
Howell, M. ; SI, High Street, Peckham, S.E . 1 1 0
Howie, W. L. ; Monton Lodge, Monton, Eocles . 10 10 0
Humphreys, G. ; 44, High Street, Northwich . 110
Hunt, Richard ; 71, Parliament Hill Road, N.W . 5 5 0
Idris and Co. ; Pratt Street, Camden Town, N.W . 10 10 0
Ingram and Royle ; 26, Upper Thames Street, E.C . 10 10 0
Jacks, D. R. ; 161, Gower Street, W.C . 1 11 6
Jackson, G. ; S70, Rochdale Road, Manchester . 1 1 0
Jewsbury and Brown; Ardwick Green, Manchester .... 10 10 0
John, B. ; Old Bond Street, Bath . 1 1 0
Johnson, J. H. and S. ; Whitechapel, Liverpool . 5 5 0
Johnstone, C. A. ; Victoria Bridge, Manchester . 5 5 0
Jones, W. ; 2, High Street, Birmingham . . . 1 1 0
Kay, S. and T. ; Stockport . 2 2 0
Kemp, D. S. ; 52, Coverdale Road, Shepherds Bush, W. . . 2 2 0
Kemp, Harry ; 254, Stretford Road, Manchester . 1 1 0
Kirkby, Wm. ; 113, Market Street, Manchester . 110
Knott, H. ; 1, Blackburn Road, Bolton . 5 5 0
Lane, W. ; Whalley Range, Manchester . . 1 1 0
Lansdown, G. A. ; 5, Warwick Street, Charing Cross, S.W. 110
Lee, W. ; Castle Northwich . . 1 l o
Lidwell, J. E. ; 257, Vauxhall Bridge Road, S.W . 1 1 0
Lorimer and Co. ; Britannia Row, Islington, N . 21 0 0
Lucas, E. W. ; 225, Oxford Street, W . . . 8 3 0
MacEvvan, Peter ; 42, Cannon Street, E.C . 2 20
Macfarlan, J. F., and Co. ; Moor Lane, Fore Street, E.C. 10 10 ,0
Marsh, E. R. ; 73, Salusbury Road, N.W . . . 1 1 0
Martindale, William ; 10, New Cavendish Street, W . 5 5 0
Mather, W., Limited ; Manchester . 5 5 0
Mathews, J. and II. ; 6S, Queen’s Gardens, Hyde Park, W. 5 5 0
Mayger, W. D. ; Regent Square, Northampton . 1 1 0
Meggeson and Co. ; 14, Miles Lane, E.C . . .. .. 21 0 0
Morson, A. ; Southampton Row, W.C . 5 5 0
Morson, T. and Son ; Southampton Row, W.C. . . . 10 10 0
Moss, John ; Wilson Street, New Cross, S.E . 5 5 0
Naylor, W. A. H. ; 3S, Southwark Street, S.E . 5 5 0
Newbery, Francis and Sons ; 1, King Edward Street, E.C. 5 5 0
Newsholme, G. T. W. ; 27, High Street, Sheffield _ 5 5 0
Oldfield, Pattinson and Co. ; Todd Street, Manchester . . 5 5 0
Paine, Standen ; Manchester . 21 0 0
Parke’s Drug Stores, Managing Director of . 5 5 0
Parkinson and Son ; Southampton Row, W.C . . 5 5 0
Parrott, J. ; 50, Friars Stile Road, Richmond, Surrey . . 110
Peck, E. S. ; Cambridge . 1 1 0
Peck, E. ; East Dereham . 1 1 ft .
Perkins, T. J. ; Beckenham . 1 1 0
Peters, D. ; 165, Fortess Road, N.W . . 1 1 0
Phillips, A. J., 156, Cromwell Road, S.W . 2 2 0
Pidd, A. J. ; 221, Chester Road, Manchester . . 1 1 0
Pierce, Tulley and Co. ; 16, Bishopsgate Street Within, E.C. 110
Pinchen, W. J. ; 229, High Road, Kilburn, N.W . 1 1 0
Pitman, John ; Redcliffe Hill, Bristol . 5 5 0
Plumbly, W. ; Newmarket Place, Beccles . 160
Portway, A. C. ; 189, Wandsworth Road, S.W . 1 1 0
Potter, A. W. G. ; King Street, E.C. - . 2 2 0
Potter and Clarke ; Artillery Lane, E . . . 6 5 0
Prior, G. T. ; 45, Holywell Street, Oxford . 1 1 0
Pritchards, Ltd. ; Manchester . 1 1 0
Probvn, Major Clifford ; 55, Grosvenor Street, W . 105 0 0
Radford, J. S. ; 10, Derby Road, Nottingham „ . 1 1 0
Ransom, F. ; Hitchin . . . , . 5 5 0
Ransom, W. ; Hitchin . 5 5 0
Reynolds and Branson ; 13, Briggate, Leeds . 10 10 0
Dons. Subs.
Reynolds, R. J. ; Manchester . 1 1 0
Richards, F. J ; Dudley Road, Birmingham . 1 11
Richards, J. M. ; 46, Holborn Viaduct, E.C . 1 1 0
Richardson, W. I., 4 and 5, Great Queen Street, W.C. .. 5 5 0
Robbins, John ; 147, Oxford Street, W . 10 10 0
Roberts, W. R. ; Rusholme, Manchester . 1 1 0
Robertson, G. ; Woodford . . . 110
Robinson, B. ; Pendleton, Lancs . . ,... 2 2 0
Robinson, R. A. ; 195, Brompton Road, S.W . . 5 5 0
Robinson, W. P. ; 17, Pavement, Clapham Common .... 220
Rogers, F. A. ; 327, Oxford Street, W . 1 11 6
Ross, A. L. ; 21, High Street, Montrose . 5 5 0
Rundle, C. ; 24, Russell Straet, Covent Garden, W.C . 110
Sadler, W. ; 257, Evering Road, Upper Clapton . 2 2 0
Savory and Moore ; 143, New Bond Street, W . 21 0 0
Saxlehner, A. ; Buda-Pest . 5 5 0
Sayers, W. C. ; 63, High Street, Lewisham . . 5 5 0
Selley, J. ; 142, Earl's Court Road, S.W. . . 1 1 0
Sergeant, F. R. ; 11, Beast Market Hill, Nottingham - . 1 1 0
Sewelson, D. ; 39, Cheetham Hill Road, Manchester .... 1 10
Siebold, L. ; Sale . 1 1 0
Simpson, H. D. ; Louth . 1 1 0
Slinn, H. E. ; 10, Northgate Street, Gloucester.. _. . 1 1 0
Smith, S. and Co. ; Malmesbury Road, Bow, E . 5 5 0
Smith, T. and H. and Co. ; 21, Duke Street, Edinburgh.. 5 5 0
Smith, W. ; 2, Linsey Street, Bermondsey, S.E . . 1 11 6
Southall Bros, and Barclay ; 17, Bull Street, Birmingham 10 10 0
Stanley, J. ; 2, Crown Street, Nottingham . 1 1 0
Starkie, R. S. ; 126, Strand, W.C . 1 1 0
Stead, J. C. ; Leytonstone . . 1 1 0
Stevens, P. A. ; 72, Mansfield Road, Gospel Oak , N.W. . . 2 2 0
Stickland, G. G.; 23, Cromwell Place, S.W . 1 1 0
Storey, E. H. ; 42, Castle Street East, W . 1 1 0
•torrar, D. ; 22S, High Street, Kirkcaldy . 2 2 0
Sumner and Co. ; Lord Street, Liverpool . . . . . . 2 2 0
Sunman, J. T. ; 43, Wellington Street, Luton . 160
Symes and Co. ; 14, Hardman Street, Liverpool . 5 5 0
Taylor, G. S. ; 13, Queen’s Terrace, St. John’s Wood, N.W. 2 2 0
Thompson and Capper ; Bold Street, Liverpool - . 1 1 0
Thomson, W. ; Hillhead, Glasgow . 1 6 0
Thorn, J. J. ; 225, Oxford Street, W . .. . 8 3 0
Tocher, R. ; Maybole . 1 1 0
Toye, J. ; 5, Bonner Street, Bethnal Green, E . 110
Truman, F. W. ; 71, Old Kent Road, S.E . . 1 11 6
Turner, E. A. ; 2S0, Fulham Road, S.W . 4 4 0
Umney, C. ; 50, Southwark Street, S.E . 5 5 0
Vallance, A. C. ; Mansfield . . .. 1 1 0
Wade, J. ; 174, Warwick Street, Pimlico, S.W . 1 1 0
Waring, A. W. ; 3, Bucklersbury, E.C . . . . . . . 1 1 0
Warren, W. ; 24, Russell Street, Covent Garden, W.C. .. 3 3 0
Warrick, F. W. ; 7, Portpool Lane, E.C . 5 5 0
Waterall, G., and Son ; Nottingham . . . . 110
Weaver, A. C. ; Wolverhampton . . . . . ...... 1 11 (5
Westmacott, G. H. ; 17, Market Street, Manchester _ 110
Weston, S. J. ; 151, Westbourne Terrace, W . 1 1 0
Whiff en, Thomas ; Lombard Road, Battersea . . .. 21 0 0
Whiffen, T. J. and W. G. ; Lombard Road, Battersea - 5 6 0
Widdowson, R. ; 43, Mansfield Road, Nottingham . 1 1 0
Wigginton, A. ; 137, Sloane Street, S.W . 1 1
Wilford, J. ; Parliament Street, Nottingham . 1 1 0
Wilkinson, J. F. ; Manchester . 5 5 0
Will, W. W. ; 162, Kennington Park Road, S.E . 2 2 0
Wilson, J. ; 76, Finsbury Pavement, E.C . 1 1 0
Wink, J. A. ; Devonshire Square, Bishopsgate, E.C . 5 5 0
Woolley, G. S. ; Victoria Bridge, Manchester . 10 10 0
Woolley, Hermann ; Victoria Bridge, Manchester . 10 10 0
Wootton, A. C. ; 42, Cannon Street, E.C . I _ 10 10 0
Worfolk, G. W. ; Brook Street, Ilkley . 1 11 6
Wretts, J. R. ; 225, Oxford Street, W . 3 3 0
Wright, A. ; Yeovil . . . . . . 2 2 0
Wright, G. B. ; Hebden Bridge . 1 1 •
Wright, Layman and Umney ; 50, Southwark Street, S.E. 10 10 0
Yates, C. G. ; 21, Upper Hamilton Road, Brighton . 1 1 0
Young, J. Rymer ; Sankey Street, Warrington . 6 6 0
Young, R. Fisher ; Station Road, New Barnet . 2 2 0
Other contributions of smaller sum» amounting to . 145 19 6
May 22, 1897]
PHARMACEUTICAL JOURNAL.
453
THE WORLD Op PHARMACY.
■ - ♦ - -
BUSINESS MEETINGS.
Apothecaries’ Society. — A course of lectures was com¬
menced on Tuesday, May 11, by Professor F. W. Oliver, of
University College, London, on
The Diseases op Plants.
The lecturer dealt in this first lecture with the host and parasite,
pointing out that the host or plant attacked was liable to a wide
variation in health dependent in large measure on external con¬
ditions. As a consequence, when as a result of the checking of
important functions the host possessed a lowered vitality, it became
more liable to attack than when its members were able to discharge
their functions in a requisite manner. The changes in the tissues
resulting from this lowered vitality were often such as to make
the host plant more liable to attack from a fungal parasite,
and if at the same time the same conditions were favourable
to the fungus (as often happened), the attack would be the
more virulent. A short account was given of the normal
and disturbed functions of the higher plant, as well as
of the effect of various nutritive conditions upon the fungus.
It was also shown that plants in many cases are especially liable
to attacks by parasitic fungi at certain restricted periods in their
lives, and that if they successfully passed through such critical
periods they would in all probability resist attack. The methods
of entry of fungal hyphse into the tissues and their action on the
living cells were described. Yery interesting in this connection is
the fact that in certain cases ( e.g ., Botrytis) the fungus can pass
from the condition of a saprophyte to that of a parasite ; and its
conidia, which at first are harmless where living tissues are con¬
cerned, will after a few generations, nourished saprophytically, be
able to germinate on a living host and invade its tissues.
The subject selected for treatment in the second lecture, on
May 18, was
The Witches’ Broom.
The classical instance of the witches’ broom on the silver fir,
caused by the fungus, JEcidium elatinum, was described as a type
of peculiar response to stimulus on the part of the host plant.
The group of structures comprehended under this term was ex¬
tended so as to include a large number of hypertrophies, involving
either parts or even the whole of the plant attacked when the
pathological growth in question exhibited a modification of the
normal plant habit. As further instances of local hypertrophy
following attack by members of the family of Uredineie, were quoted
swellings on the pine, due to Peridermium pini, and similar
structures on the juniper, due to Gymnosporangium. Instances
of complete hypertrophy of the whole plant included Euphorbia
cyparissias by Uromyces pisi, and the house-leek by Endophyllum
sempervivi. The group of the Exoascacese was next dealt with, the
genus Exoascus being remarkable for the witches’ brooms which it
produces on common trees, such as the birch, alder, and cherry.
The life-history of a typical member was described, and the
relations existing between the fungus and the peculiar nest-like
hypetrophies which it causes pointed out. Allusion was made to
a lately-cited instance of hornbeams producing twigs with oak¬
like foliage and their possible connection with an invading fungus
discussed, whilst ferns also were shown to be not entirely free
from the excrescences in question. Finally the biological meaning
of witches’ brooms was discussed, the view being expressed that
in many cases they represented an effort on the part of the plant
attacked to localise the area of attack. The lecture was very
fully illustrated by specimens and lantern slides.
Midland Pharmaceutical Association, Wednesday,
May 12. — The Trade Committee of this Association has issued its
annual report, in which it is stated that during the year five meet¬
ings have been held under the chairmanship of Mr. W. Jones.
The Committee has had under consideration the best way of
strengthening the P.A.T.A., which association it is convinced will
be the means of not only securing to the retailer an adequate
remuneration, but also of forming the basis of a strong
and united trade protection association. The Committee has
had correspondence with all the leading wholesale houses who
had not yet joined the P.A.T.A., and in most cases has been
able to influence them to reconsider their position. It has
also corresponded with all the leading makers of proprietary
articles, who still held aloof from the association, and it is found
that most of them, while admitting that the principle of a
guaranteed profit was a just one, are waiting developments before
they join. The Committee has opened negotiations with the
London carriers re carriage of small parcels at a reduced monthly
rate to members of the association, and it is hoped the issue
will be satisfactory. It is recorded with pleasure the
fact that the Chairman — Mr. Wm. Jones — was unani¬
mously elected President of the P.A.T.A. , having headed the
poll at the election of the retail section. The Committee offer
the following recommendations to the members of the Association -
—That every member should not only join the P.A.T.A.,.
but should use every legitimate effort to persuade all the whole¬
sale houses he dealt with to join also ; that members should also-
use every effort to induce the makers of proprietary articles,
especially those from whom they bought direct, and with whom
they had any influence, to place their articles on the protected list j
that members should protest strongly against any individual
scheme for protecting proprietary articles, past efforts in that
respect showing absolute failure and annoyance, besides entailing
unnecessary work and trouble, all of which could be avoided by
placing the articles on the protected list, at the same time¬
strengthening and consolidating their efforts. It was further
suggested that at the annual meeting a resolution be passed
and forwarded to all the firms who have assisted them in their
work, thanking them for their support and promising them hearty
co-operation in the future. The Committee is glad to report that the
feeling of the trade in Birmingham and district is entirely with it.
in its efforts, and it is felt that the Committee can confidently rely
upon their united support. It was suggested that members should
vote solid for the candidates in the forthcoming Pharmaceutical
Council election who were in sympathy with the P.A.T.A. Mr.
F. H. Prosser had continued in _ the position of Secretary to the
Committee.
Midland Chemists’ Assistants’ Association, W ednes-
day, May 12. — Mr. H. S. Lawson, President, in the chair. — The
annual meeting of the Association was held at the Exchange,
Birmingham. — The President, in opening the proceedings, con¬
gratulated the members on the work they had done during the
session. They had, he felt sure, done an amount of useful and
interesting work on behalf of the craft. They had held meetings
at which scientific subjects had been discussed, and their social
meetings had been also a great success — Mr. Bindloss (Hon.
Secretary) then presented the
Report of the Committee,
which stated that during the session thirteen new members had
been enrolled, and the membership was now seventy-two
ordinary, twelve honorary. The donors had increased from
one to nine. Twenty-seven meetings had been held, in¬
cluding eight social, the annual ball and dinner. Thir¬
teen papers had been read on subjects of great interest to-
them, and at one of the meetings a resolution was passed approving
of the objects of the P.A.T.A. A discussion had also taken place
on the proposed new bye-laws. — On the motion of Mr. Oasson,
seconded by Mr. Walton, the report was approved.— Mr.
Shorthotjse stated that the balance sheet was in the hands of the
printers, and therefore he could not present it to the meeting.
The receipts, however, amounted to £26 4s. 2d. , and there was a
balance in favour of the Association of £7 3s. O^d. — The Chairman
remarked that it was eminently satisfactory to have a balance,
sheet of that kind, because it was something of a novelty for an
association of chemists to have a balance on the right side. All he had
to do was to take farewell of that meeting and the onerous position,
of President of the Association, and he did so with the feeling that
his efforts during the session had not been altogether what he had
hoped for. As they knew, the lot of a pharmacist was a difficult
one, and he had not a great amount of time to give, even to such
objects as were for their mutual benefit. However, he charged
them not to be discouraged by any shortcomings in the President
in the past, but to go boldly forward with the Association and its
work. He had no doubt their work through the session had had.
its weight in the world of pharmacy. They had held meetings an
expressed their opinions on matters pharmaceutical, ant ubon
changes that were proposed. They had also expressec^ the opinion
454
PHARMACEUTICAL JOURNAL.
LMay 22, 1897
that the hours of labour which existed in the trade were not such
as they ought to be. That was a matter clearly within their
province as an association, and they must work more
energetically in the future to secure shorter hours.
They supported the Early Closing Bill in the hope
that it might lead to more reasonable hours of labour.
Another point he desired to mention was the Benevolent Fund.
Everyone of them ought to support that Fund, which required no
special pleading for, but many of them, from indifference or other
reasons, forgot to give it their support. He intended to become
an annual subscriber, and he hoped many of his fellow members
would do likewise. With regard to subscribing to the Pharma¬
ceutical Society, that was a matter which they could not make
compulsory on their members, but he thought it would lend
strength to their Association if larger numbers subscribed to the
.Society. He hoped his successor in that chair would receive
the loyal and consistent support of the members. — Mr. Osborne,
in moving a vote of thanks to the Chairman and 6fficers,
drew attention to the fact that Mr. Bindloss was shortly leaving
Birmingham to take up a position at Shrewsbury. He was
sure they were all sorry to lose Mr. Bindloss, for he had been the
mainstay of the Association, and they wished him every success
where he was going. — Mr. Shorthouse seconded the motion, and
cordially endorsed the remarks respecting the value of Mr.
Bindloss’s services to the Association. — The resolution having been
carried, Mr. Bindloss said that he should always watch the doings
of the Association through the J ournal, and should continue his
interest in its welfare. The report of the scrutineers showed that
the following were elected on the Committee — Messrs. J. W.
Bland, H. Jessop, H. S. Lawton, F. Casson, Walton, E. Osborne,
F. Faulconbridge, F. C. Clarke, H. Boucher, F. Foster, W. E.
Meggison, J. Selby, and A. G. Trow. — A vote of thanks was
passed to the scrutineers, and the meeting terminated.
Plymouth, Devonport, Stonehouse and District
Chemists’ Association (Junior Section), Thursday, May 13.
— Mr. J. A. Buckley in the chair. — A well-attended meeting was
held at the New Rooms, Wimple Street. Among those present
were Messrs. Shakerley, Pratt, Cantle, E. T. Cocks, H. Vibert,
Hellyer, Body, Trenear, Waldon, and Reynolds. — Mr. H. C.
Cantle was unanimously elected junior delegate in place of Mr.
E. A. Hodge. — A long discussion took place on
The New Bye-Laws.
— Mr. Shakerley, in supporting, remarked that in his opinion the
new bye-laws were very desirable, especially so in the case of the
Preliminary examination. He would like to see the Preliminary
so extended that apprentices would be compelled to pass it before
leaving school. W ith regard to the Minor fee, he considered that
by means of the raised fee the Society would be placed in a
better financial position, also it would raise the status
and enable chemists to have a pride in their Society. —
Mr. Waldon considered that it was hardly fair that the present
unqualified man should pay for the registration of the qualified
men who did not belong to the Society at the present time. — Mr.
Cantle said that, although agreeing with the new bye-laws, he
considered that all qualified assistants belonging to the Society
should be entitled to vote. — Mr. Shakerly proposed, and Mr.
Pratt seconded, the following resolution which was carried
unanimously : —
“ That the Plymouth, Devonport, Stonehouse and District Chemists’ Associa¬
tion (Junior Section) approves of the new by e-laws, but is of opinion that
the Minor fee should not be altered until 1900.”
The following Committee was appointed to make arrangements
for a junior outing to take place shortly after the senior outing : —
Messrs. Reynolds, Shakerley, Cantle, Cocks, Waldon, and Buckley.
Brighton Association of Pharmacy, Thursday, May 13.
— Mr. W. H. Gibson, President, in the chair, supported by the
Hon. Sec., Mr. W. W. Savage. — A meeting of this Association
was held at the Grand Hotel, to discuss the
Proprietary Articles Trade Association.
Mr. Glyn-Jones was present on behalf of the P. A. T. A. — Mr. Glyn-
J ones made a very powerful and telling speech, setting forth the
objects and advantages of the Association, and he urged all
those present who were not members to join, and to do their
utmost to make the movement a success ; by so doing
they would further their own interests and those of
the craft in general. He said that nearly all the wholesale
houses were members, and that it only required the hearty
co-operation of the retail trade to induce the manufacturers and
proprietors to place their articles on the protected list. — Mr. H. A.
Costerton, after a very effective speech, moved the following
resolution
“ That this meeting of chemists residing in Brighton and District cordially
approves of the aims and objects of the P.A.T.A. It pledges itself to support
the Association in every possible way, and urges upon all proprietors the
advisability of adding their preparations to the protected list.”
Mr. Padwick seconded the motion, and suggested that com¬
mercial travellers, who were the feelers of the wholesale trade,
should be made acquainted with the wishes and views of the
chemists at whose places they call, which by that means would reach
the wholesale houses. — Mr. W. W. Savage next spoke, and as
Secretary of the Brighton Association of Pharmacy thanked them
all very cordially for having turned up in such numbers. —
Mr. Martin, of Lewes, also spoke, and made a very vigorous
speech in support of the motion. — Mr. Lynch, of London,
also expressed himself thoroughly in sympathy with all the objects
of the P.A.T.A. — Mr. Aston, Of Worthing, spoke in support
of the motion, but wanted to know how it was that
some firms were still obtaining and selling goods under the fixed
prices.— Mr. Glyn-Jones, in reply, said that he was sorry to say
there were some chemists who sign the agreement and then
hand over the goods to these cutters, but it is possible to trace the
source and stop supplies. He approved of the plan suggested by
Mr. Padwick with regard to commercial travellers, and said he
would be glad to know that no traveller dared come into the
town unless he represented a P.A.T.A. wholesale house. — The
question was then put by the Chairman to the meeting, and it was
carried unanimously with loud applause. — Mr. Williamson next
proposed a resolution : —
“ That the Brighton Association of Pharmacy should he appointed the local
Executive of the P.A.T.A.”
This was seconded by Mr. C. G. Yates. — On the question being
put, it was carried nem. con. — Mr. W. W. Savage then proposed — -
“ That thanks be offered to Mr. Davenport for having included Dr. Collis
Browne’s chlorodyne in the list.”
Mr. J. R. Gwatkin seconded this resolution, which was also
carried unanimously. — Mr. Glyn-Jones next proposed that the
best thanks of the meeting should be given to the Chairman
for the great trouble in organising the meeting, and he urged
all to join the Brighton Association of Pharmacy.— Mr. Blacks
seconded the proposal. — This was carried unanimously amid loud
cheers. — Mr. Gibson returned thanks, and said he was always
pleased to do anything for them, but the credit for the arrange¬
ments of the meeting was due to the Secretaries, Messrs.
W. W. Savage and C. G. Yates, who had both worked
hard. Mr. W. W. Savage proposed a hearty vote of
thanks to Mr. Glyn-Jones, which was heartily accorded,
after which the meeting terminated. — At the close of the
meeting about twenty new members paid their subscriptions
and joined the ranks of the P.A.T.A. — Mr. Savage announced
that the annual outing of the Brighton Association of Pharmacy
will take place in the third week in J uly.
School of Pharmacy Students’ Association. — Friday,
May 14. — Mr. H. E. Matthews in the chair. — A paper by Mr.
A. Miles entitled
A Few Remarks on Electricity
was read in the author’s unavoidable absence, by Mr. W. B.
Nelson. A discussion followed, in which the Chairman, Messrs.
Smith, Morgan, Happold, Smorth waite and the Secretary joined.
Pharmaceutical Chemists’ and Apothecaries’ Assis¬
tants’ Association of Ireland, Tuesday, May 11. — Mr.
William MacCarthy, L.P.S.I., President, in the chair. — The first
annual supper of the Association took place in the Wicklow Hotel.
The evening was an exceedingly pleasant one ; to the right
of the Chairman were Mr. W. F. Wells, President of the
Pharmaceutical Society of Ireland, Mr. Beggs, Treasurer of the
Pharmaceutical Society of Ireland, Mr. Patrick Kelly, M.C.P.S.I.,
and Mr. J. Smith, M.P.S.I., Examiner to the Pharmaceutical
Society of Ireland. To the left of the Chairman were Mr. Jameson
Johnston, M.B., B.Sc., visiting-surgeon, Baggot Street Hospital ;
Dr. Walsh, M.C.P.S.I., proprietor of Messrs. J. J. Graham and
Co.’s State Pharmacy, Dublin ; Mr. W. U. Smith, L.P.S.I., and
May 22, 1897]
PHARMACEUTICAL JOURNAL.
455
Mr. J. C. MacWalter, L.P.S.I. Amongst those present were
J. Tyrie Turner, L.P.S.I. (Hon. Treasurer), D. O’Sullivan, L.P.S.I.
(Hon. Secretary), W. Vincent Johnston, M.P.S.I.,W. J, Dunwoody,
J. Savage, G. G. Fetherston, L.P.S.I., W. J. Hardy, L.P.S.I.
(Vice-President), J. Farquhar, Corcoran, Dewar, Lewis, Taylor,
Nagle, L.P.S.I., etc. — The menu was choice and the wines
excellent. — After supper the Chairman proposed the toast of
“ The Queen,”
and referred at some length to the good accomplished during
Her Majesty’s Reign. As Irish pharmacists they were proud to
meet that night and drink the health of the greatest ruler in the
world. The next toast proposed by the Chairman was
“The Medical Profession.”
Reference was made to the cordial relations which exist between
the doctors and chemists in Dublin, and a tribute of praise paid
to the skill and ability of Irish medical men in general, who
distinguished themselves in all parts of the globe. — Surgeon John¬
ston returned thanks. As an old pharmacist, prior to his entering
the sister profession, he had had many opportunities of studying
the secret of the existing good-fellowship between the followers of
pharmacy and medicine. Happily in Dublin there was an almost
total absence of the compounding doctor and the prescribing
chemist. The medical profession owed a debt of gratitude to the
Pharmaceutical Society, whose licentiates might be fairly regarded
as the hand-maidens of the medical faculty. Like charity, they
covered a multitude of sins, and doctors had often good reason to
be grateful for the help afforded to them by the pharmaceutical
craft. He referred to the rapid growth of the junior association,
and was glad to see that the scientific element had a large share
of the syllabus for the past session. Up to very recently too
much attention had been paid by the chemist to the art of making
money, and he rejoiced to see that this was changing in favour of
a higher object, namely, the elevation of pharmacy into an
acknowledged profession, and he hoped to see this consummation
at no distant date. — Dr. Walsh also spoke. A pharmacist for
some years, he had the old love of the craft strong within him, and
although he had entered the portals of medicine, he felt as much
of a pharmacist as ever. He paid a high tribute to the way in
which the pharmacists of Dublin carried out the work entrusted
to them by the physicians, complimented the Association on its
prosperous condition, and felt sure that the social meeting that
night would still further strengthen the existing goodwill between
the physician and the pharmacist. He urged the junior members
to study the scientific side of therapeutics, and do all in their
power to make themselves worthy of the trust reposed in them by
the doctors and the public. — Mr. W. J. Hardy, L.P.S.I. (Vice-
President), proposed the toast of
“The Pharmaceutical Society of Ireland,”
coupled with the names of the respected President, Mr. W. F.
Wells ; the Honorary Treasurer, Mr. Beggs ; and Councillor Patrick
Kelly. The Junior Association of pharmacists in Dublin owed a
lot to the parent Society, and they would indeed be wanting in
gratitude if they failed to take the present opportunity of thanking
the Council for so generously placing the Society’s rooms in Lower
Mount Street at the disposal of the Association. The licentiates
throughout Ireland could have no more worthy representatives on
the Council than the gentlemen whose names were coupled with
the toast. Mr. Wells did not spare himself to befriend the young
men in the pharmaceutical profession, and it was largely due to
his and his fellow-Councillors’ personal influence that the licentiates
of the Irish Pharmaceutical Society occupied their present position
in the social and professional world. While they had Mr. Wells
at the head of affairs there need be no fear for the future. — Mr.
Wells, whose rising was the signal for continued applause, thanked
the Association most heartily for the very kind way in which the
toast had been received. He felt that in coming to the enter¬
tainment he was coming amongst sincere friends. The interests
of the Society and Association were identical. The Council
had always the desire to do all they could for the
benefit of the licentiates. The Council had a great many
things to contend against which did not appear on
the surface, but he could assure them that everything was done
for the good of all classes and conditions of pharmacists. Since
the Pharmaceutical Society was formed twenty-two years ago it
had been his great aim and object to raise the standard of
pharmacy, and he flattered himself that his efforts had not been
unsuccessful. When the Society started, pharmacy was at a very
low ebb, indeed, most of the compounding throughout the country
was done by apothecaries, and there was consequently a great
want of qualified chemists to meet the growing demands of the
public. The Pharmaceutical Society, as they were probably
aware, had its birth owing to the refusal of the Apothecaries’
Hall to recognise pharmaceutical requirements, and thanks to the
energy of some good men from Belfast and others the Pharmacy
Act of 1875 soon became a power for good. He was not ashamed
of the work done during the past two decades. During
the last seven or eight years pharmacy had made great
strides. Englishmen and Scotchmen had joined their ranks, and
the number was steadily increasing. The Society wanted all the
recruits possible. Some, he was sorry to say, had entered the
profession with no higher object in view than to make the most
money they could out of it. The true pharmacist should aspire to
something nobler than mere money-getting. It was necessary for
them to put their shoulder to the pharmaceutical wheel and give
it a strong push along the road of progress. He hoped that the
Association would hold many more successful meetings in the
Society’s House in Mount Street, and looked forward to many a
pleasant and instructive evening there. His sympathies, and
those of the Council, were with the Association, and on behalf of
his absent fellow-Councillors he thanked the Association for the
very kind reception given to him. — Mr. Beg os also returned
thanks in felicitous terms. He thought that if there was a little
more of the social element than there had been in the past, it
would be better for all. He considered that the line of demarcation
between employers and their assistants had hitherto been too closely
drawn. He re-echoed the President’s good wishes for the success
of the Association, which had a firm friend in him. Mr. Beggs’
pledge of friendship was received with loud applause. — Councillor
Kelly, in the course of a speech interspersed with pleasing anec¬
dotes, corroborated the two last speakers. The Association was
no longer the little boy in knickerbockers, but was now wearing
the long trousers of maturity. He referred in humorous terms bo
the study of bacteriology and the isolation of microbes. At present
the matrimonial microbe was strongly in evidence in pharmacy, and
he was happy to say that not all the scientific meetings held by
the Association could eradicate that particular germ. The toast of
“Our Visitors”
was next honoured. — Mr. Wells (President of the Pharmaceutical
Society of Ireland) proposed the toast of “ The Association, its Presi¬
dent, and V ice-President. ” That the Association studied the social as
well as the scientific side of pharmacy was evidenced by the hospi¬
tality shown to himself and his colleagues of the Council. The
Association had done well in the past, but it should do better in
the future. No man was worth his salt if he did not improve with
age, and the same thing applied to the Association. Upon the
President and Vice-President depended much. If there were not
good men at the helm the ship was in danger of going ashore ; but
however good they might be, they could do little without a good
crew. — The Chairman (Mr. W. McCarthy, L.P.S.I.) responded to
the toast, and said a great deal of the success of the Association
was due to the kindness of the Pharmaceutical Council and the
medical profession. He hoped that the next session would eclipse
all others, and that they would have the pleasure of welcoming
the Council to their scientific and social meetings very soon. The
policy of the Association was broad in the extreme. — Mr. Hardy
(Vice-President), in an effective speech, traced the origin and
growth, of the Association up to the present. — The health of the
Honorary Secretary, Mr. David O’Sullivan, L.P.S.I., and the
Honorary Treasurer, Mr. J. Tyrie Turner, L.P.S.I., were honoured.
During the evening songs, duets, and recitations were contributed
by Dr. Walsh, Mr. W. F. Wells, Mr. Taylor, Mr. Fetherston, Mr. *
Farquhar, Mr. Dewar, and others. Mr. Lewis presided at the
piano with his customary ability. The company separated in
good time to the refrain of “ Auld Lang Syne,” and the echo “ To
our next Merry Meeting.”
Proprietary Articles Trade Association, Thursday,
May 13. — At a meeting of the Liverpool members the following
local secretaries for the P.A.T.A. were appointed
Local Secretary for Liverpool
T. S. Wokes, Grassendale.
Assistant Local Secretaries : —
Wm. Gabites, 51, Upper Warwick Street, Liverpool.
T. Hamnett, 38, South Road, Waterloo.
Joshua Hocken, 31, Old Hall Street, Liverpool.
456
PHARMACEUTICAL JOURNAL.
[May 22, 1897
Thos. H. Hudson, 111, Prescot Road, Fairfield.
W. F. Partridge, 97, Admiral Street, Liverpool.
J. Smith, 164, Aigburth Road, Toxteth Park.
R. Stock dale, Blundell Sands Road, W., Gt. Crosby.
Photographic Section : — -
F. Y. A. Lloyd, 5, South John Street, Liverpool.
Important steps were decided upon, relating to carrying out the
details of the P.A.T.A. at Liverpool. Some discussion took place
with regard to the attitude towards the movement taken up by
Messrs. Evans, Sons and Co., of that city, and the following reso¬
lution was unanimously passed : —
“ That this meeting of the Liverpool members of the P.A.T.A., recognising the
friendly attitude of Messrs. Evans, Sons and Co., and remembering their
communication 1 that they would act in accordance with the wishes of their
retail friends,’ desire to express their regret that Messrs. Evans, Sons and Co.
have not yet given their support to the P.A.T.A., and to hope that they will
see their way to do this.”
Mr. R. C. Cowley was heartily thanked for his kindness in
allowing the meeting to take place at the Liverpool School of
Pharmacy.
IVIEETIJ1GS Of SCIEfJTIfIG SOCIETIES
- ♦ -
Royal Institution, Thursday, May 13. — The last of the
course of lectures on —
Liquid Air as an Agent of Research,
was delivered by Professor Dewar, who commenced the lecture by
dealing with the limiting volume of substances at the zero of
absolute temperature. It wras impossible, he said, to believe that
matter at that temperature would have no mass, and the extension
by extrapolation of the curves expressing variations of density at
attainable temperatures might give entirely wrong results, because
at low temperatures many properties of bodies dropped, as it were,
over a precipice. Professor Dewar then illustrated by experiments
the changes produced in the elastic constants of various substances
by intense cold, and proceeded to discuss chemical action at low tem¬
peratures. All ordinary reactions entirely ceased, chiefly because
everything became solid — a stateof matter not favourable to chemical
action. Photographic action, however, persisted to a certain extent,
particularly if gelatin plates were used. That might probably be
explained as indirectly due to the property possessed by organic
bodies, especially the more complex ones, of phosphorescing at
low temperatures. The lecturer also showed how cold increases
the magnetic moment of a permanent magnet by as much as 20 or
30 per cent., and by a number of experiments illustrated the mag¬
netic properties of liquid air itself. He then referred to the effects
of extreme cold upon living organisms. In the case of ordinary
putrescent matter it was found that the spores were not killed by
being subjected to the temperature of liquid air, and experiments
were now being carried out to discover whether seeds exposed to
liquid air for at least one hundred hours still retained the power of
germination.
Linnean Society of London, Thursday, May 6. — Dr. A.
Gunther, F.R.S., President, in the chair. — Professor Ludwig
Radlkofer, of Munich, was elected a Foreign Member. — In view of
the approaching anniversary meeting, Mr. Osbert Salvin and
Professor Farmer were elected Auditors on behalf of the Council,
and Messrs. E. M. Holmes and H. Druce on behalf of the
Fellows. — Professor Stewart, F.R.S., then exhibited and made
remarks on some anatomical preparations showing the different
modes of
Attachment of the Ligamentum nucha:,
in herbivorous and carnivorous mammals, as exemplified in the
sheep and dog, and of the Ligamenta subflava. The analogous
ligaments of birds were dealt with, and special attention was drawn
to a preparation of the vertebral column of the python, showing
vertebra-costal fibro-cartilaginous plates of which he could find no
description, and which he believed to be peculiar to the Ophidia. —
The Secretary read the abstract of a paper by Messrs. W. and
G. S. West
On Desmids from Singapore.
These had been discovered in a small collection of algae forwarded
by Mr. H. N. Ridley, F.L.S., from Singapore, and, in addition to |
seven species previously known from Sumatra, contained several
which were new, and now described and figured. — Professor
Newton, F.R.S., communicated a paper by Captain F. W.
Hutton, Curator of the Canterbury Museum, Christchurch, N.Z.,
entitled — •
The Problem of Utility,
in which the views of Dr. A. R. Wallace on “ The Utility of
Specific Characters” ( Journ . Linn. Soc., Zool., xxv., pp. 481-496)
were criticised, chiefly as tested by the study of the fruit-pigeons
( Ptilopus ). — The Secretary gave an account of a paper by the
Rev. R. Boog Watson, LL.D., “ On some new species of Mollusca
from the Island of Madeira,” prefacing his remarks with a brief
resume of the researches previously made in the same direction by
Messrs. Lowe, Wollaston, and other conchologists.
Royal Society, Wednesday, May 19. — A conversazione was
given by the Royal Society, when the visitors present were enter¬
tained by a display of many scientific objects of recent interest.
Almost every branch of science was represented, theoretical sub¬
jects and practical apparatus both being plentiful. Probably no
discovery will excite more popular interest than photography in
colours. The most striking results hitherto obtained in this direc¬
tion have been made by the Dansac-Chassagne process. It will be
remembered that this method involves the treatment of the
ordinary silver print successively with blue, green, and red
colouring materials, in such a way that the colours
automatically unite to form the proper tints in their
correct position on the picture. A number of colour photo¬
graphs, both landscape and portrait, taken by this process were
shown by Sir H. Trueman Wood. The successive stages in the
development of the photos were well illustrated. A photo contain¬
ing a bouquet of flowers reproduced their natural colours very
beautifully. The exhibit of physical apparatus was extensive.
J. Wimhurst exhibited an electric influence machine having
twenty-four discs, each three feet in diameter. It is arranged to
give three poles, one being positive, while the other two are
negative, or vice versd. Thus the streams of discharge
can be used simultaneously. This machine is capable of
giving a very high potential ; a spark passes between the
terminals thirty-four inches apart, while if discharged over
metal-faced paper the spark reaches a length of twelve feet. Sir
A. Noble had an apparatus for comparing the value of explosives.
It registers in the form of a curve the pressure generated by
explosion and the rate at which the pressure decreases by cooling.
A pretty experiment by J. W. Swan showed graphically the stress
produced by convective electric discharge. When a viscous mix¬
ture of resin and oil is interposed between the terminals, the
surface of the fluid is thrown into a series of ridges and depressions.
If a plate of solid resin be interposed for a time, the same effects
are developed by subsequent warming to soften. The walls of the
room were hung with diagrams showing the results of the
Rothamsted experiments in agriculture. The bones of the exti net
Naquada race recently discovered in Egypt were shown and their
features pointed out. A series of astronomical spectra was
exhibited by J. Norman Lockyer, illustrating the importance of
particular lines in the hottest stars. Many lines previously
classed as unknown are shown to be enhanced lines of known
elements.
Test for Nitrites in Water. — The following substitute
for the metaphenylene-diamine reaction for nitrites in drinking
waters is advocated by Barbet and Jandrier. Two cubic
centimetres of the water are taken, and 10 centigrammes
of resorcin dissolved therein. To the solution 1 C.c. of pure sul¬
phuric acid is cautiously added, being allowed to trickle down the
side of the tube so as to avoid an immediate mixture. The tube is
gently agitated so as not to unduly raise the temperature. After
the lapse of an hour the rose colour developed, if nitrites are
present, is matched with that produced by a solution of a nitrite of
known strength. Water containing one-tenth part per million of
sodium nitrite gives a very characteristic tint in a few hours. In
place of the standard nitrite solution a colorimetric scale may be
made by means of dilutions of solutions of cobalt chloride in water.
— Journ. de Pharm. [6], iv., 249.
May 22, 1897]
PHARMACEUTICAL JOURNAL.
45 7
LEGAL INTELLIGENCE.
PROCEEDINGS UNDER THE PHARMACY ACTS.
Cases at Glasgow.
Two cases came before Sheriff Fyfe at the Sheriff Court House,
Glasgow, on Monday, May 17, at the instance of Mr. Richard
Bremridge, Registrar under the Pharmacy Acts, 1852 and 1868.
Mr. Barrie, writer, Glasgow, instructed by Mr. P. Morison,
S.S.C., Edinburgh, appeared for the prosecutor, and Mr. Gemmel,
writer, Glasgow, appeared for the defenders.
The first case was against Minnie Peatt, assistant to Dr. Mac¬
donald, 282, Cumberland Street, Glasgow, who was charged with
selling laudanum on November 21, 1896, to an agent of the
Registrar.
Defender pleaded not guilty, and by request of the Sheriff, Mr.
Gemmel conducted the defence.
Mr. Rutherford Hill proved that defender was not registered,
and that the article sold was laudanum. There had been great
difficulty in getting the name of accused, which she persistently
refused to give. The name of Minnie Beattie had been got and a
complaint served on the defender in that name, but it was with¬
drawn when the correct name was got.
The witnesses Spence and Tait proved the purchase of the
laudanum from accused, who was alone in the shop.
Eor the defence, accused said in reply to the Sheriff that she was
an assistant in the shop, which belonged to Dr. Macdonald. She
had no recollection of selling laudanum to Spence, but she remem¬
bered selling him a seidlitz powder. She could not say whether
the doctor was in. She was the only assistant in the shop.
Examined by Mr. Barrie, she said the doctor had no particular
consulting hours. She did not know why the address, 10, Adelphi
Street, was on the label. Dr. Macdonald had no shop there.
These were the labels used at 282, Cumberland Street. She had
been two years in the shop. She thought Dr. Macdonald would
be there on November 21 at 7.30 p.m. She took the complaint
against Minnie Beattie from the Sheriff’s officer, and she asked him
to take it away, but he would not do so. She did not say to the
officer that her name was Beattie. She refused to give her name
to Spence. He did not say what he wanted it for.
The Sheriff : Then I think you were quite right to refuse.
Witness: When she came out of the shop at night Spence was
outside and followed her home, and she was afraid to pass through
the Green.
Mr. Spence, recalled by the Sheriff, said the accused several times
refused to give her name. He was instructed to find out where
she lived, and as no one could give him the information he took
that plan.
The Sheriff : Did you think that right ?
Mr. Spence : I was instructed to do so. I told her I would say
why I wanted her name if she would give it to me.
Mr. Gemmel said it was high time the Courts should mark its
disapprobation of the manner in which the Society conducted
these cases and the means they adopted for getting information.
He submitted that in this case only a nominal penalty should
be imposed and without expenses.
Mr. Barrie said there was no reason why in this case the same
penalty should not be imposed as had been imposed in previous
cases of a similar kind. This person had refused to give a name,
and her mother had also refused it, and she told the Sheriff’s
officer her name was Beattie, but not Minnie Beattie. It might
be the Society could adopt some other means to get names, but it
had to be remembered that the agents of the Registrar were in a
very different position to the inspectors under the Sanitary Acts,
where they could demand a sale. They had no power either to
compel offenders to give their names. They were also precluded
from saying they had come from the Society, because it had been
found that these parties, who knew quite well they were breaking
the law, telephoned to all the shops in the neighbourhood if they
found out that -the Society’s officers were in the district. The
inquiry which the Society had to conduct was thereby frustrated.
The Sheriff said it might be quite true that the Society had to
get the evidence in these cases without the seller knowing any¬
thing about it. But there did not seem any reason why when the
purchase had been made they should not there and then tell the
purpose for which it had been purchased. The offenders would
not then have the difficulty they had of trying to remember what
happened at such a distance of time. It might be that these
inspectors had not the same powers as under other Acts, but
he thought there should be no difficulty in getting such powers,
and he was surprised that a powerful society like this did not
apply itself to the getting of some remedial legislation which
would bring their procedure more into accordance with fair-play.
In this particular case he must express his strong sense of dis¬
approbation of the mode employed by the inspector in getting this
girl’s name. If he had asked it at the time, and told that he
wanted it because there was to be a prosecution and got a refusal
it would have been very different. But to ask it without any
reason, and after a lapse of time, and to pester her in such a way
did not reflect credit on an officer of the Society, and in his view
any young lady was justified, and her mother also, in refusing the
name to a stranger. Such inquiries must be conducted on fair
lines. Though he must find that technically an offence had been
committed, he would mark his disapprobation of the methods
adopted to get information by imposing a nominal penalty of half-
a-crown, and he would allow no costs.
The next case was against Alexander Wilson Hendry, assistant
to Dr. Dunning, 383, Cumberland Street, Glasgow, who was
charged with selling laudanum and Powell’s balsam of aniseed to
two agents of the Registrar on November 21, 1896.
Defender pleaded guilty.
Mr. Gemmel said defender had no recollection whatever of what
happened on the date mentioned. He drew attention to the
case dismissed by Judge French on the ground that one month
had elapsed between the offence and the raising of the case, and
said that in the present case there was an interval of five months.
This was a case quite of the same kind as the one just disposed of.
The Sheriff : No, I think this is the exact converse of the case
I have j ust heard.
Mr. Barrie said this was another of Dr. Dunning’s assistants.
The other assistant was convicted on last Court day, and his Lord-
ship would remember how in that case it was shown that the
respondent refused to disclose his real name. He had told
Mr. Gemmel that the prosecutor would drop the original
complaint and bring a fresh one if he would give his real
name, but it was refused. It was earnestly to be hoped that these
unqualified assistants would particularly note what had been said
as to furnishing their names on demand to the agent of the
Registrar. Hitherto the Society had been met by nothing but ob¬
struction in trying to get these names. He thought this was not a
case in which any mitigation of penalty should be made.
The Sheriff said he had a distinct recollection of what trans¬
pired on last Court day, and he was then convinced that the
defender had treated the prosecutor with a great want of frank¬
ness. There could be no doubt that defender knew quite well that
the officers wanted the information for the Registrar, and he ought
to have been quite frank. He did not think it was quite fair to
endeavour to trap parties into the commission of offences ; but, on
the other hand, these young men must be perfectly fair and frank.
Theymust know that theseproceedings were in the public interest, so
that persons who required drugs should be protected against harm
and loss. He could not take it from any assistant that he was not
quite well aware that he could not legally act in this way. These
cases were rightly taken in the public interest, and he could not
take the view that there was any mitigating circumstance in this
case, except the usual one in these cases — namely, that while the
defender was the hand by which the sale was made, and therefore
liable, he was only the doctor’s assistant, and the doctor was far
more the offender than he was. He would for that reason impose
the usual modified penalty of 5s. for each offence and £2 of costs.
Sodium Bicarbonate as a Dressing. — In the Sem. MM.,
March 3, Georgevsky states that a compress saturated with a
solution of chemically-pure bicarbonate of sodium, and covered
with some impermeable material, will dry up purulent secretion
and cut short phlegmonous inflammation. Results are obtained
by this method far more rapidly than any other means. After
penetrating the epidermis, the integument should be softened by
applying compresses of tarlatan soaked in a 2 per cent, solution of
bicarbonate of sodium. In several cases under Georgevsky’s
notice this treatment effected a rapid cure without the necessity
for using drainage. Whenever iodoform was substituted for bicar¬
bonate of sodium, suppuration began anew, ceasing again when the
bicarbonate was reapplied. — Brit. Med. Joum., Epit., i., 1/97/51.
458
PHARMACEUTICAL JOURNAL.
[May 22 1897
LEGAL HINTS FOR PHARMACISTS.
Medicine Stamp Acts.
(Continued from page 354.)
Proprietary Right.— The words of the Statute establishing
the charge under this heading are “ hath'^r claims to have any
exclusive right in or title to the making or the preparing of the
same,” the concluding word having reference, of course, to the
articles mentioned in the Schedule to 52 Geo. III., cap. 150, and to
the statutory expansion of that Schedule effected by the clause
“all other pills, powders, lozenges, tinctures, potions, cordials,
electuaries, plaisters, unguents, salves, ointments, drops, lotions,
oils, spirits, medicated herbs and waters,” etc., intended for use as
medicines or medicaments for human beings. If one spoke
unreservedly it might be asserted that no registered chemist
who confined himself to the legitimate practice of pharmacy need
be hit under this Section of the Act. Perhaps, however
“ legitimate pharmacy,” like the “ legitimate drama,” may be provo¬
cative of considerable dissension, but, seeing that pharmacy has so
often been referred to as the handmaiden of medicine, the use of
the qualifying word in connection therewith ought not to
be open to very much ambiguity. The proprietorship to
which chemists have the highest claim is that of
competent technical skill and scientific knowledge in pre¬
paring, compounding, and dispensing the medicines prescribed by
medical practitioners, and the remedies mentioned in the national
Pharmacopoeia. That right may be made known to the public, if
one possesses the title, without involving any liability to a duty
which was chiefly intended to fall upon quacks and their nostrums.
Happily or unhappily, according to the view one chooses to
take, there are inherent commercial instincts in the heart of man
— even in the heart of the professional man ; and Smith the
chemist, regarding the success of Brown the grocer in selling
“ Brown’s celebrated Hygienic Hyson,” feels impelled to invite
the public to accord a similar patronage to “ Smith’s World-famed
Indigestion Cure.” And Smith becomes from that hour an object
of solicitude to the Revenue authorities. Whether he at the same
time lowers the dignity of his calling it is not our business to
discuss just now.
The outward and visible sign of a claim to have a proprietary right
in a medicine is the use, by way of prefix, of a proper name in the pos¬
sessive case. That is an obvious and natural way of conveying the
idea of ownership, and, as Alpe in his valuable ‘Handy Book’ has
pointed out, it is the view which has frequently been acted upon in
the Courts. There are some notable exceptions in which the use of
the possessive case involves no claim to proprietorship in the
medicine, but we propose to deal with these later on when discus¬
sing the exemptions authorised by statute or allowed in practice.
The claim to exclusive right in any preparation may be true or
false without in any wise affecting the liability to duty. “ Mrs.
Harris’ Cordial ” would be liable, though Mrs. Harris may never
have had corporeal existence. The vendor is frequently not the
proprietor of a medicine in the truly legal sense of the word, but
the Stamp Act does not trouble about such nice distinctions, and
if A acquires B’s business and uses B’s name in a proprietary con¬
nection, A must take out a licence and stamp the dutiable articles.
It may also be mentioned at this point that any preparation which
has been sold as a stamped medicine cannot afterwards be removed
from liability to duty. That is to say, if A on coming into B’s
business thought it desirable to sell certain preparations which
B had sold as stamped medicines, A could not claim exemption
from duty, though he personally might use innocent labels and do
none of the acts specified in the Statute as bringing a preparation
into the net of chargeability. Naturally it might be difficult for
the authorities to detect evasions arising in circumstances
similar to the above supposititious change of business pro¬
prietors, more especially if B’s specifics had not attained any
marked reputation, but it must always be remembered that the
burden of proving that any particular article is not chargeable
with duty rests upon the defendant — a somewhat uncomfortable
burden at times.
Again, there are more ways than one of urging proprietary right,
whether real or assumed. The label may bear the words “ Made
only by X,” or “None other genuine,” or “Observe the trade mark,”
in, which cases the proper name of the vendor or maker might be
in any declension without altering the chargeability of the article. This
may be called the “ claim indirect,” in contradistinction to the clai n
direct, conveyed by the use of the possessive case. The claims
may, however, be more indirect still. The labi 1 may in itself be
non-liable, but the energetic vendor may exhibit in his shop window
a notice calling attention to his (in the possessive) blood mixture,
and that notice will be sufficient to render liable all the blood
mixtures in his shop. Cases might be quoted to sustain this
assertion, but it may be sufficient to simply impress the moral that
non-liable labels do not necessarily imply that the articles they cover
are also free from liability. In the absence of a window notice, a
price-list or catalogue, or even an advertisement in a newspaper,
may often bring about the same unsuspected and undesired
liability ; and it will be no defence to say that the statements
made to the public are untrue, or that the blood mixture is
nothing more than a simple mixture, the composition of which was
probably public property centuries back. For the purposes of
Inland Revenue, Somerset House places a childlike faith in
your public announcements, and acts accordingly. Such ex¬
pressions as “J. S. desires to call attention to the following list of
valuable- remedies specially prepared by him ” should therefore be
avoided in price-lists, almanacs, and similar trade stimulants. It may
be noted that no liability actually ensues from verbal statements
made by a medicine vendor in respect of a medicine he sells. That is
to say, anon-dutiable article does not become chargeable by reason of
the vendor saying to the purchaser, “You cannot get that any¬
where else in this country, I make it according to a special
formula of my own.” Strictly speaking of course the claim is
there, but it would be extremely risky to make oral statements
such as pass between vendor and customer the ground for
prosecution.
THE PHARMACIST AS A PHOTOGRAPHIC DEALER.
BY A PHARMACIST AND PHOTOGRAPHER.
In the early days of photography, the amateur photographer
was by no means so common as at the present time, and the call
for photographic dealers but small. With the introduction of
gelatin dry plates, however, photography at once took a leading
position as a hobby, and when the professional photographer had
the chance to take up the position of dealer and the friend of
amateurs, the class to which he belonged looked upon the man who
followed their craft as a hobby as their natural enemy, the man who
was to take away their bread and butter by working for nothing, or
at practically prime cost. This then was the chance for the
pharmacist to take up the neglected role , and some availed them¬
selves of it. With the passing of the years the number of amateurs
has not decreased, in fact one would not be far wrong in saying
that they have considerably increased in numbers, and to supply
their wants is an adjunct to the ordinary business of pharmacy
which will be found to pay better than selling “patents” at cut rates.
It must not be supposed, however, that cutting is unknown in
the photographic world, many large dealers cutting the prices of
well-known articles such as pyrogallic acid, doubtless in the hopes
of securing customers for the more paying and more expensive
goods. The cutting of plates and sensitive papers has, however,
been stopped to some extent by the formation of an association,
which has been joined by practically all the leading plate and
paper makers, with the result that the dealer now gets his full
discount and full profit, or if he tries to cut, cannot obtain the
goods. '%
Photography being a pastime founded principally on the art of
chemistry, it seems Dut fitting that the pharmacist should cater
for the wants of its devotees. It is not actually essential that the
dealer should himself be a photographer, though this undoubtedly
gives him an advantage in that he can assist chance customers by
advice, and thus gain firm hold of them. Though it must not be
forgotten that the amateur photographer, particularly the
beginner, is an insatiable animal, who seems capable of absorbing
any amount of advice gratis without spending much money, but it
is unnecessary to give any advice upon this point, for the bore
may always be got rid of.
The necessary outlay of capital when setting up as a photo¬
graphic dealer need not be heavy, as the stock may be increased
from time to time and added to as the requirements are found out.
May 22, 1897]
PHARMACEUTICAL JOURNAL.
459
As regards cameras, the humble quarter- plate or very popular half-
plate will be found the sizes most in demand, and whilst many
camera manufacturers advertise largely in the photographic press,
and thus create a demand for their wares, it is, we think, preferable
to obtain a particular make of camera by a less-known maker and
push it as one’s own. In such a case it is as well to know all the
weak points of the well-advertised cameras and the strong ones of
your own, so that a comparison in the favour of the latter may be
drawn.
With regard to lenses, it may be assumed that as a rule the more
intelligent amateur and the more advanced worker will only pur¬
chase well-known makes of lenses, but as really good foreign, prin¬
cipally French, lenses can be obtained at prices from one-fourth to
one-half of those bearing the name of eminent opticians, it would
be as well to stock one or two. It is also advisable, if the business
is to be gone into thoroughly, to make one or two negatives and
prints with the lenses and cameras, and thus show their capabili¬
ties, because such results carry far more weight than any amount
of talking.
Coming now to dry plates, the advice may be given to feel the way
very cautiously and to stock only those plates which are asked for.
Should a chance customer come in for a brand of plate or parti¬
cular kind of paper which you do not have in stock then try and
ascertain how much the customer is likely to use, and then tell
him you will keep the goods in stock for him. As regards the
minor apparatus, such as printing frames, measures, dishes, etc. ,
there is not much trouble, nor do they require any very great
outlay, because it will be rarely necessary to go beyond the whole
plate size.
Considerable experience has shown that where the average
pharmacist fails as a photographic dealer is in his ignorance
of the business in the minor details. It is of course very rare
that one comes across a man who is thoroughly au fait with every
branch and every piece of apparatus, but the dealer should
at least know where to go to get everything. The best
advice that can be given to the pharmacist who wishes to cultivate
the photographic trade is first of all to obtain catalogues from the
leading houses, such as Fallowfield, 146, Charing Cross Road ;
Adams and Co. , Aldersgate Street ; Marion and Co. , Soho Square ;
Levi and Co. , Hatton Garden ; and S. J. Levi, Farringdon Road ; also
the British Journal Almanac, which is in itself a collection of price¬
lists. All these should be studied and carefully noted as to prices, etc.
The photographic press, too, should not be neglected. There is
not much to be gained by selling the weekly newspapers, but
some at least should be kept, as well as a bookslide of the best
selling photographic hand-books, etc. , and whilst it will not pay
to go direct to the publishers, as a rule at least, Messrs. Dawbarn
and Ward, of 6, Farringdon Avenue, will supply all papers and
books on terms quite as low as can be obtained for small quantities
from the publishers themselves. If the weekly papers are taken, one
or two of them should be glanced through to see whether anything
special is stirring ; whether as is often the case, any new
chemical is just coming to the front. If so, it should be noted,
and if not obtained, one should at least find out whence
it can be got in case it is wanted. As a proof of this it
may be stated that only within the last few months a case
has been brought under notice of a demand arising for potassium
ferric oxalate, and a chemist having been asked for it stated
that there was no such salt, as he could not find it in his wholesale
price-list. As a matter of fact there are many chemicals used in
photography which find absolutely no place in the B.P., the ‘ Extra
Pharmacopoeia,’ Squire’s ‘Companion,’ or Attfield’s ‘Manual,’ and
yet they are well known to photographic dealers. As a rule, of
course, such things may be obtained by ordering specially from the
ordinary wholesale druggists or from Messrs. Hopkin and
Williams, or Mawson and Swan, of Soho Square, the latter making
a specialty of photographic chemicals.
One of the most lucrative branches of the business is in the
selling of ready-made solutions. The average amateur is, as a
rule, a bit clumsy with his scales and chary of making up his own
solutions if he can get them ready made at reasonable prices, but
at the same time he is decidedly unwilling to buy a “pig in a poke,”
and if he wants, let us say a toning bath, he likes to know exactly
how much gold it contains. In this department it is always advis¬
able to take standard formula; and make them up and label them,
and it will be found that many will be willing to pay just a little
more if they can get their solutions properly made up, and there is
also, of course, the profit on the raw material itself. _______ t _
There is possibly one caution which, speaking from an experience
of many years, both from the amateur point of view and that of
the dealer too, will not be out of place. When asked for a chemical
be quite sure that you know what is meant, and do not be in too
much of a hurry to correct your customer. As examples may be
cited two cases recently brought under notice, which are not
solitary instances. An amateur entering a big chemist’s shop not
a hundred miles from 17, Bloomsbury Square, asked for
a pound of carbonate of soda, and the assistant gravely
supplied him with sodium bicarbonate. Of course in the ordinary
way this was a perfectly legitimate action, but in this instance the
substance was by no means what was required. The second
case was when an ounce of mercuric chloride was asked for,
and calomel supplied, and the assistant was somewhat sur¬
prised when told that it was not what was wanted: “Not
the mercurous, but the mercuric chloride.” The amateur photo¬
grapher who reads his papers and hand-books knows as a rule
far more of the chemistry of photography and photographic
chemicals than the average pharmacist, and therefore a mistake
should be carefully guarded against.
Speaking from personal experience, it may be said that a photo¬
graphic connection is not difficult to work up. It certainly pays
for the trouble, and is, taking it on the whole, far more profitable
than the “ patent” medicine, the packet tea, or the cigar trade, and
can hardly be said to lower the status, either professional or social,
of the chemist. By all means fit up, if possible, a dark-room for
customers’ use, and write to all the photographic papers, as well
as to the Pharmaceutical Journal, informing them of the fact, so
that they may give you free advertisement, and you may thus
catch stray visitors as customers, especially in the holiday season.
In succeeding papers it is proposed to deal with the preparation
of developers, etc., which may be put up for sale, and also some of
the less known wholesale houses whence goods may be obtained.
OBITUARY.
Hemingway. — On April 14, at Storrington, Walter Hemingway.
Aged 79. Mr. Hemingway was formerly on the Register of Phar¬
maceutical Chemists and a member of the Pharmaceutical Society,
at which time he was interested in the firm of Messrs. Alexander
and Walter Hemingway, of Portman Street. This firm obtained
a prize medal at the Great Exhibition of 1851 for ammonio-citrate
of iron and citrate of quinine and iron, and Mr. Hemingway read
an excellent paper on those preparations before one of the medical
societies. While resident at Storrington he started, and for a
time managed, a successful cottage garden show, he also con¬
ducted a night school, and owing to his persistent efforts the
Small Holdings Act was put into operation there.
Barber. — On April 26, George Barber, Pharmaceutical Chemist,
West Kirby, Birkenhead. Aged 71. Mr. Barber had been a
Member of the Pharmaceutical Society since 1853.
Sttxrges. — On April 30, William Thomas Sturges, Chemist and
Druggist, London. Aged 61.
Ford.— On May 4, Joseph Ford, Chemist and Druggist, London.
Aged 79.
Walters.— On May 5, John Walters, Chemist and Druggist
(Mod. ) late of Brecon. Aged 50.
Willson. — On May 14, Stephen John Willson, Chemist and
Druggist, Peterborough. Aged 61. Mr. Willson died somewhat
suddenly at his residence, Norwood House, Park Road. He had
been in business in Peterborough for 33 years, and had gained
general confidence and esteem by his uprightness, consistency, and
kindness.
Hodder.— On May 12, Henry Hodder, Pharmaceutical Chemist,
Bristol. Aged 78. Mr. Hodder had been a member of the Phar¬
maceutical Society since 1847.
Stearn. — On May 14, Ralph Marmaduke Stearn, Pharmaceu¬
tical Chemist, London. Aged 24. Mr. Steam’s death occurred
quite unexpectedly, and came as a severe shock to all who were
acquainted with him. He passed the Minor in April, 1896, and
the Major in April of the pr( sent year. At the last meeting of the
Council Mr. Stearn was accorded permission to work in the
Pharmaceutical Research Laboratory.
460
PHARMACEUTICAL JOURNAL.
[May 2?, 1897
NOTES AND FORMULAE.
( Specially compiled for the Pharmaceutical J oumal. )
Essences of Soaf.
White Castile soap, 100 parts; alcohol, 80 per cent., 200 parts ;
pure carbonate of potash, 12 parts. The soap is dissolved in a wide-
mouth bottle on the water bath by constant shaking with the
alcohol, the carbonate of potash is then added. Then tint with
saffron, or rosaniline and perfume. Leave for some days in the
cold, and filter. An excellent perfume for the above is obtained by
mixing tincture of vanilla, 10 ; tincture of orris, 20 ; extract of
rose, 20 ; extract of orange flowers, 50 parts. Rodiquet recom¬
mends for the preparation of the essence : white soap, 1 ; alcohol,
85°, 3 ; distilled water, 1 , and for medicinal purposes the follow¬
ing mixture, which lathers strongly in water : white Castile
soap, 20 ; distilled water, 30 ; 60° alcohol, 60 ; potash, 1, and 1 per
cent, of perfume. j — Zeit. d. AUg. (Est. Apoth. Verein, x., 31.
Paraffin-Naphthalin Emulsion as a Plant Insecticide.
One part of naphthalin is dissolved by heat in 10 parts of
paraffin oil. The solution is well shaken with a solution of 33
parts of soft soap in 33 parts of water at about 85° C. The
emulsion thus obtained is very permanent, and 15 parts of same
diluted with 1000 parts of water gives a very effective solution for
destroying insects. — Pharm. Gentralh., xxxviii., 242.
Pure Oxalic Acid.
To obtain pure oxalic acid Riechelmann recommends the recrystal¬
lisation of the crude commercial acid first with ether and then with
water. The oxalic acid, which is difficult to dissolve in cold ether,
is dissolved in Soxhlet’s apparatus in extraction shells. The
contaminating calcium and potassium salts remain completely
in the filter shells. — Pharm. Gentralh., xxxviii., 214.
SOME FORMULA FOR SYNTHETIC PERFUMES.
Lilac.
Ess. Jasmin and Ess. Rose . . . of each 5 fl. ozs.
Ol. Ylang Ylang . . . 60 minims.
Heliotropine . . . 20 grains.
Ess. Tuberose . 10 fl. ozs.
Ess. Civet . . 1 drachm.
Terpineol . 6 fl. drachms.
Ess. Ambrette . 1 fl. oz.
Glycerin . 4 drachms.
Rectified Spirit . .to 25 fl. ozs.
Hyacinth.
Geranyl Acetate . 3 31.
Ess. Jasmin . 10 ozs.
Vanillin . 10 grs.
Oil Neroli . 20 31.
Hyacinthine . 25 31.
Ess. Ambrette . 1 oz.
Coumarin . 20 grains.
Ess. Rose . 3 fl. ozs.
Glycerin . 4 drachms.
Rectified Spirit . . . to 25 fl. ozs.
Violet.
Essential Oil of Orris . 5 31.
Essential Oil of Sweet Orange . 1 minim.
Essence of Tuberose . 2 ozs.
Essence of Orris . 5 ozs.
Oil of Lavender . 2 Tfl.
Oil of Ylang Ylang . 10 31.
Glycerin . 4 drachms.
Ionone . 30 minims.
Anethol . * . . 2 minims.
Essence Cassie . 4 drachms.
Oil of Lignaloe . 3 rtf.
Heliotropine . 10 grains.
Essence of Violet . to 25 fl. ozs.
Heliotrope.
Vanillin . . . 10 grs.
Oil of Ylang Ylang . .. . . 30 31.
Oil of Lignaloe . . 30 31.
Ess. Tuberose . . „.... 5fl. ozs.
Ess. of Ambrette . 2 fl. ozs.
Ess. Jasmin . 10 fl. ozs.
Glycerin . 4 drachms.
Heliotropine . 90 grains.
Oil of Sweet Orange . 2 31.
Otto of Rose . 5 31.
Oil of Bitter Almonds . 5 31.
Coumarin . 30 grs.
Ess. Civet . 2 drachms.
Rectified Spirit to produce . 25 fl. ozs.
Alkaline Iodides and Bromides.
These compounds are prepared by Knobloch ( Pharm.
Zeit.) by an ingenious method, which obviates the simulta¬
neous production of iodates and bromates, and the necessity
for their subsequent reduction. The process depends upon
a series of reactions, in the first of which ferroso-ferric
bromide or iodide is formed. This is decomposed by excess
of milk of lime, which precipitates the iron, as magnetic oxide
The solution of calcium haloid salt is then treated with an equiva¬
lent quantity of an alkaline sulphate, when the insoluble calcium
sulphate is precipitated, and the alkaline iodide or bromide goes
into solution. The following details of the method for preparing
potassium bromide is typical of all, substituting the equivalents of
iodine or of sulphates of the other alkalies if it be desired to
produce other salts : — Iron filings, 8 parts, are introduced into a
flask with 20 parts of water ; bromine, 16 parts, is slowly run
in, the mixture being kept cool meanwhile. When the action slackens
it may be aided by a gentle heat if necessary until the green solution
of ferrous bromide is obtained ; this is decanted, and 4 parts of bromine
added, followed by a slight excess of milk of lime, which precipi¬
tates the whole of the iron as magnetic oxide, calcium bromide
going into solution. Potassium sulphate, 21 parts, is then
added, and the whole mixture heated on the steam-bath for some
hours. The hot solution is filtered, washed with a little hot water,
the small amount of sulphate present in the filtrate precipitated
with a slight excess of barium bromide, potassium carbonate added
to faint alkalinity to precipitate traces of barium or calcium, and
finally, after filtration, the liquid is neutralised with hydrobromic
acid, concentrated by evaporation, and crystallised. The potassium
bromide so obtained is pure.
Clove Pink.
Hyacinthine . . .
Ess. Rose . . .
Otto . . . .
Coumarin . . . .
Essential Oil of Almonds .
Heliotropine . ............
Caryophylline . . .
Oil of Cloves . . .
Ess. Jasmin .
Ess. Jonquille . . . . „ .
Oil of Orris . . . . . . . .
Glycerin . . . ....
Terpineol .
Rectified Spirit . . ...to
5 31.
2 fl. ozs.
3 31.
10 grs.
5 31.
10 grs.
60 31.
4 31.
15 fl. ozs.
2 fl. ozs.
2 31.
4 drs.
5 31.
25 fl. oz3.
Maybells.
Coumarin .
Heliotropine .
Caryophylline and Oil of Lignaloe . . of each
,, „ Sweet Orange . . .
,, ,, Neroli .
Terpineol .
Ess. Jasmin .
,, Jonquille .
,, Rose . . .
,, Cassie .
,, Ambrette .
Glycerin .
Rectified Spirit to produce . . . . . .
“ 1897.”
Terpineol . . .
Oil of Lavender . . .
„ ,, Bergamot.. . . . .
,, ,, Sandal and Caryophylline. . . .of each
Ol. Ylang Ylang . * .
,, Petit Grain .
„ Pimento .
Heliotropine . „ . .
Gardenia . . .
Aubepine . . .
Vanillin . . .
Nerolin . . . . .
Ess. Jasmin . .
,, Cassie . . . . . . . . .
,, Civet. . . .
,, Orange. . . . . . —
Glycerin . . . . . .
Rectified Spirit to produce .
10 grains.
40 „
20 minims.
2 „
5 „
2 drachms.
8 ozs.
4
0 »
2 „
4 „
4 drachms.
25 fl. ozs.
2 drachms.
4 drachms.
30 31.
30 31.
20 31.
10 31.
20 31.
20 grains.
5 „
10 minims.
30 grains.
10 „
12 fl. ozs.
4 „
30 minims.
4 fl. oz.
4 drachms.
25 fl. ozs.
[May 22, 1897
PHARMACEUTICAL JOURNAL.
461
PARLIAMENTARY NOTES AND NEWS-
Sale of Food and Drugs. — The consideration of Mr. Kearley’s
Bill to amend the law on this subject having been relegated to the
dog days, Mr. Jeffreys (Basingstoke) has very pertinently been
inquiring when the Government intends to bring in the promised
official measure to effect the much-needed amelioration of the
present condition of things. In replying to the inquiry, Mr.
Balfour made it appear that the President of the Local Govern¬
ment Board is responsible for the delay — a political example of
the intractability of partner Jorkins. At any rate, the Leader of
the House is in consultation with the Department, and though he
cannot yet name a day for the introduction of the Bill he may in
time be able to make Mr. Chaplin realise that Her Majesty’s
Government are pledged to introduce a Food and Drugs Amend¬
ment Bill, and that unredeemed pledges are not good stock for a
Ministry to have in hand.
Examiners in the Education Department are apparently too
much of a family party to quite please those who sniff a monopoly
in every centre of human activity. Captain Norton, the Liberal
representative of West Newington, asked the Vice-President of
the Committee of Council on Education (why not call him Minister
for Public Education ?) whether the duties of the examiners
aforesaid could not be very well done by the Upper Division Clerks
in the various departments of the Civil Service, and whether, too,
Sir John Gorst could recommend that in future the appointment
of examiner be thrown open to competition. Sir John’s reply was,
as might be anticipated, in the negative. The examiners are
appointed by the Lord President of the Council, and it is not
believed to be possible to secure by open competition that combi¬
nation of special qualifications which the position demands. The
duties of the examiners, added Sir J. Gorst, are not analogous to
the work of Upper Division Clerks. Captain Norton will probably
take the first opportunity of returning to the charge, and he will
find plenty of volunteers ready to join in any attack on the
educational administration of the country.
The Copyright (Amendment) Bill, which has just made its
ddbat in the House of Lords, under the guidance of Lord Monks-
well, contains good news for contributors to the Pharmaceutical
J ournal and similar periodicals. Perhaps the authors are blissfully
ignorant of the fact, but at present no writer can publish sepa¬
rately an article he has contributed to a journal or magazine until
after the expiration of twenty-eight years — a term which affords a
reasonable time for reflection. Lord Monkswell’s Bill would effect
a reduction of this period of probation to three years. In fact,
the copyright of any article is to be vested in the author,
subject only to the proprietor of the magazine to which
it is contributed having the right — the sole right, of publishing it
during three years as part of the magazine. The copyright of
articles or essays forming part of encyclopaedias remains as
heretofore, vested in the publisher or owner of the work.
Lecturers will Rejoice in the noble Lord’s proposals to repeal the
old Copyright Act of 1835, and to substitute provisions which shall en¬
title the author of any lectureto copyright therein, as if itwereabook.
The lecturer will have the satisfaction also of reserving to himself
the exclusive right of delivering the lecture in public. Even more
despotic may he become if he so wills it, for the Bill would permit
him to prohibit the harmless necessary newspaper reporter from
publishing a report of the lecture. What is sauce for the lecture-
room is sauce for the pulpit, and sermons are therefore included
in the category of protected ai tides. We understand that the
Bill confers no privileges in respect of the kind of lectures to which
Mrs. Caudle was addicted.
London’s Teaching University has not yet been created, but
the prospect has distinctly improved since last Session. Replying
to Mr. Brynmor Jones (Swansea) on Monday last, Mr. Balfour
stated that the Lord President of the august body which fosters
the mental development of the nation hopes to introduce a Bill,
similar to last year’s University of London Bill, into the House of
Lords shortly. The new Bill is at present the subject of negotia¬
tion between representatives of the various interested parties, and
there is reason to expect that the opposition hitherto shown to the
scheme in certain quarters will be overcome, and all obstacles to
the passage of the measure removed.
EXTRACTS FROM CONSULAR REPORTS-
Obstacles to British Trade. — In his observations on British
trade with Servia, Consul Macdonald remarks that experienced
merchants in Belgrade are of opinion that one of the chief impedi¬
ments to British trade with Servia lies in the unwillingness or
inability of our manufacturers to quote their prices “franco Bel¬
grade,” and to their failure to adopt the metric and decimal systems
of measurement and price. Complaints are also frequent of
unnecessary delay in despatching goods ordered from England.
The question of measures and prices has been settled in individual
cases in favour of metres and francs, and what is possible and
advantageous to one must be equally so to all. The prompt
despatch of goods on order seems too absurd to call attention to,
but Belgrade merchants consider it a substantial difficulty in the
way of our trade.
British Trade with Maranham (Brazil). — Consul Kanthack,
in his report on the trade and commerce of Maranham, publishes a
return showing the approximate value of imports at Maranham
from July 1, 1895, to June 30, 1896, as compared with the year
1894-95. The return shows a very considerable decline in imports,
and the largest proportion of that decline is borne by imports
from Great Britain, which show a decline of 38 -4 per cent., as
against 23-23 per cent, from the United States, and 21 ‘80 per cent,
from Portugal. On the other hand, imports from Germany (vid
Hamburg) show an advance of 117 '4 per cent., and from France
49 '6 per cent. The decline in imports from Great Britain is in
part accounted for by the fact that the goods manufactured in
Brazil are those which formerly were imported from this country ;
nevertheless, the report confirms the general impression as to the
strides Germany is taking in pushing her trade.
Bismuth. — The bismuth industry of Bolivia, according to the
report of Consul Alfred St. John, is in the hands of one firm
which has been acting in concert with other producers in Europe
for the purpose of establishing a monopoly of that article.
Drugs, Chemicals, and Colours imported into Servia in 1895
were estimated at a value of £50,586, the value of various chemi¬
cals and drugs being £14,581, and that of made-up medicines and
chemical preparations £24,406. Dyes were valued at £11,598;
£5668 being for raw colours. Austria-Hungary furnished these
goods to the amount of £42,734, whilst British contributions con¬
sisted only of a few hundred pounds’ worth of ammonia, acids,
varnish, scented oils, and made-up medicines.
The Adulteration of Olive Oil evidently has not the sanction
of the Italian Government, Consul-General Chapman being informed
that in some special cases notice was given to foreign Governments
that shipments of olive oil, which was declared pure, had
been sent off mixed with oil of other seeds. Proceedings were con¬
sequently instituted abroad against shippers, who were condemned
to the payment of heavy fines and costs. Such frauds have thus
been stopped with the full approval of the honest exporters of
olive oil.
Soap Manufactories in Greece are reported by Consul Maxse
to number thirty-seven, and the value of the plant employed at
£45,625. During the last three years the value of soap exported
has risen from £12,000 to £28,000. The total amount of soap
produced last year was 8125 tons, of which 1850 tons were exported.
The import of soap into Greece, except sanitary and perfumed
soap, is very small, and the total of all soap imported sank from
58 tons in 1890 to 53 tons in 1895. Turkey imports by far the
largest quantity of Greek soap. The Government was peti¬
tioned to permit the importation of olive refuse from
abroad for the purpose of making green soap, but the entry
was refused on account of the fear of introducing phylloxera into
Greece. The demand for olive refuse is larger than the native
supply, arid the importation is only permitted from the islands of
the Archipelago and one or two more ports in Asia Minor.
An English Company was formed in 1896 to develop and
work magnesite quarries in Greece and in particular the Gadladaki
magnesite quarry in Euboea. It has a capital of £100,900 in £1
shares. '
PHARMACEUTICAL JOURNAL.
[May 22, 1897
NOTICES TO CORRESPONDENTS.
All Communications for the Pharmaceutical Journal’ must
be Addressed to the Editor, 17, Bloomsbury Square, London,
W C , and not In any case to Individuals supposed to
be connected with the Editorial Staff; no responsibility
can be accepted unless this rule be observed. Communica¬
tions for the Current Week’s Journal should reach the
Office not later than Wednesday, but news can be Received
by Telegraph until 4 p.m. on Thursday.
Advertisements and orders for copies of the ‘ Pharmaceutical Journal’ must
be addressed to the Publishers, 5, Serle Street, Lincoln s Inn, London, W.C.
Cheques and money orders should be made payable to Street Brothers.
Correspondents should write in ink, on one side of the paper only, and must
authenticate the matter sent with their names and addresses— of course not
necessarily for publication. No notice canbe taken of anonymous communications.
Drawings for illustrations should be executed twice the desired sixe ; clean
sharp lines being drawn with a pen and liquid Chinese ink. Shading by
washes is inadmissible. Photographs can be utilised m certain cases.
Names and Formula should be written with extra care all systematic names
of plants and animals being underlined, and capital letters used to commence
generic but not specific names.
Queries addressed to the Editor will be replied to in the Journal as early as
possible after receipt, but it is not always possible to publish answers the same
week as the queries are received.
LETTERS TO THE EDITOR.
Arsenical Soaps.
g;r _ Wibli reference to your report in last week’s Pharmaceutical
Journal of the case of Houghton v. Taplin will you allow me to
inform your readers and chemists generally that ever since the
first prosecution took place last November, the amount of arsenic
has been increased in Dr. Mackenzie’s arsenical soap and is now
readily found on analysis ? At the same time I should like to say
that it is not pretended that the small amount of arsenic alone
produces the beneficial results claimed for the soap, but the
addition of special ingredients gives it its distinctive character.
London Bridge, S.E., May 14, 1897. S. Harvey.
Medicine Stamps — A Suggestion.
Sir —May I trespass on your space in order to bring before the
trade an idea which I think, if it could be carried out, would
prove to be of great benefit to chemists, proprietary medicine
dealers, and proprietary medicine makers? The cutting of
proprietaries has now got to such a pitch and is so general, that
the leverage to attract customers has been almost entirely taken
from the so-called drug stores, and I am quite sure that even they
do not believe in selling goods without a profit ; this is proved by
the systematic method they have of substituting. My idea is
that our Society should approach the Inland Revenue authorities
and ask them to rearrange the prices of patent medicine stamps,
and instead of having these for 1 \d., 3d., and so on, to have them
for 1 d 2d., and 3d., for articles to sell respectively at 9a., Is. 6a.,
and 2s. 9 d. I think the change would bring in an increased
revenue, and would prove to be a benefit to all concerned in patent
medicines. If the Pharmaceutical Society does not see its way
to take this up, perhaps the P. A.T. A. might. If the prices could be
rearranged as I suggest, a reasonable pront could be allowed and
secured to dealers, and I think the manufacturers would be better
able to see their way to join the P.A.T.A. No doubt there will
be many difficulties to overcome in order to carry the matter out,
but I think the idea is worth ventilating, and I hope that chemists
will not fail to express their opinion about it.
Meivark-on- Trent. John H. Smith.
The Need of a Chemists’ Protective Association.
gir> _ After reading in the last issue of the Pharmaceutical Journal
the reports of legal cases, showing what individual chemists have
experienced in the ordinary and legitimate course of business, and
necessarily causing much expense and annoyance, I think many of
your readers will share the opinion that there ought to be some
means devised whereby chemists can meet business imputations
preferred against them without so much individual loss
as at present. When I was summoned for selling a
tablet of arsenical soap of a proprietary nature, I thought the
manufacturers would in common justice have assisted me in the
defence, but no such course was adopted, and I was compelled to
bear the responsibilities alone. As reported in your Journal, I
incurred thereby in legal expenses £22, besides other losses ; the
public generally do not read newspaper reports without prejudice.
As the outcome of this I sued the manufacturers for expenses
incurred and damages, and was successful in sustaining the
action before the County Court judge. From time to time
cases somewhat on a par with the arsenical soap and
lime juice and glycerin prosecutions are sure to occur, so 1
think it behoves every chemist to be prepared against such con-
tino-encies. To meet this I would suggest that a “ Chemists’ Pro¬
tective Association ” be formed, for the mutual protection of its
members by defending cases which the committee of the association
so formed deems legitimate and desirable. Apart from actual
legal expenses, very little would be expended, so that the
subscription of its members need only be a trifle. I hope
those of our fraternity who favour this proposal will in¬
timate the same to me by letter, and I will then take initiative
steps to arrange a preliminary meeting to discuss the proposal on
its own merits. This project concerns every chemist in business,
so I trust interest will not be wanting, and that a good response
will be made at an early date, with any further proposals or
suggestions advantageous to the desired end.
Kingston-on- Thames, S. W. , May 17, 1897. Alfred Higgs.
An “Enquirer’s” Question Answered.
gir —The would-be funny man from Biarritz is either wanting-
in ordinary schoolboy intelligence, or he has omitted to read the
original oucry in the J^hcivnictccuticctl Jouvncil of May 1, the result
being that he has grossly misrepresented the facts of the case.
His witticisms are therefore as pointless as his innuendoes are
unwarranted. But there is hope for « Enquirer ” yet He has
not gone abroad for nothing ! He has already learnt that grosse
is the feminine form of the adjective “ gros,” and he may some
day realise that the substantive “gros” refers to an old French
weight. He may even learn decent manners if he stays in France
^BrigUo^May 17, 1897. C. S. Ashton.
The Sale of Morphine.
girj _ With reference to your “annotation” upon the case of
morphinism at Enfield, the quantity of four ounces appears to
refer to the solution, not to the pure salt of the alkaloid. It was
not obtained locally, but from a chemist at a distance. . I am
sending you a marked copy of the local paper, which gives full
particulars. I may add that the police, in working up the case,
produced several articles of small value which had evidently been
taken from my counter ; petty thefts were also discovered at
several shops in the town.
Enfield Town, N., May 14, 1897. F. Goldby.
“A Royal College of Pharmacy.”
gir)_ All well-wishers of the profession view the new regulations
for the Minor examination with pleasure, but the same cannot be
said of the proposed bye-laws relating to the Major. The Major
examination cannot be said to have been a success. The undoubted
reason for this is that from a pecuniary standpoint the present
examination is worthless. From motives of curiosity I have made
a point of asking persons whom I have met, and who would be
likely to know, whether they were aware there was any difference
between a chemist and a pharmaceutical chemist. I
have yet to meet the man outside the medical profession
who knows any such difference exists. The general impression
is -that if there are two diplomas, the title “chemist,” without any
qualifying adjective, would be the better of the two. The public
might understand a difference between druggist and chemist, but
the word pharmaceutical is un-English, and John Bull has no
relish for names he is afraid to pronounce, and views their use by
others as a sign of mental weakness. Further, the diploma is
worthless for the purpose of obtaining public scientific appoint¬
ments. Thus little inducement is held out to young men to pro-
ceed to the higher examination, and yet the Council appears to be
about to lower the standard. Such a step will, I am sure, reduce
the examination to an absurdity. What is required is to make
the examination equal to the F.I.C. , and thus fit men who
pass it to hold scientific appointments. Such a step would,
I feel sure, tend to increase rather than diminish the
number of candidates. I cannot see why the Society
should view with any alarm the small number of candidates.
I believe that the percentage of men who enter for the Major is,
MAY 22, 1897]
PHARMACEUTICAL JOURNAL.
463
quite as great, for instance, as that ot veterinary surgeons who
proceed from Membership to Fellowship of their College. A few
weeks ago you remarked on the British love of seeing letters after
the names of professional men, and although this may be weakness,
it is an undoubted fact that such letters are viewed by the public
as symbols of qualification. And yet in our profession one barely
ever sees these imposing signs, although I know of no profession
in which they would be of more service. The public cannot see
the difference between Shoes, cash chemists, and Brown, store
chemist, but they would see there was a difference between Shoes,
cash chemists, and Mr. John Brown, Ph.C., M.P.S.
And yet my brethren of the pestle, instead of endeavouring to
give the public the impression that there is a wide gulf between
a store and a chemist, do their best to further the idea that there
is no difference whatever, and therefore call themselves store
chemists. In fact, in so little respect are our diplomas held that
even our most prominent pharmacists appear to be ashamed of
them. They would scorn M.P.S., but they fish for F.C.S., and
even descend to F.I.Inst. No wonder learned sheriffs ask, What is
the Pharmaceutical Society? No wonder the man who places
M.P.S. on his labels is expected to know all about photography,
“ being a member of the Photographic Society,” or is taken to be
a Quaker, “ being a member of the Peace Society.” The present
Major examination would become much more popular if
some of our prominent men would set the fashion of
using the title Ph.C., which is certainly more honour¬
able than F.I.Inst. or F.C.S. The Society might do
something in the matter by using the title on its communications
to members. I know the man in the street has much more respect
for a college than for a society, and I firmly believe if the founders
of the Society had styled it the Royal College of Chemists there
would scarcely be a chemist in the country off the rolls. M.R.C.C.
looks so imposing. I am no lover of such letters myself, but I
believe the Society would benefit immensely by putting sentiment
on one side and changing its name ; indeed I can conceive of no
better way of celebrating Her Majesty’s Jubilee. I prefer the
“ Royal College of Chemists” to the “Royal College of Pharmacy,”
because the former would be better understood by the general
public. A “ College ” in preference to a “ Society ” would certainly
be more in accordance with the titles of the other great governing
bo lies of the medical profession.
May 17, 1897. Fyton.
The Minor Examination Standard.
Sir, — For a long time there has been much complaining as to
the standard of knowledge required for the Minor examination,
and as to the way in which such knowledge is elicited by the
examiners. We seniors hear effusive declamations and pitiful
descriptions almost ad nauseam from rejected candidates as to the
trying ordeal arranged for them by the examiners. In support of
these complaints we see the constantly recurring large percentage of
failures. In this state of affairs the average Minor candidate thinks his
task a hard one, and, should he have failed several times, looks upon
his chance of passing as something very problematical. All this
tries his patience, jeopardises his reputation, and hurts his pocket.
Now, what is the remedy? On all sides we hear it said that the
scope of the examination is too high, too severe, too professional ;
that it has too wide a range. Indeed, only a few weeks ago a
worthy member suggests that the questions set should be entirely
found within the boards of the Pharmacopoeia. As an
old member of the Society, I have watched these matters
and should have expressed my opinion thereon long ago, but have
thought surely some of our shining lights would rise and show the
way out of the fog. But no, the grumble goes on without ceasing.
I would now ask my young friends and those who support them
what is the use of complaining about that which they cannot alter?
However and whatever they think of the examination or examiners,
are they not utterly powerless to alter the one or conciliate the
other ? Seeing then the difficulty cannot be lessened, the question
is how to grapple with it, that is, how to pass ?
Do the candidates go the right way about their work ? I think
not. Their aim should be to gain that full, perfect, and sufficient
knowledge which would render examination a very formal affair.
Do candidates get this knowledge or do they properly try to get
it ? Seldom so, I think. Is it not more usual by coach, by tips,
by cribs, by hints, to grind, to get up, to read as much as will
squeeze a man through ? Trained in this manner, although well
primed with the newest theories of the day and the
tips of the hour, is there any wonder failure results ?
Rather let the candidate at the commencement of his business
career lay a broad and solid foundation by attending extended
courses of lectures on theoretical and practical chemistry,
chemical physics and botany. If not well up in Latin and
arithmetic, let him by all means take care to improve himself
therein. On these bases let the pharmaceutical structure be raised
by going to one of the many good schools of pharmacy, and let
honest work there be assisted by diligent work in the shop.
In many shops there may be lack of opportunities, but if the
student be in earnest he will find much, if not abundance, for his
needs. In dispensing let him train himself to be tidy, accurate,
and methodical, making up the few prescriptions which come in
faithfully and with as much care and concern as if working at the
examination counter. Of course it is hard work, but do what we
will this is still a necessity in the lives of most men.
Manchester, May 18, 1897. Index.
The Brentford Glycerin and Lime Juice Case.
Sir, — There are one or two points in your note relating to the
case heard at Brentford on Saturday last which call for comment.
I have on a former occasion pointed out that it is not I, but the
Inspector, who is responsible for the selection of the samples that
he takes, and also for the institution of proceedings. If, as I do
not suggest, the Inspector made an error of judgment in applying
for a summons, the Magistrates before whom the applica¬
tion was made might have refused to grant it. As to
your statement that the Somerset House chemists supported
their certificate to the satisfaction of the Bench, it is equally true,
as shown in your report on page 416, that the Bench were satisfied
with the accuracy of my analysis, but this you do not state. This
being so, I do not think it is fair to say “ the public analyst has
undoubtedly made a mistake.” I should like to add that my
analysis would have been supported by Mr. Otto Hehner, who
was, however, unable to give evidence, as he was unfortunately
detained abroad. As to the confirmatory evidence of Mr. Michael
Conroy, I would point out that his evidence merely went to the
length of showing what in fact I admitted might have been the
case, that there were traces of glycerin present. He made no
attempt to estimate the quantity.
London, May 18, 1897. Edward Bevan.
ANSWERS TO QUERIES.
Special Notice. — Scientific, technical, legal and general information required
by readert of the 1 Pharmaceutical Journal ' will be furnished by the Editor as far
as practicable, but he cannot undertake to reply by post. All communications must be
addressed “ Editor , 17, Bloomsbury Square, London, W.C.," and must also be authen¬
ticated by the names and addresses of senders. Questions on different subjects should
be written on separate slips of paper, each of which must bear the sender s initials or
pseudonym. Replies will, in all cases, be referred to such initials or pseudonyms
and the registered number added in each instance should be quoted in any subsequent
communication on the same subject.
Botanical. — Lepidium perfoliatum. [Reply to E. W. P. — 94/22.]
Botanical. — Geranium, striatum. [ Reply to Cornubia. — 95/5.]
Botanical. — 1. Valerianella olitoria ; 2. Myosotis collina ;
3. Veronica serpyllifolia. [Reply to Secundus. — 94/1.]
Register. — No, the book is only corrected to the end of
December. [ Reply to Cardiff. — 94/24.]
Books Wanted. — We are inquiring about works on the subject
you mention. The book on midwifery does not appear to be in
the Library. [Reply to Penny Stamp. — 93/20.]
Pink Coloured Hyacinth. — Tint the product of the formula
given at page 460 with a little tincture of red sandal wood,
alkanet root, or cochineal, according to the colour you require.
[Reply to Pestle. — 92/45.]
Red Powder Used by Shoe Manufacturers. — The powder
which you send is nothing but impure ferric oxide. Probably a
good sample of red Armenian bole will answer all the purposes you
require. The powder is in an extremely minute state of division.
[Reply to E. C. H. — 93/26.]
464
PHARMACEUTICAL JOURNAL.
[May 22, 1897.
Mineralised Methylated Spirit. — Presumably the effect
noted is produced by the mineral naphtha added to the spirit.
Retailers are not now permitted to sell or have on their premises
unmineralised spirit. [Reply to H. H. — 95/6.]
Fusible Alloys.— (A) Bismuth, 8 ; lead, 5 ; tin, 3. Melt
together ; fuses below 212°. (B) Bismuth, 2 ; lead, 5 ; tin, 3.
Melts in boiling water. (C) Lead, 3 ; tin, 2 ; bismuth, 5. Melts
at 197° F. [ Reply to Penny Stamp. — 93/19.]
Flower Cement. — A saturated solution of sandarac in methy¬
lated spirit is used. Probably an ethereal solution of ordinary
yellow resin would answer better, as it would “ set ” almost imme¬
diately. [ Reply to R. S. L. — 94/16.]
Cheap Hair Wash. — Soft soap, 1 ounce ; proof spirit, 2 ounces;
oil of Myrcia acris, 25 minims ; tincture of quillaia, 2 drachms ;
distilled water, 8 ounces. Dissolve the soap in the spirit, add the
oil to the tincture, mix, and add the water. [ Reply to A. M. — 94/19.]
Ice Cream. — The information regarding the preparation of ice
cream appeared in the Pharmaceutical Journal for April 10 last, as
a very moderate expenditure of time and trouble in referring to
the weekly indexes would have shown. [ Reply to Verax. — 95/15.]
_ British Pharmaceutical Conference. — The annual subscrip¬
tion is seven shillings and sixpence, and you can obtain all the
particulars you require by applying to the Assistant Secretary,
B.P.C., 17, Bloomsbury Square, W.C. [ Reply to S. H. — 93/23.]
Reaction in Making Lin. Potass. Iodidi c. Sapone. — In
mixing curdsoap (sodium oleo-stearate) andpotassium iodide double
decomposition results, and a soft soap (potassium oleo-stearate) and
sodium iodide are formed. [Reply to C. T. J. — 94/10.]
Excipient for Pill. — The prescription, “Creosoti, gtt. xviii. ;
pulv. semin. conii, 3j. ; pulv. Doveri, 3ij. ; m.ft. pil. , xxxvi., sec.
art. should be massed with a mixture of 10 grains of powdered Cas¬
tile soap and 5 grains of heavy magnesia. [Reply to C. T. J.— 94/10.]
To Coat Horse-Balls with Gelatin.— Make a solution of 1
part of gelatin in 4 parts of water, and add enough soluble black
to give the requisite colour. Fasten the balls to pieces of stout
wire (knitting needles answer well), dip in the solution, rotate, and
dry. Some use sugar with the gelatin, but it is doubtful whether
this offers any advantage, since it takes much longer to dry.
[Reply to R. H.— 92/39.]
Testing the Sight. — It is impossible, within the limits of our
space, to give you anything like satisfactory data as to sight¬
testing, and to do it efficiently requires considerable training and
practice. The best book on the subject is ‘ The Refraction of the
Eye,’ by Hartridge, published by J. and A. Churchill, of New
Burlington Street. [Reply to A. H. 0. — 84/17.]
German Ph.D. Degree. — You can obtain this degree at one of
the numerous German universities after about two years’ residence,
during which lectures and laboratory courses in the selected sub¬
jects must be attended. Proof of good general education must be
submitted prior to entering upon the university course, and the
degree is granted after completing some original investigation
and passing an examination in the subjects selected for study.
Apply to the secretary of the university you decide upon for
detailed particulars, as these vary somewhat in each case.
[Reply to Dispenser. — 94/42.]
Saxin. — We are indebted to Messrs. Burroughs, Wellcome and
Co. for the information that “Saxin” is the name given to a
powerful sweetening agent recently introduced and issued in
tabloid form by that firm. It is said to possess a sweetening
power about six hundred times greater than that of sugar and is
most delicate in flavour, being thus rendered acceptable to many
patients who have hitherto refused all sweetening agents other
than sugar. A J-gr. “ Saxin ” tabloid may be substituted for each
lump of sugar in the case of patients suffering from diabetes, gout,
obesity, glycosuria, etc. By this means the harmful effects of
sugar will be avoided, and “ Saxin ” itself is understood to have no
harmful action on the system. [Reply to H. D. K. — 93/2,]
Pulv. pro Pil. Rhei Co. — Two parts of powdered pill and one
part of excipient gives approximately the pil. rhei co. mass of the
B.P. The other pill powders are usually dispensed with just
sufficient excipient to mass, and the mass so made is, of course,
weighed before rolling. If you have much of a given mass to
make frequently you can note the quantity of excipient required
and add just that amount each time. [Reply to C. T. J.— 94/10.]
Perfumes from the New Synthetic Bodies. — The articles you
name — heliotropin, coumarin, terpineol, ionone, etc., — are scarcely
new now, for, except the last-named, they have been known for
some years. All of them are practically invaluable for modern
perfumery, and are particularly suitable for blending, since their
aroma is pure and distinctive, giving what may be termed a very
sharp “ odour reaction ” when suitably combined. (See formulae
at p. 460.) [Reply to I. H. H. — 92/29.]
Enamel Varnishes. — Possibly something on the following
lines will suit you : — Make a basis of copal varnish, 2 ; linseed oil,
3 ; turpentine, 4 ; boiled oil, 5. Mix in with a muller the pig¬
ments such as zinc white, white lead, Indian red, yellow chrome,
etc. , according to the colours you want, thinning down from time
to time with a little more turps. The powdered pigments must
be in the most minute state of division, and thoroughly mixed.
[Reply to Enamel. — 92/44.]
Gelatinisation of Tincture of Kino. — According to Rother
and others, the gelatinisation of alcoholic tinctures of kino is due
to oxidation. This is hindered by the presence of glycerin. That
body was added to the formula of the B.P. 1885, and since then
we have not experienced any difficulty from this pectinisation.
Probably your tincture did not contain glycerin. After it has
once gelatinised we fear you cannot do anything to it to restore it
to fluidity. [Reply to C. T. J.— 94/10.]
Oxidation of Ferrous Carbonate. — This process is gradual,
and probably many intermediate combinations of oxygen are
formed before oxidation is complete, but if exposed long enough
to the air almost all the C02 is lost, and ferric oxide results, the
remaining small portion of C02 being in the form of a high basic
oxy-carbonate, but the whole process results in very complex inter¬
mediate forms, which cannot well be represented by equations
and certainly not by the one you give. Remember, equations only
serve, at the best, to indicate the ultimate result of chemical action,
and often do not show what actually takes place at all in the
intermediate reactions. [Reply to C. T. J. — 94/10.]
Sale of Benzine. — Judging from the terms of the Petroleum
Act, benzine should be sold in sealed vessels exclusively, though
that fact is not expressly stated. It is stipulated that the aggre¬
gate bulk kept shall not exceed three gallons, and that the spirit
must be kept in separate glass, earthenware, or metal vessels, each
of which contains not more than a pint, and is securely stoppered.”
Those vessels, if sold or exposed for sale, must bear labels stating
the description of the “petroleum,” with the addition of the words
“ highly inflammable,” together with the name and address of the
vendor. Taken together, these restrictions seem to indicate the
undesirability, if not the illegality, of retailing the spirit otherwise
than in sealed vessels. [Reply to A. H. P. — 94/15.]
Glycerin and Cucumber.— The following has given great
satisfaction when used : Take of white castile soap, 1 oz. ;
cucumber pomade, 4 ozs. ; glycerin borax, B.P.,‘ 3| fl. ozs. ;
essence of jockey club, 1 fl. oz. ; distilled water, 63 ozs. Dissolve
the soap in part of the water, and having mixed gradually with
the cucumber pomade in a hot mortar, rubbing the whole into a
creamy product, then add the remaining ingredients and the rest
of the water. Strain through muslin if necessary, and stir gently
until perfectly cold. If there is any tendency to separate, prevent
this by using tragacanth powder, 24 drachms or less, which should
be moistened with a little spirit and made into a mucilage with the
soap solution before adding the other ingredients, as mentioned
above. [Reply to Khama. — 94/2.]
COMMUNICATION S, LETTERS, etc., have been received from
Messrs. Ashton, Bayley, Bevan, Butler, Byles, Chambers, Clark, Cracknel!,
Dordon Durrant, Dyson, Eberlin, Elms, Flatters, Glyn-Jones, Goldby, Hall,
Harvey, Heanley, Higgs, Howorth, Hudson, James, Lovatt, Newbery, Oliver,
Polley, Bees, Reeve, Reynolds, Robinson, Shapley, Shepherd, Skinner, Smith,
Taylor, Tschireh, Walker/ Wallwork, Wand, Watson, Willson, Wood.
PHARMACEUTICAL JOURNAL,
465
E MONTH.”
IM A. W. Titherley states that the beha-
of metallic rubidium towards ammonia is
^Similar to that of other alkali metals, such as
fin, and sodium, but its action is not so energetic
as that of lithium, though more marked than that of either of the
others. The formation of rubidamide commences in the cold, when
small pellets of rubidium are exposed to a slow stream of pure
gaseous ammonia, but on heating to between 200°-300° the action
proceeds more rapidly. Hydrogen is continually evolved, and the
conversion is complete in a very short time. On cooling, the melted
amide solidifies to a white, crystalline, glistening mass of small
plates, very similar to those of potassamide. Lithamide crystal¬
lises in needles. The formula of rubidamide is RbNH2, its
melting point is 285°-287° (sodamide, 155° ; potassamide, 270°-
272° ; lithamide, between 380° and 400°), and in the fused state it
resembles the other amides of the alkali metals, forming a
greenish-brown, oily liquid, which has1 a tendency to creep. It
assumes a darker colour on heating more strongly, owing, pro'
bably, to slight dissociation. Rubidamide attacks glass when
heated with it, being converted into rubidium silicate; it is ex¬
cessively deliquescent ; violently decomposed by water, giving
ammonia and rubidium hydroxide ; and is less violently acted on
by alcohol, giving ammonia and rubidium ethoxide. Complex
organic matter is at once charred by rubidamide, whilst organic
compounds of an amidic or faintly acid nature evolve ammonia,
and suffer replacement of a hydrogen atom by rubidium.— Journ.
Chem. Soc., lxxi., 469.
Experimenting with highly purified sub-
Properties stances, W. A. Shenstone finds that, practically
of speaking, the action between mercury and
Purified chlorine, bromine or iodine, does not depend on
Substances. the presence of water vapour. He is less
certain whether the presence of moisture is
necessary for producing ozone from oxygen, and as ozone changes
into oxygen much more rapidly in the absence of water vapour
than in its presence, he thinks that fact disposes of the idea that
all chemical change may be impossible, except in the presence of
water. It remains to be seen, however, whether this is true of
any particular class or classes of change. — Journ. Chem. Soc.,
lxxi., 471.
To determine the moisture in soaps and other
Drying Sensitive sensitive organic substances C. C. Parsons uses
Organic an oil-bath, putting the substance directly into
Substances. a weighed quantity of hot oil, and weighing
again after the moisture has been driven off. It
is best to use neutral paraffin oil, without any admixture of animal
or vegetable oils or fats, or mineral substances, and with specific
gravity 0'920, flash test 435°, fire test 500°, and boiling-point about
550°. The object of the high fire test is that the oil
should be so freed from volatile matter that none of it will be
carried off with the moisture in the substance to be dried.
Ordinarily the whole operation may be completed in twenty
minutes. It should be conducted in a drying closet kept at
240°. First, the oil is put into an evaporating dish and kept in the
drying closet until it has the same temperature, then it is weighed
and about one- sixth the quantity of the substance to be dried,
weighed and added to it. If very moist, add in successive por¬
tions. The whole should be kept in the drying closet for a few
minutes after effervescence has ceased. On again weighing, the
loss indicates the amount of moisture driven off. — Journ. Am.
Qhem. Soc., xix., 388.
Vol. LVHI. (Fourth Series, Vol. IV.). No. 1405.
Professor Ostwald records the results of some
Crystallisation instructive experiments on the crystallisation
Of of super-saturated solutions and of super-cooled
Super-Saturated liquids. By a proper choice of substances the
Solutions. difficulty caused by accidental infection of the
solutions by dust particles was avoided, so
that crystallisation could only be induced by introducing a
crystal of the substance or of a strictly isomorphous substance.
Thus, fused salol (m.p. 39° -5) cannot be induced to crystallise
at ordinary temperatures by any of the usual means, but
a fine thread of glass lightly drawn over a crystal
of salol acquires the power Of inducing crystallisation
in the liquid. By exposing the glass to air or wiping
or warming it, this power is lost again. Spontaneous
generation of crystals, however, is impossible only within a
limited range of temperature below the melting point, and
Ostwald proposes the term “metastable” for this condition in
the liquid of stable equilibrium, except with respect to a ready-
formed crystal. At still lower temperatures, crystals form spon¬
taneously and without the presence of ready-formed nuclei, the
equilibrium being here really labile. — Zeit. f. Phys. Chem., through
Nature, lvi., 61.
Drs. J. J. Bobbie and F. Marsden, in a fifth
Corydaline communication on this compound, state that
when it is heated on a water bath with very
dilute nitric acid (about 1:20), a difficultly soluble nitrate,
C22H29N04,HN03, is first formed. On further heating, the solu¬
tion becomes dark red in colour, and soon ceases to give any pre¬
cipitate on testing with ammonia. If at this stage the solution be
allowed to cool, groups of bright yellow prismatic crystals separate
out on the sides of the vessel, consisting of the nitrate of a base —
dehydrocorydaline — differing from corydaline by four atoms of
hydrogen. The free base is very soluble in water and alcohol, and
difficult to obtain in crystals. Solutions of dehydrocorydaline
and its salts have an intense yellow colour, and give a vivid green
colour with blue litmus. Reducing agents reconvert dehydrocory¬
daline into optically inactive corydaline. Further concentration
of the acid solution until platinum chloride no longer gives a pre¬
cipitate, causes yellow coloured crystals of an acid melting at 218°
to separate out on cooling. This is temporarily named corydic
acid. It is readily soluble in hot water and in alcohol, but
insoluble in ether. Its aqueous solution has an intense yellow
colour, and does not give precipitates with any of the metals in
aqueous solution. The acid contains two methoxy-groups and is
dibasic. Its formula is C14H9N(0CH3)2(C00H2),^H20. — Proc.
Chem. Soc., 179, 101.
Behai and Francois find that most of the
Presence of Water chloroform of commerce contains water, so
and of Alcohol that when the liquid is cooled to a low-
in Chloroform. temperature small crystals of ice adhere to
the sides of the containing vessel. The
presence of water in a sample of chloroform may be easily detected
by first freezing the liquid and then, after decanting, applying a
few crystals of the double iodide of mercury and ammonium to the
spots where the crystals have appeared. In the presence of even
a trace of water the yellow crystals assume a bright red tint.
Alcohol is determined quantitatively in the following manner :
Ten C. c. of chloroform is washed in a separator, first with 4 C. c.
of pure sulphuric acid, then with three successive portions of 2 C.c.
each, so that in all 10 C.c. of acid are used. This acid solution is
then introduced into a small flask, 40 C.c. of water is added, and
20 C.c. slowly distilled over in about twenty minutes. Five C.c.
of this distillate is taken for the determination of the alcohol by
466
PHARMACEUTICAL JOURNAL.
[May 29, 1897
the following modification of Nicoloux’s method : — This quantity of
the distillate is introduced into a test tube with 2 C.c. of sulphuric acid
and placed in a glass water bath, so filled with boiling water that the
level of both the liquid in the test tube and the water in the bath
is the same. The warmed liquid is then titrated with a standard
solution of potassium bichromate containing 16 *97 grammes of the
salt per litre. Two C.c. of this solution equals O'Ol C.c. of absolute
alcohol. This is run in drop by drop until the blue tint at first
obtained changes to greenish yellow. One or two drops is sufficient
to produce this change when the reaction is complete. The
authors apply this method to the testing of commercial samples,
and find that they contain from 12 -5 to 3-75 volumes per mille of
absolute alcohol. — Journ. de Pharm. [6], v., 417.
Continuingtheir researches on the jaborandi
Piloearpidine alkaloids, Petit and Polonovski state that
in the greater part of the commercial salts of
PiloearpinG Salts, so-called “ pilocarpine ” are in reality salts of
the two bases. This is notably the case with
the nitrate, the nearly equal solubility of the two nitrates,
allowing them to crystallise together. While the greater number
of samples of commercial hydrochloride of pilocarpine contained
relatively little piloearpidine, nitrate was frequently met with con¬
taining 50 per cent, of the latter base. This impurity may be
readily detected by the lowering both of the melting point and of
the rotatory power of the solution. Thus, the pure nitrate melts
at 177-178° C., while a mixture of impure salt containing 50 per
cent, of piloearpidine nitrate softens at 140°, and is completely
decomposed at 150°. Not only does the optical behaviour indicate
the purity or otherwise of the salt, but the observed figure allows,
through Landolt’s formula, of an approximate determination of the
amount of the two nitrates present. — Journ. de Pharm. [6], v., 475.
The same authors combat the theory of Hardy
Origin and Calmels that piloearpidine is a decomposi-
Of tion product, but consider it to exist in the
Piloearpidine. plant, since in the absence of strong acids and
alkalies, the action of boiling water alone can¬
not produce it in large quantities, seeing that it has but little
action on pilocarpine, and even when heat is entirely avoided
more or less piloearpidine is always found. Again, operating under
like conditions with different species of jaborandi, the yield of pilo-
carpidine varies greatly, oscillating between 5 and 75 per cent, of
the total alkaloids ; and lastly it is usually found in greater pro¬
portion in the stems than in the leaves of the same plant. — Journ.
de Pharm. [6], v., 478.
So far from these acids being hypothetical,
Piloearpie and Petit and Polonovski have succeeded in isolating
Piloearpidic both in the free state, and find that they are
Aeids. fairly stable, particularly in the presence of
water. The bases pilocarpine and piloearpidine
are regarded as anhydrides, which, when treated with fixed alkali,
undergo hydrolysis, and the sodium salt of the acid is formed. From
this the barium salt was prepared, and this, when decomposed with
an exact equivalent of sulphuric acid, liberates the organic acids on
evaporation. These are obtained in the state of amorphous
varnishes. These acids are very soluble in water, but insoluble in
ether and chloroform ; the optical rotation is markedly lower
than that of the original alkaloid. On heating, partial de¬
hydration takes place with partial re-generation of the
alkaloids. On the addition of an acid, even dilute, the
alkaloid is rapidly regenerated. In very dilute acid solutions
the gradual dehydration of the acid may be observed by the
progressively increasing optical activity of the solution, until
ultimately it reaches the figure for the pure alkaloid. — Journ.
de Pharm. [6], v. , 481.
Petit and Polonovski are inclined to regard
Pilocarpine pilocarpine and piloearpidine as isomers. The
and figures obtained by ultimate analysis are so
Piloearpidine. close that the physical characters are by far the
most important points of difference between
the two alkaloids. If pilocarpine is regarded as the betaine of
pyridine-trimethyl-ammonium-proprionic acid,
C5H4N-
COO
I
-C—
N(CH3)3
ch3,
it is difficult to account for the fact that piloearpidine, which does
not, according to the views held by others, possess the anhydric
group, but is pyridine-dimethyl-ammonium-proprionic acid,
COOH
C6H4N - C - N(CH3)2
ch3
can yet furnish an acid by hydrolysis in a precisely similar manner
to pilocarpine. — Journ. de Pharm. [6], 5, 482.
Bourquelot finds that certain organic liquids,
Organic Liquids such as milk, blood serum, urine, egg albumin,
and and the aqueous macerations of the seeds of
Oxidation. plants and grain of cereals, have the property
of gradually destroying the oxidising properties
of such bodies as quinone ; this action takes place slowly in the
cold, but very rapidly on boiling. Thus, a mixture of milk
and solution of quinone (0-2 per cent.) heated to boiling, fails to
give any coloration with tincture of guaiacum. It appears that
in the case of milk this action is limited to the albuminoids, since
milk serum fails to prevent the oxidation of guaiacum, nor does
milk sugar have any action. Solution of albumin and of blood
serum behaves like milk. The author finds, moreover, that certain
organic liquids become active oxidisers only after the addition of a
trace of hydrogen peroxide. Thus, a maceration of Indian corn does
not colour guaiacum tincture, but after the addition of a trace of
peroxide it acquires powerful oxidising properties. Milk and blood
serum act in the same way, but urine and white of egg do not show
the same power. Blood serum requires the addition of more per¬
oxide before it will react than the other substances enumerated,
since it appears to contain a body which has a greater affinity for
oxygen than even guaiaconic acid. This property of acquired
oxidation is lost on boiling. — Journ. de Pharm. [6], 465.
This has been accomplished by Trevor
Synthesis Laurence by the condensation of ethylic
Of oxalylacetate, with ethylic bromacetate in the
Citric Acid. presence of zinc. The plastic mass thus
obtained was extracted with ether after treat¬
ment with dilute sulphuric acid, the ethyl citrate thus removed
with other esters from which it was separated by fractional distil¬
lation. From this, citric acid was precipitated as the calcium salt
after saponification with alcoholic potash. — Journ. Chem. Soc.,
lxxi., 459.
The alkaloid of Garica papaya has been further
Carpaine. examined by Van Rijn, who mentions the
method employed by the Indians in extracting
the bitter substance from the leaves. For this purpose the
boiled mass is mixed with a certain kind of clay, then again boiled
with the leaves and filtered. Carpaine is said to act as a febrifug
even when quinine is non-effective ; it possesses, however, a very
May 29, 1897]
PHARMACEUTICAL JOURNAL
4 67
strong action on the heart. On analysis the formula
C14H25N02 was obtained for the alkaloid. The hydrochlorate,
nitrate, picrate, and other salts have been obtained in crystalline
form, and several derivatives of the alkaloid have been examined.
In addition to this alkaloid a glucoside, carposide, was also isolated
from the leaves ; it forms a white mass of small needles and is very
hygroscopic. It does'not reduce Fehling’s solution until hydrolysed.
— Hed. Tjd. voor Pharm. , ix.
When reduced silver, according to Granger,
Silver is heated to 400° C. in a stream of phosphorus
Diphosphide, vapour, combination takes place, and on
suddenly cooling, maintaining the atmosphere
of the apparatus full of the gaseous phosphorus, a definite com¬
pound, AgP2, is obtained. On heating to 500° C. it becomes disso¬
ciated, but at 900° C. the elements again recombine. In this
respect it resembles gold. The diphosphide is also obtained by
heating silver chloride and phosphorus together to a temperature
of 400° C. — Comptes rendus , cxxiv., 898.
Dupont and Guerlain have investigated the
Basilieum oil of Ocymum basilieum, L., which does not
Oil. appear to have been examined previously,
except that Dumas and Peligot isolated from it
an odourless crystalline body to which they attributed the formula
C10H2/)3. The essential oil reported on by the authors was a
somewhat oily fluid, yellowish in colour, with a peculiar powerful
and characteristic odour ; its specific gravity was at 15° C. , 0"9154, and
its rotation for 100 Mm. - — 7°40'. At ordinary pressure 80 per cent,
of the oil distilled between 190° and 220°. On refractionation the
greater part, equivalent to about 60 per cent, of the essence, dis¬
tilled between 195° and 200° C., and had the odour of linalool.
Its optical rotation was — 12°, and its gravity 08552, its index of
molecular refraction and other characters were those for laevogyre
linalool ; a higher fraction boiling between 205-215 had an odour
resembling estragol from tarragon oil ; its rotation was — 6°40'. It
was proved to be estragol by converting it into its propenylic
isomer, anethol. The two chief constituents, of basilieum oil are,
therefore, linalool and estragol. — Journ. de Pharm. [6], 1., 453.
A. H. Hills describes the wood of Jamaica
Characteristics quassia ( Picraena excelsa) as being distinguished
Of by the medullary rays being mostly three cells
Quassia. in width, the cells irregular in size and their
radial walls regular in tangential sections.
Surinam quassia {Quassia amara ), on the other hand, has medullary
rays generally only one cell in width, the cells composing the rays
being nearly uniform in size, whilst their radial walls appear wavy
in tangential sections. The characteristics of powdered quassia
are also given, but as the drug is practically never seen in powder
in this country it appears unnecessary to give them here. — Journal
of Pharmacology, iv. , 116.
Comparison of the relative percentages of
alkaloids and of gelsemic acid in the rhizome,
roots and stem of commercial gelsemium have
been made by Sayre. He finds that the active
principles of the plant are absent or only
present in very minute quantity in the stems,
the relative proportions per cent, being —
Rhizome. Roots. Stem.
Volatile Oil . . 0-5 . . .
Fixed Oil . . . . 5-7 ...
Resins . 4 -4 ...
Alkaloid . 0-2 ...
Gelsemic Acid . 0 37 . . .
Other Organic Acids .... 2 "7 ...
• — Amer. Joum. Pharm., lxix., 234.
Active
Principles
in
Gelsemium.
0"4 . trace
7-4 . 3-2
2 4 ...... 3-8
0-17 ...... —
0-3 —
2-8 1-9
Coblentz controverts Robbins’ statement that
Gelsemic Acid, gelsemic acid is identical with tesculin. He
points out that the melting-points of the two
bodies and of their acetyl and bromo-derivatives are quite different.
Gelsemic acid melts at 205 -5° to 206° C., its acetyl compound at-
180° C., and its bromo-derivative at 250°. The figures for aesculin
are 160° C., and for its corresponding acetyl compound 130° C., and
for bromo-aisculin 193° to 195°. He states that the formula found
by Robbins is incorrect, and attributes the error to incomplete
combustion. Gelsemic acid, unless special precautions are taken,
is not completely burnt, part of the carbon condensing to a
graphitic condition in the tube. — Am. Journ. Pharm., lxix., 229.
C. Pfister shows that the pollen grains of
herbs collected with the flowering tops are so-
characteristic in shape, whilst varying but little
in size, that they serve as a useful means of
distinguishing powders prepared from the
herbs. The pollens were obtained for examination by breaking
open the anthers of the flowers, and then mounted in sweet almond
oil, the cover glasses being ringed with gold size. The varieties
pictured and described are classified into three groups : 1. Pollen
bounded by smooth outline — Gataria, Marrubium, Artemisia, Ab¬
sinthium, Lobelia, Pulsatilla, Scoparius ; 2. Echinate pollen,
rough, with minute spines — Tanacetum, Mentha piperita, Grindelia
robusta, Eupatorium, Hedeoma, Chiretta ; 3. Pollen with undulate
surfaces — Mentha viridis. — Journal of Pharmacology, iv., 113.
From a series" of experiments carried out
Influence Of Light on a variety of different plants, Herr K.
on the Growth Stameroff obtains the following results.
Of Plants. The vegetative hyphse of Mucor and Sapro *
legnia grow with equal rapidity in light and
in darkness, but light has a depressing effect on the growth of the
reproductive hyphse of Mucor. The rhizoids on the bulbils of
Marchantia polymorpha grow more slowly in the light than in the
dark. Light produces no effect on the rapidity of growth of the
pollen-tubes of Colutea arborescens and Robinia pseud-acacia. —
Flora, 1897, p. 135.
Herr F. Oltmanns states that there is for
Positive and every species of plant an optimum intensity of
Negative light for heliotropic sensitiveness. In the case
Heliotropism. of the fructification of Phycomyces he found the
curvature to benegative, indifferent, or positive,
according to the distance from the source of light, the former
being the case with small, the latter with great distances. Green
seedlings of barley are more sensitive to light than etiolated ones.
The horizontal position of many stems and aerial stolons is the
result of geotropism rather than of heliotropism. — Flora, 1897, p. 1.
Herr J. Schniewind-Thies describes the nec-
Septal taries seated in the septa of the ovary which
Nectaries. are peculiar to certain orders belonging to the
Liliiflorae and Scitaminese. The simplest form
occurs in Tofieldia palustris, where the nectar is excreted from
the entire outer wall of the ovary, while in T. caly-
culata the secretion is limited to the furrows in the
wall of the ovary which correspond to the septa. The
nuclei of the secreting tissue are distinguished from those of the
parenchyme by the large amount of chromatin contained in them,
and usually by the greater abundance of nucleoles. In most of
the nectaries the nuclei are erythrophilous. In Leucojum vernum
the nectaries are found in the apex of the style ; in Galanthus nivalis
in the summit of the ovary ; on the ovary of the Zingiberaceai they
are excrescences of a club shape or some other form. — Beitrdge zur
Kenntniss der Septal-nektarien, Jena, 1897.
Study
of
Pollens.
468
PHARMACEUTICAL JOURNAL.
[May 29, 1897
Professor R. Chodat traces back all the
Evolution principal groups of chlorophyllous algae to the
Of the Palmellaceas, comprising the genera Palmella,
Green Algse. Tetraspora, GMocystis, and Apiocystis. In
them cell-division may take place in three
different ways: Irregularly in all directions [Palmella- condition), in
one plane only ( Tetraspora- condition), or tetrahedrally [Glceocystis-
condition). From these three principal conditions arise three lines
of descent : (1) the Volvocinese, (2) the Pleurococcoidese, and (3)
the Ulvacese and the filamentous green algae. The Volvocinese^are
derived immediately from the unicellular species of Ghlamf-
domonas. Nearly allied to them is Gonium, where the tetra-
sporoid condition is motile. All the genera of Protococcoideae
( Oocystis, Nephrocytium, Scenedesmus, . Raphidium, etc. ) can be ,
reduced to globular unicellular colonies. The Pediastreae ( Pedi -
astrum, Gcelastrum, Sorastrum, Hydrodictyon, etc.) constitute a
parallel group. The Ulvaceae and Chaetophoracese are united with
the simplest forms through Pleurococcus and Monostroma. The
highest development of the filamentous green algae is reached in
the Coleochaeteae. — Annals of Botany, 1897, p. 97.
M. A. Lendner records the results of a
Influence Of series of experiments on the effect of the
External conditions access and withdrawal of light on a variety
On the Development of fungi, chiefly Mucorini and Ascomycetes,
Of Fungi. grown on different media. All the
Mucorini examined developed sporanges
under the influence of light when grown on solid substrata ; in
liquid media the results varied with the species. In the case of
the conidial forms of the Ascomycetes, conids w'ere invariably
formed under the influence of alternate day and night ; under
continuous light the results varied with the species. All the
phenomena of heliotropic sensitiveness in fungi appear to have
their source in the need for nutrition.— A nn. des Sciences Nat.
Botanique, 1897, p. 1.
F. Nobbe and L. Hiltner have carried on a
Inoculation Of series of experiments on the inoculation of
Nodule Bacteria the bacteroids from the root-tubercles of one
in Different species of leguminous plant to those of a
Host-Species. different species. The results were mostly
negative, the inoculation being certain only
from one plant to another of the same species. The Viciese afford
an exception, inoculation being in them possible from one species
to another without any essentially lessened effect. They found
the result of inoculation to be increased vigour, especially in the
production of flower and fruit, and this was observed particularly
in peas and red clover. The root-tubercles have no marked
influence on the growth of the aerial parts of the plant so long as
the soil contains a sufficient supply of nitrogen. — Landwirth-
schaftliche Versuchs-Stationen, xlvii., p. 257.
M. L. Planchon offers a mechanical explana-
Opening of the tion of the remarkable phenomena attending
Flowers of the sudden opening of the flowers of various
(Enothera. species of (Enothera in the evening. At sunset
the afflux of sap and decrease of transpiration
cause a general swelling of the bud, and especially of the petals.
By their swelling the petal's detach the calyx, and the reflex of
the sepals is the result of the extension of their upper surface in
consequence of a special anatomical arrangement. The opening
and unfolding of the petals is then effected by a further swelling
of their lamina accompanied by enlargement of the disk. The fall
of the flower the next morning is the result of the dissociation of
the cells which unite the calycine tube with the ovary. — Bull. Soc.
Bot. de France, vol. xliii. , 455.
Professor W. Zopf gives a detailed account
ParasymbiOSiS of the fungi which grow on different species
Of Fungi. of lichens, numbering 344 species belonging
to 76 genera. These fungi are not in all
cases true parasites, but have a kind of symbiotic relationship
to the lichen-host which he terms parasymbiosis. The hyphas of
the “parasite” completely envelope the algal constituent of the
lichen without inflicting any injury upon it. Observations are
recorded especially on Rhymbocarpus punctiformis growing on
Rhizocarpon geographicum, and on Gonida punctella and G. rubescens
growing on Diplotomma alboatrum. The hyphse of the parasite
may be clearly distinguished from those of the lichen by their
chemical reactions, the latter being coloured a beautiful blue by
iodine solution, wjiile the former are not. — Hedwigia, 1896, p. 312,
and Ber. Deutsch. Bot. Gesell., 1897, p. 90.
M. C. Candolle continues his researches on
Latent Life the powder of seeds to maintain their vitality
Of under low temperatures. He states that seeds
Seeds. of Indian corn, oat, fennel, Mimosa pudica,
Gloxinia, and other plants, when exposed for
118 days to a temperature of -40° F., will, in most cases, still
germinate. The protoplasm of the seeds he regards as not actually
in a living state, but as having entered a stage of inaction in
which, though to all appearance dead, it is still endowed with
potential life. — Report Liverpool Meeting Brit. Ass., 1896.
The bushmen of the South African district
Arrow Poison “Kalahari” use the juice of the leaf beetle
from “ Diamphidia” and its larva for poisoning their
Larvae. arrow-heads. Lewin (who calls the beetle
Diamphidia simplex, Per.) found in its body,
besides inert fatty acids, a toxalbumin which causes paralysis and
finally death. According to Boehm, the poison from the larva
also belongs to the toxalbumins, and Starke states that it causes
the dissolution of the colouring matter of the blood and produces
inflammation. To obtain a solution of the poison, Boehm recom¬
mends the maceration of the whole larva with distilled water. After
some hours they swell up and the solution becomes light yellow
coloured and is acid in reaction. This reaction still remains after
shaking out with ether. The aqueous solution then has poisonous
properties. The action of the poison is destroyed by boiling. It
gives the usual reactions of a toxalbumin, and may be precipitated
from its aqueous solution by means of sulphate of ammonia. —
Pharm. Central., xxxviii. , 277.
This is a fibrous material of serpentinous
AsbestiC. origin, which remains after the richer veins
of asbestos have been extracted from the rock
containing it. According to R. H. Jones, it can be converted into
a fireproof plaster, which is also a non-conductor of heat and
sound. It is odourless, elastic, and vermin-proof, forms a natural
filter, and will adhere well to metal or glass. Paper of superior
quality is made from it, in place of wood, straw, or other pulp. —
Journ. Soc. Arts, xlv., 544.
Lannelongue and Achard record some
Gallinaceous Birds curious facts with regard to the immunity
and of fowls to the action of the human tubercle
Tuberculosis. bacillus. As the result of their experi¬
ments it would seem that although the
bacilli when introduced into the body of fowls, retain their viru¬
lence for guinea-pigs, they appear while in the bird’s body to lose
their power of generation, and do not increase in number. They
become encysted, not because the secretions of the bird’s blood is
fatal to them, but merely because they have no power of reproduc¬
tion. The blood and body secretions of fowls, per se, have no
May 29, 1897]
PHARMACEUTICAL JOURNAL.
469
inhibitory action on the bacilli when employed as an antitoxin,
in the case of guinea-pigs inoculated with tubercle, either before or
after the bacilli have been introduced into the bird’s body. The
resistance of fowls to human tuberculosis is, however, only partial,
since they may eventually be affected by the necrotic substances
contained in the bodies of the bacilli. — Gomptes rendus, cxxiv., 886.
Dr. Winter Blyth is convinced that formic
Disinfection aldehyde gas is superior to sulphurous acid gas
with as a disinfectant, and he recommends its use to
Formic the Vestry of St. Marylebone accordingly. In
Aldehyde. a comparative trial pieces of linen on which
were cultures of the bacilli of diphtheria,
typhoid, anthrax, and tuberculosis were exposed to the two gases
in separate rooms for nineteen hours. Subsequent examination of
the infected pieces of linen by Professor Macfadyen showed the
following results : —
Organism.
Sulphurous acid.
Formic aldehyde.
Diphtheria bacillus .
No growth
N o growth
Typhoid bacillus . . . .
Good growth
No growth
Anthrax bacillus . .
Good growth
No growth
Contamination with other organisms prevented the tubercle
samples being properly reported on.
C. A. Whitmore sets himself to disprove the
Weather Signs popular notion that the moon exercises some
and influence upon our climatic conditions, its
Fallacies. changes synchronising with marked changes
in the weather, and quotes facts in connection
with the weather of the past twelve months, which should con¬
vince people who misplace faith in the influence of the earth’s
satellite. He deals also with other weather fallacies, showing that
a heavy dew at night is not a sign of stable weather, but simply
indicates that the sky is clear and the conditions favourable for
the deposition of dew, whilst with regard to the old-time notion
that a luxuriant crop of berries foretells a hard winter, he suggests
that it implies no more than the fact that the past season has been
favourable to the production of berries. — National Review, May, 1 897.
A. E. Munby points out that the cheap pro-
Bunscn Burner duction of calcium carbide has placed a power -
fOP ful illuminant within the reach of those who
Acetylene. possess no gas supply, but so far little has been
heard of the use of acetylene as a heating
agent. He employs a Bunsen burner of special dimensions, the
tube being 5 millimetres in internal diameter. A slightly wider
tube may be used, provided the mouth be curved inwards, so that
the actual exit does not exceed the diameter mentioned ; if larger,
the flame tends to strike down. The gas jet is very small, being
only capable of delivering about 1 cubic foot of acetylene per
hour under 6 inches water pressure, such a rate of consump¬
tion giving an ordinary working flame. The air-holes and
collar are arranged as in an ordinary Bunsen, the exact
size of the holes not being of much importance, provided
they be large enough to admit the air required. The burner
is protected with a cap, when not in use, as its efficiency
depends upon the jet maintaining its dimensions. A generator
capable of giving gas under seven inches water pressure with the
full number of burners in use is required. Under this pressure a
large, perfectly blue flame is obtained, which may be turned down
to what may be termed a quarter Bunsen flame, equivalent to
burning the gas under three to four inches water pressure. This
is the smallest pressure with which the burner will give a non-
luminous flame ; when turned lower, the zone of partial combustion
appears, since the draught is then insufficient. The heating effect
of the flame is, of course, very great, enabling one to dispense
with the blow-pipe for such operations as small fusions. From a
few experiments on heating equal quantities of water under like
conditions with coal gas andacetylene, it would seem thatin practice,
for equal volumes burnt, the latter has nearly twice the heating
power of the former.— Proc. Ghem. Soc,, 179, 103.
The use of the microbes of chicken cholera
Rabbits is, after all, likely to be resorted to in
and dealing with the rabbit pest in New South
Microbes. Wales. When this plan was originally sug¬
gested by Pasteur reluctance was felt to
introduce a new disease into the Colony. But the Govern¬
ment bacteriologist has recently shown that chicken cholera
does exist both in New South Wales and Queensland, and
he describes in detail various scientific investigations, the results-
of which place the matter beyond doubt. Extensive experiments,
prove the efficacy of this method of destroying rabbits to be very
great, and the Government has therefore been recommended to-
grant permission to persons who suffer from the depredations of
the animals to utilise this novel means of suppressing them. It
has been calculated that two gallons of broth infected with chicken
cholera microbes is sufficient to destroy at least 20,000 rabbits,
irrespective of infection induced by contagion. — Nature, lvi., 16.
Professor Villari states that gases appear to
Gases as be improved as heat conductors after being
Heat traversed by electric sparks, the apparent
Conductors. cooling producing a fall of resistance of 10 per
cent, in some cases. He records a number of
experiments in which the sparks were produced by a powerful
coil, supplemented by large Leyden jars. After the gases had
been traversed by the sparks, they were allowed to act upon a
platinum spiral heated to redness by an electric current. Under
similar conditions, oxygen, nitrogen, and air were practically alike
in their cooling effects, but that of hydrogen was much less marked.
The cooling effect of the gases increased with that of the energy
of the sparks, and also, at first, with the temperature of the
platinum spiral ; but after the latter exceeded a certain limit the
refrigerating power decreased. — Nature, lvi., 15.
Sabrazes and Riviere find that the X rays are
Action absolutely without action on the growth and
Of pigmentation of cultures of Microbacillus
X Rays. prodigiosus, even when the bacilli were exposed
to their influence for twenty days. In a like-
manner the leucocytes of the blood of a living frog were not
affected in any way, nor was their phagocytosis perceptibly
modified in any way. It has been stated that Rontgen’s rays have
affected the heart when patients have been exposed to their
influence. The authors find, however, that when the heart of a
living frog is placed under an intense source of the X rays the
rhythm of that organ is in no way affected even after an exposure
of more than an hour’s duration. It would seem, therefore, that
the X rays are biologically inert. Professor W. Crookes also con¬
firms the statement that the X rays act upon the skin of certain per¬
sons with varying intensity, but he believes that the effects are
largely due to personal idiosyncrasy. Although he has himself
worked with the tubes producing these rays for a longer time
probably than any other experimenter, without perceiving the
least effect upon the face or hands, he has seen marked action
produced on the skin of others who have been exposed to the rays
for a markedly shorter time. — Gomptes rendus, cxxiv., 855 and 979.
470
PHARMACEUTICAL JOURNAL.
[May 29, 1897
HISTOLOGY OF THE VEGETABLE TISSUE SYSTEMS.*
BY DR. J. LOUIS D. MORISON.
The several tissues that compose the bodies of plants are not
found in the root, stem and leaf without definite order, but are
grouped into systems for the performance of different kinds of
work. In all the higher plants, at least, three principal systems
may be distinguished. These are the epidermal or boundary
tissue system, the fundamental or ground tissue system, and the
fibro-vascular or conducting tissue system.
Development of the Tissue Systems. — In the higher plants these
three systems of tissue originate from meristem cells located at the
growing-point of the stem and root.
In the growing-point these embryonic cells very soon become
differentiated into three primary meristem layers known as
dermatogen, periblem, and plerome, from which are developed,
respectively, the epidermis, the primary cortex, and the stele or
vascular cylinder. The dermatogen forms the outermost layer of
cells at the growing-point, and when present always develops into
true epidermal tissue. In stems the dermatogen is always single¬
layered, while in roots it consists of several layers and develops a
many-layered epidermis. As the root grows older the cells of this
many-layered epidermis are gradually exfoliated, persisting only
at the apex, where they form a many-layered root-cap. Above the
root-tips the epidermal cells either all disappear but the inner
layer (dicotyls), or disappear altogether (monocotyls), leaving the
functions of the epidermis to be performed by the outer layer of
the primary cortex.
The periblem occurs immediately beneath the dermatogen,
forming a hollow cylinder of tissue, which surrounds the plerome.
From the periblem is developed the fundamental tissue of the
primary cortex. When no dermatogen is present in the growing-
point (stems of vascular cryptogams) the external layer of the
periblem develops cells which perform epidermal functions.
The plerome occupies the centre of the growing-point, and con¬
sists of a solid mass of somewhat elongated cells. From the plerome
are developed the fibro-vascular and fundamental tissues of the
vascular-cylinder or stele. Usually but a single stele is developed
from the plerome (monostelic organs), but sometimes two or more
are formed, each stele either developing from separate plerome-
strands (polystelic organs), or are formed by the splitting of an
original stele derived from a single plerome (schizostelic organs).
Epidermal or Boundary Tissue System. — This system constitutes
the external covering of the body of the plant, and is commonly
called the epidermis. It includes, besides the ordinary epidermal
cells, the guard-cells of the stomata and water-pores, the plant-
hairs or trichomes, and the epidermal or external glands. The
epidermal tissues are chiefly protective in function, serving to
prevent excessive evaporation from the interior tissues of the plant.
In stems the external layer of cells, whatever its origin, is known
as the epidermis, while in roots it is called the epiblema. The
epidermis usually consists of a single layer of cells, but in some
cases it is two or three-layered, as in the leaves of figs and begonias.
The epiblema is also usually single-layered, but occasionally con¬
sists of many layers of cells, as in the roots of some epiphytic
orchids, where the many-layered epiblema is known as the relamen.
In land plants the epidermis is usually strongly cutinised, while
in submerged aquatics it is never cutinised. The epidermis of
land plants is also often waxy, the wax occurring on the surface
as minute grains, rods or flakes, constituting the so-called bloom
of leaves and fruits, and giving to them their glaucous appearance.
Chlorophyll bodies are usually absent from the ordinary epidermal
cells of land plants, while they commonly occur in the epidermal
cells of aquatic plants.
Ordinary epidermal cells are usually thin-walled and transparent,
and contain a nucleus and colourless watery protoplasm, but are
destitute of both chlorophyll-bodies and starch-grains.
The external layers of the outer walls are usually strongly
cutinised, constituting the so-called cuticle of the plant, while the
internal layers and the radial and inner walls are composed of
cellulose. The cells of the epidermis are always very compactly
arranged, having their walls so closely adherent that the inter¬
cellular spaces are entirely obliterated except at the stomata and
water-pores. In surface view epidermal cells are usually wavy or
irregular in outline, but are sometimes more or less regular, having
straight sides and squarish ends. In very many cases they are
* Address delivered to Beta Phi Society of the Philadelphia College, of Phar¬
macy. Prom the Alianni 'Report.
elongated in the direction of the organ which bears them, when
they are apt to be oblique-ended or fusiform.
The epidermal system includes, besides the ordinary epidermal
cells just described, other tissues, as the guard-cells of the stomata
and water-pores, the plant-hairs or trichomes, and the external or
epidermal glands, all of which are but modifications of ordinary
epidermal tissue.
The Stomata or Breathing -Pores — These are apertures in
the epidermis which lie over large intercellular spaces. They
are usually bordered by two modified epidermal cells, called
guard-cells. Stomata are formed in the following manner : A
young epidermal cell divides into two equal portions by the forma¬
tion of a septum across its middle, each half developing into a
guard-cell ; the septum now splits lengthwise and separates the
guard-cells, leaving an aperture or stoma between them.
In the higher plants the guard-cells of the stomata are crescent¬
shaped and occur in pairs, the concave sides of the cells facing
each other with the aperture between, while in mosses the stomata
possess but a single annular guard-cell which surrounds the
aperture. The guard-cells of stomata usually contain chlorophyll-
bodies in addition to the ordinary protoplasm. They have the
power of increasing or diminishing the size of the aperture under
the influence of light and moisture, and thus regulate the amount
pf evaporation from the interior tissues of the plant.
Stomata are confined to the sporophyte-plant, occurring on the
stems and leaves, but absent from the roots and from submerged
parts. They are most abundant on the lower (dorsal) surface of
dorsi-ventral leaves, but are about equally distributed over both
surfaces of iso-bilateral and centric leaves. In floating leaves they
occur on the upper epidermis only.
Water -Pores or Water -Stomata. — These are also apertures in the
epidermis, similar in structure to ordinary stomata, but differ from
them both in function and distribution. Water-pores excrete
water in the form of drops, and have their guard-cells fixed and
immovable. They always occur at the ends of vasal bundles, and
are found on the margin and at the apex of leaves.
Plant-hairs or Trichomes. — There are modified epidermal cells
which have become prolonged externally, and may be either
unicellular or multicellular. Each hair consists of a basal portion,
or foot, which is embedded among the ordinary epidermal cells,
and an apical portion, or body, which is prolonged externally.
Ordinary epidermal hairs are usually thin-walled, the inner layers
of the wall being composed of cellulose, while the outer layer is
more or less strongly cutinised. Sometimes the walls become
hardened by deposits of lime-salts or silica.
When young, the cells contain both protoplasm and nucleus, but
as they mature, their protoplasmic contents disappear and are
replaced by air. Sometimes the cells become glandular and
secrete oily, resinous or other matters, when they are known as
glandular hairs.
The root-hairs spring from the epiblema, and the part of the
latter which bears the hairs is known as the piliferous layer. The
walls of root-hairs are never cutinised, but are frequently more or
less mucilaginous. The root-hairs are the principal absorbing
organs of the plant, and are confined to the younger roots, occur¬
ring just above their tips. Root-hairs are never present in
aquatic plants, and are absent from the roots of some of the
Conifer®.
Fundamental or Ground Tissue System. — This system constitutes
the groundwork of the plant, and is the system through which the
vasal bundles are distributed. The fundamental tissues are
composed largely, though not wholly, of ordinary parenchyma,
and are chiefly concerned in the metabolic work of the plant.
Ground tissue includes, besides ordinary parenchyma, collen-
chyma, sclerenchymatous parenchyma, fibrous tissue, cork or
suberous tissue, laticiferous and glandular tissues. To the
fundamental system belongs the green-cells of leaves, the thin-
walled cells of the pith and medullary rays, the cells of the cortex
of stems and roots, and most of the soft cellular tissues in all
plants.
The lower plants consist almost entirely of fundamental tissue.
In the herbaceous forms of the higher plants the ground tissues
largely predominate, while in woody plants they are present in
much smaller proportion, the vascular tissues being the most
abundant. In aquatic plants generally, the fundamental tissues
constitute the principal system. According to its relation
to the stele or steles, the fundamental- tissues may be divided
into extra-stelar and intra-stelar ground tissue, the former
Mat 29, 1897J
PHARMACEUTICAL JOURNAL
471
developing from the periblem, the latter from the plerome, in the
growing-point.
The extra-stelar fundamental tissues include all the ground
tissue outside the stele or steles. It is bounded externally by the
epidermis, and internally by the stele or steles. In monostelic
organs the extra-stelar tissues consist of several or many layers of
cells, and constitute the so-called cortex of stems and roots. In
polystelic and schizostelic organs the extra-stelar tissues include
not only the tissues of the cortex, but also the ground tissue
between and among the steles, which is sometimes spoken of as
inter-stelar tissue. The extra-stelar tissues may usually be
distinguished into three distinct layers, namely, the hypoderma,
the general ground tissue, and the endodermis.
The hypoderma occurs immediately beneath the epidermis, and
consists of several or many layers of cells. It may be composed
of eollenchyma or sclerenchyma, but in a few cases it consists of
aqueous tissue.
A collenchymatous hypoderma is found in the stems and petioles
of most herbaceous dicotyls, and frequently occurs next the mid-rib
of leaves, where it forms a strengthening tissue. A sclerenchy-
matous hypoderma occurs either as a continuous layer beneath the
epidermis, as in the stems of some ferns, as Pteris aquilina, and
some leaves, as those of pine ; or, it may form numerous isolated
strands beneath the epidermis, as in the stems of horsetails and
some Umbelliferse.
A hypoderma of aqueous tissue occurs in the leaves of some
monocotyls. It is composed of thin-walled parenchymatous cells
that are closely packed together without intercellular spaces. The
cells of this tissue are usually filled with an abundance of watery
sap, and thus serve as reservoirs for water.
The hypoderma of the root is known as the exodermis, and
forms the second layer of the cortex, the outer layer being the
epiblema, which bears the root-hairs. The walls of exodermal
cells are usually cutinised and thickened, the thickening occurring
on the upper, lower, and lateral walls of the cells.
In monocotyls the exodermis persists throughout the life of the
root, while in dicotyls it very soon disappears, being replaced by
cork or periderm formed immediately beneath it.
The general ground tissues lie within the hypoderma, and con¬
sist of several or many layers of cells. They are composed
principally of ordinary parenchyma, but may contain, in addition,
either stone cells, sclerenchyma fibres, laticiferous or glandular
tissues. Between the cells of the general ground tissues are
usually found rather large intercellular spaces. These, for the
most part, are schizogenous in origin, being formed by the split¬
ting apart of contiguous cells.
The endodermis is the innermost layer of the extra-stelar funda¬
mental tissues, and always abuts on the stele or steles. In mono¬
cotyls it marks the boundary between the cortex and the central
cylinder, and it is sometimes spoken of as the nucleus sheath.
The endodermis usually consists of a single layer of cells, but in
a few cases it is two-layered. In stems the endodermal cells are
usually thin-walled and unlignified, having a suberous thickening
band extending round the upper, lower and lateral surfaces, which
in cross-section appears as a black dot on the radial wall. Some¬
times this suberous thickening is wanting, when the endodermis
may be distinguished by the fact that the cells are filled with an
abundance of starch-grains. In roots the endodermis is generally
thickened and lignified, the thickening occurring either uniformly
over the whole surface of the cell, or, more commonly, it is confined
to the radial and inner walls. When the endodermis thus becomes
thick-walled, some of the cells remain thin and unlignified, and are
known as passage cells.
The intra-stelar fundamental tissues include all the ground tissue
within the stele, and is sometimes spoken of as conjunctive tissue.
When the stele develops but a single vasal bundle, it may contain
no ground tissue at all, but more commonly fundamental tissue is
developed, along with the vasal bundles from the plerome. ,
According to its position in the stele, the conjunctive tissues
may be distinguished into three principal portions, viz., that
portion which invests the vasal bundles, the pericycle ; that
portion which lies between the bundles of the stele, the inter¬
fascicular conjunctive tissue ; and that portion which occupies the
centre of the stele, the medullary conjunctive tissue. The peri-
cycle, formerly called the pericambium, is the outermost layer of
the conjunctive tissue of the stele. It occurs immediately
beneath the endodermis, and forms a continuous covering over the
vascular tissues of the stele. The pericycle is rarely absent, but
when wanting, the endodermis is always two-layered.
In roots the pericycle always consists of a single layer of cells,
while in stems it may be several or many-layered. The cells of the
pericycle are usually parenchymatous, being thin- walled, and
possessing protoplasmic contents ; but in some cases they are
sclerenchymatous, being thick-walled and lignified. Sometimes
the pericycle becomes meristematic, and may give rise to secon¬
dary formations of cork, or of vascular tissue. In phanerogams
the root-branches originate in the cells of the pericycle. Some¬
times the pericycle is absent, as in the roots of some aquatic
plants, in which case the vasal bundles lie directly in contact with
the endodermis.
The interfascicular conjunctive tissue lies between the bundles
of the stele, and consists for the most part of parenchymatous
cells. Sometimes the interfascicular tissues become sclerenchy¬
matous, where they abut on the vasal bundles, as in many mouo-
cotyl stems. In dicotyls and gymnosperms the medullary rays
consist essentially of interfascicular ground tissue.
The medullary conjunctive tissue occupies the centre of the
stele, constituting the so-called pith. It usually consists of paren¬
chymatous cells, but may contain, in addition, either stone cells,
sclerenchyma fibres, laticiferous or glandular tissues.
Sometimes large intercellular air spaces are found in the pith of
plants. These are generally lysigenous in origin, being formed by
rupture and destruction of cells, as in the stems of grasses, horse¬
tails, and the Umbelliferse.
The Fibro-vascidar or Conducting Tissue System. — This system
constitutes the fibrous framework of the plant, and is the system
by means of which fluids are conducted from one part of the plant
to another. Its function is partly to give strength and support,,
but principally to conduct the crude and elaborated juices to and
from the leaves. It is found only in the higher plants, consti¬
tuting the tough and stringy tissues in stems and roots, and the
system of veins in leaves. The fibro-vascular system consists
essentially of vascular tissue (ducts, tracheids, and sieve-tubes),
and forms long strands — the fibro-vascular bundles — which
extend vertically through the fundamental tissues of the plant.
The term “ fibro-vascular,” as applied to the conducting system,
is not strictly correct, since fibres do not always accompany the
vascular elements, hence this system is often spoken of as the
vascular system, and the bundles as vascular, or more briefly as
vasal bundles.
The Vasal Bundles. — Every complete vasal bundle consists of
two parts, the xylem or wood, and the phloem or bast ; and as
these two parts are joined in a single strand, they are often*
spoken of as conjoint bundles.
Incomplete bundles may consist either of xylem or of phloem when
they are spoken of as xylem bundles, and phloem bundles respec¬
tively.
The xylem or wood consists essentially of trachery tissue (ducts •
and tracheids), but may contain in addition both wood fibres and
wood parenchyma. In herbaceous plants it may consist entirely
of vascular tissue, while in woody plants the ducts and tracheids-
are nearly always accompanied by wood fibres and some wood
parenchyma. The phloem or bast consists essentially of sieve
tissue (sieve-tubes, with or without companion-cells). It usually
contains some ordinary parenchyma, and hard bast fibres may or
may not be present. In angiosperms companion-cells always
accompany the sieve-tubes in the phloem, while in gymnosperms
they are absent.
Between the xylem and phloem portions of a conjoint bundle, a
thin layer of meristem is sometimes present. When this is the
case, the bundle is said to be open, since it continues to enlarge
by additions of new wood and new bast to the already formed
elements. If, however, no meristem is present, the bundle is said
to be closed, as no growth takes place after it is once fully formed.
Complete or Conjoint Bundles. — According to the relative positions
of the xylem and phloem elements, there are two principal kinds
of conjoint bundles — the collateral and the concentric.
In collateral bundles, the xylem and phloem tissues are always
placed side by side. Of these there are three varieties, viz., the
open collateral, the closed collateral, and the bi-collateral. In the
open collateral bundle meristem tissue is always present between
the xylem and phloem elements. These bundles are usually more
or less wedge-shaped, the xylem occupying the inner or narrow
end of the wedge, while the phloem is placed at the outer or broad
end.
Open collateral bundles occur in the stems of most dicotyls and
gymnosperms, and are also found in the roots of these plants after
the secondary changes have taken place.
472
PHARMACEUTICAL JOURNAL.
[May 29, 1897
In the closed collateral bundle there is never any meristem
present between the xylem and phloem tissues. These bundles
are never so distinctly wedge-shaped as are those of the open
variety, and, as in open collateral bundles, the xylem tissues are
always directed toward the centre of the stem, while the phloem
faces the periphery.
Sometimes these bundles are enclosed by a sheath of scleren-
chyma fibres, which, however, forms no part of the bundle itself,
but belongs to the interfascicular ground tissues outside the
bundle.
Closed collateral bundles occur in the stems of most monocotyls.
They are also found in the stems of Equisetum, and occur in nearly
all leaves. In the bi-collateral bundle there is a single xylem, but
two phloem portions, the xylem tissues lying between the two
masses of phloem. These bundles always have a layer of meristem
between the xylem and one or both phloem masses, so that they
may he open on one or both sides of the bundle.
Bi-collateral bundles occur only in the stems of a few families of
the higher plants, such as the Cucurbitaceae, Myrtacese, Poly-
gonaceaa, Apocynaceee, and some Convolvulaceae.
In concentric bundles one of the elements, either the xylem or
the phloem, occupies the centre, and is more or less surrounded by
the other. Meristem tissue is never present, hence concentric
bundles are always closed.
Concentric bundles with a central xylem occur in the stems
of most ferns. They are always surrounded by a pericycle and
endodermis, and are best regarded as steles. Concentric bundles
with a central phloem occur in the rhizomes of some monocotyls,
as calamus, iris, smilacina, convallaria, etc. Bundles of this type
never possess either pericycle or endodermis.
Sometimes the xylem tissues do not entirely surround the
phloem, in which case the bundle might be regarded as a closed
collateral bundle in which the ducts have grown round, but not
quite enclosed the sieve-tissues.
Incomplete or Separate Xylem and Phloem Bundles. — These were
formerly regarded as together forming a single bundle, and as such
was described as a radial bundle. They are now considered to be
separate strands or bundles of xylem and phloem tissue, only
radially arranged, and alternating the one with the other. The
individual bundles are always separated by interfascicular ground
tissue, and there are as many bundles of one kind as of the other.
Sometimes the xylem bundles become fused together at the centre
and form a few or many-rayed, star-shaped mass. This collection
of bundles is always surrounded by both pericycle and endodermis,
and is, in fact, a stele.
Separate xylem and phloem bundles — the so-called radial bundle
—occur primarily in all roots, and are also found in the stems of
Lycopodium.
The Stele or Vascular Cylinder. — The vascular cylinder or stele
is developed from the plerome of the growing-point, and consists
of one or more vasal bundles imbedded in fundamental tissue, the
whole being enclosed by a pericycle and an endodermis. It usually
contains both fundamental and fibro-vascular tissue, but may
contain, in addition, either glandular or laticiferous tissue.
The typical stele, therefore, includes all the tissues evolved by
the endodermis, which, however, forms no part of the vascular
cylinder itself, but merely surrounds it. The pericycle is always
the outermost layer of the tissues of the stele, while the endodermis
is the innermost layer of the extra stelar tissues.
Value of Cytisine in Medicine. — Plugge calls attention to the
alkaloid of the cytisus as being worthy of an extended trial in
therapeutics. It causes contraction of the arterioles, and a
consequent rise of blood pressure. It has been recommended as a
diuretic, and to relieve the hypersemia of acute arsenical poison¬
ing, and again for melancholia and paralytic migraine. Owing to
its great toxicity not more than one-seventh of a grain of the
nitrate should be given hypodermically, and it is well to begin
with only one-twentieth to one-thirteenth of a grain. Plugge has
found that several plants which have a great local reputation as
medicines contain this alkaloid. Such are Sophora tomentosa
whose seeds and roots were long known in India as “ semina et
radix anticholericse,” and were used for haemorrhages, colic, and
dysentery ; Euch-sesta horsfieldii, which has a great reputation
among the natives of Java in haemoptysis and diseases of the
lungs, and Baptisia tinctoria, which is much used in North America.
The latter contains an alkaloid named by V. Schroeder “ bapti-
toxin. ” According to the author this last is identical with cytisine.
— Brit. Med. Journ. Epit., 1,97/71.
NOTES AND FORMULAS.
(Specially abstracted for the Pharmaceutical Journal.)
Idiosyncrasy Against Crabs.
Cases of urticaria following indulgence in shellfish, and particu¬
larly crustaceans, are not rare. Kirschberg relates his own case,
in which a sharp attack of urticaria followed indulgence in
crab ; he treated himself with warm baths and used an embroca¬
tion of a 3 per cent, spirituous solution of menthol, also observing,
of course, special diet. He advises an energetic purgation as soon
as the symptoms show themselves. — Pharm. Centralh., xxxviii., 260.
Examination of Potted Meat.
On this subject Remmlinger gives the following directions
If the bottom of the tin is raised and does not remain permanently
in position when pressed back but bounds up again, this may be
taken as indicative of the presence of living anaerobic bacteria,
which produce gas. Tins which have a fishy odour or a very
pungent, or according to some, a very insipid taste, should be
rejected. If the solder is liquid or dull it is a very suspicious sign.
Microscopical examination should be directed to the colour of the
muscles, since the action of anaerobic bacteria destroys this. —
Therap. Monats., xi., 182.
New versus Old Manure.
The question has been raised as to whether new or old
manure is better to put on land. Taking it ton for ton, new
manure has been found as effective as old, also that it
loses half its weight by keeping, besides losing some of its
nitrogen. Experiments made in Canada last year showed that
8000 lbs. of manure placed under shelter and weighed once a month
was reduced to 2600 lbs. between March and December. The
manure was at its best at the end of four months, weighing
3480 lbs. The experiments of eight years appear to show that the
action between fresh and rotted manure is equal, ton for ton. In
England, where the soil is stiff, fresh manure would perhaps be
more beneficial, as the soil is lightened by its use, but in Canada,
taking into consideration the undigested seeds in fresh manure,
the small rainfall, and the outlay in engaging men and horses for
daily carting the manure, it would certainly not be economical.—
Agricult. Journ., x., 315.
To Prevent Scale in Boilers.
Kerosene has been recommended to prevent scale in steam
boilers, both because of its cheapness and since it leaves no residue
and has no injurious effect on the iron. An injector is used so con¬
structed that the amount of kerosene which is fed into the boiler
drop by drop can be very closely regulated. — Journ. Soc. Chem.
Bid. , xvi. , 226, after Eng. and Mining J, , lxiii. , 45.
Variation in Richness of Milk.
The following experiments made from the successive milkings of
five cows at the experiment station of New York prove the difference
in richness in cream between the first milk drawn and the “strip¬
pings. ” The first pint contained less than 1 per cent, of butter
fat, viz., 0-S5 ; the second, 1 '40 ; the third, 1’68 ; the fourth, 2 05 ;
the fifth, 3‘27 ; the sixth, 265 ; the seventh, 3‘7 ; the eighth, 4 '05 ;
the ninth, 4 ’86 ; the tenth, 4-48; the eleventh, 4 ’40 ; and the
twelfth or strippings, 5 -23. The average of the whole of the milk
was 3 21, or about the contents of the sixth pint. This experiment
shows the necessity of careful milking, not only to secure the
richest milk, but to prevent the cows going dry too soon. — Agricult .
Journ., x., 331.
May 29, 1897]
PHARMACEUTICAL JOURNAL.
473
PARLIAMENTARY NOTES AND NEWS-
Mr. Lough, the member for West Islington, is very severe on
those wary Englishmen who take their alcohol in the form of non-
exciseable drinks. He has been informed, rightly or wrongly, that
British wines, cyder, and perry, containing 15 per cent, of alcohol,
may be, and are, manufactured and sold free of duty. This, he
imagines, is an injustice to those portions of the United Kingdom
where whisky forms the staple article of consumption, and he will,
therefore, on the 27th instant, ask the Chancellor of tbe Exchequer
whether any compensating immunity from duty can be granted to
the native stimulants produced in Scotland and Ireland. It will
be noticed that Mr. Lough’s sympathies are broad and do not stay
within the narrow boundaries of his constituency ; his heart bleeds
for those who do not like cyder and perry, or who despise the mere
15 per cent, of active stimulant they are reputed to contain.
As A Matter of Urgency the Committee charged with the duty
of investigating the administration and cost of the museums of the
Science and Art Department have issued an interim report calling
attention to the unprotected state of the art and other treasures at
South Kensington. It is well known that the buildings in which
a number of the most priceless objects are exhibited are con¬
structed as though fire were an unknown phenomenon. Lath, wood,
tarred canvas, and similar inflammable material forms a very
considerable portion of structures hitherto deemed adequate to
hold the best and most unique items of the nation’s collections,
and it is a matter for congratualation as well as astonishment that
no accident has yet deprived the people of their deservedly-prized
possessions. The Committee urges the immediate completion of
permanent suitable buildings, and it is hoped that no mind will be
found economical enough to oppose the recommendation or to
grudge the halfpennyworth of tar which is to save the ship.
Oaths, legal or vituperative, are open to objection on various
grounds, and Sir Walter Foster, who as a representative of medi¬
cine on the General Medical Council, ought to be able to tell the
public what to do and what to avoid, has been trying to render the
legal oath more innocuous. He asked the Attorney-General on
Friday last whether the form of oath could not be so modified as
to do away with the abominable ritual of kissing a dirty book — a
procedure inviting the spread of any amount of disease. The
Attorney-General, in reply, said he had been approached before on
the subject, but he thought perhaps the risk of infection had been
somewhat exaggerated. After all, no one is forced to kiss the
book, for, as the law officer pointed out, the Oaths Act, 1888, gives
witnesses the privilege of taking oaths in the Scots fashion, and
involves no close embrace of a microbe-bound volume. The
Attorney-General seemed, however, to recognise that very few
Englishmen are familiar with the North British mode of swearing,
and he therefore promised Sir Walter to consider whether any
further amendment of the law relating to oaths was required.
Mr. Ritchie’s promise to re-introduce the Board of Trade Bill
to legalise the metric system of weights and measures in this
country is of such ancient date that most people have forgotten it.
But he has not, and on the 27th inst. he will proceed to fulfil the
promise by bringing to the House a second time a permissive
Bill to enable British exporters to use the system of weights and
measures which obtains in every civilised country except Russia
and England. As a Government Bill, Mr. Ritchie’s protigi stands
a much better chance of reaching the statute book than a private
bill, but that after all is not saying much for it, seeing that the
Government has big things yet on hand, and the time of the House
will be curtailed by the Whitsuntide and Jubilee adjournments.
Food and Drugs. — Mr. Dillon will, on the 27th inst., ask the
first Lord of the Treasury when the Government intends to
introduce the Bill to amend the Sale of Food and Drugs Act.
Last week we chronicled a similar question by Mr. Jeffreys,
together with a not altogether satisfactory reply by Mr. Balfour.
But the prospect is distinctly brighter now that an Irish member
has undertaken to voice the dissatisfaction existing outside the
House at the delay in dealing with so important a subject.
A
PHOTOGRAPHIC NOTES-
The Anti-Cutting Movement. — The principal plate and paper
manufacturers have formed an association to keep up the retail
prices, and this has been warmly welcomed by the leading retail
dealers, but on the other hand many professionals who will not
now be able to obtain quite such a large discount are crying out
most bitterly, and there is not the slightest doubt that many of
the foreign makers of papers especially will reap some benefit
from the rise in price. That a large quantity of foreign plates
and papers are already sold in England cannot be denied, and
this movement will give the foreigners a still better chance of
gaining a firmer foothold.
Cinematographs at a Discount.— The awful fire in Paris, which
has claimed so many victims, was caused, it is stated, by the
explosion of an ether saturator used in the lantern for projecting
the animated photographs. Another account states that it was acety¬
lene that was used, and that this exploded, whilst a third account
states that it was due to the carelessness of the operator in allow¬
ing a lot of the celluloid film to lie about, and that this caught fire.
Yet another story which has arisen on this side of the channel, is to
the effect that the celluloid itself caught fire owing to the concentra¬
tion of the heat of the lantern on the celluloid. Whatever was
the cause, the fire has caused a tremendous drop in the market, and
cinematographs and cinematographic shows are just now at a big
discount, and the makers of such apparatus are bewailing their
ill-luck.
Formalin. — rConsiderable attention is being paid at the present
time to the various photographic applications of formalin or
formic aldehyde, the use of which in photography has been pro¬
tected by patent. Its most valuable property is that of hardening
gelatin ; a film of gelatin soaked in the solution for about ten minutes
and then washed and dried can be treated with boiling water for
some length of time without being at all softened. As it seems
to have no ill-effects upon the progress of development nor upon
toning, except that of somewhat prolonging those operations, it
will be found to be a valuable substitute for the more troublesome
and less efficient alum.
The Latest in Colour Photography. — The most extraordinary
process in the reproduction of colour by photography is that of
Villedieu-Chassagne, which was shown first by Sir Henry Trueman
Wood at the Society of Arts. The process is, in brief, as follows : —
An ordinary print or positive is obtained and coated or painted
first with a blue solution, then with a green solution, and finally
with a red solution, and the silver image is in some way endowed
with the extraordinary power of so picking out the colours that the
final result is like nature. The patent specification describes the
preparation of those solutions, and after carefully examining it
there is no wonder that M. Dansac, one of the original inventors,
died in a lunatic asylum. The blue liquid is composed of about
sixteen of the metallic chlorides, even including the insoluble silver
chloride, dissolved (sic) in aqueous solution of albumin. Picric,
chromic, and oxalic acids and other reducing agents are freely
mixed with the chlorides, and so complicated is the whole thing
that it would be a good test question for the Major examination as
to what does happen ; and yet, in the face of all this, a company
called the “ Radiotint” Company, with a capital of £100,000, has
been formed to work the process, and the American rights have
been sold, it is said, for another £5000.
The Photographic Convention. — The annual photographic
convention is to be held this year at Great Yarmouth from J uly 12
to 17, under the presidency of Mr. F. P. Cembrano, jun. This annual
gathering is somewhat on a par with the British Pharmaceutical
Conference, with the’ difference, however, that there is, as a rule,
less work done at the photographic convention. The papers are
few and the excursions many, and even if there are a host of
cameras taken out on every excursion and hundreds of plates ex¬
posed each day, there is really very little solid work done. At the
same time it is a most enjoyable holiday, and one well worth
attending. The annual subscription is only 5s. , which admits to
full membership. Mr. R. P. Drage, of 95, Blenheim Crescent,
Notting Hill, W., is the Hon. Sec.
474
PHARMACEUTICAL JOURNAL.
[May 29, 1897
THE STUDENTS’ PAGE.
NOTES ON THE PHARMACOPCEIA.
Extra cta.— The extracts constitute a very important group of
galenical preparations. The main idea in preparing an extract of
any given drug is to obtain a concentrated preparation containing
the full activity of the drug free from the inert cellulose and woody
tissue which constitute the framework of vegetable structures. In
the case of succulent leaves or herbs, which can be obtained in the
fresh condition, evaporation of the expressed juioe, conducted with
suitable precautions, yields in many cases an extract having the
desired properties. In the case of drugs which are not available
in the fresh condition, or which yield little or no juice by
expression, such as most roots, stems, and barks, the general
process adopted is to exhaust the drug by treatment with a
suitable menstruum, and the residue obtained by the evaporation
of the fluid so obtained constitutes the extract. Before a rational
formula for the preparation of an extract of any given drug
can be constructed we must possess a knowledge of the substances
upon which the activity of the drug in question depends, so
as to select a menstruum which shall be capable of dissolving the
active principle or principles. The menstrua usually employed
are water, alcohol of various strengths, ether, and dilute acids.
Water is obviously the most economical menstruum to employ in
cases where its solvent action is satisfactory (extractum gentianse) ;
its use has, however, some drawbacks. Owing to the com¬
paratively high latent heat of steam, the evaporation of an
aqueous fluid requires the application of so much heat that
the extract is liable to suffer if the active principle is easily decom¬
posed, as in the case of many alkaloids. An aqueous extract also is
usually bulky, owing to the solubility in water of inert matters — -
chiefly gum and albumen (proteid)— which occur in more or less
abundance in all vegetable tissues. In both these respects alcohol
is superior to water as a menstruum, less heat being required for its
evaporation, and less inert material being dissolved by it than water.
Owing to the cost of alcohol the bulk of it is recovered by distilla¬
tion (ext. cannab. ind.); the portion retained by the marc being
recovered as much as possible by expression (ext. calumbse), or by
displacing it with water (ext. cascarse sagradse). The drug should
be exhausted with the smallest possible quantity of fluid in order
to minimise the duration of subsequent evaporation and consequent
risk of damaging the product. Evaporation is generally conducted
at the temperature of the water bath, never higher, and in certain
cases where that temperature is prejudicial, lower, e.g., 180° F.
vext. cinch, liq. ), 160° F. (ext. colchici), or 140° F. (“green”
extracts). Evaporation in vacuo, although not mentioned in any of the
official processes, is usually employed when working on a large scale,
particularly if a low temperature is necessary, since the time occu¬
pied by evaporation is very much diminished thereby. By reference
to the Pharmacopoeia the student will observe that the official pro¬
cesses for exhaustion are of a very heterogeneous nature. This is
partly due to the fact that each drug requires more or less special
treatment according to its physical properties and the nature of its
constituents ; and although there is little doubt that much greater
uniformity in the preparation of extracts is possible, the compilers
of the Pharmacopoeia would not be justified in altering, merely for
the sake of uniformity, the formula for an extract which has a time-
honoured reputation unless experimental work were available
showing that the medicinal activity of the product would not be
diminished thereby. Since the publication of the present edition
of the Pharmacopoeia in 1885 a good deal of experimental work has
been published in this direction. The student will best obtain a
knowledge of the official extracts by tabulating them for himself,
classifying them on the one hand according to the menstruum, and
on the other by the process employed in their manufacture. Do
not attempt to commit any process to memory, but endeavour
rather to obtain an intelligent grasp of the main principles
involved. In the case of solid extracts the Pharmacopoeia directs
the evaporation to be continued until the, product “is of a
suitable consistence for forming pills ” (extractum belladonna), or
“to the consistence of a soft extract” (extractum cannabis
indicae), or to a “ suitable consistence.” These directions are
rather vague, and admit of considerable variation in their interpre¬
tation ; the strength of solid extracts is consequently liable to
vary somewhat. Evaporation to dryness, as is directed for the
extracts of aloes, pareira, and logwood, would secure more
uniformity in this respect. Many extracts, however, will not
readily yield a dry extract, and the application of a prolonged heat
is to be avoided ; moreover, the dried product is not usually readily
s oluble again. Standardisation can only be applied to a few extracts,
since such a procedure requires a more intimate knowledge of the
active principles of many drugs than we possess. Again, any pro¬
cess of standardisation to be practicable must be simple and
capable of rapid completion. Liquid extracts are usually prepared
so that one fluid ounce contains the soluble constituents of one
ounce by weight of the drug. Such extracts, when prepared with
water, require the addition of alcohol to preserve them from de¬
composition.
Extractum Cinchona Liquidum. — Cinchona is a difficult drug
to exhaust without using a considerable quantity of menstruum.
The hydrochloric acid is employed with the intention of converting
the alkaloids into soluble hydrochlorates, and the cessation of pre¬
cipitation is intended to show that the percolate contains no more
alkaloid. In the process of standardisation solution of soda is
used to precipitate the alkaloids which are dissolved out by
agitation with benzolated amylic alcohol. Excess of soda is used
so as to retain as much as possible of the colouring matter in the
aqueous layer, which falls to the bottom of the separator. Note
the exact form in which the strength of the finished extract is
stated: “Five grains of the alkaloids of the bark in 100 fluid
rains.” This is neither 5 per cent, nor 5 grains per 100 minims,
ut 5 parts by weight in 100 parts by measure.
Extractum Nucis Vomicl®. — The alcoholic menstruum dis¬
solves out some of the oil from the seeds. The first step in the
process of standardisation provides for the removal of this by
chloroform, the alkaloids remaining in the diluted sulphuric acid.
After rejecting the chloroformic solution of fat, the acid solution is
made alkaline with ammonia : the alkaloids are precipitated, and
removed by agitation with more chloroform. Two ounces of
finished extract contain 131| grains of alkaloids, equal to
15 per cent. : —
100 : 15 : : 875 : 131£.
Note that the standardisation is applied to total alkaloid, i.e., to
brucine and strychnine, although the medicinal activity of nux
vomica depends almost entirely, if not quite, on strychnine alone.
The excuse for this is that the relative proportions in which the two
alkaloids occur in nux vomica is nearly constant ; for if in one extract
the total alkaloid consisted chiefly of stychnine,and in another chiefly
of brucine, the potency of the former would greatly exceed that
of the latter, although the percentage of total alkaloid might be
the same in both cases. Moreover, there is no simple process
known for determining the two alkaloids separately, chiefly owing
to the similarity in the solubility of their salts. In the B. P. test,
the fat is removed by saponifying it with sodium carbonate,
which also precipitates the alkaloids, the latter being removed
by means of chloroform, in which the saponified oil is in¬
soluble. To effect a further purification the latter is shaken
with diluted sulphuric acid, the alkaloids being converted into
sulphates, and consequently pass from the chloroform to the
aqueous fluid. On rendering the latter alkaline the liberated
alkaloids pass again to the fresh chloroform (see the notes on
immiscible solvents under “Cinchonse Rubrse Cortex” in the
Students’ Page).
Extractum Opii and Extractum Opii Liquidum. — These will
be fully dealt with under Opium. The assay process of opium
forms the basis of the standardisation of both these extracts.
Ferri Arsenias. — Note that sodium arseniate, Na2HAs04, is an
acid salt, i.e., one in which the hydrogen of the arsenic acid,
HsAs04, is only partially replaced by the metal, whereas ferrous
arseniate, Fe32As04, is a normal salt. Hence double decomposi¬
tion between Na2HAs04 and FeS04 results in the liberation of
sulphuric acid as well as the formation of ferrous arseniate —
2Na2HAs04 + 3FeS04 = Fe32As04 + H2S04 + 2Nai.S04.
Since arseniate of iron is soluble in dilute acids, the sodium bicar¬
bonate is added to neutralise this sulphuric acid and secure the
complete precipitation of the iron arseniate. The ferrous arseniate
becomes to a large extent oxidised during the process of washing
and drying, hence the hydrochloric acid solution gives a precipi¬
tate with both ferro- and ferri-cyanide of potassium. When boiled
with caustic soda, sodium arseniate is formed, and a mixture of
ferrous and ferric hydrates precipitated. The filtrate containing
the sodium arseniate requires exactly neutralising with nitric acid,
since the excess of caustic soda used in boiling would precipitate
oxide of silver on the addition of silver nitrate, and so obscure the
characteristic brick-red colour of the silver arseniate. Excess of
nitric acid, on the other hand, prevents the appearance of the
brick red precipitate, silver arseniate being soluble in nitric acid.
May 29, 1897J
PHARMACEUTICAL JOURNAL.
475
Pharmaceutical Journal.
A Weekly Record of Pharmacy and Allied Sciences-
ESTABLISHED 1841.
Circulating in the United Kingdom, France, Germany,
Austria, Italy, Russia, Switzerland, Canada, the
United States, South America, India,
Australasia, South Africa, etc.
Editorial Office : 17, BLOOMSBURY SQUARE, W.G.
Publishing at)d Advertising Office : 5, SERLE STREET, W.G.
LONDON: SATURDAY, MAY 29, 1897.
THE RECENT COUNCIL ELECTION.
The result of the Council election is the subject of a letter
by Mr. Leo Atkinson in this week’s J ournal (see page 483),
and there is good reason to believe that the opinions he
-expresses are shared by many other supporters of the
Pharmaceutical Society. Whether the charge of fickleness
and ingratitude on the part of the electorate is well-founded
need not enter into consideration here, for after all the
Society is essentially a democratic body, and no one expects
■democracies to he pervaded with sentiment. It may he
pointed out, however, that in practice change of policy is often
found to he desirable in democracies, and the electors, who
alone possess the power of insisting upon such a change,
are not of necessity fickle in enforcing it. Then, again,
gratitude to individuals who have done good service in the
past should hardly he allowed to serve as a sufficient reason
for unthinkingly following their lead on all occasions in the
future. But, leaving these matters for the individual con¬
sideration of members of the Society, we may proceed to
Mr. Atkinson’s next point, which is of great interest as
hearing on a problem that has been much debated of late.
The development of the anti cutting movement has led to
what our correspondent and many others regard as an “ unholy
alliance ” between registered chemists and other tradesmen, to
■maintain the prices at which a certain class of medicinal pre¬
parations, amongst others, shall be retailed to the public. The
question whether chemists and druggists ought to recognise
•any right on the part of other tradesmen to deal in such
articles has been waived, and those who have agreed that it
should be left out of sight for the time being have thus
relinquished a position which they will find it difficult, if
not impossible, to re-occupy.
As Mr. Atkinson suggests, it is quite possible that many,
if not the majority, of those chemists and druggists who
bave associated themselves with the promoters of this
scheme for the better regulation of prices, may have been
guided by sympathy for their less prosperous fellows rather
than influenced by any hope of ultimate benefit to the craft
resulting from such a combination. If that be so, now that they
have realised the strength from a political aspect of the
weapon they have helped to bring into use for a totally
different purpose, they will doubtless be inclined to take time
for reflection. It may be an extreme view of the case to see
in any considerable expansion of this “ unholy alliance ” the
possibility of the future Council of the Pharmaceutical
Society being “ elected, dominated, and its policy determined
at the sweet will of the Grocers’ Federation.” Nevertheless,
members of the Society have undoubted reason for alarm
when a body whose executive includes several individuals
whose only connection with pharmacy is a commercial one,
seeks to influence the election of those responsible for the
protection of the professional interests of pharmacy. Mr.
IIyslop, who — though unsuccessful on this occasion — did re¬
markably well for a first candidature, strikes a kindred note
of warning in his letter, and it may be left to the good sense
of the electors to ensure the non-fulfilment of the prophecy
of evil foreseen on various hands. It is very necessary, however,
that electors should realise the fact that the voting power they
possess is not merely a privilege, but a duty they owe to those
who are willing to undertake theexecutive work. Everyone
who possesses voting power should exercise it, and as the
method of voting is simplicity itself, it is hard to conceive of
any intelligible reason for not doing so in the vast majority of
instmees.
It is interesting to note that even the Grocers’ Federation
is not entirely at one with the Proprietary Articles Trade
Association. At a recent meeting of the former body,
one speaker put it that “Mr. Glyn-Jo\es requests the
power of this association to run his show,” though it must
be added that another speaker immediately remarked that
“supposing in running his show he was going to put
hundreds and thousands of pounds into the pockets of the
grocers, and did no harm, why should they not help him
to run his show 1 ” But what might do no harm from the
grocers’ point of view, which is probably to secure the
maximum of profit with a minimum of trouble, may result
in utter disaster to the best pharmaceutical interests. As
a professional body, the Pharmaceutical Society cannot stoop
to the methods of a trade union, and it is difficult to see,
therefore, what benefit can accrue to any one from candi¬
dates for seats on the Council of the Society expressing
sympathy with trade union methods. Such sympathy, it
is claimed, was expressed by a large majority of the candidates
at the recent election, but we understand that a perusal of
the letters upon which that claim was based hardly
justifies such a separation into sheep and goats as was
attempted. At any rate the agitation set on foot was quite
beside the matter, and fortunately the result was not
materially influenced. Apparently, it may still be assumed
as axiomatic that whilst members of the Society have no
objection to any elector voting as he thinks proper, and even
attempting to influence the votes of others, they maintain
a fixed objection to being dictated to on such matters by an
outside body whose machinery is set in motion to act in a
direction that was not anticipated when their support to that
body was solicited. But they ought to take warning from
what took place, lest worse happen in the future. Last
week the fact was recorded with much regret that more
than seventeen hundred voting papers had not been returned,
whilst nearly a hundred were rejected because they were
informal or received by post too late. With regard to informal
and late votes, one can only wonder at the apparent lack
of intelligence displayed in the face of such explicit in¬
structions as each voter receives. As to those who did not
vote, we can only reiterate that they were guilty of a grave
error of judgment in neglecting their most important duty
as members of the Society.
476
PHARMACEUTICAL JOURNAL.
[May 29, 1897 '
ANNOTATIONS,
The Benevolent Fund List of donations and new or increased
annual subscriptions, paid or promised in response to the special
decennial appeal, still remains open, and a list of any further con¬
tributions received or promised on or before Monday next, May 31,
will be published in the Journal next week. It has been hoped
that it might be possible to announce at least another five hundred
pounds by that time, and though present prospects do not lend
much support to that idea, a timely reminder may go far towards
aiding its realisation. As already pointed out, thisis the only special
insurance fund British pharmacy possesses, find by establishing a
great record this year, it may be possible to secure the Fund upon a
much more satisfactory financial basis than has ever yet been possible.
Three Pharmaceutical Scholarships will be offered for com¬
petition on Tuesday, July 13 — two Jacob Bell Memorial Scholar¬
ships and the Manchester Pharmaceutical Association Scholarship
_ and it is important that intending competitors should not over-
ook the fact that all entries must be in the hands of the Registrar,
17, Bloomsbury Square, W.C., on or before Tuesday next, June 1.
The Bell Scholars will receive thirty pounds each, in addition to
free laboratory instruction and admission to the lectures at the
School of Pharmacy for the Session 1897-98, and books of the value
of fifty shillings, given under a bequest of the late Thomas Hyde
Hills. The Manchester Pharmaceutical Association Scholarship is
worth about twenty-six pounds.
The School op Pharmacy Students’ Association will hold a
meeting on Friday next, at 8 p.m., June 4, when Mr. E. J. Wall,
F.R.P.S., Editor of the Photographic Neivs, will deliver a lecture
on “Some Applications of Photography.” In this he will deal
with the application of photography to astronomical research,
agriculture, meteorology, geology, botany, entomology, criminal
jurisprudence, the study of animal locomotion, and as a means for
the expression of pictorial effects. The lecture will be illustrated
by about a hundred lantern slides, and should attract a large
audience. The chair will be taken by the l)ean of the School, Pro¬
fessor Greenish, and we are desired to announce that any former
students or friends of the School will be welcome on this occasion.
Mr. Taplin’s Letter, which was received just as we were going
to press last week (see page 464d), raises a question' with regard to
notices of motion that merits a little attention, inasmuch as others
may hold similar views with regard to the alleged unfairness of
the Chairman in not allowing the motions to be put at the general
meeting. The explanation of the matter appears to be that the
President had no authority to deal in any way with the
notices of motion until the meeting had been opened.
We take it that any notice of motion sent to the
Secretary by a member of a Society must be accepted by him
without demur, and no one is entitled to say officially whether or
not it is in order except the Chairman of the meeting at which it
is proposed to put the motion. The President is not Chairman
until he has actually taken the chair at the meeting, and then
only does he become endowed with authority to allow motions to
be put, or the reverse. Whilst, therefore, an apparent hardship
may be inflicted at times, there is no ground whatever for
suggesting that either the Secretary or the President did any¬
thing in the matter that was not strictly in order.
The Storage of Drugs and Arrangement of the Pharmacy
are matters that deserve greater attention than they receive
usually, and Mr. Hyslop’s paper, read on Wednesday last, is there¬
fore one to be welcomed. He shows that the climatic conditions
of the pharmacy form an interesting study that may be pursued
alike with pleasure and profit in the intervals during the day’s1,
work, that pharmacists know only too well. It is matter of com¬
mon remark that all the work spread over a long day in the phar¬
macy might often be condensed into a few hours if clients would
but arrange accordingly. Failing that happy state of affairs,,
however, Mr. Hyslop presents a useful alternative in the study of
the thermal, hygroscopic, and barometric conditions of the pre¬
mises, and the proper adaptation of the latter to all their varying-
needs. Apprentices, assistants, and master pharmacists may
equally profit by a perusal of this practical paper, and it is quite cer¬
tain that readers will be glad to welcome many others of similar type.
William Allen, the first president of the Pharmaceutical
Society, is referred to in an interesting letter that appears in
the Christian World. Speaking of the late Duke of Kent, the
father of our present Queen, the writer of the letter — Mr. Roberta
Barling, of Staplehurst — says : “ One of the most intimate of the*
Duke’s friends was William Allen, of Plough Court, one of London’s
merchant princes, at whose house such celebrities as Wilberforce,
Brougham, and others often met for philanthropic purposes. Ilis
great wealth was often at the Duke’s disposal, and the Quaker of
Plough Court, by his forethought and liberality, supplied the
means by which the Queen of these realms was born in England.”
The General Medical Council met for its sixty-second session
on Tuesday, when the chair was taken by the President, Sir
Richard Quain. In the course of his address he stated that the
material for the new British Pharmacopoeia had been completed*
and would be placed before the Council during the present session.
It may be anticipated, therefore, that the approximate date of
publication of the work may shortly be announced. There was-
nothing else of special interest to our readers in the address, buf
we regret to note that the health of the Registrar, Mr. Miller, has
so far failed that he has felt it his duty to send in his resignation.
The Use of Diphtheria Antitoxin during the past year has
just been reported on by the medical superintendents of the
Metropolitan Asylums Board, and the figures presented confirm
and extend the favourable conclusions reached in the previous
year, the first during which antitoxin was used by the Board.
Comparison is made with 1894, the year in which the lowest
mortality was recorded prior to the introduction of antitoxin, and
a marked improvement is manifested in all classes of cases,
especially in the severer ones, as will be seen from the following
tabular statement, showing the percentage of mortality to cases : —
Year.
All cases.
Under 5 years.
Laryngeal.
Tracheotomy.
1894 .
29-6
47‘4
62-0
70-4
1896 .
20‘S
30-2
29-6
41-0
The percentage of laryngeal cases requiring tracheotomy was
reduced from 56 '0 to 41 ‘0, and in post-scarlatinal diphtheria the
mortality was reduced to 5 per cent. , the average for five years
before 1894 having been 50 per cent. The clinical effects of the
treatment observed are a diminution of the faucial swelling and
consequent distress ; a lessening, if not entire cessation, of the
irritating and offensive discharge from the nose ; a limitation of
the extension of membrane ; and an earlier separation of the
exudation. It is worthy of note that in one hospital under the
Board antitoxin was used to a much less extent than in the rest*
and that is the only hospital which shows no improvement in
results over 1894.
May 29, 1897]
PHARMACEUTICAL JOURNAL.
477
The Serum Used was supplied by'Dr. Sims Woodhead'from the
1 aboratories of the Royal Colleges of Physicians and Surgeons. It
i s described as being of greater strength and more uniform than
that previously obtained, and the dosage could be more accurately
regulated. The importance of early treatment is shown by the
fact that a dose of 2000 units will usually secure a result on the
first day which 50,000 will not effect on the fourth. Though a
considerable increase of complications was noticed, especially of
albuminuria and paralysis, the medical superintendents attach
but little importance to that. Some of the increase is no doubt
accounted for by the fact that many severe cases recover which
would otherwise have ended fatally. The general conclusions
reached are that antitoxin causes a great reduction in the
mortality of cases brought under treatment on the first three days
of illness, whilst there is a lowering of the combined general
mortality to a point below that of any former year, and a
still more remarkable reduction in the mortality of the laryngeal
cases. A uniform improvement was also observed in the results
of tracheotomy at each separate hospital, as well as a bene¬
ficial effect in the clinical course of the disease. The results
recorded for 1896 are somewhat better than those for 1895, and it
is added that the superintendents still hold to the opinion that in
the antitoxic serum a remedy is possessed of distinctly greater
value in the treatment of diphtheria than any other with which
they are acquainted.
The Treatment of Wounds by Oxygen Gas is now in active
operation at the Oxygen Home, Fitzroy Square, which was form¬
ally opened by the Princess Louise last week. The new system of
oxygen treatment was discovered by Dr. George Stoker, brother
of Mr. Bram Stoker, of the Lyceum Theatre. It depends on
exposure of the affected parts — wounds, ulcers, etc. — to the action
of oxygen gas, and the ailments are said to disappear as if by
magic. It is stated that the new method of treatment was sug¬
gested to Dr. Stoker by the Zulus, who, when they are wounded,
climb an eminence and expose their wounds to the pure air of the
mountain tops. After the Russo-Turkish War he also noticed that
the invalids sat with their wounded limbs bare on the deck and
profioed thereby. The idea thus suggested has been scientifically
developed, and during the past nine months exceeding favourable
results have been obtained. At the Oxygen Home a gasometer is
kept filled with a mixture of equal parts of oxygen and purified
air, and vessels filled with the mixture from the gasometer are
attached to special chambers which enclose the wounds.
Deaths caused by Poisons and Poisonous Vapours numbered
598 in 1895, including 389 males and 209 females. Of the former
116 succumbed to the effects of lead poisoning ; opium, laudanum,
and morphine accounted for 63 ; chloroform 43 ; carbolic acid 11 ;
chlorodyne 9 ; chloral 8 ; and belladonna 7 ; no other poison being
responsible for more than five deaths. Amongst women, opium,
laudanum, and morphine are credited with 40 deaths ; lead 27 ;
chloroform 25 ; carbolic acid 23 ; ammonia 6 ; and others for
smaller numbers.
The Proposed Psychological Laboratory at University
College, London, will be carried on in conjunction with the
work of the Physiological and Psychological Departments, and
under the guidance of Professors Schafer and Sully, the latter of
whom is acting as honorary secretary of the Committee. To start
the laboratory about £200 per annum is required. Professor Sully
has received £70 towards the cost of instruments from a lady
formerly a student at University College, and he now appeals
for further help.
LITERARY NOTES.
‘On the Therapeutic Value of the Hydrocarbons,’ is a
pamphlet by Professor Bayer, of Brussels, who makes special
reference to the use of the compounds dealt with, in the treatment
of diseases of the respiratory organs and particularly of
tuberculosis. The hydrocarbon more particularly referred to is
the so-called oxygenated petroleum (vaselina oxygenata), or Valsol-
Klever. Copies of the pamphlet may be obtained from Mr. William
Poppelreuter, 54, Portland Street, Manchester.
The ‘ Manuale der neuen Arzneimittel,’ by J. Mindes, is a
useful compilation in which the more essential particulars are
given concerning more than two thousand new remedies, a large
proportion of which have probably never been heard of by British
pharmacists. The book is arranged in dictionary form and a capital
index is included within its three hundred and thirty-five pages.
Medical men and pharmacists who can read German will find the
compilation an indispensable work of reference. It is published
at the Art. Institut Orell Ftissli, Zurich, at five shillings.
‘Quarantine in England’ was the subject of the Milroy
lectures, delivered at the Royal College of Physicians by Dr.
William Collingridge, and they have now been re-published from
the Lancet in pamphlet form. It is interesting to note that Dr.
Collingridge is of opinion that the theory on which the system of
modern quarantine is based is untenable, and that in practice it
has failed to confer any real protection on those countries which
practise it. An effective quarantine is shown to be practically
impossible in a commercial country, whilst sanitation and a rational
system of medical inspection have proved more efficacious and less
burdensome.
‘ The Imperial Text-Book, of Photography,’ by E. J. Wall,
F.R.P.S., is a compact work of one hundred and twenty pages,
the special claim' of which to attention is the fact that every
process recommended has been personally tested and proved. This
is so much more than can usually be said of any book that it
ought to direct the attention of amateurs to the ‘ Imperial Text-
Book.’ Cameras, lenses, plates, dark rooms, and all the hundred
and one points in photography that require attention are carefully
dealt with, and there is little doubt that the publisher’s estimate
of the book as “a satisfactory guide to the practice of photography”
will be confirmed by many. It is published in a neat cloth cover
at one shilling, by the Imperial Dry Plate Co., Ltd., Crickle-
wood, N.W.
Technical Education, as encouraged by the City and Guilds of
London Institute, continues to thrive, and the latest Report to the
Governors, at the head of whom is the Prince of Wales as Presi¬
dent, is quite a bulky volume. The total number of students in
attendance at the Central Technical College during 1895-6 was 214,
rather more than the previous year, and at the close of the Session
the diploma of Associate of the City Guilds Institute was awarded
to 46 matriculated third-year students. A considerable amount of
research work has been done in the laboratories of the College by
the more advanced students, in conjunction with the Professors,
and the results in many cases have been communicated to the
Royal Society and other bodies. The amount received in students’
fees during the year was £4876 11s. 8d. The Technical College,
Finsbury, has also continued to do good work, and altogether there
is continued evidence of the great value and importance of the
services rendered to technical education by the City and Guilds 'of
London Institute.
478
PHARMACEUTICAL JOURNAL.
[Mat 29, 1897
BRITISH ASSOCIATION FOR THE
ADVANCEMENT OF SCIENCE.
• - ♦ -
BOTANICAL SECTION.
OPENING ADDRESS BY
D. H. SCOTT, M.A., Ph.d , F.R.S.
"Honorary Keeper of the Jodrell Laboratory, Royal Gardens, Kew,
President of the Section.
THE PRESENT POSITION OF MORPHOLOGICAL BOTANY
( Concluded from page 861. )
Chalazogamy.
Among the most striking results of recent years bearing on the
morphology of the higher plants, Treub’s discovery of the struc¬
ture of the ovule and the mode of fertilisation in Casuarina must
undoubtedly be reckoned. The fact that the pollen-tube in this
genus does not enter the micropyle, but travels through the
tissues of the ovary to the chalaza, thus reaching the base of the
embryo-sac, was remarkable enough in itself, and when considered
in connection with the presence of a large sporogenous tissue pro¬
ducing numerous embryo-sacs, appeared to justify the separation
of this order from other angiosperms. Then came the work of
Miss Benson in England, and of Nawaschin in Russia, showing
that these remarkable peculiarities are by no means confined to
Casuarina, but extend also in various modifications to several
genera of the Cupuliferie and Ulmaceas. They are not, however,
constant throughout these families, so that we are no
longer able to attach to these characters the same fundamental
systematic importance which their first discoverer attri¬
buted to them. It is remarkable, however, that these de¬
partures from the ordinary course of angiospermous development
occur in families some of which have been believed on other
grounds to be among the most primitive Dicotyledons.
Evidence of Descent derived from Fossil Botany.
At the beginning of this address I spoke of the importance of
the comparatively direct evidence afforded by fossil remains as to
the past history of plants. It may be of interest if I endeavour to
indicate the directions in which such evidence seems at present to
point.
It was Brongniart who in 1828 first arrived at the great genera¬
lisation that “ nearly all of the plants living at the most ancient
geological epochs were Cryptogams,”* a discovery of unsurpassed
importance for the theory of evolution, though one which is now
so familiar that we almost take it for granted. Those palseozoic
plants which are not Cryptogams are Gymnosperms, for the angio¬
spermous flowering plants only make their appearance high up in
the secondary rocks. Even the Wealden flora, recently so care¬
fully described by Mr. Seward, one of the secretaries to this
section, has as yet yielded no remains referable to Angiosperms,
though this is about the horizon at which we may expect their
earliest trace to be found.
Attention has already been called to the enormous antiquity of
the higher Cryptogams— the Pteridophyta— and to the striking fact
that they are accompanied, in the earliest strata in which they have
been demonstrated with certainty, by well-characterised Gymno¬
sperms. The Devonian flora, so far as we know it, though an early,
was by no means a primitive one, and the same statement applies
still more strongly to the plants of the succeeding Carboniferous
epoch. The palaeozoic Cryptogams, as is now well known, being
the dominant plants of their time, were in many ways far more
highly developed than those of our own age ; and this is true of all
the three existing stocks of Pteridophyta, ferns, lycopods, and
Equisetineae.
We cannot therefore expect any direct evidence as to the origin
of these groups from the palaeozoic remains at present known to
us, though it is, of course, quite possible that the plants in question
have sometimes retained certain primitive characters, while
reaching in other respects a high development. For example, the
general type of anatomical structure in the young stems of the
Lepidodendreae was simpler than that of most Lycopods at the
present day, though in the older trunks the secondary growth,
correlated with arborescent habit, produced a high degree of com-
* Williamson, ‘ Reminiscences of a Yorkshire Naturafist,’ 1896, p. 198.
plexity. On the whole, however, the interest of the palseozoic
Cryptogams does not consist in the revelation of their primitive
ancestral forms, but rather in their enabling us to trace certain
lines of evolution further upward than in recent plants. From the
Carboniferous rocks we first learn what Cryptogams are capable of.
In descending to the early strata we do not necessarily trace the
trunk of the genealogical tree to its base ; on the contrary, we
often light on the ultimate twigs of extensive branches which died'
out long before our own period.
In a lecture which I had the honour of giving last May before
the Liverpool Biological Society, I pointed out how futile the
search for ‘ ‘ missing links ” among fossil plants is likely to be.
The lines of descent must have been so infinitely complex in their-
ramification that the chances are almost hopelessly great against,
our happening upon the direct ancestors of living forms. Among
the collateral lines, however, we may find invaluable indications,
of the course of descent.
Fossil botany has revealed to us the existence in the Carbon¬
iferous epoch of a fourth phylum of vascular Cryptogams quite
distinct from the three which have come down — more or less re¬
duced — to pur own day. This is the group of Sphenophyllese,
plants with slender ribbed stems, superposed whorls of more or-
less wedge-shaped leaves, and very complex strobili with stalked
sporangia. The group to a certain extent combines the characters,
of Lycopods and Horsetails, resembling the former in the
primary anatomy, and the latter, though remotely, in external
habit and fructification. Like so many of the early Cryptogams,.
Sphenophyllum possessed well-marked cambial growth. One may-
hazard the guess that this interesting group may have been derived,
from some unknown form lying at the root of both Calamites and
Lycopods. The existence of the Sphenophyllese certainly suggests,
the probability of a common origin for these two series.
In few respects is the progress made recently in fossil botany-
more marked than in our knowledge of the affinities of the
Calamariese. Even so recently as the publication of Count Solms-
Laubach’s unrivalled introduction to ‘ Fossil Botany,’ the relation
of this family to the Horsetails was still so doubtful that the author
dealt with the two groups in quite different parts of his book.
This is never likely to happen again. The study of vegetative-
anatomy and morphology on the one hand, and of the perfectly-
preserved fructifications on the other, can leave no doubt that the-
fossil Calamariese and the recent Equiseta belong to one and the
same great family, of which the palseozoic representatives are,
generally speaking, by far the more highly organised. This is not.
only true of their anatomy, which is characterised by secondary
growth in thickness just like that of a Gymnosperm, but also
applies to the reproductive organs, some of which are distinctly
heterosporous. In the genus Calamostachys we are, I think, able-
to trace the first rise of this phenomenon.
The external morphology of the cones is also more varied and
usually more complex than that of recent Equiseta, though in
some Carboniferous forms, as in the so-called Calamostachys
tenuissima of Grand’ Eury, we find an exactly Equisetum-like-
arrangement.
The position of the Sigillarise as true members of the Lycopod
group is now well established. The work of Williamson proved
that there is no fundamental distinction between the vegetative
structure of Lepidodendron, which has always been recognised as
lycopodiaceous, and that of Sigillaria. Secondary growth in
thickness, the character which here, as in the case of the Calamo-
dendrese, misled Brongniart, is the common property of both
genera. Then came Zeiller’s discovery of the cones of Sigillaria ,
settling beyond a doubt that they are heterosporous Cryptogams.
A great deal still remains to be done, more especially as to the-
relation of Stigmaria to the various types of lycopodiaceous stem.
At present we are perhaps too facile in accepting Stigmaria
ficoides as representing the underground organs of almost any
carboniferous Lycopod.
We are now in possession of a magnificent mass of data for the
morphology of the palseozoic lycopods, and have perhaps hardly
yet realised the richness of our material. I refer more especially
to specimens with structure, on which, here as elsewhere, the
scientific knowledge of fossil plants primarily depends.
It is scarcely necessary to repeat what has been said so often,
elsewhere, that the now almost universal recognition of the-
cryptogamic nature of Calamodendrese and Sigillarise is a splendid?
triumph for the opinions of the late Professor Williamson, which
he gallantly maintained through a quarter of a century of:
controversy.
May 29, 1897]
PHARMACEUTICAL JOURNAL.
479
Perhaps, however, the keenest interest now centres in the Ferns
and fern-like plants of the carboniferous epoch. No fossil remains
•of plants are more abundant, or more familiar to collectors, than
the beautiful and varied fern-fronds from the older strata. The
mere form, and even the venation of these fronds, however, really
tell us little, for we know how deceptive such characters may be
among recent plants. In a certain number of cases, discovery of
the fructification has come to our aid, and where sori are found we
-can have no more doubt as to the specimens belonging to true Ferns.
The work of Stur and Zeiller has been especially valuable in this
•direction, and has revealed the interesting fact that a great many
•of these early Ferns showed forms of fructification now limited to
the small order Marattiaceae. I think perhaps the predominance
of this group has been somewhat exaggerated, but at least there is
no doubt that the marattiaceous type was much more important
then than now, though it by no means stood alone. In certain
•cases the whole fern-plant can be built up. Thus Zeiller and
Renault have shown that the great stems known as Psaronius, the
structure of which is perfectly preserved, bore fronds of the
Pecopteris form, and that similar Pecopteris fronds produced the
fructification of Aster otheca, which is of a marattiaceous
•character. Hence, for a good many Carboniferous and
Permian forms there is not the slightest doubt as to their fern-
nature, and we can even form an idea of the particular group of
Ferns to which the affinity is closest.
I will say nothing more as to the true Ferns, though they present
innumerable points4 of interest, but will pass on at once to certain
forms of even greater importance to the comparative morphologist.
A considerable number of palceozoic plants are now known which
present characters intermediate between those of Ferns and
Cycadese. I say present intermediate characters, because that is
a safe statement ; we cannot go further than this at present, for
we do not yet know the reproductive organs of the forms in
•question.
In Lyginodendron, the vegetative organs of which are now
completely known, the stem has on the whole a cycadean structure ;
the anatomy, which is preserved with astonishing perfection,
presents some remarkable peculiarities, the most striking being
that the vascular bundles of the stem have precisely the same
arrangement of their elements as is found in the leaves
of existing Cycads, but nowhere else among living plants.
The roots also, though not unlike those of certain
ferns in their primary organisation, grew in thickness by means of
•cambium, like those of a Gymnosperm. On the other hand, the
leaves of Lyginodendron are typical fern-fronds, having the form
■characteristic of the genus Sphenopteris, and being probably
identical with the species S. hceninghausi, Their minute struc¬
ture is also exactly that of a fern-frond, so that no botanist would
■doubt that he had to do with a Fern if the leaves alone were
before him.
This plant thus presents an unmistakable combination of cyca¬
dean and fern -like characters. Another and more ancient genus,
Heterangium, agrees in many details with Lyginodendron, but
•stands nearer the ferns, the stem in its primary structure resem¬
bling that of a Gleichenia, though it grows in thickness like a
cycad. These intermediate characters led Professsor Williamson
and myself to the conclusion that these two genera were derived
from an ancient stock of Ferns, combining the characters of
•several of the existing families, and that they had already con¬
siderably diverged from this stock in a cycadean direction. I
believe that recent investigations, of which I hope we shall hear
more from Mr. Seward, tend to supply a link between Lyginoden¬
dron and the more distinctly cycadean stem known as Cycadoxylon.
Heterangium first appears in the Burntisland beds, at the base
•of the carboniferous system ; from a Similar horizon in Silesia, Count
Solms-Laubach has described another fossil, Protopitys bucheana,
the vegetative structure of which also shows, though in a different
form, a striking union of the characters of Ferns and Gymno¬
sperms. Count Solms shows that this genus cannot well be
included among the Lyginodendrese, but must be placed in a
family of its own, which, to use his own words, “increases the
number of extinct types which show a transition between the
■characters of Filicinese and of Gymnosperms, and which thus
might represent the descendants in different directions of a primi¬
tive group common to both.”*
Another intermediate group, quite different from either of the
foregoing, is that of the Medullosete, fossils most frequent in the
Upper Carboniferous and Permian strata. The stems have a
remarkably complicated structure, built up of a number of
distinct rings of wood and bast, each growing by its own cambium.
Whether these rings represent so many separate primary cylinders,
like those of an ordinary polystelic fern, or are entirely the
product of anomalous secondary growth, is still an open question,
on which we may expect more light from the investigations of
Count Solms. In any case, these curious stems (which certainly
suggest in themselves some relation to Cycadese) are known to have
borne the petioles known as Myeloxylon, which have precisely the
structure of cycadean petioles. *
Renault has fui’ther brought forward convincing evidence
that these Myeloxylon petioles terminated in distinctly
fern-like foliage, referable to the form-genera Alethopteris
and Neuropteris. Hence it is evident that the fronds
of these types, like some specimens of Sphenopteris, cannot be
accepted as true Ferns, but may be strongly suspected of belong¬
ing to intermediate groups between Ferns and Cycads.
It is not likely (as has been repeatedly pointed out elsewhere)
that any of these intermediate forms are really direct ancestors of
our existing Cycads, which certainly constitute only a small and
insignificant remnant of what was once a great class, derived, as I
think the evidence shows, from fern-like ancestors, probably by
several lines of descent.
One of the greatest discoveries in fossil botany was undoubtedly
that of the Cordaitese — a fourth family of Gymnosperms, quite dis¬
tinct from the three now existing, though having certain points in
common with all of them. They are much the most ancient of the
four stocks, extending back far into the Devonian. Nearly all the
wood of Carboniferous age, formerly referred to Conifers; under
the name of Dadoxylon or Araucarioxylon, belonged to these
plants. Thanks chiefly to the brilliant researches of Renault
and Grand’ Eury, the structure of these fine trees is now known
with great completeness. The roots and stems have a coniferous
character, but the latter contain a large, chambered pith different
from anything in that order. The great simple lanceolate or
spatulate leaves, sometimes a yard long, were traversed by a number
of parallel vascular bundles, each of which has the exact structure
of a foliar bundle in existing Cycadeax This type of vascular
bundle is evidently one of the most ancient and persistent of
characters. Both the male and female flowers ( Cordaianthus ) are
well preserved in some cases. The morphology of the former has
not yet been cleared up, but the stamen, consisting of an upright
filament bearing 2-4 long pollen-sacs at the top, is quite unlike
anything in Cycadeae ; a comparison is possible either with Gingko
or with the Gnetaceae.
In the female flowers — small cones — the axillary ovules appear
to have two integuments, a character which resembles Gnetaceae
rather than any other Gymnosperms. Renault’s famous discovery
of the prothallus in the pollen-grains of Cordaites indicates the
persistence of a cr.yptogamic character ; but it cannot be said that
the group as a whole bears the impress of primitive simplicity,
though it certainly combines in a remarkable way the characters
of the three existing orders of the Gymnosperms.
There is one genus, Poroxylon, fully and admirably investigated
by Messrs. Bertrand and Renault, which from its perfectly pre¬
served vegetative structure (and at present nothing else is known)
appears to occupy an intermediate position before the Lygino¬
dendrese and the Cordaitese. The anatomy of the stem is almost
exactly that of Lyginodendron, the resemblance extending to the
minutest details, while the leaves seem to closely approach those
of Cordaites. Poroxylon is at present known only from the Upper
Carboniferous, so we cannot regard it as in any way representing
the ancestors of the far more ancient Cordaiteae. The genus
suggests, however, the possibility that the CordaiteaB and the
Cycadeae (taking the latter term in its wide sense) may have had a
common origin among forms belonging to the filicinean stock. It
is also possible that the CordaiteaB, or plants allied to them, may in
their turn have given rise to both Coniferae and Gnetaceae.
It is unfortunate that at present we do not know the fructifica¬
tion of any of the fossil plants which appear to be intermediate
between ferns and Gomnosperms. Sooner or later the discovery
will doubtless be made in some of these forms, and most interest¬
ing it will be. M. Renault’s Cycadospadix from Autun appears to
show that very cycad-like fructifications already existed in the
later Carboniferous period, and numerous isolated seeds point in
the same direction, but we do not know to what plants they
belonged.
* Bot. Zeitung, 1893, p. 207.
* Seward, ‘ Anna’s of Botany,’ vol. vii., p. 1.
480
PHARMACEUTICAL JOURNAL.
[May 29, 1897
I think we may say* that such definite evidence as we already
possess decidedly points in the direction of the origin of Gymno-
sperms generally from plants of the Fern series rather than from a
lycopodiaceous stock.
I must say a few words before concluding on the eycad-like
fossils which are so striking a feature of mesozoic rocks, although I
feel that this is a subject with which my friend Mr. Seward is far
more competent to deal. Both leaves and trunks of an unmis¬
takably cycadean character are exceedingly common in many
mesozoic strata, from the Lias up to the Lower Cretaceous. In
some cases the structure of the stem is preserved, and then it
appears that the anatomy as well as the external morphology is,
on the whole, cycadean, though simpler, as regards the course of
the vascular bundles, than that of recent representatives of the
group.
Strange to say, however, it is only in the rarest cases that fruc¬
tifications of a truly cycadean type have been found in association
with these leaves and stems. In most cases, when the fructifica¬
tion is accurately known, it has turned out to be of a type totally
different from that of the true Cycadeaa, and much more highly
organised. This is the form of fructification characteristic of
Bennettites, a most remarkable group, the organisation of which
was first revealed by the researches of Carruthers, afterwards ex¬
tended by those of Solms-Laubach and Lignier. The genus
evidently had a great geological range, extending from the Middle
Oolite (or perhaps even older strata) to the Lower Greensand.
Probably all botanists are agreed in attributing cycadean
affinities to the Bennettitess, and no doubt they are
justified in this. Yet the cycadean characters are entirely
vegetative and anatomical ; the fructification is as different as
possible from that of any existing cycad, or, for that matter, of
any existing Gymnosperm. At present, only the female flower is
accurately known, though Count Solms has found some indications
of anthers in certain Italian specimens. The fructification of the
typical species, B. gibsonianus, which is preserved in marvellous
perfection in the classical specimens from the Isle of Wight, ter¬
minates a short branch inserted between the leaf-bases, and consists
of a fleshy receptacle bearing a great number of seeds seated on a
long pedicel with barren scales between them. The whole mass of
seeds and intermediate scales is closely packed into a head, and is
enclosed by a kind of pericarp formed of coherent scales, and
pierced by the micropylar terminations of the erect seeds. Outside
the pericarp, a wain, is an envelope of bracts which have precisely
the structure of scale-leaves in cycads. The internal structure of
the seeds is perfectly preserved, and, strange to say, they are
nearly, if not quite, exalbuminous, practically the whole cavity
being occupied by a large dicotyledonous embryo.
This extraordinary fructification is entirely different from that
of any other known group of plants, recent or fossil, and charac¬
terises the Bennettiteas, as a family perfectly distinct from the
Cycadese, though probably as Count Solms-Laubach suggests, having
a common origin with them at some remote period. The Ben-
nettiteee, while approaching Angiosperms in the complexity of their
fruit, retain a filicinean character in their ramenta, which are
quite like those of ferns, and different from any other form of hair
found in recent Cycadese. Probably the bennettitean and cycadean
series diverged from each other at a point not far removed from
the filicinean stock common to both.
I hope that the hasty sketch which I have attempted of some of
the indications of descent afforded by modern work on fossil plants
may have served to illustrate the importance of the questions
involved and to bring home to botanists the fact that phylogenetic
problems can no longer be adequately dealt with without taking
into account the historical evidence which the rocks afford us.
Before leaving this subject I desire to express the great regret
which all botanists must feel at the recent loss of one of the few
men in England who have carried on original work in fossil botany.
At the last meeting of the Association we had to lament the death,
at a ripe old age, of a great leader in this branch of science, Pro¬
fessor W. C. Williamson. Quite recently we heard of the
premature decease of Thomas Hick, for many years his demon¬
strator and colleague. Mr. Hick profited by his association with
his distinguished chief, and made many valuable original contri¬
butions to palseobotany (not to mention other parts of botanical
science), among which I may especially recall his work, in conjunc¬
tion with Mr. Cash, on Astromyelon (now known to be the root of
Calamites), on the leaves and on the primary structure of the stem
in Calamites, on the structure of Galamostacyhs, on the root of
Lyginodendron, and on a new fossil probably allied to Stigmaria. His
loss will leave a gap in the too thin ranks of fossil-botanists ; but
we may hope that the subject, now that its importance is begin¬
ning to be appreciated, will be taken up by a new generation of
enthusiastic investigators.
Conclusion.
To my mind there is a wonderful fascination in the records of
the far-distant past in which our own origin, like that of our
distant cousins the plants, lies hidden. If any fact is brought
home to us by the investigations of modern biology, it is the con¬
viction that all life is one ; that, as Nageli said, the distance from
man to the lowest bacterium is less than the distance from the
lowest bacterium to non-living matter.
In all studies which bear on the origin and past history of living
things there is an element of human interest — •
“ Hence, in a season of calm weather,
Though inland far we be,
Our souls have sight of that immortal sea
Which brought us hither.”
The problems of descent, though strictly speaking they majr
often prove insoluble, will never lose their attraction for the
scientifically guided imagination.
MEETINGS Of SCIENTIFIC SOCIETIES
Chemical Society, Thursday, May 20. — Professor Dewar,
F.R.S. , President, in the chair. — There was a large and rather
distinguished audience on this occasion, but the meeting as a whole
might be placed in the dry-as-dust category. The first three
papers were by Mr. Holland Crompton, and treated wholly of
The Molecular Characteristics of Liquids.
They were on “ The theory of osmotic pressure and the hypothesis
of electrolytic dissociation,” “ Molecular rotation of optically active
salts,” “ Heats of neutralisation of acids and bases in dilute aqueous
solution.” There was nothing in them of the slightestinterestto even
the most scientific of pharmacists. Mr. Crompton occupied a whole
hour in juggling with letters and figures, and the night being very
hot and dusty, the papers were rather trying to listen to.
—Professor Crum Brown, a former President of the Society,
was present and spoke, and so did Professor Thorpe and
Mr. Pickering. — Dr. Walker gave Mr. Crompton a
few hard nuts to crack, as was evidenced by the latter’s
somewhat weak reply. By the time the reading of these
papers and the discussion came to a close the time was already
twenty minutes to ten, so that it was clear that Mr. Tutton’s paper
on “A Comparative Crystallographical Study of the Normal
Selenates of Potassium, :Rubidium, and Caesium,” and Mr. John
Spiller’s on “ The Platinum-Silver Alloys; their Solubility in Nitric
Acid” must be given in the briefest of abstract. Mr. Tutton’s
paper is in continuation of several others on the same lines, and the
gist of it is that
Rubidium Selenate
in its various properties, such as solubility, axial ratios, refraction
constants, etc., occupies a place intermediate between that of
potassium and caesium. Mr. Tutton’s experiments evidently
were conducted under the greatest difficulties on account
of the hygroscopic nature of the salts, special con¬
trivances in connection with the balances having had to
be resorted to. — Professor Dewar complimented Mr. Tutton
on having delivered his paper in its very essence. Mr. Tutton’s
characteristic modesty and brevity made his subject extremely
interesting. — A few words from Dr. Gladstone brought the matter
to a close, and then, already long past ten o’clock, Mr. Spiller was
allowed to further entertain the loner-suffering audience. However,
what Mr. Spiller said was not dry by any means. If Mr. Spiller
is a brilliant chemist he is also a brilliant comedian, for he kept
the audience, on that hot dreary night, in a continued ripple of
laughter. His paper was an attack on text-book statements with
regard to
The Solubility of Platinum-Silver Alloys
in nitric acid. He took about fifteen quotations from standard
works, and showed beyond a doubt that these statements had
been made without any attempt at verification. Mr. Spiller was
sorry that Dr. Thorpe had just left the room, but he had a “hit”
May 29, 1897
PHARMACEUTICAL JOURNAL.
481
at the Assistant-Secretary’s edition of ‘Bloxam.’ He proves
conclusively that the platinum is not dissolved in nitric acid. —
Mr. Friswell, however, pointed out that the presence of sulphuric
acid in nitric acid might account for the text-book statements, for
the presence of the former acid in the latter was extremely
destructive on platinum.
THE WORLD Op PHARMACY.
- 4 -
BUSINESS MEETINGS.
Western Chemists’ Association (of London), Wednes¬
day, May 26. — Mr. J. W. Taplin, President, in the chair. — The
following paper, by Mr. J. C. Hyslop, was read : —
Some Short Notes on Storage and Pharmacy
Arrangement.
There is a subject that has never yet received the attention which
its real importance merits. Being honoured with an invitation
to address you this evening, I have chosen it for some remarks
which are intended to be but suggestive, and must from the
limited time at my own disposal just at present be very elementary
indeed. Should this present effort be instrumental in
provoking some others with more time, and a larger grasp
of the whole science of the subject, to undertake its further
advocacy, my object will be fully attained, failing which I
cherish a hope of returning to it myself when increased
leisure may be favourable for its more exhaustive treatment :
The climatic conditions of the shop — an interesting study that may
be pursued with pleasure and profit quite as a recreation in the
intervals of a pharmacist’s busy day’s work. The thermal, the
hygroscopic, and the barometric conditions of the shop varying, as
they seem, at first thought, indefinitely, have nevertheless fixed
natural limits of variation, with altitude, latitude, and longitude —
height from floor to ceiling, length from front to back, and breadth
also — specially marked if the door be not in the centre of two
windows, quite analogous to what obtains in the great
world outside with respect to elevation above sea-level, etc.
And as in this latter case such widely different effects
are produced from the most simple of causes, effects
that lie at the centre of all the differences of the flora and
fauna and the anthropological characteristics of the universe
around us, so it needs but the observant eye of a cultured mind —
such as we expect the pharmacist will be characterised by in the
future, even still more than in the past — to discern the ways and
means of preserving in their best possible conditions the thousands
of good things committed to his charge always in readiness to
meet the popular demand, and supply the need of the
“ Wise physician, skilled our wounds to heal,
Who is more than armies to the public weal.”
But, to dig straight into the subject. Which is the dampest part
of the shop ? I mean old-fashioned shops that are, and wall be for
a long time yet, lighted by gas ; perhaps the electric light will
introduce different conditions altogether, but this is now quite out of
my line. In the generality of shops we have going on about mid¬
way between floor and ceiling, all the year round for one-third of
our whole time, the manufacture of HO in the form of very hot
steam which gradually cools as it escapes into the street above our
'heads. In winter time the window glass is so cold that it
•condenses large quantities into liquid, which gives us all some
amount of trouble ; this may, however, be prevented by lighting up
one or two burners in the window first, or better still set going a
Bunsen burner to warm the upper inclosure before lighting up at all.
Whether, however, we adopt these precautions or not we find
always, all the year round, in dry seasons or wet ones, that the
•space under the window -board, where often the gas-meter is placed,
is as cool and damp a position as we could wish for where confec¬
tions of senna, rose, etc., may be kept in lightly-covered jars
almost indefinitely of a proper consistency ready for sale or the
dispenser’s use. And perhaps more important still the extracts —
rhubarb, chamomile, lettuce, etc., always in a fit condition for
pill-building. Certain pill-masses, too, as blue pill and certain
others, keep best in this position ; whilst others, as comp.
rhubarb and Plummer’s pill, must be kept in a drier
place. Of the extracts, too, hemlock and henbane and a
few others must be looked after and nursed a little, leaving
them for a few weeks in one position and then for a few weeks in
another, but with the greater part of one’s stock the golden rule,
•‘A place for everything and everything in its place,” holds good
exclusively. Ordinary spare deal boxes may be utilised for these
purposes, containing the pots just as they arrive from the whole¬
sale houses, with a lock-up box for ext. of aconite, nux. vom.,
belladonna, etc. , ranged above one another from the flooring up¬
wards. Under the counter also is the place for capsules, jujubes,
and confectionery pastilles generally. Lozenges and all hard baked
articles should have assigned to them a higher and a drier place,
not kept in close stoppered bottles, but in boxes or lightly covered
bottles, whence any trace of moisture may be easily dissipated,
instead of being transformed into overheated steam and spoil the
whole mass. This warm dry place is to be found in perfection at
the back of the shop near the ceiling, the influence of the burning
gas over night being shut in till the next morning and not nearly
dissipated during the following day until the need arises for its
repetition. So that a constantly warm and dry climate is here
available all the year round. A small packet of squill bulb, if well
dried at starting, will keep here ready to be rubbed to powder in a
hot mortar whenever a little powdered squill is required. English
honey, procured in the liquid state from the bee-keeper, will here
keep liquid through the severest winter if simply left alone as
much as possible, i.e., very gently handled when the need arises.
And whilst speaking of honey let me just add, in passing, that if
in the forthcoming B.P. there is retained that awful monstrosity
of ancient ignorance, “ Mel Despumatum,” it will prove one posi¬
tive disgrace to the pharmacy of the Victorian era. Honey is
rudely spoiled by being melted down and strained. Nor is it
necessary in any sense to do so. The same remark
holds good as to asafeetida, it spoils the drug. Honey
will clarify itself if simply left alone; if wanted to “set,”
put it in a cool place, and “setting” will soon set in ; if wanted
to be kept in the liquid state, which is a much better condition for
it, keep it carefully and as undisturbed as possible in a warm, dry
place. Leeches will never go quite out of date, in spite of all the
mess .and muddle they are subjected to and the sophistry that has
been written about them. Put them into a wide-mouth bottle half
filled with water tied over with a piece of flannel and covered round
with two or three folds of corrugated paper to exclude the light
and prevent accidental fracture. Place in a cool dry corner and
very carefully examine once or twice a week, and never change the
water until there is a faint/ smell of something going wrong.
Never mind the abundant clots of dark-looking matter. If this
dirtiness does not mix with the water all will go on best by being
left alone. It would seem as if good leeches want simply to sleep
away their lives in darkness, peace, and quiet till man — “that all-
depending lord ” — requires the assistance that they alone can render
him. For the storage as well as the manufacture of ointment bright
tinned iron vessels are far more suitable than the earthen ointment-
pot, the glaze of which soon goes wrong and gives a bad character
to the whole of the contents. To sum up these desultory remarks,
let me say that lime-water must be kept on the floor, cool ; glacial
acetic acid and liquefied carbolic acid near the top ; most syrups
keep better in a warm place, syrup of poppies specially excepted ;
powdered vegetable substances do best in pots with tin covers.
Distilled water in bright glass coppers at the top of the shop without
corks, if not glass stoppers then tie over with clean paper and
this protected by a tin cover. Pills in shallow wooden or paper
trays so as not to lie at top of each other ; Glauber salts and any
other efflorescent crystals down under the window board in sound
paper packages. We sometimes hear of a chemist having to stay
in his shop and wait for customers, a statement that ought to Retaken
up by our old friend “ Punch” : certainly that misery was never mine.
“ Stone walls do not a prison make,
Nor iron bars a cage.”
Then why should a chemist’s shop ? Depend upon it, sir, that as
the fruits of pharmaceutical education and general culture become
more diffused these groanings will cease. There is a perfect cosmos
all about him from which a pharmacist may be ever choosing for
himself subjects of beauty and interest connected with his essential
avocation, and which dove-tail in with it in thousands of ways,
tending to make his whole career one of delight and happiness, the
delight and happiness that ever accompanies the truly cultured
mind in every station and condition of life.
482
PHARMACEUTICAL JOURNAL.
[May 29, 1897
Nottingham and Notts. Chemists’ Association, Wed¬
nesday, May 26.— Councillor R. Fitzhugh, President, in the
chair. — This was the annual meeting of the Association, and the
first business was the
Election of Officers.
The following officers were re-elected for the ensuing year : —
Councillor R. Fitzhugh (President), Mr. J. Wilford (Treasurer),
Mr. A. Eberlin (Secretary). Mr. A. Middleton vacated the office
of Vice-President in the ordinary course, and Mr. F. R. Sergeant
was elected to the position. The following members were elected
on the Council by ballot : — Messrs. C. A. Bolton, E. Gascoyne,
A. Middleton, R. Beverley, W. Gill, A. E. Beilby, S. Cook, and
T. Mason.
Annual Report.
The Secretary then read the annual report, which spoke of a very
successful year of progress. After referring to the various meetings
held during the year, including Mr. Howie’s lecture, the annual
dinner, and the special meeting to discuss the proposed altera¬
tions in the bye-laws of the Pharmaceutical Society, the report
proceeded — •“ Turning now to the important subject of the educa¬
tion of the associates, your Council is able to record a very success¬
ful year. Botany and practical dispensing are the two subjects
taken during the past year, and the arrangements previously held
with the college authorities have been continued. In the former
subject (botany), held under the tuition of Professor Carr and Mr.
A. E. Smith, B.Sc., thirty-one students joined in the first term,
twenty-seven in the second, and seventeen have already joined in
the current term. Mr. Sergeant, who has for some time past con¬
ducted the class in practical dispensing, resigned, and the Secre¬
tary undertook to take his place with the assistance of Mr. Turton,
an associate of the Association. Eleven students joined and the
attendance was very good, the progress also being satisfactory.
At the conclusion of the term Mr. Sergeant conducted an
examination and awarded first place to M. Chambers, second to
C. E. Bell, and third to A. Watson. The membership of the
Association stands as follows : — Members, 49 ; honorary ditto, 2 ;
associates, 33. Your Council records will regret the loss by death
of two members, viz., Mr. R. Patchitt, and Mr. John Marshall,
the respected representative of Messrs. Hearon, Squire, and Francis. ”
—The report was adopted on the motion of Mr. Warriner,
seconded by Mr. S. Cook.
Financial Statement.
Mr. Wilford next presented the treasurer’s report, which showed
that the income during the past year was £100 14s. 3d., including
a balance from the previous year of £47 6-s. 3d. Thirty,
nine members had paid their subscriptions. After meeting
all liabilities there remained a balance at the bank of £34 15s. 1 d.
and £6 6s. 3c?. in hand, making a total of £41 Is. 4c?. — Mr.
Radford proposed, and Mr. Warriner seconded, that the report
be adopted, the resolution being agreed to. — Mr. Bolton said this
year had been a very special one in connection with the Benevolent
Fund of the Pharmaceutical Society, which, he was pleased to
know, the chemists of the town had supported very well by their
subscriptions during the year, and seeing that this was a special
year in connection with that Fund, he thought it would be a very
proper thing if the Association gave a donation of £10 towards the
Fund out of the balance in hand. They all knew how well that Fund
was distributed, how needy were the recipients who were dependent
upon it, and how the money which was given year by year to
the Fund was always devoted to the special object for which it
was given, namely, the relief of the poorer members of the trade.
He therefore proposed that £10 be paid to the Fund out of the
balance in hand.— Mr. Gascoyne seconded, and the resolution,
after the amount had been amended to £10 10s., was unanimously
adopted. — The Treasurer was instructed to forward a cheque for
the amount forthwith.
Address by the President.
The President then made a few remarks on matters generally con¬
nected with the Association. He said he was pleased to see so many
present. The fact that there were not more was no doubt owing
to the fact that those absent had sufficient confidence in those
present to conduct the business of the Society to their
satisfaction. He was very pleased that a great many of those who
were on the Council formerly had been elected that night, and he
thanked Mr. Warriner personally for retiring in favour of Mr.
Mason, who was a most genial man, and had done a great deal far
the Society, perhaps not in an educational point of view, but from
the convivial aspect. He felt grateful to them for re-electing him
President, although he thought the time had come when some one
should be found to succeed him. He had filled the office for many
years, and also had passed through the other offices of the Asso¬
ciation. But it seemed to him that it was still their wish that he
should remain President of the Association, and while he held the
office he hoped it would be his endeavour to do the best he could for
the Society. Referring to Mr. Sergeant’s election as Vice-Presi¬
dent, he said they all welcomed the election, as Mr. Sergeant
was, he might say, an old student of the Association. Nothing
gave him (the President) greater pleasure than to see the younger
members of the Association occupying its offices. It had been his
great pleasure to do all he possibly could for the advancement of
the younger members of the Association, and he hoped it would
be deemed by the Council of the Association to be its duty to do
all it possibly could in the interests of the younger members. He
was quite sure that the Pharmaceutical Society would do all that
was possible for the advancement of the trade at large. Referring
to the recent discussion on the proposed bye-law alterations, tho
President said there was no doubt that the examinations now were
much more severe and strict than formerly. He did not object to>
that, but he did wish they could derive some greater advantage
than they did in the matter of protection to their trade. The only way
he saw to that end was for members of the Pharmaceutical
Society to elect gentlemen on the Council who would carry out
their views more than was done at the present time. It was all
very well to say that it was inconvenient for country members to
attend, but he was sure they would agree with him that gentlemen in
London did not know sufficient about the country trade, and were
therefore not able to legislate for it. Nottingham was pointed to
in the provinces as having a good Association and taking a leading
part, and he hoped it would continue to do so, and with their
support and the support of the Council which had been elected that
night, he hoped he should continue to do any service he possibly
could for the Nottingham and Notts. Chemists’ Association. — Mr.
Sergeant, Mr. Wilford, and Mr. Eberlin also said a few words in
returning thanks for their election.
The Storage of Benzoline.
A discussion subsequently took place on the new regulations issued
by the Nottingham Corporation with regard to the storage of ben¬
zoline. — Mr. Lumby said he had complied with the requirements
of the Markets and Fairs Committee, and had been compelled to
excavate a pit in the yard of sufficient depth to carry a galvanised
iron tank and put up a brick structure covered with a wooden
roof, which in its turn was required to be surmounted by
galvanised iron or slates. He had been visited by the inspector
and three town councillors. What surprised him most was that
one of them, who was a medical gentleman, and, of course,
.should know something about the nature of benzoline, was
careful to point out that he must seek to avoid any leakage
from the tank, because if the tap leaked and the liquid soaked into
the ground there would be a terrific explosion. That was only one
of the absurd provisions those who sold benzoline had to comply
with. Unlicensed persons were not allowed to keep ben¬
zoline in quantities of more than a pint. Mr. R. Widdow-
son said the dimensions of the trade had shrunk to such
an extent, that it was really not worth while to store ben¬
zoline. Another absurd regulation was that which required a tray
to be placed under the cistern, which was like asking them to put
a tray under a bottle of ether. — The President said they would,
agree with him that benzoline had been stored in a very dangerous-
manner, as the recent explosion in Nottingham proved, and he was
quite sure they would agree with him that some safeguard ought-
to be put on the storage of the oil. Whether the Committee of
the Corporation, however, had issued wise regulations was not for
him to say, but he did not think the Town Council was to blame
in putting some stringent regulation upon the storage of this most
explosive spirit. The Town Council had only one object in Anew — the
protection of the public. — Mr. S. Cook and Mr. Warriner having
spoken on the subject, Mr. Bolton proposed that the following
gentlemen act as a deputation to the Markets and Fairs Com¬
mittee to point out what they considered ought to be amended in
the new regulations : — Messrs. Widdowson, Lumby, S. Cook,
Wilford and Warriner. — The President said he would be willing
to introduce the deputation to the Committee. — The meeting then
terminated with a vote of thanks to the President for occupying
the chair.
May 29, 1897]
PHARMACEUTICAL JOURNAL.
483
LETTERS TO THE EDITOR.
The Council Election.
Sir, — The result of the recent election of Council is particularly
Instructive — instructive in exemplifying the fickleness and ingrati¬
tude of the electorate, but opportune in demonstrating the danger
which may accrue from associations professedly formed for the
protection of specialised interests. After over fifty years of phar¬
maceutical education, it is a somewhat humiliating reflection that
some 2000 members of our craft (three-fourths of whom are alleged
to be subscribing members of the Society) should fail to see any¬
thing derogatory in discussing and arranging with grocers, oilmen,
and ironmongers the prices at which medicines shall be supplied
to the public. It is quite possible that by far the larger number
of those who have allowed themselves to be ranged under “the
banner with the strange device ” may have been guided more by a
sympathetic regard for those suffering acutely from senseless
competition rather than from any idea that an association playing
so low down could effect much for the chemist and druggist. Be
this, however, as it may, we are now forewarned to this extent, that
not only have those been threatened with difficulties in obtain¬
ing supplies who could not conscientiously give direct support
to this movement, but we see further that, should there be any
■considerable expansion of this “ unholy alliance,” the future
Council of the Pharmaceutical Society may be elected, dominated,
and its policy determined at the sweet will of the Grocers’ Federa¬
tion.
285, Brockley Road, S.E., May 22, 1897. Leo Atkinson.
Sir,- — I beg to present my earnest thanks to all who contributed
to my total of 1112 unsolicited votes at the late Council Election,
and to add that I feel perfectly satisfied with the result. The fact
that at the dictation of an outside organisation, having for its
chief object the cultivation of quack medicine trade, men who for
many years have been the life and soul of pharmaceutical progress
are placed near the bottom of the list, must surely awaken the
attention of many loyal adherents of the Society, who this time
have refrained from voting, and they should see to it that the
intended contumely is wiped away upon the first opportunity.
Marylebone, N. W., May 24, 1897. J. C. Hyslop.
The Proposed New Bye-Laws.
Sir, — It is with great pleasure indeed that I approve of the wise
action taken by the Pharmaceutical Council, both as regards the
Preliminary and Minor examinations, and think that every educated
and unselfish pharmacist ought to support the decision of the
Pharmaceutical Council ; otherwise he has no love to see his pro¬
fession placed upon a respectable standing. In fact, as regards
examination matters and decisions which tend to the advancement
of our profession educationally, socially, or financially to enrich
our corporation, we ought always to approve of them as medical
men generally approve of the steps usually taken by their
colleges and medical council for bringing their profession and
curriculum to the standard of the time.
Aux Cayes, Haiti, May 2, 1897. E. L. N. St. Cyr.
The Brentford Lime Cream and Glycerin Case.
Sir, — I think Mr. Bevan would have been better advised had he
left his scientific reputation in the tender care of the Brent¬
ford magistrates. He certainly is not likely to improve it by
rushing into print over this case. Mr. Bevan first certified that no
glycerin was present in the compound. He now admits (as also
at the last hearing) that he found glycerin present in traces. It
seems to me, sir, tbis puts the case in a serious light. If glycerin
was found to be present in the sample received by Mr. Bevan, by what
right did he sign a certificate to the effect that no glycerin was present?
In order to defend his certificate, after three analysts had certified
glycerin was present, Mr. Bevan stated that a separation had
occurred, and that the glycerin had settled down with the watery
portion to the bottom ! By a singular chance Mr. Bevan had
received the top portion containing, I presume, practically nothing
but oil, and the Chairman, without taking evidence on the point,
threw over the inspector by stating that the samples were taken
without the bottle being first shaken. As a matter of fact, as far
as that point is concerned, the inspector did his work properly, and
this is borne out by the figures of the Somerset House analysts, who
certified they found 50 p. c. oil and 50 p. c. watery portion, correspond¬
ing withmyrecipe, which contained just those proportions. Mr. Bevan
refers to Mr. Conroy’s evidence, which “ merely went to the length
of showing . . . glycerin present,” and his own duty was neither
more nor less ! As to the amount of glycerin present, is a public
analyst to assume to himself the right to dictate what amount of
any ingredient should be present in a private recipe for an
unofficial compound? In the case in question the amount of
glycerin present is sufficient to answer its purpose in a hair wash
without decomposing the preparation, the recipe forming an
absolutely stable emulsion. I could touch on other points, but I do
not think it would now rectify the injustice done me in depriving
me of my legitimate costs.
Chiswick, May 25, 1897. J. W. Webber.
“A Royal College of Pharmacy.”
Sir, — As one of the younger generation of chemists, and as one who
has qualified under the Pharmacy Act and believes in the many bene¬
fits derived from its working, not only as regards education and
competency, but also as providing for the public safety, I cannot
refrain from commenting upon the sensible suggestions made by
Fyton in your issue of the 22nd inst. As the Pharmaceutical
Society is very largely supported by Associates, and is now — and
rightly too — proposing to give Associates the same privileges as
Members, it would be well in the interests of the Society if the
President and officers would do their utmost to get the necessary
powers granted at the same time, so that all chemists upon the
Register connected with the Society could hold and enjoy some more
fitting title, such as has been suggested by Fyton — Member of the
Royal College of Chemists. Would there not then be more chemists
within the fold of the Society ? To my mind the Pharmaceutical
Society has done eminent service to the State, by compelling all
those who handle poisons and display the title of chemist to first edu¬
cate themselves in such a manner so that their businesses may be
carried on under competent qualified supervision for the safety of the
public. Surely when the Society has done so much for the proper
training and education of chemists generallly, it is worthy of some
official recognition by the State, and the distinguished title of
“ Royal ” would be well merited. In every succeeding Register
of Chemists and Druggists the numbers therein of trained and
educated men will increase, and I think now would be a fitting
time to endeavour to raise the status of the Society, not only in
the eyes of the public, but among the medical profession, and last
but not least, among the chemists themselves. I trust this
subject may yet receive the attention it deserves, and that some
more eloquent and influential person will take the matter up is the
earnest desire of
May 24, 1897. A Young Chemist (96/4).
ANSWERS TO QUERIES.
Fern. — Lastrea spimdosa. [ Reply to Associate. — 95/ 11.]
Plant. — Pedicular is sylvatica. {Reply to Minor Student. — 95/20.]
Fern. — Apparently Osmunda regalis, so far as can be judged
from such a fragmentary specimen. {Reply to T. E. P. — 95 22.]
British Medical Association. — The membership of the Asso¬
ciation is, we are informed, limited to qualified medical prac¬
titioners. {Reply to A. R. — 95/42].
Tonic Species. — Four mixture appears to consist of sarsaparilla
root and small gentian root, incised and covered with ‘ ‘ composi¬
tion powder.” {Reply to W. H. — 94/29.]
Essence for Ginger Wine. — Soluble essence of ginger, 4 fl. ozs. ;
soluble essence of lemon, 2 fl. ozs. ; oil of sweet orange, 5 minims ;
tartaric acid, J oz. ; burnt sugar, 2 ozs. Mix. If not pungent
enough for your purpose add to above capsicine, 5 grains.
{Reply to W. W. — 95/8.
Books for the Retail. — Yes, a retail pharmacist cannot afford
to be without Squire’s ‘ Companion ’ ; in fact, the more complete
your reference library the more effectually and comfortably will
you carry on your business. Doubtless new editions of the works
you mention will appear soon after the issue of the new B. P. The
U. S. Dispensatory is an extremely valuable work of reference, but
you cannot do without the others. {Reply to W. W. — 95,8.]
484
PHARMACEUTICAL JOURNAL.
[Mat 29, 1897.
Chromo-Prints. — We are informed by a correspondent that these
prints can be obtained from Messrs. Greiner and Co. , 10 and 12.
Milton Street, Finsbury, E.C. [Reply to F. H. S. — 94/45.]
Bending Brass or Steel Tubes. — According to a correspondent
of the Chemical News, cycle makers habitually use resin for filling
in steel tubes up to one inch diameter, prior to bending them.
[ Reply to Spatula. — 91/13.]
Extract of Malt and Oil with Hypophosphites. — Calcium
hypophosphite, 30 grains ; sodium hypophosphite, 60 grains. Rub
down to a fine powder and then quite smooth with glycerin,
2 drachms. Mix with malt extract, 4 ounces, and gradually stir
in cod-liver oil, 1 ounce. Flavour with a trace of bitter almond or
cherry laurel water. [ Reply to W. W. — 95/8.]
Liquor Caulophyllin et Pulsatilla; Co. — We cannot pretend
to give you any imitation of proprietary articles. You can dis¬
solve the resinoid bodies in a little solution of potassa and soda,
and then dilute them down with a menstruum of distilled water,
3 parts, and rectified spirit, 1 part. We do not advise you to
imitate other people’s specialties. Try something original of your
own. [Reply to Volumetric. — 95/4.] *
Aqua Gaultheri.e. — Doubtless a saturated aqueous solution of
oil of wintergreen was intended to be used, unless it was some
private formula. We do not find any official formula for aqua
gaultherke. Perhaps some reader acquainted with Canadian
pharmacy can enlighten us and you regarding the accepted formula.
There is no Canadian Pharmacopoeia. The B.P. is the official book,
but the U.S.P. is widely followed. [Reply to C. T. J. — 94/10.]
Keeping Properties of A.C.E. — As far as we know, A.C.E.
prepared from pure ingredients, properly secured and kept in the
dark, will keep indefinitely. There is no reason why it should
not. If these precautions have been observed we should doubt if
it is possible that it can be less effective as an ancesthetic after
being kept for more than a week. The definite formula given in
the 1 Extra Pharmacopoeia ’ is certainly to be preferred to the old
one. [Reply to Dispenser. — 95/14.]
Petroleum Emulsion. — White vaseline, 24 ; powdered gum
arabic, 6 ; powdered gum tragacanth, 2 ; tincture of quallaia, 2.
Rub down smooth together in a hot mortar, then add at once warm
water, 16, and rub vigorously until a perfect emulsion results ;
then gradually add with constant stirring a solution of calcium
hypophosphite, 1 ; sodium hypophosphite, 2 ; elixir of glucide, 1 ;
warm water, 20. Keep stirred constantly until quite cold. Flavour
with orange, vanilla, or winter-green. [Reply to Oleum. — 94/41.]
Gravimetric Determination of Invert Sugar. — Beetroot
sugars, as a rule, contain very little invert sugar, so it is necessary
to make a strong solution, say, 20 grms. in 100 C.c. of water.
Twenty C.c. of Fehling’s solution is boiled and a few C.c. of the
sugar solution is run in ; boiling is repeated and more sugar added
until only a faint blue colour persists after boiling ; the number of
C.c. of sugar solution used is noted ; the red precipitate of cuprous
oxide is collected, washed, dried, and burnt into CuO. Every
gramme of this = 0 ’4535 invert sugar. You specify a gravimetric
process, but in actual practice you will find the optical method or
the volumetric process far more rapid convenient and accurate.
[Reply to J. W. — 94/40.]
Emulsion of Cod-Liver Oil. — Your formula is not a good one.
Glycerin and arrowroot are both undesirable ingredients. The
following will give you a simple gum emulsion, which will serve as
a basis : — In a dry mortar put powdered acacia, 1 part, and rub it
smooth with cod-liver oil, 4 parts ; then add at once water, 2|,
and emulsify thoroughly, then gradually add water or flavouring
to make 8 parts ; if you require a thicker emulsion than this, in¬
crease the amount of acacia ; if thinner, gradually add more water.
A good emulsion with condensed milk may be made as follows
Cod-liver oil, 8 fluid ounces ; condensed milk, 6 ounces by weight ;
tincture of quillaia, 2 fluid drachms ; water to produce 16 fluid
ounces. Rub the milk with the quillaia, and gradually add the
pil ; then slowly mix in the water. Flavour the emulsion to
taste. [Reply to H. H.— 95/6.]
Bolton’s Collodion Emulsion. — Many formulae have been given
by Mr. W. B. Bolton for collodion emulsion, for he was with Sayce
the originator of this particular method of working. The latest
formula given by him is the following : — Absolute alcohol,
9 fl. oz. ; methylated ether (s.g. 720), 11 fl. oz. ; pyroxylin, 100-
120 grs. ; double bromide of cadmium and ammonium, 200 grs.
Dissolve the bromide in the alcohol in the bottle in which
the collodion is to be made, and when dissolved put in
the pyroxylin, which should be thoroughly dried, and.
pulled out into loose tufts. When thoroughly saturated
add the ether, and on shaking, the cotton should imme¬
diately dissolve. Set the collodion by for at least three days
to allow any sediment to precipitate, decant in preference to
filtering. To every 10 ozs. of the above collodion add 150 grs.
of silver nitrate dissolved in 75 minims of distilled water by the
aid of heat. Not more than this quantity of water must be used
warm 1 oz.. of alcohol, and add to the silver nitrate, a few drops at a
time, and boil in between each addition so as to keep the silver in
solution. Now in the dark room pour into a measure 7 ozs. of the
collodion as above to be sensitised, and add the silver solution
slowly, and gradually stirring all the time. Be very careful not
to add the silver too quickly ; allow the emulsion to stand for hair
an hour, and then add 3 ozs. of the bromised collodion ; shake well,
and add 15 grs. of the double bromide of cadmium and ammonium.
The emulsion now only requires filtering through cotton wool of
sponge to be ready for use, and it will then keep for some months.
[Reply to C. G.— 93/25!]
CORRECTION.
First Examination Results. — In the list of First examination
results published in the Journal of May 15, for “ Thomas, William
John, Llanelly,” read “ Thomas, William John, Tenby.”
OBITUARY.
Holland. — On May 2, Walter Holland, Chemist and Druggist,
Nottingham. Aged 58. Mr. Holland had been a member of the
Pharmaceutical Society since 1870.
Blackshaw.— On May 8, Thomas Blackshaw, Pharmaceutical
Chemist, late of Burslem. Aged 77. Mr. Blackshaw had been a
member of the Pharmaceutical Society since 1845, and was regis¬
tered as a pharmaceutical chemist on July 1, 1852. He was for
many years the Society’s Local Secretary and a generous subscriber
to the Benevolent Fund. He was also an original member of the
Pharmaceutical Conference. He held the office of Gas Examiner
to the Corporation of Burslem, and was highly esteemed by his
fellow townsmen. He was a thorough pharmacist and a clever
scientist, his favourite studies being chemistry and botany, and
although a strict disciplinarian in business, he was a kind-hearted
master. He occupied many posts of honour and trust in the town.
For the past few years he had not taken an active part in the
business of a pharmacist, but lived at Alsager in retirement.
Morris. — On May 13, Thomas Morris, Chemist and Druggist,
late of Farnworth, Lancs. Aged 62.
Ryder. — On May 14, James Fielding Ryder, Chemist and
Druggist, West Gorton, Manchester. Aged 51.
Raynor. — On May 18, Alfred Raynor, Chemist and Druggist,
Hull. Aged 50.
Savage.— On May 18, Fred George Savage, Chemist and
Druggist, Nottingham. Aged 36.
Cardwell. — On May 20, James Cardwell, Chemist and Drug¬
gist, Wakefield. Mr. Cardwell was one of the representa¬
tives of St. John’s Ward in the Wakefield City Council, and
in November last he was selected to act as Deputy-Mayor. He was
for several years one of the churchwardens at the cathedral, and
for a long period he had been officially connected with the Wake¬
field Great Court Leet.
Nicholls. — On May 21, John Nicholls, Chemist and Druggist,
Weymouth. Aged 73.
Maitland. — On May 24, at Plymouth, Harriet, the beloved wife
of Samuel Maitland, retired chemist. Aged 72. Golden wedding,
July 31, 1897.
COMMUNICATION S, LETTER S, etc., have been received from
Messrs. Alcock, Atkinson, Bennett, Bennion, Brown, Doubleday, Durrant,,
Edwards, Elliot, Elms, Flatters, Gall, Gibson, Giles, Goldby, Griffiths, Hill,
Hinkley, Hyslop, Johnson, Jones, Matthews, Merson, Morris, Nightingale, Nops,
Pearson, Reeve, Reynolds, Roper, Rudd, Shepherd, St. Cyr, Turner, Watson.
June 5. 1897]
PHARMACEUTICAL JOURNAL.
4*5
A SIMPLE MICROTOME FOR BIOLOGICAL WOiK.
BY ABRAHAM FLATTERS.
The microtome originally designed by me ( vide Ph. J. [3], xxiii. ,
1057) was very simple in construction, but I now employ it in an
improved form. It is made entirely of brass and cast in four
parts ; the tube or well measures 3 inches by 1 inch internally , and the
spindle is of the same length, the screw having twenty-eight threads
to the inch. The
spindle is graduated
to give the required
thickness of section by
a series of discs 3
inches in diameter
and inch thick,
these being notched
as shown in the right
and left elevations
(Figs. 1 and 2). In the
notches works a gradu¬
ating spring, and by
its clicking arrange¬
ment I am enabled to
obtain a uniform
series of sections of
exactly the same
thickness. In my work
I use three of these
discs, which can be
quickly changed by
means of the clamping
nut at the base of
the spindle. One disc
has its circumference divided by seventy-two notches, and when
by its means the spindle is moved to the extent of one notch only
I am enabled to obtain a section the inch in thickness.
This disc I use only when cutting textile fibres. A second disc
is divided into fifty-four parts, and thus gives a section a little
over x inch in thickness. The third disc is divided into forty-
three parts, and gives a section a
little over inch in thickness,
this being the most useful for
general purposes, as when moved
two notches it gives a section the
^(7 of an inch in thickness, which
is about the average that most
botanical objects can be cut to.
The object carrier is of the
same diameter as the tube and
£ inch thick. This serves for all
general purposes, but when it is
required to cut sections of very
small objects, and those have to
be cut in a special direction, it is
necessary to have a cork carrier
placed on the usual brass one.
This special carrier should be
about J inch thick and tapered a
little at the top to enable it to be
worked up through the bevelled
aperture of the razor plate. The
object to be cut (say, a grain of wheat) should be held in
position by pins being stuck into the cork carrier on each
side of it, and when the imbedding medium poured over it is
Vol. LVm. (Fourth Series, Vol. TV.). No. 1406.
set, the pins should be removed. The razor plate is 4f inches
by 2| inches by yV inch, with an aperture at the under surface
of the same diameter as the tube, and tapering towards the upper
or cutting surface to H inch. This enables the object along with the
imbedding mass to be firmly held in position as it is gradually
screwed up. The razor plate is attached at one end to the table
clamp by a stout screw, as shown in section (Fig. 3), and when in use
the other end is clamped to the headstock by means of a swinging
clamp, which is attached to the under side of the razor plate and
held, when in position for work, by a milled head and screw. This
arrangement is seen in the left elevation, where the razor plate is
486
PHARMACEUTICAL JOURNAL.
[June 5, 1897
shown swung on one side. When the required number of sections
have been obtained and it is necessory to remove the uncut
material, the spindle is first lowered a few turns and
the object pressed down. The razor plate is then re1 eased
by the clamp, swung to the right, and the uncut material
removed. The table clamp is attached to the tube, as seen in the
right elevation, the entire instrument being secured by a stout
grip. The graduating spring fits into the upright limb of the
table clamp, and is held in position by a clamping screw, as seen
in the sectional view.
In addition to the instrument as described, I use for special
work an “oblong top,” which fits on to the top of the microtome,
and is held in position by a series of clamps and the two milled
heads shown in the illustration (Fig. 4). The aperture of this plate is
£ inch wide by 1 J inch long by inch deep. The carrier for this fits
into the tube of the microtome, and is moved upwards by the ordinary
spindle. The aperture, like that of the ordinary razor plate, is
bevelled t'b inch, as shown in the diagram representing the under¬
side view. This oblong top is required when it is necessary to cut
longitudinal sections of such objects as the mouse and other similar
objects which cannot be imbedded in the ordinary tube of 1 inch
diameter. The imbedding medium I use is the ordinary hard
paraffin, this being applicable for all purposes, except where it is
necessary to permeate the object in order to retain all the parts
in their natural position. For the latter purpose I use Schering’s
celloidin. In a subsequent note I propose to describe in detail my
method of preparing and cutting dried capsicum fruits, in the
hope that the information may prove of value to pharmacists and
students interested in the histology of crude drugs.
A LONDON RESIDENTIAL CLUB.
For the young man of moderate means who arrives in London
to study for a profession or to enter on the duties of a “ situation ”
of one kind or another, an initial difficulty is the selection of a
domicile suited to his circumstances and tastes. Coming, perhaps,
from a cheerful home under the parental roof, he wishes for some¬
thing more than shelter from the elements ; he looks for comfort,
sociability, means of relaxation, and, if he be destined for a pro¬
fession, a place where he can read and study undisturbed. In a
general way, his choice of domicile is pretty well restricted to two,
the lodging-house and the boarding-house. Let us begin with
lodging-houses. They are easily accessible, and indeed, in their
case the supply quite exceeds the demand. But even where, besides
decent accommodation and attendance, the landlady is obliging
and honest — there are many who are neither — life in a London
lodging-house can have few attractions for the youth whom we
have in our eye. Its solitude is apt to become wearisome and
depressing. For his meals, with the exception, perhaps, of break¬
fast, the lodger must, in most cases, go out of doors in all weathers,
and often for a considerable distance. He has no society, no
opportunities of recreation within doors.
In some respects the boarding-house is preferable to the lodging-
house, but it has drawbacks peculiar to itself. One is that
though the boarder’s meals are furnished him “at home,” so to
speak, he must, being charged a fixed sum for board, pay for them
whether he takes them or not. The hours for them are fixed, as
well as the payment for them. If from indisposition or to keep
an engagement to visit friends, or to make a little excursion, he is
absent from any meal or meals, he has to pay just as if he had
been present, and as no provision is made for meals at other than
the stated hours, if he satisfies his appetite outside the house, -he
has to pay twice for what he has had only once. The boarding¬
house, unlike the lodging-house, does certainly offer society. But
the members of it have not been chosen by the newly-arrived
-inmate. He must take them as he finds them, and meet them
constantly at meal-times day after day. If they are uncongenial
or some of them make themselves disagreeable, the victim can only
escape by going elsewhere, perhaps to meet the same fate.
Between the solitude of the lodging-house and the society of the
boarding-house it is too often only a choice of evils.
London abounds with clubs and club-houses. In any of them
there is society of the smoking-room kind, but it is casual and fit¬
ful ; few friendships or intimacies are ever formed at an ordinary club.
Moreover, a desirable club is not easily accessible. Our young friend
may have to wait some time before being elected, if elected at all,
and as we are supposing his purse to be only moderately well
furnished, the entrance fee and the yearly subscription, with the
charges for meals, are beyond the means of most of those for whom
we are writing. There may be some respectable clubs where the
comforts and agreeable accessories of the great clubs, though on a
smaller scale, are to be found within the reach of such as have
to study a rigid economy. But at the very best, a club is not a
home. At a certain hour you must turn out of it, and our imaginary
young man may have a long distance to traverse before he reaches
his modest lodging in some unfashionable quarter remote from
club-land. Above all, while at a club you may read newspapers
and periodicals, you cannot study with your law-books or your
medical books around you.
The ideal domicile for our young friend would combine the com¬
forts and enjoyments of a good club, and its perfect freedom as
regards meals and meal-times, with that feeling of home for which
the tenancy of a permanent bed-room in the same establishment is
indispensable — a home in which he could write and read and
study as if he were in his own house, where he could have society
or solitude as he was disposed, where the means of recreation and
amusement would be as ample as in an average London club-house,
where the resources of a restaurant would be offered him, and last,
not least, where all this would be within the reach of those with very
modest means at their disposal. London ought to be dotted with such
establishments, and that the programme now sketched can be
carried out with financial success on the part of the capitalist and
with satisfactory results to the inmates is demonstrated by the
existence and history of the Hampden Residential Club, Phoenix
Street, N.W., which, it may be hoped, will not long remain, as it
is at present, unique of its kind.
This Club has existed for twelve years, and its commercial pros¬
perity has steadily increased. To begin with, it contains sixty
“cubicles” at 7s. 6 d. a week, and some 140 furnished bed-sitting-
rooms, ranging from 8s. 6 d. a week to 13s., those at medium prices
being the great majority. In all cases these payments include an
excellent service of baths, hot and cold, boot-cleaning and bed-room
lights, a number of which are electric. Two large club-rooms of the
ordinary kind, very comfortably furnished, in both of which smoking
is allowed, are supplied with newspapers, periodicals, a tolerable col¬
lection of books, chess, and draughts. There is also a card-room super¬
intended by a whist club — in this the stakes played for are very
moderate — and an excellent billiard- room. One of the most notice¬
able features of the establishment is the Study, where members can
read and write in perfect silence and tranquillity, the conversation
rife, of course, in the other rooms, being prohibited here. Once a week
there is a discussion on some literary, political, or social question
in which any member or friend introduced by him may join, and
which is well supported. There are frequent smoking concerts, in
which vocal, instrumental, and other entertainments are given
by members and their friends. Members may be visited by and
hospitably entertain lady as well as gentlemen friends in a
reception room set apart for the purpose. Gentlemen friends may
at all times be the guests of members in the ordinary rooms. In
front of the building and hidden on all sides from the outside
world is a lawn-tennis court, flanked by a larere hall which is used
as a gymnasium by day, and sometimes at night for concerts and
lectures.
To come now to the provision made for the inner man, break¬
fasts are served from 7.30 a.m. onwards, hot luncheons and dinners
from 1 to 2.30, and dinners again and hot suppers from 6 until
9 p.m. But be it noted that at any minute from 7.30 in the morn¬
ing to 12.30 at night an adequate meal may be obtained of coffee,
tea, cocoa, cold meats, sandwiches, cold fish, sausages, etc., etc.,
with or without beer, wine or spirits. Nothing has to be paid
for that is not actually consumed or ordered. The general tariff
is rather below than above that of an average restaurant.
Among the nearly two hundred members of the Club, there are
of course many young men ; but there are also many seniors,
bachelors and widowers, who prefer the Hampden Club to the
lodging-house and the boarding-house. Law, medicine, art, pictorial
and musical, literature, the Civil Service, commerce, engineering,
practical science of various kinds are represented, both among
the younger and the older members of the Club. Nowhere else
that we know of can a young man live at once as economically,
agreeably, and instructively, and a man of any age must be
singularly fastidious if among so many fellow-members of diversified
tastes and occupations he does not find congenial companionship.
All that is needed for the further development of the usefulness
of the Hampden Club is the appointment of a consultative com¬
mittee chosen from the more experienced of the members to give
suggestions and advice to the directors, who represent the pro¬
prietary alone.
June 5, 1897]
PHARMACEUTICAL JOURN AT .
487
BRITISH PHARMACEUTICAL CONFEFENCE.
SUBJECTS FOR PAPERS.
The annual meeting of the Conference will this year be held at
Glasgow, commencing on Tuesday, August 10, and authors
are specially requested to send the titles of papers they
intend to read as early as possible, addressed — “ The Hon.
Gen. Secretaries, British Pharmaceutical Conference, 17,
Bloomsbury Square, London, W.C.” The subjects will then be
publicly announced, and full interest will thus be secured. All
manuscripts of papers should be in the hands of the Executive
Committee at least ten days before the meeting, and as much
earlier as possible. Papers sent sufficiently early and accepted by
the Committee will be put in type before the meeting, and after
the proofs have been revised, copies will be supplied to the authors
to read from. But it is essential that all manuscripts should be
sent exclusively to the Hon. Gen. Secretaries, as above, and not in
any case to other persons. All applications for copies or abstracts
of papers should be referred to the Hon. Gen. Secretaries, and they
will then receive due attention. The following subjects are
suggested for investigation, and the Executive Committee hopes
that members will undertake to work on one or more of the
questions, or upon others that may occur to them.- Hew subjects
have been added to this list to replace those worked out, and the
Committee will be glad to receive questions that may have
presented themselves as desirable for investigation.
PLANT ANALYSIS.
1. Strophanthus. — The chemistry of this drug requires further
elucidation, the statements of various authors hitherto published
being conflicting. (See ‘Year Book of Pharmacy,’ 1888, pp. 60-62;
also 1889, pp. 449-69 ; Pharvi. Journ. [4], iii., p. 463.)
2. Cascara Sagrada. — What is the nature of the various resins
contained in this bark ? (See ‘ Year Book of Pharmacy,’ 1893,
p. 131, from Comptes rendus, cxv., pp. 286-288.)
3. Melon Root. — Torosicviez some years ago isolated from this
root a crude principle possessing marked emetic and purgative
properties. (See Pharm. Journ. [3], xvii., 687.) Required,
an investigation throwing further light on the chemical nature of
this constituent.
4. Spigelia marilandica. — This plant, which is used as an
anthelmintic, is reported by Dr. A. H. Hare to possess poisonous
properties allied to those of gelsemium. (See Practitioner, July,
1887, p. 61.) A systematic examination is required. (See Journ. de
Pharm. et de Chim., 18S8, p. 541.)
5. Cimicifuga racemosa (Actaea racemosa). — Report on
the chemical nature of the constituent or constituents to which
the rhizome of this plant owes its activity. (See ‘ Year Book of
Pharmacy,’ 1885, p. 149.)
6. Euphorbia heterodoxa. — Required, a report on the che¬
mistry of this drug, which, under the name of Alveloz, is recom¬
mended for the treatment of malignant ulcers. (See Pharm.
Journ. [3], xviii., p. 9 ; also American Journal of Pharmacy, July,
1885, p. 328.)
7. Astringent Drugs and Preparations. — The various
methods employed for the estimation of tannin in these give very
discrepant results. Required, a thorough research into the com¬
parative merits of these processes.
8. Mezereon Bark. — What is the chemical nature of the acrid
principle of this bark ?
9. Arnica. — What is the active principle, and what are the
relative proportions of it in the root and flower?
10. Chamomile. — Research on the bitter princip'e contained in
the flowers of Anthemis nobilis. (See Bulletin de la Societd Chemique
de Paris [2], xli., p. 483.)
11. Castor Oil. — A research, having for its object the isolation
of the purgative pi’inciple, either from the oil or the seed.
12. Cascarilla Bark.— A re-examination of this bark is desir¬
able, and particularly with reference to the observation that it
contains an alkaloid closely allied to choline. (See ‘ Year Book of
Pharmacy,’ 1886, p. 168 ; also 1896, p. 301.)
13. Taraxacum. — Little that is definite appears to be known
regarding the active principle of taraxacum root. A research is-
required to clear up the point. (See ‘Proceedings American Pharm.
Assoc.,’ 1896, p. 160.)
14. Colchicum autumnale. — The chemistry of Colchicum-
autumnale is still in an unsatisfactory condition. It has not 3ret
been clearly proved that more than one active principle exists
either in the corm or the seeds. A careful proximate analysis of
both is urgently needed.
15. Distilled Spirit of Witch. Hazel. — In view of the growing
use of this, the separation and examination of the volatile principle-
is desirable.
16. Fucus vesieulosus. — The medicinal virtues have been:
attributed solely to the presence of iodine and bromine. It is not
improbable that it may also contain some organic constituent of
importance. A complete chemical investigation is required.
17- Lobelia inflata. — One alkaloid only has been isolated from
this drug ; the question of the existence of a second is worthy of
attention.
18. Jaborandi Leaves varying from the official description
have been placed upon the market. A comparison of the active
principles with those of the true jaborandi is desirable.
19. Simaruba Bark. — A comparison of the bitter principles-
of this bark with those of quassia wood (both Jamaica and
Surinam).
20. Ipecacuanha. — A further examination of the alkaloids of
ipecacuanha other than emetine and cephaeline.
21. Pilocarpus microphyllus. — Examination of this drug for
alkaloids other than pilocarpine.
22. Damiana is reported to contain a bitter substance, resins,
and volatile oil. The liquid extract of the leaves being now ex¬
tensively used, a thorough systematic examination of this drug is-
desirable.
23. Chelidonium majus. — Required, a proximate analysis of
the fresh juice.
24. Proximate Analyses of the following drugs are also-
needed : — Cactus grcindiflora, Salix nigra, Citmdlus colocynthis, Catlia-
edulis, Ailanthus excelsa, Uemidesmus indicus, and Viburnum pruni-
folium.
CHEMISTRY.
25. Commercial Atropine. — This is stated to be a mixture of
atropine and hy oscyamine. How can they be separated, and what
are the relative proportions ? (Consult Berichte der deutsch. Cliemr
Ges., xxi., p. 1717.)
26. Glycerin.— Required, a good method of estimating this sub¬
stance, applicable, if possible, to pharmaceutical preparations.
27. Strontium Salts. — Some specimens of salts of strontium
met with in commerce contain appreciable quantities of salts of
other bases. A report on the quality of commercial specimens of
salts of strontium is needed.
28. Solubility of Scale Preparations. — It has been noticed
that some scale preparations, notably the potassio-tartrate and
ammonio -citrate of iron, become less soluble with age. To what-
cause is this attributable, and how may it be prevented ?
29. Purity of Pilocarpine. — It is suggested that many speci¬
mens of pilocarpine contain jaborine as an impurity. Is this the
case ?
30. Jaborine. — Does this base exist ready formed in jaborandi,
or is it produced in the process of the manufacture of pilocarpine T
Published evidence points to the latter as the more likely alterna¬
tive.
31. Gun Cotton. — Does the B.P. process yield only the di¬
nitrate of cellulose as stated by some; or (2) a mixture of tetra- and
tri-nitrate, or (3) of tetra- and penta-nitrate, as stated by others ?
(See ‘Year Book of Pharmacy,’ 1896, p. 344.)
32. Albuminate of Iron. — What is the composition of the
so-called albuminate of iron of commerce ?
33. Quinine. — Results obtained in the titration of this alkaloid
suggest the possibility that it is di-basic, and not mono-basic.
(See ‘Year Book of Pharmacy,’ 1894, p. 351.) Further work is
needed to clear up the point.
34. Subnitrate of Bismuth. — It has been noticed that some
samples are much more readily decomposed by alkaline carbonates
than others. What is the cause of this ?
35. Hypophosphites of Calcium and Sodium.— Are the
official tests for the purity of these salts satisfactory ?
488 *
PHARMACEUTICAL JOURNAL.
[June 5, 1837
MATERIA MEDICA AND PHARMACY.
36. The two Sennas of the British Pharmacopoeia are
permitted to he used indifferently.— Do preparations of the
leaves and fruit of the two varieties of senna differ ? If so, to what
extent ?
37. Extraction of Drugs by Pressure. — This mode of ex¬
traction (see Dr. Symes’ suggestions in the ‘ Year Book of Phar¬
macy,’ 1888, p. 356) is likely to produce good results with a
number of drugs. Required, a series of experiments in this direc¬
tion, showing the effect of the process on the quality and yield of
extracts as compared with the corresponding products obtained by
the ordinary modes of extraction.
38. Thyroid Gland. — Several different methods of making
preparations of the gland have been proposed. It is suggested
that these be compared with a view to choosing or devising one
or more that shall be generally acceptable. (See Pharm. Journ.,
[3], xxiii. , p. 321; also Brit. Med. Journ., i., 1893, p. 289;
‘ Year Book of Pharmacy,’ 1894, p. 421.)
39. Standardised Preparations. — Report on commercial
specimens of official standardised preparations, and those needing
standardisation.
40. Effect of Cultivation, Soil, Climate, and Time of
Collection on Medicinal Plants. — Compare the proportions of
active constituents of indigenous plants grown in different districts,
and the effect upon these constituents by time of collection.
41. Musk. — Chemical examination of commercial samples of
natural musk. How far may the odour of natural musk be replaced
by artificial products ?
42. Solvents. — The employment of acetone, benzol, petroleum
ether (benzoline), and bisulphide of carbon in the extraction and
purification of active principles, oils, etc., is to be strongly recom¬
mended. Experiments are required to find out in what cases these
liquids may be employed advantageously. (See Lefort, Journ. de
Pharm., 1869 ; also ‘ Year-Book of Pharmacy,’ 1877, p. 253.)
43. Capsules. — The quality and quantity of medicines in cap¬
sules. (See ‘ Year-Book of Pharmacy,’ 1875, p. 285.)
44. Cotton-Seed Oil.— Can this oil be used advantageously for
any pharmaceutical purposes ?
.45. Mispronunciation of Latin Pharmacopoeia names is
common. — It is suggested that a short prosody be compiled for
purposes of reference.
46. Standardised Tinctures. — Certain Pharmacopoeial tinc¬
tures owe their activity to the presence of one or more resins. Is
it possible to “ standardise” any of these preparations ?
47. Compressed Drugs and Coated Pills. — Required, a
report on the strength and quality of compressed drugs and coated
pills of commerce ?
48. Acetic Acid as a Menstruum. — Acetic acid has been
strongly recommended by F. Hoffman (‘Year Book,’ 1893, p. 190),
and also by Remington {Pharm. Journ., iii. , xxiii., 807), as a
menstruum for the exhaustion of many drugs. An investigation
is required to ascertain for what drugs this is suitable.
49. Kinos. — The official variety is now almost unobtainable.
Can its place be effectively supplied by others met with in
commerce ?
50. Aluminum. — What are the advantages of using this
metal for pharmaceutical apparatus ?
51. Copaiva. — It is suggested that a report on the quality of
the oleo-resin of commerce is desirable.
52. Digitalis.— A comparison of the juice with the official
preparations is desirable.
53. Wool Fat. — A report upon commercial samples of wool fat.
54. Sennas. — A careful histological examination of Alexandrian
and Tinnevelly senna, with the view of ascertaining whether it is
possible to distinguish the two drugs when powdered.
55. Ergot. — The determination of the proportion of alkaloid
extracted from ergot by the official processes for the various pre¬
parations.
56. Syrup of Lemons and Syrup of Poppies. — Good for-
mulse are required for the preparation of the syrups.
57. Extracts. — The official processes for preparing extracts
appear capable of considerable simplification and improvement.
Experiments in this direction are much needed.
58. Cinnamon Bark. — An examination of the commercial
powder is desirable.
59. Strophantlius.— An examination of the seeds and tincture
of strophanthus at present in use in this country, with the view of
determining their variation in strength, and the presence or ab¬
sence of ouabain as an ordinary constituent of the tincture.
PHARMACEUTICAL SOCIETY.
MEETING OF THE COUNCIL.
WEDNESDA Y, JUNE 2, 1897.
Messrs. Allen, Atkins, Bateson, Bottle, Carteighe, Corder,
Cross, Grose, Hampson, Harrison, Hills, Johnston, Martindale,
Newsholme, Savory, Southall, Storrar, Symes, Warren, and Young
were present, and the chair was taken by Mr. Walter Hills.
The minutes of the last monthly meeting and of the special meet¬
ing on May 19 having been read and confirmed,
Mr. Warren addressed the Council. He said he did not
consider himself a new member, as though that was not the first
time he had had the honour of a seat on the Council, it was the
first time he appeared there as an elected member, and he
.should like to heartily thank those who had placed con¬
fidence in him. He believed he should best thank them,
however, by diligently attending to his duties as a London
member. That work might not involve much talk, for in spite of
the taunts levelled at some of them, that they were too weakly
subservient, he believed the work of the Society was better
forwarded by loyal and intelligent co-operation with the chief
whom they elected than by any unnecessary parade of indepen¬
dence. He would say the work of the pharmacists of the country
rather than that of the Society, because, although the two terms
were synonymous to him, it appeared that in some quarters they
did not convey the same idea. He thought any intelligent person
must see that the future of pharmacy must depend on a strong and
respected Pharmaceutical Society. If there were a few privileges
possessed by members over those who were outside, those privi¬
leges were open to all upon the same terms, and whatever good
might accrue, those outside could not help sharing in it, both
morally and materially.
Election oe President.
The ballot having been taken- in the usual way, Mr. Walter
Hills was unanimously re-elected President.
Mr. Hills, in returning thanks for his re-election, said he
was deeply sensible of the great honour that had again been con¬
ferred on him, and he was especially grateful for the unanimity
with which the vote had been given. He had had twelve months’
experience in the office, and he was bound to say that he had
found the duties and responsibilities associated with the office
not inconsiderable, but they had been rendered easier to
him during the past twelve months by the kind consideration
and support of his colleagues. He was sure from the unanimous
vote that had been accorded him that he might rely on that support
for the next twelve months, and with that support he took up the
duties attaching to the office with no hesitation, and felt sure that
together they would be able to do something which would be of
advantage to the Pharmaceutical Society, which they had the
honour to represent.
Election of Vice-President.
The ballot having been again taken, Mr. G. T. W. Newsholme
was elected Vice-President.
Mr. Newsholme thanked the members for the great honour
conferred upon him. He had been a member of the Council for
ten years, and he should like to say how gratifying it was
to him to know that as the result of the recent Benevolent
Fund Dinner there was such an enormous increase in the
additions to the Benevolent Fund over that realised ten
years ago. That was particularly satisfactory to the Vice-
President from the fact that he had to preside over the
Benevolent Fund Committee, which had the administration of that
Fund. It was unnecessary for him to say more, except that he
felt how incompetent he was to fill the position to which he had
been elected, and to follow the distinguished men who had pre¬
ceded him. When he saw around him such men as Mr. Atkins,
Mr. Bottle, Mr. Cross, and others who had preceded him, he
felt that he had very great difficulty in following such men ;
but although they had been brilliant men, he would say that no
man could try to be more loyal to the Society than he. He
had for ten years done his best to further the interests of the
June 5, 1897]
PHARMACEUTICAL JOURNAL.
489
Society, and hoped in the future that he would be able to succeed
as well as some of the men who had preceded him.
Election of Treasurer.
On a further ballot being taken, Mr. Robert Hampson was re -
elected Treasurer for the ensuing year.
Mr. Hampson, in returning thanks for his re-election, said it was
undoubtedly an important position, and he should take care of all
the money placed in his charge, as he had hitherto done. He
hoped that in the future the funds would increase, for there was much
to be done by the Society in the future, for those outside it as
well as for the members.
Standing- Orders.
The Standing Orders of the Council were re-enacted for the
ensuing year.
Reappointment of Officers.
Mr. Richard Bremridgewas reappointed Secretary and Registrar
for the ensuing year ; Dr. B. H. Paul was reappointed Editor, and
Mr. John Humphrey Sub-Editor, of the Journal ; Mr. E. M. Holmes
was reappointed Curator of the Society’s Museum, and Mr. J.
Rutherford Hill was reappointed Assistant Secretary in Scotland.
Examiners for the Council Prizes and Scholarships.
It was decided that Messrs. Balfour, Gibson, and Maben should
be requested to conduct the examination for the Council Prizes
competition in July next. It was also agreed that Messrs. Arkin-
stall, White, and Pinches should be requested to conduct the
examinations for the Jacob Bell Memorial and Manchester
Scholarships.
Death of an Honorary Member.
The President said he had just received information of the
death of a distinguished honorary member of the Society, Dr.
Julius von Sachs, Professor of Botany in the University of Wurz¬
burg. Everyone who took any interest in botany was acquainted
with the work and reputation of Dr. Sachs. He believed he was
one of the pioneers of what might be called the new botany — the
physiology of the living plant, and his works had been translated
into English and were very much read. He was sure it would be
the wish of the Council that he should communicate to his relatives
an expression of sympathy in their bereavement and of regret at
the loss which the world of science had sustained.
Election of Members.
The following, having . passed the Major examination and
tendered their subscriptions for the current year, were elected
“ Members” of the Society : —
Brice, Henry Doyle ; Chelsea. | Dann, Charles ; Tunbridge Wells.
Goodall, Frederic Charles ; Stafford.
Election of Associates in Business.
The following, having passed the Minor examination, being
in business on their own account, and having tendered their sub¬
scriptions for the current year, were elected “Associates in Busi¬
ness ” of the Society : —
Farrants, Francis Samuel ; Orpington.
Fletcher, Charles Senior ; Wakefield.
Goodess, Frederick William ; Leicester.
Green, George T. ; Henley-on-Thames.
Hickin, William Edward ; Birkenhead,
Johnson, Walter; Bournville.
Scott, Thomas L. ; Trimdon Grange.
Wallace, William ; Ardrossan.
Anderson, David ; Penicuik.
Caines, Charles March ; London.
Calder, James ; Bathgate.
Church, Charles Edward ; Andover.
Cuthbert, William Stiven ; Glasgow.
Davies, David ; Pontypridd.
Ellis, William Frederick ; London.
Galloway, Thomas McLaren ; Kirkcaldy.
Griffiths, Horace ; Newport.
Hipperson, Charles W. W. ; Norwich.
Humphreys, Ernest B. ; Manchester.
Jack, Alexander B. ; Dingwall.
Jackson, Charles Henry ; Sunderland.
Wilsden, Arthur
Lamont, John ; Glasgow.
May, Frederick Bertram ; Manchester.
Nicholls, Albert Ambrose ; Hackney.
Norweb, Aithur ; Nottingham.
Onley, Geoffrey Bernard ; Birmingham.
Patterson, J. W. ; Newcastle-on-Tyne.
Plumley, Herbert James ; Bristol.
Rogers, Robert Isaac ; Rhos.
Ross, Edward ; Wiveliscombe.
Smith, George William ; Oakham.
Turner, George Augustus ; Belfast.
Westlake, William Smalley; Sutton.
Wilkinson, Joseph George ; Harrogate.
M. A. ; Wooler.
Restorations to Register.
The names of the following persons, who have severally made the
required declarations, and paid a fine of one guinea, were restored
to the Register of Chemists and Druggists : —
Doe, Walter James ; 19, St. Stephen’s Square, Norwich.
White, Samuel Banfield ; 19, South Street, Wellington, Somerset.
Young, James John ; Midsomer Norton, Somerset.
Andrews, George James ; 136, Stamford Street, E.C.
Several persons were restored to their former status in the
Society upon payment of the current year’s subscription and a
nominal restoration fee of one shilling.
Appointment of Committees.
The Council went into Committee to consider the arrangement
of the different Committees, as the result of which the following
appointments were made : —
General Purposes. — The whole Council to meet on the evening
before the meeting of the Council, and at such other times as may
be necessary.
Finance. — The President (Mr. Hills), Vice-President (Mr. News-
holme), and Messrs. Allen, Carteighe, Grose, Hampson, Martin-
dale, Park, Savory, Storrar, and Warren.
Benevolent Fund. — The President (Mr. Hills), Vice-President
(Mr. Newsholme), and Messrs. Atkins, Bateson, Bottle, Corder,
Cross, Harrison, Johnston, Southall, Symes, and Young.
Library, Museum, School and House. — The President (Mr. Hills),
Vice-President (Mr. Newsholme), andMessrs. Allen, Atkins, Bottle,
Carteighe, Hampson, Harrison, Martindale, Savory, and Warren.
Law and Parliamentary. — The President (Mr. Hills), Vice-
President (Mr. Newsholme), and Messrs. Allen, Atkins, Bottle,
Carteighe, Cross, Hampson, Harrison, Johnston, Martindale,
Park, Savory, Southall, Storrar, Symes, Warren, and Young.
Standing Committee to watch Parliamentary Business, and take
action thereon in the interests of Chemists and Druggists. — The
President (Mr. Hills), Vice-President (Mr. Newsholme), and
Messrs. Allen, Carteighe, Martindale, Savory, and Warren.
Research. — The President (Mr. Hills), Vice-President (Mr.
Newsholme), and the members of the Library, Museum, School and
House Committee.
Evening Meetings. — The Staff of the Society’s School, the Editor,
and the Curator were appointed to assist the President and Vice-
President in making arrangements for the Society’s evening
meetings in London.
Pharmacopoeia.- — The President (Mr. Hills), Vice-President (Mr.
Newsholme), and Messrs. Carteighe, Martin, Inglis Clarke, Cross,
Ekin, Martindale, C. Umney, Harrison, J. Ince, and Professor
Greenish (as Secretary).
Election of Associates.
The following, having passed the Minor examination and
tendered or paid as “Students” their subscriptions for the
current year, were elected “Associates ” of the Society : —
Brodie, John Dallas ; Broxburn.
Brown, John Arthur ; Ripley.
Chapman, Edgar Marsh ; Scarboro’.
Gordon, David ; Liverpool.
Morris, Henry ; St. Clears.
Sharpies, Robert ; Blackburn.
A Congratulatory Address to Her Majesty.
The Vice-President moved —
“ That the President be requested and authorised to draw up and 'send, on
behalf of the Council, a congratulatory address to Her Majesty on the occasion
of her Diamond Jubilee, and that the address be sealed with the corporate
seal of the Society.”
This motion was seconded by Mr. Bottle and carried unani¬
mously.
Election of Students.
The following, having passed the First examination and
tendered their subscriptions for the current year, were elected
“ Students ” of the Society : —
Finance Committee.
The Secretary read the report of this Committee, which was
of the usual character, and recommended sundry accounts for
payment.
490
PHARMACEUTICAL JOURNAL.
[June 5, 1897
The President, in moving the adoption of the report and recom¬
mendations, said there was nothing to which he need call special
attention, and the proposition was at once put and carried.
Benevolent Fund.
The report of this Committee included a recommendation of the
grants to the amount of £22 in the following cases : —
The widow (47) of an Associate, who received a grant last year, and is en¬
deavouring to support herself by letting apartments. (Towyn.)
A registered Chemist and Druggist (84), who had a grant in November last.
(London.)
Two cases were deferred for further information.
Mr. Harrison, as Chairman of the Committee, moved the adop¬
tion of the report. There were only four cases before the Com¬
mittee on the previous day, two of which were deferred for
further information, but in the other two cases grants were
made. They were both cases of such an extremely
painful nature that the Committee had no hesitation
in arriving at a conclusion that relief ought to be given.
Although the demands on the Fund this month were small, there
was no reason to expect that they would remain so for any length
of time, therefore the splendid response to their late appeal was
the more to be appreciated. Their friends all over Great Britain
recognised that an attempt was made to administer the Fund in a
directly practical spirit, and were satisfied that in their hands the
best possible use had been made of the funds placed in their hands
for benevolence.
The report having been agreed to unanimously,
The President said he should like to say a word with reference
to the late Festival Dinner. He might mention that 262 persons
dined at the Hotel Cecil on the 18th ult., and that the sale of
tickets and the contributions from stewards who were not able to
attend had provided sufficient to pay for the dinner and to leave a
balance which would, to a small extent, swell the amount of sub¬
scriptions and donations announced at the dinner. It was very
satisfactory, therefore, to record that the expenses had not
entrenched on the donations. It was proposed that the Special
Fund should be kept open to the end of the month in order to give
opportunities to those who had overlooked the matter, and others
who would wish to add to their subscriptions. He might mention
that the total amount contributed or promised up to the present
was £2175. He hoped that that amount would be further increased
before he announced the completed total at the Council meeting in
July.
Library, Museum, School, and House Committee.
The report of this Committee stated that the Librarian’s report
had been received, and included the following particulars
April
Attendance.
/Day .
' \ Evening .
Circulation of Books.
April .
Total.
. 161
following particulars : —
April
Attendance.
/Day .
• \ Evening . . .
Total.
Highest.
Lowest. Average.
.. 273
19
4
12
11
0
4
Town.
Country.
Carriage paid.
73
88
£1 Os. 2d.
also been received,
and included the
Total.
Highest.
Lowest.
Average.
. 473
32
10
20
. 35
3
1
2
Several donations had been received (Pharm. Journ., May 15, p. 413), and the Com
mittee directed that the usual letters of thanks be sent to the respective donors.
The President moved the adoption of the report, and that was at
once agreed to.
The Inaugural Address.
It was resolved that the selection of a gentleman to deliver the
inaugural address at the commencement of the autumn session
should be referred to the Library, Museum, School, and House
Committee.
Vote of Thanks to the Retiring Vice-President.
At this stage, the President proposed —
“ That the hearty thanks of the Council be awarded to Mr. John Harrison for
his valuable services as Vice-President during the past two years.”
He said no words of his were necessary to recommend this resolution
to the favourable notice of the Council and for their hearty acclama¬
tion. They were all thoroughly acquainted with Mr. Harrison
and with the many qualifications which he possessed for the office
he had just vacated. They were all charmed with his eloquence,
and knew what a good man of business he was. They also knew
how loyal Mr. Harrison was to the best interests of the Society,
therefore he had no hesitation in asking the Council to approve of
the motion.
Mr. Carteighe said he had been asked to second this motion,
as Mr. Harrison was associated with him during one of his years
of office, and he (Mr. Carteighe) could therefore thoroughly
appreciate his value and the manner in which he fulfilled his
duties. There were great advantages in having as Vice-President
a member of Council who did not reside in London ; but on
the other hand, the difficulties under which the duties were
performed by such gentlemen were such as gentlemen in London
could hardly appreciate. The Vice-Pre-ident had to come to
London, to go to Scotland from time to time, to attend the meetings
of the Boards of Examiners, and to be constantly in touch with the
President. In every position in which Mr. Harrison was called on
to fulfil during his association with him, he never saw a more busi¬
ness-like or more admirable Vice-President.
The Vice-President said he must add a word in support of the
proposition, as he felt that Mr. Harrison had performed his duties
with satisfaction to every member of the Society and to the whole
country. He occupied a prominent position in his own town,
having recently been elected an alderman and having been for
many years a Justice of the Peace, so that it was a marvel to him
how he found time to fulfil his duties, but there was no doubt he
did them very well.
The resolution having been passed unanimously,
Mr. Harrison said he was in the unique position of feeling
called upon to respond to a vote of thanks proposed by a President
and seconded by a Past President, both of whom it had been one
of his highest privileges to serve under. With both of the
presidents under whom he had served he had been in the closest
intimacy. The two years during which he had filled the office,
although exceedingly responsible ones and well charged with work,
were very pleasant ones to him, and the experience of those two
years had taught him a very valuable lesson. He could not help
thinking that during the last two years, although they had not
shown the legislative activity which Mr. Southall might desire, still
they had been years of exceeding administrative activity. There
had been many pressing questions brought before them for solu¬
tion, and all of them were now in a fair way to be satisfactorily
settled ; there was the re-organisation of the Research Laboratory
of the School, and the development of the Journal, the work of the
Pharmacopoeia Committee, and lastly, but by no means least, there
were the proposed new bye-laws. That showed clearly that in
addition to all the usual work of the Society which, as every one
who had any experience knew, was rapidly growing in volume, they
had had all these important questions before them, and he believed
they had been settled on a sound and satisfactory basis, and in a
manner conducive to the welfare of the Society.
Vote of Thanks to Mr. Gostling.
The President next moved : —
“ That this Council desires to record its sense of the services rendered by Mr.
T. P. Gostling during the many years he has been a member of the Council,
and for his valuable services as Vice-President of the Society during the
years 1886-1888.”
Mr. Gostling was well known to every member of the present
Council, as he had been associated with them for many years. He
happened to be Vice-President on the occasion of the
Jubilee of Her Majesty’s reign, and signed the address of con¬
gratulation on that occasion. He had always been distinguished by
his great loyalty to the highest interests of the Society, and though
he did not speak much, when he did it was always on the side of
advancement in the widest sense. Their best wishes would go
with him in his retirement, and they hoped that the comparative
rest he would now have, both from business and public duties,
would be beneficial to him, and that he would have many years of
health and happiness before him.
The Vice-President, in seconding the resolution, said he could
not but regret that it was necessary, for he had hoped that Mr.
Gostling would have remained with them some time longer. Still,
as he seemed to think that he required a little more ease, they
could only acquiesce in his decision, and he might echo everything
the President had said. They all looked on him as a friend, and
as a man who was very loyal to the Society.
June 5, 1897J
PHARMACEUTICAL JOURNAL
491
Mr. Atkins said he should like to say one kindly word about
Mr. Gostling, who was an exceedingly genial, lovable, and excellent
man. They all enjoyed his friendship, and he especially, as he
had many times been a visitor at his house. They had never had
a more loyal man on the Council than Mr. Gostling. He could
not say that he retired with his (Mr. Atkins’) approval, as he had
tried to dissuade him from that course, for he thought he had
many years of activity before him. Although Mr. Gostling had
retired from the Council, he had not retired from sympathy with
the Society and its interests, and, as was well known, he had
special advantages in being in touch with the medical profession,
having two successful and distinguished sons.
The motion was unanimously agreed to.
Correspondence.
The President announced that he had received a letter from
Mrs. Attfield, asking him, as the President, to accept a portrait of
Dr. Attfield on behalf of the Society. The picture had not arrived
at the present time, because it was awaiting the signature of Pro¬
fessor Herkomer, the artist, who was now on the Continent, but it
might be expected in a few days, and he was sure the Council
would wish him not only to accept it, but also to thank Mrs. Att¬
field for the presentation.
Several other letters were also read.
General Purposes Committee.
The Council went into committee, as usual, to he3r and consider
the report of this Committee, which included the solicitor’s report
on cases placed in his hands. On resuming, the report and recom¬
mendations were carried unanimously, and special resolutions were
passed authorising the Registrar to take proceedings against certain
persons named therein.
LIST OF DONATIONS & SUBSCRIPTIONS
IN AID OP THE
BENEVOLENT FUND.
The following additional donations and new or increased annual subscriptions
have been received since the publication of the first list. A further list will be
published at the end of this month
Dons. Subs.
Amoore, A. S. ; 173, Sloane Street, S.W. . . 2 2 0
REAGENTS, REACTIONS, METHODS AND FORMULAS,
KNOWN BY THE NAMES OF THEIR AUTHORS.
A list of reagents and reactions known by the names of their
authors was published by A. Schneider in the Pharmaceutische
Centralhcdle some years ago, and this has since been revised and
enlarged by Dr. Julius Altschul, a translation of whose list by R.
Fischer has been published in the Pharmaceutical Review, and
since reprinted in pamphlet form. Referring to this list, Dr. Alts¬
chul says : “As far as the selection of material is concerned, stress
has been laid principally on qualitative reactions. Quantitative
tests have been added only in so far as they serve also for qualita¬
tive determination. Most of the items belong to the technical,,
pharmaceutical, and physiological branches of chemistry. Of bac¬
teriological reagents only a few of the most important were added.”
With the idea of increasing its utility, the list is now further-
amplified by the addition of particulars regarding a large number
of microscopical and bacteriological methods and formulae, collated
from the works of Lee, Squire, Crookshank, and others. It is
possible that other useful additions may suggest themselves to
readers, and they are requested to notify any omissions in order
that the list may be rendered as complete as possible.
Adamkiewics’ stain for nerve-centres. Sections of material
hardened in Muller’s solution for 1 to 3 months are stained with
concentrated solution of safranine, after being washed first in
water, and then in water acidified with nitric acid. Afterwards
remove superfluous colour and clear by treatment with alcohol and
clove oil, pass into water once more, then wash in water acidified
with acetic acid, stain with methylene blue, and clear as before.
Myelin is stained red, and nuclei violet.
Adamkiewics’ reaction for albumin. Acetic acid solutions of
albuminous substances are coloured violet and show a greenish
fluorescence upon the addition of concentrated sulphuric acid.
The result is the same if the albumin is treated with a mixture
of 1 vol. of concentrated sulphuric acid and 2 vol. of glacial acetic
acid, the reaction being facilitated by the application of heat, and
also, according to Wurster, by the addition of a few grains of
sodium chloride.
Agostini’s reaction for glycose. On adding to 5 drops of urine
5 drops of 0-5 per cent, gold chloride solution and 3 drops of
20 per cent, potash solution, and gently heating the mixture, the
presence of sugar will be indicated by the formation of a red
Andrews, F. ; 34, Leinster Terrace, W . 1 1 0
Bagshaw, H. B. ; Oldham . 1 1 0
Bagshaw, W. ; Oldham . Ill 6
Bullock, J. Lloyd ; 3, Hanover Street, W . 5 5 0
Butcher, W. and Son ; Blackheath, S.E . 1 1 0
Cooper, W. and Nephews ; Berkhamsted . 21 0 0
Davidson, P. ; 342, High Road, Brondesbury, N.W . 2 2 0
Gerrard, A. W. ; Guildford Street, Chertsey . 1 1 0
Glasgow Apothecaries’ Company . 10 10 0
Harker, C. R., Stagg, and Morgan ; 15, Laurence Pountney
Lane, E.C . 5 5 0
Hewlett, C. J. and Son ; Charlotte Street, E.C . 5 5 0
Homer and Sons ; Mitre Square, E . - . 10 10 0
Huskisson,H. O. ; Swinton Street, Gray’s Inn Road, W.C. 2 2 0
Johnston, J. ; 45, Union Street, Aberdeen . 2 2 0
Leins, H. ; 149, Houndsditch, E.C . 1 1 0
Manchester and District Chemists’ Assistants, and
Apprentices, per John Riding . 20 0 0
Matthews, C. W. ; 6, Fortess Road, N.W . - . 1 1 0
Nottingham and Notts Chemists' Association . 10 10 0
Nurthen, F. W. ; 390, Strand, W.C . 1 I 0
Park, C. J. ; 1, Mutley Plain, Plymouth . 2 2 0
Parker, R. H. ; 35, Clifton Road, Maida Vale, W . 1 1 0
Rankin and Borland ; 7, King Street, Kilmarnock . 5 5 0
Silverlock, H. ; 92, Blackfriars Road, S.E . 5 5 0
Tanner, A. E. ; Tottenham . 2 2 0
Thompson, John; 58, Hanover Street, Liverpool . . 110
Wigginton, A. ; 137, Sloane Street, S.W . 2 2 0 1 1 0
Willows, Francis and Butler ; 101, High Holborn, W.C. 5 5 0
Wodderspoon and Co. ; 7, Serle Street, W.C . . . 2 2 0
Other contributions of smaller sums amounting to . 7 11 0
colour.
Alleger’s gelatin process. Add a few drops of formalin to each
gramme of 0'5 to 1 per cent, gelatin solution. After mounting the
section in this, apply heat to the slide until the paraffin is
softened, and allow the superfluous gelatin to drain from the edge
of the slide.
Allen’s reaction for vegetable fats. Shake together equal
volumes of fat and nitric acid, sp. gr. 1 ‘4, for half a minute and
then set aside for 15 minutes. The presence of vegetable fats is
indicated by the formation of a coffee-brown colour.
Allen’s reaction for phenol. A carmine-red colour is produced
with hydrochloric and nitric acids.
Allen’s stain for embryos. Dissolve O'l per cent, methylene
blue in salt solution (0'75 per cent, sodium chloride in water), and
dilute with 15 to 20 volumes of sea water.
Almen’s reagent for blood. Well shake the liquid containing
blood with a mixture of equal parts of tincture of guaiaeum and
turpentine oil, when it will become blue owing to the precipita¬
tion of guaiaeum resin. The colour is permanent when heated.
See also Weber and Schoenbein.
Almen’s tannin solution acts as a precipitant of albumin. It
is a solution of 4 Gm. tannin, and 8 C.c. of 25 per cent, acetic acid
in 190 C.c. of 40 to 50 per cent, alcohol. It also precipitates
nucleo-albumin.
Almen’s reagent for glucose. Digest 2 Gm. of basic carbonate
of bismuth with 100 C.c. potash solution, sp. gr. 1'33, and 4 Gm.
Rochelle salt. Upon cooling, the clear solution is decanted
from the precipitate. On boiling 1 C.c. of the reagent for several
minutes with 10 C.c. of urine, if glucose is present a yellowish-
brown precipitate is formed, which becomes darker and finally
black. This reagent is also known as the Boettger-Almen reagent.
Compare also Nylander’s solution.
492 PKARMACEUTICAL JOURNAL. [June 5, 1897
Alt’s nerve stain. Solution of Congo red in absolute alcohol.
Squire recommends a 2 per cent, solution in water.
Altmann’s ammonium molybdate. A 2 5 per cent, solution to
which is added about 0 '25 per cent, of chromic acid.
Altmann’s nitric acid. A 3 to 3 '5 per cent, aqueous solution
used as a fixing agent. Specific gravity about 1 ’02.
Anderson’s reaction for distinguishing between chinoline and
pyridine salts. This is based on the fact that the chloro-platinates of
pyridine salts, when boiled with water, are converted into insoluble
■double salts, with the elimination of hydrogen chloride, whereas
chinoline salts remain in solution.
Apathy’s hsematoxylin stain. After staining in 1 per cent,
solution of hsematoxylin in 70 or 80 per cent, alcohol, wash out in
1 per cent, solution of potassium bichromate in alcohol of the same
strength. The bichromate solution should be freshly made by
mixing one part of a 5 per cent, aqueous solution with about 4 parts
of 80 to 90 per cent, alcohol.
Apathy’s methylene blue process. Preparations stained with
strong methylene blue solution are washed in salt solution (0'75 per
cent.), then placed for an hour or more in freshly-prepared 1 to 2
per cent, solution of neutral ammonium carbonate, saturated with
picrate. If the methylene blue solution is very dilute omit the
treatment with salt solution. Afterwards immerse preparations
in a saturated solution of ammonium picrate in 50 per cent,
glycerin, then remove into a saturated solution of the picrate in a
mixture of 2 parts of glycerin (50 per cent.), 1 part of cold
saturated sugar solution, and 1 part of cold saturated gum arabic
solution. When thoroughly penetrated, mount in Apathy’s
mounting medium.
Apathy’s mounting medium. Picked gum arabic, 50 Gm. ;
cane sugar, 50 Gm. ; distilled water, 50 Gm. Dissolve over a
water bath and add 0-05 Gm. of thymol. This medium sets very
hard and, combined with a paper cell, it may be used for ringing
glycerin mounts.
Arata’s test for artificial dye-stuffs in wine. Wool immersed
in wine containing artificial dye-stuffs abstracts them from the wine.
The fibre is afterwards subjected to special reactions.
Arndt’s determination of sugar by means of the ferment
saccharometer. See Einhorn.
Arnold’s reactions for alkaloids. — I. — Certain alkaloids when
heated on the water bath with syrupy phosphoric acid, obtained
by dissolving metaphosphoric acid or phosphoric anhydride
in phosphoric acid Ph. G. III., produce characteristic colour
reactions : aconitine — violet ; nicotine — yellow ; coniine — green.
II. — Others, when triturated with concentrated sulphuric acid,
yield characteristic colour reactions upon the addition of concen¬
trated solution of potash in 30 to 40 per cent, alcohol (or in some
instances water). III. — Arnold-Vitali’s reaction. A small quantity
of alkaloid is triturated with concentrated sulphuric acid and a grain
of sodium nitrite added; then, as in II. , strong potash solution.
A number of alkaloids produce characteristic colour reactions.
Thus atropine and homatropine produce with sulphuric acid
and sodium nitrate an orange-yellow colour which upon the
addition of potash becomes reddish-violet and afterwards fades to
rose-red.
Arnold’s reaction for narceine. When a substance containing
narceine is heated with concentrated sulphuric acid and a trace of
phenol, a reddish colour is produced.
Axenfeld’s reagent for albumin is a 01 per cent, solution of
gold chloride. The solution to be tested is acidulated with formic
acid and heated with a drop of the reagent. If albumin be present,
the solution becomes purplish, and upon the addition of more gold
chloride the colour changes to blue. The latter colour reaction is
also produced by glucose, starch, tyrosine, leucine, etc., but the
purplish colour is characteristic of albumin.
Aymonier’s reaction for a-naphthol. Upon adding cane sugar
to a 15 per cent, alcoholic solution of a-naphthol and mixing with
2 vols. sulphuric acid, it is coloured violet. The addition of one
drop of a mixture of 1 part potassium bichromate, 10 parts water,
and 1 part concentrated nitric acid to an a-naphthol solution yields
a black precipitate. /3-naphthol does not produce either of these
reactions.
Azoulay’s osmic acid method. Thin sections of material
hardened in Muller’s solution are placed for 5 to 15 minutes in osmic
acid solution (1:500 or 1:1000), then rinsed with water and left for
2 to 5 minutes in a 5 or 10 per cent, solution of tannin, the latter
being warmed meanwhile until vapour is given off. After washing in
water, double-stain the sections with carmine or eosine, and mount
in balsam.
Bach’s reagent for hydrogen peroxide consists of the following : —
(a) 0-03 Gm. of potassium bichromate and 5 drops of aniline in 1 litre
of water ; (b) 5 per cent, oxalic acid solution. On shaking 5 O.c. of
the solution to be tested with 5 C.c. of solution (cs) and 1 drop
of solution (b), a violet-red coloration is produced when hydrogen
peroxide is present.
Balmer-Friintzel method of staining tubercle bacilli. Immerse
sections for 24 hours in solution of 2 Gm. of freshly-powdered
gentian violet in 100 Gm. of aniline water. Subsequently treat as
in Erlich’s method.
Barbot’s reagent for fatty oils is fuming nitric acid. Different
oils vary in their behaviour as regards coloration and solidification
when mixed with this reagent. Olive oil yields a white (not red
or brown) mixture which solidifies after 1 to 2 hours.
Barfoed’s reagent for glucose. A solution of 14 Gm. crystallised
copper acetate in 200 C.c. water and 5 C.c. acetic acid, or it may
consist of 0 ‘5 copper acetate in 100 C.c. water and 1 C.c. acetic acid.
Glucose reduces this solution in the cold, and more quickly upon
heating. Dextrin, cane sugar, and milk sugar do not reduce the
solution. It is used for distinguishing between glucose and
lactose in urine.
Barreswil’s reagent for glucose. The same as Fehling’s solution,
except that it contains potash in place of soda.
Basoletto’s reagent. A mixture of equal parts by volume of
sesame oil and a 2 per cent, solution of cane sugar in hydrochloric
acid, sp. gr. 1T24, is coloured red in the cold, but more rapidly
upon heating. W ith glucose and lactose the colour is produced
only when the mixture is boiled with the hydrochloric acid and
allowed to cool. Compare Baudouin’s test.
Bastian’s gold stain. Solution of gold chloride (1:2000), acidu¬
lated with hydrochloric acid (1 drop to 75 C.c.).
Bates’ safranine solution. A saturated solution in aniline water
(aniline, 3 C.c. ; distilled water, 90 C.c.), prepared at 60° C. and
afterwards filtered.
Bates’ method of examining bacterial cultivations. Remove a
little of the growth by means of a sterilised platinum hook or
small loop, and spread it out on a cover-glass in as thin a film as
possible. When almost dry allow one or two drops of weak
aqueous methyl violet solution to fall upon the film from a
pipette. Carefully turn the cover-glass over on to a slide after
a minute, and then gradually remove the excess of stain by gentle
pressure with a strip of filter paper.
Bates’ method of staining leprosy bacilli. Stain with a solution
of rosaniline hydrochlorate in aniline water, decolorise in 33 per
cent, hydrochloric acid, and after-stain with methylene blue.
Bates’ method of staining the comma bacilli of Koch. Leave
sections for 24 hours in an aqueous solution of fuchsine, then wash
in distilled water faintly acidulated with acetic acid, or in subli¬
mate solution (1:1000). Afterwards, pass rapidly through alcohol
and clove oil, dry with filter paper, and preserve in balsam.'
Baudouin’s test for sesame oil. The reagent consists of OT Gm.
sugar dissolved in 10 C.c. hydrochloric acid, sp. gr. 1T8. One
volume of this solution is shaken with two volumes of the oil to be
tested. If sesame oil be present, the oil upon separation is cherry-
red. According to Lewin, the reaction is carried out as follows :—
0-5 Gm. of finely pulverised sugar in a test-tube is covered with
2 C.c. of the oil, then 1 C.c. of hydrochloric acid, sp. gr. IT 8, is
carefully poured down the sides of the tube. If sesame oil is
present, a rose-red zone is formed within 1 to 5 minutes.
According to Millian, Baudouin’s test is more delicate when carried
out with the well-dried free fatty acids which have been obtaine I
from the oil. Villavecchia and Fabris, replace the sugar and
hydrochloric acid by furfurol. Compare also Carlinfanti and
Gassend.
Baumann’s reagent for polyatomic alcohols and diamines.
Benzoyl chloride is added to the solution of the alcohol or amine in
aqueous soda solution. Insoluble benzoyl esters are precipitated.
This reagent is used for the detection of glycerin, carbohydrates,
and various products of bacterial activity in urine.
Baumgarten’s bleu de Lyon stain. Sections of material
previously stained with borax carmine are placed for 12 hours in
a 0-2 per cent, solution of bleu de Lyon in absolute alcohol,
and washed out for 6 hours before mounting in balsam.
Baumgarten’s fuchsine and methylene blue stain. Sections of
material hardened in chromic acid solution are placed for twenty-
four hours in a watch -glassful of water to which 8 to 10 drops of
concentrated alcoholic solution of fuchsine have been added. Rinse
with alcohol, stain for 4 or 5 minutes in concentrated aqueous
solution of methylene blue, wash out with alcohol for 5 to 10
June 5, 1897]
PHARMACEUTICAL JOURNAL.
493
minutes, and clear with clove oil. Nuclei are stained red and
tissues blue.
Baumgarten’s method of examining tubercle bacilli. Cover-
glass preparations are immersed in a watch-glass of distilled water
to which 1 or 2 drops of potash solution (33 per cent. ) have been
added, and then pressed down on slides and examined unstained.
If putrefactive bacteria are present they may be stained with
aqueous solution of fuchsine or gentian violet, and thus distin¬
guished from the tubercle bacilli, which remain colourless.
Baumgarten’s new method for tubercle bacilli. Stain sections
in a solution prepared by adding 4 or 5 drops of concentrated
alcoholic methyl violet solution to a watch-glassful of water. Wash
in water, and decolorise in absolute alcohol for 5 or 10 minutes,
previously immersing for 5 minutes in a half-saturated solution
of potassium carbonate, if necessary. After passing through
clove oil, mount in a mixture of equal parts of Canada balsam,
free from chloroform, and clove oil. Subsequently, place the
sections in alcohol for 5 minutes, and then in a concentrated solu¬
tion of Bismarck brown in 1 per cent, acetic acid.
Bayer’s reaction for indol. A solution of indol yields a red
colour or precipitate upon the addition of dilute nitric acid and
dilute potassium nitrite solution.
Bayerl’s decalcifying fluid. Equal parts of 3 per cent, chromic
acid solution and 1 per cent, hydrochloric acid.
Beale’s ammonia carmine. Carmine, 10 grs. ; strong solution
of ammonia, 30 mins. ; distilled water, 2 ozs. ; alcohol, 0'5 oz. ;
glycerin, 2 ozs. Dissolve the carmine in the ammonia by the aid
of heat, boil for a few seconds, and let the solution cool. Then
allow the excess of ammonia to evaporate, add the other ingredients,
and filter. If any carmine should deposit on keeping, add one or
two drops of ammonia solution to redissolve it.
Beale’s cement. A thick solution of shellac in alcohol. The
addition of 20 drops of castor oil to each ounce has been
recommended.
Beale’s creosote mixture for imbedding microscopic prepara¬
tions. To a solution of 180 Gm. methyl alcohol and 11 Gm.
creosote, add sufficient chalk to make a thick paste. While con¬
stantly stirring, add 1920 Gm. of water, and then a few fragments
of camphor. After standing for several weeks the mixture is filtered.
Beale’s digestion fluid. The dried mucus from the stomach
glands of the pig (or prepared pepsin) is dissolved in water or
glycerin, and tissues are kept in the solution for some hours at a
temperature of 37° C.
Beale’s glycerin jelly. Gelatin or isinglass is soaked for 2 or 3
hours in cold water, then removed and melted. On cooling, but
whilst still fluid, add a little white of egg, shake well, and heat to
boiling point. Filter through fine flannel to remove coagulated albu¬
min, and to the clear solution add an equal bulk of strong glycerin.
Bechi’s test for cottonseed oil. Upon heating with an alcoholic-
ethereal silver nitrate solution, cottonseed oil yields a reddish-brown
colour ; olive oil and other oils remain uncoloured. The Swiss Society
for Analytical Chemists in 1895 suggested the following mode of
applying the test : — To 1 Gm. silver nitrate, dissolved in 5 C. c. of
water, 200 C.c. alcohol, 20 C.c. ether, and 1 C.c. nitric acid, sp. gr.
1*4, are added. In order to test for cottonseed oil, 10 C.c. of the
fat and 3 C.c. of the reagent are mixed, and the mixture is heated
on a boiling water bath for ten minutes. If cotton-seed oil is
present, the mixture becomes brown, or even black. Compare
Millian’s reaction.
Becker’s reaction for picrotoxine. The alkaloid reduces
Fehling’s solution when gentle heat is applied.
Bedot’s fixing process for delicate pelagic animals. Add sud¬
denly a large quantity of 15 to 20 per cent, cupric sulphate
solution to the sea water containing the animals, and as soon as
the latter are fixed add a few drops of nitric acid and leave for 4 or
5 hours. Harden by adding two volumes of Flemming’s ‘ ‘ strong ”
solution to each volume of sulphate solution, leave for 24 hours,
then add a few drops of 25 per cent, alcohol, and during the next
15 days add more alcohol gradually until the strength of 70 per
cent, is attained. Use 90 per cent, alcohol for definite preservation.
Behren’s test for fatty oils. When treated with a mixture of
equal parts of sulphuric acid, sp. gr. 1 '835 to 184, and nitric acid,
sp. gr. 1'3, different oils show different behaviour. Sesame oil
produces a green colour.
Beissenkirtz’ reaction for aniline. If a grain of potassium
bichromate is added to a solution of aniline in concentrated sul¬
phuric acid, the solution first becomes red, and then blue, the
colour gradually disappearing.
( To be continued. )
NOTES AND FORMULA.
( Specially abstracted for the Pharmaceutical J ournal. )
Perfumed Satchets.
Pieces of fine kid of suitable shape are soaked in a closed vessel
for three days in the following solution
Oil of Bergamot . . „ . 25
Neroli Oil . 20
Bitter Almond Oil . 1
Oil of Orris . 40
Tolu Balsam . 30
Cumarin . 2
Rectified Spirit . 100
The pieces of leather should then be dried on a line in a room of
the temperature of 17 '5° to 20° 0. After some days the rough side
of the pieces of leather should be painted with gum arabic, and
finely-pulverised orris root strewn on and again dried. Then
prepare a mixture of 2 grms. finely-pulverised musk and 2 grms.
civet, and mix to a paste with a little gum arabic. Smear on both
sides of the leather and dry again. Two pieces of leather are then
stuck together, wound round with wadding, and covered with silk
or other fancy material. These satchets will be found to be of
lasting perfume and are much liked, as they do not give off any
dust or powder. — Deutsch. Amer. Apoth. Zeitcj., xvii., 157.
Copper in Oysters.
Lowe states that some time ago a sample of oysters was brought
to him by a friend, which upon examination he found to contain
copper. In some this was apparent to the eye, though in others,
which also contained a considerable quantity of copper, this was
not visible. [Oysters are often tinted green by the spores of algae:
such coloration is no indication of the presence of copper. Ed. ,
P. J.~\ The shells contained no copper, and were free from
colour. The copper contained in a single oyster amounted to 40
milligrammes, so but few of them were required to produce very
unpleasant results. — Analyst, xxii., 86.
Manufacture of Sulphur Soap.
(a) 1 part of sulphurated soda is dissolved in water, the
solution filtered and mixed with 2 parts of curd soap. The
soap thus formed is evaporated to dryness on the water bath.
(b) 25 parts coco-nut oil, 5 parts lard, and 2 parts of lanoline
are saponified with 16 parts potash solution of 38°. The partly
cooled mass is then at once well mixed with 2\ parts of
sulphur and 2| parts of water, and perfumed with J part
of lemon oil and part of cassia oil. (c) 25 parts coco-nut oil and
8 parts of lard are saponified with 16 parts potash solution 38°.
The partly cooled mass is at once well mixed with 2 parts of
flowers of sulphur and 6 parts of water coloured with saffron yellow
dye (dissolved in hot water), and perfumed with essence of lemon.
— Pharm. Zeit., xlii., 262.
Silvering Tinware.
According to Stockmeyer’s process a solution of 3 grammes of
subnitrate of bismuth is prepared in 10 C.c. of nitric acid of 1 "4
specific gravity, to which is added a solution of 10 grammes of
cream of tartar and 40 grammes of muriatic acid in 1 litre of water.
The tinware, freed from fat and oxide, is immersed in this
solution. The metallic bismuth depositing on the surface is
rubbed off, after which the articles appear dark steel-grey. A
mixture of 10 grammes chloride of silver, 30 grammes of salt, 20
grammes cream of tartar, and 100 grammes powdered chalk, is
then rubbed with a slightly moist flannel on the bismuth
surfaces of the articles. The silver will only bite on very thinly,
and it must be protected by a protective coating of celluloid or
other varnish. — Pharm. Centralh., xxxviii. , 279.
494
PHARMACEUTICAL JOURNAL.
[June 5, 1897
PARLIAMENTARY NOTES AND NEWS.
Whether the Merchandise Marks Act, 1887, is to be
regarded as a Heaven-sent blessing or a trade-destroying
curse, is a problem that still engages the close attention of the
Merchandise Marks Committee. At the meeting, on the
24th ult., the evidence of witnesses representing provincial
chambers of commerce was taken — notably Manchester and
Sheffield. The former was represented by Mr. C. Bailey,
of the Manchester Chamber of Commerce, who praised
the present Act with no uncertain voice. It had, said he,
raised the reputation of British goods at home and abroad, and
had done much to stop fraudulent practices. The only thing he
thought necessary to convert the Act into a perfect piece of com¬
mercial legislation was the omission of Clause 16. Now, Clause
16 is the portion of the Act relating to the marking of goods
with the indication of their origin, and Mr. Bailey thought that
sort of thing savoured too much of the Inquisition. With praise¬
worthy candour he told the Committee why Manchester objects to
Clause 16 — Manchester merchants do not want to disclose the
source from which their products are derived.
Mr. H. Hughes, who is Secretary to the Sheffield Chamber of
Commerce and has a legal mind, also expressed himself definitely
in favour of the 1887 Act. It had, he thought, been of great value
in preventing fraud, and though the actual prosecutions under the
Act had been small, the moral effect thereof had been enormous.
According to this witness, there is really no necessity for repealing the
Act, and very little need for amending it. There might be difficulty
in substituting “made abroad ” for the present indication of origin
because Great Britain is a party to the Industrial Property Con¬
vention, and is thereby obliged to guarantee to other countries the
same protection she enjoys herself. Mr. Hughes also pointed to
H.M. Customs as the exciting cause of most of the hostility to the
Act, and urged that a little wiser administration of the law might
remove the grievances arising from unnecessary interference
with trade.
Mr. Carlile (N. Bucks) is going in for a Vaccination Act
of his own. He is tired of the Government’s vacillation on the
subject, and has therefore decided to bring in a Bill to
amend the Vaccination Laws by providing for a compulsory supply
of calf lymph under Government control. We predict that that
Bill will be blocked as soon as it appears. It will be remembered
that the President of the Local Government Board has already
considered the subject of lymph supply, and has expressed his
sympathy with those who, like Sir W. Priestley, want to see an
ideal system established ; but he has also intimated that the cost
Of rearranging and remodelling the present system “gives him
• pause,” and he is not likely to look favourably on a private
member’s Bill which binds the Government to do certain things it
Is not just at present prepared to do.
The President of the Board of Trade is, in the opinion of
Sir Stafford Northcote (Exeter) not occupying his proper posi¬
tion. The department has had during the past few years
a greatly increased amount of work thrust upon it as the
result of the paternal legislation which is occasionally in high
parliamentary fashion. True, most other departments are
suffering from the same complaint, but Sir Stafford singles out
the Board of Trade for a point of new departure, and suggests
that Her Majesty’s Ministry should seriously consider the
advisability of assimilating the position of the head of the
department with that of one of Her Majesty’s principal Secretaries
- of State. The reply to that suggestion will be given as we go to
jpress.
The Metric System Permissive Bill is a fair title for Mr.
Ritchie’s infant, which duly made its appearance on the 27th ult.,
and was to have been read a second time on Monday last, but
failed to get a hearing. It will perhaps have a further chance on
the 3rd inst.
Food and Drugs. — The Kearley Bill is doomed, for it has been
shelved (there is no other name for it) until June 24 — a date so
near the day of jubilation that the probability of the House sitting
is extremely remote. After the Commemoration adjournment,
too, Mr. Balfour has intimated his intention to take as far as
possible non-controversial measures, and a second statement of the
First Lord of the Treasury also stands in the way of the Analysts’
Bill, viz. , the promise to introduce a Government measure which
would deal with the same subject, only in a slightly different manner.
The promise was made to Mr. Dillon (who, being a representative
of an Irish borough, managed to extract a more favourable answer
than Mr. Jeffreys was able to do some few days back), and in the course
of his remarks the Leader of the House conveyed the idea that the
progress of the Government Bill would depend upon the enthusiasm
exhibited therein. Perhaps the Council of the Pharmaceutical
Society may be able to show the Government that among chemists,
at any rate, there is a good deal of very keen interest in the sub¬
ject, and a very heavy sense of dissatisfaction at the present state
of the law and the manner of its administration !
In Committee on the Civil Service Estimates on Friday last
some discussion ensued respecting the brutality of the Patent
Office. Mr. Weir (who is great in Committee) thought it nothing
short of a scandal that this branch of a Government Department
should be a profit-earning one at the expense of the poor inventor.
To mark his sense of this enormity he moved to reduce the vote
by £1000. His principal grievance seems to us to have some
foundation. He complains that there is no examining body to
prevent the unwary soi-disant inventor from paying his fees in
respect of a worthless, notion devoid of novelty. The result is that
perhaps fifty patents are sometimes granted for the same thing,
the Patent Office taking fifty fees and practically saying to the
patentees, “Fight it out amongst yourselves as to
who has the real right of exclusive user.” Mr. Burns
supported his friend from Ross and Cromarty. Air.
Ritchie, in reply, dwelt upon the great reduction of fees
whereby it was made possible for a person to secure protection for
nine months for his notion for £1, and a further protection at the
rate of £1 for every year. But he naturally did not remark that
this “ protection at store prices ” is a delusion and a snare, and that
those who pay the fees on stale or anticipated notions find later on
that the ‘ ‘ protection ” is not real, and that the right gran ted by Royal
Letters Patent is of no more real value than the degree granted by
an imaginary College of Medicine or Arts. Of course one cannot
expect a branch of a Government Department to take up the work
of practical philanthrophy, but seeing that the Patent Office
exists to foster the inventive faculty of the nation, and stimulate
industrial progress, it is open to the charge almost of dishonesty
in taking money from those who, either from ignorance or from
guile, seek to patent articles which cannot by any stretch of
human ingenuity be termed inventions. It goes without saying
that Mr. Weir’s little reduction of £1000 did not come off, and the
Patent Office is thus left to earn another year’s profit for the
Imperial Exchequer.
Education Department. — Captain Norton has, as we expected
he would, returned to the charge against this Department for not
throwing open to competition the position of Junior Examiner. He
brought his heavy artillery to bear on the Treasury this time, in
the shape of a very lengthy question levelled at the head of
Mr. Hanbury, the Secretary to the Treasury. To summarise
the question, the gallant Captain desired to know (a)
whether the method of recruiting (the captain is nothing
if not military) the class of Junior Examiners by open
competition had ever been considered by the Treasury ;
( b ) whether vacancies in the examinership had ever been filled by
means of the Higher Division Civil Service Examination, and if
not why not ? (c) whether the Higher Division Examination was
the method of recruiting the upper staff of the Colonial
Office and the Treasury, and ( d ) whether the Treasury
officials are satisfied that the duties of examiner are so vastly
superior to those of the upper ten in the aforesaid departments
that they cannot properly be performed by those who have
successfully stood the Higher Division Examination test. The
official representative of the Treasury stood the onslaught
remarkably well, and did not seem to be in the least moved to
capitulate. He said the method of open competition had been
considered inapplicable to the Junior Examinerclassof the Education
Department, and the Treasury could not force upon other depart¬
ments the methods by which it filled up vacancies in the ranks of
its own Higher Division. He declined to make comparisons be¬
tween the duties performed by the respective officials of the
Colonial Office, the Treasury, and the Education Department.
June 5, 1837J
PHARMACEUTICAL JOURNAL.
495
Pharmaceutical Journal.
A Weekly Record of Pharmacy and Allied Sciences.
ESTABLISHED 1841.
Circulating In the United Kingdom, France, Germany,
Austria, Italy, Russia, Switzerland, Canada, the
United States, South America, India,
Australasia, South Africa, etc.
Editorial Office: 17, BLOOMSBURY SQUARE, W.C.
Publishing and Advertising Office : 5, SERLE STREET, W.C.
LONDON : SATURDAY, JUNE 5, 1897.
THE COUNCIL MEETING.
As is usually the case at the first meeting of a reconsti¬
tuted Council, the proceedings last Wednesday related chiefly
to the re-election and appointment of officers and Committees
for the ensuing year. After the minutes of the last monthly
•meeting and the special meeting in May had been confirmed,
Mr. Warren took occasion to return thanks for the support
he received at the election and to announce his intention of
•giving diligent attention to his duties as a London member
of the Council.
In the election of President the votes were unanimously
in favour of Mr. Walter Hills, who, in expressing his
sense of the honour conferred by re-election to the office,
hook the unanimous vote as an assurance that he would still
have the same assistance from his colleagues which he had
•already received.
Mr. Newsholme was elected Yice-President by a large
majority of votes, one vote each being given for Messrs.
Allen, Grose, and Southall. Mr. Hampson was re-elected
Treasurer, two votes being given for Messrs. Allen and
Harrison.
Mr. Richard Bremridge was re-appointed Secretary and
Registrar with Mr. Rutherford Hill as Assistant Secretary
in Scotland.
Messrs. Balfour, Gibson, and Maben were requested to
conduct the Examination for the Council prizes in July,
and Messrs. Arkinstall, White, and Pinches, the
examinations for the Jacob Bell and Manchester Scholarships.
The death of Dr. Julius v. Sachs was reported by the
President as having created a vacancy in the list of the
Society’s honorary members, and removed from the world of
.science one of its most distinguished ornaments.
The additions to the Society comprised three members,
fourteen associates, and twenty-seven students.
After the appointment of the various Committees a reso¬
lution was passed, on the motion of the Yice-President,
seconded by Mr. Bottle, that a congratulatory address,
sealed with the Corporate Seal of the Society, should be
sent to Her Majesty on the occasion of the Diamond Jubilee.
The reports of the Finance and Benevolent Fund Com¬
mittees were of the usual character, and were adopted without
•discussion. Two grants amounting together to £22 were
ordered to he paid, and Mr. Harrison, the Chairman of the
Committee, spoke of the splendid response made to the late
appeal on behalf of the Benevolent Fund as an evidence that
the efforts of the Council to administer the Fund in the best
possible way were recognised throughout the country.
The President also drew attention to the very successful
results of the dinner, and added that in order to give ample
opportunity to any who might have overlooked the matter,
the subscription list will be kept open until the end of the
month.
Before the conclusion of the meeting a resolution was
passed, on the motion of the President, seconded by Mr.
Carteighe, thanking Mr. John Harrison for his valuable
services as Yice-President during the past two years. A
similar resolution was passed expressing the Council’s sense
of the services rendered by Mr. Gostling during many years
as a member of Council and as Yice-President.
The President mentioned that he had been requested by
Mrs. Att field to accept, on behalf of the Society, a portrait
of Dr. Attfield, which had been executed by Professor
Herkomer. The substance of various letters from provincial
associations was then communicated, and the proceedings
were closed with the adoption of the report and recom¬
mendations of the General Purposes Committee as to certain
cases in which the Registrar was authorised to take pro¬
ceedings.
PROFESSIONAL AND COMMERCIAL INTERESTS.
It would appear from the tone of Mr. Glyn- Jones’ letter
that he assumes the existence of some inconsistency between
opinions expressed in the Pharmaceutical Journal last week
and statements published on former occasions. But the incon¬
sistency is apparent only, misconception having arisen on
his part through interpreting attempts to take an impartial
view of present-day tendencies in business as expressions of
opinion on specific questions not necessarily involved. No
greater mistake can be made than to separate the professional
interests of pharmacy and the commercial interests of
chemists and druggists, and in speaking last week of “ those
responsible for the protection of the professional interests of
pharmacy,” refereoce was made to men whose constant care
is the prosperous development of pharmacy in every legiti¬
mate direction. We recognise no antagonism between the
professional and commercial interests of the craft.
The two are inseparably connected, and it is because
of the tendency to trust implicitly in the predominant
importance of commercial interests that it becomes necessary
on occasion to give timely warning of the rocks ahead. The
chemist and druggist who best safeguards his professional
interests runs least risk, on the commercial side, of having
wrested from him advantage over other tradesmen.
It would not, perhaps, be quite reasonable to expect from
the Secretary of the P.A.T.A. complete acquiesence with our
views on this subject, nor do we begrudge him any consola¬
tion he may derive from his own interpretation of our
remarks upon it. But we must remind him that our desire
is to maintaiu, as far as possible, a strictly impartial position
as to the work of the P.A.T.A. While sympathising with
the principle of its efforts to remedy evils arising mainly
from that part of the chemist’s business which Mr. Hyslop
describes as the “ quack medicine trade,” it is impossible to
ignore the decided disapproval with which many regard the
means adopted for that purpose.
496
PHARMACEUTICAL JOURNAL.
[June 5, 1897
ANNOTATIONS.
The Benevolent Fund Special List has been extended by
the addition of several more names, but the total amount received
or promised is yet far short of two thousand five hundred pounds.
It has been decided, however, to keep the list open until the end
of June, when a further list of donations and new or increased
annual subscriptions will be published, and by that time, it may
be hoped, the desired total will have been attained. Meanwhile,
readers should bear in mind the fact that Mr. Richard Bremridge
is prepared to receive large or small sums for the pharmacists’
insurance fund at 17, Bloomsbury Square, W.C.
The Herbarium Prize offered by the Council of the Pharma¬
ceutical Society for the best herbarium collected in any part of the
United Kingdom, the Channel Islands, or the Isle of Man, between
January 1, 1896, and July 1, 1897, will be awarded at the Council
meeting in August next. Competitors must be subscribing
“students” of the Society, and their collections must be forwarded
to the Secretary so as to arrive not later than Thursday, July 1.
Botanical students, please note !
Sheriff Mair as a Pupil is distinctly amusing, but it is also
highly gratifying to find that his education is progressing apace,
and that his ideas respecting the objects of the Pharmacy Act and
the duties of a petty judge are becoming much clearer (see p. 501).
He has long given the impression that one of his chief desires was
to preside at the hearing of a charge against a chemist’s assistant.
At last he has been gratified in the matter, and although he is
still far from running smoothly in the judicial harness, he
has acknowledged that he is not entitled to express any
opinion of his own, and therefore bound to deal with the
evidence as it is laid before him. Such modesty and self-efface¬
ment are stupendous, and bring with them suspicions of the
atmosphere of a millennial law court, if the possible existence
of such a place may be assumed. The fact of the matter is
that for once the Sheriff has proved an exponent of the law as it
is, rather than as it ought to be, and if he will only continue in
the same path we may hope to see penalties that are more than
nominal imposed in due course at the Airdrie Sheriff Court, even
at the hands of Her Majesty’s present representative, as a dispenser
of justice. -
A Public Analyst’s Omission to carry out strictly the formalities
stipulated by the Sale of Food and Drugs Act, was the cause of a
case against a Dowlais chemist being dismissed on Monday last.
The alleged offence was selling tincture of cinchona not of the
nature, substance, and quality demanded by the purchaser, and it
appears that the seller had declined the offer of the purchaser to
divide the article in his presence. In such a case the duty
of the analyst receiving the sample, as laid down by the
Act, is that he “shall divide the same into two parts, and
shall seal or fasten up one of those parts, and shall cause
it to be delivered, either upon receipt of the sample or when he
supplies his certificate to the purchaser, who shall retain the same
for production in case proceedings shall afterwards be taken in the
matter.” What the analyst did was carefully to seal up an empty
bottle, and though defendant’s solicitor was quite prepared to
deal with the case on its merits, the Magistrate said it must fail on
the ground of informality. It is to be regretted that the nature of
the alleged deficiency in the tincture was not mentioned, and the
case gone into, as the report might then have proved instructive. It
was stated in court that there is no provision in the Act (sic) that
the tincture shall contain any specific quantity of alkaloids, but
inasmuch as the B.P. standard for red cinchona bark is that it
should yield between five and six per cent, of total alkaloids, it
might be contended that the tincture should contain not less than
one per cent, of total alkaloids. At any rate, such an assumption
would have served as the basis of an interesting argument.
Dr. Julius von Sachs, whose death we regret to announce, was
probably the most eminent man of science on the list of the Phar¬
maceutical Society’s honorary members. He was Professor of Botany
at the University of Wurzburg and a Foreign Fellow of the Royal
Society. He practically instituted a new method in the study
of plant life, by insisting on the necessity of dealing with plants
in a similar manner to other living organisms. As a result,
he took high rank as a teacher of world-wide influence. His
‘ Text-Book of Botany,’ ‘ Lectures on the Physiology of Plants/
and ‘ History of Botany ’ are already classics, and have supplied
the substratum of most botanical text-books now in use. Few
botanical workers have done more to advance the science, and his
death leaves a sense of profound loss.
The Report of the Pharmacopceia Committee of the General
Medical Council was presented to the Council on Thursday last,
and in this it is stated that the progress of the work of revision of
the British Pharmacopceia can be readily estimated from the draft
proofs which have been issued to the members of the Council.
These comprise the whole of the text of the volume, and the work
which remains to be done consists of the preface, the completion
of the appendix, and the preparation of the index. It is proposed
to place the modifications desired by the Colonies in the appendix,
and it is also proposed to alter the arrangement of the index
somewhat so as to include complete lists of official preparations
and also the doses. After the revised proofs have been received
from the members of the Council, the Pharmacopceia Committee
will meet again, and it is hoped that it may be possible to place
the completed volume before the Council at the meeting in
November next. If then approved, the order to print will prob¬
ably be given forthwith, and pharmacists may expect to have their
eyes gladdened by the sight of the new volume early in 1898. But
until that time, or later, their critical faculties must find exercise
in other directions. -
The Conference Blue List for the year is now being sent out,
and it is reprinted at page 487. Special attention is directed to
the request that manuscripts of papers should be sent in to the
Honorary Secretaries well in advance of the date of meeting. It
may also be pointed out that, until papers have been received by
the Honorary Secretaries and accepted by the Executive Commit¬
tee, authors are not entitled to assume that they will be permitted
to read their papers at the Conference. Papers accepted and read
become the property of the Conference, and are published later in the
‘ Year Book of Pharmacy.’ But to ensure accuracy in reports of the
annual meetings, the Honorary Secretaries are always prepared to
afford facilities to trade papers. It is quite unnecessary, there¬
fore, that authors should delay sending in their papers for the
sake of furnishing abstracts, etc., to anyone who may apply for
them, and to be quite in order, all applications for copies or
abstracts should be referred to the Honorary Secretaries.
A Medical and Pharmacy Act Amendment Bill is at present
before the Cape Parliament, and we gather from the Gape Times
particulars of the discussion that took place when the Legislative
Council went into committee on the Bill. An amendment was
proposed which would have allowed medical men to open chemists’
shops in any town or village where there is no chemist, but would
have prevented them doing so within five miles of an established
chemist’s shop. The matter was warmly debated and a variety of
June 5, 1897]
pharmaceutical journal.
497
opinions expressed with regard thereto, but ultimately the amend¬
ment was negatived without a division. This result should be very
gratifying to our brethren at the Cape.
The Annual Report on Alkali Works, for 1896, states that
the amount of salt decomposed during the year by the Leblanc
process shows a more considerable reduction than has occurred
since 1893. At the same time, the ammonia soda process shows
only a slight increase for the year, though it has largely increased
the lead over its rival, which it obtained for the first time in
1895. The figures in tons are : —
Process.
1S96.
1895.
1S94.
Leblanc .
360,929
431,577
408,173
428,614
434,298
Ammonia-Soda .
361,603
Total .
792,506
836,787
795,901
It will be observed that the relative positions in 1894 and 1896
are almost exactly reversed. There has not been much actual
addition during the past year to the manufacture of caustic soda
and chlorine by electrolysis. The work done has been chiefly
experimental in character, and various mechanical and chemical
difficulties have been experienced at St. Helens. But these diffi¬
culties are gradually being overcome, and it is stated that other
works will shortly be completed where electrolytic processes will
be put in operation.
Fluorine has at Last been Liquefied, and curiously enough,
M. Moissan, who first definitely isolated this element, appears to
have taken part in Professor Dewar’s latest successful experi¬
ment. On Friday, May 29, M. Moissan delivered a lecture on
the isolation of fluorine (see p. 499) in the lecture theatre of the
Royal Institution, and on the following day the liquefaction of the
element was brought about in the adjoining laboratory, at a tem¬
perature of - 185° C. A clear yellow and extremely mobile liquid
was obtained, and it is stated that this does not possess the
property usually associated with fluorine of attacking glass,
silicon, sulphur, or phosphorus, though it still attacks carburetted
hydrogen and seems to retain its affinity for hydrogen. The
apparatus employed for liquefying the gas was that rendered
familiar in Professor Dewar’s demonstrations. Whether the liquid
can be solidified remains yet to be seen.
The Edinburgh District Chemists’ Trade Association will
bold its annual picnic on Thursday, June 10, and the Committee
is hopeful that the charms of the interesting and historic part of
Scotland, which it is proposed to visit on this occasion, will
attract an even greater number than usual. The day’s proceed¬
ings will consist of a railway journey in saloon carriages by special
train to Selkirk. Brakes will then convey the party up Ettrick
Water to Tibbie Shiels’ Cottage on St. Mary’s Loch, sandwiches
being partaken of on the way. Two hours will be spent here, and
tea and other refreshments may be had by those desiring them,
either at Tibbie Shiel’s Inn or at the Rodona Hotel, where a very
fine view of the loch may be obtained. The brakes will then
return to Selkirk by the banks of the Yarrow, renowned in song
aud story. Dinner will be served at the County Hotel, and the
party will return to Edinburgh by train from Selkirk Station. The
price of tickets is 11s. each. Double tickets for lady and gentle¬
man, 21s. All chemists, and others connected with the trade, are
cordially invited, and the honorary secretary, Mr. Claude F. Henry,
1, Brandon Terrace, Edinburgh, will be glad to hear from any who
propose to attend.
Chemists who are Sub-Postmasters are combining to protect
their special interests as such, having resolved, at a meeting held
on Wednesday afternoon, May 26, at the Tweedale Restaurant,
Manchester, to join in forming a Manchester and District branch
of the National Federation of Sub-Postmasters. Amongst those
present were Mr. Breadner, chemist, Cheetham Hill ; Mr. Foden,
chemist, Chorlton-cum-Hardy ; Mr. Wilkinson, chemist, Man¬
chester; Mr. Inglis, chemist, Delph; and Mr. Cussons, chemist,
Ossett. Mr. Morton, of Bury New Road, was voted to the chair,
and stated that he had received about fifty letters regretting inability
to attend, and promising to join a society if formed. After short
addresses from Mr. Ranns, of Wakefield (President of the National
Federation), Mr. Cussons, of Ossett (Honorary Secretary), and
Mr. Inglis (Vice-President), a resolution was carried unanimously
to the effect that a local association should be formed and affiliated
with the National Federation. A committee was elected, and
steps were taken to meet at an early date.
Costly Faith in Water Divining has been manifested by the
Urban District Council of Ampthill, Beds, for at the audit
meeting several ratepayers objected to expenses which had been
incurred in the employment of a water diviner. The audit was
adjourned for the attendance of the members of the council who
had authorised the payments, and when those gentlemen appeared
before the auditor they expressed their firm belief in the powers of
the diviner. They explained that the diviner had located several
places where water would be found, and that the council had
applied to the Local Government Board for a loan with which to
carry out the boring there. On the other side it was alleged
that the reports of the Geological Surveyor to the Govern¬
ment showed that a proper supply of water could not be found
where the diviner had indicated its existence. Ultimately, after
a long hearing, the auditor announced that he would surcharge
the councillors with the payments which they had authorised, as
in his opinion local authorities were not justified in spending
public money in the employment of persons professing to exercise
powers of this kind. The councillors had not succeeded in con¬
vincing him that, after having obtained the report of the diviner,
they knew anything more than was previously known of the
water-bearing properties of the locality. As the courts had held
that the pretence to a power, whether moral, physical, or super¬
natural, was illegal, he was bound, in the interests of the rate¬
payers, whose money was taken from them under threat of
distress of their goods, to see that such moneys were not expended
on such enterprises as water-divining. And so science triumphs
once more over superstition.
The Secretary of the Attfield Testimonial Committee
asks us to state that the funds received are now sufficient, but
autographs are still invited. Eleven hundred names have already
been received, and these, with any others that may be sent in,
will be alphabetically arranged in an illuminated album containing
an address. With these signatures will be incorporated at least
one hundred autographs of Dr. Attfield’s compeers and other
public friends in Great Britain and Ireland, India, the Colonies,
the United States, and the chief cities of Europe. It will be a
handsome volume, twenty inches by sixteen, and two or three
inches thick, and with this will be presented a large silver tray
and a complete silver tea and coffee service. The portrait by
Professor Herkomer is now completed. It shows a three-quarter
side face, is almost life-size, occupies the greater portion of a
plate fifteen inches by eleven, and is being printed on stiff" paper
twenty-seven inches long by over twenty inches wide. It is a
capital likeness and finely executed.
498
PHARMACEUTICAL JOURNAL.
[June 5, 1897
NOTICES OF BOOKS.
Green’s ‘ Manual of Botany,’ volume I. ( J. and A. Churchill,
London, 7 s. 6 d.), has reached a second edition, but this appears so
soon after the first edition that but few changes have been
required in the subject-matter of the book, and only six pages are
added. We learn from the preface that the chapters on morpho¬
logy have been revised and in some parts compressed, the section
on the inflorescence has been re-written, and that on the sexual
reproductive organs has been re-arranged in view of two years’
experience in teaching since the adoption of the work as the
text-book at the School of Pharmacy. Book II., which deals
with the anatomy of plants, remains practically the same as in the
first edition. The general index has been extended from less than
three pages to seven pages, and now partakes of the nature of a
glossary, a useful alteration. On the other hand, the index of
plants, which formerly occupied nearly five pages, is now com¬
pressed into three. There is, however, no apparent disadvantage
in this. The book will doubtless continue to be “ the ” text-book for
pharmaceutical students, and it is to be hoped that the second
edition may have as brief a career as the first.
Wishart’s ‘Schedules for Plant Description’ (E. and S.
Livingstone, Edinburgh, 6d. net) have been planned on similar
lines to those in Holmes’ ‘ Botanical Note Book,’ but they allow of
much fuller treatment than is possible in the latter on account of
the extra space devoted to the purpose. On the left-hand page
the student is expected to insert the consecutive number of
the specimen examined, followed by the date of examination,
and then proceed to describe the habit of the plant, its
root, stem, leaves, inflorescence, bracts, flower, perianth,
calyx, corolla, andrcecium, and gymecium. On the right-hand
page are roomy spaces for describing the fruit, seeds, and habitat ;
inserting the floral formula ; sketching the floral diagram and a
vertical section of the flower ; and other spaces for miscellaneous
remarks and reasons for classification and name. There are thirty
schedules, and at the end of the book two pages are provided for
an index of contents. The wallflower is taken as an example to
show how the schedules should be filled up, and students who go to
work systematically on this plan should attain a very fair knowledge
of the morphology of plants. The author, by the way, is an old
pharmaceutical student, and gained the Pharmaceutical Society’s
herbarium medal in 1894. He has since been studying the arts,
sciences, and medicine at Aberdeen University, and is now lecturer
on zoology and general biology at Robert Gordon’s College.
Waring’s ‘Bazaar Medicines of India’ was originally
published at Travancore, in 1860, with the view of putting the
district vaccinators of Travancore in possession of the knowledge
of means by which they might alleviate pain and cure diseases
in regions where regular medicine was not procurable. In that
edition the text was printed in English and Tamil on opposite
pages. Fourteen years later Messrs. J. and A. Churchill
published a second edition in English only, and now the fifth
edition makes its appearance from the same publishers (price
5s.). This has been issued by the author’s son, Mr. C.
Waring, with the assistance of Dr. J. E. T. Aitchison, C.I.E.
The introduction treats of weights and measures, and also
includes hints on the preparation of infusions, decoctions, tinctures,
pills, ointments, etc., for the use of readers who may be wholly
ignorant of matters pharmaceutical, or only partially acquainted
therewith. Then follows an alphabetical list of the bazaar
medicines and Indian medical plants included in the work. A
brief description of each is accompanied by a list of its numerous
native names, and following this we find particulars of the
properties of the drug and of the affections in the treatment of
which it may be usefully employed. Part II. is a synopsis or index
of diseases, reference being made in each case to the appropriate
remedies. Appendix A consists of directions for restoring
the apparently dead from drowning ; B is a summary of
treatment of persons bitten by venomous snakes, and pre¬
cautions to be observed by persons residing in snake-infested
localities ; 0 describes the method of treating small-pox
by means of carbolised oil. The clinical thermometer and its use
receive attention in appendix D, and a few European medicines
for which the Indian bazaars supply no adequate substitutes are
referred to in appendix E, which also includes a list of articles re¬
quired for carrying out the directions in the book. The object of
the work is to show how much good may be effected by the simple
means at command at almost every “ up-country station ” in India,
and it seems well adapted to secure the realisation of that object.
‘Reagents and Reactions Known by the Names of their.
Authors ’ is a reprint from the Pharmaceutical Review, of Mil¬
waukee, Wis., and consists of an English translation by R. Fischer
of Dr. Julius Altschul’s “Nach Autoren benannte Reactionen und
Reagentien,” which appeared originally in the Pharmaceutische
Centralhalle. The list— which consists mainly of reactions and
corresponding reagents for qualitative tests, with a few of the
more important bacteriological reagents — is published by the
Pharmaceutical Review Publishing Co., Milwaukee, Wis., U.S.A.,
at 50 cents, and should prove extremely useful. It is proposed to
republish the list in an extended form in the Pharmaceutical
Journal, commencing this week.
‘ Summer Tours in Scotland ’ is the title of a little book, the
subject-matter of which is particularly attractive now that the
wintry weather seems fairly behind us, whilst in view of the fact that
the district described is likely to be visited by many pharma¬
cists in August next, the book possesses special interest to
them. It is beautifully illustrated and furnished with excel¬
lent maps by Bartholomew, in which the routes of the
numerous excursions described are plainly indicated. There is a
capital service of steamers leaving Glasgow daily (Sunday always
excepted) during the summer, and conveying passengers to Oban,
Staffa and Iona, Fort William, Inverness, Skye, Gairloch, etc. The
trips may be for the day only or extended over a longer period as
desired. Full information how to proceed and as to what may be
seen is contained in this official guide book, which is published
by Mr. David Macbrayne, 119, Hope Street, Glasgow, at the very
moderate price of sixpence. Those who propose to attend the
Conference should certainly see the book, and those who do not
may possibly be tempted to go after dipping into its pages.
A General Index to the ‘ Analyst ’ has just been published by
Bailliere, Tindall and Cox, London, 16s. nett, and covers a period of
twenty years. It has been compiled by J. C. Welch, is arranged
in a convenient form, and so far as type and paper go, is
a vast improvement on indexes generally. The book will
be found exceedingly useful by everyone who may need
to refer to the back volumes of the Analyst, and such as are
also readers of the Pharmaceutical J ournal — not a few in number —
will probably feel more forcibly than ever the inconvenience of
not having a general index to its last twenty volumes. But that,
of course, is quite another story.
June 5, 1897]
PHARMACEUTICAL JOURNAL.
499
MEETINGS Of SCIENTIFIC SOCIETIES
- + -
Royal Institution, Friday, May 28.— There was a crowded
audience, including a large number of ladies, to hear a lecture
delivered by M. Henri Moissan, who spoke in French, upon
The Isolation of Fluorine,
and the interest evinced by the audience showed that the lecturer
did not lack the power of lending new attractions to a subject
already familiar. M. Moissan commenced by discussing the history
of fluorine, mentioning the more noteworthy methods used in the
attempt to isolate the element. The first obstacle chemists had
been compelled to face was the energetic action of hydrofluoric
acid upon all materials from which suitable apparatus could be
made. Allusion was made to the experiments of Lavoisier and
of Davy, the latter of whom had partially overcome this difficulty
by using apparatus made of fluor-spar. Acids of greater and
greater concentration were from time to time obtained, yet no effort
had been successful in separating the elements entering into its com-
osition. Gay Lussac was the first to disprove the original idea that
ydrofluoric acid was a compound of oxygen, but for many years
the element whose properties were very well known in combination
remained unisolated. Chemical methods analogous to those by
which the halogens are obtained failed to isolate the substance for
reasons that are now obvious, seeing that the chemical activity of
fluorine is so great, and for a long time electrolytic experiments were
equally abortive. If a concentrated solution of hydrofluoric
acid was electrolysed, at first hydrogen was set free at the nega¬
tive pole and oxygen at the positive, the water being virtually
electrolysed, for as is now known, fluorine attacks water so ener¬
getically that when formed at the pole it instantly reacts with the
water present, forming hydrogen fluoride and setting free oxygen ;
afterwards when the passage of the current is continued until all
the water is decomposed the current is completely stopped, owing
to the exceedingly low conductivity of anhydrous hydrogen
fluoride. Another difficulty was met in the fact that the electrode
was in every case attacked by the nascent fluorine. Among the
chemical methods tried in the hope of isolating fluorine was the
action of oxygen upon the fluorides of phosphorus. M. Moissan
had succeeded in preparing an oxyfluoride of phosphorus, the
existence of which rendered probable the possibility of obtain¬
ing fluorine in this way. Nothing, however, was achieved from
any of these methods, and M. Moissan soon became convinced that
the solution of the problem was to be looked for in an electrolytic
method. Arriving at the description of his successful experiments,
the lecturer proceeded to sketch on a blackboard a section of the
apparatus used for isolating fluorine. This consisted of a platinum
U-tube, closed by stoppers of fluor-spar through which wires
were admitted to the electrodes. The tube was filled with
carefully dried hydrogen fluoride, to which potassium fluoride was
added to render it a conductor, and the tube being surrounded by
a freezing mixture, a current from about twenty Bunsen’s elements
connected in series was passed. The fluorine produced was delivered
into the air by a narrow platinum tube. Platinum serves well as
a receptacle, as it is only attacked by fluorine at a high tempera¬
ture, but for the electrode at which the fluorine is produced it is
necessary to use an alloy of platinum and iridium, which resists
the corrosive action better. With such an apparatus M. Moissan’s
assistants prepared a quantity of the gas, while he himself
demonstrated some of its chief properties. Its effect on crystalline
silicon was first shown, the silicon instantly bursting into flame
when a stream of the gas was allowed to impinge on it. Silicon,
it was pointed out, forms a useful reagent for the detection of
fluorine, the ignition of the silicon and formation of a gaseous
fluoride being characteristic. Its action upon phosphorus, sodium,
boron, and iron, was then shown ; in each case the substance
glowed with the heat of reaction. In general, metals are attacked
less rapidly than other elements, for the reason that a protective
coating of fluoride is formed upon the surface. It is no less
energetic in its action upon organic bodies ; benzene was instantly
set on fire when brought to the mouth of the tube from which the
fas was issuing, and a taper was also kindled in the same way.
erhaps the most striking effect was that produced on carbon,
which was made to glow brightly by the action of the gas.
When potassium iodide is treated with fluorine, iodine is first set
free, but this at once unites with more fluorine to form a trifluoride.
The method of determining its density was also described and the
apparatus shown. It is weighed in a platinum bottle, which is
filled with the gas by means of a tube passing to the bottom, the
air which is thus displaced passing out by a side tube at the top.
The bottle is known to be full when the issuing gas ignites silicon,
and after the two openings of the bottle have been closed by
accurately-fitting stoppers it is ready for weighing. Among the
apparatus set upon the table for inspection was a tube of platinum
closed at the ends with transparent plates of fluor-spar and pro¬
vided with a side tube at each end, by which it could be filled, the
air being displaced. By means of this tube the effect of reactions
may be watched. When filled with fluorine the greenish-yellow
colour of the gas is distinctly visible in a good light. The colour
is somewhat like that of chlorine, but fainter and yellower. By
causing fluorine to react with water in the tube, ozone is produced
of such a concentration as to render visible the blue colour ascribed
to it by MM. Hautefeuille and Chapuis.
Royal Society, Wednesday, May 19. — The conversazione held
on this date, a brief report of which has already appeared, was the
first of the two held annually by the Society, and a more
detailed account is now given of the exhibits. The first entered
on the catalogue was a selection of
Photographs in Colour
obtained by the Dansac-Chassagne process. A high standard of
excellence appears to be obtainable by this method, the colours of
natural flowers and dress fabrics being faithfully reproduced. All
that is known of the process is that a silver print is treated with a
succession of colouring materials from which it is alleged to
abstract selectively the tints proper to their respective positions.
A colour photograph was shown in its successive stages of develop¬
ment. After the first treatment it appeared all blue, after the
second it was tinted in places with green, and after the third,
yellow and red made their appearance, all the colours showing
clearly, and being properly distributed.
Physical Apparatus
predominated among the exhibits, and the next thing to attract
attention was an electrical apparatus. It consisted of a powerful
coil, to which was fitted, in addition to the usual terminals for
sparking, a pair of knob terminals separated by a dish containing
a soft mixture of resin and oil. When sparks were passed between
the former set of terminals the viscous fluid resting between the
latter was thrown up in the form of a cone with a hollowed apex
by the electrical stress. Discs of resin were also shown which had
been subjected to this stress, and afterwards softened by heat to
allow the figure to develop. If while the disc is soft it is placed
in a cloud of dust, the particles are attracted to the electrified
regions and a figure is obtained, characterised, according as it was
charged, positively or negatively on that side. Among other
electrical apparatus was
A Large Induction Machine
exhibited by Mr. Wimshurst. The special feature of this machine is
that it is composed of twenty-four plates of 3 feet diameter, and is
arranged to give three poles, two of which are positive, and the
remaining one negative or vice-versd , so that two streams of
discharge can be used at the same moment. While the current
produced by this machine is of only a few amperes the potential is
very high. It gives a spark of thirty-four inches in air ; and
it is found that ordinary Leyden jars or gutta-percha covered wire
do not serve for use with this machine, being constantly liable to
penetration by the charge. A new apparatus for estimating the
relative values of explosives was shown by Sir A. Noble. By this
apparatus the pressure due to explosion at any given instant
after ignition is shown by means of a curve traced on a revolving
drum. Some results of
The Agricultural Researches
of Sir J . B. Lawes at Rothamsted were exhibited by Dr. Arm¬
strong. Hitherto the results have always been supplied in figures;
now these are replaced by diagrams, which are more favourable
for drawing comparisons.
The Extinct Naguada Race,
inhabiting Egypt about 3000 years B.C., whose remains have lately
been brought to light, were described, and a collection of bones
from about two hundred of their skeletons set out for inspection
by Mr. E. Warren.
500
PHARMACEUTICAL JOURNAL.
[June 5, 1897
Some Zoological Fossils.
brought from Madagascar by Dr. Forsyth Major, were exhibited
by the discoverer. Among them were a fossil monkey of entirely
new genus and species, and a restored skeleton of Alpyornis
hildebrandi (Burckhardt), an ostrich-like animal now extinct. The
egg of another species, Alpyornis maximus, exhibited by Dr.
Woodward, measured twenty-six inches in girth, and thirty-one
inches in longest circumference.
Photographs of the Moon
taken at Greenwich with the new Thompson photographic tele¬
scope were shown by the Astronomer Royal, and the photographic
atlas of the moon, published by the Observatory of Paris, was
lent from the library of the Royal Society.
Comparisons of Arc and Spark Spectra
show that certain lines are enhanced in passing from arc to spark,
and it has been shown that many of the lines in the spectra of
stars hitherto classed as unknown lines are identical with the
enhanced lines of known substances. Photographs of spectra
illustrating this were exhibited by Mr. J. Norman Lockyer.— From
Kew Gardens came
A Collection of Dried Plants
brought by Captain Deasy from his recent expedition to the lofty
table-lands of Tibet. These plants, growing at an altitude of from
15,000 to 19,000 feet, are characterised by a large development of
root, with an almost entire suppression of stem. — Among matter
of chemical interest were photographs illustrating
The Micro-Structure of Alloys.
These photographs show, as has been demonstrated in another
way by Professor Roberts Austen, that when fluid mixtures of
metals and non-metals are allowed to cool, crystals of definite
chemical composition are formed, and may be clearly seen with
the aid of the microscope, after the polished surfaces have been
etched with dilute acids or tinted with suitable reagents. Professor
Roberts Austen exhibited
An Apparatus for Micro-Photography,
which has been brought to such a degree of perfection that by its
means the condition in which carbon exists in steel can be clearly
shown. Under a magnification of 1000 diameters steel is seen to
contain minute particles of true diamond. Mr. C. T. Heycock and
Mr. F. H. Neville exhibited
X Ray Photographs of Sodium-Gold Alloys,
illustrating the results embodied in their paper recently read
before the Chemical Society. They also showed a curious colour
effect produced by heating an alloy of silver and zinc to over 300°
and suddenly cooling below 150°. The alloy, which is normally
white, then becomes superficially bright red.
Photographs of Optical Projections in Space
were shown by Mr. Eric Stuart Bruce. These photographs are
interesting as being obtained from an image w iich does not exist
as a whole, the camera having been made to retain and unite in
the same way as does the retina the various minute portions of a
lantern projection which appear on the revolving lath of the aerial
graphoscope, an optical instrument for producing these projec¬
tions, which was exhibited at a former conversazione of the Royal
Society. The image produced by the aerial graphoscope being
transparent to the eye, real objects standing before the camera
appear in the photograph through the transparent image. — Mr.
Guillaume, of the Bureau International des Poids et Mesures,
illustrated interesting facts relating to the great variation in
Expansibility of Nickel Steel
for different percentages of nickel. A compensated pendulum of
nickel steel was shown. — Dr. Norman Collie and Captain Deasy
showed
A Pocket Mercurial Barometer,
which consisted of a rubber tube joined at one end to a glass tap,
and at the other to a glass tube, in which the top of the mercury
column can be viewed. By closing the tap and coiling the tube
the barometer is capable of being packed in a small compass. The
reading is made by a folding pocket-scale. It has been used in
India with satisfactory results. — Professor Oliver Lodge illustrated
the important discovery of Zeeman, that the spectrum lines from a.
source of light, when acted upon by a magnetic field, are broadened
and in some cases even split up into two or more lines. — Some
pretty experiments in
Colour Phenomena
were shown by Mr. Shelford Bidwell. If while the eye is fatigued!
by a strong colour it is turned on a white ground, the complemen¬
tary to that colour is seen. A disc half black, half white, from
which a sector is cut between these two colours, is made to rotate
rapidly. A coloured object viewed through the rotating disc
appears of the complementary colour ; for example, a red rose and
green leaves appears as a green rose with pink leaves. The ex¬
planation is that while the eye rests on the black half of the disc
it becomes exceedingly sensitive ; it then momentarily receives the
impression of the object— an impression too brief to be observed—
and finally the negative after-image of complementary colour
appears on the white half of the disc.
Interesting to Rowing Men
was an ingenious apparatus shown by Mr. F. C. Atkinson for
indicating on a diagram both the style and horse- power of a rower
over a course of 500 strokes. This is effected by a pencil which
rotates with the oar and moves vertically as the pressure of the oar
compresses a spring. — Mr. J. E. S. Moore had
A Collection of Animal Forms
peculiar to Lake Tanganyika, which are believed to be the survivals
of an oceanic fauna which existed at some time in the region of the
lake. Other exhibits from the Dark Continent were specimens of
the tsetse fly and its parasite, the protozoon (Trypanosoma), which
Surgeon-Major Bruce has succeeded in proving to be the cause of
the deadly tsetse-fly disease or “ngana.” The work of the fly is
merely that of communicating the micro-organism from infected to
healthy animals. A similar parasite is found in the blood of the
rat in this country, but it does not produce the same fatal effects.
Lantern Demonstrations
were given by Professor J. B. Farmer, who showed micro¬
photographs illustrating nuclear division both in animal and vege¬
table cells, and by Professor Ayrton, who demonstrated some
electric and mechanical analogues.
LEGAL INTELLIGENCE.
PROCEEDINGS UNDER THE PHARMACY ACTS.
Prosecution at Airdrie.
At the Sheriff Court House, Airdrie, on Friday, May 28, the
case of Bremridge v. John Young, Stirling Street, Airdrie
(see ante page 414), came before Sheriff Mair for trial.
Mr. T. B. Morison, advocate, Edinburgh, and Mr. Robert Watt,
solicitor, Airdrie, appeared for the prosecutor, and Mr. William
Orr, solicitor, Coatbridge, for the defender.
Mr. Rutherford Hill said the information supplied to the
Registrar had been placed in his hands by the Registrar, with
instructions to institute proceedings, and he received the purchases —
a box of red precipitate ointment, and a bottle of “Balsam of
horehound and chlorodyne ” from Mr. Brock, solicitor,
Bath Street, Glasgow. On analysis he found that the
former contained about 30 grains of red oxide of mercury
and the latter about half a grain of morphine, and not less than 10
minims of chloroform. The bottle was labelled “John Harvie,
chemist and druggist, Stirling Street, Airdrie.” The purchases
had a sealed docket attached to them bearing the signatures of
James Lees and Jane Lees. He produced the Register, showing
that defender was not a registered chemist. In cross-examination,
witness said the bottle and the box might easily have been opened
without breaking the seal, and it would have been possible to
tamper with the contents. Both were full when he got them from
Mr. Brock’s clerk, and there was no evidence of tampering with
them.
The Sheriff : This complaint is brought under Sections 1 and 15
of the Act. Does the respondent come under the latter Section ? —
Yes, my Lord.
The Sheriff : In what way does he “keep open shop ” ? — He sells
poisons.
June 5, 1897
PHARMACEUTICAL JOURNAL.
501
The Sheriff : He is charged with selling by retail. Did he sell
by retail ? — I believe so.
The Sheriff : Did he get the benefit of the sale ? He is called
the assistant to John Harvie ; do I understand that the shop
belongs to John Harvie ? — I have no information on that point.
•John Harvie is a registered chemist.
The Sheriff : Then, do you mean to say that a man who is only
an assistant in the shop, and who sells a preparation containing a
poison, falls within the Act ? — Most emphatically yes.
The Sheriff : Can you give me a case of that ? — Yes, I have had
•a great many such cases.
Mr. Morison : I may just refer your Lordship to the case of
Wheeldon in the Queen’s Bench reports. That was a chemist’s
assistant. But this is a matter for argument, and I shall argue
that point at the conclusion of the case.
Mr. Brock, writer, Glasgow, proved receiving the poison in this
•ease from Dr. Arthur in presence of the witness Lees and his wife.
He sent them to the Pharmaceutical Society in the same condition
as he received them, and they were in no way tampered with. In
•cross-examination, the witness said he could say positively that
the purchases were in no way interfered with up till the time they
were sent by his clerk to Mr. Hill in Edinburgh. Asked what
interest he had in this case and why these articles passed through
liis hands, witness declined to answer.
Mr. Morison said he objected to this line of inquiry, as these
questions had no bearing whatever on the case, and were alto¬
gether irrelevant.
Mr. Orr said these cases were brought in the public interest,
--and he wanted to know what interest this party had in this par¬
ticular case.
Mr. Morison said this person might have had ever so strong an
animus, or might have had a bad motive in giving this information.
He had nothing whatever to do with that, and the evidence must
•be judged as it stood.
The witness said he had got up this case for Dr. Arthur, to show
that the statements he made in recently defending the lad Lees
before his Lordship were perfectly true, and he thought the motive
dn doing so was a perfectly legitimate and good one.
Charles Simpson, clerk to Mr. Brock, proved handing the
.poisons to Mr. Hill in Edinburgh.
Dr. Hugh Arthur said he remembered Mr. and Mrs.
Lees coming to him with a box containing the poisons
on February 13 last, and he identified the productions
now shown to him. He affixed the seals to them, and saw the
labels signed in presence of his shopman and the purchasers.
He kept them in his safe, and they were never opened. He
handed them to Mr. Brock just as he received them. Red oxide
of mercury was a dangerous poison, and so was the chlorodyne in
the bottle. In cross-examination witness admitted that he was a
.party to the getting up of this case. Statements had been made
in the public prints by Councillor Harvie, and in a letter sent to
the Town Clerk, about his preparing medicines for the hospital, an
attack had been made upon him, and he must defend himself. His
shop-boy had said that Harvie’s people were doing this sort of
thing as much as anybody else, and he wanted this to be known.
Mr. Morison said he must repeat his objection to this sort of
thing being gone into.
Mr. Orr said Dr. Arthur was getting on beautifully. Ho was
showing the motive.
James Lees, miner, Airdrie, and his wife, spoke to purchasing
the poisons. They did not see Harvie in the shop. He might have
been in the back shop, but defender alone conducted the sales.
Thomas Russell, clerk to Motherwell and McMurdo, solicitors,
clerk to Airdrie School Board, proved that John Harvie was
present at a meeting of a committee of the School Board at the
hour when the purchases were said to have been made.
James Bain, assistant to Dr. Arthur, said he witnessed the
labelling and signing of the productions, which he now identified.
This was all the evidence, and no witnesses were called for the
defence.
Mr. Morison said both charges had been clearly proved. It was
-very unfortunate that there should be feeling or irrelevant matter
of a personal kind introduced into this case, and these matters
effected the Public Prosecutor neither one way nor the other. It
had been suggested in various ways, and remarks had been made in
that Court on previous occasions, implying that these prosecutions
were not dictated by regard to the public interest, and that certain
suspicions attached to the prosecutor. He wished to say most dis¬
tinctly that nothing of that kind entered into the Registrar’s duty in
enforcing the Statute. This Act applied to England, where there
was no Public Prosecutor, and as was most natural, the Legislature
had imposed that duty on the Registrar appointed by
the Pharmaceutical Society in pursuance of the pro¬
visions of the Act, and it was only what would
be expected, that the prosecutor appointed in accordance
with the procedure in England should also be the prosecutor in
Scotland, in an Act applying to Great Britain. But the
Pharmaceutical Society was not a trading society. It was
essentially a licensing and administrative body, and as a matter
of fact a great many registered chemists did not belong to it at all.
The Registrar was a public officer, and he was, as the servant of
the public, bound to institute prosecutions for infringements of
the Acts, and the moment he received information, no matter from
whom and no matter who the alleged offender might be, he was
bound to make inquiry, and if necessary institute proceedings.
In addressing the Court therefore, he (Mr. Morison)hadto do so only
upon the evidence and not upon matters of a personal kind that
had been introduced by the defender. That an unqualified
assistant in a chemist’s or doctor’s shop who sold poisons himself
without supervision was liable under the Statute was clearly
settled by the dictum of Lord Selborne in the London and Pro¬
vincial Supply Association case, and in the Wheeldon case in the
Court of Queen’s Bench, and the Tomlinson case in the High
Court of Justiciary. It had been attempted to bring out in the
cross-examination that Mr. Harvie superintended these sales, but
Mr. Harvie was not called as a witness, and there was not
the slightest evidence that he was present, and none of
the witnesses saw him, and it was shown that he was at
a School Board meeting at ten o’clock, and the poisons were
sold at twenty minutes past ten. He quoted Justice Hawkins’
definition of personal supervision, to show that mere
presence in the back shop or somewhere else in the premises was
not enough. All the evidence went to show that defender alone
sold the poisons, and that they were handed to Mr. Hill exactly in
the condition in which they had been received from defender. As
several cases had already been decided in that Court, he submitted
that justice could not be done in this one unless the full penalty
provided by the Statute was imposed.
Mr. Orr said he admitted that the Society had no other course
open to it than to bring this prosecution, but there were
motives in bringing it which he questioned very seriously — the
motives of the parties who had been acting behind the scenes in
this case. He thought their motive could not be too strongly con¬
demned, being one of spleen, which they had carried out to the
bitter end. He thought the fact that the chief witness had been
sent by Dr. Arthur to the shop for the purpose of getting a sale
should be enough to taint the whole of the prosecution. Dr.
Arthur had tried to conceal the fact that he instigated these pro¬
ceedings, and he was sorry to say he believed Dr. Arthur was
quite capable of tampering with the purchases while they were in
his possession. He thought the case had completely broken down
on the evidence. It had come out that these poisons had been for
weeks in the hands of interested parties, and that they had been in
London, and he submitted that they could have been tampered with
and poison put into them. The prosecutor had also failed to prove
that Mr. Harvie was not present when the sales took place, and he
submitted that the prosecutor to establish his charge must prove
that Harvie was not in the shop. He also submitted that Section
16 of the Act indicated that so long as the owner or manager of a
shop was qualified the assistants did not need to be qualified.
Mr. Morison said the provision in Section 16 was intended to
protect the trustee of a deceased chemist against prosecution for
putting up the title chemist and druggist or keeping open shop.
It did not touch the fact that only a qualified person could sell
poisons either in a deceased chemist’s shop or anywhere else.
The Sheriff said whatever his own opinion was as to the
Pharmacy Act 1868, and in particular Section 15, he must hold
himself bound by the decisions quoted by Mr. Morison in the
highest court of the realm, and also in the supreme courts of
England and Scotland, namely, as to whether the assistant of a
duly qualified chemist falls under Section 15, and in view of these
decisions there could be no doubt that a person in the position of
the defender, although in the employment of a duly qualified
chemist, if he sold an article containing poison, fell under the
Act. He was not entitled to express any opinion of his own, and
that being the case, he was bound to deal with the evidence
as it had been laid before him. There was no doubt
whatever that the poisons were sold by the defender, and
502
PHARMACEUTICAL JOURNAL.
[June 5, 1897
he differed from Mr. Orr in his argument that Mr. Harvie,
being a qualified chemist under the Act, the burden of proving
that he had not been present superintending the sale lay with the
prosecution. He had from the nature of the cross-examination
anticipated that Mr. Harvie would have been examined as a witness,
but he had not, and he was not entitled merely to conjecture it in
the face of the evidence otherwise. If it had been proved that
Mr. Harvie was in the shop and behind the partition, he would
have had difficulty in finding the case proved, and he doubted if
any court would convict in such a case. But he must hold
that he was not present. He did not think that in
a case like that they had anything -to do with the motives
that had led to the prosecution. No doubt they were open to
observation, but although the motives might so far affect a judg¬
ment in certain cases, in a case of that kind he did not think they
could do anything of the kind where these sales had been clearly
proved. As to the argument of the continuity of the possession of
the articles intact, he had no doubt in the matter, there having
been no evidence to show that they had been tampered with. If
Mr. Harvie had appeared and given evidence that the contents
were now different from what he sold he might have given effect
to that statement. He had been disappointed that Mr. Harvie
had not been examined, and if he had, it was possible
that the prosecutor’s coach might have been upset. But
he had to consider not negatives but affirmatives, not possibili¬
ties but realities. He was not entitled to deal with possibilities
where positive evidence should have been given. He must there¬
fore find the charges clearly proved. On the question of penalty
he did not agree with Mr. Morison, and he thought it would be
sufficient to impose a penalty of 5s. for each of the two offences
and allow 10s. of expenses.
EXTRACTS FROM CONSULAR REPORTS-
Canadian Apatite is a most eligible material for the manufacture
of a concentrated superphosphate, and the occurrence of workable
areas of apatite is known to cover a very extensive area in the
Laurentian system of the provinces of Quebec and Ontario, but
those which have been worked to date are confined to the county
of Labelle in Quebec and to the counties of Lanark, Leeds, Fron-
tenac, and Renfrew in Ontario. During 1878-95 297,342 tons,
valued at over $5,000,000, have been exported. The quantity
exported in 1895 was 4189 tons, or about one-fourth of the average
of the previous eighteen years. The decrease is due to Algerian
and Tunisian phosphates having secured the market.
“ Coccus Rusci,” the parasite of the fig, has of late attracted
much attention in Italy. It is an insect which is especially partial
to the fig, but is also found on other trees. The diameter of a well-
developed female is five millimetres, their colour is a greyish-white,
and they have the appearance of small cones upon the trunk and
boughs of the tree. They cover themselves with a special sub¬
stance like wax, which protects them. If this is removed with a
needle, the true colour beneath is seen to be a shiny" reddish-
brown, this being the creature’s true cuticle. Raising this skin, a
vast number of eggs will be observed (if the operation is performed
towards the end of June), these eggs being of a reddish-brown colour.
They become larvae in the month of July, and in a few days, when
they drive the proboscis into the bark, they manage to nourish
themselves from the tree. Once fixed, they undergo a strange
metamorphosis, for their legs drop off, their eyes disappear, and
their bodies exude the waxy substance which serves them as an
ultimate protection. No insecticide will affect them when once
they are duly encased ; but before that takes place they can be
killed by syringing the trees with a solution of petroleum and
soda crystals. This must be done as soon as the larvae appear,
and it will completely destroy them.
Artificial Wine. — According to a report from Naples, an im¬
portant scientific discovery has recently been made in Germany
in connection with the manufacture of wine. It has been
discovered that by a very simple process “ barley may be made into
excellent wine, having the character of port. The barley having
been malted, the bacilli of port wine are introduced into the mead
when they fecundate incontinently and transform it from immature
beer into the richest port wine. When the animalcuhe have done
their work they can be sterilised, a sufficient stock of microbes
being preserved in the laboratory for further use.”
NOTICES TO CORRESPONDENTS.
All Communications for tha ‘ Pharmaceutical Journal ’ must
ba Addressed to the Editor, 17, Bloomsbury Square, London,
W.C., and not in any case to individuals supposed to
be connected with the Editorial Staff; no responsibility
can bs accepted unless this rule be observed. Communica¬
tions for the Current Week's Journal should reach the
Office not later than Wednesday, but news can bo Received
by Telegraph until 3 p.m. on Thursday.
Advertisements and orders for copies of tlie ‘ Pharmaceutical Journal must
be addressed to the Publishers, 5, Serle Street, Lincoln’s Inn, London, W.C.
Cheques and money orders should be made payable to “ Street Brothers.
Correspondents should write in ink, on one side of the paper only, and must
authenticate the matter sent with their names and addresses— of course nob
necessarily for publication. No notice can be taken of anonymous communications „
Drawings for illustrations should he executed twice the desired size ; clean
sharp lines being drawn with a pen and liquid Chinese ink. Shading by
washes is inadmissible. Photographs can be utilised in certain cases.
Names and Formula should he written with extra care, all systematic names-
of plants and animals being underlined, and capital letters used to commence
generic hut not specific names.
Queries addressed to the Editor will be replied to in the J ournal as early as-
possible after receipt, but it is not always possible to publish answers the same-
week as the queries are received.
LETTERS TO THE EDITOR.
The Brentford Lime Cream and Glycerin Case.
Sir, — I feel that Mr. Webber is deserving of every sympathy at-
the injustice done him by the Brentford Bench in depriving him
of his legitimate costs. We have lately seen two cases in which
Mr. Bevan’s certificate has proved to be incorrect, and it seems as-
if he instead of the defendant (as is usually the ease) was given the--
benefit of the doubt. The remedy is to be found in the suggestion
of Mr. Higgs, of Kingston, in your issue of the 22nd ult., namely,,
a defence union. There have been several convictions lately'
against chemists, such as the arsenical soap and lime juice and
glycerin cases, which would have been quashed had they been,
carried to a higher court. Let every chemist in business send his-
name to Tvl r. Higgs, anct let us have that unity and combination
which will prevent similar injustices.
Ealing, May 31, 1897. E. J. Strickland.
The Council Election.
Sir,— I venture to think that the letter of Mr. Hyslop on
the Council election, will be read by many with feelings of in¬
dignation. It seems impossible for a number of chemists, who by
being in a better position than many of their brother pharmacists,
to be able to understand what a struggle it is for many of us to
live even decent!} . They, with their West-end pharmacies, un¬
limited wealth around them, their extensive dispensing connections,
no “trade doctors” round the corner, can afford to taboo patent
medicines and sneer at the P. A.T. A. But the lines have not fallen
to all of us in such pleasant places. Take my own instance. My
business is a small one. My patent-house account last year was
£150. Now, sir, I ask you, can I afford to treat this branch
of my business with the contempt it may or may not deserve,
when there are two doctors in the village, both dispensing every
bottle of physic they can, when the grocers sell patents at cutting-
prices, when half-a-dozen little shops deal in a whole host of penny
lines ? I trow not, and I hail with delight any effort which
endeavours to increase my profits in a legitimate manner.
Personally, I decline to condemn the preparations which Mr. Hyslop
is pleased to include under the designation of ‘ ‘ quack medicine trade,”
and see no difference between a West-end chemist recommending
his antibilons pills over the counter and a man who spends thousands
on advei’tisements in the papers. A lot of the tirade against
the quack medicine trade is mere humbug. Until “ the gentle¬
men who have been the life and soul of pharmaceutical progress ”
condescend to the low estate of their less fortunate brethren and
to the inevitable trade nature of their business, the Pharmaceutical
Council and all its works will be ignored by a large majority.
These gentlemen do not object to the grocers and oilmen selling
their nostrums by the gross. They profess to be our friends, bub
June 5. U97]
PHARMACEUTICAL JOURNAL.
will not stir a finger to ensure us a fair profit. Heaven save us
from such friends ! They urge us to strive after the plums of the
profession, which will ever be out of the reach of many of us. No,
sir, we shall have to be content with the bread and butter, but let
them endeavour to prevent its being cut quite so fine. Then they
will not be at the bottom of the poll next time.
Potters Bar, May 31, 1897. H. B. Sharman.
Sir, — I should be glad to be allowed to reply to one or two mis¬
statements appearing in your correspondence columns last week
under the heading of “ The Council Election,” and also to refer to
some inferences drawn by you in your Editorial thereon. The
charge of fickleness and ingratitude brought by Mr. Leo Atkinson
against the electorate is well replied to by yourself. Mr. Atkinson,
however, thinks it degrading that so large a section of
the adherents of the Society see nothing derogatory in
■discussing and arranging with grocers, oilmen, and ironmongers,
the prices at which medicines shall be supplied to the public, and
in alluding to thi3 you say, “The question whether chemists and
druggists ought to recognise any right on the part of other trades¬
men to deal in such articles has been waived, and those who have
agreed that it should be left out of sight for the time being
have thus relinquished a position which they will find it
difficult, if not impossible, to re-occupy.” You at least, sir,
must know that the recognition of, at any rate, the legal right
of other tradesmen to deal in such articles is a case of
Hobson’s choice. The Pharmaceutical Society is impotent in
the matter of securing for qualified chemists the sole right to vend
medicines, whether proprietary or otherwise. So long as men,
whom Mr. Hyslop, I think rightly, describes as men who for many
years have been the life and soul of pharmaceutical progress, see
nothing derogatory in having direct business dealings with any
outside tradesman, be he grocer, oilman, or ironmonger, pro¬
vided he is prepared to pay the price for their proprietary articles,
it appears absurd to talk of the P.A.T.A. members as having
relinquished a position which they will find it difficult, if not
impossible, to re-occupy. That position has been wrested from
them many years since. You, sir, know this well, for nine
years ago you said [Ph. J. [3], xviii., 827), “It ought to be
"unnecessary to remind pharmacists that, in so far as they are
tradesmen, they must expect no advantage over other tradesmen.”
In your issue of January 9 last you explained truly why this
was so. Here is the explanation you gave : “ Manufacturers,
too, cannot be depended upon to trouble themselves much about
the rate of profit reaped by distributors. Their only anxiety
is to get their goods into the hands of the public, and they
consider it of little importance whether this is done by the
chemist or any one else so long as business is done. In the
end, therefore, the retailer must rely upon his own initiative.
If, however, he acts alone, he can effect but little, whilst
if he proceeds in accordance with a plan previously agreed upon by
the majority of those similarly situated benefit cannot fail to
ensue.” Referring to the work of the P.A.T.A., you said,
*( Probably not the least useful result will prove to be the awaken¬
ing or re-awakening of the chemists and druggists in districts
where local associations have been non-existent, as they realise
what a powerful weapon is lacking in their never-ending struggle
against the changing conditions of business.” You practically
admit that there is little ground for Mr. Atkinson’s fears
of the future Council of the Pharmaceutical Society being
elected, dominated, and its policy determined at the sweet
will of the Grocers’ Federation. The voting power will
always be in the hands of chemists and druggists, and the members
of the craft banded together as the Chemists’ Section of the
P.A.T.A. will take care to consult their own interests in phar¬
maceutical politics, and not those of any outside body of traders.
In your article appears the following extraordinary sentence : —
“ Nevertheless, members of the Society have undoubted reason
for alarm when a body, whose executive includes several indi¬
viduals whose only connection with pharmacy is a commercial
one, seeks to influence the election of those responsible for the
protection of the professional interests of pharmacy.” If that
statement means anything, it means that the Council exists only
for the protection of the professional interests of pharmacy.
A large section of the trade are withholding their support from the
Society because they say it refuses to recognise our commercial
interests as business men. Your sentence just quoted goes a long
way to justify their complaint. Our Charter states that the
Society exists for, amongst other things, the protection of our
601
interests as chemists and druggists. To the average adherent of
the Society commercial interests are more important than what you
refer to as “the professional interests of pharmacy.” When Mr.
Atkinson says ‘ ‘ that those have been threatened with difficulties
in obtaining supplies who could not conscientiously give direct
support to this movement,” he says that which is untrue. No one
has been threatened with such difficulties unless the minimum
prices fixed by the proprietors have not been maintained.
I am sorry that the result of the P.A.T.A. circular has so vexed
Mr. Hyslop. His letter affords most marked evidence of pique.
However, I do not think Mr. Hyslop, even in his great wrath,
would willingly state what is untrue, though it only concerns the
pharmaceutically fallen members of the P.A.T.A. If anyone else
had stated that “ that Association had for its chief object the
cultivation of quack medicine trade,” I would be compelled
to call it a deliberate untruth, but Mr. Hyslop has shown
all along either that he cannot or will not understand
what the Association, supported by so many members of
the Council upon which he sought a seat, really exists
for, that I am inclined to believe he really thinks there are
actually 2000 chemists who are foolish enough to band themselves
together with the chief object of cultivating the quack medicine
trade ! The voters who had so marked an influence on the last
Council election are anxious to see some interest taken by the
Council in pharmaceutical commerce. I trust that the well-being
of the Society is not seriously threatened thereby.
London, E.G., June 1, 1897. W. S. Glyn -Jones.
Sir, — In the hour of defeat one is apt to have morbid thoughts,
and even give expression to them. If Mr. J . C. Hyslop had had
the experience of the majority of ordinary provincial businesses
he would not so recklessly have abused an organisation whose chief
object is not “ the cultivation of quack medicine trade,” but merely
to secure a little profit for those who are compelled to supply a
public demand. The public will go to a chemist for “ patents,”
therefore they must be stocked. Ever since passing the Prelimi¬
nary examination I have subscribed to the Society, but pharma¬
ceutical progress through the “life and soul/’ men has not yet
even learned to stop company trading.
Lowestoft, June 1, 1897. A. H. Hinde,
ANSWERS TO QUERIES.
Special Notice. — Scientific , technical , legal and general information required
by readers of the 1 Pharmaceutical Journal* will be furnished by the Editor as far
as practicable , but he cannot undertake to reply by post. All communications must be
addressed (( Editor, 17, Bloomsbury Square, London, W.C and must also be authen *
ticated by the names and addresses of senders. Questions on different subjects should
be written on separate slips of paper, each of which must bear the sender s initials or
pseudonym. Replies will, in all cases, be referred to such initials or pseudonyms
and the registered number added in each instance should be quoted in any subsequent
communication on the same subject.
Soft Buffalo Hide. — The buffalo hide which you send
has been softened with glycerin, with which it is saturated,
[Reply to Verax. — 95/21.]
Situation in Bournemouth. — Your best plan is to advertise,
which you can do free of charge in the Journal under the heading
of “ Engagements Wanted.” [Reply to Quaestus. — 96/40.]
First Examination.-*- All the examination papers have been
published in the Pharmaceutical Journal. Any good school books
will serve your purpose. [Reply to W. B. — 97/3.]
Cash Book. — One of the best books of the kind is ‘ The Tax-
Payers’ Cash Book,’ published by the Income Tax Adjustment
Agency, 12 and 13, Poultry, Cheapside, E.C., at half-a-crown net.
See notice of the book in the Pharmaceutical J ournal for June 6
last. [Reply to R. C. J. — 95/37.]
Book on Tobacco. — Probably Dunning’s ‘Tobacco’ one of the
“ British Manufacturing Industries” series, edited by Bevan, and
published by Edward Stanford, 55, Charing Cross, price 3«. 6 <7.,
will suit you. You will find notes on the preparation and
determination of nicotine in the past volumes of the J ournal of the.
Society of Chemical Industry. [Reply to Qu-estor. — 96/22.]
504
PHARMACEUTICAL JOURNAL.
[June 5, 1897
Rectified Spirit of Paraffin. — In all probability petroleum
spirit or benzoline is meant. [Reply to B. G. R. — 97/8.]
Poison Book. — You are under no obligation to show the book
to police officers armed with no special authority, but it is hardly
politic to refuse in such cases. [ Reply to Poison Book. — 96/24.]
Books for the Preliminary. — Latin, English, and arithmetic
are the examination subjects. Any first-class school books will do.
[Reply to W. B. — 96/17.]
Brandy Substitute. — Do you mean a brandy flavour without
the alcohol, or a fictitious brandy? If the former, “ oil of wine”
will probably answer your purpose ; if the latter, see Cooley’s
‘ Cyclopaedia,’ new ed., vol. i., page 367. [Reply to B. S. — 96/38.]
Food for Diabetics, etc.— You will get all the information you
require as to gluten bread for diabetic patients from Messrs. Van
Abbott and Sons, 6, Duke Street Mansions, Grosvenor Square,
W.C. [Reply to E. A. T.— 96/2.]
Books for the Minor. — ‘British Pharmacopoeia, ’ Attfield’s
‘ Chemistry,’ Ramsay’s ‘ Elementary Systematic Chemistry,’
Southall’s ‘ Materia Medica,’ Green’s ‘ Botany,’ vol. i. ; Ince’s
‘ Latin Grammar of Pharmacy.’ These will form a good nucleus.
[Reply to Ambitious Student.— 96/25.]
To Bleach Dyed Hair. — If the hair is thoroughly dyed with a
silver or lead dye, it is practically impossible to remove the colour ;
if a vegetable dye, such as walnut-juice or pyrogallol has been
used, peroxide of hydrogen will bleach it, but it will not much
affect the metallic dye. [Reply to R. C. J. — 95,38.]
Ginger Wine Essence. — A licence is only required for any¬
thing which can be used as a beverage, and we doubt whether this
preparation can be regarded as such. However, you can easily
settle the point by submitting a sample to the Excise authorities.
[Reply to W. W. — 97/6.]
Alkaloids of Calisaya Bark. — These vary in percentage very
much. Howard has found trees growing together in Ceylon, which
contained quinine varying in amount from 3T to 9'2 per cent.
Calisaya bark contains quinine chiefly, then cinchonine, and but
little cinchonidine. Paul found in Madras bark 5 '22 per cent,
total alkaloids, consisting of 3 '86 per cent, quinine, 0'23 per cent,
quinidine, 0'3 per cent, cinchonidine, 0'43 per cent, cinchonine,
0'4 per cent, amorphous alkaloid. The South American calisaya
bark is equally variable as to the amount of alkaloid
present, and may contain from 1'5 to 5 per cent, of quinine.
[Reply to Old Subscriber. — 95/36.]
Balls for Dysentery, etc., in Lambs. — These are a very
crude preparation. The chief ingredient is chalk, about 60 per
cent, of the “ball” being composed of that body. There is also
some root sliced up very fine, about 5 per cent. This does not
appear to be any ordinary drug, and is probably some “herb” or
wild plant. There is also a distinct trace of zinc present, and at
least 10 per cent, of coarse sand. This last ingredient will show
you how roughly the ball is made. The red colour is ferric oxide,
and it is massed with soap, probably Castile soap. The zinc present
is equivalent to about 2 grains of zinc sulphate in the whole ball.
It may be an impurity, but would probably have a beneficial
effect. The ball contains no catechu or other vegetable astringent
matter. [Reply to Agricola. — 95/25.]
Miscible Fluid Extract of Coca. — Coca leaves in No. 20
powder, 12 ozs. ; tartaric acid, half an ounce ; proof spirit and
water of each equal volumes. Mix 10 ozs. of proof spirit with the
same quantity of water. Dissolve the tartaric acid in the mixture,
then damp the powdered leaves with a portion, let the moist
powder stind in a covered vessel for two hours, then divide it into
three equal parts, packing each into a small percolator. Pour the
rest of the menstruum on percolator No. 1, with a further quantity
of a mixture of equal volumes proof spirit and water. As soon
as a few ounces percolate through, turn this on to percolator No. 2,
and when that begins to percolate, pass this through No. 3. Add
more menstruum to No. 1 until it is exhausted, passing this through
No. 2 and so on ; the final percolate in No. 3 should measure
12 fluid ounces. [Reply to J. D. — 94/26.]
Bending Steel Tubes. — Weare obliged to a correspondent for sug¬
gesting that you should fill the tube with Calais sand and ram tight-
before bending. This process he has seen successfully performed
with the handle bars of cycles, the sand seeming to prevent the
tube from flattening at the curved parts. He does not know
whether it will answer for brass tubes, but the process has the.
merit of cheapness, and no doubt would be worth a trial.
[Reply to Spatula. — 91/13.]
Essence of Rennet. — Take a fresh rennet, and if there is a curd
of milk inside do not reject this, as it will contain much of the
ferment ; cut up the membrane small, and add tb it 50 ozs. of
distilled water and 2J ozs. of salt. Let stand together for six hours
in a wide-mouthed bottle in cool place, with occasional thorough
shaking. Then add 15 fluid ozs. of rectified spirit, and allow to
macerate for fourteen days with occasional shaking. Then strain
and filter. If it does not run bright at first tear up some filter
paper, and macerate the shreds in the cloudy liquid for twenty-
four hours. Then filter ; it will then run through bright. Most,
essences of rennet are not made sufficiently alcoholic. The rennet
ferment is not so easily precipitated by alcohol as is generally
supposed. [Reply to W. W. — 95/8.]
Dispensing Extract of Belladonna. — In the prescription
“potass, iodid., Jfi. ; ext. belladonna, 3i. ; saponis, §ii., m. ft. ung.,”
the sample you send marked not your own is made with soft soap,
not curd soap, and it naturally gives a more unctuous preparation
than yours, which is made with hard soap. So far, it is preferable
to yours. But on the other hand, you are right as to the bella¬
donna. The brown sample is made by using the alcoholic extract-
of the root ; although this gives a better Appearance than the
“green” extract of the fresh herb; you are right to use the latter,
since this, and this only, is “ ext. belladonnas.” It is taking an
unwarrantable liberty with the prescription to substitute “ext.
belladonnae alcoholic ” merely for the sake of appearances. This is-
carrying elegant pharmacy too far. [Reply to J. R. W. — 96/20.]
Apparatus for Analytical Work. — Balances. — For a cheap
balance you cannot do better than get one of Becker’s. Write to>
Messrs. Gallenkamp and Co., 2, 4, and 6, Cross Street, Finsbury.
The balance No. 1534 on their list is an excellent instrument, and
costs £7. Properly used this will last you a lifetime. A less
expensive but very good instrument is made by Verbeck, No. 1576
Gallenkamp’s list. This, to carry 50 grammes and turn to 0'5
milligramme, is £4 5s. with marked beam and rider. Their Students5-
Balance, No. 1628, is very good and quite accurate enough for
ordinary work, and is £2 9s. The first is recommended, as it will
always be useful to you in business. A good balance is like a
horse, if you treat it well it is as good when old as when new. —
Hot Water and Hot Air Ovens. — You will find all details of these,
in the list mentioned above. — Still for Distilled Water. — One of the-
best is Morris and Wethered’s Patent Still ; you will obtain full
particulars and prices for this on application to Messrs. Llewellins
and James, Bristol. Possibly the automatic still described and
figured by Maben ( Pliarm . Journ. [3], xviii., 881) would answer
your purpose. If not, you would find Remington’s a very good
form, but probably a home-made article would answer as well.
If you have it made of block tin by a tinsmith it will last for years.
[Reply to Countryman. — 96/35.]
OBITUARY.
Keyworth. — On May 27, George Alexander Key worth, Chemist,
and Druggist, Hastings. Aged 67. Mr. Keyworth was born at
Wantage in 1830, and commenced business as a chemist at 12,
Wellington Place, Hastings, in 1851. He took a deep interest in
all municipal affairs, and often gave his fellow-townspeople the
benefit of his advice through the medium of the press.
Starie.— On May 27. William Chantler Starie, Chemist and
Druggist. Aged 49.
Lambert. — On May 31. Thomas Lambert, Chemist and Drug¬
gist, Oldham. Aged 47.
COMMUNICATIONS, LETTERS, etc., have been received from
Messrs. Bates, Batly, Bayley, Bennion, Black, Bullivant, Butterworth, Collett,
Cruickshank, Cussons, Dodd, Durant, Durrant, Fletcher, Glyn -Jones, Harrison,
Henry, Hill, Hogg, Knight, Moss, Naylor, Riding, Rogers, Sawer, Sharman,
Sinclair, Stott, Strickland, U’Ren, Walker.
PHARMACEUTICAL JOURNAL.
505
INSECT POWDERS OF COMMERCE.
iS'CfeORGE REYNOLDS DURRANT.
jurr
r i JS7
the past quarter of a century at least twenty eminent
ch^f^ts^phan maeiste, aad microscopists have devoted some atten¬
tion to-kne/p^i}}^ i 4al qhai' ac ter i sti cs , chemical constituents, and toxic
properties of the ’Trisect powders of commerce. In the earlier part
of this period the references were exclusively to the powder from
the flowers of Chrysanthemum caucasicum or Persian variety, which
gradually gave way to the Dalmatian kind produced from the
flowers of the Chrysanthemum cinerariafolium, and it is possible that
the Dalmatian replaced the Persian variety because the latter was
the first kind to be grossly adulterated ; at least, it is true in my
experience that both kinds are equally useful if equally free from
sophistication.
A careful study of the whole of the literature of the subject is
more likely, in the absence of much personal experiment and
thought, to confuse the reader than to provide him with such
information as will enable him to distinguish the true powder from
sophistications, which are still as common, although changed in
character, as they have been at any time since the Persian powder
gave way to its honester rival. To anyone who has worked on this
subject for a few years the last paragraph may appear to be super¬
fluous, but it is evident that there is still a plentiful lack of
knowledge on the part of the majority of buyers, or it would be
impossible to account on any other hypothesis for the enormous
amount of grossly sophisticated insect powder which is sold as
genuine every season.*
The object I have had in view in recording the results of several
years’ attention to this subject is to provide a ready means of
quickly and cheaply ascertaining if a given sample of insect powder
is what it is represented to be by the seller, but before proceeding
to this part of the subject it will be profitable to briefly set forth
the results of the work of other investigators. These references
will not be by any means exhaustive of the subject, but will include
most of the literary notices which have come within my own
knowledge.
It will be found that the literature of the subject divides itself
into the following sections : —
(a) Toxic constituents.
(b) Microscopic appearance.
(c) Adulterations.
It is intended to keep to this division of the subject so far as may
be possible and convenient.
So far back as 1863, Hanaman Roch (‘National Dispensatory’)
attributed the insecticidal value of the powdered flowers of Chrys.
caucasicum to a volatile oil. Some years after, in the seventies,
Semenoff appeared to be practically in agreement with this state-
* While engaged in preparing this paper for the press, a curious confirmation
of my contention has been supplied by a correspondence with a provincial firm
of dealers in insect powder. I have no reason to doubt the bond Jules of the
firm, and must therefore conclude that such large sellers of insect powder as
they claim to be are yet profoundly ignorant of the characteristics of true insect
powder. I fear my charity is not sufficiently broad to give credit for good faith
in this firm’s opinion on the London trade in insect powder ! The following short
extracts are reproduced from this correspondence In reply to my request for
samples and quotations, “ Thank you for your enquiry, and are sending samples
of insect powder from closed flowers, 100s. per cwt., and from half-open flowers
at 75s. per cwt.” My reply to this quotation expressed regret at the misleading
description, as both samples were grossly adulterated, which drew a most in¬
dignant letter. “In reply to your letter, we think the party conducting the
analysis must have made some miscalculation, as we are direct importers from
Austria, and have, from the grinders there, the fullest assurance of its genuineness
and that the ‘ closed ’ and ‘ half-closed ’ are from flowers of that description and
from flowers only. We have sold the same article for seven years, and our sale
has greatly increased. As regards the London price for insect powder, the
import offered in London is second rate, both in quality and quantity, and
consists only of odd lots that have passed through several dealers’ hands. We
write strongly on this subject because we should not have been able to advance
our trade in this article to its present state if we had been capable of mis¬
description 1 ”
Vol. LVIII. (Fourth Series, Yol. IV.). No. 1407.
ment, but treated the matter more broadly, if less definitely, by
substituting “volatile substance” for the more definite, if less
accurate, “ volatile oil.” Immediately after (in 1876) Jousset de
Bellesme stated that, in his opinion, the active toxic principle was
a crystalline alkaloid. In 1877 this last statement was corrected
by R. Rother (Druggists’ Circular and Chem. Gazette) in a paper
giving the results of a very systematic and practical investigation,
the conclusions at which this writer arrived are as follow : — There
is no crystalline alkaloid ; there are (a) an oleo-resinous greenish-
yellow acid, “persicein”; ( h ) another acid body, “ persiretin,”
both inactive ; (c) active principle, a glucoside converted by boiling
into “ persiretin ” and glucose. These constituents are all soluble
in ether, alcohol, benzine, and petroleum ether, and insoluble in
chloroform. With the latter part of the statement, referring to
the solubility of all the constituents of any value in ether, etc., I
can cordially agree. Very shortly after the appearance of this
article by Rother a notice appeared in the Bulletin Soc. Chim. by
G. Dal Sie, in which he claims that the active toxic principle is to
be found in a volatile acid existing in the flowers in a free state.
M. Finzelberg (Pharm. Centralhalle, 1880) proved that a concen¬
trated tincture of the flowers had definite insecticidal properties,
and this statement has been confirmed by my own experiments on
flies. O. Tester (Pharm. Journ. [3], xii., 359) states that
the active principle is a soft resin. At the British Pharmaceutical
Conference, 1888, a paper was read by William Kirkby on the
microscopical characteristics of the flowers of C. caucasicum and
C. cineraricefolium. The paper was valuable so far as the subject
was treated, but it was less complete than the author intended,
inasmuch as sophistications were not taken into consideration.
Although the paper itself was thus limited in scope, the discussion
which followed covered the whole ground. Mr. Robinson expressed
his incredulity at the presence of any toxic agent, but this
bold sceptic was crushed by the President, assisted by Mr. Howie
and Mr. Martindale. In the Pharm. Zeitschr. fur Bussland, 1890,
E. Hirschsohn states that the active principle is neither a volatile
oil nor an acid resin; this statement is neutralised by F.
Schlagdenhauffen in an article in the Pharm. Zeitung, 1892, in which
he states that he found the toxic properties to be (a) yellow volatile
oil, and (h) uncrystallisable soft resinous mass (pyrethrotoxic acid
very soluble in ether. It seems to me that the average buyer of
insect powder, after careful consideration of the foregoing evidence
by so many able men, would remain more or less doubtful as to
the properties and characteristics for which he ought to look in
deciding upon the value of the various qualities to be found in the
insect powders of commerce. The results of my own work on this
part of the subject may be briefly stated as follows : —
The toxic properties are due to—
(a) A volatile oil amounting to 0-5 per cent, in picked specimens
of closed flowers and much less in open flowers.
(b) A soft acid resinous body, this is the principal source of
the toxic effect. It is found to the amount of 4-8 per cent, in
selected closed flowers, less than 4 per cent, in half-open flowers,
and still less in flowers that are fully open, the whole plant apart
from the flowers contains mere traces of resin.
The fine dry powder, after exhaustion with ether, has no decided
toxic properties, but numerous experiments on beetles convince
me that this exceedingly fine powder contributes something
to the insecticidal properties by its physical action, perhaps by
its effect on respiration reducing the vitality of the insect, and
also by impeding locomotion and preventing a speedy retreat from
noxious surroundings and a safe return to the customary lodgings.
The toxic properties of the volatile oil and resin may be proved by
isolating them and mixing them with an inert powder whose
506
PHARMACEUTICAL JOURNAL.
[June 12, 1897
physically deterrent equation has been ascertained by experiment
on beetles. I believe no vivisection licence is required for this.
Having referred to the toxic constituents of, and the propor¬
tions in which they exist in, genuine powder of the flowers of
C. cineraricefolium, it is very important to mention the fact that
chlorophyll, in its green unchanged form, is not found in selected
dried, closed insect flowers, as this fact has an important bearing
on one (and I think the most prevalent) form of sophistication to
be found in the present insect powders of commerce. I cannot
fully explain why it is that insect powder from half-open and from
flowers that are fully developed should show a certain amount of
chlorophyll colouring in the ether extract, but it may possibly be
that less care is taken in collection of these than is the case with
the more valuable closed flowers. But whatever may be the cause,
the fact remains that insect powder ground from selected closed
flowers is sensibly free from chlorophyll, whereas traces of it (less
than • 5 per cent. ) will be found in powders prepared from mixed
and half-open flowers, and in the foreign ground insect powders it
often amounts to from 50 to 80 per cent, of the total ether extract.
Samples have been recently examined by me yielding 6 per cent, of
ether extract, of which more than two-thirds was owing to
chlorophyll. It will therefore be seen that any estimate of the
value of insect powder based upon the percentage of ether extract
would be quite fallacious unless the chlorophyll be also determined
and deducted from the total. Microscopical examination is useful
in distinguishing the grosser forms of admixture, such as powdered
quassia and the woody tissue of the leaves and stems of the plant,
but this latter form of sophistication can be determined by the
method given further on. [For full particulars of the microscopical
appearance of true insect flowers, the reader is referred to the
paper by Mr. William Kirkby, F.R.M.S. (‘Proc. Brit. Pharm.
Conf.,’ 1888).]
Adulterants. — In using the term adulterants as applied to our
subject, it is intended to imply the presence in insect powder of
anything but the flowers of G. cineraricefolium. Adulterators of
insect powder have for their first object the cheapening of the
article sold, and occasionally they have a second object, i.e., to
improve its colour.
The first object has been achieved in the past by the addition
of powder of quassia, aloes, senna and Hungarian daisy, and the
artistic eye of the ignorant buyer has been satisfied by the addi¬
tion of the powder of fustic, turmeric and chrome -yellow. The
presence of quassia, fustic and turmeric may be detected by the
aid of the microscope, and chrome-yellow (salt of lead) chemically.
The presence of the powder of Hungarian daisy is more difficult
to detect microscopically, but it yields 10 per cent, of ash, whereas
true insect powder yields but 6 ‘5 per cent. On this point the
reader is referred to an extract from a paper by J. Schrenk
(American Journal of Pharmacy, 1889) in the ‘ Year Book,’ 1890.
It is hoped that it will not be difficult to accept my contention
that by the term insect powder it is intended by both buyers and
sellers that powder of the flowers of the G. cineraricefolium is
understood, at least so far as transactions in the open market are
concerned. Owners of proprietary insect powders have a right to
compound them as they please, and this right has been freely exer¬
cised by the use of powdered quassia, colocynth, etc., as well as
by the addition of various colouring agents. Although powdered
quassia mixed with powdered insect flowers must be considered to
fall under our definition of adulteration, it is quite possible that a
small proportion is useful in insect powder, increasing or broadening
the base of its usefulness. The same remarks apply to other
admixtures, such as powdered bitter apple, and the only criticism
to be made on this point is that if powdered quassia or other
powders having insecticidal properties be added to insect powder,
let it be done with the knowledge of buyers and at the proper price.
The adulterants j ust referred to are for the most part things of
the past, with the exception of added colouring matters, which
are still very commonly used to meet the too general want of know¬
ledge of the proper appearance of true insect powder. At the
present time the insect powders of commerce may be divided into
the following classes
1. Ground from closed, (a) wild, or ( b ) cultivated flowers of
C. cineraricefolium.
2. Ground from half open or mixed half open and open flowers.
3. Ground from damaged flowers.
4. Foreign ground, divided into grades of badness under the
meaningless terms : “Closed flowers,” “half open flowers,” etc.,
etc. Of these sorts there appears to be as many as there are of
hen’s eggs, which embrace all the kinds between “new laid” at
the top of the list, and “ political” at the bottom. The English-
ground insect powders do not always justify the description given,
but, in my experience, the foreign -ground specimens never do, and
it is with much satisfaction that it is noted that a ready method of
distinguishing “ foreign ground ” is to hand.
It will be seen from the remarks made on the toxic constituents
of the flowers of G. cineraricefolium that the following statement
embraces the results of my own experience as well as that of the
majority of labourers in the same field : —
That the value of insect powder is in direct proportion to the
combined amount of essential oil and soft acid resin, and in inverse
proportion to the amount of chlorophyll — both statements to be
read together.
It has not been my good fortune up to the time of writing this
to have met with one sample of “ foreign-ground” insect powder
that was not grossly sophisticated.
A perfect sample of insect powder should pass a sieve having at
least eighty meshes to the linear inch ; the particles would be,
therefore, approximately 1/160 of an inch in greatest magnitude.
(The powder has been passed through a sieve with 100 meshes to
the linear inch, but 90 is the more usual number. ) The powder
should yield 5 ‘25 per cent, of combined essential oil and soft resin ;
chlorophyll should be absent or present in the merest trace.
The following simple method of testing the value of insect
powder should be adopted by all chemists who wish to sell a
genuine powder, or, to put the matter on lower grounds, who wish
to increase their sale of this really important commercial product.
Place 100 grains of the powder to be tested in the cylinder of a
glass syringe (1 oz.). The powder should be pressed down com¬
pactly on to a piece of absorbent cotton, to act as a filter. Moisten
with ether ’735. Close the top of the syringe, and macerate for 30
minutes ; percolation may then proceed ; the powder being reper¬
colated with the same fluid four times, and finally washed through
with sufficient ether to make up one fluid ounce. The resulting
percolate should be of a rich yellow colour, if a pronounced
green colour be the result the sample may be discarded at once.
In the absence of much green colouring matter, the fluid may
be carefully evaporated (temperature not exceeding 200° F.), and
the residue weighed in a tared watch-glass. The resulting soft
mass should not weigh less than 3 '75 grains, and in the finest
samples reaches 5 '5 grains, and should have the pleasant and
characteristic odour of the flowers.* At the present time the price
* Exactness may require the determination of the chlorophyll. If an appreciable
amount be present this may be done by boiling the residue in dilute sulphuric
acid and volumetrieally determining the converted chlorophyll as glucose with a
suitable copper solution. For my own purposes I should unhesitatingly reject
the sample rather than take this unnecessary trouble, unless a fee were attached
to the operation.
June 12, 1897]
PHARMACEUTICAL JOURNAL
50 7
of insect powder varies between 8 d. and 2 s. 2d. per lb., the
highest price representing the value of English ground powder
from closed flowers and the lowest powder “ foreign ground ” from
the whole plant. This ground whole plant appears to be the prin¬
cipal sophistication, apart from colouring matter, found in
commerce at the present time.
I desire to acknowledge my indebtedness to Mr. Charles Umney
for very fine specimens of the dry flowers of G. cineraricefolium.
HOW TO CUT SECTIONS OF CAPSICUM FRUITS.
BY ABRAHAM FLATTERS.
The method of using the microtome having been described (ante,
p. 485), the preparation and cutting of dried specimens will now
receive attention, capsicum fruits being taken for the purpose.
The parts of these fruits, as obtained from the shop of the chemist,
are naturally very much disorganised, and but a vague idea can
be gained at the best of the structural parts 'by the examination
of the very best section obtainable from such a source. The pre¬
paration of the capsicum for cutting should be effected in the fol¬
lowing manner : Select the best-looking and most complete fruits
for the purpose, place them in water for twelve hours to relax, and
do the same with some of the seeds which have been removed
from the fruits.
When properly relaxed, pass the specimens through spirit of
varying strength, commencing with 25 to 50 per cent., and subse¬
quently treating in turn with 70 and 92 per cent, alcohol, allowing
them to stand for two to three hours after each change. They
will now be ready for imbedding in the microtome.
Imbedding in Celloidin.
1. Pour off the spirit, cover with absolute alcohol, and allow
to stand for twenty-four hours.
2. Pour off the alcohol, cover with pure ether, sp. gr. 0'720,
and allow to stand for twelve hours.
3. Pour off the ether, cover the specimens with equal parts of
absolute alcohol and ether, and add a sufficiency of celloidin chips
(Schering). Allow to stand for several hours, or until the celloidin
is thoroughly dissolved and the parts are permeated. The opera¬
tion should be repeated day after day until a concentrated celloidin
mass is obtained. By this means the fruit will have become
thoroughly permeated, and may now be lifted out of the mass with
forceps and dropped into chloroform, sp. gr. 1 '497.
4. Allow to remain in the chloroform until the celloidin is
coagulated. This will be indicated by the specimen sinking to the
bottom of the bottle.
5. Remove the specimen into 92 per cent, alcohol, in which it
can be permanently preserved.
Section Cutting.
The imbedded fruit should be trimmed ready for sectionising
by removing any projecting parts of the celloidin. It may now be
placed in the well of the microtome on its “ basal end,” melted
paraffin is poured into the well, and when this is set hard the
sections can be cut.
For the preparation of longitudinal sections a hard cork carrier
should be placed in the well of the microtome, and the fruit
arranged on this in such a manner that median sections can be
cut. This is effected by sticking two or three pins into the cork
to hold the specimen in position until the paraffin surrounding it
is set hard ; the pins can then be drawn out and the desired
sections cut. This method also applies to the imbedding of a
single seed.
After the sections are cut they should be placed in 92 per cent,
alcohol, stained with carmine, the celloidinised ones cleared with
oil of bergamot, the non-celloidinised ones with oil of cloves, and
then mounted in Canada balsam.
BOTANIC GARDENS OF THE WORLD.
VII.— KEW GARDENS (Continued).
The appointment of Sir W. Hooker, then Professor of Botany at
the University of Glasgow, as Director of the Royal Gardens at
Kew, resulted in a sweeping and much-needed reform. From 1841,
the year of his appointment, till 1859, when he presented an elabo¬
rate survey to Parliament of the changes and improvements made
there under his direction, his aim was to make of the Royal
Gardens “a complete national establishment.” He had to
remember that Government in taking them over aimed at two
distinct things : the healthful recreation of the public, “gratifying
the national love of gardening, and affording much popular
information as to the appearance, names, uses, and native
countries, etc., of an extensive series of useful and ornamental
plants from all lands and climates, together with their products,
whether as food, drugs, dyes, timbers, textiles, or cabinet work,”
and the encouragement of horticulture and scientific botany,
“ promoting the useful arts which depend on vegetable produce,
supplying information to botanists, and aiding their publications,
and imparting a knowledge of plants to travellers, merchants, and
manufacturers, also by training plant collectors and gardeners for
home, colonial, and foreign service.”
The Botanic Gardens transferred to the nation in 1841 consisted
only of eleven acres, but by successive additions they reached in
1847 a total of seventy-five acres. In 1846 there was also placed
under the direction of Hooker the Pleasure Gardens or Arboretum,
consisting of 250 acres, separated by a wire fence from the
Botanic Gardens and opening into them by four gates. The old
Arboretum, consisting of five acres planted by Aifcon, and situated
in the northern part of the Botanic Gardens, was described by
Hooker in 1847 as “ a small piece of ground .... but crowded
with hardy trees and shrubs of extreme interest and value.” Near
the Temple of the Sun were noble trees of the Turkey oak, the
oriental plane, a good cedar of Lebanon, a very large locust tree,
a lotus of North America, a fragrant sassafras, and a healthy,
though young, cork tree. Along the walk by the east end of the
orangery were American limes, oaks, hickories, red and yellow-
flowered horse chestnuts. In the other direction were many other
interesting trees, Napoleon’s willow, the paper birch, many rare
pines, the manna ash, and Glastonbury thorn. Hooker aimed at
obtaining in the pleasure grounds an Arboretum that should contain
every tree and shrub capable of withstanding the open air in this
climate. In 1859 it contained a classified collection of 3500 hardy
trees and shrubs, which he was able to describe in his report as
being mostly in a thriving condition. Of the two nurseries placed
by him in the Arboretum, one was specially intended for planting
the grounds at Kew with ornamental trees and shrubs, and rearing
a stock for exchange. The other was formed in 1855 at the
desire of the First Commissioner for Supplying the Metropolitan
Parks. “ In 1856 it furnished 1010 trees (chiefly planes and elms);
in part 1857, 4100 trees : and in 1858, 2475, the sizes varying from
6 to 14 feet : while our own Pleasure Ground Arboretum sent to the
parks of the metropolis, with the sanction of the Board, in 1857,
9289, and in 1858, 2814; trees and shrubs of great variety, besides
furnishing the grounds at Kew with no fewer than 18,000 in the
year just closed” (1859). A lake was also formed under Hooker’s
directions, and the Queen’s Garden, a beautiful piece of ground
reserved for the use of Her Majesty, and situated at the S.W.
corner of the pleasure grounds, was enlarged by fourteen acres
being taken from the Royal Deer Park, new walks were cut through
it, and much old decayed wood and copse cleared away.
508
PHARMACEUTICAL JOURNAL.
[June 12, 1897
In 1841 there were only 9174 visitors to the Gardens. In 1858
there were 405,376 exclusive of those to the Herbarium and
Library. In 1856 the commissioners to make the Gardens more
attractive to the public obtained an increased grant for keeping
them up. More flower beds were designed, new shrubberies and
walks were formed, clumps and standard trees and flowering shrubs
were planted with a view to effect.
Shortly after the appointment of Hooker as Director at Kew,
the subject of a new Palm House was brought forward, and the
present Palm House was completed in 1848. For several years the
palms stood on the floor of the house, but in 1854 a part of this
perforated iron floor was removed, and three beds, each 8 feet wide,
were made on each side of the centre passage of the house with 4
feet passages between them. The large palms were planted in the
centre area of the palm house, and the others grown in round and
square plant boxes, and pots of various sizes, the smaller ones
being placed on side shelves. With few exceptions they were
carefully labelled, the labels being conspicuously placed so as to be
readily seen by the public. In his * Guide to Kew Gardens,’
published in 1853, Sir W. Hooker directs especial attention to the
date, cocoa-nut, oil-nut and cabbage palms, the ivory-nut and sago
palms, the chocolate-nut, tamarind, mango, breadfruit, and
cinnamon.
In his report for 1854 he says “The palm house stove was
never more beautiful than at the present moment, and so rapid
has been the growth of some of the trees and shrubs that we have
been obliged to move them from their high tubs and sink them in
the ground.” In 1856 a journalist wrote of this house and its
contents : “ On entering the magnificent building the visitor
suddenly finds himself in the midst of a tropical vegetation.
Broad leaved plantains, bananas, stoeleitzias and uranias, feathery
bamboos, tree ferns, and tamarind trees. Spiny screw pines and
cacti are mingled with numerous palms of all dimensions and sizes,
the whole being gracefully interwoven and surrounded by creeping
and winding plants, passion flowers, bauhinias, jasmines,
aristolochias and others, and agreeably relieved by the vivid green
of densely crowded lycopodiums, covering the turf, the ground
between them.”
When Sir W. Hooker took the directorship the collection of succu¬
lents ‘ made chiefly by Masson and Bowie 5 was housed in a low lean-
to stove, 40 feet long, fitted up with shelf staging in two directions,
one for euphorbias and cacti, the other for mesembranthemums,
crassulas, sempervivums, small species of aloes, gasterias, etc
The collection increased by gifts and purchases, especially in cacti)
agaves, and other allied species and plants from Mexico. In 1854
a new house was erected for its accommodation, 200 feet long and
30 feet wide, having a span roof facing east and west 15 feet high-
Climbers were planted in a shallow trough, two feet wide, filled
with soil and supported with brick arches, and were trained up
the rafters, flowering freely. This trough occupied the sides and
ends of the house, and its surface was covered with sand or graveb
on which the pots containing the low growing plants were ar¬
ranged according to their families. On the centre of the house>
■vVhich was level, were arranged the taller plants in pots. It was
heated by hot water pipes. Of this house Sir William Hooker says
in his Parliamentary report for 1855 : “ The erection during the
year of a new house for succulent plants, 200 feet long, 30 feet
wide, and 15 feet high, has enabled us to display — and to advan¬
tage for the first time — our noble collection of medicinal aloes and
euphorbias, grotesque cacti, and fibre-bearing agaves ; this is
perfectly unique of its kind.”
In 1856 Mr. John Smith, the Curator of the Kew Botanic Gar¬
dens, drew up a list of the succulent collection, which was printed
for the purpose of making exchanges with other gardens, and this
he brought up to date in 1864.
In 1844 it became necessary to find further accommodation for
orchids, which through purchases, exchanges, and presentations
had greatly increased in number. A lean-to house, 60 feet long
and 17 feet wide, was doubled so as to make a span-roofed house
14 feet high. The centre was filled with a staging of slate shelves
facing north and south with a passage in the centre, and passages
and stone shelves on both sides and ends. The roof was glazed
with thick sheet glass in squares 4 feet in length. The house was
thus well fitted and heated, but the large area, dry stone paths,
smooth slate shelves, and large squares of thick sheet glass were
ill adapted to keep tropical orchids in a healthy condition. They
did not thrive, and after a trial of two years it was found
necessary to remove them to two of the old fruit houses which had
been remodelled and heated by hot water. The tropical species
were placed in what had been a peach house 80 feet in length,
while the temperate species occupied a low pine stove 40 feet in
length. About 1858 Hooker secured a special orchid cultivator
for the Kew collection, and was able to report in 1859 that the
orchideous plants were improving rapidly under his care.
In 1847 the herbaceous and grass collections were transferred to
new quarters, formed by the addition to the Botanic Gardens of
the Royal Kitchen and Forcing Gardens. Three acres thus
acquired were laid out in beds of various sizes to suit the number
of species in the different genera of the system of Jussieu. In
1853 the foreman, James Niven, drew up a catalogue of these
plants, a considerable number of copies of which were printed at
the expense of the Garden for distribution, in order to help in
making exchanges with other gardens. This catalogue consisted
of sixty-two pages, and enumerates 5414 species arranged under
their natural orders, including Graminece, the number of which
then amounted to 359. Two collections much appreciated by
students were a separate collection of British plants commenced in
1843, and a collection of hardy medical plants, contiguous to the
British collection made on the acquisition of the ground called the
Paddock in 1853.
Another small but interesting collection was made in 1844, on
the formation of the broad walk which runs from the Orangery,
afterwards the No. 3 Museum, to the pond. Oblong clumps of
rhododendrons were planted on each side, and in front of them a
series of round and oblong beds was formed. These were exclu¬
sively occupied by low growing species of Ericaceae, each species
occupying a bed. They grew well and flowered freely, but were
removed in 1855 to make way for carpet bedding.
(To be continued.)
Chrysoidin and Cholera. — Blachstein states that chrysoidin
precipitates cholera bacilli from a suspension of these microbes.
Two interesting facts are connected with this flocculent precipi¬
tation, namely (1), that the same peculiarity belongs to the serum
of those immune against cholera ; and (2) that no other body except
chrysoidin is known to possess this property. The nearest relative
of chrysoidin (vesuvin) and over fifty azo bodies investigated by
the author have no such action. It not only acts as a precipitant,
but also as a disinfectant for cholera, being in this respect more
active than phenol. It is not poisonous. A solution of 1 in 1000
may be taken in teaspoonful doses without harm. It might be
used with advantage for disinfecting water. It does not appear to
act as a curative agent when taken internally, but is a good pro¬
phylactic. Animals inoculated with cholera bouillon- containing
chrysoidin continued to live, while the same bouillon without the
dye caused infection. — B. M. J. Ep., 1/97/28.
June 12, 1897]
PHARMACEUTICAL JOURNAL.
509
REAGENTS, REACTIONS, METHODS AND FORMULAS,
KNOWN BY THE NAMES OF THEIR AUTHORS.*
( Continued from page 4-93. )
Bela Haller’s macerating mixture. Glacial acetic acid, 1 part ;
glycerin 1 ; water 2. Cells of the central nervous system of
mollusca show less shrinkage with this mixture after maceration
for 30 to 40 minutes than with other liquids.
Bellonci’s neurological method. Treat the material with 0’5
to 1 per cent, osmic acid solution, hardening for 14 to 24 hours only,
and after cutting sections treat them for 3 or 4 hours with 80 per
cent, alcohol, and then with ammonia.
Benda’s copper htematoxylin. Harden the material with
chromic acid or Flemming’s solution and leave sections for 24
hours in a 5 per cent, solution of neutral copper acetate at a tem¬
perature of about 40° C. , wash out well with distilled water, and
stain to a dark grey or blackish tint in a saturated aqueous hema¬
toxylin solution. Decolorise the sections in 0'2 per cent, hydro¬
chloric acid until light yellow, put back into the copper solution
until they turn bluish grey, then wash, dehydrate, clear, and
mount in balsam.
Benda’s double stain. Sections are stained for 24 hours in
aniline water safranine solution, then for about half a minute in
a solution of 0'5 gm. Lichtgriin, F.S., or Saureviolett (Griibler) in
200 C.c. of alcohol. After dehydration mount in balsam.
Benda’s iron hsematoxylin. Sections are mordanted for 24
hours in following solution, diluted with 1 or 2 parts of water
Ferrous sulphate, 80 parts ; water, 40 ; sulphuric acid, 15 ; nitric
acid, 18. Well wash and place in 1 per cent, aqueous hfematoxylin
solution until quite black. Again wash and differentiate in 30 per
cent, acetic acid.
Bergonzini’s staining method for plasma cells. Mix 1 volume
of Saurefuchsine solution (0-2 per cent.) with 2 volumes of methyl
green solution (0'2 per cent.) and 2 of gold orange solution (0-2 per
cent.), and filter the mixture through cotton wool. The gold
orange used must not precipitate methyl green. Sections are
taken from alcohol or corrosive sublimate solution, washed with
water, and stained for 3 to 4 minutes. They are then washed with
water for 1 or 2 minutes, immersed in absolute alcohol for 2
minutes, cleared in bergamot oil or creosote, washed in turpentine,
and mounted in balsam.
Berkley’s modification of Weigert’s staining method. Harden
slices of tissue, not exceeding 2 ’5 Mm. thick, for 24 to
30 hours in Flemming’s solution, at a temperature of 25° C.
Then place in absolute alcohol, which should be changed twice
during the first 24 hours, and when sufficiently hardened
imbed in celloidin and cut. Wash sections in water, leave them
overnight in a saturated solution of copper acetate (or warm there¬
in at 35° to 40° C. for half an hour), then wash and stain for 15
to 20 minutes in a solution made by adding 2 C.c. of lithium
carbonate solution (saturated) to 5 C.c. of boiling water, boiling
for 2 minutes, and then adding 1'5 to 2 C.c. of 10 per cent,
hsematoxylin solution. The stain should be warmed to 40° C., and
after the sections are cooled they must be differentiated for 1 to
3 minutes in Weigert’s ferricyanide liquid, diluted, if neces¬
sary, with one-third of water. Subsequently treat, in the order
mentioned, with water, alcohol, and bergamot oil, and finally
mount in xylol balsam.
Berlinerblaus’ method of regenerating Weigert’s hsematoxylin.
Add 2 '5 to 5 per cent, of baryta water to the used solution, shake
well and leave for 24 hours. Then pass carbon dioxide
through the solution, again allow to stand for 24 hours, and
filter.
Bertlielot’s alcohol reaction. If a dilute solution of alcohol is
shaken with a few drops of benzoyl chloride and soda solution until
the odour of benzoyl chloride disappears, the peculiar odour of
ethyl benzoate becomes apparent.
Berzelius’ test for albumin. Meta phosphoric acid in freshly
prepared concentrated solution precipitates all albuminous sub¬
stances (except peptone) from their aqueous solutions.
Betke’s methylene blue method. After staining tissues of Ver¬
tebrates and rinsing in salt solution, place them for 2 to 5
hours, according to size, in a solution consisting of ammonium
molybdate, 1 Gm. ; water, 10 Gm. ; hydrogen peroxide, 1 Gm.
(For Invertebrates use ammonium molybdate, 1 Gm. ; water,
10 C.c. ; hydrogen peroxide, 0-5 C.c.) This should be not more
* After Schneider, Altschul, Lee, Squire, Crookshank, and others.
than 8 days old, and is best cooled to 0° C. Subsequently
wash in water for 0'5 to 2 hours, dehydrate in alcohol at 0° C.,
clear in clove oil or xylol, and imbed in paraffin of celloidin in
the usual way.
Bethe’s stain for chitin. Place series of mounted sections on
slides in a freshly prepared 10 per cent, solution of aniline hydro¬
chloride, containing 1 drop of hydrochloric acid for each 10 C.c.,
for 3 or 4 minutes, then rinse in water, and put the slide with sec¬
tions downwards in a 10 per cent, solution of potassium bichro¬
mate. The process may be repeated if the stain is not sufficient!}'
intense, but the sections must be well rinsed with water after each
immersion.
Bettendorf’s test for arsenic. A solution of stannous chloride
in concentrated hydrochloric acid, sp. gr. 1T9, when heated with
a solution of arsenic or arsenious acids in strong hydrochloric acid,
yields a brownish turbidity or precipitate of metallic arsenic and
tin. The presence of much sulphuric acid, or of oxidising or organic
substances, interfere with the reaction.
Bianco’s chromo-acetic acid. Add to concentrated acetic acid
one-tenth its bulk of a 1 per cent, chromic acid solution.
Bianco’s narcotising mixture for Actiniae, etc. Glycerin,
20 parts; alcohol (70 per cent. ), 40 parts; sea water, 40 parts.
Pour carefully on to the surface of the water containing the
animals, and allow it to diffuse quietly through it. Several hours
may be necessary for this.
Bickfalri’s digestion fluid. Dried stomach mucus, 1 Gm., is
mixed with 20 C.c. of hydrochloric acid (0‘5 per cent.), and put
into an incubator for 3 or 4 hours, then filtered. Macerate tissue
in this for 0'5 to 1 hour.
Bieber’s reagent consists of equal parts of concentrated sul¬
phuric acid, red nitric acid, and water.
Biel’s cocaine test. If a solution of 0T Gm. cocaine salt in 1
C. c. concentrated sulphuric acid is heated for several minutes on a
water bath, the addition of several cubic centimetres of water
causes the formation of a white crystalline precipitate of benzoic
acid.
Biltz’ test for sodium mono- and bi-carbonate. When treated
with mercuric chloride under certain conditions, these salts yield a
white or brown precipitate respectively.
Biondi’s staining mixture. See Ehrlich-Biondi’s mixture.
BischofPs reaction for gallic acid. When heated with dilute
sulphuric acid and cane sugar, gallic acid produces a red colora¬
tion. See also Pettenkofer, Strassburg.
Bisch.off’s melting-point test for butter. See Drouot’s test.
Bizzozero’s gentian -violet method. Stain in Ehrlich’s gentian-
violet solution for 5 or 10 minutes or longer, then wash in alcohol
for 5 seconds, in Gram’s iodine solution for 2 minutes ; alcohol for 20
seconds; aqueous chromic acid solution (0T per cent.) for 30
seconds ; alcohol for 15 seconds ; chromic acid again for 30 seconds,
and alcohol for 30 seconds. Afterwards treat with changes of clove
oil until final decoloration, and mount in dammar. In another
process by Bizzozero the treatment with iodine solution is omitted.
Bjeloussow’s gum arabic injection mass. Mix a syrupy solu¬
tion of gum arabic and a saturated aqueous solution of borax, so
as to have in the mixture 1 part of borax to 2 parts of gum. Add
distilled water gradually to the resulting mass, rubbing it up
meanwhile, and then force it through a fine-grained cloth,
repeating the operations until a mass free from suspended gela¬
tinous clots is obtained.
Blum’s hardening solution. Formalin diluted with 10 volumes
of water.
Boas’ reagent. This is a solution of tropseolin, or paper satu¬
rated with such solution.
Boccardi’s solution. Oxalic acid solution (0T to 0-3 per cent.)
or formic acid, 5 C.c. ; oxalic acid solution (1 per cent.), 1 C.c. ;
water, 25 C.c.
Bodde’s reaction for distinguishing between resorcin and
phenol, benzoic acid, and salicylic acid. A solution of resorcin
yields a violet colour with sodium hypochlorite, which fades to-
yellow ; with more hypochlorite solution and heat a yellowish-red
or brown colour is produced. If before the addition of the hypo¬
chlorite ammonia is added, a violet colour is first produced, which
changes to yellow and upon heating is converted into dark green.
Phenol, salicylic acid, and benzoic acid yield a slight colour with
hypochlorite only upon heating. Upon previous addition of am¬
monia the acids are not coloured.
Boedecker’s test for albumin. If potassium ferrocyanide is
added to a solution containing albumin (e.g., urine), which is
510
PHARMACEUTICAL JOURNAL.
[June 12, 1897
acidulated with acetic acid, turbidity or a flocculent precipitate is
produced.
Boehmer’s hematoxylin. Dissolve (a) crystallised hematoxylin,
1 Gm., in absolute alcohol, 10 C.c., and (6) ammonia alum, 10 Gm.,
in distilled water, 200 C.c. Mix the two solutions and allow to
ripen for some days before use. Filter after standing a week.
Wash out with aqueous solution of alum (05 per cent.) or with
acids.
Boernstein’s test for saccharin. The substance to be tested is
extracted with ether, and the extract, after the ether has been
removed by distillation, is heated with resorcin and sulphuric
acid. An excess of soda solution is then added, and if saccharin
is present, a strong fluorescence is produced. According to
Hooker, other substances, e.g., succinic acid, also produce this
reaction.
Boettger’s (also Boettcher’s) test for glucose. A dilute solution
of glucose (or diabetic urine) is heated with a solution of sodium
carbonate and some bismuth subnitrate or bismuth oxyhydrate.
If reduction takes place, the suspended bismuth compound is
blackened. According to Krueger, a stable reagent can be pre¬
pared by heating 15 Gm. bismuth nitrate, 15 Gm. tartaric acid,
75 Gm. water, sufficient aqueous potash solution to effect solution,
and some glycerin.
Boettger’s test for the red colour of wine consists in the addition
of 1 volume of concentrated copper sulphate solution to 3 volumes
of wine diluted to ten times its volume. Pure red vTine becomes
discoloured. Unfermented wine, fuchsine, and the colouring
matter of bilberry, malva, and cherries remain unchanged or
assume a violet colour.
Eoettger’s reagent for ozone. Filter paper saturated with
solution of gold chloride free from acid is coloured violet by ozone.
A test paper formerly suggested by Boettger contained thallium
hydroxide, which was coloured brown by ozone.
Boettger’s test for sugar in glycerin. Five drops of glycerin
is heated to boiling with 100 drops of water, 1 drop of nitric acid,
sp. gr. 1 '3, and 0‘03 to 0-04 Gm. ammonium molybdate. If sugar
is present, the solution is coloured intensely blue.
Boettger’s reagent for hydrogen peroxide. On adding to a
solution containing hydrogen peroxide a solution of starch, with
cadmium iodide, and a little ferrous sulphate, the blue colour of
starch iodide is produced. This is also known as Schoenbein’s
reagent.
Bohlig’s reagent for ammonia. 1. Dissolve mercuric chloride,
1 part in water 30. II. Dissolve potassium carbonate 1 in water
50. Ammonia whether free or combined with carbonic acid
produces a w hite turbidity with solution I. If this reaction is
first brought about upon the addition of solution II., the ammonia
is combined with other acids.
Bonastre’s reaction for myrrh. Strips of filter-paper are
saturated with tincture of myrrh, dried, and moistened writh a
drop of nitric acid. If the tincture be made from genuine myrrh
a violet colour will be produced.
Born and Wieger’s quince mucilage. To two volumes of
quince mucilage add one volume of glycerin and a trace of carbolic
acid. This preparation is used to fix serial sections to slides, a
gentle heat being applied for that purpose.
Borntraeger’s reaction for aloes. An alcoholic extract of
aloes is shaken with benzin, and the benzin solution, after separa¬
tion from the alcoholic layer and the addition of a trace of strong
ammonia water, is slightly heated while shaken. Aloes, like
rhubarb, turmeric, galls and catechu produces a violet coloration
of the ammoniacal solution.
Bouchardat’s reagent for alkaloids. Dissolve, iodine 10 Gm.,
in potassium iodide, 20 Gm., in water, 500 Gm. This reagent
produces reddish-brown precipitates with aqueous solutions of
most alkaloids.
Boudard’s test to distinguish between fatty oils. The oils
are mixed with nitric acid, sp. gr. 1 -45 to 1 50. In the case of
genuine cod-liver oil a carmine-red coloration is gradually
produced.
Boudet’s reagent for fatty oils is fuming nitric acid. Olive oil
becomes solidified upon the addition of 5 per cent, of the acid.
See Barbot.
Brand’s reaction for quinine and quinidine. Salts of these
alkaloids after trituration with a little chlorine water, are coloured
green upon the addition of ammonia (thalleioquin reaction).
If ammonia water be added drop by drop to the solution of the
alkaloids, after the addition of a slight excess of chlorine water,
a green flocculent precipitate is produced which dissolves in an
excess of the ammonia water to form a green solution.
Brand’s reaction for fluorine in beer is a modification of Nivier’s
test, which see. The fluorine in the precipitate is converted into
hydrogen fluoride by means of sulphuric acid, and the former acid is
then identified by means of its etching properties.
Brady’s chloral hydrate medium. A 2'5 per cent, solution of
chloral hydrate in water.
Braeutigam-Edelmann’s test for horse meat. Boil 50 Gm.
of the meat with 200 Gm. of water for one hour, and the filtered
extract is evaporated to one-half its volume. After the albumin
has been removed by means of dilute nitric acid, iodine water is
added so as to form a layer. Horse meat, on account of the large
percentage of glycogen it contains, produces a burgundy-red zone.
Starch and dextrin interfere with the reaction, the former pro¬
ducing a blue, the latter a red colour.
Brandt’s glycerin gelly. Soak 2 parts of gelatin in water till
soft, then drain, melt, add 3 parts of glycerin, and filter.
Brass’ alcoholic carmine. Take 100 C.c. of 70 per cent, alcohol,
15 drops of hydrochloric acid, and an excess of carmine.
Braun’s test for glucose. On heating a solution of glucose with
a few drops of a solution of picric acid (1 : 20) a deep red colora¬
tion is produced.
Braun’s nitric acid reaction. Upon the adding to a solution of
a nitrate (or of free nitric acid) a small quantity of aniline sul¬
phate and subsequently of concentrated sulphuric acid a violet-blue
coloration results.
Bristol’s method of regenerating osmic acid solutions. Add 10
to 20 drops of fresh hydrogen peroxide solution to each 100 C.c. of
1 per cent, osmic acid.
Brouardel and Boutmy’s test to distinguish between pto¬
maines and plant alkaloids. I. With potassium ferricyanide and
ferric chloride ptomaines produce a blue colour. II. Write on
silver bromide paper with a quill and solution of the alkaloid or
ptomaine. After the paper has been laid aside for half an hour,
protected against the light, develop with hyposulphite. In the
case of ptomaines the writing appears black, but this is not so in
the case of plant alkaloids. Morphine also yields reaction I. (comp.
Kieffer’s reaction, in fact none of the reactions based on reducing
properties can be regarded as characteristic).
Bruecke’s digestion fluid. Glycerinated extract of pig’s stomach,
1 volume ; hydrochloric acid (0'2 per cent.), 3 volumes ; thymol, a
few crystals.
Bruecke’s reaction for the colouring matter of bile. See
Gmelin’s reaction.
Bruecke’s biuret reaction for albuminous substances. Coagu¬
lated albumin takes a fine violet colour when treated first with
dilute copper sulphate solution, and after removal of the excess
of that reagent with dilute soda solution. Compare Rose’s biuret
reaction.
Bruecke’s reagent for glucose. Boil 55 Gm. of freshly-
precipitated moist bismuth subnitrate with a solution of 30 Gm.
potassium iodide in 100 Gm. of water for 10 minutes. Then add
5 Gm. of 25 per cent, hydrochloric acid. Glucose (diabetic urine)
effects reduction with formation of a brown or black coloration.
Brulle’s test for foreign oils (cottonseed oil) in olive oil. 10 C.c.
of the oil is boiled withO'l Gm. of powdered albumin and 20 C.c. of
nitric acid. When all the albumin is dissolved the genuine oil
remains almost colourless, and upon cooling it becomes turbid and
straw-yellow. The colour remains the same after standing 24
hours, and the liquid then solidifies. In the presence of cotton¬
seed oil the liquid becomes orange to brownish-red upon solution
of the albumin, and as a rule no solidification takes place.
Brunner’s reaction for glucosides. Upon heating with bile and
sulphuric acid a red colour is produced (reversed Pettenkofer’s
reaction).
Brun’s glucose medium. Mix distilled water, 140 parts j
glucose, 40 parts ; and glycerin, 10 parts ; then add camphorated
spirit, 10 parts, and filter to remove excess of camphor.
Brunotti’s gelatin imbedding mass. Dissolve 20 Gm. of gelatin
with heat in 200 C.c. of distilled water, and add 30 to 40 C.c. of
acetic acid with 1 Gm. mercuric chloride after filtering.
Buckingham’s reagent for alkaloids. A freshly prepared
solution of ammonium molybdate, 1 Gm., in concentrated pure
sulphuric acid, 16 Gm. Heat is applied until the solution is clear.
The reagent yields precipitates of different colour with various
alkaloids. Comp. Hager, ‘ Pharm. Praxis,’ 1 , 209.
Bunge’s method of staining flagella. Use as a mordant a
mixture of 3 parts of aqueous solution of tannin with 1 part of
June 12, 1897J
PHARMACEUTICAL JOURNAL*
511
aqueous solution (1 in 20) of ferric chloride, adding 1 C.c. of
saturated aqueous solution of fuchsine to each 10 C.c. of the
mixture. Treat preparations with this mordant for five minutes,
then wash and stain with Neelsen’s solution.
Butschli’s imbedding method. Pass directly from chloroform
into a solution of paraffin in chloroform, and afterwards evaporate
off the chloroform at the melting-point of the paraffin.
Butschli’s iron hematoxylin. Treat sections with a weak
brown aqueous solution of ferric acetate, wash with water, and
stain in 0‘5 per cent, solution of hematoxylin in water,
( To be continued. )
SIXTY YEARS’ PROGRESS IN CHEMISTRY AND THE
CHEMICAL ARTS.*
BY PROFESSOR THORPE, LL.D., F.R.S.
Chemistry as an art has been practised from time immemorial,
and a great variety of what are, strictly speaking, chemical
products, such as metals, salts, acids, dyes, pigments, were made
long before the Christian era. Chemistry as a science, however,
is barely a century old. It is based upon the Atomic Theory, and
the idea of explaining chemical phenomena by means of the con¬
ception of atoms, foreshadowed by Newton, and more clearly
adumbrated by his followers Kiel, Hartley, Marzucchi and Higgins,
was first definitely stated by John Dalton during the first decade
of this century. The whole course of modern chemistry, however
complex and many-sided it may seem, is really one vast elabora¬
tion of the Atomic Theory. As Liebig has said : ‘ ‘ All our ideas
are so interwoven with Dalton’s theory that we cannot carry
ourselves back to the times in which that theory did not exist. ”
And yet this fundamental hypothesis, as understood by chemists,
had barely come of age when the Queen came to the throne ; it
was not much older at the time than she herself. The illustrious
philosopher who first gave precision to this idea was still living,
but stricken down at the time by the paralytic attack, the
beginning of the brain distintegration which seven years later
ended in his death. Sir Humphry Davy — a younger man than
Dalton — the pioneer in the then recently-discovered field of
electro-chemistry, and which to-day is yielding such splendid
fruit, had been dead only about eight years, as were Wollaston
and Thomas Young. All three, in fact, died at about the same
period, and all from affections of the brain. At the Royal
Institution he who has been styled the greatest of Davy’s dis¬
coveries reigned in Davy’s stead. Michael Faraday of revered
memory — blacksmith’s son, newspaper boy, bookbinder’s appren¬
tice, and Fullerian Professor of Chemistry — was then in his forty-
fifth year, in the full maturity of his intellectual power, and near
the meridian of his scientific glory. All his more important work
in chemistry — his discovery of benzene, his researches on the
liquefaction of the gases — had been accomplished, and he was
almost wholly engaged upon those great problems of electrical
science which have made the extraordinary development of applied
electricity, as we see it to-day in electrolytic decomposition, in
the electric light, and in the application of .electricity as a source
of power, alone possible. The Queen, in fact, may be said to have
witnessed the birth of this marvellous application of natural energy,
to have lived with it through its vigorous youth, and to have seen
the promise of a fruition so vast that no man can set bounds to it.
Think of the simple experiments out of which has grown the
mighty machinery of modern industrial electricity ? Try to
realise the difference between Faraday’s simple home-made
apparatus — his small copper discs, his bits of soft iron wound with
wire insulated with calico and twine — and the mighty dynamos
which are converting the energy of a “harnessed” Niagara into
heat and light and chemical action, and supplying power to a
continent ! And all this within the span of a single reign — within
the compass of a couple of generations. This astonishing move¬
ment is what historians will ever recognise as the characteristic
feature of the Victorian era. It has wholly changed the economic
and social condition, not only of our people, but of every country
which has had the intelligence and the wisdom to participate in it,
or the sagacity to avail itself of its fruits. It has reacted not only
upon industry, but on every department of intellectual effort. It
has changed, although hardly with a commensurate rapidity — for
there is no class so conservative as that of the schoolmaster — the
* From an address delivered at the East London Technical College, People’s
Palace, on the occasion of the distribution of science certificates, February 8,
1§S>T. With additions, — Reprinted from Knowledge,
face of our educational system. To judge what the change hag
been, let us try to realise how chemistry was taught in this country
in 1837. As a part of school education it was practically unknown,
although children whose parents had the good fortune to be
influenced by the teaching of such far-sighted men as Mr. Edge-
worth, had their curiosity stimulated and fed by occasional
lectures on science. As regards the older universities, at Oxford
there was Dr. Daubeny, an amiable and accomplished gentleman,
who was a professor of botany to chemists and a professor of che¬
mistry to botanists ; at Cambridge there was Professor Camming,
who lectured on chemistry, but interested himself mainly in elec¬
tricity. At neither place was there anything in the nature of a
laboratory which the student could attend. If the enterprising
undergraduate desired to familiarise himself with the facts of
chemistry by practical experiment, or sought to try and work out
an idea which might have occurred to him, he had to pursue his
inquiries in his own rooms and with such apparatus as his means
or his opportunities could command, to the imminent risk of his
furniture and to the dismay and disgust of his bedmaker. It was
under such conditions that the late Sir John Herschel discovered
the solvent action of silver salts unacted upon by light of what the
photographers know as “hypo” (sodium thiosulphate), and thereby
made photography possible.
In Scotland, Dr. Hope — whose name carries us back to the days
of phlogiston — still enjoyed at Edinburgh the fame as a lecturer
which he shared with Davy at the Royal Institution ; but no
tuition in practical chemistry, as a part of university training, was
ever thought of. Matters at Glasgow were a little better, and
Thomas Thomson would occasionally extend a brusque hospitality
to the student who aspired to the art and mystery of mineral
analysis, but no systematic instruction was ever attempted. The
youth with no knowledge of manipulative work, and with scarcely
an acquaintance with the forms even of chemical apparatus, was
regarded as a sort of laborant, and might be set, at the very
outset, to struggle with a zeolite, or to grapple with an atomic
weight determination, as best he might. This circumstance prob¬
ably serves to explain the character of much of the analytical work
which is connected with Thomson’s name, and which, happily
enough, has passed into oblivion.
In London there was the promise of better things. Thomas
Graham — who had already made his memorable discovery of the
law of gaseous diffusion whilst Professor of Chemistiy at Ander¬
son’s College in Glasgow, where he had established a school of
practical chemistry, and where he had as students the late James
Young, whose name is linked with the creation of the Scotch
paraffin oil industry, and the present Lord Plaj fair — had followed
Ure and Birkbeck to London, and had been elected to the chair of
chemistry at University College, Gower Street, up to that time
known as the University of London. Here as successor to Edward
Turner, a painstaking and even brilliant manipulator, whose
atomic weight work rivals that of Berzelius in point of conscien¬
tious accuracy, he created the School of Chemistry which, aided
by Fownes and Williamson, he made famous throughout Europe.
But it may be doubted whether in 1837 there were more than a
couple of dozen persons altogether in the British Isles receiving
systematic instruction in practical chemistry, and even that supply
was probably fully equal to the demand. There was, in fact, little
to tempt men to take up the study or practice of chemistry as a
means of livelihood. Professorships or teacherships were few in
number and poorly paid ; analytical chemistry, as a profession,
barely existed, although the “expert,” pace Ure, was not alto¬
gether unknown ; and chemical manufacturing was, for the most
part, in the hands of men to whom chemistry was an empirical art.
How things appeared to an intelligent and keen observer is well
illustrated by one of Liebig’s letters to Berzelius, in which he
recounts his impressions of England, which he had just visited.
Under date November 26, 1837, Liebig tells the Swedish chemist
that he had been some months in England, had seen a vast amount,
and learnt little. England, he says, is not the land of science; her
chemists are ashamed to call themselves chemists because the
apothecaries had appropriated the name. He was extraordinarily
pleased with us as a people and delighted with our hospitality and
welcome, but as regards our chemists — well, Graham was the only
exception, and he was precious. Liebig evidently considered that
Faraday could no longer be reckoned among the chemists.
But a little leaven was leavening the whole lump, and that
leaven was Liebig himself. Aided by the far-sighted munificence
of a German prince, he had succeeded in establishing the little
Giessen laboratory, and thither every seeker after chemical truth
512
PHARMACEUTICAL JOURNAL.
[June 12, 1897
and every aspirant for chemical fame bent his step3. Among these
early chemical pilgrims were Lord Playfair, Sir Henry Gilbert,
Professor Williamson, Dr. Gladstone — all happily still among us.
Others might be named, but the greater number have now passed
away. All of them, whether great or small, brought back from
Giessen something of the spirit and method which have made the
little laboratory on the banks of the Lahn famous in the history of
chemistry. The influence of Giessen has been as a seed which,
falling on good ground, has sprung up and multiplied an hundred¬
fold. That influence has made Germany pre-eminent in the world
of scientific chemistry, and may make her pre-eminent, if it has
not already done so, in the world of industrial chemistry. Luckily
for this country, Liebig’s influence has reacted also upon us. It
has had a profound effect on chemical activity, and on the develop¬
ment of chemical teaching in England. One of its first results was
seen in the founding, in 1841, of the Chemical Society, whose duty
and privilege it is to foster chemical inquiry and promote the
spread of chemical knowledge. The Society now numbers upwards
of two thousand members. How it is achieving its purpose may
be seen in the activity and interest of its meetings, in the extent
and value of its publications, and in the helpful hand it extends
to the investigator by the prudent administration of the funds
which have been placed at its disposal by the munificence of
private benefactors and public bodies.
Another notable result of Liebig’s influence on chemistry was
seen in the foundation, in 1845, of the Royal College of
Chemistry, of which Hofmann, one of his most distinguished
pupils, was invited to take charge — thanks largely to the action of
the late Prince Consort. What Hofmann, fired by the example of
Liebig and his own innate enthusiasm, did for chemistry in
England may be seen in the panegyric of Hofmann — the joint
work of Lord Playfair, Sir Frederick Abel, Dr. Perkin, and
Professor Armstrong, which appeared some little time ago in the
Journal of the Chemical Society. There is no more inspiriting or
instructive chapter in the history of chemistry in this country
than that which records the work of the Royal College of
Chemistry, and traces its influence on the development of pure
and applied science. Although Hofmann unfortunately left us,
his spirit and example still remain and actuate us. This spirit
has been carried into a hundred places of chemical instruction and
research in these islands. Let us pray that it may continue and
increase, for it is on its continuance and growth that the develop¬
ment of chemical science and chemical industry depends ; and in
so far as our national prosperity is connected with the chemical
arts our national prosperity depends on it also.
It is hardly necessary nowadays to show how closely the well¬
being of a community is connected with the chemical arts.
Chemistry and its applications concern us at every turn, for there
is scarcely a single industrial operation which could be named with
which this science has not some relations, either proximately or
remotely. There is a noble passage in one of Sir Humphry Davy’s
earlier lectures which well illustrates this point. The lesson has
been frequently urged upon us, but never more forcibly than by
Davy at the very beginning of this century. It is not often that
the theatre of the Royal Institution resounds with more eloquent
sentences than these : —
“The progression of physical science is much more connected
with your prosperity than is usually imagined. You owe to
experimental philosophy some of the most important and peculiar
of your advantages. It is not by foreign conquests chiefly that
you are become great, but by a conquest of nature in your own
country. It is not so much by colonisation that you have attained
your pre-eminence or wealth as by the cultivation of the riches of
your own soil. . . .
“ In every part of the world manufactures made from the mere
clay and pebbles of your soil may be found ; and to what is this
owing? To chemical arts and experiments. You have excelled
all other people in the products of industry. But why ? Because
you have assisted industry by science. Do not regard as indifferent
what is your true and greatest glory. Except in these respects,
and in the light of a pure system of faith, in what are you
superior to Athens or to Rome ? Do you carry away from them
the palm in liteiature and the fine arts ? Do you not rather glory —
and justly too — in being in these respects their imitators ? Is it
not demonstrated by the nature of your system of public educa¬
tion and by your popular amusements ? In what, then, are you
their superiors ? In everything connected with physical science—
with the experimental arts. These are your characteristics. Do
not neglect them. You have a Newton, who is the glory, not only
of your own country, but of the human race. You have a Bacon,
whose precepts may still be attended to with advantage. Shall
Englishmen slumber in that path which these great men have
opened, and be overtaken by their neighbours ? Say, rather, that
all assistance shall be given to their efforts ; that they shall be
attended to, encouraged, and supported.”
These words were spoken in 1809, and during all the turmoil
and political disquietude that marked the opening years of the
century. However willing and receptive the ears, tne time was
inopportune. The minds of the auditors might be convinced, but
their energies were preoccupied with the arts of war rather than
with those of industry and peace. A generation later, and when
Europe had settled down after the fall of Napoleon, Davy’s
teaching began to bear fruit. We have seen how far it had
matured at the time of the Queen’s accession, and in the years
immediately subsequent to it : how far has it been attended to and
supported since ?
As regards chemical education the difference is enormous.
There is not an important town in the kingdom in which chemistry
is not taught, and, on the whole, well taught. Almost every
manufacturing town in the country can show a public chemical
laboratory far better equipped with appliances for teaching, and
even research, than were the most famous laboratories of sixty
years ago. In the matter of the introduction of the teaching of
physical science into our schools, the force of public opinion is
gradually making itself felt, although the head master, as a rule,
hardly yet realises the full significance of Faraday’s weighty words
when he said : “I do think that the study of natural science is so
glorious a school for the mind that, with the laws impressed on all
created things by the Creator, and the wonderful unity and
stability of matter and the forces of matter, there cannot be a
better school for the education of the mind.”
Things, however, have improved since the time that Faraday
told the Public School Commissioners that the fact that the
natural knowledge which had been given to the world in such
abundance was untouched, and that no sufficient attempt was
being made to convey it to the young mind, growing up and
obtaining its first views of these things, was to him a matter so
strange that he found it difficult to understand. The opposition
which Faraday felt was so difficult to overcome, but which, he
added, he had not the least doubt in the world ought to be over¬
come, has been to some extent relaxed, and, in the curt but
characteristic language of the forms, “stinks” are at least
tolerated, even if they are not encouraged, in the curricula of most
public schools. It is, however, in the newer provincial colleges
that the teaching of chemistry has received its greatest develop¬
ment. Owens College, Manchester, founded more than forty years
ago, has become, mainly by the influence and organising power of
Sir Henry Roscoe, and of his successors, Profs. Dixon and Perkin,
one of the foremost schools of chemistry in the country. The
great success of Owens College has stimulated almost every large
town to provide itself with an institution of similar character, and
colleges of university type, all of them with well-equipped
chemical laboratories, are now to be found in Liverpool, Leeds,
Newcastle, Nottingham, Sheffield, Birmingham, Bristol, Cardiff,
Aberystwith, Bangor, and Dundee. Institutions of a less
ambitious type, although provided for the most part with good
accommodation for instruction in practical chemistry, are met
with, amongst other places, at Bradford, Huddersfield, Preston,
Oldham, Chester, Newcastle-under-Lyme, Portsmouth, Southamp¬
ton, Camborne, Edinburgh, and Glasgow. All the older
universities have followed suit. The university laboratory at
Cambridge is one of the best arranged in the kingdom ; Edinburgh
is also admirably provided with the means of pursuing research
in the higher branches of the science, as are the recently
opened laboratories of St. Andrew’s and Aberdeen. With the
exception of University and King’s Colleges, and the Royal College
of Science (into which has been merged the chemical teaching of
the Royal College of Chemistry and of the Royal School of Mines
in Jermyn Street), all the more important schools of chemistry in
London are comparatively modern. The City and Guilds Institute
in South Kensington, built in 1883, and the associated Institute in
Finsbury, erected a short time previously, owe their origin to the
action of the City companies, who have been instrumental also in
founding or in assisting a number of the Polytechnics scattered
round London, such as the Goldsmiths’ Institute at New Cross, the •
Battersea Polytechnic, and the East London Technical College,
which has its home in the People’s Palace. A great number of the
Polytechnics and minor colleges above named are dependent upon
June 12, 1897]
PHARMACEUTICAL JOURNAL,
Jm
513
aid from the Department of Science and Art, or are supported by
funds at the disposal of County Councils. Indeed, the liberation
of the “ beer ” money, and its very general application to so-called
technical education, has had a very marked effect in diffusing a
knowledge of the elementary principles of science. Whether the
money is in all cases spent to the best advantage may be open to
question. There is, indeed, little doubt that more real good might
be accomplished by a better method of allocating the amount, as,
for example, by some system of co-ordinating County Councils
within specified areas, with a view of subsidising secondary schools
and the colleges of university type situated within the area. This,
however, as a part of the general question of what is the best
method of dealing with secondary education in this country, is too
complex a matter to be dealt with now. It is pretty plain that
before many more years have passed a Parliamentary inquiry will
be demanded on the working of the present method of allowing
each County Council to do practically what it likes with what it
imagines to be its own.
No record of the educational work in science of the last sixty
years would be complete without some reference to South Ken¬
sington. The system and its results have been, at times, the sub¬
ject of much hostile, and, it must be added, not very well-informed
or altogether impartial criticism. But I venture to think that any
dispassionate and unprejudiced inquirer who will take the trouble
to make himself master of the subject, will be constrained to allow
that the Department has done great and permanent service to the
cause of scientific education in this country. The general standard
of scientific knowledge has been enormously increased by the
hundreds of science classes created by its agency, and which other¬
wise would have been non-existent. How far it will be allowed to
continue on its present footing remains to be seen. It is, however,
certain that the science teaching which it has called into existence,
and which it has fostered and encouraged, is too much an integral
and essential part of our educational system to be abolished, what¬
ever may be the machinery of State by which it is to be directed
and controlled in future.
What Englishmen of science have done in the way of chemical
inquiry and discovery during the Victorian era, the pages of the
Philosophical Transactions and of the Journal of the Chemical Society
abundantly indicate. The names of Faraday, Graham, William¬
son, Hofmann, Frankland, Miller, Schunck, Stenhouse, Brodie,
Andrews, Gladstone, Crookes, Perkin, De la Rue, Muller, Roscoe,
Schorlemmer, Rayleigh, Ramsay, Dewar, are associated with
experimental investigations which mark points of departure in the
history of chemical progress during the last sixty years. These
investigations range over every department of chemical inquiry,
from the isolation of new elements — the preparation of new com¬
pounds of great theoretic and industrial importance — to the
discovery of new generalisations, and the recognition of important
physico-chemical laws.
As regards originality in the application of chemistry to practice,
our record is hardly less brilliant, although in too many cases it
has been given to other nations — and in particular to Germany —
to gather the fruit which ought to have been ours. It is interesting
to note that the ammonia-soda process was patented by Dyar and
Hemming in the first years of the Queen’s reign, and was worked
by the Muspratts as early as 1839 ; but it was left to two Belgian
engineers to secure for this method of manufacturing alkali the
freat commercial success which it now enjoys. The discovery of
enzene by Faraday was the first step in the history of the coal-tar
colour manufacture ; the second step was taken by Mansfield, at
the sacrifice of his life, in working out the industrial isolation of
the hydrocarbon ; whilst the third was due to Perkin, when, by
the discovery of mauve, he revealed the enormous wealth of
colouring matter which was latent in coal-tar. In spite of the
labours and example of Medlock and of Nicholson, the importance
of this great branch of industrial chemistry was not recognised by
manufacturing chemists in this country, and its present extra¬
ordinary development is due to Germany, which has spent upon it
some of the ablest chemical talent it possesses. It is rather by the
development and extension of well-established processes, depending
on comparatively simple chemical principles, that our progress in
the chemical arts is to be measured ; for our staple chemical
industries remain very much what they were at the beginning of
the Queen’s reign. The industrial chemistry of chlorine may be
said to have been worked out by Englishmen, and the names of
Gossage, Weldon, and Deacon are pre-eminently associated with
the growth of this branch of chemical manufacture. The Mus¬
pratts manufactured Liebig’s patent manure in 1843, and this
marks the beginning of the large trade in chemical fertilisers,
which has been entirely developed during the Queen’s reign.
Perhaps the best measure of the progress of applied chemistry in
this kingdom during the past sixty years may be gathered from
the difference in the amounts of oil of vitriol manufactured in 1837
and at the present time. The great value of sulphuric acid as an
index of the prosperity of the chemical arts arises from the circum¬
stance that there is no other single chemical product that is so
largely concerned in the manufacture, directly or indirectly, of
other chemical substances. To-day sulphuric acid is manufactured
with an almost quantitative precision, thanks very largely to the
introduction of the Glover tower, which it is not too much to say
effected a revolution in this great industry.
What the future has in store for us remains to be seen. The
more general introduction of electrical processes into chemical
manufacturing is bound to effect great changes. The application
of electrical energy has completely altered the aspect of the
metallurgy of aluminum, copper, and the alkali metals, and it
now threatens the supremacy of the established methods of manu¬
facturing alkali and chlorine.
So far as can be seen, there is no immediate hope that this
country will be able to compete with Germany in the manufacture
of those products which are the direct outcome of the application
of the higher and more recondite branches of chemical science to
industry, nor will there be even the prospective hope until our
manufacturers, as a body, bring the spirit of science into their
work, and show a greater receptivity and a more widespread
desire to turn the ever-growing development of the science to
practical account.
NOTES AND FORMULA.
( Specially abstracted for the Pharniaceidical J ournal. )
Improved Linimentum Calamin*e.
Calamine, pure ......
Oxide of Zinc .
Lime Water .
Oil of Sweet Almonds
. 20 grains.
. 15 grains.
. \ ounce.
to make 1 fl. oz.
■ — Skinner in Brit. Journ. Derm., lxii., 97-
Extemporaneous Preparation of Chlorine Water.
The following method is recommended by Griggl for the extern*
poraneous preparation of chlorine water in the cold. The reagents
are oxalic acid, 1*8; lead peroxide, 2-39; and calcium chloride,
249 ; with water, 200. Insoluble calcium and lead oxalates result,
while the filtrate is practically saturated with chlorine : —
2(C.2H2042H20) Pb08 (CaCl26H20)
1-80 + 2-39 + 2-19
CaC204 + PbC204 + 12H20 + Cl2.
— Pliarm. Era, xvii., 512 (after Bollet. Farmaceut. Chirn.).
Ointment of Starch Iodide.
Oefele employs the following formula to prepare an antiseptic
ointment of starch iodide :■ —
Starch Iodide .
Lanolin .
Fresh White of One Egg.
Boiled Yolk of One Egg.
}
Of each 5 grammes.
Mix intimately to make an ointment. — Bull. de la Soc. de Pharttu
Debrux., xli., 120.
Preserving Tomatoes.
Take the best, firmest, and not over-ripe fruits, scald and skin
carefully, take the stem out with a penknife, being careful not to
cut the tomato and let the juice out ; place in a jar, some with the
stem and some with the flower end next to the glass. Cook some
juice, adding a little salt, and pour over the whole tomatoes until
the jar is nearly full. Place the jars in a common fish-boiler of
oblong shape, with a cloth at the bottom to protect them from the
heat of the. fire, which is liable to crack them. Fill the boiler
with cold water and bring to nearly boiling point, or sufficient^ to
heat the tomatoes clear through, and seal the jars. In about five
minutes take off the jar cover to let gas out and allow the tomatoes
to settle ; then fill up with boiled juice and seal again. Next day
screw the tops tight and put away in a dark, cool place.— Agricult,
Journ., x., 320.
514
PHARMACEUTICAL JOURNAL.
[JiTNE 12, 1897
THE STUDENTS’ PAGE.
EXPLANATORY NOTES ON THE PHARMACOPOEIA.
Fel Bovinum Purificatum. — Treatment with alcohol precipi¬
tates chiefly mucin, and the filtrate contains the bile salts (glyco-
cholate and taurocholate of sodium), lecithin (a complex fat), and
cholesterin (a monatomic alcohol). The absence of precipitate on
the addition of rectified spirit to its watery solution shows that
the purification with alcohol has been properly carried out.
Ferbi Carbon as Saccharata. — Ferrous carbonate, like other
ferrous salts, is readily oxidised by exposure to air, especially in
presence of water. The directions for preparing this compound are
intended to diminish, as far as possible, the extent of this oxidation,
so as to obtain as much as possible unoxidised ferrous carbonate in
the finished product. Ammonium carbonate is used in preference
to the cheaper carbonates of potassium or sodium. If either of the
latter be used, the precipitated ferrous carbonate carries down some
alkaline salt with it, and this cannot be easily removed by simply
washing. When ammonium carbonate is used, the iron pre¬
cipitate is readily washed free from ammonium salt. Note that
the precipitate is washed by decantation, to avoid exposure to air
on a filter. Boiling water obviously washes out soluble salts
more thoroughly than cold ; boiling, also, would have expelled
any oxygen dissolved in the water. Note that the sugar
is mixed with the moist precipitate. The addition of
the sugar retards to a large extent the oxidation which would
occur if the carbonate be dried alone. The finished product
slowly oxidises when kept, and the oxidation is attended with a
change of colour from grey-green to brown. The test with
barium chloride shows the absence of more than traces of
ammonium sulphate. To remove these last traces prolonged
washing would be necessary, and this is undesirable on account
of the opportunity for oxidation it would afford. In the quanti¬
tative determination of ferrous salt by vol. sol. of potassium
bichromate, the insoluble carbonate is dissolved by means of phos¬
phoric acid. Hydrochloric or sulphuric acid produce invert sugar
from cane sugar more easily than phosphoric acid, and invert sugar is
attacked by chromic acid (produced on the addition of bichromate
solution to a solution containing free acid). The presence of any
substance having a reducing action on the bichromate would
introduce an error into the process, since all the volumetric solution
added would not be used up in the reaction upon which the cal¬
culation is based, viz. , the conversion of ferrous into ferric salt.
Ferri et Ammonii Citras. — The “scale” compounds of iron
possess a special value in medicine, since they are less astringent
than the ordinary salts of iron and afford also a means of giving iron
in neutral or alkaline solution. The behaviour of iron and the other
metals of the same group towards certain organic acids (and other
organic bodies containing hydroxyl groups, e.g. , sugar and glycerin)
has an important bearing upon practfcal analysis, because in
presence of these substances the hydrates are not precipitated
on the addition of ammonia, soluble double compounds being
produced. Hence the necessity in qualitative analysis for precipi¬
tating the iron as sulphide with ammonium sulphide, unless the
absence of these organic substances has been determined. Note
that in preparing the ferric hydrate the persulphate solution is
poured into the excess of ammonia. If the order be reversed some
oxysulphate of iron is carried down with the ferric hydrate, and
interferes with the brilliancy of the scales. In the tests, after
treatment with potash solution the filtrate should contain
nothing but potassium citrate, with excess of potassium hydrate,
the ammonia having been expelled and the iron precipitated
as hydrate. Formation of a crystalline deposit in this filtrate,
when it is acidified with acetic acid, would indicate substitution of
(the usually cheaper) tartaric acid for citric acid in manufacture.
Treatment with potash would then result in the filtrate containing
potassium tartrate, and on the addition of excess of acetic acid the
sparingly soluble acid tartrate (cream of tartar) is precipitated —
kah4o6+hc2h3o2 _ KHC4H406+K02H302.
The absence of alkalinity in the ash shows the absence of potas¬
sium compounds, since organic salts of this metal leave an alkaline
residue of carbonate of potassium, while ammonium salts are
entirely volatilised. Compare both these tests with similar ones
given under ferrum tartaratum.
Ferri Peroxidum Hydratum. — Ferric hydrate, Fe26(OH), is
precipitated on the addition of solution of ferric sulphate to sodium
hydrate. The washed precipitate loses water when dried at
100° C., forming a compound intermediate between the oxide,
Fe.203, and the hydrate. This hydrated oxide gives up more water
when heated to redness ; the oxide which is left is difficultly soluble
in acids, and is not suitable for medicinal purposes. The evolution
of about 10 per cent, of moisture on ignition, required by the B.P.
test, corresponds to the formula Fe202(0H)2.
Fe202(0H)2 = Fe„0, + H,0.
Fe202(0H)2(M. Wt., 178) loses H20(M. Wt., 18).
178 : 18 : : 100 : 10T
(NH4)3HP04
MgS04
NH4HO .
Arseniate of iron gives a
M
>4
oj
Ferri Phosphas. — In the official test precipitation by both ferro-
and ferri-cyanide of potassium shows the presence of both ferric
and ferrous phosphate. Addition of tartaric acid before excess of
ammonia is to prevent the reprecipitation of iron by the latter
when the acid solution is made alkaline, a soluble ‘ * scale-com¬
pound” being formed. The crystalline precipitate produced
by the addition of ammonio-sulphate of magnesium is the
characteristic ammonio-magnesium phosphate, which is soluble
in acids, and hence must be precipitated in a neutral solu¬
tion, or better still, in presence of excess of ammonia, in
which it is even less soluble than in plain water. The alkaline
liquid contains ammonio-tartrate of iron, ammonium chloride, and
ammonium phosphate.
( Mg(NH4)P04
= 4 (NH4)2so4
l H2°
similar precipitate of ammonio-
magnesium arseniate, MgNH4As04 (note analogy of arsenic and
phosphoric acids and cf. also molybdate test for these two acids).
The copper foil test, in acid solution, distinguishes the two,
since the arseniate is reduced and deposits a dark film of arsenic
on the copper, while the phosphate is unaffected.
Ferrum Redactum. — Ferric oxide at a red heat is reduced by
hydrogen to the metallic state with formation of water,
Fe?03 + 3H2 = 2Fe + 3H20.
Note that this is a good example of a reversible chemical reaction,
since steam passed over heated iron forms oxide of iron and water.
If ferric oxide be heated in a closed tube containing hydrogen the
reaction shown by the equation above proceeds to a limited
extent and then stops, a condition of equilibrium being
attained owing to the retention of the water vapour
and the consequent reversal of the first reaction. The extent to
which the first reaction proceeds is chiefly conditioned by the
relative amount of oxide and hydrogen present. But in the pro¬
cess described in the Pharmacopoeia a current of dry hydrogen is
passed continually over the oxide ; the water formed is thus swept
out of the tube by the excess of hydrogen and the reduction of the
oxide proceeds. On the other hand, if steam be passed Over heated
iron, the hydrogen liberated by the oxidation of the metal is carried
away by the excess of steam, and the oxidation of the iron pro¬
ceeds continuously. The ferric oxide is directed to be obtained
from the perchloride, not the persulphate, although the latter is
the more economical way. The explanation for this is found in
the tendency of ferric hydrate when precipitated from the sulphate
to carry down and obstinately retain a small quantity of sulphate.
During the subsequent ignition in hydrogen the sulphate is reduced
to sulphide. When reduced iron containing sulphide of iron is
administered, the hydrochloric acid in the gastric juice dissolves
the latter and sulphuretted hydrogen is evolved, imparting to the
breath of the patient its well-known objectionable odour — •
FeS + 2HC1 = FeCl2 + H2S.
The quantitative test with iodine is not satisfactory. Iodine
attacks the metallic iron forming soluble ferrous iodide,
while any oxide present is left undissolved, and may
be separated by filtration, washed, and weighed. During the
digestion, however, some of the ferrous iodide is oxidised to an
insoluble ferric oxy-iodide, which is consequently precipitated and
weighed with the oxide. The process therefore yields a larger
insoluble residue than corresponds to the amount of oxide actually
present. Another process is to heat the reduced iron with excess
of copper sulphate solution. The oxide is not affected, as in the
previous process, while the metallic iron goes into solution as
ferrous sulphate, an equivalent quantity of metallic copper
being precipitated : — CuS04 + Fe = FeS04 + Cu.
The filtrate containing ferrous sulphate (with excess of copper
sulphate, which does not interfere) is then acidulated and titrated
with volumetric solution of potassium permanganate, from which
one can calculate the amount of ferrous sulphate in the filtrate,
and consequently of metallic iron obtained from the reduced iron
taken (vide Pharmaceutical Journal June 21, 1890, p. 1053).
June 12, 1897J
Pharmaceutical journal.
515
Pharmaceutical Journal.
A Weekly Record of Pharmacy and Allied Sciences.
ESTABLISHED 1841.
Editorial Office: 17, BLOOMSBURY SQUARE, W.C.
Publishing a^d Advertising Office : 5, SERLE STREET, W.C.
LONDON : SATURDAY, JUNE 12, 1897.
THE POSITION OF PHARMACISTS IN THE
SOCIAL SCALE.
The fact that the writer of an article in a London daily
paper, in discussing the encroachment of drapers upon other
trades, incidentally classes chemists with toy merchants and
stationers, counts for little in itself perhaps, hut it re directs at¬
tention to the delicate problem of the social status of pharma¬
cists. It is well known that none of the petty vanities which
afflict mankind are more far-reaching in their influence than
that which instigates them to have their position in the social
scale strictly defined and if possible over-estimated, and
though the passage of a few brief years reduces everyone to
the same uniform level, the matter of precedence during life
is apt to assume an artificial importance which is quite
disproportionate to the advantages likely to accrue. Never¬
theless, in numerous instances peace of mind and accompany¬
ing bodily comfort are ruthlessly sacrificed if, by the
expenditure of badly-spared energy or a little judicious
string pulling, the individual can secure recognition as
belonging to a “caste” of assumed superiority to that with
which he has been wont to be associated. The instinct of
self-preservation may be at the root of this tendency ; for, to
a certain extent, there is little doubt that worldly advan¬
tages do flow in greater proportion in the direction of those
who occupy positions above the social zero, and the higher
those positions can be made to appear the more satisfactory,
probably, will be the result attained from a material point
of view. Though whether the game is worth the candle
is quite another matter.
But, however this may be, it is necessary that persons
who appreciate class and its privileges should set out with
the axiom in view, that the estimation in which an
individual is held by his fellows is greatly influenced
by the estimate he puts upon himself. This has repeatedly
been proved to be true, and to a degree that is fully ap¬
preciated only by the few wfflo skilfully turn it to their own
personal profit. The man who makes himself cheap will
be estimated accordingly by those with whom he comes
in contact, whilst he who puts an exaggerated value
upon his own position and capabilities is more likely to
secure a higher level in the opinion of others than would
be the case were ho recognised simply for w'hat he is. The
modest man, of course, suffers in comparison with pushing
individuals possessing much inferior personality, for dread
of the mental unrest that would afflict him if ho thought he
were reaping advantage under false pretences acts as an effectual
deterrent to lofty self-appreciation in his case. Taking one
thing with another, however, the advantages and dis-
advantages of his particular line of conduct probably balance
so far as he is concerned. It may be that he will be least
likely, for example, to forget that pharmacists, like medical
men, follow a calling which partakes of the nature of a pro^
fession as well as of a trade, and that his business, if
rightly conducted, should not show its commercial side most
prominently.
To return to our text, the pharmacist’s position in the
social scale must of necessity depend to a very great extent
upon himself. If he is classed with toy merchants, stationers,
drapers, grocers, and other tradesmen —all estimable persons
no doubt in their way — he has only himself to blame, as it is
due to his adoption of thfflr business methods. The fact of
keeping an 'open shop perhaps still entails some disad¬
vantage from a social point of view at the outset, and it is
not clear that this disadvantage can be entirely neutralised
in the pharmacist’s case. He may, however, reduce it to a
minimum, but only by refraining absolutely from the methods
of other shopkeepers. If he is content with the results
obtained by setting out his shop window so as to attract the
attention of passers-by to his wares, well and good. But he
must not then expect to take rank with the local physician
and surgeon who scrupulously dissociate themselves from
everything that savours in the least of self-advertise¬
ment. On the other hand, by carrying the true professional
spirit into all his dealings, he cannot fail to establish himself
in a position that will demand and secure recognition as
effectively as in the case of any other professional class. It
would appear, therefore, that to those who value social
position those dizzy heights are always ’ open, and the
elevation to which they may attain is invariably if roughly
commensurate with the efforts they are prepared to put forth.
The ultimate result, as already remarked, will be the same for
all men. Meanwhile, however, he who is not above such
vanities, has the way clearly marked out for him to attain
social status and its concomitant advantages, such as they are.
TELEGRAPHY WITHOUT WIRES.
Nothing more remarkable has been witnessed during the
past sixty years than the rapid development of methods of
communication by the aid of electricity, but it is safe to assume
that we have as yet but touched the verge of the subject. The
lecture by Mr. W. II. Preece, reported at page 521, brings the
record up to date, and shows that, marvellous as past progress
has been, still greater marvels may be looked for, whilst some
are actually on the point of practical realisation. The chief
difficulty in the way of extending telegraphic communication
to many places has been due to physical obstacles prevent¬
ing the extension of the necessary wires. These, it
is now shown, can be dispensed with in many
instances. To take the case of Sark, the smallest of the
four principal Channel Islands, it has up to the present been
in possession of no system of telegraphic communication
with the outside world. But this undesirable state of affairs
will soon be a thing of the past, for Mr. Preece is about to
establish the new Marconi system of signalling between
Sark and Guernsey. As stated by Mr. Preece in his
lecture, Marconi messages have been sent between Penarth
and ’islands in the Bristol Channel, more than five miles dis¬
tant, and there seems no reason, therefore, why Sark should
any longer be in the position of frequent isolation from the
outside world, as is now invariably the case in bad weather.
516
PHARMACEUTICAL JOURNAL:
[June 12, 189?
ANNOTATIONS.
Grocers are not Attracted by the P. A.T.A., if we may judge
from reports of meetings that have come to hand, and perhaps,
after all, there may be little reason to fear trouble resulting from
the “ unholy alliance” which is so strongly denounced by Messrs.
Atkinson, Hyslop, and others. The fact of the matter is that
grocers regard the whole affair as an attempt to induce them to
help chemists to recover profits that have been thrown away or
otherwise lost during the course of years, and they fail, therefore,
to see that the matter interests them. It must not be overlooked
that whilst chemists and druggists have practically built up the
trade in proprietary medicines and in many cases, unfortunately, have
come to depend upon that branch of their business, grocers at first
took up the sale of those articles as profitable extras only, whilst
they subsequently found that to offer them at reduced prices acted as
an inducement to customers. At the present time this alien trade
is worth little or nothing to grocers, and except in so far as it is a
convenience to their customers to keep a stock of proprietary
medicines, they would probably be glad to get rid of them alto¬
gether as a nuisance.
At a Meeting of tiie Blackburn Grocers’ Association, the
Chairman, in commenting on the receipt of a letter from Mr. Glyn-
Jones, said he did not see why the members of the Association
should go out of their way to assist manufacturers or chemists in
fixing prices at a higher rate than formerly. Chemists latterly
had not been friends of the grocer, and if they wanted to go hand
in hand with the grocers, they must make concessions to the
latter. Another speaker said that in years gone jby chemists had
done a grand trade. They had, however, cut down proprietary
articles until their profits were almost nil, and now they were
going to try to get them up again. He did not see why grocers
should help them. The tone of the meeting was clearly
indicated by these speakers, and others agreed that they ought
not to encourage chemists in this matter. Chemists, they pointed
out, have no interest in the prosperity of the grocery trade, and
ultimately it was decided by those present not to join the new
Association.
At Cardiff again, at a meeting of the local grocers’ associa¬
tion, it was pointed out that this was the old difficulty over again
—that of the regulation of prices — upon which a great many
associations had already split. Utterance was given to the fear
that this anti-cutting scheme would be injurious to grocers, from
the fact that a chemist would be able to substitute articles of his
own preparation in lieu of many proprietary medicines, and
sell them at prices below those at which the latter could be
retailed. The Chairman thought the scheme was fraught with
many difficulties, and as opinion amongst their own members was so
divided, he suggested that the less they had to do with it the better.
One member did not see that there was a great deal to be achieved by
the scheme. If a man were determined to cut, cut he would, and he
did not see how they could stop him. Before they could regulate
prices they must get every grocer and chemist unanimous on the
subject. Another view expressed was that a man has a perfect
right to conduct his business according to his own ideas, and that
if grocers tied their hands by joining this anti-cutting associa¬
tion, they might most likely have next door to them a cutting
chemist who sold many of the articles they themselves sold.
Chemists had already gone into the tea and soap trade, and sold
pretty nearly everything that a grocer handled ; and it would be
next to madness to tie their hands and so render themselves
incapable of competing successfully against such traders. Finally,
it was agreed that the Association should strenuously oppose the
scheme proposed by the Proprietary Articles Trade Association, and
request the delegates to the Liverpool Conference to vote against
its adoption.
Some Applications of Photography were illustrated by Mr.
E. J. Wall in an exceedingly interesting manner, at the social
evening of the School of Pharmacy Students’ Association, held on
Friday, J une 4. The lecture assumed the narrowest possible limits,
no more being said, in fact, than was required to explain the bearing
upon the subject of the numerous lantern slides exhibited. The
great dependence of modern science and art upon photography was
clearly exemplified, and all who witnessed the demonstration were
highly delighted with the evening’s entertainment. Mr. Wall is
an experienced lecturer, with a thorough grasp of everything
connected with photography, and doubtless many who heard him
on this occasion will be glad to have a further opportunity of
listening to an exposition by him of the same subject.
Mr. Alexander Sutherland, whose death we regret to record,
was an expert linguist, and could speak and read several European
languages. He spent some years in Rangoon, where he studied
Chinese and other Oriental languages, and he also knew Hebrew and
Syriac, whilst he was also a great student of history, philosophy, and
sociology. This was all in addition to an intimate knowledge of prac¬
tical pharmacy and materia medica and a more than average know¬
ledge of chemistry and botany. Though of a bright, genial, and
hopeful temperament, he possessed a very delicate constitution,
which effectually debarred him against rising to the dis¬
tinguished position which his talents otherwise would assuredly
have secured him. Feeling the need of quietness and rest he retired
about a year ago to his native island of Unst, the most northern
of the Shetland group, where he opened a small pharmacy, the
most northerly in the British Isles. But he had to struggle with
feeble health, and he died somewhat suddenly of chest disease on
the 24th ult. His address as President of the Edinburgh Chemists’
Assistants’ Association in 1894 was a good example of his thoughtful
mind and singularly well-balanced judgment. From time to time
he contributed similar papers to the Association, the last being in
1896, on “ The Irreducible Minimum — A Study.”
A Sterilised and Humanised Milk Factory has been erected
at Fodbank, Dunfermline, by Mr. G. M. Wilson, who has secured
the right to manufacture by the Gartner patent for a term of years,
The apparatus employed is described as being of the latest and
most approved type. The milk arrives at the works from neigh¬
bouring farms at an early hour in the morning, and before a drop
of it is put through the sterilising process it is tested to see that it
is up to the standard of quality required. After the testing pro¬
cess is finished, the milk is hoisted to the top of the building, and
emptied into a vat, whence it descends through filters to the
lower floor, and is there bottled. The bottles are all supplied with
hermetically sealed stoppers, and after being subjected to a tem¬
perature calculated to bring about complete sterilisation of their
contents, they are put through a cooling process. The sterilised
milk is simply purified by complete filtration, and rendered aseptic
by the heating process, but the humanised milk for infants also
has the proportions of casein, fat, and sugar adjusted to a definite
standard,
June 12, 1897]
PHARMACEUTICAL JOURNAL.
517
Matrimony and the Income Tax are often associated and,
in future, those who are fortunate enough to have wives
possessing or earning an income will have cause to bless
the name of Bartley. The honourable member for North Islington
is not unknown to fame, but his latest achievement of forcing
upon the Chancellor of the Exchequer the acceptance of
an amendment to the Finance Bill in favour of married
persons, greatly enhances his Parliamentary reputation. The effect
of his amendment will be that husbands and wives earning sepa¬
rate incomes aggregating less than £500 a year will be allowed to
return each income separately, and they will each be entitled to
claim the statutory abatement of £160. Hitherto the joint
income has been subject to only one deduction. Mr. Bartley is
making his success known through the medium of the Press, and
we cannot grudge him his perfectly justifiable pride in having
triumphed.
A School of Ethics for London would seem a large order, but
the Daily Telegraph states that a movement is on foot to form such
a school. It is intended to do for ethics and social philosophy
in London what existing schools of economics do for their particular
subject, though necessarily upon a smaller scale. The subjects of
the lectures will embrace psychology, the theory and history of
ethics, political philosophy, the history of political theory, and
there may be added special classes for the study of the great
philosophical classics. It is anticipated that the services of
lecturers from Oxford and Cambridge Universities would, amongst
others, be available, and it has been suggested that the proposed
school might with advantage be connected with some one or other
of the existing colleges. An influential general committee has
been formed, and steps have been taken to ascertain what financial
support is likely to be forthcoming. The Hon. Secretary (pro tem. )
is Mr. J. H. Muirhead, 30, Aynhoe Road, West Kensington, W. ;
and those among our readers who are burning to impose business
restrictions upon themselves, in the form of so-called ethical
standards, may find it worth their while to communicate with him.
The Dietary of Cyclists is a matter of considerable import¬
ance, and it is interesting, therefore, to note the opinion of Dr.
Lucas ChampionnRre, of Paris, who has devoted a good deal of
attention to the medical aspects of cycling, with regard to the
food taken by those who took part in the recent Paris-Bordeaux
contest. The competitors — Ri viere and Cordang — did not eat food
containing nitrogen, and they were right, observes Dr. Champion-
niere. But though they did not eat they drank enormous quantities
of liquid— tea, beef-tea, and milk — to replace the liquid or weight
lost by perspiration. It is useless, he says, to eat during violent
exercise, but it is important to drink, and if the body is in good
working order the only result of the effort is a decrease in weight.
The British Medical Journal thinks this is right as regards the
quality of food required on a long-distance contest.
Poisoned by Buttercups is a far from inconceivable occur¬
rence, though the Lancaster coroner, in holding an inquiry last
week, referred to such an instance as one of the most extra¬
ordinary poisoning cases that had come under his notice. A boy,
aged four, named William Foxcroft, ate some buttercups, and
died in a few hours from irritant poisoning. This is not at all
surprising, as it is well known that buttercups belong to a class of
plants many of which are extremely poisonouss. Some species,
such as llanunculus Jlammula and A. sceleratus are known to
possess vesicant properties, and the former is doubtless often fatal
to cattle,
The Age of the Earth as an Abode Fitted for Life was
the subject of a recent address by Lord Kelvin, who, in proceeding
to adduce grounds why there should be a definite beginning, as
there would be a definite end, to this world as an abode of life,
re-stated a number of arguments he had brought forward thirty
years ago. The doctrine of uniformity in geology shows that if
heat had been uniformly conducted out of the earth at its present
yearly rate the globe twenty thousand million years ago would
have been a molten, if not a gaseous, mass. Another argument
against the huge lengths of time required by the older geologists
is furnished by the constantly diminishing velocity of the earth’s
rotation owing to the tides. One thousand million years ago the
earth was revolving faster than at present, and consequently the
centrifugal force was greater. If the globe had become con¬
solidated when travelling at this faster rate, it would have
possessed greater oblateness, and the length of its equatorial radius
would have been six and a half kilometres more than at present.
To judge by the properties of rocks and by underground tempera¬
tures, the date of the solidification of the earth was most probably
twenty or thirty million years ago.
As to the Origin of the Atmosphere, at the time of solidi¬
fication there can have been no free oxygen, as far as can
be seen, and no chemical reaction by which it would be
liberated. Vegetable life and sunlight must have come into
play to prepare the atmosphere in the course of a few hundred
or thousand years. A serious geological question is the mode
of production of the ocean depths and the eminences of the
continents. Many phenomena are doubtless due to strain on cool¬
ing, but that does not afford sufficient explanation in this case.
The cause is probably to be found in change of density by crystal¬
lisation. Perhaps the strongest argument against unlimited
geological time is afforded by consideration- of the heat of the sun,
which, according to the most recent researches and corrections,
may have illuminated the earth for somewhere about twenty
million years. The latest geological estimate of the time required
for the formation of all strata since the beginning of the Cambrian
rocks is seventeen million years, and Lord Kelvin thinks he can
scarcely be described as merely a malicious physicist trying to
curb the aspirations of the biologists when he says that the earth
cannot have been a habitable globe for more than thirty million
years.
The Position of Naval Storekeeper is a subject concerning
which readers write to us from time to time, and a recent query
on the subject was referred to a correspondent who is in a position
to speak authoritatively about it. Assistant storekeepers,
he observes, are entered between the age of eighteen and
twenty-one years. To each vacancy the average number of
candidates is eight. Nominations are not required. The
examinations are competitive, and the compulsory subjects are
arithmetic, English composition, writing, dictation, and precis.
The voluntary subjects are Latin, French, Euclid, and algebra.
The necessary information for postal tuition and their fees may
be obtained from the Secretary, King’s College, London. All
information concerning vacancies, salaries, etc., will be furnished
on application to the Secretary, Civil Service Commission
Cannon Row, London. There are some fifteen vacancies for
these appointments during the year, under the designations of
assistant cashiers, assistantexpenseaccounts officers, assistant naval
storekeepers, assistant victualling storekeepers. The salaries
and examinations are identical. The pay is progressive by
annual increments of £10 up to £350, unless promotion to deputy
518
PHARMACEUTICAL JOURNAL.
[June 12, 1897
takes place, which is frequently the case, when it begins at £350
and rises to £500, afterwards advancing from £500 to £700 as store¬
keepers, etc. , and finally in the case of the three directors from
£800, by increments of £50 a year, to £1000. It will be observed
that one of these young men can have completed four years’
service before it is possible for the dispenser to get his qualifica¬
tion to enable him to enter. The dispenser’s increase of pay at
the end of five years is £9, so that the assistant storekeepers and
dispensers at twenty-seven years of age will receive £190 and £109
respectively. A dispenser works on an average seventy hours a
week exclusive of night work, while the storekeeping branch does
thirty-five hours’ work only with neither night nor Sunday duties.
The Museums Association is amongst the first to hold its
annual meeting this year, and the programme of proceedings is an
extremely attractive one. On Tuesday, July 6, the reception room
at the University Museum will be open from 12 to 6 p.m., and the
President, in Exeter College, invites members to a garden party,
from 9 to 12 p.m. On the following day the President will give a
brief address in opening the Session, the reading and discussion of
papers will follow in the theatre of the Ashmolean Museum, and
subsequently visits will be paid to the various museums under the
guidance of the respective Curators. The day’s business will
conclude with the Association dinner at 7.30 p.m. On Thursday,
July 8, the reading and discussion of papers will be resumed and
visits be paid to museums as before, whilst Mr. Arthur J. Evans
and Professor P. Gardner invite members to an “At Home” in
the Ashmolean Museum in the evening. On the last day of the
meeting the general business meeting will be held. The Colleges,
with their chapels, halls, and gardens, will be open to the visitors,
and there is ample opportunity for river excursions. Happy
Curators to spend so pleasant a holiday amid such interesting
surroundings !
The British Institute of Public Health announces a meeting
to be held in the Guildhall, Londou, on Wednesday, June 16, at
3 p.m., when an address will be moved to the Queen in connection
with the great progress made in matters relating to public health
during the past sixty years. The Lord Mayor of London will
preside, and the Sheriffs are expected to attend in state. On the
four Wednesdays immediately following, the Harben lectures will
be delivered at King’s College, London, by Dr. G. Sims Woodhead,
who will discuss the bearing of recent bacteriological investigations
on public health work, especially in connection with the diagnosis
and treatment of diphtheria, the stamping out of tuberculosis, and
bacteriological filtration.
Fire-Resisting Decorations and other materials made from
asbestos have recently been exhibited in St. James’s Hall, the
exhibition having been organised by the United Asbestos
Company with the view of showing how such disasters as that
which recently befel in Paris may be averted by the use in public
buildings and other places of non-inflammable substances for
constructive and decorative purposes. One feature in' the display
took the form of what are described as “ salamander ” decorations*
in tli way of friezes, dados, ceilings, and the like, made wholly
from asbestos, while specimens were also shown of the mineral in
its crude state. A great variety of articles made of this substance
were exposed to the action of flame, and showed such power of
resistance as to demonstrate conclusively the uninflammable
character of the material employed.
PARLIAMENTARY NOTES AND NEWS-
The Excise Licences Bill brought before the House of Lords
by Viscount Peel is a valuable addition to the efforts which have,
rather too spasmodically, been made in the direction of statute
law revision and codification. Viscount Peel thinks that there is
no necessary bond of union between legality and complexity, and
he has, therefore, identified himself with the task of drafting a Bill
which shall weld together in one harmonious whole the surviving
clauses of some seventy-five statutes, ancient and modern, relating
to the duties payable on excise licences. The magnitude of the
task is faintly conveyed by the mention (in a schedule to the Bill)
of the enactments to be repealed, and it may serve as the measure
by which one may judge the practical need for consolidation.
No Amendment of the Law is attempted in the Bill, nor does
it deal with the vexed question of licensing by justices. The
clauses are arranged in five parts ; in fact, they seem to separate
naturally into that arrangement. Part I. deals with general
regulations applicable to all excise licences — form of licences, etc.
Part II. treats of regulations affecting licences for trades and manu¬
factures generally, for example, transfers, definition of retailing,
provision as to partnerships, plurality of premises, and so forth.
Part III. takes more specific ground, and occupies itself
with particular trade licences, such as those for stamped
medicines, methylated spirit, stills, sweets, vinegar-making, and
the sale of wines. Part IV. has for its scope all excise licences
other than those relating to trade, e. g. , dog, establishment, and
gun licences. Part V. is supplemental, and “rounds off” the
admirable compilation of fragmentary statutes by bringing
together the various regulations as to forms, notices, and registers
in respect to certain licences. Those who make the nation’s laws
sometimes confer doubtful benefits in the exercise of their legis¬
lative functions, but there can be no doubt that the man who has
succeeded in evolving form and lucidity from the chaos of excise
enactments is entitled to rank among the foremost of public bene¬
factors.
The Select Committee on the Companies Bill has been
resting some time now, and there is no present indication of
resuming. The evidence already taken this session has been almost
entirely legal, and the effect of it has apparently been to lead the
Committee to seek refuge from its embarrassments in a term of
“masterly inactivity.” Efforts have been made to approach the
Committee with reference to the protection of personal qualifica¬
tions, but everything points to the fact that in the amendment of the
Companies Acts the Board of Trade has undertaken a much harder
task than it can possibly carry through, at any rate this Session.
The Copyright Amendment Bill has passed its second reading
in the Upper House, and now awaits consideration by a Select
Committee. The members of the Committee will be Viscount
Knutsford and Lords Hatherton, Tennyson, Monkswell, Hobhouse,
Thring, Farrer, Welby, and Pirbright.
Licensing (Scotland) Acts Amendment Bill. — Any chemist
can obtain from the pages of his Pharmaceutical Journal
abundant evidence that the Pharmacy Act is not the same
public protection in Scotland as it is in England, and the
difference in legal procedure between two portions of the same
country has now revealed another disadvantage, in reference
to the sale of alcoholic beverages during prohibited hours. It is
possible, it seems, for Glasgow shopkeepers (one does not know
whether they are chemists) to sell, even on the Sabbath, British
wines or “ sweets ” containing as much as 27 per cent, of alcohol.
In fact, the inhabitants of the second city of the empire are said to
be developing quite an unpatriotic taste for British-made and
Sunday-bought wines. Neither the Procurator Fiscal, the police,
nor the Inland Revenue authorities can stop this irregular Sunday
traffic, for “ sweets ” in Scotland are not “ excisable liquors ”
within the meaning of the licensing laws. The Amendment Bill
now introduced proposes to check the recently-discovered evil by
assimilating the law in Scotland to that in England, and providing
that licences for the sale of sweets and made wines shall only be
given in conformity with a magistrate’s certificate previously
obtained. The certificate would prohibit the Sunday sale of the
27 per cent, of alcohol, and would, it is hoped, save Glasgow fropi
pioral deterioration,
June 12, 1897]
PHARMACEUTICAL JOURNAL.
519
THE WORLD OF PHARMACY.
British Pharmaceutical Conference (Executive Com¬
mittee), Wednesday, June 2. — Dr. Symes, President, in the chair.
• — The minutes of the previous meeting were read and confirmed.
—By the kindness of the Local Secretary a printed copy of social
Arrangements oe the Glasgow Meeting
was submitted and considered, and with one or two suggested altera¬
tions, approved. It was briefly as follows : — Monday, August 9,
reception by the President at 8 p.m. at the Corporation Art Gal¬
leries, to be followed by a conversazione. — Tuesday, August 10,
opening meeting of Conference in the hall of the Grand Hotel at 10
.a.m., when a welcome will be given by the Honourable the Lord
Provost, to be succeeded by the Presidential address and the
reading and discussion of papers. Luncheon will be provided
at 1 p.m. on this and the day following at the Grand Hotel, which
will be the headquarters of the Conference. The reading of papers
will be resumed at 2 p.m., and at 4 o’clock there will be an
.excursion to Loch Lomond. — On Wednesday, June 11, the sessions
of the Conference will be resumed at 10, and at the conclusion of
the afternoon sitting it is proposed to drive to the Glasgow
Corporation Waterworks at Mugdock. In the evening there will
be a smoking concert and a drawing-room entertainment at the
same hour. — As usual Thursday will be devoted to the excursion,
which is to take the form of a day’s cruise on the Firth of Clyde,
the Western lochs, and through the Kyles of Bute. — A list of
officers for the ensuing year was drafted for recommendation to the
general meeting. — It was announced that Mr. W. E. Smith of
Ootacamund had consented to act as honorary secretary for
Madras. — Thirty gentlemen having been duly nominated, were
elected to membership.
Midland Pharmaceutical Association, Thursday, June
3, Mr. F. J. Gibson, President, in the chair. — The annual general
meeting of the members of this Association was held at the Grand
Hotel, Birmingham — The Council submitted a detailed report of
The Work of the Year,
and accompanying it a reprint of Dr. T. Wilson’s paper entitled
“ Doctors and Medicine Men,” which was read before the members
on February 9. The report of the Trade Committee contained in
the document has appeared in a recent issue of the Journal. — The
Hon. Librarian (Mr. J. Barclay) in his report stated that the
> Council desired to express the best thanks of the Association to the
donors of books. During the year there had been added the
Pharmaceutical Journal (presented by the Pharmaceutical Society),
‘ Calendar of the Pharmaceutical Society ’ (ditto), ‘ Year Book of
Pharmacy, 1896 ’ (presented by the Pharmaceutical Conference),
and J. Mitchell Bruce’s ‘ Materia Medica and Therapeutics ’
(presented by the Hon. Librarian). — In moving the adoption
of the report the President said that it was so full that
it did not require any words of his to bring it to their
notice. They had held nine meetings altogether, including
the annual supper. The opening meeting and the ball were very
successful and enjoyable, and the papers read by Mr. Barclay,
Mr. Liverseege, and Mr. Alcock were important ones.
The paper read by Dr. Wilson was thought so important by
the Council that they decided to print it in full. — Mr.
A. Southall seconded the motion, and said that he was
pleased to see they had been rather more successful than usual,
but still the scientific part of the work did not go down quite as
well as it ought. They wanted a little more power in compelling
the students to work. When they got the curriculum he supposed
they would do better in that way, but that seemed to be far off
yet. Parliament was so much engaged with other matters that
they found it difficult to get heard at all in the House of Commons.
A fresh feature in the report was the record of the doings of the
Trade Committee. That body seemed to have done good work,
and Birmingham had been honoured by one of their members
being elected President for the year. The members of theP.A.T.A.
had already shown their power at the Pharmaceutical Society’s
Council election. Mr. Carteighe, one of the most popular men in
the Society, occupied an unusually low position in the voting list
because he had not joined theP.A.T.A. He hoped that experience
might prove of use in getting him to join the movement. At
t resent the members of the Association were comparatively few,
but chemists were very backward. If they combined in larger
numbers the Association might become a great power in the country,
and instead of losing on the sale of proprietary articles they might
be able to make a small profit. — Mr. Weaver supported the motion.
— Mr. C. Thompson said that as an old secretary he thought the
present report was one of the best that had been sent out, at all
events, for something like sixteen or seventeen years. It was
one of the most complete they had had, and from what he had
heard during the last few days whilst going round Birmingham
on business connected with the Benevolent Fund, it had given
general satisfaction, and would be the means of getting them new
members. He had already booked three new members from the
fact that through the report they saw the Association was doing
good work. He desired to point out that the Ball balance of
£6 3,5. 9c?. could very well be increased to £26 if the
stewards threw a little more energy into their duties,
and did not leave the whole of the work to be performed by two
or three. There was no reason why the Ball should not become a
valuable asset of the Association. There was no mention in the re¬
port of the recreation section. He had the cricketing requisites, and
would be pleased to hand them over at any time. Sufficient interest
had not been shown in the section by the members to warrant
the arrangement of matches. He saw no reason why, in this
jubilee year, they should not go a little outside their
ordinary course and hold a garden party or some¬
thing of the kind, and with a, little energy they might very
well organise excursions during the summer months. — The report
having been agreed to, Messrs. F. H. Prosser and H. Shorthouse,
who acted as scrutineers, handed in
The Voting Papers,
which showed that the retiring members of the Council
were re-elected with the exception that Mr. F. Smith took
the place of Mr. Jarvis for Handsworth, and Mr. G. John¬
son that of Mr. Winfield for North Warwickshire. — Mr. A.
C. Weaver moved “That the best thanks of the Associa¬
tion be given to those firms who have supported the P.A.T.A.
movement.” He thought when they got gentlemen like Mr.
Southall in sympathy with that movement that it was making
great headway towards achieving the object they desired to accom¬
plish. He thought if they were all united in
An Association Like the P.A.T.A.
they would be able to carry on their businesses much better
than under the present conditions. No doubt what had
fallen from Mr. Southall would have some weight in inducing
members of the Pharmaceutical Association to join the movement.
— Mr. G. H. Brunt seconded the resolution, and said that he thought
the action of the Midland Pharmaceutical Association in
supporting the P.A.T.A. had met with the approval
of the whole of the retail trade. He thought all
those who benefited by the action of the Association
ought to support that and the P.A.T.A. also. — The President said
that all the firms who had joined that movement were deserving
of their best thanks. Those of them who were in the retail trade
knew what difficulties they laboured under, and they wanted to
get a profit if they could, and as far as he could see, there was no
means of getting it except through the P.A.T.A. The Pharma¬
ceutical Journal thought it was undesirable they should combine
with grocers, but they were not combining with grocers who sold
drugs, only those who sold articles everyone could sell by paying
five shillings a year to the Government. At the present time many
of those articles were being sold at cost price, and some for less,
and if theP.A.T.A. became strong enough to alter that state of
things it was worthy of their support. The resolution was carried.
• — Mr. C. Thompson moved that the incoming Council should be
instructed to reconsider Rule 6, having reference to
The Interviewing of Candidates
in the various Parliamentary Divisions. The motion was
seconded by Mr. Prosser and agreed to. — Mr. G. E. Perry
proposed a vote of thanks to the President and officers for their
services during the year. He said that the report this year
showed decided elements of progress. The year had not been a
very busy one, but they had every reason to congratulate them¬
selves. They were moving onwards and that was something to say
for pharmacy. — Mr. W. Scott seconded the proposition, which was
carried. — The President briefly replied.
520
PHARMACEUTICAL JOURNAL.
[June 12, 1897
The Annual Supper.
was held later in the evening, when Mr. Gibson took the chair.
The toast of “ The Queen” having been loyally honoured, Mr. C.
Thompson (local secretary) proposed—
“The Pharmaceutical Society’s Benevolent Fund.”
He said it was quite unnecessary for him to say very much as
to what that valuable Fund was doing for pharmacists and their
widows, as it was so well known to all present. He was pleased to
say that Birmingham had done fairly well so far with subscriptions,
though not so well as Manchester and Liverpool. Fifteen of the
old subscribers had doubled their subscriptions, there were twenty-
five new ones, and three donations. As the time had been
extended to the end of June before the special Jubilee
Fund was closed, he sincerely hoped and believed that the
list would be considerably increased. — Mr. A. Southall,
in responding, urged all to give a subscription, and said
it was the half-crown and five shilling subscribers that
he wished to see increased, as he thought every chemist should
give something. He also urged the claims of the Orphan Fund.—
Dr. T. Wilson proposed
“The Midland Pharmaceutical Association.”
Having expressed the pleasure he had in being present, he said
that anything which tended to bring pharmacists and the medical
profession together was a step in the right direction. He knew
their Association was doing its best, and he was pleased to find
the members combining to get just rewards for their labours.
In his profession they were doing the same, and by com¬
bination they could do a good deal. It was necessary in
these days that Associations such as that should exist. — The
President in responding, thanked Dr. Wilson for the
kind way in which he had referred to the Association. They were
trying to cultivate a closer union between the medical profession
and pharmacists, and they were also doing the best they could for
their members. There remained much to be done, and he hoped
the members would give the Council their loyal support in the
work in which they were engaged. — The proceedings were
enlivened by an excellent musical programme.
Edinburgh District Chemists’ Trade Association,
Monday, June 7.— Mr. John Bowman, President, in the chair. —
The fifth annual meeting of the Association was held in the Phar¬
maceutical Society’s House, 36, York Place, Edinburgh. The
minutes of last meeting were read and approved. — The Honorary
Secretary (Mr. C. F. Henry) read the
Annual Report and Financial Statement.
The membership remained sixty-five, as last year. There was
nothing specially eventful to record. During the year the Asso¬
ciation had instituted an exchange among members of out-of-the
way articles and proprietaries, which were only sent out in fairly
large quantities, although retailers often wanted only a small
quantity. The plan had been found useful so far. It had
been suggested that the scheme should be extended to
include certain proprietary medicines which could be pur¬
chased on more favourable terms in large quantities, but the
Committee after due consideration did not consider it advisable to
enlarge the scope in this way. The annual excursion to Loch
Lomond in conjunction with western pharmacists had, not¬
withstanding unfavourable weather, been very pleasant and
financially successful. The fourteenth annual ball had also been
successfully carried out, and showed a small balance. The
financial statement showed an income of £129, and an expenditure
of £120, and with the balance from last year there was now a
balance of £56 9s. 9 cL. in favour of the Association. — On the motion
of Mr. McLaren, seconded (by Mr. MacDougall the report
was unanimously adopted. — The Chairman said they had
now to consider what should be done with the balance
in hand. This was the year of Jubilee celebration of Her
Majesty’s record reign, and there had been some suggestion that
they mi uht signalise the occasion by increasing considerably the
sum to be voted to the Benevolent Fund of the Pharmaceutical
Society. It was for the members now to say what they thought in
regard to the matter. — Mr. Lunan moved and Mr. McLaren
seconded that the Association give £5 5s. to the Benevolent Fund
and £2 2s. to the Orphan Fund of the Pharmaceutical Society.
The motion was unanimously agreed to. — The Chairman reported
that all the arrangements had been completed for the annual
excursion to St. Mary’s Loch on Thursday, 10th inst., and
it was expected that about 100 would be there.— After
discussion Mr. McLaren withdrew a motion to separate the
offices of Secretary and Treasurer, of which he had given notice.
— On tjie motion of Mr. Henry, seconded by Mr. Lunan, it was
agreed to appoint a committee to consider and report to next
meeting as to the desirability of offering a prize or prizes to be
competed for by assistants or apprentices as a means of advan¬
tageously expending some portion of the Association’s funds. The
President, Vice-President, Secretary, and Messrs. Burley and
Lunan were appointed a Special Committee for this purpose. The
following office-bearers were elected for next year : — John Bow¬
man, President ; David MacLaren, Vice-President ; Claude F.
Henry, 1, Brandon Terrace, Hon. Secretary and Treasurer ; and
Messrs. Anderson, Boa, Forret, Glass, R. L. Hendry, D. McGlashan,
J. McGlashan, \\ ylie, Smith, Macpherson, McDougall, and Lunan,
as members of Committee. The meeting closed with a vote of
thanks to the retiring office-bearers, and especially to the Secre¬
tary for the diligence and zeal with which he had discharged the
duties during the year.
Edinburgh Chemists’, Assistants,’ and Apprentices^
Association, Friday, June 4. — More than thirty members left
Caledonian Station for Colinton by the 8.30 p.m. train for the first
botanical excursion of the season. Mr. Duncan, who was to con¬
duct the excursion, was not able to go all the way, but his place
was ably filled by Mr. C. A. Macpherson. The weather was very
cold for the season, and vegetation generally was much behind,
but the outing was greatly enjoyed by all who attended. The
route was by Colinton Dell and Redliall, returning by Slateford. The
following were gathered in flower : — Ranunculus ficaria, R. bulbosus.
Gardavnne pratensis, Sinapis arvensis, Viola canina, Lychnis diuma,
Stellaria holostea, Ulex europceus, Cytisus scoparius, Orobtis-
tuberosus, Geum urbanum, G. rivale, G. intermedium, Alchemilla
vulgaris, Sanicula europcea, Anthriseus temulentum, Valeriana
pyrenaica, Doronicum pardalianches, Symphytum tuberosum, Vero¬
nica chamiedrys, Lamium album, Primula vulgaris, Mercurialis-
perennis, Urtica dioica, Gonvallaria majalis, Agraphis nutans,
Allium ursinum, and Luzula sylvatica.
Pharmaceutical Society of Ireland (Meeting of the
Council), Wednesday, June 2. —Mr. W. F. Wells, Junior, Presi¬
dent, in the chair. — A letter was read from Mr. Charles Evans,
thanking the Council for its kindness in asking him to withdraw
his resignation, but declining to do so. — On the motion of Mr.
Conyngham, seconded by Mr. Whitla, the resignation was
accepted with great regret. — On the motion of Mr. Grindley,,
seconded by the Vice-President, Mr. William D. Porter,M.P.S.I.,
of Phipsborough, near Dublin, was co-opted a member of Council
in the room of Mr. Evans.
Futile Prosecutions,
A letter from the Under-Secretary, Dublin Castle, intimated -
that the Lord Lieutenant had reduced the fine imposed on
the Enniscorthy Co-operative Agricultural Society, Limited,
for an unlawful sale of sheep dip, from £5 to £3. — The President
said it seemed to him that there was really very little use in-
the Society spending time and money in prosecuting at
all. The Castle authorities seemed determined that law¬
breakers should go scot-free. — Professor Tichborne : Do they give
any reason? — President: No reason whatever. Lately a poor
ignorant woman was fined £5 for selling ether, but neither the
magistrates nor the Castle had any pity on her. — Mr. Bernard:
Did she appeal to have the penalty reduced ? — President : No.
The law was carried out in her case because she sold a thing that
affected the excise. In the Enniscorthy Company case the Inspector
of Police stated that as much arsenic was sold as would poison-
1600 people. That prosecution cost us £12, and we get £2. I
told a magistrate in England a few of the cases that have come
under our notice, and he could hardly credit that such
things were allowed to happen in this country. — Mr. Bernard :
Was he an Irish magistrate ? — President : No ; an English
magistrate. — Mr. Bernard : He would want to be
Irish in order to understand this country. — Mr. Conyng¬
ham said he did not see why they should waste
the funds of their licentiates for the benefit of the Govern¬
ment.- — The President said the Chairman of the company in
question was one of the magistrates, and he had not the manliness
to sign the defendant’s memorial, but let the Vice-Chairman,.
June 12, 1897
PHARMACEUTICAL JOURNAL.
521
•whose name was Codd, sign it. The Secretary’s name was Death.
The whole proceeding meant “ death ” to the Society and a
codd” to the law.
Apothecaries as Pharmaceutical Chemists.
Dr. Arthur Henry Hadden, proprietor of the Medical Hall,
Wexford, applied to be registered as a pharmaceutical chemist.
His letter stated that he was a fully qualified medical man, and
also held by examination the degree of the Apothecaries’ Hall,
Dublin. He also enclosed a declaration of apprenticeship to a
pharmaceutical chemist. In the course of discussion it was
stated that at the Apothecaries’ Hall medical men were being
registered who had no practical experience in pharmacy, and also
that they were not being registered under the Act of 1791,
which is specially referred to in the clause of the Pharmacy Act
that authorises the registration of apothecaries. — It was
resolved, on the motion of the Vice-President, seconded by Mr.
Grindley, that Dr. Hadden’s application should not be
acceded to unless he could show that he was a licentiate
■of the Apothecaries’ Hall under the Act of 1791, and
also pending a reply from the Apothecaries’ Hall to a deputa¬
tion from the Council. — A letter from Mr. Alexander Knox
McIntyre, Official Assignee of the Irish Bankruptcy Court,
.stated in reference to the appointment under that Court of
a general manager over the business of an arranging debtor,
who was a registered druggist and qualified to sell poisons,
that the principal business of the debtor was hardware, and that
the manager would not be allowed to interfere in his drug depart¬
ment, the business of which would continue to be looked after by
.the debtor himself. — Mr. A. L. Doran was re-elected Examiner in
Pharmaceutical and General Chemistry. — Other business having
Been disposed of, the Council adjourned.
Plymouth, Devonport, Stonehouse and District
Chemists’ Association, Wednesday, June 2. — The annual
outing of this Association was attended by a party of seventy, who
mustered at Millbay and Devonport stations, le